Digital Commons Network^™

Anti-Cancer Activity Of Rhus Coriaria (Sumac) Against 5-Fluorouracil-Resistant Colorectal Cancer Cells, Zohra Nausheen Nizami

Thesis/ Dissertation Defenses

Colorectal cancer (CRC) is the second leading cause of cancer-related death, both worldwide and in UAE. 5-fluorouracil (5-FU), a pyrimidine analogue, is a chemotherapeutic agent that is an integral component of chemotherapy regimens for CRC treatment. However, 5-FU resistance (intrinsic and/or acquired) inhibits their clinical efficacy. In recent years, there has been a growing popularity for plantbased cancer therapeutics, specifically using phytochemical compounds. Rhus coriaria (Sumac) is a Mediterranean plant whose fruits are used as a spice and medicinal herb. Extracts of Rhus coriaria fruits have been reported to exhibit anticancer activity against breast and CRC cancers. In the present …

Population Structure And Genetic Diversity Of The Socotra Cormorant (Phalacrocorax Nigrogularis), Noura Mabkhout Almansoori

Thesis/ Dissertation Defenses

The Socotra cormorants (Phalacrocorax nigrogularis) are regional endemic seabirds restricted to the Arabian Gulf, Gulf of Oman, and the Arabian Sea. This species is classified as vulnerable by the IUCN Red List. However, no population genetic study has been conducted on P. nigrogularis in their range, and population structure, gene flow and connectivity between colonies is unknown. Likewise, genetic diversity of this species has not yet been characterized. Thus, the aim of this thesis was to fill these gaps by inferring population structure, assessing gene flow and genetic diversity of Socotra cormorant colonies in their known distribution range. For this …

Developing A Teaching Unit Based On Science, Technology, Society, And The Environment Approach, And Measuring Its Effect On Developing Ethical Decision - Making Skills Among Sakhnin College Students تطوير وحدة تدريسية قائمة على منحى العلم والتقانة والمجتمع والبيئة وقياس أثرها في تنمية مهارات اتخاذ القرار الأخلاقي لدى طالبات كلية سخنين, Manal Al-Khazen, Abdullah Mohammad Khataibeh, Abdel Ra’Ouf Mohammad Al-Dairi

Jordanian Educational Journal

Abstract:

The study aimed to uncover the effect of a teaching unit developed in accordance with science, technology, society and the environment approach in developing the ethical decision-making skills of Sakhnin College students. The quasi-experimental methodology was used, where the study sample consisted of (20) female students of a second year from Sakhnin College, who were randomly selected, as they underwent a pre-test on ethical decision-making, and then underwent the same test after they were taught two academic units according to science, technology, society and environment approach. The results of the study showed the existence of an impact of the …

The Level Of Enlightenment Of Arabic Language Teachers With The Writing Concept And Its Learning And Teaching Principles مستوى تنوّر معلمي اللغة العربيّة مفهوم الكتابة ومبادئ تعلّمها وتعليمها, Ali Saud Al-Rahamneh, Mohammad Fu'ad Al Hawamdeh

Jordanian Educational Journal

Abstract:

This study aimed to reveal the level of enlightenment of teachers of Arabic language in the basic stage, with the concept of writing and the principles of its learning and teaching, also aimed at investigating whether the level of teachers’ enlightenment concept of writing and the principles of their learning and teaching vary according to two variables (the academic qualification and educational experience).To achieve the goal of the study, a test was built to measure teachers' enlightenmentconcept of writing and the principles of its learning and teaching, The test consisted of (30) items of multiple choice type, After verifying …

Predictive Ability Of Social Intelligence For The Degree Of Applying Leadership Program For Future To The Unrwa School Principals In Jordan المقدرة التنبؤية للذكاء الاجتماعي لدرجة تطبيق مضامين برنامج القيادة من أجل المستقبل لدى مديري مدارس وكالة الغوث الدولية (الاونروا) في الأردن, Suheir Hammad Yacoub, Nawaf Mousa Shatnawi, Eid Mohammad Kanan

