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2023

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Assessing Undergraduate Expressions Of Biochemical Mechanisms, Lauren Alaina Richardson Dec 2023

Assessing Undergraduate Expressions Of Biochemical Mechanisms, Lauren Alaina Richardson

Honors Capstone Projects and Theses

No abstract provided.


Lew.Wr1 Rats Develop Non-Alcoholic Steatohepatitis: Does Fat10 Play A Role In Steatosis Development, Christopher Riley Apperson Dec 2023

Lew.Wr1 Rats Develop Non-Alcoholic Steatohepatitis: Does Fat10 Play A Role In Steatosis Development, Christopher Riley Apperson

Honors Capstone Projects and Theses

No abstract provided.


Recommendation Of Intermittent Fasting In The Treatment Of Chronic Musculoskeletal Pain: Evaluating Healthcare Provider Behavior And Patient Fasting Behavior., Melissa Humphreys, Melissa Humphreys Dec 2023

Recommendation Of Intermittent Fasting In The Treatment Of Chronic Musculoskeletal Pain: Evaluating Healthcare Provider Behavior And Patient Fasting Behavior., Melissa Humphreys, Melissa Humphreys

Doctor of Nursing Practice Papers

Abstract

Background: Chronic musculoskeletal pain was a significant problem in this primary care clinic. A total of 75% of the primary care providers (PCPs) agreed to consider an alternative treatment for chronic pain and Intermittent fasting (IF) was introduced as an option.

Purpose: Quality improvement project to introduce IF as an adjunct to traditional pain management for chronic musculoskeletal pain, evaluate PCPs’ application, and patient response to provider recommendation of IF.

Methods: A virtual continuing education (CE) program on IF was presented to PCPs in family medicine to establish baseline competency. For two months, 29 patients were recommended IF who …


Investigation Of Physicochemical Properties, Nutritional Status, And Volatile Compounds Profiling Of Four Underutilized Spices Of Cameroon Origin, Stève Djiazet, Digambar Kavitake, Ramasamy Ravi, Laurette B. Mezajoug Kenfack, Ragu Pullakhandam, Bethala L.A. Prabhavathi Devi, Clergé Tchiégang, G. Bhanuprakash Reddy, Prathapkumar Halady Shetty Dec 2023

Investigation Of Physicochemical Properties, Nutritional Status, And Volatile Compounds Profiling Of Four Underutilized Spices Of Cameroon Origin, Stève Djiazet, Digambar Kavitake, Ramasamy Ravi, Laurette B. Mezajoug Kenfack, Ragu Pullakhandam, Bethala L.A. Prabhavathi Devi, Clergé Tchiégang, G. Bhanuprakash Reddy, Prathapkumar Halady Shetty

Agricultural and Environmental Sciences Faculty Research

In this study, four underutilized spices (fruit and ulb of Aframomum sulcatum, fruit of Xylopia africana, and bark of Hypodaphnis zenkeri) were analyzed for their physical properties, nutrients composition, and profile of volatile compounds using standard analytical methods. The protein, fat, sugar, and dietary fiber contents were analyzed. The spices were revealed to be a good source of essential amino acids and fatty acids including pentadecanoic acid. Several minerals (Mn, Mg, Ca, Fe, and K) of nutritional importance were found at various proportions. Electronic nose analysis revealed the presence of fifty-six different compounds, belonging to ten major classes (phenylpropenes, acids, …


Bingroup2: Statistical Tools For Infection Identification Via Group Testing, Christopher R. Bilder, Brianna D. Hitt, Brad J. Biggerstaff, Joshua M. Tebbs, Christopher S. Mcmahan Dec 2023

Bingroup2: Statistical Tools For Infection Identification Via Group Testing, Christopher R. Bilder, Brianna D. Hitt, Brad J. Biggerstaff, Joshua M. Tebbs, Christopher S. Mcmahan

Department of Statistics: Faculty Publications

Group testing is the process of testing items as an amalgamation, rather than separately, to determine the binary status for each item. Its use was especially important during the COVID-19 pandemic through testing specimens for SARS-CoV-2. The adoption of group testing for this and many other applications is because members of a negative testing group can be declared negative with potentially only one test. This subsequently leads to significant increases in laboratory testing capacity. Whenever a group testing algorithm is put into practice, it is critical for laboratories to understand the algorithm’s operating characteristics, such as the expected number of …


Community Acquired Pneumonia Antibiotic Duration, Children's Mercy Kansas City Dec 2023

Community Acquired Pneumonia Antibiotic Duration, Children's Mercy Kansas City

Clinical Critically Appraised Topics

No abstract provided.


