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Neuro-Immune Regulation Of Feeding Behavior And Alcohol Intoxication In Caenorhabditis Elegans, Kamya Kiranbhai Shah

Theses, Dissertations and Culminating Projects

Alcohol use disorder (AUD) and obesity are major public health concerns, contributing to more than 28 million deaths annually. Despite extensive research, the mechanisms underlying excessive alcohol and food consumption remain incompletely understood. Emerging evidence suggests that neuro-immune crosstalk plays a pivotal role in feeding and alcohol-induced behaviors, with inflammation as a key pathological hallmark. Toll-like receptors (TLRs), traditionally recognized for their role in innate immunity, have recently been implicated in modulating neural responses to ethanol. However, the mechanisms of how TLR signaling influences feeding and alcohol-related behaviors remain largely unknown. To address this gap, we leveraged Caenorhabditis elegans (C. …

Life Cycle Analysis Of Cosmetic Products -- Assessing Environmental Sustainability And Potential Impacts, Karina Magro Machado

Theses, Dissertations and Culminating Projects

The cosmetic industry has a significant environmental footprint due to its reliance on water, energy, petrochemical-derived ingredients, and plastic-based packaging. This study performs a cradle-to-grave Life Cycle Analysis (LCA) to evaluate the environmental impacts of three cosmetic products: CeraVe Daily Moisturizing Lotion, bareMinerals Gen Nude Powder Blush, and Gillette Foamy Regular Shave Cream. The analysis was conducted using OpenLCA software and free databases, modeling each product across raw materials, packaging, manufacturing, transportation, use and end-of-life phases. The results showed that the shave cream had the highest environmental burden to three out of the four categories, especially in consumption and carbon …

Tracking Fall Migration With The Motus Wildlife Tracking System: The Fate Of Window-Struck And Captive-Raised Passerines, Cailin O'Connor

Theses, Dissertations and Culminating Projects

Many species of North American passerines migrate along the Atlantic flyway in the fall to reach winter habitats in the southeastern United States, the Caribbean, and Central and South America. Birds face many perils along their journeys including window strikes, which kill over one billion birds per year in the United States alone. Some birds survive the impact and may continue their migration. These birds may suffer delayed mortality or show aberrant migration due to injuries. This research seeks to understand if window-struck birds that initially survive bird-building collisions survive into the future and, if so, if they migrate effectively. …

Ce 625 Syllabus: Career Development & Appraisal, Madeline Mcrae-Vinzant

Counselor Education Syllabi

This course provides students with the basic theories, counseling techniques, and assessment tools used in career counseling.

Ce 611 Syllabus: Development Over The Lifespan, Anquinetta V. Calhoun

Counselor Education Syllabi

This purpose of this course is to promote students' thinking and learning about human growth adaption, and change throughout the lifespan.

The Monsters Are Due On Hillside Avenue: Paul Robeson And The Racialization Of The Peekskill Riots Of 1949, Joshua Dellacruz

History Honors Program

On August 27, 1949, a burning cross pierced the night sky in the quiet hills of Westchester County. As Howard Fast later recounted in Peekskill USA: There was a moment of silent cessation, and one of the men leaped up on the truck and cried, 'A cross is burning!' We could only see the glare, but the symbolic meaning was not lost upon us. In the sweet land the movement had been rounded out; the burning cross, the symbol of all that is rotten and evil in our land had blessed us. Our night was complete and we could do …

Women In The Environmental Movement: An Examination Of Maternalistic Rhetoric And Its Relationship To Modern Environmentalism In The 20th Century, Danielle Howie

History Honors Program

From 1942 to 1953, the Hooker Chemical Company decided that an abandoned canal in Niagara Falls was the perfect place to dump 22,000 tons of toxic chemical waste, a common disposal practice that was largely unregulated by the local government. The company covered the 16 acres of hazardous waste with clay and sold it to the Niagara Falls Board of Education in 1953 for one dollar. With a warning included in the property deed that mentioned the presence of chemical waste, the company was excluded from all future liability.2 In the decades to follow, a suburban community would flower around …

