Digital Commons Network^™

Uncovering Upconversion Photoluminescence In Layered Pbi2 Above Room Temperature, Sharad Ambardar, Xiaodong Yang, Jie Gao

Mechanical and Aerospace Engineering Faculty Research & Creative Works

As a van der Waals (vdW) layered semiconductor material, lead iodide (PbI2) possessing a direct bandgap with strong photoluminescence emission in visible range has gained wide attention in applications of photonic and optoelectronic devices. Here, up conversion photoluminescence (UPL) in exfoliated PbI2 flakes is demonstrated at room temperature and elevated temperatures. The linear power dependence of UPL emission with 532 nm excitation suggests the one-photon involved multiphonon-assisted UPL emission process, which is revealed by the temperature-dependent UPL emission measurement. Meanwhile, the nonlinear power dependence of UPL emission with 561 nm excitation indicates the transition of UPL emission mechanism from linear …

Fpga-Based Sensors For Distributed Digital Manufacturing Systems: A State-Of-The-Art Review, Laraib Khan, Sriram Praneeth Isanaka, Frank Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

The combination of distributed digital factories (D2Fs) with sustainable practices has been proposed as a revolutionary technique in modern manufacturing. This review paper explores the convergence of D2F with innovative sensor technology, concentrating on the role of Field Programmable Gate Arrays (FPGAs) in promoting this paradigm. A D2F is defined as an integrated framework where digital twins (DTs), sensors, laser additive manufacturing (laser-AM), and subtractive manufacturing (SM) work in synchronization. Here, DTs serve as a virtual replica of physical machines, allowing accurate monitoring and control of a given manufacturing process. These DTs are supplemented by sensors, providing near-real-time data to …

Incorporating An Analytical Approach To Ethical Reasoning Into An Ethics Case Conference For Residents, Holland Kaplan, Alyssa Kahl, Jonathan Lim

Center for Medical Ethics and Health Policy Staff Publications

Educating residents to apply ethical principles in clinical practice is critical in achieving standards in professionalism. We implemented biweekly ethics morning report case conferences incorporating a validated analytical tool in medical ethics, the Four-Box Method, from July 2022 to June 2023 in our internal medicine residency program. In 24 ethics morning reports, over 73% of participants reported that the intervention helped them achieve each of three learning objectives in ethics education. Ninety-two percent of cases addressed > 1 ethical issue. Our intervention may be easily integrated into the morning report conference structure as an educational tool in medical ethics across internal …

Random C-Peptide And Islet Antibodies At Onset Predict Β Cell Function Trajectory And Insulin Dependence In Pediatric Diabetes, Mustafa Tosur, Saima Deen, Xiaofan Huang, Serife Uysal, Marcela Astudillo, Richard A Oram, Maria J Redondo, Farook Jahoor, Ashok Balasubramanyam

Children’s Nutrition Research Center Staff Publications

Objective: Identification of prognostic biomarkers in pediatric diabetes is important for precision medicine. We assessed whether C-peptide and islet autoantibodies are useful to predict the natural history of children with new-onset diabetes.

Methods: We prospectively studied 72 children with new-onset diabetes (median follow-up: 8 months) by applying the Aβ classification system ("A+": islet autoantibody positive, "β+": random serum C-peptide ≥1.3 ng/mL at diagnosis). Beta-cell function was assessed longitudinally with 2 hours postprandial/stimulated urinary C-peptide-to-creatinine ratio (UCPCR) 3-12 weeks (V1) and 6 to 12 months after diagnosis (V2). We obtained a type 1 diabetes genetic risk score for each participant, and …

Impact Of Prenatal Genomics On Clinical Genetics Practice, Roni Zemet, Ignatia B Van Den Veyver

Duncan NRI Faculty and Staff Publications

Genetic testing for prenatal diagnosis in the pre-genomic era primarily focused on detecting common fetal aneuploidies, using methods that combine maternal factors and imaging findings. The genomic era, ushered in by the emergence of new technologies like chromosomal microarray analysis and next-generation sequencing, has transformed prenatal diagnosis. These new tools enable screening and testing for a broad spectrum of genetic conditions, from chromosomal to monogenic disorders, and significantly enhance diagnostic precision and efficacy. This chapter reviews the transition from traditional karyotyping to comprehensive sequencing-based genomic analyses. We discuss both the clinical utility and the challenges of integrating prenatal exome and …

Langerhans Cell Histiocytosis In Children Born After Assisted Reproductive Technology, Carrie L Williams, Kathryn J Bunch, Charles Stiller, Michael F G Murphy, Beverley J Botting, Melanie C Davies, Barbara Luke, Philip J Lupo, Alastair G Sutcliffe

Center for Medical Ethics and Health Policy Staff Publications

Research question: Are children born after assisted reproductive technology (ART) at higher risk of developing Langerhans cell histiocytosis (LCH)?

