Digital Commons Network^™

Is Semaglutide The Key To The Fight Against "Globesity"?, Melissa Travelsted, Maire M. Blankenship

International Journal of Faith Community Nursing

The obesity epidemic, referred to as "globesity" by the World Health Organization (WHO) in 2001, remains a critical global health issue with escalating prevalence rates. In 2022, approximately 2.5 billion adults worldwide were overweight, with 890 million classified as obese, highlighting a significant health burden and economic impact. By 2030, projections suggest over one billion individuals globally will be affected by obesity. In the United States, where more than 40% of adults are obese, healthcare costs attributed to obesity-related illnesses exceed $173 billion annually.

Obesity is defined by a body mass index (BMI) of 30 or above and significantly increases …

Unmeasured Confounding In Summary Estimates Of Maternal Periodontitis And Adverse Birth Outcomes: Meta-Analyses Of Observational Studies, May Salama, Abdullah Al-Taiar, Denise Mickenny

Graduate Student Government Association Research Conference

Abstract

Importance Maternal periodontitis has been consistently linked to adverse birth outcomes. However, a causal relationship is not established due to potential unmeasured confounding factors in observational studies and inconclusive results from randomized controlled trials.

Objective To assess the impact of unmeasured confounding factors in meta-analyses examining associations between maternal periodontal disease and preterm birth or low birth weight.

Data Sources PubMed/Medline, the Cochrane database for systematic reviews, Embase, Google Scholar, and a manual search of the reported references between 2002 and 2023.

Study Selection Systematic reviews with meta-analyses of observational studies were included if either preterm birth or low …

Constraining The (Im)Possible: Improvisation And Violence In Rafi Zabor’S The Bear Comes Home, Hannah Ianniello

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

This paper will explore the role of jazz improvisation in the characterization of the protagonist in Rafi Zabor’s 1998 jazz novel, The Bear Comes Home. I suggest that Zabor represents the process of improvisation to not only enhance the enigma of The Bear’s ability as a jazz musician, but also to enhance his capacity towards violence.

Through the exploration of the actual process of improvisation in the research of Paul Berliner, Ingrid Monson and Alyn Shipton, Improvisation in a real jazz context is collaborative and exploratory. However, Zabor, like many other authors (such as Michael Ondaatje, James Baldwin and …

A Representation Of The Normalization Of Multiculturalism And Authentic Language Use In Children’S Animated Bilingual Television Programs, Jordan Carter

Three Minute Thesis (3MT®) at UNI

This study explores the linguistic and cultural practices that are portrayed in bilingual children's animated television programs, Santiago of the Seas and Alma's Way. Discourse analysis focuses on the main characters of each show. The analysis of the first season of each program demonstrates that characters primarily use Spanish to make cultural references, express terms of endearment, and as a way to form relationships between friends and family members. By exploring this linguistic practice of emblematic code-switching together with the representation of cultural practices, the authenticity of these practices utilized within multilingual communities can be evaluated. While previous studies show …

Considering Ethical Questions In (Non)Fiction: Reading And Writing About Graphic Novels, Gene Mcquillan

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Teachers often feature graphic novels in college courses, and recent research notes how these texts can help make the process of reading more engaging as well as more complex. Graphic novels help enhance a variety of “literacies;” they offer bold representations of people dealing with trauma or marginalization; they explore how “texts” can be re-invented; they exemplify how verbal and visual texts are often adapted; they are ideal primers for introducing basic concepts of “post-modernism.” However, two recurring textual complications in graphic novels can pose difficulties for students who are writing about ethical questions. First, graphic novels often present crucial …

Detection Of Pollutants In Soil Using Laser-Induced Breakdown Spectroscopy (Libs), Ekhlas Jabir Mahmood, Mithaq Muter Mehdy Al- Sultani

Al-Bahir

The tremendous development in various industrial and agricultural fields has led to an increase in pollution of soil and water bodies, which has been reflected in the quality of agricultural products and their quantity, as well as the damage that this pollution causes to human health and the growth system of other living organisms. Many soils are polluted with heavy metal elements like lead (Pb), zinc (Zn), cadmium (Cd), chromium (Cr), copper (Cu), iron (Fe), aluminum (Al), and mercury (Hg), which makes the environmental situation more difficult. As part of this sensitive stage, monitoring and analysis have become essential to …

Spartan Daily, November 7, 2024, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2024

Volume 163, Issue 33

Agenda/Program: Frank Reidy Research Center For Bioelectrics Retreat 2024, Frank Reidy Research Center For Bioelectrics, Old Dominion University

2024 Frank Reidy Research Center for Bioelectrics Retreat

Agenda and condensed program for the 2024 Frank Reidy Research Center for Bioelectrics Retreat held on November 7, 2024 at the ODU Priority Club in Norfolk, VA.

