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Articles 25801 - 25830 of 30684
Full-Text Articles in Entire DC Network
A Rainy Day For Cancer: The Characterization And Utilization Of The Long Non-Coding Rna Lnc-Rainy In The Radiation Response Of Non-Small Cell Lung Cancer, Emily S. Rice
Graduate Theses, Dissertations, and Problem Reports (ETD)
Lung Cancer remains the leading cause of cancer-related deaths worldwide. While important improvements have been made to the treatment of non-small cell lung cancer (NSCLC), treatment resistance is a critical issue facing the majority of patients. Previously, our lab identified a group of long non-coding RNAs (lncRNAs) known as linc-SPRY3 RNAs, expressed on the Y-chromosome, that play a role in radiation sensitivity by decreasing tumor burden in vitro and in vivo after radiation. Through molecular cloning methods and further functional characterization, here we present evidence that the linc-SPRY3 RNAs were originally mischaracterized as individual linc-RNAs but are in fact parts …
Effects Of Probabilistic Win-Paired-Cue Delivery On Loss Trials On Risky Choice In Rats, Connor M. Lambert
Effects Of Probabilistic Win-Paired-Cue Delivery On Loss Trials On Risky Choice In Rats, Connor M. Lambert
Graduate Theses, Dissertations, and Problem Reports (ETD)
Problem gambling, or Gambling Disorder, is a behavioral disorder that affects 2.5% of the U.S. population and can result in detriments to physical, mental, and financial well-being. Electronic gambling machines (e.g., slot machines, video poker, pachinko) may be more addictive than other forms of gambling (e.g., table games, sports betting). Electronic gambling machines present a series of audiovisual stimuli concurrently with winning and some losing outcomes. Previous research in human and non-human animals has found increased levels of risky choice when audiovisual stimuli are presented with wins compared to their absence. The present study was arranged to evaluate how a …
Performance Evaluation Of Composite Utility Structures Under Wildfires And Mitigation Methods, Siddhant Sitoula
Performance Evaluation Of Composite Utility Structures Under Wildfires And Mitigation Methods, Siddhant Sitoula
Graduate Theses, Dissertations, and Problem Reports (ETD)
The Fiber Reinforced Polymer (FRP) composite utility poles and crossarms have been getting wider attention from the utility industries because of their advantages over the traditional wooden, concrete, and steel poles. Wood is vulnerable to fire, rot, and animal damage. Concrete poles are heavier, increasing both transportation and installation costs of the poles, in addition to limited-service life (40-50 years). Similarly, steel poles have durability and safety concerns because of their inherent corrosive nature and conductivity. These disadvantages are significantly reduced by the use of FRP composites in utility structures because of FRP’s strength, specific gravity, flexibility, non-conductivity and durability …
The Role Of Synaptic Zinc Signaling In Excitatory Circuits Of The Mouse Auditory Cortex, Philip T R Bender
The Role Of Synaptic Zinc Signaling In Excitatory Circuits Of The Mouse Auditory Cortex, Philip T R Bender
Graduate Theses, Dissertations, and Problem Reports (ETD)
Synaptic zinc signaling modulates synaptic activity and is present in specific populations of cortical neurons, suggesting that synaptic zinc contributes to the diversity of intracortical synaptic microcircuits and their functional specificity. The pool of chelatable synaptic zinc is controlled by the zinc transport protein ZnT3, a protein which functions by moving free zinc into glutamatergic presynaptic vesicles, from which it is co-released with glutamate during synaptic transmission. Once synaptic zinc is released within the synaptic cleft, it acts on glutamate receptors on the post-synaptic spine, including ionotropic NMDA and AMPA receptors. While the inhibitory function of zinc on NMDA receptors …
Immunomodulation In Osteosarcoma: From Therapy To Diagnostics, Ryan Austin Lacinski
Immunomodulation In Osteosarcoma: From Therapy To Diagnostics, Ryan Austin Lacinski
Graduate Theses, Dissertations, and Problem Reports (ETD)
