Digital Commons Network^™

The Carbon Crater: Comparing Anthropogenic Greenhouse Gas Emissions To Historical Planetary Events, Hal T. Nelson, Paul Reynolds, Brian W. Jewett

Public Administration Faculty Publications and Presentations

Equilibrium climate sensitivity modeling relies heavily on paleoclimate records that were affected by meteorite impacts and volcanic explosions. This paper conducts a thought experiment by re-assembling known data and theories to shed new light on anthropogenic carbon waste. Anthropogenic activity, meteorite impacts and volcanic explosions all extract material from the Earth’s crust and deposit it in the atmosphere. This thought experiment tests if the mass of anthropogenic greenhouse gas emissions from 1851 to 2021 is comparable to the mass of atmospheric emissions from historical planetary events. Approximately 3.60 trillion tons of anthropogenic carbon dioxide equivalents are converted into volume and …

Mates: A Deep Learning-Based Model For Locus-Specific Quantification Of Transposable Elements In Single Cell, Ruohan Wang, Yumin Zheng, Zijian Zhang, Kailu Song, Erxi Wu, Xiaopeng Zhu, Tao P Wu, Jun Ding

Faculty, Staff and Students Publications

Transposable elements (TEs) are crucial for genetic diversity and gene regulation. Current single-cell quantification methods often align multi-mapping reads to either 'best-mapped' or 'random-mapped' locations and categorize them at the subfamily levels, overlooking the biological necessity for accurate, locus-specific TE quantification. Moreover, these existing methods are primarily designed for and focused on transcriptomics data, which restricts their adaptability to single-cell data of other modalities. To address these challenges, here we introduce MATES, a deep-learning approach that accurately allocates multi-mapping reads to specific loci of TEs, utilizing context from adjacent read alignments flanking the TE locus. When applied to diverse single-cell …

Irrigation Companies And The Great Salt Lake: Managing Water In Utah Amidst Climate Change, Chloe Francis, Kendall Becker, Matt Yost, Scott Hotaling

All Current Publications

The Great Salt Lake, a key ecosystem and major component of Utah’s identity and economy, is threatened by rapidly declining water levels. This problem has caused widespread and ongoing concern from the public, and the Utah Legislature is faced with making water allocation and management decisions to adapt to the state’s growing population and changing environment. One important group in this discussion is irrigation companies. Here, we examine how irrigation companies receive and maintain water rights in Utah, their significant role in water management, and recent legislative efforts to incentivize efficient water use so more water reaches the Great Salt …

A Feasibility Study Of A Music Enrichment Program On Relative Reinforcing Value Of Food And Home Environmental Enrichment Among Families Of Low Socioeconomic Status., Kai Ling Kong, Amy R. Smith, Brenda Salley, Deanna Hanson-Abromeit, Hideko Engel, Catherine Serwatka

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Emerging evidence suggests that low socioeconomic status (SES) home environments may play a role by promoting excess energy intake through a lack of access to non-food reinforcers. Because of the deleterious effects of SES-related disparities on child health and development, feasible and culturally acceptable interventions are urgently needed. Community-based music enrichment programs may be an ideal intervention strategy.

METHODS: In collaboration with a local non-profit organization and music studio, we conducted a pilot randomized controlled trial to assess the effects of a music enrichment program versus a play date control in a group of 9-24-month-old healthy infants (N = …

Costa Rican Culture Of Love, Melissa Johnson

First-Gen Voices: Creative and Critical Narratives on the First-Generation College Experience

This collection of photographs explores how the collectivist and vibrant culture of Costa Rica manifests as a profound sense of love, shared among humans, animals, and the land. This project celebrates the spirit of Costa Rica as a whole, where human connection, respect for the environment, and a genuine sense of community intertwine.