Good Practices And Common Pitfalls In Climate Time Series Changepoint Techniques: A Review, Robert B. Lund, Claudie Beaulieu, Rebecca Killick, Qiqi Lu, Xueheng Shi Dec 2023

Good Practices And Common Pitfalls In Climate Time Series Changepoint Techniques: A Review, Robert B. Lund, Claudie Beaulieu, Rebecca Killick, Qiqi Lu, Xueheng Shi

Department of Statistics: Faculty Publications

Climate changepoint (homogenization) methods abound today, with a myriad of techniques existing in both the climate and statistics literature. Unfortunately, the appropriate changepoint technique to use remains unclear to many. Further complicating issues, changepoint conclusions are not robust to perturbations in assumptions; for example, allowing for a trend or correlation in the series can drastically change changepoint conclusions. This paper is a review of the topic, with an emphasis on illuminating the models and techniques that allow the scientist to make reliable conclusions. Pitfalls to avoid are demonstrated via actual applications. The discourse begins by narrating the salient statistical features …


Odorant Binding Causes Cytoskeletal Rearrangement, Leading To Detectable Changes In Endothelial And Epithelial Barrier Function And Micromotion, Annabella Nilon Dec 2023

Odorant Binding Causes Cytoskeletal Rearrangement, Leading To Detectable Changes In Endothelial And Epithelial Barrier Function And Micromotion, Annabella Nilon

Honors Theses

Non-olfactory cells have excellent biosensor potential because they express functional olfactory receptors (ORs) and are non-neuronal cells that are easy to culture. ORs are G-protein coupled receptors (GPCRs), and there is a well-established link between different classes of G-proteins and cytoskeletal structure changes affecting cellular morphology that has been unexplored for odorant sensing. Thus, the present study was conducted to determine if odorant binding in non-olfactory cells causes cytoskeletal changes that will lead to cell changes detectable by electric cell-substrate impedance sensing (ECIS). To this end, we used the human umbilical vein endothelial cells (HUVECs), which express OR10J5, and the …


Shoreline Adaptation And The P U Bl I C Trust Protecting California’S Public Trust Resources From Sea Level Rise, California State Lands Commission Dec 2023

Shoreline Adaptation And The P U Bl I C Trust Protecting California’S Public Trust Resources From Sea Level Rise, California State Lands Commission

State & Federal Reports and Publications

The coastal shorelines managed by the State Lands Commission are impacted by climate change, upland development, and natural fluctuations in coastal processes. This report is intended to help the Commission update its leasing practices related to shoreline protection structures and management of coastal state lands and Public Trust resources.


Financial Market Index Prediction Using Machine Learning, Abdelgalal O. I. Abaker, Abdalla S. Mahmoud, Abdalla. Ahmed, Ali Rashash R Alzahrani, Adil. O. Y. Mohamed, Azhari A. Elhag Dec 2023

Financial Market Index Prediction Using Machine Learning, Abdelgalal O. I. Abaker, Abdalla S. Mahmoud, Abdalla. Ahmed, Ali Rashash R Alzahrani, Adil. O. Y. Mohamed, Azhari A. Elhag

Journal of Statistics Applications & Probability

The present work aims to tackle the crucial objective of forecasting values for a range of financial market indices in order to maximize income while minimizing potential losses. This study utilizes a comparative analysis approach to examine the performance of artificial neural networks (ANNs) and decision tree models in predicting stock market movements in Saudi Arabia (KSA). The analysis is conducted using a daily database. The predictive models included in this study are constructed using historical stock market data, which encompasses the time period from January 1, 2013, to October 4, 2023. The primary objective of these models is to …


