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2023

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Novel Index To Predict Mortality And Inform Malnutrition?, Jacob T. Mey Feb 2023

Novel Index To Predict Mortality And Inform Malnutrition?, Jacob T. Mey

Division of Basic Science Faculty Publications

No abstract provided.

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Wetland Occupancy By Duck Broods In Cropland-Dominated Landscapes Of The United States Prairie Pothole Region, Blake J. Mitchell, Catrina V. Terry, Kevin M. Ringelman, Kaylan M. Kemink, Michael J. Anteau, Adam K. Janke Feb 2023

Wetland Occupancy By Duck Broods In Cropland-Dominated Landscapes Of The United States Prairie Pothole Region, Blake J. Mitchell, Catrina V. Terry, Kevin M. Ringelman, Kaylan M. Kemink, Michael J. Anteau, Adam K. Janke

Faculty Publications

The Prairie Pothole Region (PPR) is globally important for breeding waterfowl but has been altered via wetland drainage and grassland conversion to accommodate agricultural land use. Thus, understanding the ecology of waterfowl in these highly modified landscapes is essential for their conservation. Brood occurrence is the cumulative outcome of key life-history events including pair formation and territory establishment, nest success, and early brood survival. We applied new technological advances in brood surveying methods to understand brood use of wetlands and how land use and wetland-specific factors influenced brood use of 413 wetlands in crop-dominated landscapes in the PPR of Iowa, …

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Glucagon-Like Peptide-1/Glucagon Receptor Agonism Associates With Reduced Metabolic Adaptation And Higher Fat Oxidation: A Randomized Trial, Karen D. Corbin, Elvis A. Carnero, Timothy D. Allerton, Joachim Tillner, Christopher P. Bock, Pierre Philippe Luyet, Britta Göbel, Kevin D. Hall, Stephanie A. Parsons, Eric Ravussin, Steven R. Smith Feb 2023

Glucagon-Like Peptide-1/Glucagon Receptor Agonism Associates With Reduced Metabolic Adaptation And Higher Fat Oxidation: A Randomized Trial, Karen D. Corbin, Elvis A. Carnero, Timothy D. Allerton, Joachim Tillner, Christopher P. Bock, Pierre Philippe Luyet, Britta Göbel, Kevin D. Hall, Stephanie A. Parsons, Eric Ravussin, Steven R. Smith

Clinical Research Faculty Publications

Objective: This study tested the hypothesis that treatment with the glucagon-like peptide-1/glucagon receptor agonist SAR425899 would lead to a smaller decrease in sleeping metabolic rate (SMR; kilocalories/day) than expected from the loss of lean and fat mass (metabolic adaptation). Methods: This Phase 1b, double-blind, randomized, placebo-controlled study was conducted at two centers in inpatient metabolic wards. Thirty-five healthy males and females with overweight and obesity (age = 36.5 ± 7.1 years) were randomized to a calorie-reduced diet (−1000 kcal/d) and escalating doses (0.06-0.2 mg/d) of SAR425899 (n = 17) or placebo (n = 18) for 19 days. SMR was measured …

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Early Time-Restricted Eating Affects Weight, Metabolic Health, Mood, And Sleep In Adherent Completers: A Secondary Analysis, Felicia L. Steger, Humaira Jamshed, David R. Bryan, Joshua S. Richman, Amy H. Warriner, Cody J. Hanick, Corby K. Martin, Sarah Jeanne Salvy, Courtney M. Peterson Feb 2023

Early Time-Restricted Eating Affects Weight, Metabolic Health, Mood, And Sleep In Adherent Completers: A Secondary Analysis, Felicia L. Steger, Humaira Jamshed, David R. Bryan, Joshua S. Richman, Amy H. Warriner, Cody J. Hanick, Corby K. Martin, Sarah Jeanne Salvy, Courtney M. Peterson

Clinical Research Faculty Publications

Objective: Data are mixed on whether intermittent fasting improves weight loss and cardiometabolic health. Here, the effects of time-restricted eating (TRE) in participants who consistently adhered ≥5 d/wk every week were analyzed. Methods: Ninety patients aged 25 to 75 years old with obesity were randomized to early TRE (eTRE; 8-hour eating window from 07:00 to 15:00) or a control schedule (≥12-hour window) for 14 weeks. A per-protocol analysis of weight loss, body composition, cardiometabolic health, and other end points was performed. Results: Participants who adhered to eTRE ≥5 d/wk every week had greater improvements in body weight (−3.7 ± 1.2 …