Shell Translucency: A Novel Eggshell Quality Parameter In Broiler Breeders, Duarte Neves, Austin Jasek, Colwayne Morris, Raquel Burin, Kevin Stephens, Marco Rebollo

Proceedings of the Arkansas Nutrition Conference

In the United States, nearly 240 million commercial broiler breeder eggs are incubated weekly with an average hatchability of 79.1% (Third Party Reporting). Between 160 eggs/hen and 125 chicks/hen the loss is considerable. In 2007, an estimated 1% improvement in hatchability would escalate profits by over $25 million to hatcheries and markedly increase profitability in broiler operations (Schaal and Gherian, 2007). In order to tap into top hatchability performances, egg management in commercial hatcheries such as egg storage time and conditions, incubation temperature and humidity, as well as turning frequency are of utmost importance (Vick et al., 1993; Reis et …

Interview: Interviewed By Steven Schnell Editor, The Geographical Bulletin, Thomas J. Baerwald

The Geographical Bulletin

Tom Baerwald is currently President of the Association of American Geographers, and is employed at the National Science Foundation, where he has served in many capacities, most recently as Senior Science Advisor in the Division of Behavioral and Cognitive Sciences and as a program director for the Geography and Regional Science Program. He also is a coordinator for environmental social and behavioral science activities, assisting in the conduct of multidisciplinary efforts that engage social and behavioral scientists in the studies of interactions among human and natural systems. He earned a B.A. in geography and history from Valparaiso University and both …

Nowhere, Usa, J. R. Sloan

Calliope

No abstract provided.

The Whimsical Testimony Of A Six-Year-Old Vampire, Talia Jordan

Calliope

No abstract provided.

Skull, John Mccoy

Calliope

No abstract provided.

As The Sea Caves In, Emma Bates

Calliope

No abstract provided.

Extending A Hand To A Wounded Gazelle, Destinney Ringer

Calliope

No abstract provided.

Full Issue

Calliope

No abstract provided.

Art And Climate : A Creative Awareness, Michel Abou Khalil

BAU Journal - Society, Culture and Human Behavior

The growing engagement of artists with ecological challenges is a significant trend in the Anthropocene era. Most often, some of them feel driven by a sense of responsibility regarding the impact of industry and consumer society on the environment. Their commitment becomes a form of activism, mobilization or even a simple commercial niche to exploit. By observing this enthusiasm in the art world for environmental issues, we can ask ourselves the following questions: despite their sometimes lack of in-depth knowledge, where does the role of artists begin and end in this complex universe? Does their commitment have real power to …

Nature Fears Emptiness : An Analytical Reading Of Emotional Emptiness, Mariange Merhi

BAU Journal - Society, Culture and Human Behavior

Nature does things well, but sometimes it takes crooked paths... In psychoanalysis, the role of the psychoanalyst, as of any other therapist, is not only to set clinical goals, to understand the psychic work of the patient and to accompany him in his self-discovery. Above all, it is supposed to manage the internal conflicts of the suffering subject. To do this, he seeks to shed light on his unconscious journey and detect the vagaries of his psychic functioning. He try to act on his commitment, motivation and adherence to the values of the society in which he lives, without hindering …

Of Ecological Identity In Literature Humus By Gaspard Koenig, Christelle Stephan Hayek

BAU Journal - Society, Culture and Human Behavior

« In 1978, William Rueckert, retired professor of English and American literature at the State University of New York at Geneseo, published an article entitled "Literature and Ecology. An Experiment in Ecocriticism" where the word ecocriticism was used for the first time. » (Posthumus, 2017, p. 161) This is how appeared a discipline which, over the decades, has gained in insight and relevance, and whose true theoretical foundations were finally laid by Professor Lawrence Buell, in his work The Environmental Imagination, published in 1995. At a time when one of the most crucial issues is climate change mainly due to …

Between The Imagination Of Legends And The Challenge Of Reality: Writing To Save The Planet, Nadia Iskandarani

BAU Journal - Society, Culture and Human Behavior

Climate change is a global phenomenon due to global warming, characterized by a general increase in average temperatures. This change is linked to industrial activity, in particular to the greenhouse effect, which is why it is said to be of human origin. Alongside scientists, writers now include themes linked to global warming. New genres have appeared such as climate fiction. Thomas B. Reverdy, in his novel Climax describes the end of the world in the context of global warming. The action takes place in the north, towards the Arctic. The story involves various protagonists who remember Norse legends about the …

Enhancing Human Aging Proteins Detection Based On Bio-Structural Deep Clustering Network, Sondos M. Hammad, Mohamed Talaat Saidahmed, Elsayed A. Sallam, Reda Elbasiony