The Broadwater Formation (Pliocene) Of Nebraska And Southeastern Wyoming, Robert F. Diffendal Jr., James B. Swinehart Dec 2023

The Broadwater Formation (Pliocene) Of Nebraska And Southeastern Wyoming, Robert F. Diffendal Jr., James B. Swinehart

Robert F. Diffendal, Jr., Publications

The Broadwater Formation, initially defined in 1945, is a Pliocene-aged coarse-grained alluvial deposit in Nebraska and southeastern Wyoming. It is characterized by a complex stratigraphic history and debated geologic interpretations. The formation is a rich resource of groundwater for the citizens of Nebraska and the Central Great Plains. We aim to synthesize and redefine the Broadwater Formation, shedding light on its distribution, geological characteristics, and paleoenvironmental significance. While historical hypotheses on Broadwater Formation paleovalley trajectories suggested northwest-southeast trending valleys, later investigations proposed wind-driven erosional patterns to explain the unique topographic features observed. The Broadwater is divided into an unnamed Upper …


Vessel Strike Prevention Measures For Marine Animals And Their Effectiveness, Brock Garrison Busby Dec 2023

Vessel Strike Prevention Measures For Marine Animals And Their Effectiveness, Brock Garrison Busby

Honors Capstone Projects and Theses

No abstract provided.


Editorial: Amaranthus: Naturally Stress-Resistant Resources For Improved Agriculture And Human Health, Volume Ii, Matthew W. Blair, Chance Riggins, Ana Paulina Barba De La Rosa Dec 2023

Editorial: Amaranthus: Naturally Stress-Resistant Resources For Improved Agriculture And Human Health, Volume Ii, Matthew W. Blair, Chance Riggins, Ana Paulina Barba De La Rosa

Agricultural and Environmental Sciences Faculty Research

No abstract provided.


Using Remote Sensing To Determine Riparian Resilience In Beaver Dammed Versus Un-Dammed Corridors Following Whiplash Weather, Sophie Charlotte Valérie Aubry Dec 2023

Using Remote Sensing To Determine Riparian Resilience In Beaver Dammed Versus Un-Dammed Corridors Following Whiplash Weather, Sophie Charlotte Valérie Aubry

Master of Science in Environmental Sciences and Management Projects

Beaver complexes slow and store water allowing for riparian growth which in turn fosters biodiversity, retains carbon, and enhances resistance to fires and drought. Given the benefits associated with beaver complexes and the potential they have for climate mitigation, California hopes to reintroduce beavers and restore their habitat throughout the state. However, the impact of high peak flow events on beaver complexes and their adjacent riparian corridors is less understood and requires more documentation at various spatial scales. To better understand the potential beavers may have as climate change mitigators it is important to understand beaver complex resiliency following a …


Uncrewed Aerial Vehicle Radiometric Calibration: A Comparison Of Autoexposure And Fixed‐Exposure Images, G. Cody Bagnall, John Alex Thomasson, Chenghai Yang, Tianyi Wang, Xiongzhe Han, Chao Sima, Anjin Chang Dec 2023

Uncrewed Aerial Vehicle Radiometric Calibration: A Comparison Of Autoexposure And Fixed‐Exposure Images, G. Cody Bagnall, John Alex Thomasson, Chenghai Yang, Tianyi Wang, Xiongzhe Han, Chao Sima, Anjin Chang

Agricultural and Environmental Sciences Faculty Research

Remote sensing with uncrewed aerial vehicles (UAVs) is increasingly being used in agriculture to provide data on the physical characteristics of plants under field conditions. Data accuracy is critical for decision making with a high degree of confidence. In this work, we compared two multispectral camera calibration methods for image data collected with a UAV: (1) an autoexposure method that relies on a single calibration panel and a post hoc calibration, and (2) a fixed-exposure system that uses three in-field gray calibration panels using the empirical line calibration method. Both methods were compared to reflectance data from (a) four ground …


Increasing Racial Diversity In The North American Plant Phenotyping Network Through Conference Participation Support, David Lebauer, Alexander Bucksch, Jennifer Clarke, Jesse Potts, Sonali Roy Dec 2023

