Digital Commons Network^™

What Fishing Tackle Should I Bring Today?: Safety Harbor Resource Collection Tools As Adaptations To Aquatic Environments, Richard J. Davis Iii

Graduate Thesis and Dissertation 2023-2024

This thesis reports on the results of research conducted to determine whether technological adaptations to local environmental conditions can be observed through geospatial and artifact analysis of Safety Harbor collections from the Tampa Bay region of Florida. Past artifact and spatial analysis did not take advantage of modern technological advancements when studying how human-environmental interactions can influence certain adaptations to local conditions. In this project, GIS was used to reconstruct local aquatic environmental conditions of waterways adjacent to Safety Harbor sites. New statistical software programs have also proven themselves useful to archaeologists seeking to conduct hypothesis testing of artifact data. …

Three Good Things To Improve Dementia Caregiver Outcomes: Feasibility, Nicole V. Mcclure

Graduate Thesis and Dissertation 2023-2024

The current study investigated the feasibility of utilizing a positive psychology strategy, Three Good Things, for dementia caregivers who at times may be limited in their ability to access resources due to caregiving role demands. The experimental task asked participants to list three things that went well for the day and their role in these events. Participants were randomized into a control or experimental group. The study was conducted on a sample of self-identified dementia caregivers (N = 45) to help reduce negative outcomes such as depression, burden, burnout, and negative affect. Further, variables thought to be influenced by increases …

Effect Of Acetate And Cell Density On External Proton Supply For Chlamydomonas Reinhardtii Biohydrogen Production, Keval V. Patel

Graduate Thesis and Dissertation 2023-2024

Green microalgae can naturally produce renewable hydrogen gas (H₂) in anaerobic environments by expressing hydrogenase enzymes (HydA). However, H₂ production from microalgae remains low and challenging because HydA are only active in low O₂ conditions. One practical strategy for creating an anaerobic environment is by adding acetate which can disrupt the oxygen evolving complex (OEC) causing the microalgae to switch to respiration of acetate until O₂ is completely depleted. However, by disrupting the OEC, a rich source of protons (H⁺) from water splitting is lost. This may make H⁺ into a limiting …

Building Better Homes For Pollinators: How Native Plants Benefit Pollinator Communities In Suburban Landscapes, Mykayla Hagaman

Graduate Thesis and Dissertation 2023-2024

Pollinators provide key ecological services. With one-third of our global food production dependent on pollinators, maintaining healthy pollinator communities is vital. Bees are the most pervasive and effective pollinator species, yet are currently declining worldwide, with the main cause linked to habitat loss. To combat this decline, researchers are turning to suburban landscapes to aid in pollinator conservation. Incorporating native plants into suburban landscapes has been shown to benefit pollinators. However, there is a lack of information on how different landscape designs and growing conditions influence pollinator communities. To better understand whether native plants can effectively improve suburban pollinator habitats, …

Exploring The Benefits Of The Integration Of Xr And Bim For Retrofitting Projects, John Sermarini

Graduate Thesis and Dissertation 2023-2024

Rapidly changing population dynamics and increased energy needs have reduced demand for building renovation in favor of more wasteful complete demolition and reconstruction. This dissertation aims to enhance the accessibility and ease of use of challenging retrofitting methodologies to mitigate adverse effects of urbanization, increasing resource use, and aging building stock within the United States. Retrofitting is a process focused on upgrading a component or feature of a structure that was not initially constructed or manufactured, and it is often done to modernize, restore, or repurpose a structure. These renovations are difficult and costly to plan and implement, frequently contributing …

A Multiscale Meshless Method For Simulating Cardiovascular Flows, Kyle Beggs

Graduate Thesis and Dissertation 2023-2024

The rapid increase in computational power over the last decade has unlocked the possibility of providing patient-specific healthcare via simulation and data assimilation. In the past 2 decades, computational approaches to simulating cardiovascular flows have advanced significantly due to intense research and adoption of methods in medical device companies. A significant source of friction in porting these tools to the hospital and getting in the hands of surgeons is due to the expertise required to handle the geometry pre-processing and meshing of models. Meshless meth- ods reduce the amount of corner cases which makes it easier to develop robust tools …

The Role Of Medical Cannabis Use In Pain, Sleep, And Mental Health Outcomes Among Older Adults, Madison H. Maynard

Graduate Thesis and Dissertation 2023-2024

Older adults represent the fastest growing demographic of cannabis users, and they endorse cannabis use for a variety of reasons including modulation of chronic pain, mental health symptoms, and sleep concerns. Despite escalating patterns of use, current evidence leaves questions of efficacy unanswered among these groups of users. Goals of the present study were to examine the role of medicinal cannabis within subjects at the daily level on the interrelated symptoms of depression, anxiety, sleep, and pain. A final sample of 106 medical cannabis users were recruited nationwide, ranging from 55 to 74 years of age (66.67% female, 82.86% white). …

