Digital Commons Network^™

Hyflex On The Go: The Mobile Hyflex Project At Tu Dublin, Frances Boylan, Ciara Bell

Papers, presentations and other resources

Background:

Under Stream 3 of the N-TUTORR project and work package 3.2 Digital Campus, the Digital Education Team at TU Dublin worked closely with the N-TUTORR Digital Campus Lead to fund and establish a number of HyFlex related projects. The Mobile HyFlex Project was one of these and set out to explore and evaluate the provision of quality delivery in teaching spaces traditionally ill-equipped for such a flexible mode. The project attracted the attention of staff from across all three campuses with 90 applying to be involved. In May 2024, 50 staff were issued with a MS Surface Pro and …

Simple Improvements In Vector Design Afford Substantial Gains In Aav Delivery Of Aggregation-Slowing Aβ Variants, Ella Borgenheimer, Cameron Trueblood, Bryan L Nguyen, William R Lagor, Joanna L Jankowsky

Faculty, Staff and Students Publications

Adeno-associated virus (AAV) gene therapy for neurological disease has gained traction due to stunning advances in capsid evolution for CNS targeting. With AAV brain delivery now in focus, conventional improvements in viral expression vectors offer a complementary route for optimizing gene delivery. We previously introduced a novel AAV gene therapy to slow amyloid aggregation in the brain based on neuronal release of an Aβ sequence variant that inhibited fibrilization of wild-type Aβ. Here we explore three coding elements of the virally delivered DNA plasmid in an effort to maximize the production of therapeutic peptide in the brain. We demonstrate that …

Increased Thermal Stability And Retained Antibacterial Properties In A Sulbactam And Amantadine Salt: Towards Effective Antibacterial-Antiviral Combination Therapies, Josephine Bicknell, Ivan Bondarenko, Alice Colatrella, Elani J. Cabrera-Vega, Jesus Daniel Loya, Delbert S. Botes, Jay L. Mellies, Gonzalo Campillo-Alvarado

Chemistry Faculty Publications and Presentations

A clinically relevant multidrug solid comprising sulbactam (β-lactamase inhibitor) and amantadine (antiviral) displays enhanced thermal stability and sustained antibacterial activity compared to starting materials.

We describe the formation of a multidrug salt comprising sulbactam (SUL, β-lactamase inhibitor) and amantadine (AMNH, antiviral). Physicochemical investigation of the SUL·AMNH salt revealed enhanced thermal stability compared to pristine starting materials. In vitro studies found that salt formation in SUL·AMNH does not disrupt antibacterial activity against model organisms Escherichia coli and Staphylococcus epidermidis. To our knowledge, we show the first β-lactamase inhibitor-antiviral salt where both components have been approved by the U.S. Food and Drug …

Evaluating The Perceived Benefits Of Education In Revenue Cycle Management And The Impact On Medical Claims Reimbursement, Jessica L. Miller

Student Dissertations

Efficient Revenue Cycle Management (RCM) is essential for healthcare organizations to ensure timely and accurate reimbursement for medical claims. The research problem was the significant inadequacies in RCM process in medical billing that has resulted in financial burdens imposed on providers, patients, and the organizations that provide medical services. There are clearly identified educational gaps in RCM that contribute to claim denials, delays, and revenue loss, underscoring the need for robust training programs. The purpose of this study was to explore the perceived impact of education in RCM on medical claim reimbursement outcomes within the U.S. healthcare system. The study …

Imlunestrant, An Oral Selective Estrogen Receptor Degrader, As Monotherapy And In Combination With Targeted Therapy In Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Phase Ia/Ib Ember Study, Komal L Jhaveri, Cynthia X Ma, Et Al.

2020-Current year OA Pubs

PURPOSE: Imlunestrant is a next-generation oral selective estrogen receptor (ER) degrader designed to deliver continuous ER target inhibition, including in

METHODS: An i3+3 dose-escalation design was used, followed by dose expansions of imlunestrant as monotherapy or in combination with abemaciclib with or without aromatase inhibitor (AI), everolimus, or alpelisib. Imlunestrant was administered orally once daily and with the combination partner per label.