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Impact Of Early Time-Restricted Eating On Diet Quality, Meal Frequency, Appetite, And Eating Behaviors: A Randomized Trial, Felicia L. Steger, Humaira Jamshed, Corby K. Martin, Joshua S. Richman, David R. Bryan, Cody J. Hanick, Sarah Jeanne Salvy, Amy H. Warriner, Courtney M. Peterson Feb 2023

Impact Of Early Time-Restricted Eating On Diet Quality, Meal Frequency, Appetite, And Eating Behaviors: A Randomized Trial, Felicia L. Steger, Humaira Jamshed, Corby K. Martin, Joshua S. Richman, David R. Bryan, Cody J. Hanick, Sarah Jeanne Salvy, Amy H. Warriner, Courtney M. Peterson

Clinical Research Faculty Publications

Objective: Time-restricted eating (TRE) can reduce body weight, but it is unclear how it influences dietary patterns and behavior. Therefore, this study assessed the effects of TRE on diet quality, appetite, and several eating behaviors. Methods: Adults with obesity were randomized to early TRE plus energy restriction (eTRE + ER; 8-hour eating window from 7:00 a.m. to 3:00 p.m.) or a control eating schedule plus energy restriction (CON + ER; ≥12-hour window) for 14 weeks. Food intake was assessed via the Remote Food Photography Method, while eating patterns, appetite, and eating behaviors were assessed via questionnaires. Results: A total of …

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Framework Of The Alu Subfamily Evolution In The Platyrrhine Three-Family Clade Of Cebidae, Callithrichidae, And Aotidae, Jessica M. Storer, Jerilyn A. Walker, Jasmine N. Baker, Shifat Hossain, Christian Roos, Travis J. Wheeler, Mark A. Batzer Feb 2023

Framework Of The Alu Subfamily Evolution In The Platyrrhine Three-Family Clade Of Cebidae, Callithrichidae, And Aotidae, Jessica M. Storer, Jerilyn A. Walker, Jasmine N. Baker, Shifat Hossain, Christian Roos, Travis J. Wheeler, Mark A. Batzer

Faculty Publications

The history of Alu retroposons has been choreographed by the systematic accumulation of inherited diagnostic nucleotide substitutions to form discrete subfamilies, each having a distinct nucleotide consensus sequence. The oldest subfamily, AluJ, gave rise to AluS after the split between Strepsirrhini and what would become Catarrhini and Platyrrhini. The AluS lineage gave rise to AluY in catarrhines and to AluTa in platyrrhines. Platyrrhine Alu subfamilies Ta7, Ta10, and Ta15 were assigned names based on a standardized nomenclature. However, with the subsequent intensification of whole genome sequencing (WGS), large scale analyses to characterize Alu subfamilies using the program COSEG identified entire …

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The Role Of Nutrition In Mitigating The Effects Of Covid-19 From Infection Through Pasc, Jacob T. Mey, John P. Kirwan, Christopher L. Axelrod Feb 2023

The Role Of Nutrition In Mitigating The Effects Of Covid-19 From Infection Through Pasc, Jacob T. Mey, John P. Kirwan, Christopher L. Axelrod

Division of Basic Science Faculty Publications

The expansive and rapid spread of the SARS-CoV-2 virus has resulted in a global pandemic of COVID-19 infection and disease. Though initially perceived to be acute in nature, many patients report persistent and recurrent symptoms beyond the infectious period. Emerging as a new epidemic, “long-COVID”, or post-acute sequelae of coronavirus disease (PASC), has substantially altered the lives of millions of people globally. Symptoms of both COVID-19 and PASC are individual, but share commonality to established respiratory viruses, which include but are not limited to chest pain, shortness of breath, fatigue, along with adverse metabolic and pulmonary health effects. Nutrition plays …

