Digital Commons Network^™

Remote Teleassessment And Telerehabilitation Of A Comprehensive Exercise Training Protocol For Older Adults: Design And Methodology Of A Usability Protocol, Savitha Subramaniam, Spyros Kitsiou, Tanvi Bhatt

Internet Journal of Allied Health Sciences and Practice

ABSTRACT

Purpose: The design, usability, safety, and feasibility of a telehealth protocol comprising teleassessment and tele rehabilitation to evaluate and improve physical and cognitive function among older adults was assessed. Methods: Healthy older adults (n=23) participated in a pre-post tele-assessment of a 4-week (3 sessions/week) telerehabilitation session. Tele-assessment was performed to evaluate balance, gait function, and cognition. Tele-rehabilitation sessions comprised of balance games, dancing, dual-tasking, yoga, and tai-chi exercises. Results: There were no adverse events reported to indicate concerns with the safety of the current telehealth protocol. Conclusion: The proposed telehealth protocol to assess and improve physical and cognitive function …

A Model For Teaching Financial Literacy In A Doctor Of Physical Therapy Program Using The Five Stages Of Career Development, Madeline Ratoza, Rupal Patel, Fabian Bizama, F Scott Feil

Internet Journal of Allied Health Sciences and Practice

Purpose: The cost of higher education programs across allied health disciplines have increased substantially in recent years while salaries have remained relatively stagnant. The result of which is an increase in debt burden for graduates of allied health professional programs. One possible intervention to improve the experience of graduates is to improve financial literacy; however, research on the effectiveness of financial literacy education in higher education is scant. Therefore, the purpose of this study was to understand the effectiveness of a financial literacy and career planning seminar in a Doctor of Physical Therapy (DPT) program. Specifically, this study aimed to …

Stressed Fracture: The Relationship Between Coping Strategies And Workload In Secondary School Athletic Trainers, Andrew Gallucci, Katherine M. Lee, Leslie W. Oglesby, Anna Porter, Leslee Funderburk, Jeff S. Forsse

Internet Journal of Allied Health Sciences and Practice

Purpose: The work environment for an athletic trainer (AT) working in a secondary school is typified by heavy workloads and job-related stress. Occupational stress can have negative effects on productivity, absenteeism, employee turnover, and quality of life. Research suggests that personal and situational factors can influence the coping process adopted by an individual. The approach-avoidance framework suggests that people cope with a stressor by either attempting to reduce it or removing oneself from that stressor. Previous research on other healthcare professionals suggested that use of avoidance coping was correlated with higher levels of job stress and those who perceived greater …

How Traits Of Emotional Intelligence Affect Perceived Stress In Entry-Level Doctor Of Occupational Therapy Students, Heidi A. Carpenter, Chelsey Edwards, Scott Richardson

Internet Journal of Allied Health Sciences and Practice

Purpose: Students in an entry-level Doctor of Occupational Therapy (OTD) programs are subject to high levels of stress and emotional burnout. Effective management of stress impacts life satisfaction and academic performance. Emotional intelligence (EI) has been shown to relate to lower stress levels in allied health students. Despite this, little has been done to investigate the emotional demands of an occupational therapy education. Methods: Participants were a convenience sample of 51 entry-level Doctor of Occupational Therapy Students recruited from the Southwest and Midwest cohorts of an OTD program. The participants were surveyed approximately 30 days after beginning their semester curriculum. …

The Effectiveness Of Student-Driven Pro Bono Physical Therapy Services On Self-Reported Outcomes Of Community-Dwelling Adults With Musculoskeletal Conditions, Elise Harris, Tamara Hefferon, Peyton Oules, Katherine Sarnacki, Benjamin Galaviz, Jake Robert Gaston

Internet Journal of Allied Health Sciences and Practice

Purpose: Student-driven pro bono clinics provide a profound clinical education experience for health professional students while serving members of the community. Currently, there is little research on how the pro-bono clinic impacts the community members involved. The purpose of this study was to examine outcomes following discharge from a pro bono clinic held through an entry-level physical therapy program. Methods: Forty-one volunteer community members, 19 males (M) (46.3%) and 22 females (F) (53.6%), participated in this study. Ages ranged from 20-90 years, with a mean age of 41(17) years. Each community member completed the Wong-Baker FACES Pain Rating Scale (WBFS), …