RESULTS: Overall, 262 patients with ER+/HER2- ABC were treated (phase Ia, n = 74; phase Ib, n = 188). Among patients who received imlunestrant monotherapy (n = 114), no dose-limiting toxicities or discontinuations occurred. At the RP2D (400 …

Happiness At Work – How Workplace Spirituality Contributes To Employee Wellbeing, Amarendra Nath Misra, Mohammad Israrul Haque, Gaurav Tripathi

Management Dynamics

Workplace spirituality is associated with employees looking for meaning, self-transcendence, inclusion, values, ethics, and protection of one's religious beliefs. The study aimed to review literature about Spirituality in the workplace and employee wellbeing, find definitions of both constructs and enumerate studies that have shown the connection between the two constructs. The findings of the research paper suggest a strong connection between the workplace and employee wellbeing, which benefits employees, enhances organisational performance, and improves employee wellbeing and, thereby, the quality of their lives. The paper introduces workplace spirituality, provides a sense of purpose and meaning at work, and suggests that …

A Survey Of Root Canal Treatment In Kurdish Community: A Pilot Study, Adil Othman Abdullah

Polytechnic Journal

Objective To analyze and describe the techniques and procedures employed in root canal treatment in the Kurdistan Region.

Method This study was conducted in 2023 and involved a simple random sample of 210 dentists/endodontists practitioners. The survey was spread throughout both private and governmental sectors in three distinct locations within the Kurdistan Region. The study aimed to enhance dentists' awareness and knowledge of the latest devices and advanced techniques used in the field of endodontics. The data were evaluated using basic summary statistics.

Results The eighty seven percentage of the practitioners responded. The majority of participants reported using step-back instrumentation …

Transgender And Gender-Queer People Belong In Jesuit Higher Education, Morgan Keating, Konstantin Platonov

Jesuit Higher Education: A Journal

This paper explores the intersection of Jesuit values and the experiences of transgender and gender-queer campus community members in Jesuit higher education institutions. Despite the adoption of inclusive policies, campus climates often lack the support of minorities, leading to discrimination and deterioration of their mental health. The core Jesuit values—cura personalis, magis, discernment and reflection, service rooted in justice and love, and solidarity and kinship—are examined as the principles that should drive more active inclusion and support. The paper also suggests practical steps to align institutional practices with these values better. By embracing these measures, …

Physician Assistant Students As Agents Of Change Through Service-Learning Opportunities, Kelli Frost ,Ms, Pa-C, Nour Lyon ,Ms, Pa-C, Arthur Ko ,Phd, Claire Barry ,Pa-S, Michael Martin ,Mals

Jesuit Higher Education: A Journal

Community outreach and the integration of cultural competency are essential to the education and development of healthcare professionals. This article describes incorporating service-learning into a course at a Jesuit and Mercy institution as a method of building cultural competency into a Physician Assistant (PA) curriculum. The project examined how service-learning impacted students’ understanding of community needs and allowed students to reflect on their values. In addition, it aimed to inspire students to build connections with vulnerable populations and have concern for the poor and marginalized. Students participated in service opportunities with a community partner to identify and meet the needs …

Cura Communitatis In The Time Of Coronavirus, Jeffrey Labelle

Jesuit Higher Education: A Journal

This study conceptualizes cura communitatis as a contemporary bridge between cura personalis and cura apostolica for Jesuit higher educational institutions. A review of related literature suggests this concept as a possible means for Jesuit IHEs to respond to the realities of the coronavirus pandemic and the psychological, social, spiritual, and economic challenges which have resulted from dealing with this global health crisis. The author surfaces the shared desire in AJCU institutions to care for one another and our shared relationships as pilgrims during a global phenomenon that has demanded physical distancing. The study explores the ways in which this desire …

