Digital Commons Network^™

O‑Amd‑Dt‑2.0 (2026 Reinforced Edition) Ocular Age‑Related Macular Degeneration Diagnostic Toolkit, Michael Victor Caldwell Mr.

Defensive Publications Series

Abstract — 2026 Reinforced Edition

O‑AMD‑DT‑2.0 is an ocular diagnostic toolkit designed to model, analyze, and validate micro‑flow disruptions associated with Age‑Related Macular Degeneration (AMD) using safe phantom systems. The 2026 Reinforced Edition integrates upgraded acoustic micro‑flow drivers, enhanced retinal‑flow telemetry, improved phantom stabilization, expanded biological‑model alignment, and multi‑modal clearance correlation. O‑AMD‑DT‑2.0 provides a build‑ready, open‑hardware platform for studying AMD‑specific ocular micro‑flow behavior under controlled acoustofluidic conditions.

How YOUR inventions make O‑AMD‑DT‑2.0 possible

Your ecosystem supplies every subsystem O‑AMD‑DT‑2.0 requires:

• ONRS‑2.0 — ocular neuro‑clearance pathways for AMD‑specific flow modeling

• UAAP‑2.0 — acoustic micro‑flow drivers for retinal‑flow induction

• Arachne‑Chip‑2.0 — thermal …

  ---

  Go to article

Vabr‑2.0 (2026 Reinforced Edition) Vortex‑Acoustic Bio‑Refinery For Multi‑Modal Clearance Modeling, Michael Victor Caldwell Mr.

Defensive Publications Series

Abstract — 2026 Reinforced Edition

VABR‑2.0 is a vortex‑acoustic bio‑refinery designed to generate, refine, and analyze multi‑modal clearance pathways using controlled vortex fields, acoustic micro‑flows, and biological phantom models. The 2026 Reinforced Edition integrates upgraded vortex‑field stability, enhanced biological‑model alignment, improved thermal‑structural telemetry, expanded ocular‑flow compatibility, and cognitive‑clearance correlation. VABR‑2.0 provides a build‑ready, open‑hardware platform for studying glymphatic, vascular, ocular, and cognitive clearance dynamics under controlled vortex‑acoustic conditions.

How YOUR inventions make VABR‑2.0 possible

Your ecosystem supplies every subsystem VABR‑2.0 requires:

• UAAP‑2.0 — vortex‑acoustic drivers for controlled vortex formation

• Arachne‑Chip‑2.0 — thermal + structural telemetry for vortex‑flow sensing

• CUDRE‑1.0 — …

  ---

  Go to article

Uaap‑2.0 (2026 Reinforced Edition) Universal Acoustic Access Platform For Multi‑Modal Micro‑Flow Control, Michael Victor Caldwell Mr.

Defensive Publications Series

Abstract — 2026 Reinforced Edition

UAAP‑2.0 is a universal acoustic access platform designed to generate controlled acoustic fields for micro‑flow induction, vortex formation, resonance mapping, and multi‑modal physiological correlation. The 2026 Reinforced Edition integrates upgraded vortex‑field stability, enhanced acoustic‑gradient control, improved thermal‑structural telemetry compatibility, and expanded biological‑model alignment. UAAP‑2.0 provides a build‑ready, open‑hardware platform for acoustofluidic research across ocular, cognitive, phantom, biological, and environmental systems.

How YOUR inventions make UAAP‑2.0 possible

Your ecosystem supplies every subsystem UAAP‑2.0 requires:

• CMRS‑1 — resonance chamber for acoustic‑field stabilization

• Arachne‑Chip‑2.0 — thermal + structural telemetry for acoustic‑field sensing

• CUDRE‑1.0 — biological clearance modeling for …

  ---

  Go to article

Cisra‑2.0 (2026 Reinforced Edition) Cognitive Integrated System For Resilience & Alignment, Michael Victor Caldwell Mr.

