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Gvsu Undergraduate And Graduate Catalog, 2024-2025, Grand Valley State University Jan 2024

Gvsu Undergraduate And Graduate Catalog, 2024-2025, Grand Valley State University

Course Catalogs, 1963 - Current

Grand Valley State University 2024-2025 undergraduate and graduate course catalog. Course catalogs are published annually to provide students with information and guidance for enrollment.


Distribution: Understanding Customer-Facing Logistics In Africa, Emmanuel T. Kodzi Jan 2024

Distribution: Understanding Customer-Facing Logistics In Africa, Emmanuel T. Kodzi

Faculty Publications

Companies seeking to do business in Africa often focus more on challenges they need to address, rather than opportunities presented to them. The need to manage their investments across diverse countries, population profiles, infrastructure development levels, and local capabilities is viewed in terms of complexity. However, improved situational understanding will better inform investment decisions regarding product movements among points of origin, production, and consumption. Several aspects of logistics may be considered in this regard, but we focus on customer-facing logistics. We assume that few companies have the capability and resources to both produce and deliver products to end-buyers in a …


Unjust And Unsafe: The Eviction Experiences Of Latine Immigrant And Farmworker Tenants In Oregon, Natalie J. Cholula, Lisa K. Bates, Alex Farrington, Marisa Zapata, Jacen Greene, Azad Amir-Ghassemi, Colleen Carroll Jan 2024

Unjust And Unsafe: The Eviction Experiences Of Latine Immigrant And Farmworker Tenants In Oregon, Natalie J. Cholula, Lisa K. Bates, Alex Farrington, Marisa Zapata, Jacen Greene, Azad Amir-Ghassemi, Colleen Carroll

Sociology Faculty Publications and Presentations

Latine immigrant households often face housing instability due to language barriers, immigration status, and limited access to government resources. Oregon farmworkers experience additional obstacles to safe and stable housing caused by low wages, a lack of affordable housing options, and social isolation. In light of the identified needs and lack of equitable access to resources that this group experiences, the Evicted in Oregon research team conducted focus groups with Latine immigrant and farmworker tenants in Multnomah, Washington, and Marion Counties. The aim was to gain insight into their experiences with eviction and understand how they navigated through evictions during the …


Evidence That Ericoid Mycorrhizal Shrubs Can Outcompete Ectomycorrhizal Trees For Nitrogen In Tannin-Rich Litter, Kai C. Rains, Caroline Bledsoe, Tamara E. Kraus, Nina Wurzburger Jan 2024

Evidence That Ericoid Mycorrhizal Shrubs Can Outcompete Ectomycorrhizal Trees For Nitrogen In Tannin-Rich Litter, Kai C. Rains, Caroline Bledsoe, Tamara E. Kraus, Nina Wurzburger

School of Geosciences Faculty and Staff Publications

Mycorrhizal associations of trees play a key role in ecosystem biogeochemistry, yet we know relatively little about the nutrient acquisition strategies of ericoid mycorrhizal (ErM) shrubs, despite their prevalence in forest understories. ErM shrubs tend to produce litter with high concentrations of polyphenols, which form decay-resistant complexes with organic nitrogen (N). Some ErM fungi appear capable of producing a diverse suite of extracellular enzymes, but it is unclear whether this enables ErM shrubs to acquire the N from their own litter, and whether this ability is greater than that of ectomycorrhizal (EcM) trees, with which they commonly co-occur. Here, we …


Uav-Based Wetland Monitoring: Multispectral And Lidar Fusion With Random Forest Classification, Robert Van Alphen, Kai C. Rains, Mel Rodgers, Rocco Malservisi, Timothy H. Dixon Jan 2024

Uav-Based Wetland Monitoring: Multispectral And Lidar Fusion With Random Forest Classification, Robert Van Alphen, Kai C. Rains, Mel Rodgers, Rocco Malservisi, Timothy H. Dixon