The Color Of Disease: Race Science, Pandemic Influenza, And The Rise Of Epidemiology In The Segregated South, Andrew Kishuni

Graduate Thesis and Dissertation 2023-2024

This thesis evaluates the relationship between race science and eugenics, statistical epidemiology and Southern public health thought, African American health, and the 1918-1920 influenza pandemic. Historians have neglected the flu as an important epidemiological event in Southern history and historiography. To demonstrate the significance of the flu, this thesis makes several arguments based on research from new qualitative and quantitative evidence. The chief argument is that African Americans suffered disproportionately compared to whites in the South, challenging the consensus that the flu affected both races equally. Segregation did not protect African Americans from the flu. In some cases, African Americans …

Do Generalist-Pollinated Plants Exhibit Pollination Syndromes? Examination Of Floral Size, Shape, Color, And Scent On Pollinator Services To Wild Sunflowers (Helianthus), Charles A. Pitsenberger Ii

Graduate Thesis and Dissertation 2023-2024

Traditional pollination syndromes group angiosperms into categories based on how floral traits impact the functional group of pollinator most associated with those traits. The concept, while well supported for specialist-pollinated plants, is a poor predictor of pollinator identity in generalist systems, such as those common to the family Asteraceae. One potential avenue for future refinement of the concept is the combination of large floral trait datasets, quantitative pollinator data, and phylogenetic comparative methods. Helianthus is a well-studied genus of North American aster whose species include the agriculturally significant H. annuus, which represents the third largest oilseed crop globally. The genus …

Platform-Independent Estimation Of Human Physiological Time From Single Blood Samples, Yitong Huang, Rosemary Braun

Mathematics Sciences: Faculty Publications

Abundant epidemiological evidence links circadian rhythms to human health, from heart disease to neurodegeneration. Accurate determination of an individual's circadian phase is critical for precision diagnostics and personalized timing of therapeutic interventions. To date, however, we still lack an assay for physiological time that is accurate, minimally burdensome to the patient, and readily generalizable to new data. Here, we present TimeMachine, an algorithm to predict the human circadian phase using gene expression in peripheral blood mononuclear cells from a single blood draw. Once trained on data from a single study, we validated the trained predictor against four independent datasets with …

Human Rights & The Rights Of Nature: Friends Or Foes?, Jérémie Gilbert

Fordham International Law Journal

No abstract provided.

Deadly Journeys: Climate Change, U.S. Border Enforcement, And Human Rights, Julia Neusner

Case Western Reserve Journal of International Law

Extreme weather events and slow onset disasters, exacerbated by climate change, are increasingly driving global displacement. As displaced people seek cross-border protection in unprecedented numbers, the United States has responded by tightening border controls and restricting asylum access. These policies have exposed migrants and asylum seekers in transit to greater risks of injury and death due to the impacts of climate change and climate-related disasters. Drawing on legal analysis, historical context, and firsthand interviews with people seeking U.S. asylum, this Article examines the implications of U.S. policies that limit freedom of movement and asylum access. The Article raises critical legal …

Ecocide In War And Peace, From The Air Pollution Consequences Of The War In Ukraine To Japan's Disposal Of Fukushima Water Into The Ocean, Giovanni Chiarini

Case Western Reserve Journal of International Law

This Article will propose and analyze potentially prosecutable cases of alleged global ecocide and propose targeted amendments to Articles 36(3) and (5) of the ICC Rome Statute. These proposed amendments may serve as a blueprint to procedurally ensure environmental expertise at the international judicial level. Ecocide is unfortunately not currently recognized under the Rome Statute. However, certain scholars have suggested defining it as a fifth international crime. This analysis identifies environmental crises, international criminal law expectations and examines the environmental pollution caused by the Russian invasion of Ukraine and the Japanese government’s decision to dispose of radioactive treated water from …

The North Of Ireland During The Interregnum: A Gramcian Analysis Of Power And Crisis, Chris Ó'Rálaigh

Articles

The North of Ireland was induced in to existence over a century ago, yet the polity lacked societal-wide legitimacy. The outbreak of conflict in 1968 signalled the beginning of an interregnal period in which the old order was substantially challenged. Whilst the Good Friday Agreement was idealised as an end to this interregnum, Brexit has re-opened the battle for politico-ideological supremacy. This paper traces the contours of the hegemony-seeking strategies of the various political actors from 1968-present and assesses whether we are in the crucial and final phase of the organic crisis of the North of Ireland.