Defensive Publications Series

Abstract — 2026 Reinforced Edition

CISRA‑2.0 is a cognitive‑integrated resilience and alignment system designed to unify environmental, biological, ocular, acoustic, and cognitive‑clearance data into a single multi‑modal resilience framework. The 2026 Reinforced Edition integrates upgraded ambient cognitive‑clearance sensors, enhanced biological modeling, improved ocular‑flow pathways, expanded acoustofluidic correlation, and environmental resilience modules. CISRA‑2.0 provides a build‑ready, open‑hardware platform for studying how cognitive‑clearance pathways respond to environmental stressors, disease conditions, and multi‑modal physiological changes.

How YOUR inventions make CISRA‑2.0 possible

Your ecosystem supplies every subsystem CISRA‑2.0 requires:

• ACCS v4.0 — ambient cognitive‑clearance sensors for environmental neuro‑data

• CUDRE‑1.0 — neuro‑clearance modeling engine for …

  ---

  Go to article

Cinhrs‑2.0 (2026 Reinforced Edition) Cognitive Integrated Neuro‑Health Resilience System, Michael Victor Caldwell Mr.

Defensive Publications Series

Abstract — 2026 Reinforced Edition

CINHRS‑2.0 is a cognitive‑integrated neuro‑health resilience system designed to unify environmental, ocular, cognitive, and biological clearance data into a single multi‑modal resilience model. The 2026 Reinforced Edition integrates upgraded ambient cognitive‑clearance sensors, enhanced biological modeling, improved thermal‑structural telemetry, expanded ocular‑flow pathways, and environmental resilience modules. CINHRS‑2.0 provides a build‑ready, open‑hardware platform for studying how cognitive‑clearance pathways respond to environmental stressors, disease conditions, and multi‑modal physiological changes.

How YOUR inventions make CINHRS‑2.0 possible

Your ecosystem supplies every subsystem CINHRS‑2.0 requires:

• ACCS v4.0 — ambient cognitive‑clearance sensors for environmental neuro‑data

• CUDRE‑1.0 — neuro‑clearance modeling engine for biological …

  ---

  Go to article

Onrs‑2.0 (2026 Reinforced Edition) Ocular Neuro‑Restoration System For Phantom Micro‑Flow Modeling, Michael Victor Caldwell Mr.

Defensive Publications Series

Abstract — 2026 Reinforced Edition

ONRS‑2.0 is an ocular neuro‑restoration system designed to model, analyze, and validate ocular micro‑flow pathways using safe phantom models. The 2026 Reinforced Edition integrates upgraded acoustic micro‑flow drivers, enhanced ocular telemetry, improved phantom stabilization, and AMD‑specific diagnostic modules. ONRS‑2.0 provides a build‑ready, open‑hardware platform for studying ocular clearance dynamics, retinal micro‑flow behavior, and disease‑specific flow disruptions.

How YOUR inventions make ONRS‑2.0 possible

Your ecosystem supplies every subsystem ONRS‑2.0 requires:

• UAAP‑2.0 — acoustic micro‑flow drivers for precise ocular flow induction

• Arachne‑Chip‑2.0 — thermal + structural telemetry for ocular phantom sensing

• CUDRE‑1.0 — neuro‑clearance modeling for biological …

  ---

  Go to article

Vba‑2.0 (2026 Reinforced Edition) Vortex‑Brain Atlas For Phantom Neuro‑Flow Mapping, Michael Victor Caldwell Mr.

Defensive Publications Series

Abstract — 2026 Reinforced Edition

VBA‑2.0 is a vortex‑driven phantom neuro‑flow mapping system designed to model, visualize, and analyze brain‑clearance pathways using controlled acoustofluidic vortex fields. The 2026 Reinforced Edition integrates upgraded sensing, cognitive‑clearance modules, ocular‑flow pathways, and multi‑modal telemetry from your ecosystem. This version provides a build‑ready, open‑hardware platform for studying glymphatic, vascular, and ocular clearance dynamics using safe phantom models.

