Digital Commons Network^™

Gatekeeping At Bio, Daniel A Gorelick

Faculty, Staff and Students Publications

No abstract provided.

“I Felt We Were Actually Learning Things, Then Applying Them” Students’ Perceptions Of A Service-Learning Course, Christina Gipson, Jessica A. Mutchler, Arshpreet Kaur Mallhi, Amanda Lambert

Health Sciences & Kinesiology: Faculty Publications

Academic journals continue to produce articles that highlight record levels of student disengagement and lack of motivation. Faculty have been encouraged to use high impact, active learning strategies to increase student engagement and success (Patrick et al., 2016). One technique, service learning, allows students to become active learners through applying learned skills and theory from the classroom to community settings (Connolly, et al., 2017). The purpose of this study was to highlight students’ perceptions and experiences through three semester-long service-learning courses where students provided a fitness and mindfulness program to local teachers to help them address stressors. Undergraduate sports management …

Digital Literacy For Older Adult English Language Learners, Talley Caruso

Master's Projects and Capstones

When essential services transition to digital platforms, individuals with limited digital proficiency, immigrant English Language Learners (ELLs), and older adults aged 65 and above face challenges accessing these resources, leading to potential exclusion.

The COVID-19 pandemic accelerated the shift to online interactions and services due to lockdown measures, reducing face-to-face interactions. This sudden transition left individuals without digital skills unable to access healthcare, essential services, and maintain connections with their support networks. Addressing this issue presents an opportunity to promote inclusivity, empowerment, and community engagement through targeted digital literacy training.

Digital literacy encompasses the ability to navigate technology such as …

A Qualitative Exploration Of The Lived Experiences Of Graduate Students With Histories Of Mental Health Diagnoses Navigating Clinical Psychology Doctoral Programs, Hannah Flanery

Dissertations and Theses

In general, graduate students experience unhealthy stress levels throughout their graduate careers. Clinical psychology doctoral students experience additional stressors related to intensive training in providing psychological-related services to clients. There is a gap in the literature in understanding how clinical psychology doctoral students with a personal history of mental health effectively navigate highly stressful graduate programs. This dissertation explored the experiences of clinical psychology Ph.D. students who 1) have a history of mental health diagnoses and 2) experience current psychological distress as they manage educational/training demands and administer psychological interventions to clients. A phenomenological qualitative approach was utilized to fully …

A Quality Improvement Project On Anxiety Management Before Ketamine-Assisted Psychotherapy, Kiera Paulo

Doctor of Nursing Practice (DNP) Projects

Background: This Quality Improvement project sought to determine if a brief progressive muscle relaxation (PMR) session could decrease patient anxiety before receiving intramuscular (IM) injections for ketamine-assisted therapy. Problem: The Kerstin Helgason, NP clinic does ketamine-assisted therapy, and many patients express anxiety beforehand, either due to a fear of needles or nerves surrounding the medication treatment. Intervention: This project implemented a brief progressive muscle relaxation therapy for patients with anxiety before receiving their IM injection. Measures: The patient’s anxiety levels were measured before and after the PMR therapy using a five-point Likert scale ranging from none to very severe. Results: …

Optimal Control Of Ion Exchange Process For Chromate Removal And Protein A Chromatography For Antibody Extraction, Fadi Ghanem

Theses and Dissertations

Ion exchange resins are widely used in the extraction of hazardous chemicals as well as the recovery of precious molecules. Therefore, an early breakthrough from the resin system can lead to toxic compounds affecting the drinking water quality or inefficient use of costly resins. Hence, accurate modeling of the ion exchange process and control strategy can enable decisions that assist in avoiding leakage when facing fluctuations in the inlet contaminant concentrations. In this work, the ion exchange process is modeled via the method of moments where the system uncertainties are captured via stochastic modeling using Ito processes. The flow rate …

Diversity In Post-Brexit Britain: Looking At Its Current State And Future Trends, Camilla Witmer

The Crown: Syracuse Honors Research Journal

No abstract provided.

Dirty Jersey: Geographies Of Contaminated Sites And Race, Ananya Chandra

The Crown: Syracuse Honors Research Journal

No abstract provided.

Making Mathematics Meaningful: How Learning About Local Social Injustices Develops Undergraduate Students’ Identity, Intellect, Skill, And Criticality, Emanuel Boutros, Qiong Wu, Hanyi Xu, Nicole Fonger

The Crown: Syracuse Honors Research Journal

No abstract provided.

Unfair To Compare: Why Assumptions Shouldn’T Authorize Discourse, Gianna Rullo

The Crown: Syracuse Honors Research Journal

No abstract provided.

Hydrofoil: The History Of A Cold War Weapon-Turned Personal Recreation Gadget, Yida "Rick" Li

The Crown: Syracuse Honors Research Journal

No abstract provided.