Jordanian Educational Journal

Abstract:

The study aimed to reveal the predictive ability of social intelligence for the degree of applying leadership program for future to the United Nations Relief & Work Agency (UNRWA) school principals in Jordan from the teachers point of view. The study employed the analytical descriptive methodology. The population of the study consisted of (4049) male & female teachers from the UNRWA schools, and in order to achieve the goal of the study a sample of (335) male & female teachers were randomly selected. They were chosen by the stratified random sample method. The study tool was presented by two …

Evaluation Of Iron Element By New Cpe Method And (Icp-Ms) In The Wastewater Of The Lifting And Treatment Stations, Mohammed Nasser Hussain, Ahmed Fadhil Khudhair, Hussain Jawad Ahmed

Al-Bahir

A new micell-mediated phase separation technique has been created to preconcentrate levels of iron before measuring it using a UV-Vis spectrophotometer. The method is based on the extraction of iron from the 1-Nitroso-2- naphthol reagent using Triton X-114 in a cloud point extraction procedure, where the method's ideal conditions were attained. 0.2 mL of Triton X-114, 2.887 mmol. L-1 of 1-Nitroso-2-naphthol reagent, pH = 8, 60 ºC. The Iron detection limit for the method is 0.05 µg. mL-1, and the RSD% is 4.728 µg. mL-1. Linearity was maintained in the iron concentration range of 0.25 to 16 µg. mL-1. Furthermore, …

Dance Program To Present Faculty Dance Concert, Taylor University

2023 Website News Stories

No abstract provided.

Using Encrypted Genotypes And Phenotypes For Collaborative Genomic Analyses To Maintain Data Confidentiality, Tianjing Zhao, Fangyi Wang, Richard Mott, Jack Dekkers, Hao Cheng

Department of Animal Science: Faculty Publications

To adhere to and capitalize on the benefits of the FAIR (findable, accessible, interoperable, and reusable) principles in agricultural genome- to-phenome studies, it is crucial to address privacy and intellectual property issues that prevent sharing and reuse of data in research and industry. Direct sharing of genotype and phenotype data is often prohibited due to intellectual property and privacy concerns. Thus, there is a pressing need for encryption methods that obscure confidential aspects of the data, without affecting the outcomes of certain statistical analyses. A homomorphic encryption method for genotypes and phenotypes (HEGP) has been proposed for single-marker regression in …

Cadwallader, Megan, Gretchen Thiele

Querying the Past: LGBTQ Maine Oral History Project Collection

Meghan Cadwallader was born in 1976 in a small, rural town in Upstate New York. She grew up with a stable family and surrounded by the Catholic religion. Cadwallader realized she was lesbian around her junior year of high school. However, her sexuality was never a huge deal, more just another part of her. She went to college at Holland’s University, and all-girls school, in which she initially came out to people resulting in mixed responses. Meghan then went to Bucknell University In Pennsylvania. She received a degree in French and English with a concentration in creative writing. She talks …

Episode 4: Title Ix, Sara Gras

Season 01

This episode picks up where the last left off – about 50 years ago – when Title IX's enactment changed education and athletics for women and girls in some big ways. But this 50 year old statute and implementing regulations were not created with trans and non-binary students in mind. Messaging on how schools must create and adapt policies with these students in mind, including rules about athletic participation, has been inconsistent and confusing. To help address this, amendments to the regulations have been proposed. If these changes are finalized, there will certainly be improvements for trans kids in school, …

Advances And Opportunities In Unraveling Cold-Tolerance Mechanisms In The World's Primary Staple Food Crops, Sofora Jan, Sachin Rustgi, Rutwik Barmukh, Asif B. Shikari, Brenton Leske, Amanuel Bekuma, Darshan L. Sharma, Wujun Ma, Upendra Kumar, Uttam Kumar, Abhishek Bohra, Rajeev K. Varshney, Reyazul Rouf Mir