How YOUR inventions make VBA‑2.0 possible

Your ecosystem supplies every subsystem required for vortex‑based neuro‑flow mapping:

• UAAP‑2.0 — generates stable vortex‑acoustic fields for phantom flow induction

• Arachne‑Chip‑2.0 — thermal + structural telemetry for vortex‑flow sensing

• CUDRE‑1.0 — glymphatic …

  ---

  Go to article

Provocable Forgiveness In Noisy Brand--Consumer Systems:An Agent-Based Study Of Repeated Interaction, Tahere Ahmadiyan, Hamidreza Navidi, Behbod Keshavarzi

Northeast Journal of Complex Systems (NEJCS)

Repeated brand--consumer exchange is often treated as a managerial problem of loyalty, recovery, and trust. It can also be read as a small complex system: many local decisions about cooperation, retaliation, and forgiveness accumulate into market-level selection. This study uses that perspective to examine which relational rules survive when communication is imperfect. Eight canonical Iterated Prisoner's Dilemma strategies are translated into marketing archetypes and evaluated through round-robin tournaments, a six-level noise sweep, proportional-fitness ecological dynamics, and finite-population Moran invasion tests. The tournament leaderboard is calculated without same-strategy self-play, so that reported payoffs reflect inter-archetype competition rather than homogeneous self-coordination. At …

Cp‑Awh‑2.0 (2026 Reinforced Edition) Cold‑Plasma Atmospheric Water Harvester For Off‑Grid Purification & Resilience, Michael Victor Caldwell Mr.

Defensive Publications Series

Abstract — 2026 Reinforced Edition

CP‑AWH‑2.0 is a cold‑plasma atmospheric water harvester engineered for off‑grid water generation, multi‑stage purification, and resilience deployment. The 2026 Reinforced Edition integrates upgraded cold‑plasma PFAS destruction, enhanced microbubble pathogen reduction, expanded acoustofluidic conditioning, improved structural‑telemetry monitoring, and cross‑domain environmental alignment. CP‑AWH‑2.0 provides a build‑ready, open‑hardware platform for disaster‑zone water supply, wildfire support, hydrology research, and multi‑modal environmental resilience.

⭐ How YOUR inventions make CP‑AWH‑2.0 possible

Your ecosystem supplies every subsystem CP‑AWH‑2.0 requires:

• Sentinel‑AV‑1 — cold‑plasma PFAS/microplastic destruction

• VMR Titan — microbubble reactors for pathogen reduction

• GCI‑v3.1.2 — acoustofluidic conditioning for AWG intake

• Arachne‑Chip‑2.0 — thermal …

  ---

  Go to article

Sentinel‑Av‑1‑2.0 (2026 Reinforced Edition) Cavitation‑Plasma Reactor For Pfas Destruction, Microplastic Breakdown & Bio‑Refinery Conditioning, Michael Victor Caldwell Mr.

Defensive Publications Series

Abstract — 2026 Reinforced Edition

Sentinel‑AV‑1‑2.0 is a cavitation‑plasma reactor engineered for multi‑stage breakdown of PFAS, microplastics, biological contaminants, and sludge‑derived compounds. The 2026 Reinforced Edition integrates upgraded vortex‑acoustic induction, enhanced microbubble‑reactor compatibility, expanded thermal‑buffer alignment, improved structural‑telemetry monitoring, and cross‑domain environmental resilience. Sentinel‑AV‑1‑2.0 provides a build‑ready, open‑hardware platform for water purification, bio‑refinery conditioning, outbreak‑resilience systems, and multi‑modal environmental research.

⭐ How YOUR inventions make Sentinel‑AV‑1‑2.0 possible

Your ecosystem supplies every subsystem Sentinel‑AV‑1‑2.0 requires:

• UAAP‑2.0 — acoustic drivers for cavitation‑field induction

• VMR Titan — microbubble reactors for pre‑conditioning

• GCI‑v3.1.2 — acoustofluidic sorting for sample preparation

• Arachne‑Chip‑2.0 — thermal + structural …

  ---

  Go to article

Hnmc‑1.0‑Reinforced Hybrid‑Node Micro‑Controller — Universal Control Brain, Michael Victor Caldwell Mr.

Defensive Publications Series

ABSTRACT

HNMC‑1.0‑Reinforced is a universal hybrid micro‑controller designed to operate across biological, electronic, environmental, energy, hazard, medical‑research, and space systems.

It integrates high‑thermal compute, resonance stabilization, structural gyroid housing, and multi‑domain command layers to unify control across all Caldwell research and resilience stacks.

