Digital Commons Network^™

Disney Adult Or Disney Cult?: Observing The Effects And Perceptions Of Transmedia Storytelling Onto Fandom, Sara Spradley

Cal Poly Humboldt theses and projects

Transmedia storytelling is the vehicle for narratives to become immersive to their audience through different modalities. The Walt Disney Company employs this form of storytelling by placing any one of its films in the context of attractions and live-action performances, or vice-versa, creating a convergent culture that will follow these products through every medium. This project views transmedia storytelling used by the Walt Disney Company as the reasoning for the Disney Adults' fandom interest in interacting with Disney products. Through the use of discourse analysis, and digital ethnography I will observe this relationship between the use of transmedia storytelling, fandom …

The Persistent Voice Of The Colonizer: Troubling A Mascot’S Settler-Colonial Past, Linda J. Kuckuk

Cal Poly Humboldt theses and projects

The legacy of settler-colonialism permeates American culture. Remnants of westward expansion remain in our societal divides, political differences, environmental inequities and economic inequalities. Conversations about decolonization, gentrification, and other ongoing practices that precipitate and uphold colonialism are notably found in literature, art, social structures, icons and symbols. Mascots that rely on stereotypes or caricatures can contribute to negative perceptions and reinforce discriminatory attitudes, making it necessary to reevaluate and change representational practices. In this analysis I apply historical, textual, and visual methods to explore Cal Poly Humboldt’s mascot Lucky Logger and identify how this character is a “persistent voice” by …

A Post-Colonial Criticism Of Ernest Callenbach's Ecotopia, Kaitlyn R. O'Dell

Cal Poly Humboldt theses and projects

The representation of Indigenous land-based cosmologies within Ernest Callenbach’s Ecotopia communicates a real perception of our world through the constructed imaginative society within this speculative fiction novel. Ecotopia is an alternative Pacific West Coast society that counters the dominant United States model in its holistic and green approach. This green society relies heavily on Indigenous ideology but lacks actual Indigenous voices or communities within this white idealized society. This research provides an example of the deconstruction of this popular novel to its main problematic components, establishing why the use of Indigenous beliefs and values can cause negative implications to the …

Beyond Exhausted: An Investigation Into Teacher Burnout And Teacher Attrition, Michael Carino Morales Sr.

Cal Poly Humboldt theses and projects

The role of a teacher is an important one. Teachers serve as educators, mentors, and guides for their students. Teachers often invest their time, energy, and emotions into their work. They do essential work and frequently receive little in return.

This thesis examines the many challenges that teachers face today. It focuses on teacher workload, financial pressures, curriculum debates, and the effects of the COVID-19 global pandemic.

The thesis is divided into three sections. It begins with my experiences as a public school teacher and my difficulties, such as heavy workloads and curriculum management. That is followed by the literature …

"Kindness Eases Change / Love Quiets Fear": Mapping Change And Movement In Octavia Butler's Parable Of The Sower, Elizabeth Hershey

Cal Poly Humboldt theses and projects

In this project I take a digital mapping approach to reading and analyzing Octavia Butler’s Parable of the Sower. A lot has been said about this novel’s relevance to our own world, and the ways it forces us to think about possible futures. To contribute to the conversations surrounding this novel, I add a digital humanities element to the conversation in order to see what digital mapping has to offer in the way of literary analysis and connecting this novel to our own world. Since the novel is so focused on movement and change, I mapped out the movement of …

“Bad At Reading”: Narratives Of Boys With Negative Reading Self-Concept, Aimee Talmadge

Cal Poly Humboldt theses and projects

There is a clear and consistent gender gap between students who view themselves as readers and those who do not (Love & Hamston, 2003). Overwhelmingly, young men report a lower self-perception of their ability and interest in reading and literacy, and this in turn impacts their growth and motivation in literacy learning. Through this study, I interviewed six students, specifically male high school students who self-identified as bad at reading or disliking reading. Through one-on-one interviews and focus groups, I explored how they viewed themselves as “non-readers” and why their reading self-perception is negative. The findings show how the lack …

