Digital Commons Network^™

Understanding How Laypeople Perceive Sexual Harassment Claims From "Non-Typical" Claimants, Jennifer Mezzapelle

Electronic Theses & Dissertations (2024 - present)

Over the past four decades, scholars have generated a wealth of knowledge on the topic of sexual harassment. However, in much of this research, findings may have resulted from participants assuming that the target in question was a “typical” sexual harassment victim (i.e., a White, straight, cisgender woman who is traditionally feminine and conventionally attractive; Kaiser et al., 2022). As a result, the generalizability of this research is inherently limited, as it may not accurately reflect how sexual harassment is perceived when it is aimed at a person who does not possess the attributes typically associated with sexual harassment targets. …

Assessing Associations Between Emergency Room Visits For Respiratory And Cardiovascular Diseases And Criteria Air Pollutants Exposure In New York State, Tamba Solomon Lebbie

Electronic Theses & Dissertations (2024 - present)

Abstract

Air pollution is a major environmental health hazard for the general population. Approximately 90% of the global population is at risk of both indoor and outdoor air pollution, and it accounts for an estimated 7 million premature deaths every year according to the World Health Organization (WHO). Multiple studies including epidemiological and molecular analyses have confirmed the negative effects of air pollutants on human health even at levels within the WHO guidelines. This study examines the health impacts of releases of criteria air pollution from point sources in New York State (NYS). There is evidence from population studies that …

Remediating Fibrosis To Restore Salivary Gland Function, Jennifer Morrissey

Electronic Theses & Dissertations (2024 - present)

Fibrosis is defined by the overgrowth, hardening, and scarring of various tissues and is attributed to excess deposition of extracellular matrix components including collagen. In the case of persistent injury or autoimmunity, as in Sjogren’s Disease, the ECM persists. Fibrosis can be studied in multiple animal models. Our lab has published the use of a mouse submandibular salivary gland partial resection model. In this procedure 40% of the left distal tip of the submandibular salivary gland (SMG) is excised. This leads to a chronic sustained fibrotic response in a localized region. The use of the non-obese diabetic mouse (NOD) has …

Development And Initial Validation Of The Supervisor Responsiveness Scale, Ramon Garcia

Electronic Theses & Dissertations (2024 - present)

Theoretically, responsiveness to the emergent needs of supervisees and clients is the primary means by which clinical supervisors help trainees become effective psychotherapists (Friedlander, 2012). To advance understanding and research on this aspect of supervision, the Supervisory Responsiveness Scale (SRS) was developed and assessed psychometrically.

First, 35 items reflecting trainees’ perceptions of their supervisor’s responsiveness, as defined by Friedlander (2012), were developed and rated for clarity, face and content validity by a panel of 12 experienced supervisors. After the item pool was refined based on these ratings, 216 supervisees representing all training levels rated each item on a 1 ( …

Chemical Reduction Of Curved Molecular Nanographenes: Metal Intercalation And Core Transformation, Yikun Zhu

Electronic Theses & Dissertations (2024 - present)

The promising lithium storage capacity and fast charge transport rate make graphene a great candidate for energy storage applications. However, the harsh synthetic conditions lead to uneven size distribution and poor solubility, posing limitations on further applications and modifications of graphene and its derivatives. Molecular nanographenes, as graphene cutouts, possess outstanding chemical and physical properties stemming from their parent graphene but also demonstrate such unique features as controllable synthetic conditions, defined molecular structures, uniform size, and relatively good solubility. The improved solubility enables the use of solution chemistry methods for design modifications of molecular nanographenes and for systematical investigation of …

Predictive Analytics In Bronchopulmonary Dysplasia: Past, Present, And Future, Bryan G Mcomber, Alvaro G Moreira, Kelsey Kirkman, Sebastian Acosta, Craig Rusin, Binoy Shivanna

Faculty, Staff and Students Publications

Bronchopulmonary dysplasia (BPD) remains a significant complication of prematurity, impacting approximately 18,000 infants annually in the United States. Advances in neonatal care have not reduced BPD, and its management is challenged by the rising survival of extremely premature infants and the variability in clinical practices. Leveraging statistical and machine learning techniques, predictive analytics can enhance BPD management by utilizing large clinical datasets to predict individual patient outcomes. This review explores the foundations and applications of predictive analytics in the context of BPD, examining commonly used data sources, modeling techniques, and metrics for model evaluation. We also highlight bioinformatics' potential role …

Compassion Cartography: Mapping The Psychological Landscape Of Altruistic Equity And Effectiveness, Kyle Fiore Law

Electronic Theses & Dissertations (2024 - present)

