Digital Commons Network^™

Harnessing Antagonistic Pleiotropy: Tolc-Dependent Coliphages Can Drive Reduced Antibiotic Resistance In E. Coli, Cooper Mckenna

CMC Senior Theses

The rise of multidrug-resistant (MDR) bacterial pathogens has been a growing concern in healthcare around the world, and bacteriophage (phage) therapy is a promising method to combat MDR infections. One defense mechanism of E. coli against antibiotics is the TolC-AcrAB efflux pump. At the same time, some phages use TolC as a surface receptor to infect the cell. This puts TolC at a crossroads in which it is beneficial to the bacteria to protect against antibiotics but harmful by allowing phage infection, creating the potential for evolutionary trade-offs. Previous research has identified only three TolC-dependent phages and shown phage-resistant E. …

The Future Of Hydropower In Southeast Asia’S Renewable Energy Transition, Olivia Cairns

CMC Senior Theses

This thesis will examine the barriers to implementing hydropower in Southeast Asia and propose responsible solutions. This is necessary because Southeast Asia is not on track to reduce carbon emissions to meet climate change mitigation goals. Coal often outcompetes renewable energy sources as a means of addressing the growing demand for electricity. Many insist that the potential for solar and wind power expansion is high, but often ignore the key problems with these renewables at an industrial scale. Hydroelectric dams face rampant social opposition, mistrust due to policy failures, and a poor reputation for causing social and environmental harm. Yet, …

Unselfing Love: An Analytical Account Of Personal Love And Its Compatibility With Other-Regarding Love, Fangyi(Steve) Wang

CMC Senior Theses

There is a wealth of philosophical literature on love. The two main camps of literature are descriptive and analytical. The former aims to best synthesize and describe how people manifest love in real life, while the latter takes the normative position of evaluating how people should be loving, which normally blends love with a hint of ethical or justice related principles.

One hidden theme that underlies many of the debates on love is the relation to the lover’s self. As this paper will gradually unfold, there are many self-interested reasons disguised behind the philosophical definition of love and the reason …

Dark As Day, Rachel Keady

CMC Senior Theses

“All works, no matter what or by whom painted, are nothing but bagatelles and childish trifles... unless they are made and painted from life, and there can be nothing... better than to follow nature." - Caravaggio

In the fall of 2021, I registered to take “Italian Baroque Art” with Professor Gorse at Pomona College, for the spring of 2022. Professor Faggen, one of my advisors, encouraged this and piqued my interest in the characters of this world. After some casual online research, I was transfixed by one artist in particular: Michelangelo Merisi da Caravaggio. How could I not be struck …

Drone-Based Topographic Monitoring Of The Doheny Beach Replenishment Project As An Alternative To Land-Based Monitoring, Miller Mccraw

CMC Senior Theses

The rising threat of coastal erosion to California’s beach ecosystems and economy has fueled a rise in coastal stabilization projects, including beach replenishment. This process’s potentially adverse impact on a beach’s topography and ecosystem makes post-replenishment monitoring essential for long-term coastline management. Drone-based monitoring presents itself as a faster, cheaper, and safer alternative to traditional post-replenishment monitoring but has little proof of concept as a practical substitute. This study used drone-based photogrammetry coupled with publicly available wave data to track elevation changes at Doheny and San Capistrano Beach after a beach replenishment project to both determine the beach’s resilience to …

Auden: Body/Mind, Basil Lloyd-Moffett

CMC Senior Theses

On one hand Auden appears the most cerebral of poets. It is said that when he arrived at school, aged eight, he professed himself excited to study the different psychological types, and the cryptic verse that was to emerge over a decade later bears the scars of his reading, psychological or otherwise, as clearly as the relentlessly analytical Dichtung und Wahrheit and other late works.Absorbing and repurposing philosophical, psychological, religious, and scientific works was an essential part of his artistic strategy, and led to credible accusations of plagiarism on a number of occasions.And just as his collaborators and friends mocked …

Traditional Chinese Medicine: Employing Integrative Medicine As An Approach To Treat Cancer, Jade Hudson

CMC Senior Theses

This thesis explores the history of Traditional Chinese Medicine (TCM) through its depiction in the four classics of TCM and examines the evolution of the field to date. The five categories of TCM treatments analyzed in this paper include acupuncture, dietary therapy, herbal medicine, moxibustion, and physical exercise. Research highlights significant positive outcomes in cancer patients who incorporate TCM alongside modern cancer treatments, such as reduced nausea, vomiting, fatigue, anorexia, pain, and improvements in quality of life and overall well-being. However, notable risks associated with TCM herbal medicine and moxibustion underscore the need for further research into these practices before …

