Digital Commons Network^™

Treatment Of Allergic Rhinitis: Diphenhydramine Vs. Fexofenadine, Lauren Setzer

Undergraduate Honors Theses

Allergic rhinitis is a growing allergic illness brought on by the inhalation of allergens, resulting in a list of symptoms, including sneezing, watery eyes, runny nose, etc. Among the many treatment options available, H1-antihistamines are a popular choice for allergic rhinitis sufferers. First-generation antihistamines were the first to hit the market and were later discovered to be lipophilic, causing blood-brain barrier penetration and cognitive impairment. Second-generation antihistamines were later developed with lipophobic properties to eliminate any form of cognitive impairment. Both generations are readily available over-the-counter in tablet form, including two commonly used ones: diphenhydramine (Benadryl®) and fexofenadine (Allegra®). These …

Huntington’S Disease: A Systematic Review And Overview Of Treatments, Madison Mintz

Undergraduate Honors Theses

Huntington’s Disease (HD) is a genetic neurodegenerative disease that is the result of a mutation of the huntingtin gene. The gene is passed in an autosomal dominant fashion and is the result of multiple Cystine, Adenine, and Guanine base repeats. HD symptoms manifest as motor, cognitive, and psychological symptoms that can range of chorea movements to depression or apathy. The disease progresses through various prodromal and clinical stages as the disease starts to manifest. The current technique to diagnose HD is the use of direct genetic testing, which counts the number of repeats. Due to the nature of HD, both …

The Covid-19 Pandemic And Its Influence On The Human Immune System, Nicole L. Riha

Undergraduate Honors Theses

COVID-19 rapidly infected the world, and scientists continue to research how the disease spread and killed as many as it did by analyzing how it affects the human immune system and referring to past pandemics. Since the pandemic is ongoing, scientists do not fully understand how the virus works and if lockdowns were effective. Nevertheless, a discussion on what is known about COVID-19's influence on the human immune system is needed. With an understanding of the COVID-19 pandemic, scientists can make more effective treatments for COVID-19 and learn how to manage future pandemics.

Nsaids And Oral Drug Absorption: Ibuprofen Through A Pharmacokinetic Lens, Courtney Gant

Undergraduate Honors Theses

Human pharmacokinetics is the study of how administered medications move throughout and behave within the body. Absorption, distribution, metabolism, and excretion are four integral parts of this field of study and are commonly known as the ADME principles of pharmacokinetics, but other processes are studied within the field. For orally administered drugs, the absorption process lies within the small intestine and colon, two components of the gastrointestinal (GI) tract; this bodily system is associated with many variables––many of which must be considered in the study of oral drug absorption. Often administered orally, non-steroidal anti-inflammatory drugs (NSAIDs) make up a group …

Porifera: Biology And Medicinal Properties, Emma L. Rayfield

Undergraduate Honors Theses

The focus of this thesis is the possibility of oceanic medicine through understanding the general biology of poriferans, their symbionts, medicinal properties, and how we could harvest sponges conservatively. It was necessary to understand the basic biology of poriferans regarding their structures, differences in their classes, and how they obtain nutrition, develop, and reproduce. The ecology of the poriferans was also researched including their larval and sessile stages and how their environment determines where they settle. Additionally, ecology was examined including how poriferans interact with symbionts and other organisms. This then was utilized to seek whether poriferans had useful medical …

Genome Sequence Of Subcluster L3 Mycobacterium Smegmatis Mc2155 Phage Duncansleg, Megan Cevasco, Kaitlynn Burbage, Connor Hadwin, Edenborough Hibionada, Kirsten Presnell, Daniel Williams

Biology

Bacteriophage DuncansLeg is a siphovirius isolated in 2021 from soil on the Coastal Carolina University campus in Conway, South Carolina, using the host Mycobacterium smegmatis mc²155. DuncansLeg has a 75,593-bp circular genome that contains 126 predicted protein-coding genes and 10 tRNA genes. DuncansLeg is assigned to actinobacteriophage cluster L3.

Genome Sequences Of Six Cluster Ct And Two Cluster Dj Bacteriophages That Infect Gordonia Rubripertincta, Xavier F. Rodriguez, Daniel C. Williams, Catherine P. Chia

Biology

We report the genome sequences of eight bacteriophages isolated using Gordonia rubripertincta NRRL B-16540-SEA. Based on gene content similarity to phages in the Actinobacteriophage database, six of the phages are assigned to phage cluster CT while two are assigned to cluster DJ.