Grain and Other Field Crops Research Articles

Temperatures below or above optimal growth conditions are among the major stressors affecting productivity, end-use quality, and distribution of key staple crops including rice (Oryza sativa), wheat (Triticum aestivum), and maize (Zea mays L.). Among temperature stresses, cold stress induces cellular changes that cause oxidative stress and slowdown metabolism, limit growth, and ultimately reduce crop productivity. Perception of cold stress by plant cells leads to the activation of cold-responsive transcription factors and downstream genes, which ultimately impart cold tolerance. The response triggered in crops to cold stress includes gene expression/suppression, the accumulation of sugars upon chilling, and signaling molecules, among …

Design Thinking’S Effect On Empathy Development In Middle School English- Language Arts, Kim Starkey

Dissertations

The purpose of this quantitative study was to explore the impact of Design Thinking on students' empathy development in middle school English Language Arts (ELA) classrooms. The study involved two middle school instructors with eight classes, implementing Design Thinking, Reader's Workshop, and traditional ELA curriculum in different combinations (n =102) and two control classes (n =27).

The Adolescent Empathy Measure (AMES) and rubrics for analyzing student writing samples were used to assess changes in empathy. The AMES was given before and after the interventions, and the writing samples were analyzed before and after the interventions as well. The findings indicate …

2023 November 13 - Faculty Senate Agenda And Minutes, Faculty Senate, East Tennessee State University

Faculty Senate Agendas and Minutes

No abstract provided.

The Utah Statesman, November 13, 2023, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Compatibility Investigation Of Waste Plastics In Bitumen Via A Molecular Dynamics Method, Hui Yao, Xin Li, Hancheng Dan, Qingli Dai, Zhanping You

Michigan Tech Publications

The compatibility between waste plastic polymers and bitumen is the most challenging issue hindering the improvement of modified bitumen performance. The current practice of recycled waste plastics includes the use of polyvinyl chloride (PVC), polypropylene (PP), polyethylene (PE), etc. This study was designed to investigate the compatibility of different waste plastic polymers with bitumen binders by conducting molecular dynamics (MD) simulations at different temperatures. The molecular models of these materials were constructed in this study for the compatibility analysis, and they include the base bitumen, polymers (PVC, PP, and PE), polymer- bitumen blending systems. Using the output and related calculations …

Bioelectrocatalytic Synthesis: Concepts And Applications, Dylan G. Boucher, Emily Carroll, Zachary A. Nguyen, Rohit G. Jadhav, Olja Simoska, Kevin Beaver, Shelley D. Minteer

Chemistry Faculty Research & Creative Works

Bio electrocatalytic synthesis is the conversion of electrical energy into value-added products using biocatalysts. These methods merge the specificity and selectivity of biocatalysis and energy-related electrocatalysis to address challenges in the sustainable synthesis of pharmaceuticals, commodity chemicals, fuels, feedstocks and fertilizers. However, the specialized experimental setups and domain knowledge for bio electrocatalysis pose a significant barrier to adoption. This review introduces key concepts of bioelectrosynthetic systems. We provide a tutorial on the methods of biocatalyst utilization, the setup of bioelectrosynthetic cells, and the analytical methods for assessing bio electrocatalysts. Key applications of bio electrosynthesis in ammonia production and small-molecule synthesis …

Catfish Neurocranium, Fiona Smith, Juliana Ottens, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Understanding The Impacts Of Molecular And Macromolecular Crowding Agents On Protein-Polymer Complex Coacervates, Shanta Biswas, Alison L. Hecht, Sadie A. Noble, Qingqiu Huang, Richard E. Gillilan, Amy Y. Xu