Views Around The Ring, Patrick Wilson

CMC Senior Theses

My thesis shows the visuals and sound aesthetics of the video game series Halo. For my thesis, I created a 7-and-a-half-minute abstract video containing cutscenes in-game visuals over music from the different games, with an accompanying essay talking about the game and my video. I created this thesis because Halo was and still is a game that has been with me most of my life and I wanted to capture what I thought was important to the game. I achieved this through mixing soundtracks and editing in-game footage and cutscenes together. I learned that creating an abstract video takes a …

The Impact Of The Use Of Mercury In Mining In Colombia, Johan Martinez

CMC Senior Theses

Artisanal and small-scale gold mining is a practice that is common all around the world, especially in Latin America, Africa, and Asia. It is also one of the leading consumers of mercury and leading sources of emissions. Governments have banned the use of mercury completely, including Colombia, but it continues to be used and emitted into the environment. This issue is exacerbated because there is a lack of standards, a lack of research done regarding mercury use in mining, and a complex socio-political history in Colombia. For this reason, this paper seeks to provide a proposed pathway for research to …

Sex Differences In The Effects Of Cortisol On Muscle Characteristics: A Meta-Analysis, Natalie Bitetti

CMC Senior Theses

Background: Cortisol plays a central role in both muscle breakdown and growth. These effects are highly dependent on dose and interactions with other hormones. It is known that men and women show considerable differences in their muscle structure and physiology, which are largely driven by hormonal differences. Cortisol release patterns may also vary between the sexes, with current research showing considerable disagreement. The interplay between cortisol and muscle, two highly variable and sexually dimorphic factors, may prove to have different effects in males versus females.

Objective: This meta-analysis integrates existing research on sex differences in cortisol-muscle physiology with existing research …

Recognition And Domination: A Hegelian Approach To Evolving Gender And Technology Paradigms, Zachary Davis

CMC Senior Theses

This paper aims to develop a strong account of recognition. It begins with a Hegel-inspired account of recognition as a fundamental desire that drives humanity. This account establishes recognition as fundamental to the initial subject formation of independent self-consciousnesses as agents. I offer the lord-bondsman dualism to provide a critique of domination as oppositional to securing the means for recognition. This entails that, as history progresses the world ought to move towards universally adopting mutual recognition relationships without domination. I adopt this goal as an ideal form of recognition. In Chapter 2, I apply this recognitional framework to gender. Through …

The Emergence Of Aedes Aegypti In California: Implications For Ecosystems And Public Health, Jose Ruiz

CMC Senior Theses

This literature review delves into the emergence and impact of Aedes aegypti, the yellow fever mosquito, in Southern California. My investigation begins with an exploration of the physical characteristics, historical background, and its significance as a vector. Notably, Aedes aegypti's historical role as a vector for yellow fever during the 19th century shapes the foundation for understanding its effectiveness in disease transmission and demonstrates the potential of its negative impact on Southern California residents. I examined the habitat preferences and behaviors of Aedes aegypti, emphasizing its adaptability to urban environments and its effect as a daytime feeder with a limited …

Effect Of Dopamine-2-Receptor Manipulation On Social Interaction And Social Decision-Making In Juvenile Fish, Kiren Kanazawa

CMC Senior Theses

Animals interact in intricate social networks. Social behavior is imperative in shaping relationships, in communication, and adapting to changing environments. Despite its profound effects on individual fitness and health, neural-molecular mechanisms behind social behavior and social decision-making continue to be identified. In the present study, we focused on the regulation of social behavior by the Dopamine-2-Receptor (D2R), based on its role in context-dependent social behavior. We used juvenile African cichlid fish, Astatotilapia burtoni, to investigate the effect of dopamine signaling manipulation on their aggressive, territorial, and affiliative behaviors. We hypothesize that D2R manipulation affects social decision-making in juvenile A. burtoni. …

Penelope: Our Cunning Hero, Rossana Leal

CMC Senior Theses

In the literary world, Homer’s Odyssey has served as a fundamental text in the Western canon. It was influential to great writers such as Virgil and Dante, along with being a significant influence in Ancient Greek religion. The subject of both mystery and celebration, Homer remains one of the most prominent authors in literary history. His work has received several interpretations over the years. This thesis takes a feminist and modern approach to the epic poem, focusing on Penelope as the protagonist of the epic and argues for her status as not just an equal partner for her husband, but …

Vision, Love, And The Church: An Analysis Of Key Themes In William Blake's Songs Of Innocence And Of Experience, Anna Tolkien

CMC Senior Theses

This thesis engages in a close reading and interpretation of William Blake’s Songs of Innocence and of Experience. The first chapter examines his visionary imagery, symbolism, and language in The Songs. The second chapter explores his nuanced views on love and sexuality – addressing both a pure, mutually pleasurable love as well as a darker, destructive form of love. Lastly, I discuss his critique of the Church as a repressive and corrupt institution. In each chapter I draw from both Blake’s poetry and visual art. Through this extensive study of Blake’s Songs, I present crucial insights on …