Psychologists and philosophers have often championed deliberative reasoning over empathy as a better approach to overcoming parochial biases and guiding altruistic equity and effectiveness. Advocates of the effective altruism (EA) philosophy even advise philanthropists to downregulate empathic responses to maximize the impact of their donations. However, recent research reveals that extraordinary altruists (XAs), such as those who donate organs to strangers, are driven primarily by empathy. This dissertation explores whether empathy necessarily impedes altruistic equity (impartial regard for others’ welfare) and effectiveness (prioritizing impact), revealing a more nuanced reality that challenges this perspective. Across two phases of research involving three …

Evaluating The Impact Of Instruction Mode And Experience On Meditation Intentions And Outcomes In Self-Taught Meditators And Mindfulness-Based Stress Reduction Completers, Leah Howard

Electronic Theses & Dissertations (2024 - present)

Objectives: The widespread availability of mindfulness-based practices has led to growing concern about the potential for misuse, namely the use of such practices as a control-based strategy rather than in an acceptance-based manner consistent with research. Thus, the present study aimed to elucidate factors (e.g., mode of instruction, meditation experience, psychological [in]flexibility [PF/PI]) that may relate to intentions guiding meditation use. Methods: Self-taught (ST) and Mindfulness-Based Stress Reduction (MBSR) meditators (N = 122, Mage = 46.54, SDage = 16.49, 65.6% Female) completed a battery of measures assessing meditation intentions (control- or acceptance-based), meditation experience (in months), PF/PI, psychological distress, …

Implications Of 5-Methylcytosine (M5c) And N4-Actylcytidine (Ac4c) In Epithelial To Mesenchymal Transition (Emt) In Human Breast Cancer, Manuel A. Pazos Ii

Electronic Theses & Dissertations (2024 - present)

Breast cancer is a complex disease that continues to haunt women and their loved ones around the world. It is currently the leading cause of cancer-related mortality among women. While most breast cancer patients can catch the disease before progression, others are less fortunate. The prognosis of those whose disease has advanced to metastatic or invasive breast cancer (IBC) is grim. Metastasis occurs when cancer cells undergo epithelial to mesenchymal transition (EMT), migrate to distant body tissues, then form new tumors. It is imperative to better understand the process of EMT to develop superior ways to detect breast cancer before …

Examining The Effects Of Video Self-Modeling With Goal Setting On Third-Grade Students' Oral Reading Fluency, Sara Sleiman Tellaoui

Electronic Theses & Dissertations (2024 - present)

Video self-modeling (VSM) is an intervention based on Bandura’s (1999) theory of observational learning, which assumes that children learn a target behavior by observing a more competent model. VSM is assumed to provide an effective model from which children can learn given that the learner and model are the same person but differ only in their skills. More recently, studies have explored the effectiveness of VSM as an intervention for oral reading fluency (ORF) and showed promising results. Goal setting (GS) is another intervention that has been found to be effective in increasing students’ performance by motivating them to meet …

Building Engaged Audiences: The Influence Of Multimedia-Inclusive Posts On Online Engagement Breadth And Depth For Arts And Culture Nonprofit Organizations, Sabrina Jeffcoat

Electronic Theses & Dissertations (2024 - present)

In recent years, broad access to digital communication tools provided by the “tech boom” has forced arts and culture nonprofit organizations (ACNPO) to transition to social media and mobile applications to engage audiences. While various approaches focus on building breadth (i.e. recirculation of content) and depth (i.e. replies) of engagement, ACNPO use multimedia to spur discussion and dissemination of their mission. Dependent on individual donors who generally give in small amounts, ACNPO are reliant on effective and visual social media campaigns to drive virality and broaden marketing appeal. Yet questions remain whether the presence of multimedia-inclusive posts (MIP) generates broader …

Exploring The Epitranscriptomic Response To Senolytics And Senomorphs In Cellular Models Of Aging, Emily Benson

Electronic Theses & Dissertations (2024 - present)

In senescence that occurs with aging, cells stop dividing and initiate a pro-inflammatory program called the senescence associated secretory phenotype (SASP). SASP can lead to cell damage and has been linked to age-related conditions such as cancer, diabetes, osteoporosis, cardiovascular disease, Alzheimer’s disease, and osteoarthritis. The epitranscriptome regulates translation through post-transcriptional RNA modifications and can control when and how much of protein synthesis occurs. Several tRNA modifications that include 5-methoxycarbonylmethyl (mcm⁵U), 5-methoxycarbonylmethyl-2-thiouridine (mcm⁵s²U), and mcm⁵Um (5-methoxycarbonylmethyl-2′-O-methyluridine) are linked to the translation of enzymes involved in the detoxification of reactive oxygen species (ROS), …