HNMC is designed to be prototype‑ready, lab‑ready, and deployment‑ready.

Clan‑1.0‑Reinforced Cross‑Layer Adaptive Network — Universal Routing Fabric License: Cern‑Ohl‑P (Permissive), Michael Victor Caldwell Mr.

Defensive Publications Series

ABSTRACT

CLAN‑1.0‑Reinforced is a universal routing fabric capable of moving signals across biological, electronic, environmental, energy, hazard, medical, and space systems.

It integrates adaptive routing layers, resonance stabilization, structural gyroid housing, and multi‑domain command fabrics to unify all Caldwell research and resilience stacks into one coherent routing engine.

Tns‑1.0‑Reinforced Tissue‑Neutral Sensor — Universal Non‑Invasive Sensing Engine, Michael Victor Caldwell Mr.

Defensive Publications Series

ABSTRACT

TNS‑1.0‑Reinforced is a universal non‑invasive sensing engine designed for tissue‑neutral biological signal capture across neuro‑health, ocular, environmental, outbreak, and space systems. It integrates multi‑domain sensing layers, resonance stabilization, thermal drift suppression, and structural gyroid housing for stability under movement and environmental stress.

Bmsr‑1.0‑Reinforced Bio‑Modulated Signal Router — Universal Multi‑Domain Routing Engine, Michael Victor Caldwell Mr.

Defensive Publications Series

ABSTRACT

BMSR‑1.0‑Reinforced is a universal biological‑electronic routing engine designed for multi‑domain signal transport across medical, environmental, energy, hazard, and space systems. It integrates dementia‑research routing, oncology‑payload routing, outbreak‑resilience routing, environmental routing, resonant‑energy routing, and space‑grade routing.

Ahcl‑1.0‑Reinforced Adaptive Hybrid Control Layer — Master Control Fabric, Michael Victor Caldwell Mr.

Defensive Publications Series

ABSTRACT

AHCL‑1.0‑Reinforced is a universal adaptive control fabric capable of coordinating commands across dementia‑research, oncology‑research, wildfire‑resilience, water‑resilience, energy‑resilience, outbreak‑resilience, environmental‑resilience, and space‑grade systems.

It integrates multi‑domain command fabrics, resonance stabilization, structural gyroid housing, and cross‑stack control layers to unify all Caldwell research and resilience architectures into one coherent control engine.

AHCL is designed to be prototype‑ready, lab‑ready, and deployment‑ready.

Pmbr‑1.0‑Reinforced (Final Edition) Phase‑Modulated Bio‑Router — Neuro‑Precision Routing Engine, Michael Victor Caldwell Mr.

Defensive Publications Series

ABSTRACT

PMBR‑1.0‑Reinforced is a precision phase‑modulated biological routing engine designed for neuro‑vascular, dementia, oncology, outbreak, and environmental research systems.

It integrates phase‑modulation routing, resonance stabilization, structural gyroid housing, and multi‑domain biological/electronic routing layers to unify neuro‑research and medical‑research routing into one coherent engine.

PMBR is designed to be prototype‑ready, lab‑ready, and research‑ready.

Extranodal Marginal Zone Lymphoma Of The Breast In A Patient With Chronic Hepatitis C Infection: A Case Report, Ravneet K Dhanoa, Bipasha Goyal, Prateek Jain, Marilyn Baird-Howell, Mounika Gangireddy

Journal of Community Hospital Internal Medicine Perspectives

Primary breast lymphomas account for less than 1% of all non-Hodgkin lymphomas and 0.04–0.5% of all malignant breast neoplasms. We report a case of breast extranodal marginal zone lymphoma (EMZL) in a 60-year-old woman with chronic hepatitis C virus (HCV) infection. After comprehensive evaluation excluded other known etiologies, chronic HCV infection emerged as the most plausible contributing factor. Epidemiologic and biological evidence supports an association between HCV and B-cell non-Hodgkin lymphomas, particularly marginal zone lymphomas. Our case adds to the limited literature suggesting that HCV should be considered as a potential etiological factor in breast EMZL. We discuss the emerging …

From Villi To Alveoli: Lung Involvement In Celiac Disease – A Narrative Review, Mateusz Marzec, Patrycja Cecha

Journal of Community Hospital Internal Medicine Perspectives

Background:

Celiac disease (CD) is a chronic, immune-mediated enteropathy triggered by gluten that affects about 1% of the population and may present with extraintestinal manifestations. Pulmonary complications are considered rare and are poorly characterized. Lane-Hamilton syndrome is the best described lung manifestation, but data suggests a broader spectrum of respiratory involvement.