Iran-Contra And The Memory Of Vietnam: Human Rights, Covert Operations, And The National Security Council, Matthew Sarcinella

History Honors Program

In December of 1972, President Richard Nixon ordered the bombing of North Vietnam, beginning on December 18th and lasting until the 30th. During this period 20,000 tons of bombs were dropped, resulting in the deaths of thousands of Vietnamese. The bombings would soon be known as the “12 Days of Christmas.” Major General Richard Secord, “master of covert operations” sat back and watched as North Vietnam was nearly destroyed. There was nothing that Vietnam could do to combat the U.S. military. Being in Secord’s position, he understood better than anyone that this was far more than a mere phenomenon. For …

Symptomatic Treatment Of Cannabis Withdrawal Syndrome: A Review Of The Existing Literature, Aria Sen, Dale Shober

Rowan-Virtua Research Day

Despite its public reputation as a recreational substance that does not cause physical withdrawal symptoms, cannabis withdrawal syndrome (CWS) was added to the DSM-5 in 2013. Existing research would suggest that almost half of regular cannabis users will experience symptoms such as mood symptoms, insomnia, and gastrointestinal distress. For more than 20 years, the rates of cannabis use have continued to trend upward due to expanding legislation on the recreational use of marijuana. Currently, there are no FDA approved treatments for CWS. Considering this trend, the lack of a well-formed treatment protocol for CWS will have a growing impact on …

Volatile Anesthetic Exposure During Organogenesis (Weeks 6-9): Implications For Fetal Brain Development, Cheryce Daniel, Kylon Coombs

Rowan-Virtua Research Day

Organogenesis, particularly during gestational weeks 6 through 9, represent a critical window for fetal brain development. During this period, neurogenesis, neural tube closure and synaptic organization are actively occurring. Disruption of these processes, especially from exogenous agents, can result in lasting developmental consequences.

The U.S Food and Drug Administration has issued warnings regarding the use of anesthetic agents such as isoflurane, sevoflurane, and desflurane. Noting the potential risk of neurotoxic effects on the developing brain. This warning is particularly highlighted when administered drugs are present for long periods of time or during repeated procedures. The goal of this literature review …

A Better Road To Recovery- Effectiveness Of Osteopathic Manipulative Treatment Compared To Conventional Methods On Post-Concussion Patients, Joliana H. Eskandar

Rowan-Virtua Research Day

Background:

Concussion, a form of traumatic brain injury, often presents with sleep disturbances, headache, confusion, and memory impairment. Current treatment includes reduced screen time, physical activity, and increased rest. For decades, these treatment options have demonstrated improvement in symptoms. Recently, there is growing interest in whether using osteopathic manipulative treatment (OMT) to target structural dysfunctions is more effective. This review compares OMT to conventional treatment methods in post-concussion patients.

Methods:

This literature review uses data from clinical trials, randomized controlled trials, observational studies, and case reports within the past 10-15 years. It includes adolescents, adults, elderly, athletes, and non-athletes while …

Dabigatran Reduced Acute Microgliosis In A Mouse Model With Tbi, Nicholas R. Eltman, Rashmeena Abbasi, Mary C. Kosciuk, Syed Ahmed, Jose L. Pascual, Randel L. Swanson, Nimish K. Acharya

Rowan-Virtua Research Day

Objective:

The study objective was to investigate the acute anti-inflammatory effects of dabigatran in a preclinical mouse controlled cortical impact (CCI) model of severe traumatic brain injury (TBI).

Design

Mice were separated into three groups: controlled cortical impact (CCI) with dabigatran (drug treatment, n=5), CCI with saline (positive control, n=5), and sham CCI without saline or dabigatran (negative control, n=3). Dabigatran (80mg/kg) or saline was administered orally at 2, 10, 18, 26, 34, and 42 hours following experimental CCI in the drug treatment or positive control groups, respectively. Animals in the negative control group received sham CCI only. 48h following …

The Use Of Glp-1 Agonists In Alcohol Use Disorder And Reducing Alcohol Consumption: A Scoping Review, Alec Birnbaum, Yashas Sattur, Akash Patel