Mouralherwaqh: Coastal Wetland Road Crossing Da’Luk, Filip Amborski

Cal Poly Humboldt theses and projects

The integration of Indigenous and Western science plays an essential role in Tribally led collaborations for land management. This process of woven sciences is rooted in reciprocal relations and partnerships guided by Tribal Nations. Our cohort was invited by Wiyot Tribal Representatives to investigate a culvert located within the wetlands of Mouralherwaqh— a parcel of land reacquired by the Wiyot Tribe in 2022. This document seeks to share our experience and analysis as part of the Wiyot Tribe’s broader journey in navigating ecocultural restoration projects within Mouralherwaqh. The four community interests we investigated for the wetland crossing included a resized …

Finding Connection: Teaching With Culturally Responsive Texts, Chloe N. Pounds

Cal Poly Humboldt theses and projects

Deciding which texts to teach in English Language Arts (ELA) classrooms poses challenges for educators. Traditionally, many teachers rely on established curricula, however, the increasing diversity of student populations highlights the need for texts that reflect student interests and backgrounds, as well as the need for culturally responsive pedagogical practices. To investigate student perceptions and benefits of culturally diverse texts, I created a short story unit and collected student reflections and teacher observations.

Alternative Shelter Evaluation Report, Jacen Greene, Todd Ferry, Emily Leickly, Franklin H. Spurbeck

Homelessness Research & Action Collaborative Publications and Presentations

This report summarizes research by Portland State University’s Homelessness Research & Action Collaborative for the Joint Office of Homeless Services on the cost, participant experiences, and client outcomes in village-style and motel shelters as compared to each other and to traditional, congregate shelters.

Mouralherwaqh Coastal Wetland Road Crossing Da'luk, Pakunihanich Nicoli Martin

Cal Poly Humboldt theses and projects

The integration of Indigenous and Western science plays an essential role in Tribally led collaborations for land management. This process of woven sciences is rooted in reciprocal relations and partnerships guided by Tribal Nations. Our cohort was invited by Wiyot Tribal Representatives to investigate a culvert located within the wetlands of Mouralherwaqh— a parcel of land reacquired by the Wiyot Tribe in 2022. This document seeks to share our experience and analysis as part of the Wiyot Tribe’s broader journey in navigating ecocultural restoration projects within Mouralherwaqh. The four community interests we investigated for the wetland crossing included a resized …

Mouralherwaqh Coastal Wetland Road Crossing Da'luk, Natalie Mendez

Cal Poly Humboldt theses and projects

The integration of Indigenous and Western science plays an essential role in Tribally led collaborations for land management. This process of woven sciences is rooted in reciprocal relations and partnerships guided by Tribal Nations. Our cohort was invited by Wiyot Tribal Representatives to investigate a culvert located within the wetlands of Mouralherwaqh— a parcel of land reacquired by the Wiyot Tribe in 2022. This document seeks to share our experience and analysis as part of the Wiyot Tribe’s broader journey in navigating ecocultural restoration projects within Mouralherwaqh. The four community interests we investigated for the wetland crossing included a resized …

Mouralherwaqh Coastal Wetland Road Crossing Da'luk, Romel Robinson Ii

Cal Poly Humboldt theses and projects

The integration of Indigenous and Western science plays an essential role in Tribally led collaborations for land management. This process of woven sciences is rooted in reciprocal relations and partnerships guided by Tribal Nations. Our cohort was invited by Wiyot Tribal Representatives to investigate a culvert located within the wetlands of Mouralherwaqh— a parcel of land reacquired by the Wiyot Tribe in 2022. This document seeks to share our experience and analysis as part of the Wiyot Tribe’s broader journey in navigating ecocultural restoration projects within Mouralherwaqh. The four community interests we investigated for the wetland crossing included a resized …

Beyond The Classroom: A Land-Based Approach To Outdoor Education, Jacquelyn R. Matthews

Cal Poly Humboldt theses and projects

This pilot project seeks to nurture space for Indigenous perspectives while equipping early childhood educators with tools for integrating diverse epistemology into outdoor learning practices to foster collaborative educational approaches. To align with this effort of shared knowledge, the project intends to offer a culturally sustaining educational tool that can help disrupt dominant approaches by evaluating alternative teaching strategies that center partnerships with local Indigenous communities to move toward equity-centered education. This can be achieved by modeling a resource guide after the theoretical underpinnings of Etuaptmumk Two-Eyed Seeing, and land-based pedagogy. A major component of this resource guide will include …