Working Hours, Sleep, And Burnout Among Athletic Trainers Employed In College Athletics: A Cross-Sectional Study, Stephanie M. Singe, Catherine G. Mydosh, Alexandrya Cairns, Christianne M. Eason

Internet Journal of Allied Health Sciences and Practice

Purpose: Burnout continues to be an important concern for athletic trainers working in the collegiate sport setting. The purpose of the study was to examine the relationships between working hours, sleep, and burnout among athletic trainers providing patient care in the collegiate setting. Methods: A web-based (Qualtrics, Provo, UT) cross-sectional study using a self-reported questionnaire was used to collect demographics and data on working hours, sleep, and burnout. The Copenhagen Burnout Inventory (CBI) was used to determine burnout. Results: The mean age of our participants (n=1006) was 33 ∓ 9 years; 37.6% (n=378) were male, 61.5% (619), and 1.1% …

A Model For Professionalism Evaluation: Using The Rise Assessment Tool Across Dpt Didactic And Integrated Clinical Education, Rebecca Edgeworth Ditwiler, Laura Lee Swisher, Barbara Reddien Wagner, Stephanie Ann Anderson

Internet Journal of Allied Health Sciences and Practice

Purpose: There are limited options for professionalism evaluation during short term clinical experiences in physical therapy education. The purpose of this report is to describe the development of a new assessment tool (RISE) [Respect for Others, Integrity & Compliance, Self-Awareness & Commitment to Development, and Engagement & Work Ethic] as part of a longitudinal professional development model in the DPT didactic curriculum (RISE-SA) and integrated clinical education (RISE-CI). Primary goals of the RISE were to clearly define evaluation criteria, offer quick formative feedback, promote communication between clinical and academic faculty, and create objective professionalism …

Hearing Loss As A Risk Factor For Cognitive Decline In The Elderly: A Rapid Review, Natalie Large, Nannette Nicholson

Internet Journal of Allied Health Sciences and Practice

Purpose: The aim of this rapid review was to identify and evaluate evidence exploring hearing loss as a risk factor for cognitive decline in the elderly population. Methods: A literature search was performed in three databases: CINAHL, Cochrane Central, and PubMed. The PRISMA template was used to record the search and selection process. Search criteria included older adults aged 65 and up with diagnosed or self-reported hearing loss and no previous diagnosis of dementia or Alzheimer’s disease. Participants were excluded if they had been diagnosed with dementia or tested for it before the study began. Hearing loss was categorized using …

Effects Of A Dynamic Arm Stabilizer On Varus Elbow Torque, Arm Speed, And Velocity In Collegiate Baseball Players: A Pilot Study, Andrew Cage, Laurel Trail, Lynzi Warner, Brandon J. Warner

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this study was to assess the effect a dynamic arm stabilizer had on varus elbow torque, arm speed, and throw velocity during baseball throwing. Methods: 8 collegiate baseball players (age= 20 ± 1 years, height= 183.5 ± 6.5 cm, weight= 85.6 ± 7.7 kg) participated in this study. Participants were randomly assigned to throw their first set of 25 throws at 90 feet wearing a dynamic arm stabilizer or throw their second set of 25 throws at 90 feet not wearing a dynamic arm stabilizer. After completing the first set of throws, the participants threw a …

Title: Assessment Of Student Perception Regarding Clinical Training In Undergraduate Dental Programs Using Clin Ed Iq., Sanaa Ahmed, Samira Adnan, Syed Mahmood Haider

Internet Journal of Allied Health Sciences and Practice

Purpose. Clinical training is essential part of the dental curriculum. Both clinical environment and Teachers are essential factors which affect the acquired clinical skills. The objective was to assess the perceptions of dental students regarding their clinical training. Methods. This mixed method study using Clin Ed IQ questionnaire was conducted on Dental students graduating from both Private and Public sector institutes of Karachi. The questionnaire had four sections, the first three based on various aspect of clinical training, with responses based on 5-point Likert scale. Section four had open-ended items about dental curriculum. Results. For responses of 220 participants related …

Utilization Of The Canadian Interprofessional Health Collaborative As An Evaluation Framework For Student Participation In A Community-Engaged Project, Elise Boyle, Benjamin Feiten, Amy A. Abbott, Sadie Schultes, Shelby Hoffmann, Emily Knezevich, Vanessa D. Jewell