An Examination Of The Utilization Of Bloom's Taxonomy In School-Based Biology Assessment Tasks In Selected Secondary Schools Meru District, Tanzania, Agatha Wilson Yintore

Master of Education

The world’s current most significant demand is for training many scientists and different science professionals. As a result, the preparation has always started at deficient learning levels, such as primary and secondary schools. In Tanzania, other science subjects are taught in secondary schools; among them, biology is included, and it is the only mandatory science subject in secondary school. Different approaches to teaching have been employed to ensure that the learners grasp the knowledge and skills of the subject. However, the examination results over the years have not been of high and promising performance, and different reasons are suspected to …

Examining The Management Of Second Chance Schools: A Case Study Of Secondary School For Teen Mothers In Kenya, Nancy Chebet

Master of Education

Teen pregnancy in Kenya is on the increase and is widely attributed to the prolonged closure of schools because of the COVID-19 pandemic, and widespread exposure to irresponsible sexual behaviours and exploitation. Approximately 13,000 girls dropped out of school in 2021 due to teenage pregnancies. However, since children command the right to education and education is a priority in sustainable development goals, the feminist movement has established ways to ensure teen mothers are educated, in Kenya, there is the rise of schools designated for teen mothers. Therefore, the study sought to examine how these schools are managed this is because …

Overcrowded Classrooms: Assessment And Evaluation Strategies By Science Secondary School Teachers In Kericho County- Kenya, Rutoh Dominic

Master of Education

This study investigated how science teachers have successfully conducted assessment and evaluation in overcrowded classrooms due to 100% transition in Kenya, and particularly, in Kericho County. Two objectivities guided the study: - to find out the strategies used by science teachers to conduct assessment and evaluation and to determine how science teachers cope with assessment and evaluation challenges in overcrowded classrooms. Purposive sampling was used to selected five science teachers instructing form three class in the sampled school. Simple random sampling was used to select 12 students who participated in the study to ensure everyone got a chance to be …

Annual Report Of The Registrar 2022/2023, University Of Northern Iowa

Institutional Effectiveness & Planning Documents

Contents:

--Definitions
--Some Comparisons
--Annual Report Data
--Summary of Attendance
--Attendance by Session
--Degrees Granted 2022/23
--Degree Summary 2022/23
--Program Certificates 2022/23
--Miscellaneous Enrollment Information
--Degrees Granted by College, Degree and Racial/Ethnic Classification

Sticks And Stones May Break Bones, But Only The Right Words Can Protect Human Rights: An Examination Of The Convention On The Rights Of Persons With Disabilities In Relation To Psychosocial Disabilities, Dailyah Rudek

Denver Journal of International Law & Policy

The U.N. Convention on the Right of Persons with Disabilities (CRPD) is the most progressive document of its kind, containing admirable principles and mechanisms to protects the rights of people with physical disabilities and outlining international expectations regarding their treatment. Unfortunately, the instrument is woefully inadequate with respect to psychosocial disability and is leaving millions of people worldwide without sufficient protection. Future international conventions on human rights should specifically address persons with psychosocial disability and the CRPD must either be amended to appropriately address these disabilities or have such disabilities severed from its applicability as a new psychosocial-specific convention is …

Sleep Quality, Daytime Sleepiness, And Insomnia In Patient With Epilepsy: A Single Center Experience From Saudi Arabia, Asmaa A. Alenizi, Alaa M. Eskandrani, Safiyyah A. Asiri, Fawaiyzah A. Ba Maqdom, Majed H. Al Hameed, Rayan A. Al Harbi, Moneera O. Aldraihem, Mubarak M. Aldosari

Neurosciences

Objectives: To measure the burden of insomnia and daytime sleepiness (DTS) and their effects on sleep quality, and the risk factors of poor quality of sleep. Methods: We conducted a cross-sectional study of 218 epilepsy patients. We administered well-validated and previously translated questionnaires to assess sleep quality, insomnia, and DTS using the Pittsburgh Sleep Quality Index, Insomnia Severity Index, and Epworth Sleepiness Scale, respectively. Results: Approximately 75% of participants reported poor sleep quality. Moreover, 42.2% did not have insomnia, while 37.6%, 17.9%, and 2.3% had subthreshold insomnia and clinical insomnia of moderate and severe severity, respectively. Roughly 64.2% of participants …