Adoption Of Holistic Education Practices: A Survey Of California K-12 Educator Experiences, Arianne M. Nova

Cal Poly Humboldt theses and projects

In a rapidly evolving educational landscape, the federal government must explicitly consider holistic approaches to education as essential for the well-being and future of students in public schools. Holistic education, which extends beyond traditional academics to nurture the 'whole child,' has garnered substantial support in the literature for its positive impact on academic performance, behavior, and student well-being. This research explores educator perspectives on holistic education in a K-12 California school district. By surveying teachers, counselors, school social workers, and principals within this district, I assess their awareness concerning structural levels, available resources, and implementation capabilities related to holistic education. …

Assessment Of Avian Community Structure And Habitat Connectivity In The Fanno Creek Corridor Bird Surveys, Habitat Assessment, And Management Recommendations, Grace Hall

Environmental Science and Management Professional Master's Project Reports

Urbanization can significantly impact habitat quality and connectivity for avian communities, decreasing species richness and diversity. However, in highly fragmented habitats, urban parks and riparian zones can provide important habitat corridors for birds that facilitate movement and access to essential resources. On the west side of greater Portland, Oregon, Fanno Creek may serve as a habitat corridor for birds and other local wildlife.

Fanno Creek is a 25-kilometer tributary of the Tualatin River that runs through the cities of Portland, Beaverton, Tigard, and Durham in northwestern Oregon. The land surrounding the creek includes residential, commercial, and industrial properties as well …

A Prdm16-Driven Signal Regulates Body Composition In Testosterone-Treated Hypogonadal Men, Siresha Bathina, Georgia Colleluori, Dennis T Villareal, Lina Aguirre, Rui Chen, Reina Armamento-Villareal

Faculty, Staff and Students Publications

BACKGROUND: Testosterone (T) therapy increases lean mass and reduces total body and truncal fat mass in hypogonadal men. However, the underlying molecular mechanisms for the reciprocal changes in fat and lean mass in humans are not entirely clear.

METHODS: Secondary analysis of specimens obtained from a single-arm, open-label clinical trial on pharmacogenetics of response to T therapy in men with late-onset hypogonadism, conducted between 2011 and 2016 involving 105 men (40-74 years old), who were given intramuscular T cypionate 200 mg every 2 weeks for 18 months. Subcutaneous fat (SCF), peripheral blood mononuclear cells (PBMC) and serum were obtained from …

A Comprehensive Meta-Analysis Of Tissue Resident Memory T Cells And Their Roles In Shaping Immune Microenvironment And Patient Prognosis In Non-Small Cell Lung Cancer, Aidan Shen, Aliesha Garrett, Cheng-Chi Chao, Dongliang Liu, Chao Cheng, Zhaohui Wang, Chen Qian, Yangzhi Zhu, Junhua Mai, Chongming Jiang

Faculty, Staff and Students Publications

Tissue-resident memory T cells (TRM) are a specialized subset of long-lived memory T cells that reside in peripheral tissues. However, the impact of TRM-related immunosurveillance on the tumor-immune microenvironment (TIME) and tumor progression across various non-small-cell lung cancer (NSCLC) patient populations is yet to be elucidated. Our comprehensive analysis of multiple independent single-cell and bulk RNA-seq datasets of patient NSCLC samples generated reliable, unique TRM signatures, through which we inferred the abundance of TRM in NSCLC. We discovered that TRM abundance is consistently positively correlated with CD4+ T helper 1 cells, M1 macrophages, and resting dendritic cells in the TIME. …

High Prevalence Of A-Β+ Ketosis-Prone Diabetes In Children With Type 2 Diabetes And Diabetic Ketoacidosis At Diagnosis: Evidence From The Rare And Atypical Diabetes Network (Radiant), Elizabeth Kubota-Mishra, Xiaofan Huang, Charles G Minard, Marcela Astudillo, Ahmad Refaey, Graciela Montes, Stephanie Sisley, Nalini Ram, William E Winter, Rochelle N Naylor, Ashok Balasubramanyam, Maria J Redondo, Mustafa Tosur, Radiant Study Group

Faculty, Staff and Students Publications

BACKGROUND:A−β+ ketosis-prone diabetes (KPD) in adults is characterized by presentation with diabetic ketoacidosis (DKA), negative islet autoantibodies, and preserved β-cell function in persons with a phenotype of obesity-associated type 2 diabetes (T2D). The prevalence of KPD has not been evaluated in children. We investigated children with DKA at “T2D” onset and determined the prevalence and characteristics of pediatric A−β+ KPD within this cohort.