The Crown, Complete Issue - V1, The Crown

The Crown: Syracuse Honors Research Journal

No abstract provided.

Castor Oil Polyol-Based Adhesives With Additional Crosslinker For Improvement In Mechanical And Thermal Properties., Yash Desai

Electronic Theses & Dissertations

Polyurethanes (PU) have been promising polymeric materials with many applications, including adhesives. Projecting an estimated revenue from 42.8 billion $ in 2021 to 61.5 billion $ by 2026. However, a large number of PU adhesives are sourced from petroleum products. Therefore, to lower the dependence on non-renewable resources and provide sustainable and affordable alternatives. In this work will synthesize bio-based adhesives of polyurethane from modified castor oil-based polyol. Generally, polyurethane reaction depends on the properties of polyol and isocyanates. The most important aspect of these reactions is the OH number of the polyol, which is responsible for the crosslinking and …

Usp1 Expression Driven By Ews::Fli1 Dually Promotes Ewing Sarcoma Cell Survival By Mitigating The Replication Stress Response And Stabilizing Survivin, Halle Mallard

Theses & Dissertations

Ewing sarcoma (EWS) is a malignant pediatric bone cancer. EWS express a fusion oncogene resulting from the reciprocal translocation of EWSR1 an ETS transcription factor. In most EWS tumors, this occurs with FLI1, creating the EWS::FLI1 fusion oncogene which encodes an aberrant transcription factor. Independent of its transcriptional activity, EWS::FLI1 deregulates other cellular processes driving oncogenesis. For cases with a single, localized tumor, roughly 80% of patients remain event-free after five years. Disease dissemination is a problem – about 25% of patients have metastatic disease at diagnosis. Long-term survival for these patients is less than 40%. Presently, no second line …

Paper-Based Ratiometric Sensor Array For Pathogenic Bacterial Species Identification, Aayushi Laliwala

Theses & Dissertations

Bacterial infections are the leading cause of mortality worldwide due to the lack of accurate diagnosis of the pathogens causing infections. Currently, microbiological and molecular techniques are used to identify pathogenic bacteria. However, these techniques have limitations as they are time-consuming, cost-inefficient, and require trained personnel. Therefore, timely and precise identification of pathogenic bacteria is crucial for public safety. Our lab previously synthesized a fluorescent sensor array (3-hydroxyflavone derivatives) encapsulated in hyaluronic acid-based nanoparticles to identify bacterial species and recognize their Gram status. Though promising, this technique was relatively time-consuming and required high sample and volumes.

To overcome these limitations, …

Towards A Mode Of Action For The Anti-Schistosomal Aryl Hydantoins, Thomas Schulze

Theses & Dissertations

Schistosomiasis is a significant human disease caused by the helminth parasite Schistosoma mansoni. Praziquantel remains the only clinically used treatment, yet it is rapidly metabolized and only effective against the adult stage worm infection. Ro 13-3978 (AR02) is a potent antischistosomal compound with activity against multiple S. mansoni life stages; however, it manifests anti-androgenic activity. Additionally, the mechanism of action for worm clearance remains unknown. The structure of Ro 13-3979 was used to generate optimized derivatives, including AR102, that show increased potency towards worms, reduced off-target anti-androgen effects, and extended half-life thereby increasing the feasibility for a single-dose curative treatment. …

Combining The Tyrosine Kinase Inhibitor Cabozantinib And The Mtorc1/2 Inhibitor Sapanisertib Blocks Erk Pathway Activity And Suppresses Tumor Growth In Renal Cell Carcinoma, Yige Wu, Siqi Chen, Xiaolu Yang, Kazuhito Sato, Preet Lal, Andrew T Shinkle, Michael C Wendl, Tina M Primeau, Yanyan Zhao, Alanna Gould, Hua Sun, Jacqueline L Mudd, Jeremy Hoog, R Jay Mashl, Matthew A Wyczalkowski, Chia-Kuei Mo, Ruiyang Liu, John M Herndon, Sherri R Davies, Di Liu, Xi Ding, Ramaswamy Govindan, Shunqiang Li, James Hsieh, Ryan C Fields, Kian-Huat Lim, Cynthia X Ma, Li Ding, Feng Chen, Et Al.