Faculty Publications

Complex coacervation refers to the liquid-liquid phase separation (LLPS) process occurring between charged macromolecules. The study of complex coacervation is of great interest due to its implications in the formation of membraneless organelles (MLOs) in living cells. However, the impacts of the crowded intracellular environment on the behavior and interactions of biomolecules involved in MLO formation are not fully understood. To address this knowledge gap, we investigated the effects of crowding on a model protein-polymer complex coacervate system. Specifically, we examined the influence of sucrose as a molecular crowder and polyethylene glycol (PEG) as a macromolecular crowder. Our results reveal …

Swelling Induced Buckling Of Photopatterned Hydrogel Beams, Chinar Yogesh Kokaje

USF Tampa Graduate Theses and Dissertations

The main goal of this study was to learn more about swelling induced buckling of surface-attached gel lines photo-patterned from thermally responsive polymers. A library of 10 different polymer compositions was synthesized using methacryloyloxybenzophenone (MABP) as the photo-cross-linking monomer. For each of the polymers, a series of beam-like patterns were prepared on polystyrene tissue culture dishes by first depositing a known amount of polymer into the tissue culture dish followed by pattern generation using a photo-lithography mask with line widths of 10, 20, 30, 50, and 80 μm. The target height of each polymer line was 100 μm. After development …

Effects Of Aging On Post-Exercise Oxygen Consumption: A Preliminary Study, Steven Klepacz

Health, Exercise, and Sports Sciences ETDs

Aging and excess post-exercise oxygen consumption (EPOC) is something that has not been adequately studied. Studies looking at EPOC mostly are compiled of young college age individuals. Aging in humans is a topic of much research with still more to be learned. The study in this paper attempts to answer the question of whether age affects EPOC when performing a certain exercise. Preliminary findings based on general age-related research suggest the possibility. This thesis will explore the current research related to age and EPOC, analyze the findings, and discuss additional avenues for future research.

Strong Correlations Of Sea Ice Cover With Macroalgal Cover Along The Antarctic Peninsula: Ramifications For Present And Future Benthic Communities, Charles D. Amsler, Margaret O. Amsler, Andrew Klein, Aaron W. Galloway, Katrin Iken, James B. Mcclintock, Sabrina Heiser, Alex T. Lowe, Julie Schram, Ross Whippo

Faculty, Staff, and Students

Macroalgal forests dominate shallow hard bottom areas along the northern portion of the Western Antarctic Peninsula (WAP). Macroalgal biomass and diversity are known to be dramatically lower in the southern WAP and at similar latitudes around Antarctica, but few reports detail the distributions of macroalgae or associated macroinvertebrates in the central WAP. We used satellite imagery to identify 14 sites differing in sea ice coverage but similar in terms of turbidity along the central WAP. Fleshy macroalgal cover was strongly, negatively correlated with ice concentration, but there was no significant correlation between macroinvertebrate cover and sea ice. Overall community (all …

Edwin Pear, Oral History Interview, 2023, Hilary Hill, Matt Jones

Oral Histories

Edwin "Ed" Pear is an attorney with a long distinguished career in real estate, business, and estate planning. Pear attended the Roosevelt school from K-12, and was apart of the graduating class of 1959. In this interview, Ed recounts memories of growing up in a Jewish family in Ypsilanti, his fathers clothing store, and other local businesses that existed at the time. He also reminisces about his time as a student at Roosevelt, sharing his experiences in athletics, extracurriculars, and lamenting about the sadness of the schools closure.

Tim-3 Blockade In Diffuse Intrinsic Pontine Glioma Models Promotes Tumor Regression And Antitumor Immune Memory., Iker Ausejo-Mauleon, Sara Labiano, Daniel De La Nava, Virginia Laspidea, Marta Zalacain, Lucía Marrodán, Marc García-Moure, Marisol González-Huarriz, Irati Hervás-Corpión, Laasya Dhandapani, Silvestre Vicent, Maria Collantes, Iván Peñuelas, Oren J. Becher, Mariella G. Filbin, Li Jiang, Jenna Labelle, Carlos A O De Biagi-Junior, Javad Nazarian, Sandra Laternser, Timothy N. Phoenix, Jasper Van Der Lugt, Mariette Kranendonk, Raoull Hoogendijk, Sabine Mueller, Carlos De Andrea, Ana C. Anderson, Elizabeth Guruceaga, Carl Koschmann, Viveka Nand Yadav, Jaime Gállego Pérez-Larraya, Ana Patiño-García, Fernando Pastor, Marta M. Alonso