A Protocol For Immunostaining Of Macrophages In Whole-Mount Mouse Cornea, Conjunctiva, And Lacrimal Gland, Saleh Alfuraih, Dhruv Patel, Wonsuk Choi, Karthikeyan Ramasamy, Rais Ansari, Ajay Sharma

Pharmacy Faculty Articles and Research

The healthy lacrimal functional unit contains a resident macrophage population. Here, we present a protocol for immunofluorescent staining of macrophage markers, CD11b, F4/80, and CD206, in whole-mount mouse cornea, conjunctiva, and 50-μM-thick lacrimal gland section. We describe steps for dissection, fixation, permeabilization, and blocking. We then detail procedures for the detection and spatial localization of macrophages through immunostaining and confocal imaging. This approach circumvents the need to obtain thin tissue sections and acquire macrophage images from each tissue section.

Human And Social Service Professionals’ Perceptions And Experiences Supporting Human Trafficking Victims And The Role Of Social Capital, Esmilyn Natalie Porter

Walden Dissertations and Doctoral Studies

Human and Social Service Professionals’ Perceptions and Experiences Supporting Human Trafficking Victims and the Role of Social Capital by Esmilyn Natalie Porter (Johnson) MA, National Louis University, 2010 BS, University of Wisconsin-Madison, 1999 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Human and Social Services Walden University November 2024

Human And Social Service Professionals’ Perceptions And Experiences Supporting Human Trafficking Victims And The Role Of Social Capital, Esmilyn Natalie Porter

Walden Dissertations and Doctoral Studies

Human and Social Service Professionals’ Perceptions and Experiences Supporting Human Trafficking Victims and the Role of Social Capital by Esmilyn Natalie Porter (Johnson) MA, National Louis University, 2010 BS, University of Wisconsin-Madison, 1999 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Human and Social Services Walden University November 2024

Biodegradable Polymeric Microspheres For Magnetically Guided Drug Delivery To Tumors, Tyler Payson Green

Theses and Dissertations

This thesis investigates the feasibility of utilizing biodegradable polymeric microspheres loaded with the anticancer drug 5-fluorouracil (5FU) and superparamagnetic iron oxide nanoparticles (SPIONs) to magnetically deliver the cancer therapeutic 5FU to a target tumor in the human body. The primary method of material loading consisted of a w/o/w double emulsion mechanism which 1) loads and protects 5FU in the inner water phase consisting of distilled water and polyvinyl alcohol (PVA), 2) dispersed SPIONs in the biodegradable polymeric organic phase consisting of methylene chloride (MeCl2) for eventual magnetic transport, and 3) suspended these w/o emulsion droplets in an outer aqueous phase …

Curriculum Subcommittee Minutes November 7, 2024, Utah State University

Educational Policies Committee

• Approval of Minutes
• Program Proposals
• Semester Course Approval Reviews
• Other Business
• Adjourn: 3:00pm

Red Snapper Neurocranium, Roman Devlin, Michael A. Birnbaum, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Education Policy Committee Agenda November 07, 2024, Utah State University

Educational Policies Committee

• Approval of Minutes
• Subcommittee Reports
• Other Business
• Adjourn

Curriculum Subcommittee Agenda November 7, 2024, Utah State University

Educational Policies Committee

• Approval of Minutes
• Program Proposals
• Semester Course Approval Reviews
• Other Business
• Adjourn: 3:30pm

Spectator 2024-11-07, Editors Of The Spectator

The Spectator

No abstract provided.

Diverse Genome Structures Among Eukaryotes May Have Arisen In Response To Genetic Conflict, Elinor G. Sterner, Auden Cote-L’Heureux, Xyrus X. Maurer-Alcalá, Laura A. Katz

Biological Sciences: Faculty Publications

In contrast to the typified view of genome cycling only between haploidy and diploidy, there is evidence from across the tree of life of genome dynamics that alter both copy number (i.e. ploidy) and chromosome complements. Here, we highlight examples of such processes, including endoreplication, aneuploidy, inheritance of extrachromosomal DNA, and chromatin extrusion. Synthesizing data on eukaryotic genome dynamics in diverse extant lineages suggests the possibility that such processes were present before the last eukaryotic common ancestor. While present in some prokaryotes, these features appear exaggerated in eukaryotes where they are regulated by eukaryote-specific innovations including the nucleus, complex cytoskeleton, …