Design: Records of children born after ART recorded by the UK Human Fertilisation & Embryology Authority were linked to National Registry of Childhood Tumours records to determine the number of children developing LCH. Calculated person-years at risk were used in conjunction with the incidence of LCH in the general population to determine the expected number of cases if the cohort had the same incidence as the general population with similar age and sex, over the same calendar years. The standardized incidence …

Meeting Aerobic Physical Activity Guidelines And Associations With Physical Fitness In Men With Metastatic Prostate Cancer: Baseline Results Of The Multicentre Interval-Gap4 Trial, Lisa Umlauff, Stacey A. Kenfield, Robert U. Newton, Nicolas H. Hart, Fred Saad, Kerry S. Courneya, Rosemary Greenwood, Wilhelm Bloch, Moritz Schumann

Research outputs 2022 to 2026

Background: This study compared the physical activity level of men with metastatic prostate cancer at baseline of the multicentre INTERVAL-GAP4 trial to the American Cancer Society guidelines and examined associations with physical fitness. Methods: A total of 140 men on androgen deprivation therapy (ADT) were included in this cross-sectional analysis of baseline data from the INTERVAL-GAP4 trial. Exclusion criteria included a maximum of 1 h of vigorous aerobic exercise or one structured resistance exercise session per week but no restrictions on habitual physical activity. Moderate-to-vigorous physical activity (MVPA) was assessed using a modified Godin–Shephard Leisure-Time Physical Activity Questionnaire. Physical fitness …

Investment By Maternal Grandmother Buffers Children Against The Impacts Of Adverse Early Life Experiences, Samuli Helle, Antti O. Tanskanen, David A. Coall, Gretchen Perry, Martin Daly, Mirkka Danielsbacka

Research outputs 2022 to 2026

Exogenous shocks during sensitive periods of development can have long-lasting effects on adult phenotypes including behavior, survival and reproduction. Cooperative breeding, such as grandparental care in humans and some other mammal species, is believed to have evolved partly in order to cope with challenging environments. Nevertheless, studies addressing whether grandparental investment can buffer the development of grandchildren from multiple adversities early in life are few and have provided mixed results, perhaps owing to difficulties drawing causal inferences from non-experimental data. Using population-based data of English and Welsh adolescents (sample size ranging from 817 to 1197), we examined whether grandparental investment …

Patient Experiences: A Qualitative Systematic Review Of Chemotherapy Adherence, Amineh Rashidi, Susma Thapa, Wasana Sandamali Kahawaththa Palliya Guruge, Shubhpreet Kaur

Research outputs 2022 to 2026

Adherence to chemotherapy treatment is recognized as a crucial health concern, especially in managing cancer patients. Chemotherapy presents challenges for patients, as it can lead to potential side effects that may adversely affect their mobility and overall function. Patients may sometimes neglect to communicate these side effects to health professionals, which can impact treatment management and leave their unresolved needs unaddressed. However, there is limited understanding of how patients’ experiences contribute to improving adherence to chemotherapy treatment and the provision of appropriate support. Therefore, gaining insights into patients’ experiences is crucial for enhancing the accompaniment and support provided during chemotherapy. …

The Impact Of Armed Conflicts On Hiv Treatment Outcomes In Sub-Saharan Africa: A Systematic Review And Meta-Analysis, Hafte Kahsay Kebede, Hailay Abrha Gesesew, Amanuel Tesfay Gebremedhin, Paul Ward

Research outputs 2022 to 2026

Background: Despite the fact that Sub-Saharan Africa bears a disproportionate burden of armed conflicts and HIV infection, there has been inadequate synthesis of the impact of armed conflict on HIV treatment outcomes. We summarized the available evidence on the impact of armed conflicts on HIV treatment outcomes in Sub-Saharan Africa from 2002 to 2022. Methods: We searched four databases; MEDLINE, PubMed, CINHAL, and Scopus. We also explored grey literature sources and reviewed the bibliographies of all articles to identify any additional relevant studies. We included quantitative studies published in English from January 1, 2002 to December 30, 2022 that reported …