Internet Journal of Allied Health Sciences and Practice

Purpose: Interprofessional education is a foundational component of many health professions educational programs as it contributes to the goals of the Quadruple Aim by prioritizing collaborative and streamlined quality healthcare. Furthermore, student engagement in interprofessional educational activities provides opportunities to better understand their own and others’ health profession disciplines. The purpose of this project was to utilize Canadian Interprofessional Health Collaborative (CIHC) to evaluate a framework for student engagement in a community-engaged project focused on reducing barriers to care in people living with type 1 diabetes in rural communities. Methods: As members of an interprofessional, type 1 diabetes, community-engaged research …

Progressive Glenohumeral Instability In An Adolescent Ice Hockey Athlete: A Case Report, Kelsey J. Robinson, Jennifer Austin

Internet Journal of Allied Health Sciences and Practice

This case follows the injury presentation of a 16-year-old male, right-hand dominant, left-hand shot, Tier I ice hockey player who sustained an initial injury to the left shoulder from a body check during a game. What follows is a cascade of events involving 3 injuries and 2 surgeries, highlighting the complex and potentially compounding nature of instability. Glenohumeral (GH) instability among collision athletes is rare in the absence of contributing genetic conditions or a dislocation or subluxation event. Authors discuss the key concepts related to the diagnosis and management of GH instability, with a special emphasis on subtle injury indicators …

Perceptions Of Incivility Among Students And Faculty In Entry-Level Health Professional Programs, Kristen Barta, Germaine Ferreira, Manuel A. Domenech

Internet Journal of Allied Health Sciences and Practice

Purpose: Online education is growing in popularity but has the potential to result in cyber incivility leading to disruptions in the learning environment. There is little known about the differences in attitudes between students and faculty in the online learning experience regarding cyber civility. The purpose of this study was to analytically measure student and faculty perceptions and attitudes of cyber incivility. Methods: A convenience sample of 180 (34 faculty and 146 students) participants from a health care university were recruited. A 27-item survey was given to record the perceptions of students and faculty on issues of cyber civility. An …

Student Athletic Therapists' Knowledge Of Pain-Relieving Medications: A Nationwide Study, Jackie Vandertuin, Dalya Abdulla, Stephanie Lowther, Joshua Collins

Internet Journal of Allied Health Sciences and Practice

Purpose: Misuse of pain-relieving medications (PRMs), including opioids, is high among injured athletes. Athletes are increasingly relying on PRMs and as a result, it is likely that student athletic therapists (SATs) have managed athletes who have misused PRMs and may have potentially missed important symptoms placing athletes in harm. While dispensing PRMs is not within the scope of practice of the SAT, recognition and referral are. Previous research has found that SATs feel ill prepared to recognize PRM misuse and feel tremendous pressure to provide correct health information to the athlete. The purpose of this study was to expand on …

Association Of The G>A (Rs6265) Polymorphism In The Brain Derived Neurotrophic Factor Gene (Bdnf) With Post-Training Changes In Caucasian Women, Katarzyna Świtała, Agata Leońska-Duniec, Monika Michałowska-Sawczyn, Andrzej Brodkiewicz, Kinga Łosińska, Anna Grzywacz

Baltic Journal of Health and Physical Activity

The brain-derived neurotrophic factor (BDNF) rs6265 (G196A; Val66Met) polymorphism has been associated with obesity and type 2 diabetes, with contradictory results involving either A or G as the risk allele. The main aim of this study was to examine whether the BDNF rs6265 polymorphism would influence the efficiency of a training program. An additional aim was to determine whether selected polymorphism can be used as a genetic marker for obesity-related parameters. We studied the genotype distribution in a group of 160 Caucasian females in whom body mass and composition parameters, lipid profile, and glucose levels were measured before …

Corrigendum To "Ssr-Based Molecular Diagnosis For Taiwan Tea Cultivars And Its Application In Identifying Cultivar Composition Of The Processed Tea"

Journal of Food and Drug Analysis

No abstract provided.

Acknowledgment Of Reviewers

Journal of Food and Drug Analysis

No abstract provided.