Metallomic Approach To Mercury And Selenium In The Liver Tissue Of Psectrogaster Amazonica And Raphiodon Vulpinus From The Brazilian Amazon, Izabela Bataglioli, José Vieira, Joyce Da Siva, Luane Andrade, Victor Faria, Rebeca Corcoba, Ronaldo De Almeida, Luiz Zara, Marília Buzalaf, Jiri Adamec, Pedro Padilha

School of Medicine Faculty Publications

This paper reports the results of a mercury (Hg) and selenium (Se) metallomic study in the liver tissues of Psectrogaster amazonica and Raphiodon vulpinus from the Brazilian Amazon. Two-dimensional electrophoresis, graphite furnace atomic absorption spectrometry, and liquid chromatography-tandem mass spectrometry were performed. Hg and Se determinations allowed the calculation of Hg:Se and Se:Hg molar ratio and Se values for health benefits (Se HBVs). The Se:Hg values were >1 for both fish species, whereas the Se HBVs were >5 for P. amazonica and >10 for R. vulpinus, indicating that both possess Se reserves to control Hg toxicity. The metallomic data allowed …

Mark2 Variants Cause Autism Spectrum Disorder Via The Downregulation Of Wnt/Β-Catenin Signaling Pathway., Maolei Gong, Jiayi Li, Zailong Qin, Matheus Vernet Machado Bressan Wilke, Yijun Liu, Qian Li, Haoran Liu, Chen Liang, Joel A. Morales-Rosado, Ana S A Cohen, Susan S. Hughes, Bonnie Sullivan, Valerie A. Waddell, Marie-José H. Van Den Boogaard, Richard H. Van Jaarsveld, Ellen Van Binsbergen, Koen L. Van Gassen, Tianyun Wang, Susan M. Hiatt, Michelle D. Amaral, Whitley V. Kelley, Jianbo Zhao, Weixing Feng, Changhong Ren, Yazhen Yu, Nicole J. Boczek, Matthew J. Ferber, Carrie Lahner, Sherr Elliott, Yiyan Ruan, Cyril Mignot, Boris Keren, Hua Xie, Xiaoyan Wang, Bernt Popp, Christiane Zweier, Juliette Piard, Christine Coubes, Frederic Tran Mau-Them, Hana Safraou, A Micheil Innes, Julie Gauthier, Jacques L. Michaud, Daniel C. Koboldt, Odent Sylvie, Marjolaine Willems, Wen-Hann Tan, Benjamin Cogne, Claudine Rieubland, Dominique Braun, Scott Douglas Mclean, Konrad Platzer, Pia Zacher, Henry Oppermann, Lucie Evenepoel, Pierre Blanc, Laïla El Khattabi, Neshatul Haque, Nikita R. Dsouza, Michael T. Zimmermann, Raul Urrutia, Eric W. Klee, Yiping Shen, Hongzhen Du, Leonard Rappaport, Chang-Mei Liu, Xiaoli Chen

Manuscripts, Articles, Book Chapters and Other Papers

Microtubule affinity-regulating kinase 2 (MARK2) contributes to establishing neuronal polarity and developing dendritic spines. Although large-scale sequencing studies have associated MARK2 variants with autism spectrum disorder (ASD), the clinical features and variant spectrum in affected individuals with MARK2 variants, early developmental phenotypes in mutant human neurons, and the pathogenic mechanism underlying effects on neuronal development have remained unclear. Here, we report 31 individuals with MARK2 variants and presenting with ASD, other neurodevelopmental disorders, and distinctive facial features. Loss-of-function (LoF) variants predominate (81%) in affected individuals, while computational analysis and in vitro expression assay of missense variants supported the effect of …

The Altered Landscape As Heterotopia, Shane Hulbert, Ioannis Galanopoulos Papavasileiou

All Works

This paper considers the contemporary photographic practices of the authors, aligning their conceptual ideas and working methodology with notions of heterotopia. It argues for a positioning within contemporary altered landscape photography that considers place as a heterotopia, a networked system or process that modifies and makes an alternative ‘territory’. In dialogue with a range of relevant authors and artists, the paper contextualises heterotopia and altered landscape spaces as layers of both cultural and ecological intervention. It asserts that an artist in a state of mobility, transit and movement, can effectively employ notions of heterotopia to inform a creative photographic practice. …

Nanobubble Contrast Enhanced Ultrasound Imaging: A Review, Pinunta Nittayacharn, Felipe M. Berg, Dorian Durig, Agata A. Exner

Faculty Scholarship

Contrast-enhanced ultrasound is currently used worldwide with clinical indications in cardiology and radiology, and it continues to evolve and develop through innovative technological advancements. Clinically utilized contrast agents for ultrasound consist of hydrophobic gas microbubbles stabilized with a biocompatible shell. These agents are used commonly in echocardiography, with emerging applications in cancer diagnosis and therapy. Microbubbles are a blood pool agent with diameters between 1 and 10 μm, which precludes their use in other extravascular applications. To expand the potential use of contrast-enhanced ultrasound beyond intravascular applications, sub-micron agents, often called nanobubbles or ultra-fine bubbles, have recently emerged as a …

University Of Northern Iowa Graduate Studies Fourth Annual Three Minute Thesis® Competition [Program, 2024], University Of Northern Iowa. Graduate Studies.