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Identification Of Differential-Expressed Genes In Banana-Biostimulant Interaction Using Suppression Subtractive Hybridization, Tatiana Chavez-Navarrete, Luis Sanchez-Timm, Ricardo Pacheco-Coello, Niranjan Baisakh, Efrén Santos-Ordóñez Feb 2023

Identification Of Differential-Expressed Genes In Banana-Biostimulant Interaction Using Suppression Subtractive Hybridization, Tatiana Chavez-Navarrete, Luis Sanchez-Timm, Ricardo Pacheco-Coello, Niranjan Baisakh, Efrén Santos-Ordóñez

Faculty Publications

The use of environmental-friendly agricultural inputs to increase yield in crops could reduce environmental contamination and alleviate (a)biotic stress. In this study, we applied a foliar liquid biostimulant to banana plants, which was developed from the anaerobic fermentation of microorganisms with organic remains (manure and plant waste) and minerals to use as environmental-friendly product. To determine the effect of this biostimulant in the plants, a Suppression Subtractive Hybridization (SSH) library was developed from banana leaves in greenhouse conditions. Furthermore, salicylic and jasmonic pathways activation was evaluated by gene expression analysis. First, the application of the biostimulant to banana leaves increased …

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Causes And Characteristics Of Electrical Resistivity Variability In Shallow (<4 M) Soils In Taylor Valley, East Antarctica, W. S. Gutterman, P. T. Doran, R. A. Virginia, J. E. Barrett, K. F. Myers, S. M. Tulaczyk, N. T. Foley, J. A. Mikucki, H. A. Dugan, D. J. Grombacher, T. S. Bording, E. Auken Feb 2023

Causes And Characteristics Of Electrical Resistivity Variability In Shallow (<4 M) Soils In Taylor Valley, East Antarctica, W. S. Gutterman, P. T. Doran, R. A. Virginia, J. E. Barrett, K. F. Myers, S. M. Tulaczyk, N. T. Foley, J. A. Mikucki, H. A. Dugan, D. J. Grombacher, T. S. Bording, E. Auken

Faculty Publications

Airborne electromagnetic surveys collected in December 2011 and November 2018 and three soil sampling transects were used to analyze the spatial heterogeneity of shallow (< 4 m) soil properties in lower Taylor Valley (TV), East Antarctica. Soil resistivities from 2011 to 2018 ranged from ∼33 Ωm to ∼3,500 Ωm with 200 Ωm assigned as an upper boundary for brine-saturated sediments. Elevations below ∼50 m above sea level (masl) typically exhibit the lowest resistivities with resistivity increasing at high elevations on steeper slopes. Soil water content was empirically estimated from electrical resistivities using Archie's Law and range from ∼< 1% to ∼68% by volume. An increase in silt- and clay-sized particles at low elevations increases soil porosity but decreases hydraulic conductivity, promoting greater residence times of soil water at low elevations near Lake Fryxell. Soil resistivity variability between 2011 and 2018 shows soils at different stages of soil freeze-thaw cycles, which are caused predominantly by solar warming of soils as opposed to air temperature. This study furthers the understanding of the hydrogeologic structure of the shallow subsurface in TV and identifies locations of soils that are potentially prone to greater rates of thaw and resulting ecosystem homogenization of soil properties from projected increases in hydrological connectivity across the region over the coming decades.

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Appraisal Of Clinical Care Practices For Child Obesity Treatment. Part Ii: Comorbidities, Asheley C. Skinner, Amanda E. Staiano, Sarah C. Armstrong, Shari L. Barkin, Sandra G. Hassink, Jennifer E. Moore, Jennifer S. Savage, Helene Vilme, Ashley E. Weedn, Janice Liebhart, Jeanne Lindros, Eileen M. Reilly Feb 2023

Appraisal Of Clinical Care Practices For Child Obesity Treatment. Part Ii: Comorbidities, Asheley C. Skinner, Amanda E. Staiano, Sarah C. Armstrong, Shari L. Barkin, Sandra G. Hassink, Jennifer E. Moore, Jennifer S. Savage, Helene Vilme, Ashley E. Weedn, Janice Liebhart, Jeanne Lindros, Eileen M. Reilly