2020-Current year OA Pubs

UNLABELLED: Current treatment approaches for renal cell carcinoma (RCC) face challenges in achieving durable tumor responses due to tumor heterogeneity and drug resistance. Combination therapies that leverage tumor molecular profiles could offer an avenue for enhancing treatment efficacy and addressing the limitations of current therapies. To identify effective strategies for treating RCC, we selected ten drugs guided by tumor biology to test in six RCC patient-derived xenograft (PDX) models. The multitargeted tyrosine kinase inhibitor (TKI) cabozantinib and mTORC1/2 inhibitor sapanisertib emerged as the most effective drugs, particularly when combined. The combination demonstrated favorable tolerability and inhibited tumor growth or induced …

Thermodynamics Of Ice Arena Geometry, Low- Emissivity Of Building Materials, And Natural Ventilation: An Energy Efficiency Study Of An Ice Arena In Rochester, Ny, Jonathan Sutton

Theses

This thesis explores the thermodynamic relationship between an ice arena’s ice sheet and building form. This exploration was conducted through an experiment focusing on the effects of architectural geometry, building material, and natural ventilation on ice heat gain. Ice arenas are giant refrigeration systems meant to sustain a sheet of ice in any climate, which is energy-intensive. There are many mechanical solutions to improving energy efficiency within ice arenas, leaving a gap for architectural solutions. Thermodynamics is how heat transfers or moves between space or objects. Heat or temperature wants to reach equilibrium, which means cold surfaces, objects, or air …

Simulation-Based Adaptive Interface For Personalized Learning Of Ai Fundamentals In Secondary School, Sara Guerreiro-Santalla, Dalila Duraes, Helen Crompton, Paulo Novais, Francisco Bellas

STEMPS Faculty Publications

This paper presents the first results on the validation of a new Adaptive E-learning System, focused on providing personalized learning to secondary school students in the field of education about AI by means of an adaptive interface based on a 3D robotic simulator. The prototype tool presented here has been tested at schools in USA, Spain, and Portugal, obtaining very valuable insights regarding the high engagement level of students in programming tasks when dealing with the simulated interface. In addition, it has been shown the system reliability in terms of adjusting the students’ learning paths according to their skills and …

Solar-Powered Microgrids In Northern California: An Opportunity For Resilience, Marina Riddle

Master's Projects and Capstones

Planned and unplanned power outages have been increasing in frequency and duration, negatively impacting all public sectors, and threatening public safety. These outages are deadly to those who rely on medical devices. As climate change-fueled extreme weather events (wildfires, earthquakes, storms, etc.) also increase in frequency, our electrical grid must be prepared to bounce back. Microgrids provide necessary redundancy and reliability. Through a novel GIS suitability analysis, based on solar radiation, land use type, local energy demand, distance to transmission lines, distance to roads, and slope, optimal locations for solar-powered microgrids throughout Northern California were determined. The counties of Fresno, …

Does Probiotic Supplementation Help Decrease Symptoms In Adults Previously Diagnosed With Major Depressive Disorder?, Alexa Hammock, Hayley Loiselle

Physician Assistant Capstones, 2020-current

Objective: To assess the effect of probiotic supplementation on clinical symptoms of major depressive disorder in adults. Design: Systematic literature review. Methods: Searches were performed on PubMed using the terms “adults with depression and probiotics”. The limits on PubMed were set to include randomized control trials, studies on adults, studies done within the last 10 years, studies done on patients that did not have depression, studies that did not use the Beck Depression Inventory, and studies that focused on other conditions. Results: Three studies were found that met search criteria: Reninghaus et al., Schaub et al., and Chahwan et al. …

Organic Dining Behaviour In British Restaurants, Lokman Dinc, Rong Huang

Plymouth Business School

The organic food market has experienced significant growth in recent decades all over the world. Within the context of the UK, a remarkable rise can be seen considering the recent popularisation of organic food products. With these trends in mind, the aim of this research is to develop better understanding of organic dining behaviour in British restaurants. To achieve this aim, this research used questionnaire technique and analyse the data using SEM.The key findings of the research confirmed that a range of factors, including advertisements through social media, knowledge, price, taste, quality, availability, and labelling, all significantly influence consumer intention …

Enhancing Wettability Prediction In The Presence Of Organics For Hydrogen Geo-Storage Through Data-Driven Machine Learning Modeling Of Rock/H2/Brine Systems, Zeeshan Tariq, Muhammad Ali, Nurudeen Yekeen, Auby Baban, Bicheng Yan, Shuyu Sun, Hussein Hoteit

Research outputs 2022 to 2026

The success of geological H2 storage relies significantly on rock–H2–brine interactions and wettability. Experimentally assessing the H2 wettability of storage/caprocks as a function of thermos-physical conditions is arduous because of high H2 reactivity and embrittlement damages. Data-driven machine learning (ML) modeling predictions of rock–H2–brine wettability are less strenuous and more precise. They can be conducted at geo-storage conditions that are impossible or hazardous to attain in the laboratory. Thus, ML models were utilized in this research to accurately model the wettability behavior of a ternary system consisting of H2, rock minerals (quartz and mica), and brine at different operating geological …

Leaf Thermal Regulation Strategies Of Canopy Species Across Four Vegetation Types Along A Temperature And Precipitation Gradient, Yingying Zhou, Nawatbhrist Kitudom, Sophie Fauset, Martijn Slot, Zexin Fan, Jianping Wang, Weiwei Liu, Hua Lin