Rowan-Virtua Research Day

Alcohol use disorder (AUD) reigns as one of the most pressing issues in the United States with high rates of complications, morbidity, and mortality. Recent studies have exhibited the potential for Glucagon-Like Peptide-1 (GLP-1) agonists to decrease alcohol cravings or alcohol-related adverse events through human and animal studies via reward and satiety signaling pathways. To investigate the ability of GLP-1 agonists to decrease alcohol use, alcohol cravings, and alcohol-related adverse events, this study conducted a scoping review of the current literature to uncover the potential benefit of GLP-1 agonists in patients with AUD. A systematic search across 6 databases was …

Proceedings Of Eksig Conference 2025: Data As Experiential Knowledge And Embodied Processes, Mary Karyda, Damla Çay, Ágnes Karolina Bakk, Renáta Dezső, Jessica Hemmings, Nithikul Nimkulrat

DRS Conference Volumes

No abstract provided.

Creative Brief For Wk Kellogg's Co, Sarah K. Johnson

Marketing Undergraduate Honors Theses

In recent years, cereal, the once classic and essential breakfast food has been losing its market share and overall sales in the breakfast category. WK Kellogg’s cereal brands include Frosted Flakes, Froot Loops, Frosted Mini Wheats, Special K, Rice Krispies, Raisin Bran, Corn Flakes, and more, yet their sales have been falling. They now face a challenge, as consumers become more cost and health conscious, how can cereal be made fun again? What ways can they engage with new audiences and further excite current customers? After conducting research, I have developed a creative brief and strategic pitch that include solutions …

Effects Of The Non-Stimulant Norepinephrine Reuptake Inhibitor, Atomoxetine, On Cognitive Flexibility In Healthy Adult Long-Evans Rats, Noah A. Ivak, Samantha Walkow, Christopher Knapp, Eleni Papadopoulos, Barry D Waterhouse, Rachel L Navarra

Rowan-Virtua Research Day

Executive function is the control of multiple higher order cognitive processes that include attention, working memory, and cognitive flexibility. Cognitive flexibility is the ability to shift behavioral strategies

in response to changing environmental demands and task complexity. This cognitive modality is often impaired in many neuropsychiatric disorders like attention deficit hyperactivity disorder (ADHD). Deficits in cognitive flexibility are associated with dysregulation of the catecholamines, norepinephrine (NE) and dopamine (DA) within the prefrontal cortex (PFC). Atomoxetine (ATX), a non-stimulant NE reuptake inhibitor, elevates levels of NE and DA in the PFC by inhibiting the norepinephrine transporter (NET). ATX is used to …

Accelerated Tumor Growth And Lymphatic Spread Of Transplantable Melanomas In Tumor Necrosis Factor(Tnf)-Transgenic Mice, Catherine F. Alapatt, Robert Hughes, Roger Sheffmaker, Gillian Mcguire, Daniel Deegan, Igor Kuzin, Andrea Bottaro

Rowan-Virtua Research Day

Melanoma is the fifth most common cancer among American adults, with significant morbidity and mortality at 5 years remaining >60% for patients with stage IV disease. The malignancy is due to the transformation of melanocytes, with one of the major risk factors being ultraviolet light exposure. Although as many as one in five human cancers have been linked to chronic inflammation, the role of inflammatory signals in melanoma growth and metastasis remains poorly understood.

Tumor necrosis factor (TNF)-transgenic (TNFtg) mice are a well-established model of chronic systemic inflammation, with involvement of joints and other organ systems. To assess the effect …

Frequency Modulation Of Deep Brain Stimulation Targeting The Periaqueductal Gray: Effects On Pain Perception And Autonomic Regulation, Jack Hennen, Avneet Chawla, Jared Garfinkle, Wen Hao Luo

Rowan-Virtua Research Day

Introduction:

The periaqueductal gray (PAG) is a midbrain structure, and effective target for deep brain stimulation (DBS), involved in the modulation of a multitude of sensory and autonomic processes. It has distinct functional columnar organization, with each column playing its own role in alteration of the body’s ability to respond to pain and stressful stimuli.