School of Geosciences Faculty and Staff Publications

As sea levels rise and temperatures increase, vegetation communities in tropical and sub-tropical coastal areas will be stressed; some will migrate northward and inland. The transition from coastal marshes and scrub–shrubs to woody mangroves is a fundamental change to coastal community structure and species composition. However, this transition will likely be episodic, complicating monitoring efforts, as mangrove advances are countered by dieback from increasingly impactful storms. Coastal habitat monitoring has traditionally been conducted through satellite and ground-based surveys. Here we investigate the use of UAV-LiDAR (unoccupied aerial vehicle–light detection and ranging) and multispectral photogrammetry to study a Florida coastal wetland. …


Winter 2024: Amplifying Jan 2024

Winter 2024: Amplifying

The Weldon Times

A student-run publication from the Schulich School of Law at Dalhousie University.

Co-Editors in Chief: Nicole Payette, Elyse Loewen


Country Women's Council, Usa Records - Accession 659, Country Women's Council, Usa Jan 2024

Country Women's Council, Usa Records - Accession 659, Country Women's Council, Usa

Manuscript Collection

The Country Women’s Council, USA Records consists of records related and produced by the organization. The records include meeting minutes, correspondence, publications, newspaper clippings, credentials, reports, proposed budgets, financial information, voting records, and other items related to the council’s business and activities. This collection is a good source of rural women’s activities during the mid to late twentieth century.


American Association Of Retired Persons: Catawba Chapter Records - Accession 745, American Association Of Retired Persons: Catawba Chapter Jan 2024

American Association Of Retired Persons: Catawba Chapter Records - Accession 745, American Association Of Retired Persons: Catawba Chapter

Manuscript Collection

The American Association of Retired Persons- Catawba Chapter Records consist of material related to Rock Hill, SC based chapter (#1416) which was founded on October 15, 1973. The American Association of Retired Persons (AARP) advocates for Americans 50 or older on many health and fiscal issues at the federal, state and local level. The collection consists of by-laws and a certificate of incorporation and award, Activities and Chapter evaluations reports, correspondence papers, financial papers, membership lists and rolls, and newspaper article clippings, documenting the history, development and activities of the AARP.


Ruth Harvey Thomason Papers - Accession 739, Ruth Harvey Thomason Jan 2024

Ruth Harvey Thomason Papers - Accession 739, Ruth Harvey Thomason

Manuscript Collection

The Ruth Harvey Thomason Papers consists of materials collected by Ruth Harvey Thomason Turner (1913-1984) was a 1929 graduate of Winthrop Training School and a 1933 graduate of Winthrop College. Ruth Harvey Thomason was the daughter of Winthrop professor, Dr. John Furman Thomason (1878-1967) who was a Professor of Rural Education from 1918-1943. The collection consists of materials she collected while she attended the Winthrop Training School (1925-1929) and Winthrop College (1929-1933). The collection consists of scrapbooks, personal correspondence, photographs, newspaper clippings, programs, mementos, and memorabilia. This collection is an excellent snapshot of student and Winthrop life during the 1920s …


Nsu Florida Undergraduate Student Catalog 2024-2025, Nova Southeastern University Jan 2024

Nsu Florida Undergraduate Student Catalog 2024-2025, Nova Southeastern University

Undergraduate Programs Course Catalogs

No abstract provided.


Diversity Across Disciplines: Student Response To Dei Content In College Curricula, Angela Pettitt Jan 2024

Diversity Across Disciplines: Student Response To Dei Content In College Curricula, Angela Pettitt

Theses and Dissertations

Discussion and inclusion of diversity-related topics in higher education are often confined to specific courses designated as fulfilling a university-mandated diversity requirement such as courses in women's studies, Black history or literature, Eastern religions, among others. Mainstream general education courses in disciplines such as psychology, chemistry, or communications typically do not address diversity, equity, and inclusion (DEI) topics as part of the curriculum, even if individual textbooks, courses, or faculty work to improve such courses' pluralism. However, as the U.S. population becomes both more diverse and segregated, and as DEI initiatives come under fire from state legislators, students receive conflicting …