School of Geography, Earth and Environmental Sciences

The ecophysiological processes of leaves are more related to leaf temperature (Tl) than air temperature (Ta). Transpiration and leaf physical traits enable plants to maintain Tl within a thermal range. However, it is challenging to quantitatively study leaf thermal regulation strategies, due to the complex interaction between thermal effects of transpiration and leaf physical traits. We utilized a 3-T method that compares Tl, Ta, and Tn (the temperature of non-transpiring leaves) investigate thermal regulation strategies of dominant canopy species in four vegetation types, including a savanna woodland, a tropical rain forest, a subtropical evergreen broad-leaved forest, and a temperate mixed …

Tipping The Mesoscales: Advances In Multipeak Bragg Coherent Diffraction Imaging, J. Nicholas Porter

Theses and Dissertations

Material failure begins with strain between atoms and cascades upward into macroscopic damage such as cracks. Therefore, our ability to predict (and therefore prevent) material failure is largely limited by our understanding of this process. This understanding, however, has been impeded by the difficulty of directly observing such phenomena. In this thesis, I discuss recent advances in Bragg coherent diffraction imaging (BCDI) which produce three-dimensional, mesoscopic images of interior strain in microcrystals. In particular, I present a novel algorithm, based on the concept of cyclic-constrained optimization (CCO), for the rapid, coupled reconstruction of a microcrystal from multiple Bragg diffraction patterns. …

Fabrication And Characterization Of Flexible Microelectrode Arrays On Kapton Polyimide For Implantable Spinal Cord Stimulation Applications, Nabil Jamhour

Theses and Dissertations

Recent advances in spinal cord stimulation (SCS) technology have made a significant impact in the treatment of chronic pain which is a prevalent issue amongst 20% of the population in developed nations. A few medical device manufactures have developed SCS devices that have been studied in clinical environments and reported to be effective and safe for commercial use. However, the current SCS devices available are bulky, rigid, and still present infection, fibrosis, discomfort, pulse delivery challenges and other concerns for patients. In this study, flexible electrodes processed on Kapton® polyimide films by physical vapor and inkjet deposition are fabricated and …

Students’ Perception Of Possibilities Of Using Business Process Modeling To Improve Organizations, Małgorzata Oleś-Filiks

Studia i Materiały Wydział Zarządzania Uniwersytet Warszawski

Purpose: The main aim of this article is to analyze the knowledge of the students – future users of these systems – of the awareness of the use and possibilities of using business process modeling in improving the organization. Design/Methodology/Approach: The research was carried out using the CAWI method. The questionnaire prepared for this purpose was first verified with the participation of experts in the field of business process modeling and then made available to students to fill in on the servers of the Faculty of Management of the University of Warsaw. The study concerned general knowledge of concepts related …

Optimizing Sepsis Management Through Enhanced Protocol Compliance In The Emergency Department, Oscar J. Castillo

Master's Projects and Capstones

Problem: The Quality Improvement (QI) Project focused on improving early sepsis management and sepsis bundle adherence among Emergency Department (ED) nurses to decrease sepsis mortality rates and avoidable length of hospital stays (LOS).

Context: A group of Clinical Nurse Leaders (CNL) students evaluated sepsis protocol compliance at Hospital A's ED, which provides critical care for patients with various medical conditions. The CNL students concentrated on patients identified with sepsis for the QI Project.

Interventions: Limitations and time did not allow for the implementation of interventions. Recommendations offered to management included increasing sepsis training biannually and intravenous placement skills, offering sepsis …

Limiting Privilege: Upward Mobility Within Higher Education In Socialist Poland, Agata Zysiak

Central European Studies

State socialism tried to industrialize, urbanize, encourage the more frequent washing of hands, urge people to leave the church, emancipate women, and electrify cities—all within a single lifetime. Central to these initiatives was extending educational opportunities to the working class and creating a vision of an egalitarian socialist university that offered advancement for all. Limiting Privilege: Upward Mobility Within Higher Education in Socialist Poland traces the possibilities and limits of this goal by looking at a model socialist university established in 1945 in the working-class city of Łódź, Poland. Initially a flagship project of socialist modernization, the university tried to …

Personal Leadership Development Plan, Tristan Parker

Mechanical Engineering and Materials Science Independent Study

If there is one thing I have learned this semester from this course, it's that typing someone’s personality based on a limited amount of characteristics or somewhat abstract qualities is tough! This is true even when typing oneself, as I feel like my feelings or attitudes towards the world are constantly changing. Considering this, I tend to place more merit in long-term habits or qualities that shape who a person is. Based on my personal experience, I would type myself on the Myers-Briggs Chart as an ISTP, or the Virtuoso.