Prevalence Of Post-Covid Symptoms Of Obsessive-Compulsive Disorder In Saudi Arabia, Mohammed A. Alblowi, Waleed M. Alkhammash, Thamer M. Alzahrani, Mohammed H. Hakeem, Saeed A. Alsarar, Abdulhadi A. Alqahtani, Abdulrahman M. Almutairi, Turki H. Al Binhar

Neurosciences

Objectives: To determine the prevalence of Obsessive-Compulsive Disorder (OCD) symptoms in patients who have survived COVID-19. Methods: The study used an observational cross-sectional design between July and October 2021. The target population was adult patients who had confirmed COVID-19 infection prior to joining the study, OCD symptoms were assessed using the Arabic OCD scale created by Abohendy and colleagues, which included 83 questions covering 12 different domains and was administired online. Results: A total of 356 patients were included in the analysis. Approximately 9.0% and 1.7% of the patients had a history of psychiatric disease and OCD diagnosis (respectively). The …

The Clinicopathological Features And Prognosis Of Multifocal High-Grade Gliomas In Adults With H3f3a Mutation, Yongrui Zhao, Yidong Chen, Leiming Wang, Ying Gao, Jiankun Xu

Neurosciences

Objectives: To explore the clinicopathological features and prognosis of multifocal high-grade gliomas (M-HGGs) with H3F3A mutation in adults. Methods: Four adult patients with H3F3A -mutant M-HGGs who were treated at our institution from August 2020 to December 2021 were reviewed, including clinical, pathological and radiologic data. A series of 16 adult patients with M-HGGs without H3F3A mutation was used as a comparative group. Progression-free survival (PFS) and overall survival (OS) were compared between the groups using the Kaplan–Meier method. Results: All patients were IDH wild-type and TERT wild-type, and P53 was overexpressed. A patient with the H3 G34R mutation and …

Effects Of A Psychological Stressor On Methamphetamine Seeking In Rats., Kayla B. Cox

Psychology ETDs

Although methamphetamine abuse and fatality rates are on the rise in the United States, there are currently no FDA approved drugs to treat methamphetamine use disorder (MUD). To better understand factors contributing to addiction, researchers have designed various rodent models of stress including the use of footshock, social defeat and maternal separation, however, these models involve physical or early life stress exposure and thus are less translatable to human psychological stress. The present study implemented predatory odors as a model of psychological stress and examined whether chronic exposure to these stressors enhanced subsequent vulnerability to a subthreshold dose of methamphetamine. …

Clinical Research On Transcatheter Aortic Valve Replacement For Bicuspid Aortic Valve Disease: Principles, Challenges, And An Agenda For The Future, Yousif Ahmad, Mahesh V. Madhavan, Suzanne J. Baron, John K. Forrest, Michael A. Borger, Jonathon A. Leipsic, João L. Cavalcante, Dee Dee Wang, Patrick Mccarthy, Molly Szerlip, Samir Kapadia, Raj Makkar, Michael J. Mack, Martin B. Leon, David J. Cohen

Cardiology Articles

Bicuspid aortic valve disease (BAVD) is present in up to half of all patients referred for surgical aortic valve replacement (SAVR) yet was an exclusion criterion for all randomized controlled trials (RCTs) comparing transcatheter aortic valve replacement (TAVR) to SAVR. Nonetheless, approximately 10% of patients currently treated with TAVR have BAVD and available observational data for performing TAVR in these patients are limited by selection bias. Many in the cardiovascular community have advocated for RCTs in this population, but none have been performed. The Heart Valve Collaboratory (HVC) is a multidisciplinary community of stakeholders with the aim of creating significant …

Interagency Dynamics In Matters Of Health And Immigration, Medha D. Makhlouf

Faculty Scholarly Works

When Congress delegates authority to an executive agency, it tells us something important about the expertise that Congress wishes to harness in policymaking on an issue. In the legal literature on interagency dynamics and cooperation, issues at the nexus of health and immigration are largely understudied. This Article extends this literature by examining how delegations of authority on issues at the intersection of health and immigration influence policymaking. In an analysis of how administrative law models apply to three topics in the shared regulatory space of the Department of Health and Human Services (“HHS”) and the Department of Homeland Security …

Abet To Ku Peos To Mission Vision Values, Kettering University

Assurance Argument Evidence Files

No abstract provided.