Application Of The Us Food And Drug Administration’S Sentinel Routine Querying Tools To The Taiwan Sentinel Data Model-Formatted National Health Insurance Research Database, Fang-Ju Lin, Ling-Ya Huang, Chi-Chuan Wang, Sengwee Toh

Journal of Food and Drug Analysis

The U.S. Food and Drug Administration’s Sentinel System is a leading distributed data network for drug safety surveillance in the world. The National Health Insurance Research Database (NHIRD) in Taiwan was converted into the Taiwan Sentinel Data Model (TSDM) based on the Sentinel Common Data Model (SCDM) version 6.0.2. The goal of this study was to investigate the feasibility of applying the same study designs, analytic choices, and analytic tools as used by the U.S. Sentinel System to examine the same drug-outcome associations in the TSDM-formatted NHIRD. Four known drug-outcome associations previously examined by the U.S. Sentinel System were selected …

Isolation Of Glp-1 Enhancing Indolizidine Alkaloids From Boehmeria Formosana, Ching-Yi Lu, Zheng-Ying Huang, Meng-Chin Chen, Hui-Kang Liu, Shoei-Sheng Lee, Chia-Chuan Chang

Journal of Food and Drug Analysis

Boehmeria formosana, with its related species, demonstrates anti-glycemic effect, inhibition of HBV production, anti-cancer activities, etc. Some indolizidine alkaloids from the same genus are bioactive but sensitive to light. To overcome this problem and obtain more phenanthroindolizidine alkaloids, isolation was performed in darkness, yielding 10 new indolizidine alkaloids and 17 known compounds. Among them, seven enhanced glucagon-like receptor 1 (GLP-1) activity at 50 mM, especially 14 and 6 (3.5- and 2.3-fold than the negative control). This procedure yielded bioactive indolizidine alkaloids with novel structures.

An Integrated Strategy To Evaluate Active Substances Of Astragali Radix-Carthami Flos Combination On The Treatment Of Cerebral Ischemia Reperfusion Injury Based On Tqsm Polypharmacokinetics And Pharmacodynamics, Qiang Zeng, Chang Li, Shouchao Xu, Yu He

Journal of Food and Drug Analysis

As a classic herb pair, Astragali Radix-Carthami Flos (AR-CF) has revealed good biological activity in the treatment of cerebral ischemia/reperfusion injury (CI/RI), which remained to be further clarified together with the underlying efficacy related compounds for material basis. In this study, the nine formulations were obtained by L₉(3⁴) orthogonal array design of four active fractions (saponin and flavonoid extracted from AR, safflower yellow and safflower red extracted from CF). The concentrations of eleven components and the levels of four biochemical indicators in rat plasma were continuously detected after intragastric administration of nine formulations, respectively. The collected …

Cryptocaryone Induces Apoptosis In Human Hepatocellular Carcinoma Cells By Inhibiting Aerobic Glycolysis Through Akt And C-Src Signaling Pathways, Chen-Lin Yu, Yu-Wei Lai, Jih-Jung Chen, Jie-Jen Lee, Tsung-Hsien Chou, Chen-Chen Huang, Shih-Chia Liu, Guang-Wei Chen, Chung‐Hsin Tsai, Shih-Wei Wang

Journal of Food and Drug Analysis

Hepatocellular carcinoma (HCC) is the most common form of liver cancer, with the second highest mortality rate in all cancer. Energy reprogramming is one of the hallmarks of cancer, and emerging evidence showed that targeting glycolysis is a promising strategy for HCC treatment. Cryptocaryone has been shown to display promising anti-cancer activity against numerous types of cancer. Previous study also indicated that cryptocaryone induces cytotoxicity by inhibiting glucose transport in cancer cells, but the detailed mechanism still needs to be elucidated. Therefore, this study aimed to investigate the relationship between the anti-cancer effect and glycolytic metabolism of cryptocaryone in human …

Dehulled Adlay (Coix Lachryma-Jobi L.) Ameliorates Hepatic Gluconeogenesis And Steatosis In Streptozotocin/High-Fat Diet-Induced Diabetic Rats, Shing-Hwa Liu, Wan-Hsin Wu, Huei-Ping Tzeng, Wenchang Chiang, Meng-Tsan Chiang

Journal of Food and Drug Analysis

Adlay (Coix lachryma-jobi L.) is a traditional Chinese herbal medicine with various biological activities. We investigated the anti-diabetic effects of different parts of adlay seeds, including polished adlay (PA), adlay bran (AB) and dehulled adlay (DA) in a streptozotocin (STZ)/high fat diet (HFD) diabetic rat model (DM). DM rats supplemented with or without PA (43%), AB (3%), or DA (46%) diet for 8 weeks. The plasma glucose and insulin levels and the insulin resistance index (HOMA-IR) were increased in DM group; among the three adlay diets, DA has the best effects attenuating all of these alterations in DM …