METHODS: We reviewed the records of 716 children with T2D at a large academic hospital and compared clinical characteristics of those with and without DKA at onset. In the …

Development, Implementation, And Evaluation Of Three Outreach Events To Improve Covid-19 Vaccine Uptake Among Racial And Ethnic Minority Communities In Houston, Texas, 2022, Carmin Munoz-Lavanderos, Abiodun Oluyomi, Omar Rosales, Norvin Hernandez, Nana Mensah-Bonsu, Hoda Badr

Faculty, Staff and Students Publications

OBJECTIVES: Lack of access to timely, accurate, and linguistically appropriate COVID-19 information has complicated the dissemination of evidence-based information and contributed to vaccine hesitancy among racial and ethnic minority groups in the United States. We developed community events that provided outreach, education, and access to COVID-19 vaccination to overcome vaccine hesitancy in these communities.

METHODS: Using spatial analysis techniques, we identified 3 communities with low vaccine uptake in Houston, Texas, in fall 2021; engaged 20 stakeholders from these communities via 4 focus groups to understand barriers to vaccination; and developed and implemented 3 COVID-19 vaccine education and outreach events tailored …

Dna Mismatch Repair Defect And Intratumor Heterogeneous Deficiency Differently Impact Immune Responses In Diffuse Large B-Cell Lymphoma, Zijun Y Xu-Monette, Cancan Luo, Li Yu, Yong Li, Govind Bhagat, Alexandar Tzankov, Carlo Visco, Xiangshan Fan, Karen Dybkaer, Ali Sakhdari, Nicholas T Wang, Alyssa F Yuan, April Chiu, Wayne Tam, Youli Zu, Eric D Hsi, Anamarija M Perry, Wenting Song, Dennis O'Malley, Qingyan Au, Harry Nunns, Heounjeong Go, Michael B Møller, Benjamin M Parsons, Santiago Montes-Moreno, Maurilio Ponzoni, Andrés J M Ferreri, Aliyah R Sohani, Jeremy S Abramson, Bing Xu, Ken H Young

Faculty, Staff and Students Publications

Deficient (d) DNA mismatch repair (MMR) is a biomarker predictive of better response to PD-1 blockade immunotherapy in solid tumors. dMMR can be caused by mutations in MMR genes or by protein inactivation, which can be detected by sequencing and immunohistochemistry, respectively. To investigate the role of dMMR in diffuse large B-cell lymphoma (DLBCL), MMR gene mutations and expression of MSH6, MSH2, MLH1, and PMS2 proteins were evaluated by targeted next-generation sequencing and immunohistochemistry in a large cohort of DLBCL patients treated with standard chemoimmunotherapy, and correlated with the tumor immune microenvironment characteristics quantified by fluorescent multiplex immunohistochemistry and gene-expression …

Rragd-Associated Autosomal Dominant Kidney Hypomagnesemia With Cardiomyopathy: A Review On The Clinical Manifestations And Therapeutic Options, Francesco Trepiccione, Irene Sambri, Barbara Ruggiero, Francesco Emma, Andrea Ballabio, Giulia Florio, Ines Vanderheyden, Anna Iervolino, François Jouret

Duncan NRI Faculty and Staff Publications

Background: A hereditary condition primarily affecting the kidneys and heart has newly been identified: the RRAGD-associated autosomal dominant kidney hypomagnesemia with cardiomyopathy (ADKH-RRAGD). This disorder is characterized by renal loss of magnesium and potassium, coupled with varying degrees of cardiac dysfunction. These range from arrhythmias to severe dilated cardiomyopathy, which may require heart transplantation. Mutations associated with RRAGD significantly disrupt the non-canonical branch of the mechanistic target of rapamycin complex 1 pathway. This disruption hinders the nuclear translocation and transcriptional activity of the transcription factor EB a crucial regulator of lysosomal and autophagic function.