Pain Prevalence, Intensity, And Association With Neuropsychiatric Symptoms Of Dementia In Immigrant And Non-Immigrant Aged Care Residents In Australia, Pelden Chejor, Mustafa Atee, Patricia Cain, Daniel Whiting, Thomas Morris, Davina Porock

Research outputs 2022 to 2026

Pain recognition for culturally diverse people is complex as pain experience is subjective and influenced by cultural background. We compared the prevalence, intensity, and association of pain with neuropsychiatric symptoms (NPS) between immigrants and non-immigrants living with dementia in residential aged care homes (RACHs) who were referred to two Dementia Support Australia programs. Immigrant status was defined by the documented country of birth. Pain and NPS were assessed using PainChek® and the Neuropsychiatric Inventory, respectively. Subgroup analyses were also completed for English-speaking and non-English-speaking immigrants. A total of 17,637 referrals [immigrants, n = 6340; non-immigrants, n = 11,297] from 2792 …

Life In Sitcoms: Episodes In Love And Loss, Amy Kielmeyer

Theses and Dissertations

Sitcoms have been an enduring part of television history, but for as much as they have been an important part of the ways we’ve interacted with television, they have also been criticized over the years for being too the same, too unrealistic, for avoiding complexity, and minimizing the lived experiences of many people. These critiques are necessary, but they can also overlook some of the ways that these very critiques are part of what makes the sitcom a valuable vehicle for telling familiar stories. Using sitcoms, obituaries, and poetry, this collection of creative nonfiction offers ways of looking at sitcoms …

Development, Characterization, And Application Of Nanomaterials For Target Detection And Therapeutic Study, Yingfen Wu

Theses and Dissertations

Nanomaterials have emerged as a pivotal area of research in chemistry, driven by their unique properties that make them suitable for both industrial and biomedical applications. Among nanomaterials, nanozyme is a series of nanomaterials with enzyme-mimetic activities that can proceed with the catalytic reactions of natural enzymes, conferring significant potential for their use in various biomedical applications. Herein, we describe three types of nanomaterials products with distinct properties and applications: 1) Fe³⁺-doped graphene quantum dots (GQDs) for sensitive H₂O₂ detection; 2) ratiometric fluorescent nanoprobes based on near-infrared (NIR) semiconducting polymer dots for label-free detection of dopamine; and 3) Multifunctional near …

Developing Inclusive Practices Through Peer Coaching In College Science Teaching, Briana Miller

Theses and Dissertations

Historically underrepresented students pursuing STEM majors encounter systemic barriers. Students are more likely to experience success when faculty implement inclusive practices. Faculty often lack the pedagogical training necessary to adopt inclusive practices, further perpetuating inequities. To eliminate barriers and offer equitable opportunities for success in STEM majors, this case study explores the implementation of peer coaching and Culturally Relevant Science Teaching (CRST) in college level science teaching, focusing on the experiences of three participating faculty. Through a year-long professional development (PD) cycle, three science faculty members from a small liberal arts college engaged in reflective practices aimed at improving their …

Development Of Fluorescent-Based Nanoparticles For Bioimaging, Gene Regulation Expression, And Photo-Induced Synergistic Cancer Therapy, Di Sun

Theses and Dissertations

Fluorescent-based nanoparticles have been applied to a broad range of biological applications, as discussed in this dissertation, including bioimaging, gene regulation expression, and photo-induced synergistic cancer therapy. Prior to applications, this dissertation first focused on the development and characterization of several fluorescent-based nanoparticles using different methods. These include 1) Streamlined synthesis of dual-emissive fluorescent-based silicon quantum dots (SiQDs). The SiQDs were generated as a promising, non-toxic labeling tool for bioimaging of a variety of cell types. both in visible and near-infrared (NIR) ranges. 2) Polymer-based nanoparticles - Polymer dots (Pdots) with a strong NIR fluorescence. The Pdots were functionalized as …

Personality Across Realities: Correlations Between Personality Profiles And Preferences Within Roleplaying Games, Brittany Lee Mancha