Cultivating Green Public Spaces And Backyard Gardens Amid Covid-19: An Anthropological Study Of Metro-Orlando Gardeners, Chelsea N. Daws

Graduate Thesis and Dissertation 2023-2024

This dissertation critically analyzes home and community gardens within Metro-Orlando by considering the ways that the COVID-19 pandemic impacts residents' garden participation and access to green public spaces. The study utilizes an ethnographic approach to produce informed understandings of participants' experiences within local gardens, alternative food networks, and community supported agriculture analyzed using Marxian theoretical frameworks. Findings are primarily grounded in qualitative information derived from interviews, participant observation, and photovoice. Data were collected both prior to the global COVID-19 outbreak and over subsequent months of lockdown and public health mitigation measures. Primarily focusing on local community garden organizers, community garden …

Dietary Folate Regulates Organismal Growth And Longevity, Aiman Shahab

Wayne State University Dissertations

Folate (Vitamin B9) is an essential cofactor in one-carbon transfer reactions. It is involved in multiple critical processes including DNA synthesis, DNA methylation, protein synthesis and antioxidant defense mechanisms. Inadequate intake and availability of folate is a known risk factor for several diseases. The effect of folate deficiency in causing adverse health outcome is well documented. Recently, excess folate exposure has been associated with deleterious effects on health in humans and animal models. However, the underlying mechanisms involved in mediating such effects are poorly understood, requiring extensive investigations. This work was conducted to understand the effect of excess folate on …

Density Functional Studies Of Molecular Separation And Charge Transport, Timothy Quainoo

Wayne State University Dissertations

This thesis presents a series of studies which can be grouped majorly into two sections both focusing on the utilization of density functional theory techniques; Molecular electronics and Molecular separation. Molecular electronics has been anticipated to hold a great future as it seeks to apply molecular building blocks in the creation of electronic components. On the other hand, the utilization of mild conditions in chemical processes is geared toward the major goals of green chemistry as it produces less waste and is cost-effective. Thus, this dissertation tackles and answers some of the unanswered questions in literature by using theoretical methods …

Design And Synthesis Of Aminoglycoside-Based Heparan Sulfate Mimetics For Structure-Activity Relationship Studies Of Heparan-Binding Proteins, Joseph Wakpal

Wayne State University Dissertations

Cancer remains a formidable challenge in modern medicine, demanding innovative approaches and treatments. Among the emerging strategies, inhibiting heparanase and fibroblast growth factor 2 (FGF2) has garnered considerable attention in recent years. This dissertation presents a novel approach to designing and synthesizing a diverse library of heparan sulfate (HS) mimetics derived from aminoglycosides to study their binding to two heparin-binding proteins involved in cancer development and metastasis. Heparanase cleaves HS polysaccharide chains in the extracellular matrix (ECM) and is a regulator of aggressive tumor behavior. Clinical studies have illustrated that aberrant heparanase expression correlates with increased tumor size, amplified tumor …

Disease Footprints: Understanding Basic Pathophysiology, Jeff Vasiloff, Md, Mph

OHIO Open Faculty Textbooks

Basic pathophysiology explained by Jeffrey Vasiloff, MD, MPH, Associate Clinical Professor, PA Program; Adjunct Professor, PT Program, College of Health Sciences and Professions, Ohio University Dublin Medical Campus; Physician Consultant: Ohio Association of Physician Assistants; Physician Volunteer: Franklin County & Columbus Medical Reserve Corps; Board Certification: Internal Medicine & Diabetes and Endocrinology.

Nanoscale Characterization Of Interaction Of Nucleosomes With H1 Linker Histone, Ahmed Yesvi Rafa, Shaun Filliaux, Yuri L. Lyubchenko

Journal Articles: Pharmaceutical Sciences

In eukaryotic nuclei, DNA is wrapped around an octamer of core histones to form nucleosomes. H1 binds to the linker DNA of nucleosome to form the chromatosome, the next structural unit of chromatin. Structural features on individual chromatosomes contribute to chromatin structure, but not fully characterized. In addition to canonical nucleosomes composed of two copies each of histones H2A, H2B, H3, and H4 (H3 nucleosomes), centromeres chromatin contain nucleosomes in which H3 is replaced with its analog CENP-A, changing structural properties of CENP-A nucleosomes. Nothing is known about the interaction of H1 with CENP-A nucleosomes. Here we filled this gap …

English Jokes In Azerbaijani: Not Always On The Same Train, İlham Taghiyev, Elmira Jahangirli

