Digital Commons Network^™

Impacts Of Land Use And Groundwater Inputs On Biological Stream Health And Habitat Of Jennings Creek, Bowling Green, Kentucky, Allison Francis, Jason S. Polk

Kentucky Water Resources Annual Symposium

No abstract provided.

The Role Of Beavers In Mediating Short-Term Organic Matter Accretion In Kentucky Acep Wre Easements, Jessica B. Moon, Marissa Miles, Logan Firkins, Karen A. Baumann, Michael B. Flynn

Kentucky Water Resources Annual Symposium

No abstract provided.

Characterizing Louisville Wetlands From Above And Below To Better Predict Wetland Carbon Sink-Source Status, Andrea E. Gaughan, Andrew S. Mehring, Mark Tierney, David Brown, Kassidy Haynes, Madison Cicha

Kentucky Water Resources Annual Symposium

No abstract provided.

A Universal Method For Generating Knockout Mice In Multiple Genetic Backgrounds Using Zygote Electroporation., Tomohiro Tamari, Yoshihisa Ikeda, Kento Morimoto, Keiko Kobayashi, Saori Mizuno-Iijima, Shinya Ayabe, Akihiro Kuno, Seiya Mizuno, Atsushi Yoshiki

Faculty Research 2023

Genetically engineered mouse models are essential tools for understanding mammalian gene functions and disease pathogenesis. Genome editing allows the generation of these models in multiple inbred strains of mice without backcrossing. Zygote electroporation dramatically removed the barrier for introducing the CRISPR-Cas9 complex in terms of cost and labour. Here, we demonstrate that the generalised zygote electroporation method is also effective for generating knockout mice in multiple inbred strains. By combining in vitro fertilisation and electroporation, we obtained founders for knockout alleles in eight common inbred strains. Long-read sequencing analysis detected not only intended mutant alleles but also differences in read …

What Are The Causes And Remedies Of Wrongful Convictions?, Audree Alick

The Mid-Southern Journal of Criminal Justice

Wrongful convictions, also known as miscarriages of justice, are very common in the criminal justice system today. With the first known wrongful conviction in 1872, to the most recent in 2023, researchers have similarly identified three causes of wrongful convictions: false confessions, eyewitness errors, and investigative misconduct. Wrongful convictions can cause many physical and mental effects on post-exonerees and currently incarcerated individuals, including but not limited to, clinical anxiety, depression, and PTSD. Analyses of DNA (deoxyribonucleic acid) have proven instrumental in cases of wrongful convictions. Each exoneree should have access to the DNA database to test against the DNA evidence …

Moving In The Shadows: The Reasons Why Men Purchase Commercial Sexual Services And The Connection To Strain Theory, Kelley Barry

The Mid-Southern Journal of Criminal Justice

Prostitution has been a feature of human civilization since its establishment. Yet, existing research typically encompasses the perspective of the seller, leaving the context of an entire faction somewhat undiscovered. In working to better understand this population, this paper emphasizes the perspective of male buyers and their reasons for purchasing sexual services. To further examine the role that men assume in this type of exchange, their input is compared against the central tenets of Agnew’s (1992) strain theory.

The Student Movement Volume 108 Issue 1: '23 And Me: Welcome To The Au Family!, Anneliese Tessalee, Savannah Tyler, Colin Cha, Amelia Stefanescu, Nailea Soto, Daena Holbrook, Madison Vath, Melissa Moore, Brendan Oh, Nathaniel Miller, Sumin Lee, Corinna Bevier, Bella Hamann, Reagan Westerman, Lexie Dunham, Alyssa Caruthers, Anna Rybachek, Rodney Bell Ii, Chris Ngugi

The Student Movement v. 108 (2023-2024)

HUMANS

Babbling at the Crayon Box, Anneliese Tessalee

Dorm Sweet Dorm, Savannah Tyler

Surviving Freshman Year 101, Colin Cha

ARTS & ENTERTAINMENT

AU's Reception of "Barbie", Amelia Stefanescu

"Hey, How Was Your Summer?", Nailea Soto

Sewing as an Art Form: My Experience as a First-Time Formal Dressmaker, Daena Holbrook