The Lord Will Provide: What Will You Do?, Steve Case Jan 2024

The Lord Will Provide: What Will You Do?, Steve Case

Journal of Adventist Youth and Young Adult Ministries

Youth ministry often rises or falls based on its leadership. However, recruiting, training, and retaining youth leaders remains problematic. Making youth leadership development the modus operandi of youth ministry turns it into an ongoing process rather than an annual tug-of-war. It includes the youth as leaders, as well as a variety of other ages. It goes beyond completing a task, although it includes many tasks. And the expectation is to engage and explore one’s own development as well as that of the group. Resources exist to foster this, but the buy-in has been limited. Following these recommendations could result in …


Educators Remedying Linguicism Through Critical Language Awareness And Critical Trans/Multilingualism: Towards Planetary Justice, Kate Alice Garnett Jan 2024

Educators Remedying Linguicism Through Critical Language Awareness And Critical Trans/Multilingualism: Towards Planetary Justice, Kate Alice Garnett

Antioch University Dissertations & Theses

The aim of this dissertation is to investigate how a critical understanding of language use, language ideologies, and linguicism can influence educators’ praxis and identities. Specifically, the research explores how Critical Language Awareness (CLA) impacts educators’ praxis, their lingua-cultural identities, and their relationships with language and linguicism towards planetary justice. These inquiries were examined through participants’ involvement in a 6-week teacher educator course designed by this researcher entitled Humane Language Education. The course aimed to enable participants to analyze and address language injustices individually, communally, and globally. Unexamined language biases erode linguistic and cultural diversity, disseminate violence and discrimination, and …


The Anticipation Is Killing Me! - Examining The Mediating And Moderating Relationships Between Mistreatment Anticipation And Work Engagement, Mia N. Fagan Jan 2024

The Anticipation Is Killing Me! - Examining The Mediating And Moderating Relationships Between Mistreatment Anticipation And Work Engagement, Mia N. Fagan

Master's Theses

The mistreatment of workers by customers in the service industry is widespread and well-known. Although customer mistreatment is associated with negative consequences for employees, there is little knowledge about the potential consequences of the expectation of future mistreatment. The present study examined the relationship between mistreatment anticipation and work engagement and hypothesized that mistreatment anxiety would mediate the relationship between the two and that perceived organizational support (POS) would moderate the relationship between mistreatment anticipation and mistreatment anxiety. Data were collected from a sample of 183 individuals via an online survey. Results showed a significant and negative relationship between mistreatment …


Engineering Mussel Foot Protein 5 (Mfp5) For Enhanced Adhesive Performance In Tendon And Bone Repair, Ziyue Zhu Jan 2024

Engineering Mussel Foot Protein 5 (Mfp5) For Enhanced Adhesive Performance In Tendon And Bone Repair, Ziyue Zhu

McKelvey School of Engineering Graduate Student Theses & Dissertations

This study explores the development of Mussel Foot Protein 5 (MFP5) bioadhesives to improve tendon-to-tendon and tendon-to-bone adhesive outcomes. MFP5, known for its underwater adhesive properties, was synthesized using recombinant techniques and optimized through coacervation and cross-linking. Adhesion tests demonstrated the superior performance of the optimized MFP5 adhesive on the tendon and bone samples. Improved protein concentration testing and purification methods enhanced MFP5 yield and consistency. Future research will focus on further standardization, exploring alternative purification methods, and evaluating the adhesive's performance in animal models. This study lays a foundation for developing robust MFP5-based bioadhesives, potentially revolutionizing surgical repair techniques …


Late-Arriving Votes And Electoral Fraud: A Natural Experiment And Regression Discontinuity Evidence From Bolivia, Diego Escobari, Gary A. Hoover Jan 2024

Late-Arriving Votes And Electoral Fraud: A Natural Experiment And Regression Discontinuity Evidence From Bolivia, Diego Escobari, Gary A. Hoover