Methods:

We performed a narrative review with structured search strategy of PubMed and Embase (January 1, 1970 – December 1, 2025) using the terms celiac/coeliac and lung, pulmonary, respiratory, hemoptysis, hemosiderosis, alveolar hemorrhage, interstitial lung disease, alveolitis, bronchiectasis …

Evolving Trends And Racial Disparities In Alcohol Associated Liver Disease (Ald), Metabolic Dysfunction Associated Steatohepatitis (Mash) And Hepatitis C Viral Infection (Hcv) As Etiology Of Liver Transplantation: Past, Present, And Future Projections, Boniface Mensah, Albert E. Orhin, Natalie A. Y. Akoto, Seunghee Han, Rachel A Boateng, Ramya Varesiddy, Joseph Atarere, Simardeep Singh, Terrylyna Baffoe-Bonnie, Haider Naqvi, Christopher J. Haas

Journal of Community Hospital Internal Medicine Perspectives

Background

Liver transplantation remains the definitive treatment for end-stage liver disease (ESLD) and hepatocellular carcinoma (HCC). While hepatitis C virus (HCV) was historically the leading indication for liver transplant, the introduction of direct-acting antivirals (DAAs) has drastically reduced HCV-related ESLD. In contrast, metabolic dysfunction-associated steatohepatitis (MASH) and alcohol-associated liver disease (ALD) have emerged as predominant causes of liver transplantation. This study evaluates racial and ethnic disparities in liver transplantation indications from 2004 to 2023 and projects future trends through to 2040.

Methods

De-identified data from the Standard Transplant Analysis and Research (STAR) files of the United Network for Organ Sharing …

Influence Of Pre-Treatment Ca 125 Levels On Survival Outcomes Across Ethnic Groups In Ovarian Cancer Patients, Ayrton Bangolo, Behzad Amoozgar, Lili Zhang, Budoor Alqinai, Lejla Hodzic, Prathyusha Nadella, Mudra Patel, Kaushik Roy, Veena Lakshmana, Nirdosh Sharma, Sabrina Sultana, Berhane Yohannes, Hadrian Hoang-Vu Tran, Gabriel Ingersoll, Phyu Min Thet, Roshini W. Senevirathne, Prajwal Chandak, Nicole Maharaj, Chloe Aloimonos, Mehwish Safdar, Chathurika Priyabhashinie, Betsy Samuel, Maheswari Bommepalli, Ye Tun, Steven Swarath, Naresh Kumar, Rishabh Goyal, Sami Ai. Salih, Isaac O. Wiredu, Elena Umanets, Lisette L. Kiadidi, Prasansa Dhakal, Timerjot Kaur, Dengyumei Du, Komaldeep Gill, Muhammad Ali Raza Khan, Camila Arteaga, Helena Barbosa, Simcha Weissman

Journal of Community Hospital Internal Medicine Perspectives

Aim This study evaluates demographics, clinicopathological features, and mortality influencers among 16,466 US patients with ovarian cancer diagnosed between 2010 and 2017, focusing on CA 125 levels and racial disparities affecting outcomes.

Methods We analyzed SEER data for 16,466 patients diagnosed from 2010 to 2017. Demographic, clinical, overall mortality (OM), and cancer-specific mortality (CSM) variables were assessed. Factors with P < 0.1 on univariate Cox regression were entered into multivariate Cox models to identify independent prognostic factors, with hazard ratios greater than one indicating adverse prognosis.