Summary: All identified RRAGD variants compromise …

Racial And Ethnic Disparities In Acuity Of Presentation Among Children With Newly Diagnosed Acute Leukemia, Lena E Winestone, Kelly D Getz, Yimei Li, Evanette Burrows, Michael E Scheurer, Vicky Tam, M Monica Gramatges, Jennifer J Wilkes, Tamara P Miller, Alix E Seif, Karen R Rabin, Brian T Fisher, Richard Aplenc

Center for Medical Ethics and Health Policy Staff Publications

We evaluated disparities in disease burden, organ dysfunction, vital signs, and timing of therapy in children newly presenting with acute leukemia. Among 899 patients with acute leukemia diagnosed at two large children's hospitals, a priori lab-based definitions of high disease burden, infection risk, renal dysfunction, and coagulopathy were applied to electronic health record data. Black patients with acute myeloid leukemia had increased prevalence of elevated white blood cell count and uric acid; Black patients with acute lymphoblastic leukemia demonstrated increased prevalence of coagulopathy. Black patients' presentation more frequently included multiple lab abnormalities consistent with advanced physiologic dysfunction. No differences were …

Bridging The Gap: Assessing Cmv Dnaemia In Kidney Transplant Recipients With Previous Solid Organ Transplants, Goni Katz-Greenberg, Julie M Steinbrink, Krishna Shah, Jennifer S Byrns

Faculty, Staff and Students Publications

Cytomegalovirus (CMV) infection poses a significant threat to solid organ transplant (SOT) recipients and can lead to various complications and adverse outcomes. In an effort to prevent CMV infection, it is common to utilize prophylactic strategies, including antiviral medications such as valganciclovir, especially for high-risk patients. Risk factors for CMV infection in kidney transplant recipients (KTRs) include CMV mismatch between donor and recipient (i.e., donor positive, recipient negative), and intensity of immunosuppression, such as the use of T-cell depleting agents. However, little attention has been given to KTRs with a history of prior SOTs, despite their prolonged exposure to immunosuppressive …

Leveraging Social Media For Recruiting Community Preceptors In Medical Education, Kamna Bansal, Shruti Varadarajan

Faculty, Staff and Students Publications

No abstract provided.

A Comprehensive Analysis Of Neuroblastoma Incidence, Survival, And Racial And Ethnic Disparities From 2001 To 2019, Kevin Campbell, David A Siegel, Puja J Umaretiya, Shifan Dai, Andras Heczey, Philip J Lupo, Jeremy M Schraw, Trevor D Thompson, Michael E Scheurer, Jennifer H Foster

Faculty, Staff and Students Publications

BACKGROUND: We characterize the incidence and 5-year survival of children and adolescents with neuroblastoma stratified by demographic and clinical factors based on the comprehensive data from United States Cancer Statistics (USCS) and the National Program of Cancer Registries (NPCR).

METHODS: We analyzed the incidence of neuroblastoma from USCS (2003-2019) and survival data from NPCR (2001-2018) for patients less than 20 years old. Incidence trends were calculated by average annual percent change (AAPC) using joinpoint regression. Differences in relative survival were estimated comparing non-overlapping confidence intervals (CI).

RESULTS: We identified 11,543 primary neuroblastoma cases in USCS. Age-adjusted incidence was 8.3 per …

Statins And The Risk Of Pancreatic Cancer: A Systematic Review And Meta-Analysis Of 2,797,186 Patients, Eryka Karbowska, Damian Swieczkowski, Aleksandra Gasecka, Michal Pruc, Kamil Safiejko, Jerzy R Ladny, Tomasz Kopiec, Milosz J Jaguszewski, Krzysztof J Filipiak, Zubaid Rafique, Lukasz Szarpak

Faculty, Staff and Students Publications

BACKGROUND: Statin use in many studies is related to the improvement of a patients' condition including reducing the risk of various malignancies. Herein, is a systematic review and meta-analysis to examine the evidence on the association between statin therapy and the risk of the occurrence of pancreatic cancer, mainly in terms of decreased risk of developing pancreatic cancer among patients using statin therapy in the long-term perspective.