Bright Future Update, Kettering University

Assurance Argument Evidence Files

No abstract provided.

Asc Tutoring Schedule, Kettering University

Assurance Argument Evidence Files

No abstract provided.

News Model Un Story, Kettering University

Assurance Argument Evidence Files

No abstract provided.

Syl Alternative To Thesis, Kettering University

Assurance Argument Evidence Files

No abstract provided.

Web Chme Program Page, Kettering University

Assurance Argument Evidence Files

No abstract provided.

Hostos Community College Academic Bulletin 2022-2023, Hostos Community College

College Bulletins

This is the official college catalog for 2022-2023. It contains course descriptions as well as information on degree programs, college resources and services, financial aid, admissions, and the academic calendar.

Effects Of Self-Adhesive Resin Cements Cured With Different Light Sources On Human Gingival Fibroblasts, Siriwong Wongsirisuwan

Chulalongkorn University Theses and Dissertations (Chula ETD)

Improperly polymerized self-adhesive resin cements (SARCs) can lead to adverse effects such as periodontitis or peri-implantitis. This in vitro study investigated the effect of 2 light-polymerizing units (LPUs) on the physical and chemical properties of 2 SARCs under varying simulated clinical scenarios and the responses of primary human gingival fibroblasts (hGFs) exposed to such procedures. Dental cement discs of SARCs (depth=2 mm, diameter=5 mm) were prepared with cylindrical acrylic molds. Kerr DemiPlus and 3M Elipar DeepCure-S LED LPUs were used to polymerize 2 different SARCs (RelyX U200 and Maxcem Elite Chroma). The polymerization protocols were either directly light-polymerized or through …

Network Structure And Network Effectiveness In Thailand's Provincial Covid-19 Response Networks, Ruechagorn Trairatananusorn

Electronic Theses and Dissertations, 2020-2023

Health and well-being are key focuses for international organizations and governments around the world as one of the United Nations' (UN) Sustainable Developmental Goals (SDGs). The emergence of COVID-19 pandemic since late 2019 has led to not only substantial life losses, but also negative social and economic impacts that are relatively comparable to the "Spanish Flu" pandemic. The insights from public administration literature suggested that emergency and crisis management require collaborative efforts from various stakeholders across sectors and levels. However, the existing literature that studied the COVID-19 pandemic response under network perspective is still scarce in developing countries, especially in …

Assessing The Patient Experience Evaluation Methodology: A Review Of The Hcahps Survey And Related Processes, Michael Molta

Full-Text Theses & Dissertations

The healthcare industry has undergone substantial changes that influence how hospitals evaluate success. Legislation from the Centers for Medicare and Medicaid Services (CMS.gov, 2023) that informs reimbursement levels of patient populations in all U.S. hospitals require organizations to focus on patient experiences, more specifically on scores from the Hospital Consumer Assessment of Healthcare Providers and Systems Survey, referred to as HCAHPS (pronounced H-caps). The Consumer Assessment of Healthcare Providers and Systems Survey or CAHPS® Hospital Survey or Hospital CAHPS® (CAHPS ® is a registered trademark of the Agency for Healthcare Research and Quality). This standardized survey instrument and data collection …

Understanding And Application Of Systems Thinking To Diversity Challenges At Higher Education Institutions, Odell Jones

Full-Text Theses & Dissertations

This research argues that establishing and sustaining leadership diversity within Higher Education Institutions (HEIs) is a complex-systems challenge and that those responsible for leading efforts to establish and sustain diversity, referred to as DEI leaders, should adopt a mindset of systems thinking and apply problem-solving methods and tools informed by systems thinking. Semi-structured interviews with DEI Leaders at HEIs were conducted regarding background and perceptions of their work, and how they thought about and made choices concerning diversity challenges. Interview questions were designed to gain an understanding of the degree to which these leaders think about DEI and if they …

Respiratory Therapy Staff Retention: A Systems Thinking Approach, Jerin G. Juby

Full-Text Theses & Dissertations

Respiratory therapists are an integral part of the healthcare workforce in the United States. The healthcare workforce shortage accelerated by the COVID global pandemic has impacted respiratory therapy departments across the nation, with organizations struggling to hire and retain staff. The prevailing approaches in combating this is linear in nature and does not consider the complexity of the system. The purpose of this dissertation is to address retention issues in respiratory therapy departments from a systems thinking approach and to develop a prototype utilizing systems thinking methodologies and tools.