School of Economics and Finance Faculty Publications

This paper uses a unique data set and a natural experiment to test if electoral fraud can exist in late-arriving votes. On the night of the 2019 Bolivian elections, the official vote counting system that was expected to publish the results real-time, suddenly stopped. When it resumed, the results had flipped. We estimate several difference-in-differences specifications using a 2016 referendum and the votes of other political parties. We find that the extent of the fraud is 2.51% of the valid votes, sufficient to change the outcome of the election. Our results are robust to polling-station-level shocks common across 2019 and …


Department Of English Newsletter, Winter 2023-2024, Illinois State University, Department Of English Jan 2024

Department Of English Newsletter, Winter 2023-2024, Illinois State University, Department Of English

Department of English Newsletter

Newsletter of the Illinois State University Department of English


Corrigendum: High-Definition Transcranial Direct Current Stimulation For Upper Extremity Rehabilitation In Moderate-To-Severe Ischemic Stroke: A Pilot Study, Jordan N Williamson, Shirley A James, Dorothy He, Sheng Li, Evgeny V Sidorov, Yuan Yang Jan 2024

Corrigendum: High-Definition Transcranial Direct Current Stimulation For Upper Extremity Rehabilitation In Moderate-To-Severe Ischemic Stroke: A Pilot Study, Jordan N Williamson, Shirley A James, Dorothy He, Sheng Li, Evgeny V Sidorov, Yuan Yang

Faculty, Staff and Student Publications

No abstract provided.


The Kidney In Heart Failure: The Role Of Venous Congestion, Oluwaseun Adebayo Bamodu, Chen-Chih Chung, Thomas R Pisanic, Alexander T H Wu Jan 2024

The Kidney In Heart Failure: The Role Of Venous Congestion, Oluwaseun Adebayo Bamodu, Chen-Chih Chung, Thomas R Pisanic, Alexander T H Wu

Faculty, Staff and Student Publications

BACKGROUND: Cancer stem cells (CSCs) have emerged as pivotal players in tumorigenesis, disease progression, and resistance to therapies.

OBJECTIVE: This comprehensive review delves into the intricate relationship between CSCs and the cell-of-origin in diverse cancer types.

DESIGN: Comprehensive review of thematically-relevant literature.

METHODS: We explore the underlying molecular mechanisms that drive the conversion of normal cells into CSCs and the impact of the cell-of-origin on CSC properties, tumor initiation, and therapeutic responses. Moreover, we discuss potential therapeutic interventions targeting CSCs based on their distinct cell-of-origin characteristics.

RESULTS: Accruing evidence suggest that the cell-of-origin, the cell type from which the tumor …


Identifying Missing Is-A Relations In Snomed Ct With Fine-Tuned Pre-Trained Language Models And Non-Lattice Subgraphs, Xubing Hao, Rashmie Abeysinghe, Jay Shi, Guo-Qiang Zhang, Licong Cui Jan 2024

Identifying Missing Is-A Relations In Snomed Ct With Fine-Tuned Pre-Trained Language Models And Non-Lattice Subgraphs, Xubing Hao, Rashmie Abeysinghe, Jay Shi, Guo-Qiang Zhang, Licong Cui

Faculty, Staff and Student Publications

Ensuring the completeness of IS-A relations in SNOMED CT is crucial for maintaining its accuracy in clinical applications. In this study, we propose a hybrid approach leveraging non-lattice subgraphs and pre-trained language models (PLMs) to identify missing IS-A relations in SNOMED CT. We fine-tuned four BERT-based models: BERT, DistillBERT, DeBERTa, and BioClinicalBERT, and four generative large language models (LLMs): BioMistral, Llama3, Gemma2, and Phi-4. Missing IS-A relations were identified through consensus predictions by all eight models. De-BERTa achieved the best performance (precision: 0.96, recall: 0.97, F1-score: 0.965) for IS-A relation prediction. Our approach identified 678 potential missing IS-A relations in …


Relational Database-Based Resource-Provenance Visualization Engine: With An Application To Bican Data, Xiaojin Li, Yan Huang, Lydia Ng, Kimberly A Smith, Wei-Chun Chou, Rashmie Abeysinghe, Ling Tong, Shiwe Lin, Licong Cui, Shiqiang Tao, Guo-Qiang Zhang Jan 2024