Background:

Research regarding the effects of DBS on the PAG has shown the four main subregions of the PAG: the dorsomedial PAG (dmPAG), dorsolateral PAG (dlPAG), lateral PAG (lPAG), and ventrolateral PAG(vlPAG), produce various physiologic outputs when stimulated. These outputs are region and frequency dependent. …

Photodynamic Therapy Vs. 5-Fluorouracil For Field-Directed Treatment Of Actinic Keratosis: A Comparative Literature Review, Bhumik Patel

Rowan-Virtua Research Day

BACKGROUND: Actinic keratosis (AK) is a common precancerous skin condition arising from chronic UV exposure and often involves field cancerization, where visible lesions coexist with subclinical damage. Effective field-directed treatments are critical for preventing progression to squamous cell carcinoma.

HYPOTHESIS: Photodynamic Therapy (PDT) may offer superior efficacy, cosmetic outcomes, and patient adherence compared to topical 5-Fluorouracil (5-FU), despite its higher cost and clinical setting requirement.

METHODS: This literature review analyzed peer-reviewed studies from 2015–2025 comparing PDT and 5-FU for field-directed AK treatment. Outcomes assessed included lesion clearance, recurrence, tolerability, adherence, cost, and patient satisfaction.

RESULTS: PDT demonstrated high clearance rates …

Chemical Exposures In Utero: Phthalates And Congenital Heart Defects, Demi Poulathas

Rowan-Virtua Research Day

Background: Congenital heart defects (CHDs) are the most common type of birth defect. Approximately 80% of CHDs have unknown causes, and phthalates may play a contributing role. Phthalates are ubiquitous environmental chemicals used as plasticizers in a wide range of products, including cosmetics and electronic devices. After entering the body, phthalates bind to the progesterone receptor, which is necessary for fetal development. While multiple studies have explored environmental factors in CHD development, few have examined the effects of phthalates on CHDs in humans. Methods: A literature review was conducted to investigate the relationship between parental occupational phthalate exposure and the …

Mechanisms Mediating The Protective Effects Of Caffeine On Alzheimer’S Disease Progression, Jessica Ivanov, Malky Bernat, Joshua Drawbaugh, Jeremy Mehta, Namira Rahmani, Saikumar Thellapally

Rowan-Virtua Research Day

Background: This review aims to examine the molecular mechanisms through which caffeine may exert neuroprotective effects against Alzheimer’s Disease (AD).

Methods: A literature review was done across PubMed and Embase to identify studies between 2000 and 2024, exploring the mechanism behind caffeine’s effects on AD. The criteria focused on peer-reviewed articles involving human or animal models. Information was gathered on study design, participant characteristics, caffeine consumption, proposed mechanisms, and effects on cognition.

Results: The studies support caffeine's potential as a therapeutic, neuromodulator against AD through six mechanisms: inhibition of adenosine A2A receptors, decreased amyloid-beta production and aggregation, promotion of amyloid …

Assessing The Efficacy Of Prolonged Doxycycline Pep Use In High-Risk Populations For Sti Prevention, Lam Doan, Pearl Joslyn, Lizann Sung, Timothy Breiner, Sarah Marotta, Shikhar Rastogi

Rowan-Virtua Research Day

First recommended in October 2022, doxycycline post-exposure prophylaxis (DoxyPEP) has been increasingly used as a treatment for multiple sexually transmitted infections (STIs). To evaluate the efficacy of prolonged DoxyPEP use in high risk populations - men who have sex with men (MSM) and transgender women - for STIs, different sources addressing various aspects of DoxyPEP, its efficacy in STI prevention, and the potential consequences of its widespread use in terms of antimicrobial resistance were examined. Across 9 studies, DoxyPEP was found to decrease the incidence of bacterial STIs, specifically, syphilis, chlamydia, and gonorrhea with varying efficacy, especially for gonorrhea. Furthermore, …

Systematic Review And Meta-Analysis Examining If Hyperplasia Occurs In Humans In Response To Resistance Exercise, Hitesh Gowda, Scott Dankel, Harshal Parmar, Nicholas Barton

Rowan-Virtua Research Day

Background: It is commonly believed that resistance exercise in humans induces muscle growth primarily via muscle hypertrophy, but there is some debate as to whether muscle hyperplasia occurs. The purpose of this meta-analysis was to quantitively assess whether the presence of muscle hyperplasia occurs in humans performing resistance training.