Shadow & Bone: Reentering the Grishaverse, Madison Vath

NEWS

Another Generation, Another Convocation, Melissa Moore

Canada's Fiery Struggle: The Ongoing Battle Against Wildfires, Brendan Oh

Labor Day, the Writers' Strikes, and Fairness, Nathaniel Miller

IDEAS

Antibiotic Resistance, Sumin Lee

Chapel Credits: Fair or Unfair?, Corinna Bevier

From Flowers to Fires: Does …

Baseline Immune States (Bis) Associated With Vaccine Responsiveness And Factors That Shape The Bis., Djamel Nehar-Belaid, Mark Sokolowski, Sathyabaarathi Ravichandran, Jacques Banchereau, Damien Chaussabel, Duygu Ucar

Faculty Research 2023

Vaccines are among the greatest inventions in medicine, leading to the elimination or control of numerous diseases, including smallpox, polio, measles, rubella, and, most recently, COVID-19. Yet, the effectiveness of vaccines varies among individuals. In fact, while some recipients mount a robust response to vaccination that protects them from the disease, others fail to respond. Multiple clinical and epidemiological factors contribute to this heterogeneity in responsiveness. Systems immunology studies fueled by advances in single-cell biology have been instrumental in uncovering pre-vaccination immune cell types and genomic features (i.e., the baseline immune state, BIS) that have been associated with vaccine responsiveness. …

A Phase I Clinical Trial Of Oncolytic Adenovirus Mediated Suicide And Interleukin-12 Gene Therapy In Patients With Recurrent Localized Prostate Adenocarcinoma, Shyam Nyati, Hans Stricker, Kenneth N. Barton, Pin Li, Mohamed A. Elshaikh, Haythem Y. Ali, Stephen L. Brown, Clara Hwang, James O. Peabody, Svend O. Freytag, Benjamin Movsas, Farzan Siddiqui

Radiation Oncology Articles

In a phase I dose escalation and safety study (NCT02555397), a replication-competent oncolytic adenovirus expressing yCD, TK and hIL-12 (Ad5-yCD/mutTKSR39rep-hIL-12) was administered in 15 subjects with localized recurrent prostate cancer (T1c-T2) at increasing doses (1 × 1010, to 1 × 1012 viral particles) followed by 7-day treatment of 5-fluorocytosine (5-FC) and valganciclovir (vGCV). The primary endpoint was toxicity through day 30 while the secondary and exploratory endpoints were quantitation of IL-12, IFNγ, CXCL10 and peripheral blood mononuclear cells (PBMC). The study maximum tolerated dose (MTD) was not reached indicating 1012 viral particles was safe. Total 115 adverse events were observed, …

Elevated Risk Of Compound Extreme Precipitation Preceded By Extreme Heat Events In The Upper Midwestern United States, Manas Khan, Rabin Bhattarai, Liang Chen

Department of Earth and Atmospheric Sciences: Faculty Publications

Compound extreme events can potentially cause deadlier socio-economic consequences. Although several studies focused on individual extreme climate events, the occurrence of compound extreme events is still not well studied in the upper Midwestern United States. In this study, compound extreme precipitation preceded by extreme hot day events was investigated. Results showed a strong linkage between extreme precipitation events and extreme hot days. A significant increasing trend was noticed mainly in Iowa (10.1%), northern parts of Illinois (5.04%), and Michigan (5.04%). Results also showed a higher intensity of extreme precipitation events preceded by an extremely hot day compared to the intensity …

Completions 2022-23, Southwestern Oklahoma State University

IPEDS

IPEDS Report created by the SWOSU Office of Institutional Research

Fall Enrollment 2022-23, Southwestern Oklahoma State University

IPEDS

IPEDS Report created by the SWOSU Office of Institutional Research

State, National Leaders Share Insights On Leading Through Disaster, Clara Turnage

University of Mississippi News

OXFORD, Miss. – Five state and national leaders shared lessons from their struggles and successes of leadership in crisis Thursday evening (Sept. 14) at the University of Mississippi's Gertrude C. Ford Center for the Performing Arts.

Observations On A 40-Year January Bird Census In Boone County, Nebraska, 1978–2017, Wayne Mollhoff

Zea E-Books Collection

For 40 years Wayne Mollhoff conducted a personal bird census every January. He explains: "After having run several Breeding Bird Survey routes, and participated in several Christmas Bird Counts, I became curious to see what might be found on a winter count under the more tightly controlled parameters of a census, as contrasted with Christmas counts done with variable numbers of observers."