Biological And Clinical Significance Of The Age-Rage Axis In The Aggressiveness And Prognosis Of Prostate Cancer, Shih-Hong Khoo, Pei-Ru Wu, Kun-Tu Yeh, Shih-Lan Hsu, Chi-Hao Wu

Journal of Food and Drug Analysis

Dietary factors and chronic hyperglycemia are linked to the formation of advanced glycation end products (AGEs) and prostate cancer (PCa) risk. The activation of the receptor for AGEs (RAGE) acts as a bridge between various RAGE ligands and certain malignancies. This study showed that the interaction of AGEs and RAGE promoted PCa cell proliferation, invasion, and autophagy-mediated survival in response to chemotherapeutic agents. RAGE-overexpressed PCa cells underwent epithelial-mesenchymal transition and showed increased cancer stem cell-like properties. In mouse xenograft models, RAGE-overexpressed cells showed more substantial tumorigenic capacity than parental cells, whereas RAGE knockdown decreased tumorigenicity. The clinical data validated a …

Steamed Daylily Flower (Hemerocallis Fulva L.) Protected Cardiac And Hepatic Cells Against Ethanol Induced Apoptotic And Oxidative Damage, Sheng-Lei Yan, Wen-Tzu Wu, Mei-Chin Mong, Mei-Chin Yin

Journal of Food and Drug Analysis

Our previous study examined the phytochemical composition and bio-activities of raw daylily flower (Hemerocallis fulva L.). However, this plant food is usually served via heat process such as cooking in a soup. This study aimed to investigate the phytochemical profile and biofunctions of steamed daylily flower (SDF). The content of total phenolic acids, total flavonoids, total carotenoids, total anthocyanins and total triterpenoids in SDF aqueous extract was assessed. Normal cardiac and hepatic cells, H9c2 and L-02 cells, were used to evaluate the protective effects of SDF against ethanol. SDF concentrations of 0.25%, 0.5%, and 1% were applied to treat …

Analysis And Identification Of Phenolic Compounds With Antiproliferative Activity From Chinese Olive (Canarium Album L.) Fruit Extract By Hplc-Dad-Spe-Tt-Nmr, Yu-Te Yeh, Chien-Kuang Chen, Yi-Chun Liao, Shoei-Sheng Lee, Shu-Chen Hsieh

Journal of Food and Drug Analysis

Chinese olives (Canarium album L.) are rich in phenolic compounds, exhibiting a broad spectrum of potential clinical applications. This study is the first report on the isolation and elucidation of bioactive compounds with high antiproliferative activity from the ethyl acetate fraction of a Chinese olive fruit methanolic extract (CO-EtOAc). We used the WST-1 assay to determine which subfractions of CO-EtOAc had significant antiproliferative activity using the murine colon cancer cell line CT26. Subsequently, the functional compounds were characterized by the hyphenated technique and high-performance liquid chromatography-diode array detector-solid phase extraction-transfer tube-nuclear magnetic resonance (HPLC-DAD-SPE-TT-NMR). Thirteen phenolic constituents were identified …

Glycine-Rich Peptides From Fermented Chenopodium Formosanum Sprout As An Antioxidant To Modulate The Oxidative Stress, Chen-Che Hsieh, Shu-Han Yu, Hsing-Chun Kuo, Darin Khumsupan, Hsiao-Chu Huang, Yu-Wei Liou, Chen-Yu Kao, Szu-Chuan Shen, Kuan-Chen Cheng

Journal of Food and Drug Analysis

Rhizopus oligosporus was utilized in the solid-state fermentation of Chenopodium formosanum sprouts (FCS) in a bioreactor. Subsequently, the antioxidant activity of food proteins derived from FCS was investigated. Results showed that glycine-rich peptide (GGGGGKP, G-rich peptide), identified from the < 2 kDa FCS proteins, had antioxidant values. According to SwissADME, AllerTOP, ToxinPred, and BIOPEP-UWM analyses, G-rich peptide was identified as safe, non-toxic, and non-allergenic. Afterward, the peptide was examined using in silico and in vitro studies to evaluate its potential alleviating oxidative stress caused by particulate matter. This study proposed plausible mechanisms that involve the binding of G-rich peptide which inhibited phosphorylation of the v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) subunit on NF-κB pathway. The inhibition then resulted in down regulation of NF-κB transcription and genetic expression of inflammatory …