Population and Public Health Science Faculty Publications

The objective of this technical report is to provide clinicians with actionable evidence-based information upon which to make treatment decisions. In addition, this report will provide an evidence base on which to inform clinical practice guidelines for the management and treatment of overweight and obesity in children and adolescents. To this end, the goal of this report was to identify all relevant studies to answer 2 overarching key questions: (KQ1) “What are effective clinically based treatments for obesity?” and (KQ2) “What is the risk of comorbidities among children with obesity?” See Appendix 1 for the conceptual framework and a priori …

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Envirome-Wide Associations Enhance Multi-Year Genome-Based Prediction Of Historical Wheat Breeding Data, Germano Costa-Neto, Leonardo Crespo-Herrera, Nick Fradgley, Keith Gardner, Alison R. Bentley, Susanne Dreisigacker, Roberto Fritsche-Neto, Osval A. Montesinos-López, Jose Crossa Feb 2023

Envirome-Wide Associations Enhance Multi-Year Genome-Based Prediction Of Historical Wheat Breeding Data, Germano Costa-Neto, Leonardo Crespo-Herrera, Nick Fradgley, Keith Gardner, Alison R. Bentley, Susanne Dreisigacker, Roberto Fritsche-Neto, Osval A. Montesinos-López, Jose Crossa

Faculty Publications

Linking high-throughput environmental data (enviromics) to genomic prediction (GP) is a cost-effective strategy for increasing selection intensity under genotype-by-environment interactions (G × E). This study developed a data-driven approach based on Environment–Phenotype Association (EPA) aimed at recycling important G × E information from historical breeding data. EPA was developed in two applications: (1) scanning a secondary source of genetic variation, weighted from the shared reaction-norms of past-evaluated genotypes and (2) pinpointing weights of the similarity among trial-sites (locations), given the historical impact of each envirotyping data variable for a given site. These results were then used as a dimensionality reduction …

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Discovery Of Novel Bioactive Tanshinones And Carnosol Analogues Against Breast Cancer, Miguel A. González-Cardenete, Natalia González-Zapata, Lucinda Boyd, Fatima Rivas Feb 2023

Discovery Of Novel Bioactive Tanshinones And Carnosol Analogues Against Breast Cancer, Miguel A. González-Cardenete, Natalia González-Zapata, Lucinda Boyd, Fatima Rivas

Faculty Publications

The abietane diterpenoids ferruginol (1), tanshinone IIA (3), and carnosol (4) are well-known for their interesting pharmacological properties, including antitumor, similar to other natural and semisynthetic abietanes. In this study, a pair of semisynthetic C18-functionalized analogues of 3 and 4 were prepared from the commercially available (+)-dehydroabietylamine or readily obtained methyl dehydroabietate. Semisynthetic ferruginol (1) and some selected analogues, together with the synthesized analogues, were tested in vitro for the inhibition of proliferation in four breast cancer cell lines, SUM149, MDA-MB231, T47D, and MCF07. As a result, several tested abietane analogues decreased cell proliferation and enhanced cell death, with IC50 …

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Sustainability Hub Newsletter - February 2023, Jacqueline Jergensen, Neyda Gilman, Jennifer Embree Feb 2023

Sustainability Hub Newsletter - February 2023, Jacqueline Jergensen, Neyda Gilman, Jennifer Embree

Library Sustainability Resources

This issue of the Sustainability Hub Newsletter shares tips on what seeds you can start planting indoors and inspiration on which plants to grow this season! Keep reading to learn about planting by the moon, new resources, and important announcements!

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Cultural Factors Associated With Human Trafficking Of Girls And Women In Northern Tanzania: The Case Of Arusha Region, Rehema John Magesa Feb 2023

Cultural Factors Associated With Human Trafficking Of Girls And Women In Northern Tanzania: The Case Of Arusha Region, Rehema John Magesa

Dignity: A Journal of Analysis of Exploitation and Violence

Human trafficking is persistent in many regions of Tanzania despite different efforts to reduce the practice by the Government and other stakeholders. Girls and young women are more affected by this practice in violation of their human rights than men and boys. This study explored the cultural factors attributing to the trafficking of girls and women in Northern Tanzania. The study involved 400 girls and young women for a quantitative and qualitative study on cultural determinants of human trafficking. The study found the following cultural practices pushed girls and women towards situations in which they could be trafficked: female genital …

