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Usa Archaeology Museum Newsletter - September 2023, Archaeology Museum

Archaeology Museum Newsletters

In this edition of the Archaeology Museum's newsletter:

• Unwritten: Archaeology & Oral History of Jim Crow Mobile Exhibit
• Unwritten: Archaeology & Oral History of Jim Crow Mobile Exhibit Speaker Series Schedule
• Choctaw Nation Visits the Museum
• Alabama Archaeological Society Southwest Chapter Fall Speaker Series
• Alabama Archaeology Day
• Halloween at the Museum
• Native Plants Garden Update
• Giving to the Archaeology Museum

Sex Differences In Neurological Emergencies Presenting To Multiple Urban Level 1 Trauma Centers, Linda Papa, John J. Cienki, Jason W. Wilson, Virginia Axline, Emily A. Coyle, Ryan C. Earwood, Josef G. Thundiyil, Jay G. Ladde

Emergency Medicine Articles

Previous studies have suggested that there are sex differences in the treatment and outcome of neurological emergencies; however, research identifying the role these sex differences play in the management of neurological emergencies is lacking. More knowledge of the way sex factors into the pathophysiology of neurological emergencies will be helpful in improving outcomes for these patients. The aim of this cross-sectional study was to assess the prevalence and management of neurological emergencies while evaluating sex differences in the diagnosis and treatment of these emergencies. We analyzed a cohort of 530 adult patients from four level 1 trauma centers over a …

Rising Coastal Groundwater As A Result Of Sea-Level Rise Will Influence Contaminated Coastal Sites And Underground Infrastructure, K. Hill, D. Hirschfeld, C. Lindquist, F. Cook, S. Warner

Landscape Architecture and Environmental Planning Faculty Publications

Sea-level rise (SLR) will cause coastal groundwater to rise in many coastal urban environments. Inundation of contaminated soils by groundwater rise (GWR) will alter the physical, biological, and geochemical conditions that influence the fate and transport of existing contaminants. These transformed products can be more toxic and/or more mobile under future conditions driven by SLR and GWR. We reviewed the vulnerability of contaminated sites to GWR in a US national database and in a case comparison with the San Francisco Bay region to estimate the risk of rising groundwater to human and ecosystem health. The results show that 326 sites …

Volume 1, Issue 4, Bryant University

Bryant Bulldog Bulletin (2023-2024)

No abstract provided.

Time-Resolved Cryo-Em (Tr-Em) Analysis Of Substrate Polyubiquitination By The Ring E3 Anaphase-Promoting Complex/Cyclosome (Apc/C), Tatyana Bodrug, Kaeli A. Welsh, Derek L. Bolhuis, Ethan Paulаkonis, Raquel C. Martinez-Chacin, Bei Liu, Nicholas Pinkin, Thomas Bonacci, Liying Cui, Pengning Xu, Olivia Roscow, Sascha Josef Amann, Irina Grishkovskaya, Michael J. Emanuele, Joseph S. Harrison, Joshua P. Steimel, Klaus M. Hahn, Wei Zhang, Ellen D. Zhong, David Haselbach, Nicholas G. Brown

Pacific Faculty Work

Substrate polyubiquitination drives a myriad of cellular processes, including the cell cycle, apoptosis and immune responses. Polyubiquitination is highly dynamic, and obtaining mechanistic insight has thus far required artificially trapped structures to stabilize specific steps along the enzymatic process. So far, how any ubiquitin ligase builds a proteasomal degradation signal, which is canonically regarded as four or more ubiquitins, remains unclear. Here we present time-resolved cryogenic electron microscopy studies of the 1.2 MDa E3 ubiquitin ligase, known as the anaphase-promoting complex/cyclosome (APC/C), and its E2 co-enzymes (UBE2C/UBCH10 and UBE2S) during substrate polyubiquitination. Using cryoDRGN (Deep Reconstructing Generative Networks), a neural …