Molecular-Level Design Of Heterometallic Precursors For Rechargeable Battery Cathode Materials, Yuxuan Zhang

Electronic Theses & Dissertations (2024 - present)

The synthetic methods for rechargeable battery cathodes are rapidly evolving along with the continuous advancement of the materials themselves. Utilizing precursors for the synthesis of Li- and Na-ion cathode materials are known to ensure a phase-pure product with isotropic element distribution, thereby further enhancing the electrochemical properties of the cathode material. As more cathode materials with complex compositions continue to emerge, the strategies for designing the corresponding precursors are also getting diversified. One of the most promising directions is the employment of single-source precursors (SSPs), defined as molecules that contain all necessary elements in the proper ratio and decomposable under …

Assessment Of Spatial Distribution Patterns And Infestation Risk Over Time Of Spotted Lanterfly (Lycorma Delicatula) In New York State, Alanna Richman

Electronic Theses & Dissertations (2024 - present)

Spotted Lanternfly (Lycorma delicatula) is an invasive treehopper native to Asia. It was first introduced to Pennsylvania in 2014, and as of 2020 it has expanded to New York state. Their preferred host tree is the invasive tree of heaven (Ailanthus altissima), but they will feed on over 173 different plants worldwide. Preferred host species in New York state include agricultural vegetation such as grape vines and fruit trees. Positive Spotted Lanternfly site data collected by the New York Department of Agriculture and Markets and iMapInvasives were analyzed using ArcGIS Pro to assess spatial distribution patterns. …

Innovative Solutions In Medical Diagnostics, Seafood Industry, Environmental, And Forensic Applications Through Integrating Raman Spectroscopy And Machine Learning, Luis Perez Almodovar

Electronic Theses & Dissertations (2024 - present)

There is an urgent need for rapid and on-site analytical methods to address various environmental and forensic challenges. This dissertation explores the application of Raman spectroscopy combined with machine learning for three critical areas: evaluating perfluoroalkyl or polyfluoroalkyl substances (PFAS) exposure in wildlife, authenticating tuna species in the seafood industry, identifying body fluids at crime scenes, and medical diagnostics.

First, Raman spectroscopy and support vector machine discriminant analysis (SVMDA) were employed to detect PFAS levels in the blood plasma of smallmouth bass from two different tributaries, rivers, or streams that flow into larger bodies of water. The method achieved 100% …

Leveraging Redundancy As A Link Between Spreading Dynamics On And Of Networks, Felipe Xavier Costa

Electronic Theses & Dissertations (2024 - present)

A constant quest in network science has been in the development of methods to identify the most relevant components in a dynamical system solely via the interaction structure amongst its subsystems. This information allows the development of control and intervention strategies in biochemical signaling and epidemic spreading. We highlight the relevant components in heterogeneous dynamical system by their patterns of redundancy, which can connect how dynamics affect network topology and which pathways are necessary to spreading phenomena on networks. In order to measure the redundancies in a large class of empirical systems, we develop the backbone of directed networks methodology, …

A Descriptive Analysis Of Depressive Symptoms And Body Image By Race/Ethnicity And Nativity Status Among Adolescents, Radhika Prasad

Electronic Theses & Dissertations (2024 - present)

Previous research on the immigrant health paradox among children and adolescents show a mental health advantage yet it is unclear if this applies in a similar magnitude to females (Fillion et al., 2018; Zarei et al., 2023). Immigrants may be exposed to stressors related to immigration and acculturation. Some research suggests that females respond more to stress through internalizing symptoms relative to males (Hall-Lande et al., 2007; Adkins et al., 2009). Given these gender differences in stress response, female immigrants may be particularly vulnerable to the psychological consequences of immigration related stressors. The immigrant health paradox has also overlooked subjective …

The Role Of Familial Support And Gender In Asian American Students’ Stem Career Development: A Test Of Social Cognitive Career Theory, Xiao Ting Wang

Electronic Theses & Dissertations (2024 - present)

This study, based on Social Cognitive Career Theory (SCCT; Lent et al., 1994, 2000), investigated the role of familial support in the STEM career development of Asian American college students. Participants included 446 first-year undergraduate students who identified as Asian or Asian American and had not declared an academic major. Due to multicollinearity, four initial familial support variables—instrumental assistance, career-related modeling, verbal encouragement, and emotional support—were regrouped into two: performance motivation (instrumental assistance and verbal encouragement) and career mentoring (career-related modeling and emotional support). Structural equation modeling showed acceptable fit for a modified model, and the results partially supported the …