Theses and Dissertations

Clinically maladaptive behaviors and personality types have been studied within gamers, both those who play video games and those who roleplay in tabletop games. However, the connection between personality types and the preferences of the players themselves in what and how they roleplay is just barely being studied. Personality traits, such as extraversion/introversion and motivation by pain or pleasure, may be both influencing the gameplay decisions and preferences of players, and vice versa. A total of 500 respondents completed the Millon Index of Personality Styles, Revised (MIPS-R), followed by a demographics survey and finally a survey assessing Dungeons and Dragons', …

Investigating The Relationship Between Teachers’ State Evaluation Rating And Their Classroom-Based Assessment Practices And Systems, Christopher Jones

Theses and Dissertations

This quantitative research study investigates the relationship between teachers’ evaluation rating and their classroom-based assessment practices using a survey approach. Four middle schools consisting of 39 (grades six through eight) teachers in the Southwestern U.S. participated in the study. Research has shown that when teachers regularly use a system of evidence-based classroom assessment practices, student achievement increases. The problem addressed within this investigation is that students nationwide are performing at lower proficiency rates in math and English Language Arts than previously seen. Results from this study indicate that even teachers rated “highly effective” on evaluations are not employing evidence-based assessment …

Elementary Teacher Instructional Self-Efficacy In Leader In Me Lighthouse Schools, Lara Storm

Theses and Dissertations

This study is a secondary data comparative analysis using the Leader in Me Measurable Results Assessment (MRA) to examine whether teachers at Leader in Me Lighthouse certified schools have a greater degree of instructional self-efficacy than teachers at non-Lighthouse certified Leader in Me schools. Literature shows that students in classes with teachers that have a higher degree of instructional self-efficacy experience higher student achievement and a more supportive classroom climate. In addition, those teachers with higher efficacy experience lower levels of stress and burnout and are more engaged in professional development. The guiding notion of this investigation is that implementing …

“How Can I Teach When I Was Not Taught How?”: Teacher Education For Mother Tongue Instruction For Stem In Southwest Nigeria, Motunrayo Adeosun

Theses and Dissertations

In this qualitative study, the experiences, training, and challenges of teachers in primary schools in a community in southwest Nigeria were explored. The purpose of this study was to identify the experiences of teachers about their training for mother tongue instruction and how they teach pupils with the mother tongue or local language of the community, the challenges faced by teachers in teaching with the mother tongue, and the strategies used by teachers to overcome the challenges. This study found that teachers received no training and there is no curriculum for the training of teachers to teach in the mother …

Targeting World Language Learning In The Target Language: A Qualitative Inquiry Of The K–12 Foreign Language Teacher Experience, Igor Ljevaja

Theses and Dissertations

This qualitative study explores the current practices of K–12 foreign language teachers (FLTs) in using the target language (TL) within an urban school district in the Midwest United States. Focusing on how FLTs engage in professional development (PD) to optimize their TL use in the classroom, the study investigates the strategies and knowledge FLTs employ to foster TL proficiency among students. Purposeful sampling was employed to recruit participants (n = 5) who represented full-time FLTs, taught between sixth and 12th grade, and had at least four years of teaching experience and valid state licenses. Semi-structured interviews with current FLTs provide …

Using Problematic Sexual Behaviors And The Developmental Life Course Model To Predict Criminal Justice Involvement And Psychopathology By Early Adulthood, Amanda Schwartz

Theses and Dissertations

The developmental life course (DLC) model explains risk factors and developmental patterns among juveniles who have committed more than one sexual offense by considering the impact of major life events, experiences, and risk and protective factors throughout various developmental stages. Using an archival longitudinal dataset, the Longitudinal Studies of Child Abuse and Neglect (LONGSCAN), this study applied the DLC model to explore the relationship between gender and onset and persistence of problematic sexual behaviors (PSBs) in childhood and adolescence with criminal justice involvement and psychopathology by early adulthood (N = 330, 46% male, M = 18.26 years) after controlling for …

The Fcc 5-Year Deorbit Rule’S Impact On The Space Industry Including Non-Traditional Scientific And Environmental Stakeholders, Kristin Shahady