Investigation Of Microwave Extraction Of Red Cabbage And Its Neurotherapeutic Potential, Halil Koyu, Serdar Demir, Mehmet Zeki Haznedaroglu

Journal of Food and Drug Analysis

In the pursuit of bioactive compounds with health benefits from food and medicinal plants, optimization of process to reduce solvent, raw material, energy and time consumption has been a valuable research objective. Sustainable management and efficient use of natural resources are of critical importance for sustainability goals. In this manner, microwave extraction of red cabbage which has been a mass cultivated plant for food purposes, was optimized for maximizing acetylcholinesterase, butyrylcholinesterase, tyrosinase inhibitory activity and bioactive content. Quantitative analysis of total phenol, flavonoid and anthocyanin content were performed using spectrophotometry and UPLC-DAD-ESI-MS/MS. Optimum conditions were determined as 600 W, 100% …

Abundance Of Prevotella Copri In Gut Microbiota Is Inversely Related To A Healthy Diet In Patients With Type 2 Diabetes, Chih-Yiu Tsai, Po-Yu Liu, Meng-Chuan Huang, Chiao-I Chang, Hsin-Yun Chen, Yu-Hsien Chou, Chi-Neu Tsai, Chia-Hung Lin

Journal of Food and Drug Analysis

While the gut microbiota is known to be influenced by habitual food intake, this relationship is seldom explored in type 2 diabetes patients. This study aims to investigate the relationship between dietary patterns and gut microbial species abundance in 113 type 2 diabetes patients (mean age, 58 years; body mass index, 29.1; glycohemoglobin [HbA1c], 8.1%). We analyzed the gut microbiota using 16S amplicon sequencing, and all patients were catogorized into either the Bacteroides enterotype (57.5%, n = 65) or the Prevotella enterotype (42.5%, n = 48) using the partitioning around medoids clustering algorithm, based on the most representative genera. Patients …

Therapeutic Effects Of Orally Administration Of Viable And Inactivated Probiotic Strains Against Murine Urinary Tract Infection, Vo Thi Hong Van, Zhen-Shu Liu, Yueh Jen Hsieh, Wei-Chen Shiu, Bo-Yuan Chen, Yu-We Ku, Po-Wen Chen

Journal of Food and Drug Analysis

Urinary tract infections (UTIs) are highly prevalent bacterial infections that pose significant health risks. Specific probiotic strains have been recommended for UTI control and management of antibiotic resistance. Otherwise, paraprobiotics, defined as inactivated probiotic cells, offer potential advantages by minimizing risks associated with live microorganisms. However, the effectiveness of heat-killed probiotic strains against UTIs remains uncertain. Additionally, lactoferrin (LF), an iron-binding glycoprotein, exhibits immunomodulatory, antimicrobial, and anti-inflammatory properties. Recently, we had developed recombinant LF-expression probiotics, which can display considerate antibacterial activities against select food-borne pathogens in vitro. Thus, the present study aimed to evaluate the antibacterial activities of heat-killed natural …

Recent Advances In Combined Avant-Garde Technologies (Thermal-Thermal, Non-Thermal-Non-Thermal, And Thermal-Non-Thermal Matrix) To Extract Polyphenols From Agro Byproducts, Isaac Duah Boateng

Journal of Food and Drug Analysis

Because food byproducts (waste) are rich in phytoconstituents, valorizing them is crucial for global food security. However, conventional extraction (CE), including decoction, maceration, Soxhlet, etc., for agro byproducts’ polyphenol extraction are time-consuming and rely significantly on vast volumes of potentially aggressive solvents. Hence, Avant-garde extraction technologies, including non-thermal (high hydrostatic pressure (HHPE), pulsed-electric field (PEF), high voltage electrical discharges (HVED), etc.) and thermal extraction (supercritical fluid (SCF), subcritical water extraction (SWE), microwave-assisted extraction (MAE), etc.), as well as their thermal combinations (SCF-PLE, SCCO2-SWE, SCCO2-MAE, etc.), non-thermal combinations (HHPE+UAE, PEF+UAE, HVED+UAE, etc.) and combined thermal-non-thermal (MAE-UAE, etc.) are increasingly replacing CE. …