"Not Trans Enough": A Qualitative Inquiry Of Non-Binary Individuals' Experiences Of Transphobia Within The Lgbtq+ Community, Alyssa Lombardi

Electronic Theses & Dissertations (2024 - present)

Transphobia has been well-documented to have detrimental impacts on the lives of transgender individuals. However, research typically has not focused on the experience of non-binary individuals, and particularly even less so on their experiences of within-group discrimination. This study used Interpretative Phenomenological Analysis to understand both the experience and expression of transphobia toward non-binary people from within the LGBTQ+ community. Twelve interviews were conducted with six non-binary individuals ranging in age from 23 to 33. Each interview was analyzed and coded, resulting in four superordinate themes: The Experience of Enbyphobia, The Impact of Enbyphobia, The Expression of Enbyphobia, and The …

The Study Of Ribosome-Amplified Metabolism, Rambo, Effect In Vitro And In Live Cells, Jianchao Yu

Electronic Theses & Dissertations (2024 - present)

Quinary interactions arise due to the extreme macromolecular crowding inside live cells. Quinary interactions affect intracellular protein stability, activity, and homeostasis. Ribosomes, traditionally known for their role in protein synthesis, have been found to engage in quinary interactions with metabolic enzymes, modulating their activity and thereby revealing a potential regulatory role for ribosomes in cellular metabolism. This phenomenon, termed the Ribosome-Amplified MetaBOlism (RAMBO) effect, was investigated in this dissertation through a series of in vitro and in vivo studies using primarily Nuclear Magnetic Resonance (NMR) spectroscopy.

Firstly, an NMR-based direct enzyme assay compatible with ribosome was developed and validated using …

Developing Cellular Systems To Elucidate Rna Structural Dynamics Of Cag Expansion Transcripts In Spinocerebellar Ataxias, Victoria Demeo

Electronic Theses & Dissertations (2024 - present)

Spinocerebellar ataxias (SCAs) are a diverse group of over 40 genetically heterogeneous neurodegenerative disorders, many of which are caused by a trinucleotide CAG repeat expansion in the coding region of specific genes. These expansions lead to the production of polyglutamine (polyQ) tracts that interfere with normal protein function, triggering cellular dysfunction and contributing to disease pathogenesis. The most well-known of these SCAs, such as SCA1, SCA2, and SCA3, exhibit progressive neurodegeneration, yet the precise mechanisms through which these mutations cause disease remain poorly understood.

A significant challenge in studying CAG repeat expansion disorders lies in the complexity of the disease …

The Exceptionalist-Normalist Continuum: Contents, Correlates, And Consequences Of Beliefs About The Psychological (A)Typicality Of Perpetrators Of Mass Atrocities, Dylan Campbell

Electronic Theses & Dissertations (2024 - present)

A consensus view within the literature on perpetrator behavior in mass atrocities holds that perpetrators tend to be psychologically typical rather than atypical and thus, that even “ordinary” people are capable of extreme acts of violence against civilians when the right combination of social-psychological forces is at work. Whereas much prior research speaks in some way to this claim’s validity, no prior study of which I am aware has directly investigated laypeople’s beliefs regarding the truth of this proposition. Here, I report findings from four preregistered studies (total N = 1,256) investigating the contents, correlates, and consequences of lay theories …

Informational Principles And Structures In Quantum Theory, Yang Yu

Electronic Theses & Dissertations (2024 - present)

This thesis examines the concept of information within the realm of quantum physics, investigating the nuanced relationship between information and physical laws as applied to quantum systems. With no consensus on a single definition of information in the physical sciences, our exploration is partitioned into two significant studies, each addressing distinct aspects of information in quantum contexts.

In the first study, we concentrate on the information that can be obtained from measurement results on identical quantum systems. The traditional approach of using Shannon entropy is limited due to its applicability primarily to discrete probability distributions. By incorporating a Bayesian update …

Stabilizing Bulk Lead-Free Tin Halide Perovskites, William Rice

Electronic Theses & Dissertations (2024 - present)

Tin halide perovskites are a growing candidate in the semiconducting materials field due to their band gap, and ability to be doped (specifically p-type doped). Halide perovskites are sensitive to light and air which causes the degradation of the material from its preferred cubic perovskite lattice. This thesis introduces a way of stabilizing bulk CsSnCl3 through the Goldschmidt tolerance factor. It will also introduce potential new ways to p-type dope halide perovskites. We attempted to p-type dope our halide perovskite by substitutional, interstitial, and vacancy doping to increase the carrier concentration to compete with current perovskites. During our trials of …