Increasing Racial Diversity In The North American Plant Phenotyping Network Through Conference Participation Support, David Lebauer, Alexander Bucksch, Jennifer Clarke, Jesse Potts, Sonali Roy

Agricultural and Environmental Sciences Faculty Research

A key goal of the North American Plant Phenotyping Network (NAPPN) annual conference is to cultivate a new generation of scientists from diverse backgrounds. As part of their effort to diversify the plant phenomics research community, NAPPN acquired funding to cover all attendance costs for participants from historically black colleges and universities (HBCU) for the 2022 annual meeting. Seven award recipients represented the first attendees from HBCUs in the conference's 6-year history. In this commentary, we report on the impact of the conference awards, including lessons learned, and the future of the award.


Effects Of Sewage Sludge Treatments On Plant Nutrients, Heavy Metals And Tall Fescue(Festuca Arundinacea Schreb.), Ali̇ Riza Ongun, Mahmut Tepeci̇k, Hüseyi̇n Hüsnü Kayikçioğlu, Sezai̇ Deli̇bacak, Tanay Bi̇ri̇şçi̇, Erden Aktaş, Ayşe Kalayci Önaç, Gökhan Balik Dec 2023

Effects Of Sewage Sludge Treatments On Plant Nutrients, Heavy Metals And Tall Fescue(Festuca Arundinacea Schreb.), Ali̇ Riza Ongun, Mahmut Tepeci̇k, Hüseyi̇n Hüsnü Kayikçioğlu, Sezai̇ Deli̇bacak, Tanay Bi̇ri̇şçi̇, Erden Aktaş, Ayşe Kalayci Önaç, Gökhan Balik

Turkish Journal of Agriculture and Forestry

This study was conducted to investigate the effects of anaerobically stabilized sewage sludge (SS) converted into 90% dryness granules at different doses of control, 3% SS, 6% SS, and 9% SS on elemental composition of Festuca arundinacea Schreb. and physicochemical properties of soil. Color measurements were made with the CIE L* a* b* method unit; the highest color (4.10) and the highest coating score (5.7) were calculated for the 6% SS treatment. The highest biomass (9.11 g) was obtained from the 3% SS and the lowest (7.67 g) from the 9% SS dose. Plant height measurements were listed as follows: …


The Effects Of Different Seeding Rates On Nitrogen Acquisition In Pea–Wheat Intercropping, Aybegün Ton, Erik Steen Jensen Dec 2023

The Effects Of Different Seeding Rates On Nitrogen Acquisition In Pea–Wheat Intercropping, Aybegün Ton, Erik Steen Jensen

Turkish Journal of Agriculture and Forestry

Intercropping may improve the use of environmental resources in low-input agricultural systems compared to sole crops and it is possible that risk may be reduced in intercropping, leading to more stable yields and weed control. The aim of the present study was to determine the effect of seeding rate of a normal leafed cultivar and a semileafless pea cultivar (Pisum sativum L.) grown as sole crops, cultivar mixture, and in double and triple intercrops with spring wheat (Triticum aestivum L.) on competitive dynamics, yield and use of nitrogen sources from soil, and symbiotic N2 fixation. A randomized complete blocks experiment …


Soil Burn Severity And Environmental Covariate Effects On Soil Health Two Years Postfire In The Sierra Nevada, Julie A. Lewis Dec 2023

Soil Burn Severity And Environmental Covariate Effects On Soil Health Two Years Postfire In The Sierra Nevada, Julie A. Lewis

Master of Science in Environmental Sciences and Management Projects

Wildfires have been steadily increasing in both size and severity in recent decades. This global trend is most evident in California, especially the North Coast and Sierra Nevada. Although these trends are rising, there is little known about the effects of these wildfires on forest soils. Soil is the 2nd largest C sink on the planet, and the largest terrestrial bank. Without understanding the implication of rising wildfire severities on these soils, we cannot understand how to help protect this resource in the future. Due to the rapid increase in wildfire size and intensity, there is little known about the …


Perceptions Of Stress In Community Clinic Nurses During The Covid-19 Pandemic, Jomeka Smith Dec 2023