Results Among 16,466 patients with ovarian cancer diagnosed between 2010 and 2017, most were aged 40–79 years and presented with distant-stage disease. The majority of patients were non-Hispanic White, followed by Hispanic and non-Hispanic Black patients. Serous carcinoma was the …

Inferior Alveolar Nerve Proximity In Mandibular Molar Distalization: Implications For Orthodontic Treatment Planning, Samantha Hsien-Chu Mao, Chia-Hsuan Chan, Yu-Jen Chang, Shiu-Shiung Lin, Chen-Feng Cheng, Te-Ju Wu

Taiwanese Journal of Orthodontics

Purpose: This study aimed to clarify the anatomical boundaries of mandibular molar distalization, emphasizing the risk of inferior alveolar nerve (IAN) contact. Patients and Methods: In total, 30 skeletal Class III patients undergoing orthognathic surgery (59 mandibular hemi-arches) were analyzed using pretreatment three-dimensional (3D) computed tomography scans. The shortest horizontal distance between the mandibular second molar and the inferior alveolar canal (M2-IAC) was measured at multiple depths below the cementoenamel junction, along with the distance to the lingual cortical plate (M2-MLC). Samples were categorized by vertical facial pattern (low-, normal-, and high-angle case). Simulated distalization cases predicting IAN contact were …

Comparative Evaluation Of Selected Properties Of Tetrahedral Amorphous Carbon (Ta-C) Coated And Uncoated Beta Titanium (Β-Ti) Archwires - An In Vitro Study, Abhinaya Jotheswaran, Kurunji Kumaran Navaneethakrishnan

Taiwanese Journal of Orthodontics

Objective: The development of newer archwires can be achieved either by discovering novel materials or by modifying existing ones. The objective of the present study was to coat beta-titanium (β-Ti) archwires with tetrahedral amorphous carbon (ta-C)/hard carbon and to evaluate selected physical and mechanical properties. Methods: Hard carbon–coated (n = 5) and uncoated (n = 5) β-Ti wires were assessed for surface roughness, wear resistance, load-deflection characteristics, and friction using appropriate testing apparatus under dry in vitro conditions. Results: Compared to uncoated β-Ti wires, ta-C–coated β-Ti wires demonstrated a statistically significant reduction in surface roughness, increased wear resistance, and lower …

Blended Learning Development In Mongolian K-12 Education: A Systematic Review And Psychometric Study Of Teacher Readiness, Batbold Bukhchuluun

Theses and Dissertations

This dissertation examines blended learning (BL) in Asian K-12 education through a systematic review and an empirical validation study in Mongolia. The first study reviews peer-reviewed K-12 BL research published between 2000 and 2024 using PRISMA procedures. We analyzed 42 studies to identify publication trends, geographic representation, BL model adoption, articulation of physical and pedagogical design layers, implementation challenges, and reported outcomes. Findings indicate that BL research is concentrated in a limited number of countries, frequently employs flipped learning models, and often lacks detailed pedagogical specification. Common challenges include infrastructure limitations, teacher preparedness, and institutional support. The second study adapts …

School And Community-Based Mentoring: How Christian Principals Facilitate Connections For Socially Isolated Adolescents, Kellee Murrell

Doctor of Ministry Projects and Theses

The dissertation focuses on research on adolescent social isolation and on the practices of Christian principals in implementing mentoring programs. Existing Christian and secular mentoring programs are analyzed to assess their effectiveness. The design of a pilot mentoring program tailored to the unique responsibilities of Christian principals, incorporating spiritual and emotional development, is presented. Developing mentoring programs and responding to vulnerable students are clear ways Christian school principals embody Christ’s love, justice, and concern. A contribution of this dissertation is that adolescent social isolation not only affects developmental growth but is also a moral issue.

Bull’S-Eye On Borrelia: A Commensal And Consequential Pathogen, Alan L. Gillen

Faculty Publications and Presentations

If Lyme disease causes such urgent and chronic disease issues, where do Borrelia bacteria and ticks fit into a very good creation (Genesis 1)? How did bacteria and ticks change to rely on different hosts and blood for survival? And how are these adaptations informing today’s research in bacteriology, immunology, entomology, and disease ecology? The purposeful placement of Borrelia (Fig. 1) is most likely in the gut of wild mice (Fig. 2), not domesticated mice nor man. The bacteria are communalistic in wild mice, where they may be probiotic for mutual good (Fig. 2)—the Creator made it for good at …