Osteosarcoma (OS) is a rare pediatric bone malignancy. Those who develop advanced disease, often in the form of metastasis to the lung, experience poor five-year survival rates near approximately 25%. Considering minimal-to-no therapeutic breakthroughs have occurred for treatment of this disease since the 1980s, efforts to develop new therapeutics are underway. The goal of this dissertation was to initiate the preclinical efforts necessary to reinvigorate the use of immunostimulatory cytokine therapy for the treatment of OS and other solid tumors. This effort would not only include the development of the immunotherapeutic known as IL12ns, but also the clinical diagnostic tools …
Implementing Unmanned Aerial Vehicles To Collect Human Gait Data At Distance And Altitude For Identification And Re-Identification, Donn E. Bartram
Implementing Unmanned Aerial Vehicles To Collect Human Gait Data At Distance And Altitude For Identification And Re-Identification, Donn E. Bartram
Graduate Theses, Dissertations, and Problem Reports (ETD)
Gait patterns are a class of biometric information pertaining to the way a person moves and poses. Gait information is unique to each person and can be used to identify and reidentify people. Historically, this task has been achieved through the use of multiple ground-based imaging sensors. However, as Unmanned Aerial Vehicles (UAVs) advance, they present the opportunity to evolve the process of persons identification and re-identification. Collecting human gait data using UAVs at distances ranging from 20m to 500m and altitudes ranging from 0m to 120m is a challenging task. The current biometric data collection methods, primarily designed for …
In Defense Of The “Peculiar Institution”: The Influence Of European Scientific Racism On The Confederacy, Guillem Colom
In Defense Of The “Peculiar Institution”: The Influence Of European Scientific Racism On The Confederacy, Guillem Colom
The Gettysburg Historical Journal
Through the antebellum period and American Civil War, American and European race theorists exchanged ideas through correspondence and scientific explorations asserting the truth of scientific racism. Scientific racist beliefs posited the natural superiority of white people and inferiority of Black people based on what these theorists claimed were innate biological characteristics, and these beliefs served as a critical linkage between Europe and the United States. Utilizing correspondence and journal entries, this paper shows that this exchange of scientific racist ideas significantly influenced the Confederacy’s political thought and policy positions, especially foreign relations, through the Civil War. Through the work of …
Gettysburg Historical Journal 2024
Gettysburg Historical Journal 2024
The Gettysburg Historical Journal
Complete Issue of the Gettysburg Historical Journal 2024
The Power Of Polish: Exploring The Impact Of Nail Adornments On Perceptions Of Attraction, Sara Demichele
The Power Of Polish: Exploring The Impact Of Nail Adornments On Perceptions Of Attraction, Sara Demichele
Honors Theses
Understanding the significance of nail adornments in shaping perceptions of attractiveness and mate value provides insights into human behavior and preferences. In the current investigation, participants rated human nail length and color on physical attractiveness and partner desirability measures. Results revealed significant effects of nail length and color across different demographic groups. Medium-length nails consistently received higher ratings for physical attractiveness, cuteness, and partner desirability compared to short and long nails. White-colored nails were generally rated most attractive, while blue and black nails received the lowest ratings. Additionally, participants reported a moderate association between having manicured nails and feelings of …
2024 Section 5 Revisions: The Voyage Home Or The Wrath Of Khan?, Karl T. Muth, Avery E. Bowen
2024 Section 5 Revisions: The Voyage Home Or The Wrath Of Khan?, Karl T. Muth, Avery E. Bowen
UIC Law Review
No abstract provided.
Retribution Without Rehabilitation: How The “Troubled Teen Industry” Infringes On The Rights Of Privately Placed Youth, Elizabeth Morgan
Retribution Without Rehabilitation: How The “Troubled Teen Industry” Infringes On The Rights Of Privately Placed Youth, Elizabeth Morgan
UIC Law Review
No abstract provided.