Perceptions Of Stress In Community Clinic Nurses During The Covid-19 Pandemic, Jomeka Smith

Dissertations

The COVID-19 pandemic is one of the largest healthcare crises that has affected the entire healthcare industry. Community health nurses in the front-line roles are greatly threatened by the COVID-19 pandemic that has decimated healthcare systems. The well-being of nurses is vital to perform their full potential of adequate patient care. Increased demands and pandemic related stressors can increase the risk of mental health problems. Nurses work in a variety of healthcare settings, however, the expectations, the fear of the unknown, and changes in demands have largely contributed to the unprecedented stressors that accompany nurses in clinical settings. Stress among …


Hand-Use Preferences For Reaching And Object Exploration In Children With Impaired Upper Extremity Functioning: The Role Of Environmental Affordances, Iryna Babik, Michele A. Lobo Dec 2023

Hand-Use Preferences For Reaching And Object Exploration In Children With Impaired Upper Extremity Functioning: The Role Of Environmental Affordances, Iryna Babik, Michele A. Lobo

Psychological Sciences Faculty Publications and Presentations

Infants and young children with weakened or impaired upper extremity functioning often develop a strong hand-use “preference” for reaching and object manipulation. While “preferring” their stronger hand, they often partially or completely ignore their “non-preferred” hand. Such manual lateralization might impede complex object exploration, which would negatively affect children’s cognitive development. The question is whether environmental affordances would significantly affect children’s manifested hand-use “preferences” by promoting the use of the “non-preferred” hand. The current sample included 17 children (5 males; 13.9 ± 8.7 months at baseline) with arthrogryposis multiplex congenita (arthrogryposis). The reaching and object exploration of the children were …


The Effect Of Pesticide Spray Season And Residential Proximity To Agriculture On Glyphosate Exposure Among Pregnant People In Southern Idaho, 2021, Cynthia L. Curl, Carly Hyland, Meredith Spivak, Lianne Sheppard, Bruce Lanphear, Michael N. Antoniou, Maria Ospina, Antonia M. Calafat Dec 2023

The Effect Of Pesticide Spray Season And Residential Proximity To Agriculture On Glyphosate Exposure Among Pregnant People In Southern Idaho, 2021, Cynthia L. Curl, Carly Hyland, Meredith Spivak, Lianne Sheppard, Bruce Lanphear, Michael N. Antoniou, Maria Ospina, Antonia M. Calafat

Public and Population Health Faculty Publications and Presentations

Background: Glyphosate is one of the most heavily used pesticides in the world, but little is known about sources of glyphosate exposure in pregnant people living in agricultural regions.

Objective: Our objective was to evaluate glyphosate exposure during pregnancy in relation to residential proximity to agriculture as well as agricultural spray season.

Methods: We quantified glyphosate concentrations in 453 urine samples collected biweekly from a cohort of 40 pregnant people in southern Idaho from February through December 2021. We estimated each participant’s glyphosate exposure as the geometric mean (GM) of glyphosate concentrations measured in all samples (average n = 11 …


Ionically Crosslinked Cellulose Nanocrystals By Metal Nitrates For The Preparation Of Stable Emulsions With Tunable Interface Properties, Joseph Batta-Mpouma, Gurshagan Kandhola, Jin-Woo Kim Dec 2023

Ionically Crosslinked Cellulose Nanocrystals By Metal Nitrates For The Preparation Of Stable Emulsions With Tunable Interface Properties, Joseph Batta-Mpouma, Gurshagan Kandhola, Jin-Woo Kim

Materials Science and Engineering Faculty Publications and Presentations

Biologically extracted cellulose nanocrystals (CNCs) are rod-like and amphiphilic materials with surface-exposed (hydrophilic sites) and hidden (hydrophobic sites) hydroxyl groups. These physicochemical characteristics make CNCs suitable for use as emulsifying agents to stabilize emulsions. Stable oil-in-water emulsions, using sulfated (i.e., – SO3−) CNCs that were ionically crosslinked with alkaline-earth (i.e., Mg 2+) or transition-d-block (i.e., Zn 2+) metal cations, were developed without the use of any synthetic surfactants or prior functionalization of pure CNCs with hydrophobic molecules. Various emulsion surface properties such as interfacial tension, surface charge, surface chemistry, as well as rheology were characterized. Ionically …


Exploring Artist Residencies For Academic Libraries, Jenne M. Klotz Dec 2023

Exploring Artist Residencies For Academic Libraries, Jenne M. Klotz

Libraries

This white paper describes the results of a research leave that explored artist residencies and considered their potential in academic libraries.