Theses and Dissertations

In pursuit of a safer and more sustainable space environment, the Federal Communications Commission (FCC) introduced the 5-year deorbit rule, a regulatory mandate aimed at mitigating space debris by requiring satellite operators to remove their spacecraft from LEO within 5 years after their mission is complete. While the intent behind this rule is admirable in the desire to remediate and limit the generation of orbital debris, it raises questions whether it was crafted with consideration of all stakeholders, whether it will truly mitigate the creation of orbital debris, and whether it exhibits characteristics of arbitrariness and capriciousness. Agencies’ actions be …

Applied Indigenous Knowledge Translation: Naatookyookaasii, Lynn Marie Mad Plume

Theses and Dissertations

This dissertation portfolio comprises three projects aimed at advancing Indigenous health and integrating cultural perspectives into research and practice. Guided by principles of community engagement and ethical research practices, these projects align closely with my career goals in Indigenous health policy and research. The first project, "Measuring Wellness Through Indigenous Partnerships," is a scoping review that examines global Indigenous wellness measures and assesses community involvement in defining measures of wellness. This review informs future practice directions and supports my advocacy for culturally responsive methodology. The second project, "Reciprocal Facilitation: Protocols and Practices for Listening Sessions with Tribal Communities," introduces a …

Bst2 Facilitates Activation Of Hematopoietic Stem Cells Through Erk Signaling, Marcus A Florez, Apoorva Thatavarty, Duy T Le, Holly A Hill, Youngjae Jeong, Brian M Ho, Pawel Kus, Trisha K Wathan, Bailee N Kain, Shixia Huang, Dongsu Park, Katherine Y King

Faculty, Staff and Students Publications

The proinflammatory cytokine interferon-gamma (IFNγ) is upregulated in a variety of infections and contributes to bone marrow failure through hematopoietic stem cell (HSC) activation and subsequent exhaustion. The cell surface protein, bone marrow stromal antigen 2 (BST2), is a key mediator of this process, as it is induced upon interferon stimulation and required for interferon-dependent HSC activation. To identify the mechanism by which BST2 promotes interferon-dependent HSC activation, we evaluated its role in niche localization, immune cell function, lipid raft formation, and intracellular signaling. Our studies indicated that knock out (KO) of BST2 in a murine model does not disrupt …

Osteogenesis Imperfecta: Skeletal And Non-Skeletal Challenges In Adulthood, Jannie Dahl Hald, Bente Langdahl, Lars Folkestad, Lena Lande Wekre, Riley Johnson, Sandesh C S Nagamani, Cathleen Raggio, Stuart H Ralston, Oliver Semler, Laura Tosi, Eric Orwoll

Faculty, Staff and Students Publications

Osteogenesis imperfecta (OI) is a Mendelian connective tissue disorder associated with increased bone fragility and other clinical manifestations most commonly due to abnormalities in production, structure, or post-translational modification of type I collagen. Until recently, most research in OI has focused on the pediatric population and much less attention has been directed at the effects of OI in the adult population. This is a narrative review of the literature focusing on the skeletal as well as non-skeletal manifestations in adults with OI that may affect the aging individual. We found evidence to suggest that OI is a systemic disease which …

Persistent Growth-Promoting Effects Of Vosoritide In Children With Achondroplasia Are Accompanied By Improvements In Physical And Social Aspects Of Health-Related Quality Of Life, Ravi Savarirayan, Melita Irving, William R Wilcox, Carlos A Bacino, Julie E Hoover-Fong, Paul Harmatz, Lynda E Polgreen, Klaus Mohnike, Carlos E Prada, Takuo Kubota, Paul Arundel, Antonio Leiva-Gea, Richard Rowell, Andrea Low, Ian Sabir, Alice Huntsman-Labed, Jonathan Day

Faculty, Staff and Students Publications

Purpose: Evaluate the impact of vosoritide on health-related quality of life in children with achondroplasia.

Methods: Participants received vosoritide (15 μg/kg/day) in an extension trial (NCT03424018) after having participated in a placebo-controlled trial (NCT03197766).