The Localization Of Centromere Protein A Is Conserved Among Tissues, Eleonora Cappelletti, Francesca M. Piras, Lorenzo Sola, Marco Santagostino, Jessica L. Petersen, Rebecca R. Bellone, Carrie J. Finno, Sichong Peng, Ted S. Kalbfleisch, Ernest Bailey, Solomon G. Nergadze, Elena Giulotto

Department of Animal Science: Faculty Publications

Centromeres are epigenetically specified by the histone H3 variant CENP-A. Although mammalian centromeres are typically associated with satellite DNA, we previously demonstrated that the centromere of horse chromosome 11 (ECA11) is completely devoid of satellite DNA. We also showed that the localization of its CENP-A binding domain is not fixed but slides within an about 500 kb region in different individuals, giving rise to positional alleles. These epialleles are inherited as Mendelian traits but their position can move in one generation. It is still unknown whether centromere sliding occurs during meiosis or during development. Here, we first improve the sequence …

Ms 106 Guide To Ferid Murad, Md, Phd Papers (1959-1996), Ferid Murad (1936-2023)

Manuscript Finding Aids

The Ferid Murad, MD papers consists of fifiteen handwritten notebooks documenting Dr. Ferid Murad's research. The notebooks include research data presented in tables and charts, as well as Dr. Murad's notes. The notebooks span the years 1959-1970. In addition, the collection includes a small number of printed materials from organizations of which Dr. Murad was a part. Notably, there are manuals from his internship and residency at Massachusetts General Hospital, dating around 1965. See more at MS 106.

Usf School Of Architecture And Community Design, Hillsborough County Sustainability Action Plan, 2023, Brian Cook, Ping Wang, Maggie Winter

School of Architecture and Community Design

The Palmetto Beach Living Shoreline and Community Engagement Study addresses the ecological decline of McKay Bay and the vulnerability of the adjacent Palmetto Beach neighborhood to climate-related impacts. Through community-informed planning and scientific assessment, the project proposes habitat restoration and resilience strategies, serving as a reference for coastal adaptation and environmental remediation efforts in low-lying urban areas

Anharmonic Ir Absorption Spectra Of The Prototypical Interstellar Pahs Phenanthrene, Pyrene, And Pentacene In Their Neutral And Cation States, Vincent J. Esposito, Louis J. Allamandola, Christiaan Boersma, Jesse D. Bregman, Ryan C. Fortenberry, Alexandros Maragkoudakis, Pasquale Temi

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Combination band and overtone transitions of polycyclic aromatic hydrocarbon (PAH) cations in the 2000–2900 cm^-1 (5-3.5 µm) region are implicated as carriers of the ‘quasi-continuum’ observed in the near-infrared (IR) emission spectra of many astronomical objects. In neutral PAHs, the strongest absorption features are concentrated in the 700–900 cm^-1 (14–11 µm) range, which are associated with CH out-of-plane bending motions. Upon ionization, this shifts to the 1000–1600 cm^-1 (10–6 µm) range, where bands are associated with C=C stretches and CH in-plane bends. Anharmonicity is required to accurately characterize the IR absorption spectrum of PAHs, indicated herein by …

A Uplc-Ms/Ms Based Rapid, Sensitive, And Non-Enzymatic Methodology For Quantitation Of Dietary Isoflavones In Biological Fluids, Faraz Rashid, Sudeep Ghimire, Ashutosh K. Mangalam, Shailendra Giri

Neurology Articles

Dietary isoflavones, a type of phytoestrogens, have gained importance owing to their health-promoting benefits. However, the beneficial effects of isoflavones are mediated by smaller metabolites produced with the help of gut bacteria that are known to metabolize these phytoestrogenic compounds into Daidzein and Genistein and biologically active molecules such as S-Equol. Identifying and measuring these phytoestrogens and their metabolites is an important step towards understanding the significance of diet and gut microbiota in human health and diseases. We have overcome the reported difficulties in quantitation of these isoflavones and developed a simplified, sensitive, non-enzymatic, and sulfatases-free extraction methodology. We have …

Mechanistic Investigations Of A Novel Braf Regulatory Switch And Braftide, An Allosteric Peptide Inhibitor Of Braf, Alison Yu