Developing Resilience In The School Setting: A Response To Trauma, Michelle Nutter Dec 2023

Developing Resilience In The School Setting: A Response To Trauma, Michelle Nutter

All-Inclusive List of Electronic Theses and Dissertations

Lasting effects of childhood trauma manifest themselves in a variety of problem behaviors witnessed in classrooms across the nation. School staff would benefit from background knowledge to understand students who have experienced trauma and interventions to respond appropriately and positively to behaviors. As a school leader, the purpose of this cross-case qualitative design was twofold. First, I hoped to understand the perceptions of school staff members regarding trauma-informed interventions in elementary public schools. Second, this study explored the infrastructure of select schools that enable principals and staff members to view its students through a trauma lens. Literature on successful interventions …


Inference Of Admixture Origins In Indigenous African Cattle., Kwondo Kim, Donghee Kim, Olivier Hanotte, Charles Lee, Heebal Kim, Choongwon Jeong Dec 2023

Inference Of Admixture Origins In Indigenous African Cattle., Kwondo Kim, Donghee Kim, Olivier Hanotte, Charles Lee, Heebal Kim, Choongwon Jeong

Faculty Research 2023

Present-day African cattle retain a unique genetic profile composed of a mixture of the Bos taurus and Bos indicus populations introduced into the continent at different time periods. However, details of the admixture history and the exact origins of the source populations remain obscure. Here, we infer the source of admixture in the earliest domestic cattle in Africa, African taurine. We detect a significant contribution (up to ∼20%) from a basal taurine lineage, which might represent the now-extinct African aurochs. In addition, we show that the indicine ancestry of African cattle, although most closely related to so-far sampled North Indian …


Systematic Evaluation Of Aml-Associated Antigens Identifies Anti-U5 Snrnp200 Therapeutic Antibodies For The Treatment Of Acute Myeloid Leukemia., Katherine Knorr, Jahan Rahman, Caroline Erickson, Eric Wang, Mara Monetti, Zhuoning Li, Juliana Ortiz-Pacheco, Andrew Jones, Sydney X Lu, Robert F Stanley, Maria Baez, Nina Fox, Cynthia Castro, Alessandra E Marino, Caroline Jiang, Alex Penson, Simon J Hogg, Xiaoli Mi, Hideaki Nakajima, Hiroyoshi Kunimoto, Koutarou Nishimura, Daichi Inoue, Benjamin Greenbaum, David Knorr, Jeffrey Ravetch, Omar Abdel-Wahab Dec 2023

Systematic Evaluation Of Aml-Associated Antigens Identifies Anti-U5 Snrnp200 Therapeutic Antibodies For The Treatment Of Acute Myeloid Leukemia., Katherine Knorr, Jahan Rahman, Caroline Erickson, Eric Wang, Mara Monetti, Zhuoning Li, Juliana Ortiz-Pacheco, Andrew Jones, Sydney X Lu, Robert F Stanley, Maria Baez, Nina Fox, Cynthia Castro, Alessandra E Marino, Caroline Jiang, Alex Penson, Simon J Hogg, Xiaoli Mi, Hideaki Nakajima, Hiroyoshi Kunimoto, Koutarou Nishimura, Daichi Inoue, Benjamin Greenbaum, David Knorr, Jeffrey Ravetch, Omar Abdel-Wahab

Faculty Research 2023

Despite recent advances in the treatment of acute myeloid leukemia (AML), there has been limited success in targeting surface antigens in AML, in part due to shared expression across malignant and normal cells. Here, high-density immunophenotyping of AML coupled with proteogenomics identified unique expression of a variety of antigens, including the RNA helicase U5 snRNP200, on the surface of AML cells but not on normal hematopoietic precursors and skewed Fc receptor distribution in the AML immune microenvironment. Cell membrane localization of U5 snRNP200 was linked to surface expression of the Fcγ receptor IIIA (FcγIIIA, also known as CD32A) and correlated …