Results: The population comprised 119 participants (mean [SD] age 9.7 [2.6] years). Mean treatment duration was 4 (0.78) years. At year 3, the largest mean (SD) changes were observed in the Quality of Life of Short Stature Youth physical score (5.99 [19.41], caregiver reported; 6.32 [20.15], self-reported) and social score (2.85 [8.29] and 6.76 [22.64], respectively). Changes were greatest in participants with …

Death And Words As Witness In Post-War Literature: Salvation Narratives In Markus Zusak’S The Book Thief, Lusa Holmstrom

FCRH Honors Program Theses

Death didn’t used to be so taboo. As late as the 18th century, death was a prominent aspect of literature, and people of all ages were invited to the deathbeds of family members and friends alike. In the Victorian era, death was so much a culture as was living. But with the rise of preventative medicine in the late 19th and early 20th centuries, the view of death in the western world, specifically, took a turn. As Geoffrey Gorer argues in his 1955 article “The Pornography of Death,” higher mortality rates allowed for greater familiarity and intimacy with death, while …

Maternal Glycemic Status And Longitudinal Fetal Body Composition And Organ Volumes Based On Three-Dimensional Ultrasonography, Kathryn A Wagner, Jessica L Gleason, Zhen Chen, Cuilin Zhang, Stefanie N Hinkle, Dian He, Wesley Lee, Roger B Newman, John Owen, Daniel W Skupski, William A Grobman, Seth Sherman, Fasil Tekola-Ayele, Jagteshwar Grewal, Katherine L Grantz

Faculty, Staff and Students Publications

Objective: Gestational diabetes mellitus (GDM) increases the risk of fetal overgrowth as measured by two-dimensional ultrasonography. Whether fetal three-dimensional (3D) soft tissue and organ volumes provide additional insight into fetal overgrowth is unknown.

Research design and methods: We prospectively evaluated longitudinal 3D fetal body composition and organ volumes in a diverse U.S. singleton pregnancy cohort (2015-2019). Women were diagnosed with GDM, impaired glucose tolerance (IGT), or normal glucose tolerance (NGT). Up to five 3D ultrasound scans measured fetal body composition and organ volumes; trajectories were modeled using linear mixed models. Overall and weekly mean differences in fetal 3D trajectories were …

International Classification System For Ocular Complications Of Anti-Vegf Agents In Clinical Trials, Marko M Popovic, Michael Balas, Srinivas R Sadda, David Sarraf, Ryan Huang, Sophie J Bakri, Audina Berrocal, Andrew Chang, Chui Ming Gemmy Cheung, Sunir Garg, Roxane J Hillier, Frank G Holz, Mark W Johnson, Peter K Kaiser, Peter J Kertes, Timothy Y Y Lai, Jason Noble, Susanna S Park, Yannis M Paulus, Giuseppe Querques, Aleksandra Rachitskaya, Paisan Ruamviboonsuk, Shohista Saidkasimova, Maria Teresa Sandinha, David H Steel, Hiroko Terasaki, Christina Y Weng, Basil K Williams, Lihteh Wu, Rajeev H Muni

Faculty, Staff and Students Publications

Purpose: Complications associated with intravitreal anti-VEGF therapies are reported inconsistently in the literature, thus limiting an accurate evaluation and comparison of safety between studies. This study aimed to develop a standardized classification system for anti-VEGF ocular complications using the Delphi consensus process.

Design: Systematic review and Delphi consensus process.

Participants: Twenty-five international retinal specialists participated in the Delphi consensus survey.

Methods: A systematic literature search was conducted to identify complications of intravitreal anti-VEGF agent administration based on randomized controlled trials (RCTs) of anti-VEGF therapy. A comprehensive list of complications was derived from these studies, and this list was subjected to …

Diabetter Together: Clinical Trial Protocol For A Strengths-Based Peer Mentor Intervention For Young Adults With Type 1 Diabetes Transitioning To Adult Care, Samantha A Carreon, Charles G Minard, Sarah K Lyons, Wendy Levy, Stephanie Camey, Kishan Desai, Brenda Duran, Randi Streisand, Barbara J Anderson, Siripoom V Mckay, Tricia S Tang, Sridevi Devaraj, Ryan Ramphul, Marisa E Hilliard

Faculty, Staff and Students Publications

Background: Type 1 diabetes (T1D) management is challenging for young adults, who are expected to transfer from the pediatric to adult T1D healthcare system while also managing typical developmental demands (e.g., social, financial, work/school, residential). Many young adults have extended gaps in care before following up in adult care, increasing risk for poor health outcomes. There are few evidence-based programs to support young adults with T1D to promote a timelier transition during this period. This paper reports on the design of DiaBetter Together, a randomized controlled trial to evaluate a 12-month Peer Mentor-delivered intervention compared to usual care among young …