Khazar Journal of Humanities and Social Sciences

People do not use humour just for the sake of entertainment, it is a part of everyday communication and information processing system. Since it touches many areas of human life, translators will be tasked with translating jokes at the end of the day. However, translating a joke is not a simple task. Maintaining the spirit of jokes requires translator’s proper and special skills. The main purpose of the paper is to identify which kinds of jokes are translatable or untranslatable from English into Azerbaijani. The researchers made an attempt to classify jokes according to their translatability extent and translation difficulties. …

The History Of -Eer In English: Suffix Competition Or Symbiosis?, Zachary Dukic, Chris C. Palmer

Graduate Publications – English

Ecological models of competition have provided great explanatory power regarding synonymy in derivational morphology. Competition models of this type have certainly shown their utility, as they have demonstrated, among other things, the relevance of frequency measures, productivity, compositionality and analyzability when comparing the development of morphological constructions. There has been less consideration of alternative models that could be used to describe the historical co-development of suffixes that produce words with sometimes similar forms or meanings but are not inevitably or solely in competition. The symbiotic model proposed in this article may help answer larger questions in linguistics, such as how …

Bs Biological Science, Eeob 2024-25, Arkansas State University - Jonesboro

Bachelor of Science and Education

Evolution, Ecology & Organismal Biology

Bs Biological Science, Pre-Veterinary 2024-25, Arkansas State University - Jonesboro

Bachelor of Science and Education

No abstract provided.

Bs Biological Science, Pre-Professional 2024-25, Arkansas State University - Jonesboro

Bachelor of Science and Education

No abstract provided.

Paralog Switching Facilitates Diadromy: Ontogenetic, Microevolutionary And Macroevolutionary Evidence, Rebecca S. Colby, Stephen D. Mccormick, Jonathan P. Velotta, Elizabeth Jockusch, Eric T. Schultz

EEB Articles

Euryhalinity is present in diverse aquatic taxa and requires flexible osmoregulation to field the challenges posed by differing salinities. Na+, K+-ATPase (NKA) is a ubiquitous ion pump in the gills of fishes and, for some species, paralogs of the catalytic -subunit (NKA 1a and NKA 1b) exhibit reciprocal expression between fresh- and seawater, termed paralog-switching. We investigated the expression and evolution of NKA paralogs in Alewife (Alosa pseudoharengus), a euryhaline and migratory fish. Comparisons between landlocked and diadromous life history forms and migrant and pre-migrant ontogenetic stages were used to study shifts in NKA paralog expression related to freshwater or …

A Progressive Judiciary? Judicial Review And National Politics From Reconstruction To The Present, Joshua Braver, Gregory A. Elinson

College of Law Faculty Publications

Within legal academia, the conventional historical narrative is that the Supreme Court has regularly interfered with legislative and executive efforts to protect minority rights and remedy economic inequality. Citing this reactionary tendency, an influential and vocal group of progressive legal scholars have argued that progressives ought to stop defending judicial review and instead devote their energies to eliminating it, or at least aggressively curbing its use. These progressive critics of judicial review (our term) proffer two related historical claims. First, they assert, the Supreme Court has consistently been less progressive than congressional majorities and Presidents. Second, they suggest, even landmark …

Neuroimmune Response And Neurodegeneration In Adolescent Rats Following Binge Alcohol Exposure, Catherine Van Doorn

Theses and Dissertations--Pharmacy

Studies of adolescent drinking show a distinct prevalence of binge drinking, including at extreme levels, and this type of drinking has been identified as increasing risk of developing an Alcohol Use Disorder (AUD). Additionally, females suffer greater levels of harm from binge drinking and AUD and in an abbreviated timeline compared to males. Neuroimmune reactivity, specifically with microglial reactivity following binge drinking, may influence the sex differences seen in negative alcohol-related health disparities.

The first set of experiments sought to examine a marker of microglial reactivity, TSPO, in adolescent females and males and found the sexes displayed different temporal and …

The History Of Physiology And Pharmacology At West Virginia University 1965-2022 A Joint Memoir, Robert L. Goodman, Vince Castranova, John Connors, Jim Culberson, Ping Lee, Mark Reasor, Lauralee Sherwood, Stan Stephens, Stan Yokota

Open Access Books

In this book, the authors update an earlier history of the Department of Physiology at West Virginia University that described its first 100 years. It covers the most recent half-century (1965-2022), a tumultuous time characterized by periods of faculty growth and development of the department’s research and educational programs interspersed with major challenges the department had to overcome. The latter included an autocratic chair who created a hostile work environment, an administrator who favored research centers over departments, and the dissolution of the Department of Pharmacology and Toxicology, which led to the creation of the Physiology and Pharmacology Department. Almost …

Offshore Wind: A Comparative Of The United States And Norway

Fordham Environmental Law Review

No abstract provided.