METHODS: PubMed, Web of Science, Scopus and Cochrane Central Register of Controlled Trials (CENTRAL) were searched from database inception to December 1st, 2021. Random effect models were used to estimate summary odds ratios …

Lack Of Knowledge Of Antibiotic Risks Contributes To Primary Care Patients' Expectations Of Antibiotics For Common Symptoms, Lindsey A Laytner, Barbara W Trautner, Susan Nash, Roger Zoorob, Jennifer O Okoh, Eva Amenta, Kiara Olmeda, Juanita Salinas, Michael K Paasche-Orlow, Larissa Grigoryan

Faculty, Staff and Students Publications

Patient expectations of receiving antibiotics for common symptoms can trigger unnecessary use. We conducted a survey (n = 564) between January 2020 to June 2021 in public and private primary care clinics in Texas to study the prevalence and predictors of patients' antibiotic expectations for common symptoms/illnesses. We surveyed Black patients (33%) and Hispanic/Latine patients (47%), and over 93% expected to receive an antibiotic for at least 1 of the 5 pre-defined symptoms/illnesses. Public clinic patients were nearly twice as likely to expect antibiotics for sore throat, diarrhea, and cold/flu than private clinic patients. Lack of knowledge of potential risks …

Treatment Guidelines For Hyponatremia: Stay The Course, Richard H Sterns, Helbert Rondon-Berrios, Horacio J Adrogué, Tomas Berl, Volker Burst, David M Cohen, Mirjam Christ-Crain, Martin Cuesta, Guy Decaux, Michael Emmett, Aoife Garrahy, Fabrice Gankam-Kengne, John K Hix, Ewout J Hoorn, Kamel S Kamel, Nicolaos E Madias, Alessandro Peri, Julie Refardt, Mitchell H Rosner, Mark Sherlock, Stephen M Silver, Alain Soupart, Chris J Thompson, Joseph G Verbalis

Faculty, Staff and Students Publications

International guidelines designed to minimize the risk of complications that can occur when correcting severe hyponatremia have been widely accepted for a decade. On the basis of the results of a recent large retrospective study of patients hospitalized with hyponatremia, it has been suggested that hyponatremia guidelines have gone too far in limiting the rate of rise of the serum sodium concentration; the need for therapeutic caution and frequent monitoring of the serum sodium concentration has been questioned. These assertions are reminiscent of a controversy that began many years ago. After reviewing the history of that controversy, the evidence supporting …

Situations Predisposing Primary Care Patients To Use Antibiotics Without A Prescription In The United States, Lindsey A Laytner, Barbara W Trautner, Susan Nash, Fabrizia Faustinella, Roger Zoorob, Kiara Olmeda, Michael K Paasche-Orlow, Larissa Grigoryan

Faculty, Staff and Students Publications

BACKGROUND: Patients' situations can impact their intentions to use antibiotics without medical guidance (non-prescription use) in the future. This survey determines the prevalence of intended (future) use of non-prescription antibiotics for 13 predefined situations and identifies the sociodemographic characteristics associated with intended use for these types of situations.

METHODS: Patient surveys (N = 564) were conducted from January 2020 to June 2021 in the waiting rooms of 6 safety-net primary care clinics and 2 emergency departments in a private healthcare system. We used principal component analysis to identify 3 situational summary factors: barriers to a doctor visit, accessibility of non-prescription …

Electronic Vapor Products: Alarming Trends In United States Adolescents, Charles H Hennekens, Adedamola Adele, Maria C Mejia, Robert S Levine, Panagiota Kitsantas

Faculty, Staff and Students Publications

Background: The use of electronic vapor products (EVPs) increases the risks of nicotine addiction, drug-seeking behavior, mood disorders, and avoidable premature morbidities and mortality. We explored temporal trends in EVP use among US adolescents.

Methods: We used data from the Youth Risk Behavior Survey for school grades 9 through 12 from 2015 (earliest available data) to 2021 (the most recently available data) from the US Centers for Disease Control and Prevention (n=57,006).

Results: Daily use of EVPs increased from 2.0% in 2015 to 7.2% in 2019, a greater than 3.5-fold increase. Although the percentage decreased to 5.0% in 2021, it …