Teaching Ettingerian Matrixial Theory, R. Michael Fisher

Artizein: Arts and Teaching Journal

Utilizing an adapted scoping review of the literature on Bracha L. Ettinger and Education (2008-2024), the author reveals the specific ways that Ettingerian Matrixial Theory (EMT) and its pedagogies are taught and can be taught in the future. EMT is argued to be a new branch of Critical Theory. The current literature shows there is mostly engagement with EMT in academic settings. As well, the literature reviewed shows EMT is used readily in arts and with artists as teachers and teachings for adults. However, the author unveils diverse other possibilities of teaching EMT. A few major themes from the literature …

Weaving Care Threads: Matrixial Encounters In Teacher Professional Learning, Misty Paterson

Artizein: Arts and Teaching Journal

The need for increased care in today’s classrooms is becoming undeniable. Yet, teacher shortages, budget cutbacks, and mental health crises makes injecting care into our field feel evermore demanding and depleting. What if abundant and systemic care was at our fingertips? This article shares the voices and processes of six seasoned, “non-artist” educators as they co-created a learning space that prioritized a relational, social-based, caring sensibility through art-care practices. The author brings the lens of Ettinger's Matrixial Theory to her practitioner inquiry into caring affect through Spontaneous Creation-Making (Bickel & Fisher, 2023) with promising and pragmatic implications for teacher educators.

Editorial: Pedagogical Reorientation For The Twenty-First Century, R. Michael Fisher, Barbara Bickel

Artizein: Arts and Teaching Journal

In this special issue, Ettingerian Matrixial Theory, Education and the Arts our intention is to attune with and bring together the cross-currents of creative and scholarly works that are emerging internationally between Ettingerian Matrixial Theory (EMT), Education and the Arts.

Full Issue_ Artizein_2024, R. Michael Fisher, Barbara Bickel

Artizein: Arts and Teaching Journal

This special issue, Ettingerian Matrixial Theory, Education and the Arts attunes with and brings together the cross-currents of creative and scholarly works that are emerging internationally between Ettingerian Matrixial Theory (EMT), Education and the Arts.

Enrom - Consumer Staples Fund - Investment Research Report, Joao Moraes Barreto, Adnan Aldaas, Farheen Saiyed, Sofia Martinez De Arredondo Mil, Michael Hannosh

Undergraduate Research and Engagement Symposium

The ENROM fund was a sector-focused mutual fund concentrating on the consumer staples industry, aimed at generating excess returns relative to a predefined benchmark over an 11-week trading period. Our investment strategy prioritized diversified holdings within the consumer staples sector, emphasizing stocks with strong fundamentals, stable cash flows, and resilience to economic fluctuations. The fund employed a rigorous selection process, leveraging fundamental and technical analyses to identify undervalued assets while adhering to strict compliance guidelines, including the fully invested rule and leverage constraints. Performance metrics, such as alpha, tracking error, and standard deviation of returns, were systematically monitored to align …

Economic Eagles Mutual Fund, Axel Hernandez

Undergraduate Research and Engagement Symposium

The Economic Eagles Mutual Fund achieved a 6.7% portfolio return despite adhering to large-cap equities investment constraints. This presentation demonstrates our trading strategies across different sectors, which include valuation techniques such as Dividend Discount, Free Cash Flow to Equity, and technical analysis. Despite challenges such as sector volatility, our research-driven process allowed for informed investment decisions, including profitable trades in Nike and Microsoft. Key findings include the importance of diversifying strategies and adjusting to market changes. This program focuses on the practical application of portfolio management theory and team effort to produce good investment results.

Maniac Mid Cap Final Report, Christina Zua, Alexa Brodeur, Fernando Campos

Undergraduate Research and Engagement Symposium

This semester, we had the opportunity to invest in Midcap stocks and complete trade reports throughout the way. This report demonstrates an analyzation of our portfolio performance and comparing the metrics to the benchmark.

5bf- Financial Payments Fund, Ryan Hensley, Noah Streefland Erdem, Ioan Cardos, Santiago I. Yepez, Kabir Farishta

Undergraduate Research and Engagement Symposium

We are running a financial payments sector fund, investing 10 million USD, and doing research on these trades.