Journal of Engineering Research

Aging is a major risk factor for numerous chronic diseases and declines in physical and cognitive functions, making it a critical focus of research. Identifying biomarkers that signify biological aging is crucial for developing interventions that can potentially delay age-related diseases. Among these biomarkers, human aging proteins are of significant interest. However, laboratory experiments to discover aging proteins are complex, costly, and time-consuming. Often focusing on single proteins at a time. To address this challenge, we used a clustering algorithm to detect potential human aging proteins. This approach aims to aid biologists in their experimental efforts. Deep clustering, particularly simultaneous …

The Thermoplastic Honeycomb As An Eco-Friendly Material For Shelters, Neveen Youssef Azmy, Wesam Aeh Mehanna, Aya Fouad Kahla

Journal of Engineering Research

Nature-inspired design offers distinct environmental characteristics and makes them valuable in the development of structural designs within the construction industry, owing to their inherent natural and aesthetic qualities. Hexagonal structures exhibit remarkable mechanical, structural, and environmental attributes. Consequently, this research focuses on investigating honeycomb configurations composed of thermoplastic materials that engage thermally with the surrounding environment, as well as exploring their applications in temporary structures. The research aims to contribute to a temporary design model for shelter to protect the environment well and improve energy consumption by using a thermoplastic honeycomb to sustainable environment. A specialized model was developed to …

First Demonstration Of In Vivo Pde11a4 Target Engagement For Potential Treatment Of Age-Related Memory Disorders, Shams Ul Mahmood, Jeremy Eberhard, Charles S. Hoffman, Dennis Colussi, John Gordon, Wayne Childers, Elvis Amurrio, Janvi Patel, Michy P. Kelly, David P. Rotella

Department of Chemistry and Biochemistry Faculty Scholarship and Creative Works

PDE11A4 is a target of interest for the treatment of age-related memory disorders. A previous report from our laboratories described an amide series of potent, selective PDE11A4 inhibitors that was metabolically unstable. Investigation of heterocyclic amide isosteres for the labile amide moiety revealed distinct structure-activity relationships and identified several compounds with potency comparable to the amide series. This manuscript describes the characterization of structure-activity and structure-property relationships in this set, leading to the identification of an orally bioavailable, brain-penetrant, selective and potent PDE11A4 inhibitor. Target engagement experiments demonstrated PDE11A4 inhibition in the hypothalamus of mice that was absent in PDE11A4 …

Standards And Best Practices For Assigning Subject Headings To Moving Images, Scott Dutkiewicz, Tomeka Jackson, Jen M. Jones

Presentations

This presentation discusses principles from assigning subject headings to moving images using case studies. Our focus is on the Library of Congress Subject Headings (LCSH).

The Heart-Brain Axis: Exploring Shared Genetic Signatures And Environmental Modifiers On Heart Failure And Alzheimer’S Disease Pathology, Helen Butler

MUSC Theses and Dissertations

Heart failure (HF) and Alzheimer’s Disease (AD) are two leading causes of death in the United States. Conventionally viewed as independent conditions, HF/AD coexist in ~30% of patients and are mechanistically linked by shared genetic and biochemical characteristics. The del Monte lab has established the concept of the heart-brain axis through human samples and murine models, providing a framework for this dissertation which focuses on the interplay between genetics and the environment in shaping the heterogeneity of disease phenotypes.

1) Loss of function mutations in presenilin (PSEN1/2) genes represent overlapping genetic signatures in AD/HF. Presenilins form the g-secretase …

A Simple And Fast Optical Clearing Method For Whole-Mount Fluorescence In Situ Hybridization (Fish) Imaging, Junwoo Suh, Yehe Liu, Jordan Smith, Michiko Watanabe, Andrew M. Rollins, Michael W. Jenkins

Faculty Scholarship

We report a single-step optical clearing method that is compatible with RNA fluorescence in situ hybridization (FISH) imaging. We previously demonstrated microscopy imaging with immunohistochemistry and genetic reporters using a technique called lipid-preserving refractive index matching for prolonged imaging depth (LIMPID). Our protocol reliably produces high-resolution three-dimensional (3D) images with minimal aberrations using high magnification objectives, captures large field-of-view images of whole-mount tissues, and supports co-labeling with antibody and FISH probes. We also custom-designed FISH probes for quail embryos, demonstrating the ease of fabricating probes for use with less common animal models. Furthermore, we show high-quality 3D images using a …