Bridging The Gap: Effective Strategies To Engage Emerging Adults In The Church, Tara P. Bulger
Bridging The Gap: Effective Strategies To Engage Emerging Adults In The Church, Tara P. Bulger
All Electronic Theses and Dissertations
This study intended to identify effective strategies to engage emerging adults in the church because research and the researcher’s experience noticed a decline in emerging adults’ attendance in church. This led to the exploration of scripture for biblical themes for reaching the next generation, and a review of current and relevant literature on emerging adulthood, ministry strategies for emerging adults, reasons for their lack of engagement, and intergenerational ministry best practices. A qualitative case study was conducted using a questionnaire and an interview guide. The research used data from 36 emerging adults ages 18-38-years-old, and three senior pastors of intergenerational …
"Other Inhumane Acts Of A Similar Character Intentionally Causing Great Suffering." Does Ecocide Fit Within The Bounds Of Crimes Against Humanity, Amanda Price
Case Western Reserve Journal of International Law
No abstract provided.
Influence Of Human And Viral Il-6 On Kshv Infection In Human Tonsil Lymphocytes, Wajd Zakir
Influence Of Human And Viral Il-6 On Kshv Infection In Human Tonsil Lymphocytes, Wajd Zakir
Pharmaceutical Sciences (MS) Theses
Infection of B cells by the lymphotropic gamma-herpesvirus Kaposi sarcoma-associated herpesvirus (KSHV) causes Multicentric Castleman Disease, Primary Effusion Lymphoma, and the newly-identified inflammatory syndrome designated KICS. Despite proven connections to lymphoproliferative disorders, little is known about how KSHV invades the human immune system or the early events governing infection in B lymphocytes. IL-6 signaling plays a critical role in KSHV-mediated disease, where elevated hIL-6 levels are positively associated with KSHV viral load and disease progression. This dynamic is even more complex due to the co-existence of human IL-6 (hIL6) and KSHV-encoded viral IL-6 (vIL6) in these diseases. Although the impact …
Sychar New Youth Worker, Camp Sychar
Sychar New Youth Worker, Camp Sychar
Annual Report Of The Town Of Lyme, New Hampshire For The Year Ending December 31, 2023., Lyme Town Representatives
Annual Report Of The Town Of Lyme, New Hampshire For The Year Ending December 31, 2023., Lyme Town Representatives
Lyme, NH Annual Reports
This is an annual report containing vital statistics for a town/city in the state of New Hampshire.
Town Of Colebrook Annual Report Year Ending December 31, 2023., Colebrook Town Representatives
Town Of Colebrook Annual Report Year Ending December 31, 2023., Colebrook Town Representatives
Colebrook, NH Annual Reports
This is an annual report containing vital statistics for a town/city in the state of New Hampshire.
Method Of Product Placement In Computer Games. Qualitative Research Amongst Polish Players, Magdalena Hofman-Kohlmeyer
Method Of Product Placement In Computer Games. Qualitative Research Amongst Polish Players, Magdalena Hofman-Kohlmeyer
Journal of Marketing and Consumer Behaviour in Emerging Markets
Nowadays, new technologies enable practitioners to create brand experience in the virtual world of computer games. Marketers use product placement to reach potential and current customers. In the meantime, computer games have become an attractive medium because they attract an increasingly wider audience of different genders and various age groups. Therefore, an important issue is to know and systematize current methods of brand placement in computer games. For the purpose, the author carried out 20 in-depth interviews with players of chosen computer games, Second Life, Euro Truck Simulator 2 and The Sims. According to the analysis, it can be distinguished …
Critical Theories, Justice, And The Rule Of Law, Adam J. Macleod
Critical Theories, Justice, And The Rule Of Law, Adam J. Macleod
Scholarly Articles
An increasing number of legal scholars and activists now identify law as an impediment to justice that must be deconstructed. The deconstructionists tear down the resources we need to sustain the rule of law. And as they deconstruct law, they also deconstruct justice itself. Against deconstructionism, the classical tradition of jurisprudence that gave us our fundamental law affirms that we can know justice and that we can achieve justice through the establishment of law.