Preservation Through Transformation: An Interpretive Analysis Of Title Vii’S Failure To Secure Remedy For The Wrongs Of Workplace Sexual Harassment, Halle Rudman

CMC Senior Theses

The establishment of Title VII of the Civil Rights Act of 1964 as federal law was a pivotal moment in the pursuit of workplace equality and eradication of discrimination. Unfortunately, the application of Title VII in sexual harassment cases has fallen short of the statute’s noble intentions. In this paper, I argue that the judicial treatment of Title VII has been disloyal to its original purpose, perpetuating systemic inequalities and hindering progress towards gender equality in the workplace. I first establish a framework for the reasonable construction of a statute, drawing on work from various legal theorists to establish three …

How Do Pay Transparency Laws Impact The Gender Pay Gap In The United States?, Kendall Chapko

CMC Senior Theses

After much progress during the late 1900s, the gender pay gap has hardly closed in the last two decades. As policy makers look for new solutions, many governing bodies have turned to pay transparency laws, which make employee salaries transparent to employees. There have been several international studies on this topic, and almost all found that these laws are very effective in decreasing the pay gap. This research is extremely important, as it suggests that these policies push us further towards equality, and makes gender based discrimination less common in the workplace. In my study, I conduct a difference in …

‘Poetry Is Not A Luxury’, Rage Should Not Be A Privilege: The Potential Power Of The ‘Racial Imaginary’, Georgia Mcgovern

CMC Senior Theses

Female rage exists outside of the constructed masculine ideal of anger. To examine female rage, one must analyze the intersections between gender and race. I examine white women's privilege and access to female rage in reality and the fictional world. I explore Black Feminist poetry as a form of storage for rage at gender-based prejudice, racial injustice, and their intersection. Using Myisha Cherry’s term “Lordean Rage”, I recognize this specialized manifestation of female rage as an artistic, intergenerational source of energy for change.

I examine Claudia Rankine’s term “racial imaginary” as an imaginative space in which white people draw lines …

What Are We Most Curious About? Understanding The Relationship Between Curiosity And Marginal Knowledge, Alexis Lee

CMC Senior Theses

There are several competing theories about the relationship between curiosity and metacognitive judgment, or one’s assessment of their own knowledge. Novelty theories say that curiosity is highest for wholly unknown information; complexity theories say that curiosity is highest for moderately unknown information; and the Region of Proximal Learning (RPL) theory says that curiosity is highest for almost-known information. The present study aimed to address how curiosity differs within marginal knowledge (MK), memory content that is available but not accessible, across two experiments. In both experiments, participants responded to 100 short-answer general knowledge questions, selecting a phenomenological category to represent their …

Conjuring The Moon, Ariella Berkowitz

Open Access Theses & Dissertations

Conjuring The Moon wrestles with the question of why we as women still submit to norms created by men who can't possibly understand our reality. Why should we support ideologies that claim to represent us while actively working against us? Why should we conform to a system that positions us as inessential Other? The speaker of this book aspires to liberate herself from such burdens. Conjuring the Moon encapsulates one woman's search for the feminine divine within herself, her religion, and her environment; but as empowering as this search may be, it remains inextricably connected to her social and historical …

Data-Driven Communicative Behaviour Generation: A Survey, Nurziya Oralbayeva, Amir Aly, Anara Sandygulova, Tony Belpaeme

School of Engineering, Computing and Mathematics

The development of data-driven behaviour generating systems has recently become the focus of considerable attention in the fields of human–agent interaction and human–robot interaction. Although rule-based approaches were dominant for years, these proved inflexible and expensive to develop. The difficulty of developing production rules, as well as the need for manual configuration to generate artificial behaviours, places a limit on how complex and diverse rule-based behaviours can be. In contrast, actual human–human interaction data collected using tracking and recording devices makes humanlike multimodal co-speech behaviour generation possible using machine learning and specifically, in recent years, deep learning. This survey provides …

Preliminary Results Of A Study Using Dynamic Angiography In Predicting Progression Or Regression Of Moderate Severity Lesions, Thach Nguyen, Marco Zuin, Pham Tv Le, Vinh Sieu Lam, Hien Q. Nguyen, Hung V. Dang, Huyen K. Huynh, Duc Khiem Ngo, Thinh T. Nguyen, Imran Mihas

School of Medicine Publications

Background: Many patients with stable angina (SA) having moderate 50% lesions could deteriorate or stay stable for a long time. No present techniques nor test could accurately predict the progression to acute coronary syndrome (ACS) or stabilization of these moderate lesions. Based on the fluid dynamic methodology research, could turbulent flow further damage the plaque and rupture its cap? In contrast, could laminar flow delay the progression of the plaque and keep patients stable for a long period of time?