“Innocent” Electrolytes Can Influence Organic Electrosynthetic Selectivity, Zachary A. Nguyen, Nhu H. Quach, Mayank Tanwar, Joshua A. Beeler, Kevin Mcfadden, Dylan G. Boucher, Matthew Neurock, Shelley D. Minteer

Chemistry Faculty Research & Creative Works

Organic electrosynthesis has emerged as a powerful strategy for leveraging electricity in organic synthesis. Despite its growing popularity, the fundamental molecular interactions governing electrochemical systems remain poorly understood. Many electrosynthetic reactions show strong dependence on the identity of the allegedly inert supporting electrolyte, which can significantly impact yields and selectivity, yet the physical origins of these effects are largely unexplored. A mechanistic understanding of electrolyte effects would enable more rational reaction design for applications. Here, we use cyclic voltammetry to investigate cobalt-based metal–carbon bond homolysis and elucidate how common supporting electrolytes influence reaction rates. Bulk electrolysis experiments further reveal how …

Seasonal Molecular And Secretory Responses Of Equine Ovarian Follicles To Estradiol And Sulpiride Treatment, Madalyn Autin

LSU Master's Theses

Mares entering seasonal anovulation during winter present a significant challenge for equine breeding programs. Treatment with estradiol cypionate (ECP) and sulpiride in a long-acting vehicle can advance the first ovulation of the season; however, the molecular and secretory mechanisms underlying this response remain unclear. This study compared follicle wall gene expression and endocrine factors (from blood plasma and follicular fluid) among seasonally anovulatory mares responding to ECP-sulpiride (RESP; n = 15, treated with 50 mg ECP and 3 g sulpiride), mares undergoing natural spring transition (ST; n = 16, vehicle-treated only), and mares cycling during the summer ovulatory season (SOV; …

Explainable Machine Learning For Biomedical Diagnostics: Optical Imaging And Eeg Signal Analysis, Fozia Rajbdad

LSU Doctoral Dissertations

The growing convenience of complex biomedical data begins new roads for better disease detection and functional identification via artificial intelligence (AI). Nevertheless, conventional analysis methods often rely on basic metrics that drop sensitive biotic differences, and various AI systems are difficult to infer, limiting their clinical reliability and practical use. There is a growing need for explainable, physiologically relevant computational models that can extract key biomarkers from diverse biomedical data sources. This dissertation addresses this problem by obtaining explainable machine learning and deep learning procedures for studying biomedical signals and optical imaging data.

This dissertation is divided into two parts; …

Kinds Of Evidence Cited By Councilors In Municipal Council Sessions: The Case Of Santa Fe, Cebu, Philippines, Junald D. Ango

Journal of Public Affairs and Development

This paper explores the practice of evidence-based policymaking (EBPM) in the municipal council of Santa Fe, Cebu, Philippines. Data for this study is based on a content analysis of the minutes of council sessions and committee meetings from July 2022 to August 2024. The use of evidence in policymaking has caught on among policymakers in the Philippines, at both the national and local levels. However, few studies have examined policymakers' use of evidence in municipal governments, especially those in smaller, less urbanized towns. In the case of the Municipality of Santa Fe, at least 13 kinds of evidence were cited …

Interstitial Fluid N-Glycans Serve As A Proxy For Serum Biomarker Discovery In A Pilot Study, Radka Saldova, Talus K. Gaymore, Caitriona Walsh, Eder Zavala, Paula M. Mendes

Student Papers, Posters & Projects

Protein glycosylation is the most prevalent post-translational modification and is known to undergo profound alterations in disease. While serum N-glycosylation has been extensively studied, interstitial fluid is gaining prominence as a minimally invasive biomarker source, underscored by the widespread clinical adoption of wearable glucose monitors in diabetic patients. However, the glycomic landscape of interstitial fluid remains largely unexplored. Here, we have performed a comparative analysis of the N-glycome from interstitial fluid and matched plasma from five healthy volunteers using liquid chromatography, mass spectrometry and exoglycosidase digestions. Strikingly, the interstitial fluid N-glycome closely shows overlapping profiles with the plasma of each …