The count was set up similarly to the USGS Breeding Bird Survey routes with 50 stops, one-half mile (800 meters) apart, all birds counted for 3 minutes, with birds counted at one stop not counted again at following …

Impacts Of Land Use And Groundwater Inputs On Biological Stream Health And Habitat Of Jennings Creek, Bowling Green, Kentucky, Allison Francis, Jason S. Polk

Kentucky Water Resources Annual Symposium

No abstract provided.

Temperature-Responsive Membrane With Nano-Sized Catalysts For The Treatment Of Contaminated Groundwater, Rollie Mills, Dibakar Bhattacharyya

Kentucky Water Resources Annual Symposium

No abstract provided.

Full Program Proceedings For 2023 Kentucky Water Resources Symposium, Kentucky Water Research Institute

Kentucky Water Resources Annual Symposium

No abstract provided.

Befriending Your Vagus Nerve: A Storybook For Children, Miira Jannika Sarimo

Mindfulness Studies Theses

The vagus nerve, which is the longest of the cranial nerves, extends from the brain to the majority of organs in the body and has, therefore, been dubbed the Wanderer. It carries both sensory (afferent) information about the organs to the brain and motor information (efferent) from the brain to the organs. Stimulating the vagus nerve has been the interest of researchers since the late 1800s when delivering electricity to the nerve was used to treat acute epileptic seizures. Today, vagus nerve stimulation has been approved as treatment for morbid obesity and treatment-resistant depression as well. More natural techniques to …

September 15, 2023 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Map3k19 Regulatory Variation In Populations With African Ancestry May Increase Covid-19 Severity, Zhongshan Cheng, Yi Cai, Ke Zhang, Jingxuan Zhang, Hongsheng Gui, Yu-Si Luo, Jie Zhou, Brian Deveale

Behavioral Health Articles

To identify ancestry-linked genetic risk variants associated with COVID-19 hospitalization, we performed an integrative analysis of two genome-wide association studies and resolved four single nucleotide polymorphisms more frequent in COVID-19-hospitalized patients with non-European ancestry. Among them, the COVID-19 risk SNP rs16831827 shows the largest difference in minor allele frequency (MAF) between populations with African and European ancestry and also shows higher MAF in hospitalized COVID-19 patients among cohorts of mixed ancestry (odds ratio [OR] = 1.20, 95% CI: 1.10-1.30) and entirely African ancestry (OR = 1.30, 95% CI: 1.02-1.67). rs16831827 is an expression quantitative trait locus of MAP3K19. MAP3K19 expression …

Numerical Simulation Of A Lab-On-Chip For Dielectrophoretic Separation Of Circulating Tumor Cells, Abdallah M. Alkhaiyat, Mohamed Badran

Faculty Journal Articles

No abstract provided.

2023-09-15 Minutes & Appendices, Longwood University

Board of Visitors Meeting Minutes 1964-

No abstract provided.

2023 September 15 - Board Of Trustees Agenda And Minutes, Board Of Trustees, East Tennessee State University

Board of Trustees Agendas and Minutes

No abstract provided.

2023 September 15 - Board Of Trustees Academic, Research, And Student Success Committee Agenda And Minutes, Board Of Trustees, East Tennessee State University

Board of Trustees Agendas and Minutes

No abstract provided.

Diversity And Distribution Of Ascidians, Lauren M. Stefaniak

Marine Science

My research focuses on the biodiversity and biogeography of ascidians, the mechanisms controlling the distribution of species and communities, and how human activities, such as shipping, coastal hardening, and climate changes can alter those distributions. Working with my masters and undergraduate student researchers, I use morphological and molecular taxonomy, molecular ecology, and observational and manipulative field and lab studies to explore these questions...