Methods: Patients with stable angina (SA) were admitted to the intermediate care unit and underwent coronary angiography. Patients were selected …

Peripartum Cardiomyopathy; Understanding And Improving Outcomes-A Systematic Review, Shakirat Ganiyu, Taiwo Akeem Lawal, Sarah Petrie

School of Medicine Publications

Background: Peripartum cardiomyopathy (PPCM) presents a significant global health challenge, contributing substantially to maternal morbidity and mortality worldwide. Despite ongoing research efforts, the multifaceted nature of PPCM, encompassing genetic, environmental, and clinical factors, necessitates a comprehensive understanding to improve patient outcomes effectively.

Aims: This systematic review aims to synthesise current knowledge on PPCM aetiology, risk factors, diagnosis, therapeutic interventions, and prognostic indicators, highlighting recent advancements and potential avenues for future research and clinical management. By addressing key aspects such as genetic predispositions, environmental influences, diagnostic strategies, therapeutic modalities, and global disparities, this review seeks to provide insights that can inform …

Protein Subunit Vaccines: Promising Frontiers Against Covid-19, Vivek P. Chavda, Eswara Naga Hanuma Kumar Ghali, Pankti C. Balar, Subhash Chauhan, Nikita Tiwari, Somanshi Shukla, Mansi Athalye, Vandana Bharat Patravale, Vasso Apostolopoulos, Murali Yallapu

School of Medicine Publications

The emergence of COVID-19 has posed an unprecedented global health crisis, challenging the healthcare systems worldwide. Amidst the rapid development of several vaccine formulations, protein subunit vaccines have emerged as a promising approach. This article provides an in-depth evaluation of the role of protein subunit vaccines in the management of COVID-19. Leveraging viral protein fragments, particularly the spike protein from SARS-CoV-2, these vaccines elicit a targeted immune response without the risk of inducing disease. Notably, the robust safety profile of protein subunit vaccines makes them a compelling candidate in the management of COVID-19. Various innovative approaches, including reverse vaccinology, virus …

Beyond Surgery: Navigating Postoperative Care For Cauda Equina Syndrome Through A Scoping Review, Krithika Anil, Sandra Olmesdahl, Jack Read, Sam Hughes, Marcus Drake, Ingrid Hoeritzauer, Julie Woodfield, Holly Roy

School of Health Professions

Objective: Cauda equina syndrome (CES) is a serious neurological injury that can result in permanent disability. Our objective was to review the evidence for rehabilitation strategies for CES in a scoping review.Methods: A scoping review of the literature to identify rehabilitation strategies and their outcomes was performed. The search strategy used was: (Cauda equina syndrome) AND (treatment OR management OR intervention OR physio* OR bladder* OR neuro* OR stem cell OR repair OR rehab*) AND ("post?operat* OR post?surgical OR surgery"). MEDLINE, CINHAL, Prospero, Cochrane, ClinicalTrials.gov, EMBASE, Web of Science, PEDro, and eThos were searched.Results: Eight studies of rehabilitation for CES …

Energy Content Of Acorns Of Shinnery Oak (Quercus Havardii) In The Diet Of Scaled Quail (Callipepla Squamata) In Southeastern New Mexico, J.L. Hunt, M.E. Grilliot, T.L. Best, D. Lozano-Lopez, E.R. Neilson, I.C. Castillo

Journal of the Arkansas Academy of Science

Shinnery oak (Quercus havardii) is a deciduous, low-growing shrubby tree that is a dominant plant in large areas of grassland in western Oklahoma, the Texas Panhandle, and eastern New Mexico. Acorns of the plant are important food items for many wildlife species, including scaled quail (Callipepla squamata), mourning doves (Zenaida macroura), and endangered lesser prairie-chickens (Tympanuchus pallidicinctus). We analyzed the energy content of acorns of shinnery oak obtained from the crops of scaled quail collected from plains-mesa sand-scrub in Lea and Eddy counties, New Mexico. Acorns were removed from crops and dried for 48 hours at 60°C to remove moisture …

Big Fur Secret (1944) By Margaret Wise Brown, Peter Shea

Picture Books

This little-known book by Margaret Wise Brown follows a boy as he watches animals in a zoo, first just observing, then having fantasies about them: of putting squirrels in his pocket, lying down beside the panda, hugging the polar bear. But he always interrupts his fantasy: the squirrel wouldn’t like to be put in a pocket; he knows better than to lie down next to a panda or to hug a polar bear. The Big Fur Secret is importantly about animals, and about zoos, and about the ways people integrate defenseless beings into their projects and plots. But it is …