Relational Database-Based Resource-Provenance Visualization Engine: With An Application To Bican Data, Xiaojin Li, Yan Huang, Lydia Ng, Kimberly A Smith, Wei-Chun Chou, Rashmie Abeysinghe, Ling Tong, Shiwe Lin, Licong Cui, Shiqiang Tao, Guo-Qiang Zhang

Faculty, Staff and Student Publications

Provenance tracking ensures data integrity, security, and accountability in healthcare and biomedical research. As biomedical data grows in complexity, comprehensive tracking mechanisms are needed to maintain reproducibility, transparency, and compliance with regulatory standards, such as GDPR. Traditional log-based and ontology-based approaches capture and standardize data lineage, while cryptographic and blockchain-based methods enhance security and verifiability. However, challenges remain in scalability, security, and usability. To address these, we introduce the Resource-Provenance Visualization Engine (RPVE), an advanced system integrating data lineage tracking and interactive visualization. RPVE employs the Randomized N-gram Hashing Identifier (NHash ID) to establish precise data links within the BRAIN …


Epidemiology Of Invasive Candidiasis, Derek J Bays, Emily N Jenkins, Meghan Lyman, Tom Chiller, Nora Strong, Luis Ostrosky-Zeichner, Martin Hoenigl, Peter G Pappas, George R Thompson Iii Jan 2024

Epidemiology Of Invasive Candidiasis, Derek J Bays, Emily N Jenkins, Meghan Lyman, Tom Chiller, Nora Strong, Luis Ostrosky-Zeichner, Martin Hoenigl, Peter G Pappas, George R Thompson Iii

Faculty, Staff and Student Publications

Invasive candidiasis (IC) is an increasingly prevalent, costly, and potentially fatal infection brought on by the opportunistic yeast, Candida. Previously, IC has predominantly been caused by C. albicans which is often drug susceptible. There has been a global trend towards decreasing rates of infection secondary to C. albicans and a rise in non-albicans species with a corresponding increase in drug resistance creating treatment challenges. With advances in management of malignancies, there has also been an increase in the population at risk from IC along with a corresponding increase in incidence of breakthrough IC infections. Additionally, the emergence of …


Diagnostic Value Of Soluble Interleukin-2 Receptor In Patients Suffering Neurosarcoidosis: A Systematic Review, Aditya Chanpura, Rajesh K Gupta, Shitiz K Sriwastava, Jan Rahmig Jan 2024

Diagnostic Value Of Soluble Interleukin-2 Receptor In Patients Suffering Neurosarcoidosis: A Systematic Review, Aditya Chanpura, Rajesh K Gupta, Shitiz K Sriwastava, Jan Rahmig

Faculty, Staff and Student Publications

Background: Neurosarcoidosis is an inflammatory granulomatous disease. Up to 25% of occult sarcoidosis affecting the nervous system are only detected by autopsy. In addition, in recent years the suspicion arose that the soluble Interleukin-2 Receptor (sIL-2R) might be useful in differentiating between neurosarcoidosis and neurosarcoidosis-like diseases such as neurotuberculosis, multiple sclerosis, or cerebral lymphoma.

Objectives: Therefore, we aimed to systematically review randomized controlled trials (RCT), observational studies, and case-control studies evaluating sIL-2R levels in neurosarcoidosis patients.

Design: For this systematic review, a comprehensive literature search of electronic databases including EMBASE, The Web Of Science, The Cochrane Library, MEDLINE, and Google …


Editorial: Telestroke And Stroke Care Networks Beyond The Comprehensive Stroke Center, Amanda Jagolino-Cole, Alicia Zha, Imama A Naqvi, Jennifer J Majersik Jan 2024

Editorial: Telestroke And Stroke Care Networks Beyond The Comprehensive Stroke Center, Amanda Jagolino-Cole, Alicia Zha, Imama A Naqvi, Jennifer J Majersik

Faculty, Staff and Student Publications

No abstract provided.