Three Minute Thesis (3MT®) at UNI Programs

Graduate students engage with audience members regarding their research.

Human And Social Service Professionals’ Perceptions And Experiences Supporting Human Trafficking Victims And The Role Of Social Capital, Esmilyn Natalie Porter

Walden Dissertations and Doctoral Studies

Human and Social Service Professionals’ Perceptions and Experiences Supporting Human Trafficking Victims and the Role of Social Capital by Esmilyn Natalie Porter (Johnson) MA, National Louis University, 2010 BS, University of Wisconsin-Madison, 1999 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Human and Social Services Walden University November 2024

The Abc's Of Gratitude: The Power Of Focusing On The Good, Sharon K. Ferrett

Trade & Scholarly Monographs

Even while struggling with the realities of daily life, you may have a glimpse of wonder that opens your heart and changes everything. Instead of being irritated by small annoyances or wallowing in misery, focus on the good, and your life will be transformed. It sounds too simple, but I have experienced the power of gratitude. Once you make looking for the good a daily habit, your life will be a continual source of thanksgiving. I offer this modest book as a primer to help you find countless opportunities to look for the good and practice gratitude.

Socioecological Factors Influencing The Anticipated Medical Help-Seeking Time For Breast Cancer Among Women In Togo, A Sub-Saharan Country, Komi Blewussi Aheto

Walden Dissertations and Doctoral Studies

Breast cancer remains a leading cause of death in sub-Saharan Africa (SSA). The burden of the disease in the region is partly attributed to delayed health-seeking, resulting in advanced disease presentation, delayed diagnosis, poor outcomes, and low survival. This quantitative cross-sectional study was conducted to investigate the socioecological factors that influence the anticipated medical health-seeking time for women in SSA experiencing breast cancer symptoms. The socioecological model (SEM) theoretical framework guided this study. A questionnaire was used to collect data from randomly selected (N = 343) women aged 18 years and older with no personal or familial history of breast …

Montana Kaimin, November 7, 2024, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Comparing Fermented Food And Vitamin E On Exercise-Mediated Nrf2/Are Activation In Middle-Aged/ Elderly: A Randomized, Double-Blind Clinical Study, Joseph Cervi, Reza Rastmanesh, Amir Moghadam-Ahmadi, Antonio Ayala, Cristiana Aperio, Aldo Lorenzetti, Maki Osato, Francesco Marotta, Antonio Nardin, Fang He

Department of Neuroscience Faculty Papers

Background: There is a compelling need to emphasize the importance of deepening the rationale behind functional foods research in molecular biology. Indeed, establishing stringent criteria to evaluate functional food interventions in disease prevention and as adjunctive therapeutic strategies offers significant opportunities for health promotion. Objective: This study investigated the effects of fermented papaya preparation (FPP®) and vitamin E on gene expression in middle-aged/elderly individuals, leveraging FPP’s established antioxidant and immune-regulatory benefits. Methods: Graded Exercise Walking Test was administered twice weekly for 6 months. Total Antioxidant capacity (TAC) and gene expression (Nrf2, NQO1, HO-1) in PBMC were measured monthly. Results: Throughout …

Kenyon Collegian - November 7, 2024

The Kenyon Collegian

No abstract provided.

Total Retinal Thickness Is An Important Factor In Evaluating Diabetic Retinal Neurodegeneration, Noor-Us-Sabah Ahmad, Kristen Staggers, Kyungmoo Lee, Nitish Mehta, Amitha Domalpally, Benjamin J Frankfort, Yao Liu, Roomasa Channa

Faculty, Staff and Students Publications

OBJECTIVE: Macular retinal nerve fibre layer (mRNFL) and ganglion cell-inner plexiform layer thickness (GC-IPL) measurements are important markers of diabetic retinal neurodegeneration (DRN). In this cross-sectional study, we aimed to quantify the contribution of total retinal thickness (TRT) and other factors in the variation of mRNFL and GC-IPL thickness among participants with diabetes.

METHODS AND ANALYSIS: We used macular-centred spectral domain-optical coherence tomography scans from participants with diabetes in the UK Biobank. Two multiple linear regression models (prior to and after adjusting for TRT) were used to determine factors associated with mRNFL and GC-IPL thicknesses. A p value of less …