Theses and Dissertations

RAF kinases (ARAF/BRAF/CRAF or Raf-1) are serine/threonine kinases in the MAPK (RAS-RAF-MEK-ERK) pathway. The MAPK pathway is crucial in development and normal cell function. These same roles are dysregulated in cancer; BRAF is the most frequently mutated isoform in cancers and in particular, activation loop mutants BRAF V600E/K mutants have the highest mutational incidence. Three FDA approved inhibitors potently inhibit BRAF V600E/K mutants. However, these same inhibitors fail to address the non-V600E/K mutations and result in paradoxical activation of the MAPK pathway. Two strategies were employed to address the limitations of the FDA-approved inhibitors: provide novel regulatory details of RAF …

The Current - Volume 34 Issue 2, Nova Southeastern University

Student Newspapers

No abstract provided.

Spin-Acoustic Control Of Silicon Vacancies In 4h Silicon Carbide, Jonathan R. Dietz, Boyang Jiang, Aaron M. Day, Sunil A. Bhave, Evelyn L. Hu

Purdue University Libraries Open Access Publishing Fund

Bulk acoustic resonators can be fabricated on the same substrate as other components and can operate at various frequencies with high quality factors. Mechanical dynamic metrology of these devices is challenging as the surface information available through laser Doppler vibrometry lacks information about the acoustic energy stored in the bulk of the resonator. Here we report the spin-acoustic control of naturally occurring negatively charged silicon monovacancies in a lateral overtone bulk acoustic resonator that is based on 4H silicon carbide. We show that acoustic driving can be used at room temperature to induce coherent population oscillations. Spin-acoustic resonance is shown …

The Real Cost: Targeted Advertising And Health Outcomes With Nicotine Vaping, Lance Daley

D.U.Quark

Vaping has become a highly popular form of using nicotine in the last decade and is thought to be a less harmful alternative to smoking combustible cigarettes. As popularity continues to increase, especially among teens and young adults, there is still very little information regarding the long-term health effects of vaping. This review will analyze vaping’s fast rise to prominence, negative physiological effects, as well as targeted flavoring and advertising towards youth. Although data is limited, nicotine vaping has been associated with many acute health problems, including increased blood pressure, increased arterial stiffness, and excess free radical production, all of …

High-Sensitivity Electronic Stark Spectrometer Featuring A Laser-Driven Light Source, J. S. Huff, K. M. Duncan, C. J. Van Galen, M. S. Barclay, W. B. Knowlton, B. Yurke, P. H. Davis, D. B. Turner, R. J. Stanley, R. D. Pensack

Materials Science and Engineering Faculty Publications and Presentations

We report developmental details of a high-sensitivity Stark absorption spectrometer featuring a laser-driven light source. The light source exhibits intensity fluctuations of ∼0.3% over timescales ranging from 1 min to 12 h, minimal drift (≤ 0.1%/h), and very little 1/f noise at frequencies greater than 200 Hz, which are comparable to or better than an arc-driven light source. Additional features of the spectrometer include balanced detection with multiplex sampling, which yielded lower noise in A, and constant wavelength or wavenumber (energy) spectral bandpass modes. We achieve noise amplitudes of ∼7 × 10⁻⁴ and ∼6 × 10^{−6 …}

Mark Brodl Stepping Down As Provost To Teach At Illinois Wesleyan, Julia Perez

News and Events (Discontinued Series)

No abstract provided.