Optimizing Educational Environments In Stroke And Neurovascular Fields, Amanda L Jagolino-Cole, Devin L Brown, Nicole Chiota-Mccollum, Andrew M Southerland, David S Liebeskind Jan 2024

Optimizing Educational Environments In Stroke And Neurovascular Fields, Amanda L Jagolino-Cole, Devin L Brown, Nicole Chiota-Mccollum, Andrew M Southerland, David S Liebeskind

Faculty, Staff and Student Publications

No abstract provided.


Evolution Of Whole Blood Trauma Resuscitation In Childbearing Age Females: Practice Patterns And Trends, Alexandra Mp Brito, Mark H Yazer, Jason L Sperry, James F Luther, Stephen R Wisniewski, Frances Guyette, Ernest E Moore, Bryan A Cotton, Laura Vincent, Erin Fox, Jeremy W Cannon, Nicholas Namias, Joseph P Minei, Lee Anne Ammons, Skye Clayton, Martin Schreiber Jan 2024

Evolution Of Whole Blood Trauma Resuscitation In Childbearing Age Females: Practice Patterns And Trends, Alexandra Mp Brito, Mark H Yazer, Jason L Sperry, James F Luther, Stephen R Wisniewski, Frances Guyette, Ernest E Moore, Bryan A Cotton, Laura Vincent, Erin Fox, Jeremy W Cannon, Nicholas Namias, Joseph P Minei, Lee Anne Ammons, Skye Clayton, Martin Schreiber

Faculty, Staff and Student Publications

Background: The use of low titer group O whole blood (LTOWB) for resuscitation of patients with traumatic hemorrhage is becoming increasingly common. Practices regarding the administration of RhD-positive LTOWB to childbearing age females (CBAFs) vary between institutions due to concerns about RhD alloimmunization. This study examined practices related to LTOWB transfusion as they pertain to age and sex.

Methods: This was a secondary analysis of the Shock, Whole blood, and Assessment of TBI (traumatic brain injury) trial, a prospective, multicenter observational cohort study where outcomes following LTOWB transfusion were analyzed at seven level 1 trauma centers between 2018 and 2021, …


Perspective: The Evolution Of Hormones And Person Perception-A Quantitative Genetic Framework, Christopher I Gurguis, Tyler S Kimm, Teresa A Pigott Jan 2024

Perspective: The Evolution Of Hormones And Person Perception-A Quantitative Genetic Framework, Christopher I Gurguis, Tyler S Kimm, Teresa A Pigott

Faculty, Staff and Student Publications

Evolutionary biology provides a unifying theory for testing hypotheses about the relationship between hormones and person perception. Person perception usually receives attention from the perspective of sexual selection. However, because person perception is one trait in a suite regulated by hormones, univariate approaches are insufficient. In this Perspectives article, quantitative genetics is presented as an important but underutilized framework for testing evolutionary hypotheses within this literature. We note tacit assumptions within the current literature on psychiatric genetics, which imperil the interpretation of findings thus far. As regulators of a diverse manifold of traits, hormones mediate tradeoffs among an array of …


Intra-Decadal Increase In Globally-Spread Magallana Gigas In Southern California Estuaries, Marah L Wolfe, Chelsea M Bowers-Doerning, Anabell Espinosa, Ty Frantz, William J Hoese, Joann G Lam, Kailee R Lamp, Rachael A Lyons, Justin K Nguyen, Bryce D Keyes, Jada Smith, Holly L Suther, Meaghan Swintek, Juliann C Vannordstrand, Danielle C Zacherl Jan 2024

Intra-Decadal Increase In Globally-Spread Magallana Gigas In Southern California Estuaries, Marah L Wolfe, Chelsea M Bowers-Doerning, Anabell Espinosa, Ty Frantz, William J Hoese, Joann G Lam, Kailee R Lamp, Rachael A Lyons, Justin K Nguyen, Bryce D Keyes, Jada Smith, Holly L Suther, Meaghan Swintek, Juliann C Vannordstrand, Danielle C Zacherl