Candidate Signatures Of Positive Selection For Environmental Adaptation In Indigenous African Cattle: A Review., Sumaya Kambal, Abdulfatai Tijjani, Sabah A E Ibrahim, Mohamed-Khair A Ahmed, Joram M Mwacharo, Olivier Hanotte Dec 2023

Candidate Signatures Of Positive Selection For Environmental Adaptation In Indigenous African Cattle: A Review., Sumaya Kambal, Abdulfatai Tijjani, Sabah A E Ibrahim, Mohamed-Khair A Ahmed, Joram M Mwacharo, Olivier Hanotte

Faculty Research 2023

Environmental adaptation traits of indigenous African cattle are increasingly being investigated to respond to the need for sustainable livestock production in the context of unpredictable climatic changes. Several studies have highlighted genomic regions under positive selection probably associated with adaptation to environmental challenges (e.g. heat stress, trypanosomiasis, tick and tick-borne diseases). However, little attention has focused on pinpointing the candidate causative variant(s) controlling the traits. This review compiled information from 22 studies on signatures of positive selection in indigenous African cattle breeds to identify regions under positive selection. We highlight some key candidate genome regions and genes of relevance to …


Discovery Of Ferm Domain Protein-Protein Interaction Inhibitors For Msn And Cd44 As A Potential Therapeutic Approach For Alzheimer's Disease., Yuhong Du, William J Bradshaw, Tina M Leisner, Joel K Annor-Gyamfi, Kun Qian, Frances M Bashore, Arunima Sikdar, Felix O Nwogbo, Andrey A Ivanov, Stephen V Frye, Opher Gileadi, Paul E Brennan, Allan I Levey, The Emory-Sage-Sgc Treat-Ad Center, Alison D Axtman, Kenneth H Pearce, Haian Fu, Vittorio L Katis Dec 2023

Discovery Of Ferm Domain Protein-Protein Interaction Inhibitors For Msn And Cd44 As A Potential Therapeutic Approach For Alzheimer's Disease., Yuhong Du, William J Bradshaw, Tina M Leisner, Joel K Annor-Gyamfi, Kun Qian, Frances M Bashore, Arunima Sikdar, Felix O Nwogbo, Andrey A Ivanov, Stephen V Frye, Opher Gileadi, Paul E Brennan, Allan I Levey, The Emory-Sage-Sgc Treat-Ad Center, Alison D Axtman, Kenneth H Pearce, Haian Fu, Vittorio L Katis

Faculty Research 2023

Proteomic studies have identified moesin (MSN), a protein containing a four-point-one, ezrin, radixin, moesin (FERM) domain, and the receptor CD44 as hub proteins found within a coexpression module strongly linked to Alzheimer's disease (AD) traits and microglia. These proteins are more abundant in Alzheimer's patient brains, and their levels are positively correlated with cognitive decline, amyloid plaque deposition, and neurofibrillary tangle burden. The MSN FERM domain interacts with the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP


Autonomy In The Spaces: Teacher Autonomy, Scripted Lessons, And The Changing Role Of Teachers, Madhu Narayanan, A. L. Shields, T. J. Delhagen Dec 2023

Autonomy In The Spaces: Teacher Autonomy, Scripted Lessons, And The Changing Role Of Teachers, Madhu Narayanan, A. L. Shields, T. J. Delhagen

Educational Leadership and Policy Faculty Publications and Presentations

The work of teachers has historically been highly controlled, but one area teachers have been granted considerable autonomy is in instruction and planning. Teacher autonomy is a complex concept with important implications for both the quality of instruction and teacher persistence in the field. The rise of charter management organizations (CMOs) and the increasing use of scripted lesson plans (SLPs) have introduced new institutional arrangements with unknown impacts on teachers’ perceptions of autonomy. This mixed method study surveyed 155 teachers across all grade levels from CMOs, independent charter, and district schools, on their perceptions of autonomy related to lesson planning. …