With A Little Help At Home: The Impact Of Romantic Partner Support On Daily Burnout And Workplace Incivility, Matthew Aplin-Houtz

Dissertations

With rude and discourteous encounters in the workplace becoming more common, Workplace incivility (WI) is at an all-time high. As such, workers experience levels of burnout from these negative social interactions. The literature concedes that the results of these interactions lead to mounting burnout, causing negative physical and emotional outcomes at the individual and organizational levels. Considering that the literature also supports that employees have the potential to recover from burnout symptoms through rest, obtaining the perception of control of their circumstances, and cognitive reframing, the time and activities a worker spends at home carry the potential for minimizing burnout …

Response Patterns And Impact Of Mrd In Patients With Idh1/2-Mutated Aml Treated With Venetoclax And Hypomethylating Agents, Danielle Hammond, Sanam Loghavi, Sa A Wang, Marina Y Konopleva, Tapan M Kadia, Naval G Daver, Maro Ohanian, Ghayas C Issa, Yesid Alvarado, Nicholas J Short, Koji Sasaki, Naveen Pemmaraju, Guillermo Montalban-Bravo, Curtis A Lachowiez, Abhishek Maiti, Guillermo Garcia-Manero, Elias J Jabbour, Gautam Borthakur, Farhad Ravandi, Koichi Takahashi, Sherry R Pierce, Hagop M Kantarjian, Courtney D Dinardo

Faculty, Staff and Student Publications

No abstract provided.

September 21, 2023, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Researching The Future: Scenarios To Explore The Future Of Human Genome Editing, Cynthia Selin, Lauren Lambert, Stephanie Morain, John P Nelson, Dorit Barlevy, Mahmud Farooque, Haley Manley, Christopher T Scott

Center for Medical Ethics and Health Policy Staff Publications

Background: Forward-looking, democratically oriented governance is needed to ensure that human genome editing serves rather than undercuts public values. Scientific, policy, and ethics communities have recognized this necessity but have demonstrated limited understanding of how to fulfill it. The field of bioethics has long attempted to grapple with the unintended consequences of emerging technologies, but too often such foresight has lacked adequate scientific grounding, overemphasized regulation to the exclusion of examining underlying values, and failed to adequately engage the public.

Methods: This research investigates the application of scenario planning, a tool developed in the high-stakes, uncertainty-ridden world of corporate strategy, …

Asset-Based Approaches To Multilingual Students’ Computer Science Identity Development, Sharin Rawhiya Jacob, Mark Warschauer

Journal of Computer Science Integration

While computer science identity development has been examined in several studies, there is much to learn about the development of multilingual students’ computer science (CS) identities. To develop strong CS identities, multilingual students must engage in culturally and linguistically sustaining curriculum, pedagogy, and interaction that draws from their rich and varied resources. This theoretical paper is grounded in a justice-centered, asset-based framework that views the traditions and practices in students’ cultures and communities as strong contributors to knowledge construction in STEM. We draw on multiple studies exploring multilingual student CS identity development to better understand how their personal, familial, community-based, …

Examining The Role Of Urban Policy, Built Environment, And Physical Activity In Mexico City, Eugen Resendiz Bontrud

Brown School Graduate Student Theses and Dissertations

Over the past three decades, Latin America has undergone major demographic, lifestyle, and epidemiological transitions. These rapid transitions are relevant contributors to social and health inequities in the region. Physical inactivity is a known risk factor for several adverse health outcomes, including Type 2 diabetes, coronary heart disease, and site-specific cancers (breast, ovarian, endometrial, and colon). Latin America has the highest prevalence of physical inactivity among all global regions, with one in every three Latin Americans being physically inactive. Research exploring the link between urban policies, built environment characteristics, and physical activity has grown over the past two decades. Nevertheless, …

2023 State Of The University Address, Aondover Tarhule

State of the University Addresses

Annual address delivered by the president of Illinois State University discussing the university's accomplishments and plans for the future.

Development And Evaluation Of A Wearable Peripheral Vascular Compensation Sensor In A Swine Model Of Hemorrhage, Francesca Bonetta-Misteli, Toi Collins, Todd Pavek, Madison Carlgren, Derek Bashe, Antonina Frolova, Leonid Shmuylovich, Christine M O'Brien