This article was published Open Access through the CCU Libraries Transformative Agreement Program. The article was first published in genesis, the Journal of Genetics and Development: https://doi.org/10.1002/dvg.23548

Pilot Study: An Exploration Of Medication Assisted-Treatment (Mat) For Indigenous Americans Within Tribal Healing To Wellness Courts, Fanni Farago, Lindsay Smith, Violette Cloud, Michael Gordon, Faye Taxman

Qualitative Criminology (QC)

Considering the opioid epidemic’s adverse and disproportionate consequences on Indigenous American communities across the nation, United States federal agencies (i.e., Indian Health Service, the Bureau of Indian Affairs, and the White House Office of National Drug Control Policy) and Tribal nations are urgently calling for more substance use treatment and prevention efforts. Problem-solving courts (PSCs) are a well-known innovation for treating individuals with substance use disorders (SUDs) and those who have committed non-violent offenses. However, very little is known about these courts in indigenous communities and how they address substance use disorders. Drawing on a small sample of court coordinators …

The Diamond, September 15, 2023, Dordt University

Dordt Diamond

• Front Page: Dordt Turns Students Away Due to Record Enrollment; A Green Partnership; Men's Basketball Goes to Ecuador
• News: Agriculture Field Day Presents on Current Issues of Today; Christian Non-Profit to Host First Young Author's Conference in Sioux Center; Dordt Increases Parking Spaces to Meet Increased Demand; What Happens on Campus Over the Summer?; New Faces in Residence Life; Faculty Prepares for Higher Retention; New Year, New Website
• Feature: A Dive into The Squares; Dordt Gains Society for Women Engineers; The Dordt Republicans Club Plans to Host Political Candidates; Spreading AMOR in Nicaragua; How's Howard?; Sara de …

Protocol For Expression Of Murine Milk Using Modified Human Breast Pump Parts, Cydney Meyer, Joseph L Alcorn

Faculty, Staff and Student Publications

Understanding the nutritional and immunomodulatory components of breast milk is crucial to developing novel mechanisms to optimize neonatal health. Here, we present a protocol to express and isolate murine milk in sufficient quantities for further analysis of components and bioactivity. We describe steps for separating dams from pups, administering intraperitoneal anesthetic and oxytocin, and expressing milk using a minimally modified and readily available commercial breast pump parts. For complete details on the use and execution of this protocol, please refer to Meyer et al. (2022).

Immune-Active Tumor-Adjacent Tissues Are Associated With Favorable Prognosis In Stage I Lung Squamous Cell Carcinoma, Lisha Ying, Chunliu Zhang, Alexandre Reuben, Yiping Tian, Jiaoyue Jin, Canming Wang, Jing Bai, Xinyuan Liu, Jianfei Fang, Tingting Feng, Chenyang Xu, Rui Zhu, Minran Huang, Yingqi Lyu, Tingting Lu, Xiaodan Pan, Jianjun Zhang, Dan Su

Faculty, Staff and Student Publications

The immunogenomic features of tumor-adjacent lungs (TALs) in stage I lung squamous cell carcinoma (LUSC) are not clear. Multiomics analyses of tumor tissues and paired TALs from 59 stage I LUSC patients were performed. Compared to tumors, TALs exhibited a better-preserved immune contexture indicated by upregulation of immune pathways, increased immune infiltration, and higher expression of immune effector molecules. Notably, TALs had no mutations in PTEN and KEAP1, a lower incidence of human leukocyte antigen (HLA) loss and higher expression of HLA class I genes, major histocompatibility complex (MHC) I chaperones, and interferon (IFN)-γ-associated genes. Digital spatial profiling validated the …

Sugar-Sweetened Beverages And Artificially Sweetened Beverages Consumption And The Risk Of Nonalcoholic Fatty Liver (Nafld) And Nonalcoholic Steatohepatitis (Nash), Tung Sung Tseng, Wei Ting Lin, Peng Sheng Ting, Chiung Kuei Huang, Po Hung Chen, Gabrielle V. Gonzalez, Hui Yi Lin

School of Public Health Faculty Publications

Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are fast becoming the most common chronic liver disease and are often preventable with healthy dietary habits and weight management. Sugar-sweetened beverage (SSB) consumption is associated with obesity and NAFLD. However, the impact of different types of SSBs, including artificially sweetened beverages (ASBs), is not clear after controlling for total sugar intake and total caloric intake. The aim of this study was to examine the association between the consumption of different SSBs and the risk of NAFLD and NASH in US adults. The representativeness of 3739 US adults aged ≥20 years …