Manuscripts, Articles, Book Chapters and Other Papers

Diffuse intrinsic pontine glioma (DIPG) is an aggressive brain stem tumor and the leading cause of pediatric cancer-related death. To date, these tumors remain incurable, underscoring the need for efficacious therapies. In this study, we demonstrate that the immune checkpoint TIM-3 (HAVCR2) is highly expressed in both tumor cells and microenvironmental cells, mainly microglia and macrophages, in DIPG. We show that inhibition of TIM-3 in syngeneic models of DIPG prolongs survival and produces long-term survivors free of disease that harbor immune memory. This antitumor effect is driven by the direct effect of TIM-3 inhibition in tumor cells, the coordinated action …

The Structures And Functions Of Offices Of Academic Affairs: A Case Study, Ryan Thomas Landry

LSU Doctoral Dissertations

This study sought to describe how offices of academic affairs (administrative offices supporting provosts) at public, research-intensive universities in the United States are structured and what kind of work these offices do. There is a dearth of scholarly literature on the topic, indicative of an overall lack of knowledge about these organizations. From a practical standpoint, I intended for this study to contribute to the body of knowledge of higher education administration with hopes that it provides helpful insights to administrators as they consider organizational design. Using the theoretical framework of modern organization theory, I employed an embedded case study …

A Socio-Cultural Analysis Of Work, Love And Family In South Korean Dramas, Emily Stier Adler, Emily Farmer

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.

Plastics And The Environment, I. E. Napper, R. C. Thompson

School of Biological and Marine Sciences

Plastics are persistent and pervasive throughout the environment and have now been reported from the deepest parts of the ocean to the tops of the highest and most remote mountains. There is a body of information on the sources, degradation, and transport of plastics as well as a variety of research investigating the ecotoxicological and wider ecological consequences of plastic ingestion and accumulation. Such knowledge has been obtained with developments in field and laboratory methods for plastic identification and then well-publicized in the media and wider public communications. However, although there has been a large focus on plastic pollution within …

Do Animals Deserve Moral Consideration?, Philosopher's Discussion Group

The Philosopher's Stone

• Do Animals Deserve Moral Consideration?

Cas Connections- 2023 Fall Term, Dean's Office

CAS Connections

No abstract provided.

Cell Of Origin Identification Using Methylation Signatures From Seminal Cell-Free Dna And Heterogenous Cellular Mixtures, Ryan Barney

Theses and Dissertations

Infertility is an issue for approximately 12% of couples attempting to have a child. Of this group, 50% of the cases are due to male factor infertility. There are many reasons for decreased fecundity in men, but there remains 10% to 15% of infertile men that are diagnosed with the most severe form of infertility, non-obstructive azoospermia (NOA). A diagnosis of NOA implies the lack of sperm cells in the ejaculate with no physiological reason. The current diagnostic test and treatment consist of microscopic examination of seminal fluid and a biopsy to extract any viable sperm from the testis. This …

Biodov: A Tool Used To Encourage Discovery In Bioinformatics Through Gamification, Gregory D. Johnson Jr.

Theses

Expressing big data in a meaningful manner is exceptionally difficult. Scientists often struggle with the visualization of data due to several limitations. Currently, many scientists use two-dimensional figures to display and analyze meaningful data. However, I believe using game design theory and game technologies, we can create more robust visualizations. These visualizations will allow scientists to easily communicate science to the masses and make better discoveries. Therefore, we introduce BioDOV (Biological Data Oriented Visualization). This tool will utilize game design principles to expand upon current visualization methods in the scientific community. Through this proof of concept, we will create the …