2020-Current year OA Pubs

Postpartum hemorrhage (PPH) is the leading and most preventable cause of maternal mortality, particularly in low-resource settings. PPH is currently diagnosed through visual estimation of blood loss or monitoring of vital signs. Visual assessment routinely underestimates blood loss beyond the point of pharmaceutical intervention. Quantitative monitoring of hemorrhage-induced compensatory processes, such as the constriction of peripheral vessels, may provide an early alert for PPH. To this end, we developed a low-cost, wearable optical device that continuously monitors peripheral perfusion via laser speckle flow index (LSFI) to detect hemorrhage-induced peripheral vasoconstriction. The measured LSFI signal produced a linear response in phantom …

Boosting Glycolysis To Combat Fragile Bone In Type 1 Diabetes, Zixue Jin, Brendan Lee

Faculty, Staff and Students Publications

Individuals with type 1 diabetes (T1D) have an increased risk of osteoporosis and fracture. In this issue of Cell Chemical Biology, Ji et al.1 show that impaired glucose metabolism in the bone-forming osteoblast drives diabetic osteoporosis in Akita mice, a mouse model of T1D.

Preparing Counselors To Meet The Needs Of Transgender Clients, Kristy Carangi

Antioch University Dissertations & Theses

This exploratory quantitative study tests the effectiveness of a three-hour Transgender Training Intervention for increasing the gender identity competence of counselors and counselors-in-training. Participants (N = 4) were recruited online and completed the 20-item Counselor Competence Gender Identity Survey (CCGIS) before and after the virtual training intervention. Data were analyzed using descriptive statistics. Results indicated that mean total CCGIS scores increased from 127.0 in the pretest to 138.75 in the posttest, a 9.25% increase. The largest gains were made on the Gaining Knowledge/Skills to Counsel Gender Diverse Individuals subscale (CCGIS-KS). Mean scores on the CCGIS-KS increased from 24.25 in the …

Restructuring A Developmental Esl Course At An Urban Community College: Asking The Right Questions, Deniz Gokcora, Raymond Oenbring

Michigan Reading Journal

This article provides an example of the integration of topics of race and racial awareness and anti-racist pedagogy into an ESL developmental writing course in a community college setting. The study describes how the lead author has redesigned an ESL developmental writing course at the Borough of Manhattan Community College (BMCC) to include an explicit focus on critical racial pedagogy and social justice topics to foster students’ critical thinking and encourage students to be socially responsible individuals in a challenging global world. The manuscript offers insights into how an advanced ESL remedial writing course can be a suitable setting to …

Knit-Mycelium Hybrids: Designing And Scaling Up With Bio Fabrication Systems Based On Mycocrete Injection In 3d Knitted Tubular Formworks, Romy Kaiser, Jane Scott, Martyn Dade-Robertson, Elise Elsacker

Textile Intersections Conference Series

This paper investigates the design potential of monolithically grown Mycelium-based Composites (MBCs) focusing on the integration of 3D knitted formworks within the fabrication process. Mycelium has gained attention as a sustainable, biodegradable, construction material with insulating, and self-healing capabilities. While there have been advancements in MBC, challenges remain in terms of structural complexity, stability, and design control at scale. Recent interest has emerged in digital fabrication methods and mould creation using textile logics and CNC knitting but fabricating mycelium within tubular soft moulds presents a lack of stability and uneven growth distribution. This, however, can be overcome by a novel …

Towards Performative Woven Textile-Form Interfaces, Alice Buso, Holly Mcquillan, Milou Voorwinden, Elvin Karana

Textile Intersections Conference Series

In this paper, we explore how textile-form thinking, i.e., the simultaneous design and construction of the textile and form, can be leveraged as a strategy to embrace and unlock the performative potential of woven interactive textiles to building towards more intuitive interactions with woven interactive textiles in our everyday. First, we designed and wove five textile-form interfaces, working as contact switches and sensors, with sensing capabilities and diverse performative qualities. Then, we investigated the action possibilities of the interfaces in an exploratory study. Grounded on the study's outcomes, we identified three design themes relative to the performativity of our woven …

Textile Intersections 2023: Exhibition Catalogue, Hanna Landin, Riikka Townsend, Bruna Petreca

Textile Intersections Conference Series

Catalogue of Textile Intersections 2023 Exhibition - Collaborations in Textiles Design Research