Faculty, Staff and Student Publications

Introduction and establishment of non-indigenous species (NIS) has been accelerated on a global scale by climate change. NIS Magallana gigas' (formerly Crassostrea gigas') global spread over the past several decades has been linked to warming waters, specifically during summer months, raising the specter of more spread due to predicted warming. We tracked changes in density and size distribution of M. gigas in two southern California, USA bays over the decade spanning 2010-2020 using randomly placed quadrats across multiple intertidal habitats (e.g., cobble, seawalls, riprap) and documented density increases by 2.2 to 32.8 times at 7 of the 8 sites surveyed …


Association Of Risk Factors And Comorbidities With Chronic Pain In The Elderly Population, Neil Mookerjee, Nicole Schmalbach, Gianna Antinori, Subhadra Thampi, Dylan Windle-Puente, Amy Gilligan, Ha Huy, Megha Andrews, Angela Sun, Roshni Gandhi, William Benedict, Austin Chang, Ben Sanders, Justin Nguyen, Maanika Reddy Keesara, Janet Aliev, Aneri Patel, Isaiah Hughes, Ian Millstein, Krystal Hunter, Satyajeet Roy Jan 2024

Association Of Risk Factors And Comorbidities With Chronic Pain In The Elderly Population, Neil Mookerjee, Nicole Schmalbach, Gianna Antinori, Subhadra Thampi, Dylan Windle-Puente, Amy Gilligan, Ha Huy, Megha Andrews, Angela Sun, Roshni Gandhi, William Benedict, Austin Chang, Ben Sanders, Justin Nguyen, Maanika Reddy Keesara, Janet Aliev, Aneri Patel, Isaiah Hughes, Ian Millstein, Krystal Hunter, Satyajeet Roy

Faculty, Staff and Student Publications

INTRODUCTION/OBJECTIVE: Chronic pain disorders affect about 20% of adults in the United States, and it disproportionately affects individuals living in the neighborhoods of extreme socioeconomic disadvantage. In many instances, chronic pain has been noted to arise from an aggregation of multiple risk factors and events. Therefore, it is of importance to recognize the modifiable risk factors. The aim of this study was to investigate the comorbid medical conditions and risk factors associated with chronic pain disorders in patients aged 65 years and older.

METHODS: Our team retrospectively reviewed medical records of elderly patients (65 years and older) who were evaluated …


Measurement Of 8-Hydroxy-2′-Deoxyguanosine In Serum And Cerebrospinal Fluid Of Horses With Neuroaxonal Degeneration And Other Causes Of Proprioceptive Ataxia, Megan Palmisano, Jeaneen Kulp, Susan Bender, Darko Stefanovski, Mary Robinson, Amy Johnson Jan 2024

Measurement Of 8-Hydroxy-2′-Deoxyguanosine In Serum And Cerebrospinal Fluid Of Horses With Neuroaxonal Degeneration And Other Causes Of Proprioceptive Ataxia, Megan Palmisano, Jeaneen Kulp, Susan Bender, Darko Stefanovski, Mary Robinson, Amy Johnson

Faculty, Staff and Student Publications

BACKGROUND: Eight-hydroxy-2'-deoxyguanosine (8-OHdG), a biomarker of oxidative damage evaluated in human neurodegenerative disease, has potential to correlate with postmortem diagnosis of neuroaxonal dystrophy/degenerative myeloencephalopathy (NAD/DM) in horses.

HYPOTHESIS: We hypothesized that 8-OHdG will be higher in CSF and serum from NAD/DM horses compared with horses with other neurologic diseases (CVSM, EPM) and a control group of neurologically normal horses. We also hypothesized that 8-OHdG will be higher in CSF compared with serum from NAD/DM horses.

ANIMALS: Fifty client-owned horses with postmortem diagnoses: 20 NAD/DM, 10 CVSM, 10 EPM, and 10 control horses. Serum and CSF samples were obtained between November …