Advancements In Forensic Analysis: Development Of Mass Spectrometric And Chemometric Approaches For The Identification Of Synthetic New Psychoactive Substances And Plant Materials, Mónica Ventura

Electronic Theses & Dissertations (2024 - present)

While forensic science is a well-established discipline, a number of federal agencies have highlighted challenges that continue to plague the field and the extent to which these challenges remain unaddressed. Examples are the illegal trade of wildlife timber and the drug epidemic. Characterization of these materials requires nuanced method development for compound determination, matrix material-specific protocols, and heavy use of expensive consumables. The application of a technique such as direct analysis in real time – high-resolution mass spectrometry (DART-HRMS) provides the opportunity to circumvent many of the challenges presented by conventional methods. In general, little to no sample preparation is …

Studies In Three-Component Modification Of Lysine, Investigating Reversible Potential Of An Intricate Bicyclo [3.3.1] Nonane Scaffold, Ryan Bartlett

Electronic Theses & Dissertations (2024 - present)

Synthesis of small-molecule conjugates capable of selective attachment to a peptide/protein backbone paves way for new therapeutic applications of protein modification. Sufficient inhibition or installation of function requires extensive design so the compound may identify and attach to the intended site. The utility of such an approach has prompted a number of applicable strategies and has rendered the development of new modification scaffolds less necessary. On the other hand, covalent modification to the biologics with ability to remove the conjugate via stimulus is underdeveloped, amplifying a current need to investigate the reversible potential for conjugation and deconjugation techniques in regard …

“A True Tower Of Babel”: Nation, Race, And Gender In The French Foreign Legion, 1831 To 1854, Nicholas Michael Charnley

Electronic Theses & Dissertations (2024 - present)

The French Foreign Legion, part of the July Monarchy’s 1831 expansion of the Army of Africa, sought to create a non-French force entirely deployable outside of the metropole. The creation of the expatriate corps intended to solve two of France’s most pressing problems at the time: an excess of foreign migrants at home, and a dearth of French soldiers abroad. The Paris government hoped to attract recruits from its considerable non-national male population, particularly political exiles and migrant workers fleeing Europe’s 1830 revolutionary wave. Initially intended as a temporary expedient for the homeland’s demographic crisis, the expatriate fighting force grew …

Evaluation Of The Physicochemical Properties And Soil Biogeochemistry Of Fire Residues, Lingqun Zeng

Electronic Theses & Dissertations (2024 - present)

Wildland fire is a main driving force in the Earth system and affects ecosystem properties and processes across spatio-temporal scales. The burning of biomass and production of solid fire residues (conventionally termed fire ash) that are a mixture of completely and incompletely burned materials (inorganic ash and pyrogenic carbon), represent the direct and prominent changes by fires. Cycling of the fire residues is an integral component of elemental cycles and can mediate other biogeochemical processes.

This dissertation aims to fill important knowledge gaps in understanding the disturbance of wildland fires to biogeochemical processes in soils. First, this work characterized and …

Factors That Influence Clinicians' Intention To Use A Trauma-Informed Approach To Care In Women's Substance Use Disorder Treatment, Lauren Cestone

Electronic Theses & Dissertations (2024 - present)

Aims: Regardless of literature citing the effectiveness of trauma-informed care (TIC) (e.g., Capezza & Najavits, 2012; Covington, 2008; Morgan et al., 2020), implementation is lacking in settings that serve women with substance use disorders (SUD) (Bartholow & Huffman, 2023; Capezza & Najavits, 2012; Terplan et al., 2015). Not implementing TIC often results in methods that are trauma-inducing, may prevent the achievement desired outcomes, and lead to negative outcomes such as drop-out and relapse (Brown et al., 2013; Capezza & Najavits, 2012; Claus & Kindleberger, 2002; Hales et al., 2019; SAMHSA, 2014). This study aims to provide a theoretically driven empirical …

Androgen Regulation Of The Hpa Axis And Stress-Related Behaviors In Mice: The Role Of Crf And Crf Receptor 1, Krystyna Ann Rybka

Electronic Theses & Dissertations (2024 - present)

Mood disorders such as anxiety and depression are nearly twice as prevalent in women when compared to men, with potential contributing factors involving sex-dependent exposure to gonadal hormones and dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. Androgen actions through androgen receptors (AR) or actions at estrogen receptors such as ERα, following the conversion of androgens to estradiol, have been shown to regulate stress-related behaviors as well as HPA axis responsiveness. Where androgen actions at AR appear to decrease the stress response and subsequent stress-related behaviors, actions at ERα seem to do the opposite and increase HPA axis reactivity. When the HPA …