That classical tradition made possible the conviction that law is not a mere product of power, as the deconstructionists assert. And that conviction made the rule …
Chaney Step Zero: Judicial Review Of Fec Deadlock Dismissals, Natalie R. Schmidt
Chaney Step Zero: Judicial Review Of Fec Deadlock Dismissals, Natalie R. Schmidt
Scholarly Articles
Partisan polarization has infected our politics at levels not seen in decades. But what happens when the contamination spreads to the institutions responsible for regulating the political process itself? At the Federal Election Commission, nothing. Under the FEC’s governing statute, the Federal Election Campaign Act, any serious action the agency undertakes must be supported by a bipartisan supermajority of commissioners. When the six commissioners fail to reach such consensus—or “deadlock”—due to partisanship or otherwise, nothing happens at all: no investigations, no regulations, no enforcement of federal campaign finance laws. For the first few decades of the FEC’s existence, these deadlocks …
Epr Study Of Irradiated Starch: Induced Radicals And Dose Assessment, Elsayed Salama, Ahmed M. Maghraby, Samy A. Anwer, M. El-Sayed
Epr Study Of Irradiated Starch: Induced Radicals And Dose Assessment, Elsayed Salama, Ahmed M. Maghraby, Samy A. Anwer, M. El-Sayed
Basic Science Engineering
Irradiation of starch is of much importance to get rid of microbes and for disinfection. EPR study of the ionizing radiation-induced radicals can lead to the assessment of radiation doses delivered during irradiation. The EPR spectra properties, microwave power saturation behavior, short- and long-term temporal dependencies, and other significant factors are studied. Response of EPR spectra of irradiated starch over the range (0.5–10 kGy) was investigated. The time dependence study of the radiation-induced signal radicals of starch showed that variation of the EPR signal can be noticed within ±7.7% relative to the average value over 38 days following irradiation. Results …
A Case Study On The Impact Of Intermediate Elementary Teachers’ Pedagogical Content Knowledge And Expectancy Beliefs Of Students On Scaffolding Practices In Mathematics Intervention, Deborah Blakeslee
Graduate Thesis and Dissertation 2023-2024
This study investigated the impact expectancy beliefs had on third through fifth-grade teachers’ instructional teaching practices. These instructional teaching practices included how teachers used their pedagogical content knowledge, specifically their content knowledge for teaching mathematics and formative assessment, to make scaffolding decisions while supporting students in mathematics intervention. The investigation included the analysis of stratified sampling procedures, expectancy beliefs, observations, and self-reported scaffolding ratings. A multiple case study was conducted to understand how four participants, the teachers in the study, expected students to perform in mathematics intervention along with the participants’ pedagogical content knowledge and the impact those beliefs and …
A Causal-Comparative Study Of The Relationship Between School Shooter Typologies, Warning Signs, And Targeted School Violence, German R. Taveras
A Causal-Comparative Study Of The Relationship Between School Shooter Typologies, Warning Signs, And Targeted School Violence, German R. Taveras
Graduate Thesis and Dissertation 2023-2024
This research explores the relationship between school shooter typologies, warning signs, and targeted school violence. The study's independent variables are school shooter typologies and warning signs, while the dependent variable is targeted school violence. The research wants to investigate whether a relationship exists between these variables. The null hypothesis states no relationship exists, while the alternative hypothesis suggests that a relationship exists. The research framework is based on Bronfenbrenner's Ecological System Theory, which helps understand how the environment and social interaction influence a child's development. The theory was influenced by Vygotsky's sociocultural theory—which focuses on the roles of human interactions …
The Role Of Adiponectin In Gustatory Perception Of Fat, Fangjun Lin
The Role Of Adiponectin In Gustatory Perception Of Fat, Fangjun Lin
Graduate Thesis and Dissertation 2023-2024