Methods: Medline, Scopus, and Web of Science were searched on May 17, 2024. Studies that assessed muscle fiber number pre and post resistance training were included in a three-level random effects model to assess changes in muscle fiber number.

Results: A total of 11 studies met the search criteria, with all …

Her Hideous Progeny: Frankenstein'S Legacy, Adaptability, And Contemporary Prominence To Critical Story Telling, Ryan Penske

English (MA) Theses

This thesis situates the narrative of Frankenstein by Mary Shelley with two contemporary adaptations Get Out (2017) by Jordan Peele and Poor Things (2023) by Yorgos Lanthimos. The original 1818 Frankenstein text is composed of different discourses about race, gender, monstrosity, and what it means to be an abject other. As a text full of critical discourse, it has reached great popular culture legacy and has become adapted numerous times over the past two centuries. This thesis explores and acknowledges instances where the text has been adapted and applied to harmful discourses, such as British Prime Minister George Canning’s use …

Nahua Wrap-Skirt From Acatlán, Guerrero, Mexico, Brianda Gonzalez

Department of Anthropology

This piece discusses the techniques used to create an embroidered Nahua wrap-skirt, specifically from Acatlán, Guerrero, Mexico, and the function that is typically attributed to it. In addition to discussing the function and technique, this piece also discusses three main contextual points about the textile, including the role of gender, labor/ class/economy, and globalization. The goal of this piece is to provide researchers with a better understanding of not only the technical process behind creating this skirt, but also to provide an overview of different points that are relevant to the skirt's function and its journey through both time, and …

I Pray To Colors, Jane Damon

Calliope

No abstract provided.

In Plain Sight Mural, Mahnoor Mamood

Calliope

No abstract provided.

Evaluating Cannabigerol As A Therapeutic Agent In Non-Alcoholic Fatty Liver Disease, Michael J. Viereckl

Master's Theses

Non-Alcoholic Fatty Liver Disease (NAFLD) is a prolific disease worldwide, with rising incidence and limited treatment options. The disease is progressive, what begins as simple lipid congestion within the cells of the liver eventually leads to incitement of inflammatory reactions and destruction of the liver which can further develop into cancer. Epidemiological data suggests that Cannabis use is associated with reduced incidence of NAFLD, and relatively recent changes in the plants legal status now affords us with the opportunity to investigate unstudied cannabinoids in the context of NAFLD. Further, growing popularity of these bioactive compounds as supplements warrants investigation into …

Idiopathic Sudden Sensorineural Hearing Loss: Need For Patient-Focused Care, Sarah M. Clarkson

Doctoral Scholarly Projects & Capstones

Sudden sensorineural hearing loss is an acute auditory condition marked by the rapid onset of hearing loss, often without an identifiable cause, termed idiopathic sudden sensorineural hearing loss. The estimated incidence of sudden sensorineural hearing loss is 5 to 20 per 100,000 adults. Anatomy and physiology of the ear highlights the important mechanisms in the ear that are involved in sudden sensorineural hearing loss. Including the type of hearing loss, (sensorineural), and the importance of the cochlear blood supply. The anatomy and physiology of the ear is the foundation for understanding the pathophysiology and various potential mechanisms, including vascular compromise, …

Becoming Sephardic: Historical Consciousness And Emergent Ethnoreligious Identification In New Mexico, Sarah Leiter

Anthropology ETDs

In recent years, an increasing number of Hispanic Catholic New Mexicans have discovered that they descend from Iberian Jewish victims of the Spanish Inquisition. For some, this new information has prompted them to identify as Jewish in various ways. However, many have faced considerable difficulty in gaining recognition of their newfound ethnoreligious ancestry among family members, normative Jewish communities, and the Spanish and Portuguese governments that offered reparative citizenship to Sephardic (Iberian Jewish) descendants. In this ethnographic context, this dissertation explores how shifting understandings of religious identity and ancestral pasts affect identification practices in the present. Drawing on theoretical analyses …