Molecular Characterization Of Sterol C4-Methyl Oxidase In Leishmania Major, Yu Ning, Somrita Basu, Fong-Fu Hsu, Mei Feng, Michael Zhuo Wang, Kai Zhang

2020-Current year OA Pubs

Sterol biosynthesis requires the oxidative removal of two methyl groups from the C-4 position by sterol C-4-demethylase and one methyl group from the C-14 position by sterol C-14-demethylase. In

Montana Kaimin, October 10, 2024, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Quaker Campus, October 10, 2024 (Vol. 23, Issue 4), Whittier College

Quaker Campus

No abstract provided.

Systematic Perturbations Of Setd2, Nsd1, Nsd2, Nsd3, And Ash1l Reveal Their Distinct Contributions To H3k36 Methylation, Gerry A Shipman, Reinnier Padilla, Cynthia Horth, Bo Hu, Eric Bareke, Francisca N Vitorino, Joanna M Gongora, Benjamin A Garcia, Chao Lu, Jacek Majewski

2020-Current year OA Pubs

BACKGROUND: Methylation of histone 3 lysine 36 (H3K36me) has emerged as an essential epigenetic component for the faithful regulation of gene expression. Despite its importance in development and disease, how the molecular agents collectively shape the H3K36me landscape is unclear.

RESULTS: We use mouse mesenchymal stem cells to perturb the H3K36me methyltransferases (K36MTs) and infer the activities of the five most prominent enzymes: SETD2, NSD1, NSD2, NSD3, and ASH1L. We find that H3K36me2 is the most abundant of the three methylation states and is predominantly deposited at intergenic regions by NSD1, and partly by NSD2. In contrast, H3K36me1/3 are most …

Recent Progress In Modeling And Treating Diabetes Using Stem Cell-Derived Islets, Marlie M Maestas, Maggie H Bui, Jeffrey R Millman

2020-Current year OA Pubs

Stem cell-derived islets (SC-islets) offer the potential to be an unlimited source of cells for disease modeling and the treatment of diabetes. SC-islets can be genetically modified, treated with chemical compounds, or differentiated from patient derived stem cells to model diabetes. These models provide insights into disease pathogenesis and vulnerabilities that may be targeted to provide treatment. SC-islets themselves are also being investigated as a cell therapy for diabetes. However, the transplantation process is imperfect; side effects from immunosuppressant use have reduced SC-islet therapeutic potential. Alternative methods to this include encapsulation, use of immunomodulating molecules, and genetic modification of SC-islets. …

Dubai Urban Planning 2040: Resource Requirements In The Urban District 5, Bakhit Alfalasi

Theses

The availability of water, food, energy and air quality resources is compromised by prevailing global issues like environmental stress, climate change, and population growth. This research study details the different requirements for Dubai urban District 5 based on the tenets laid out in the Urban Planning 2040 initiative. The literature review section looks into existing literature on the present state of affairs in the UAE as regards availability of water, food, and energy resources in the country and implications of their production processes on air quality. The Study will employ an exploratory research design, where a systematic review of literature …

Rapid Evolution Of Mitochondrion-Related Genes In Haplodiploid Arthropods, Yiyuan Li, Gregg W C Thomas, Stephen Richards, Robert M Waterhouse, Xin Zhou, Michael E Pfrender

Faculty, Staff and Students Publications

Background: Mitochondrial genes and nuclear genes cooperate closely to maintain the functions of mitochondria, especially in the oxidative phosphorylation (OXPHOS) pathway. However, mitochondrial genes among arthropod lineages have dramatic evolutionary rate differences. Haplodiploid arthropods often show fast-evolving mitochondrial genes. One hypothesis predicts that the small effective population size of haplodiploid species could enhance the effect of genetic drift leading to higher substitution rates in mitochondrial and nuclear genes. Alternatively, positive selection or compensatory changes in nuclear OXPHOS genes could lead to the fast-evolving mitochondrial genes. However, due to the limited number of arthropod genomes, the rates of evolution for nuclear …