Taste is a major driving force that influences food choice and dietary intake. Animals' taste abilities vary due to genetics, sex, age, and hormonal status. There is evidence that several appetite-regulating hormones can modulate gustatory detection of fat, and this hormonal modulation of fat taste likely influences food palatability and selection, thereby altering fat intake. Adiponectin is a key metabolic hormone predominantly released from adipose tissue, which enhances insulin sensitivity and stimulates glucose and fatty acid metabolism. Adiponectin receptors are highly expressed in the taste system, indicating that adiponectin signaling may play an important role in the modulation of gustatory …
Sexual Assault Victimization In Virtual Worlds, Narim Lee
Sexual Assault Victimization In Virtual Worlds, Narim Lee
Graduate Thesis and Dissertation 2023-2024
The current dissertation investigated sexual assault victimization in virtual worlds – environments, where individuals engage through avatars, offering a deep level of immersion and interactivity. As the usage of these virtual spaces grows, so does the concern for negative experiences that mirror the sexual assault encountered in the physical world. Despite this, there is a notable gap in the quantitative analysis of virtual sexual assault (VSA) victimization. This research aimed to fill this void by exploring the prevalence of VSA victimization over the previous year and identifying potential predictors of VSA victimization through the lens of cyberlifestyle-routine activity theory. To …
Evidence Of Positive Associations Between Intertidal Shoreline And Subtidal Seagrass Communities In A Subtropical Ecotone, Gabriel Benson
Evidence Of Positive Associations Between Intertidal Shoreline And Subtidal Seagrass Communities In A Subtropical Ecotone, Gabriel Benson
Graduate Thesis and Dissertation 2023-2024
Fringing seagrass beds are important components of coastal ecotones. Their association with shoreline morphology and shoreline restoration, however, is poorly understood. We combined GIS analyses with field-based monitoring to better understand intra-ecotone associations between shorelines and fringing seagrass beds. Using GIS analyses of aerial imagery, shoreline characterization models, and seagrass coverage models, the relationship between shoreline morphology, erosion, and fringing seagrass persistence was examined in Mosquito Lagoon, FL between 2011 and 2021. For the field-based portion of the study, fringing seagrass beds growing adjacent to restored, living shoreline segments were monitored throughout the 2023 growing season (March – November). All …
Climate Change And Coastal Development Impacts On Oyster Abundances In Mosquito Lagoon, Fl, Emily Suchonic
Climate Change And Coastal Development Impacts On Oyster Abundances In Mosquito Lagoon, Fl, Emily Suchonic
Graduate Thesis and Dissertation 2023-2024
Live eastern oyster (Crassostrea virginica) reefs have declined by 62.6% in Mosquito Lagoon (ML) along the eastern Florida coast since 1943. While this species creates reefs by successive generations of oysters recruiting to conspecific shells, C. virginica can also attach to non-reef substrates including mangrove roots and armoring (e.g., seawalls), which may help counteract reef habitat loss. In recent decades, warmer winters have enabled red (Rhizophora mangle) and black (Avicennia germinans) mangrove expansion in subtropical salt marshes and temperate estuaries where oyster reefs occur. Additionally, 11.8% of ML's shorelines have been armored as of …
What Fishing Tackle Should I Bring Today?: Safety Harbor Resource Collection Tools As Adaptations To Aquatic Environments, Richard J. Davis Iii
What Fishing Tackle Should I Bring Today?: Safety Harbor Resource Collection Tools As Adaptations To Aquatic Environments, Richard J. Davis Iii
Graduate Thesis and Dissertation 2023-2024
This thesis reports on the results of research conducted to determine whether technological adaptations to local environmental conditions can be observed through geospatial and artifact analysis of Safety Harbor collections from the Tampa Bay region of Florida. Past artifact and spatial analysis did not take advantage of modern technological advancements when studying how human-environmental interactions can influence certain adaptations to local conditions. In this project, GIS was used to reconstruct local aquatic environmental conditions of waterways adjacent to Safety Harbor sites. New statistical software programs have also proven themselves useful to archaeologists seeking to conduct hypothesis testing of artifact data. …