Gender Segregation In Caring Labor: The Impact Of Social Norms On Career Choices, Evelyn Xinhui Cheng

CBER Conference

Women engage in work stereotypically seen as "women's work," or work based on the perceived "natural" female tendency towards caring and relational thinking (Tung 2000). In pre-reform China, Shu (2005) found that women were more concentrated in the lowerpaying collective sector compared to men in the state-owned sector, contributing to the gender wage gap. China's horizontal occupational segregation by gender has significant implications for gender pay gaps, workforce attachment, and the perceived value of caring labor in society. Feminist scholars argue that gendered norms around caring originate that conflate womanhood with nurturing (England 2005; Litt & Zimmerman 2003). The main …

Impact Of Pathogenic E. Coli In Drinking Water On The Well-Being Of Children, Aysha Khatoon

CBER Conference

Despite global advancements, unsafe drinking water is a major cause of illness, ranked as the eighth highest worldwide (Forouzanfar et al., 2015). Studies indicate that even improved water sources, can harbour faecal contamination (Shaheed et al., 2014; Bain et al., 2014b). Globally, 1.8 billion people rely on drinking water contaminated with faecal matter (Bain et al., 2014a), with pathogenic E. coli being a primary concern. In Pakistan, the situation is dire. About 25 million people, particularly children, suffer due to open defecation, leading to 53,000 child deaths annually from diarrhoea (UNICEF, 2021). Pathogenic E. coli is a significant contributor to …

Investigating The Effect Of Active Living Wall On Indoor Air Quality And Energy Consumption: Case Study In Uaeu Closed Offices, Atina Ghunaim

Thesis/ Dissertation Defenses

Extreme hot climates can significantly affect indoor air quality (IAQ) and ventilation, resulting in higher energy demands. Numerous studies have demonstrated that outdoor greening, such as trees and landscaped areas, can reduce a building’s energy consumption. However, less research has been conducted on the impact of indoor vegetation on energy use and air quality. Indoor vegetation decreases carbon dioxide (CO₂) concentration by absorbing and releasing oxygen (O₂), while the evapotranspiration process further enhances (IAQ) and reduces energy expenditure. The United Arab Emirates has dry arid climate and summers with high humidity levels, causing individuals to stay longer indoors, which is …

Tarrant County Archeological Society News, Vol. 8, No. 12, 1994, Editor's Material, Bryan Jameson

North Texas Archeological Society Records

Editor's draft of volume eight and issue twelve of Tarrant County Archeological Society News.

Tarrant County Archeological Society News, Vol. 8, No. 11, 1994, Laurie Moseley

North Texas Archeological Society Records

Volume eight and issue eleven of Tarrant County Archeological Society News.

Tarrant County Archeological Society News, Vol. 8, No. 12, 1994, Bryan Jameson

North Texas Archeological Society Records

Volume eight and issue twelve of Tarrant County Archeological Society News.

Tarrant County Archeological Society News, Vol. 8, No. 10, 1994, Editor's Material, Bryan Jameson

North Texas Archeological Society Records

Editor's draft of volume eight and issue ten of Tarrant County Archeological Society News.

Tarrant County Archeological Society News, Vol. 8, No. 10, 1994, Bryan Jameson

North Texas Archeological Society Records

Volume eight and issue ten of Tarrant County Archeological Society News.

Tarrant County Archeological Society News, Vol. 8, No. 9, 1994, Tarrant County Archeological Society

North Texas Archeological Society Records

Volume eight and issue nine of Tarrant County Archeological Society News.

Tarrant County Archeological Society News, Vol. 8, No. 9, 1994, Editor's Material, Tarrant County Archeological Society

North Texas Archeological Society Records

Editor's draft of volume eight and issue nine of Tarrant County Archeological Society News.

Tarrant County Archeological Society News, Vol. 8, No. 8, 1994, Editor's Material, Tarrant County Archeological Society

North Texas Archeological Society Records

Editor's draft of volume eight and issue eight of Tarrant County Archeological Society News.

Tarrant County Archeological Society News, Vol. 8, No. 8, 1994, Tarrant County Archeological Society

North Texas Archeological Society Records

Volume eight and issue eight of Tarrant County Archeological Society News.