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A Theoretical Framework For The Ecological Role Of Three-Dimensional Structural Diversity, Elizabeth A. Larue, Robert T. Fahey, Brandon C. Alveshere, Jeff W. Atkins, Parth Bhatt, Brian Buma, Anping Chen, Stella Cousins, Jessica M. Elliott, Andrew J. Elmore, Christopher R. Hakkenberg, Brady S. Hardiman, Jeremy S. Johnson, Daniel M. Kashian, Anil Koirala, Monica Papeş, Jamille B. St Hilaire, Thilina D. Surasinghe, Jenny Zambrano, Lu Zhai, Songlin Fei Feb 2023

A Theoretical Framework For The Ecological Role Of Three-Dimensional Structural Diversity, Elizabeth A. Larue, Robert T. Fahey, Brandon C. Alveshere, Jeff W. Atkins, Parth Bhatt, Brian Buma, Anping Chen, Stella Cousins, Jessica M. Elliott, Andrew J. Elmore, Christopher R. Hakkenberg, Brady S. Hardiman, Jeremy S. Johnson, Daniel M. Kashian, Anil Koirala, Monica Papeş, Jamille B. St Hilaire, Thilina D. Surasinghe, Jenny Zambrano, Lu Zhai, Songlin Fei

Michigan Tech Publications, Part 1

The three-dimensional (3D) physical aspects of ecosystems are intrinsically linked to ecological processes. Here, we describe structural diversity as the volumetric capacity, physical arrangement, and identity/traits of biotic components in an ecosystem. Despite being recognized in earlier ecological studies, structural diversity has been largely overlooked due to an absence of not only a theoretical foundation but also effective measurement tools. We present a framework for conceptualizing structural diversity and suggest how to facilitate its broader incorporation into ecological theory and practice. We also discuss how the interplay of genetic and environmental factors underpin structural diversity, allowing for a potentially unique …

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Inner Work Community: Shadow Work As Spiritual Formation, Michael Simmons Feb 2023

Inner Work Community: Shadow Work As Spiritual Formation, Michael Simmons

Doctor of Leadership

The NPO statement surrounding this doctoral project is that A theological, practical, and community-centered framework for shadow work is disconnected from Christian spiritual formation. This doctoral project is the culmination of a three-fold process: discovering the need for shadow work in the context of spiritual formation, designing multi-faceted virtually-based opportunities to address this need among individuals and groups, and delivering those opportunities via online courses, one-on-one shadow work, and digital content such as essays, articles, and podcasts. My vocational context is my unofficial organization, and MVP, Inner Work Community, which provides these opportunities. Inner Work Community is extended through partnerships …

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Optimal Stomatal Theory Predicts Co2 Responses Of Stomatal Conductance In Both Gymnosperm And Angiosperm Trees, Anna Gardner, Mingkai Jiang, David S. Ellsworth, A. Robert Mackenzie, Jeremy Pritchard, Martin Karl Friedrich Bader, Craig V.M. Barton, Carl Bernacchi, Carlo Calfapietra, Kristine Y. Crous, Mirindi Eric Dusenge, Teresa E. Gimeno, Marianne Hall, Shubhangi Lamba, Sebastian Leuzinger, Johan Uddling, Jeffrey Warren, Göran Wallin, Belinda E. Medlyn Feb 2023

Optimal Stomatal Theory Predicts Co2 Responses Of Stomatal Conductance In Both Gymnosperm And Angiosperm Trees, Anna Gardner, Mingkai Jiang, David S. Ellsworth, A. Robert Mackenzie, Jeremy Pritchard, Martin Karl Friedrich Bader, Craig V.M. Barton, Carl Bernacchi, Carlo Calfapietra, Kristine Y. Crous, Mirindi Eric Dusenge, Teresa E. Gimeno, Marianne Hall, Shubhangi Lamba, Sebastian Leuzinger, Johan Uddling, Jeffrey Warren, Göran Wallin, Belinda E. Medlyn

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Optimal stomatal theory predicts that stomata operate to maximise photosynthesis (Anet) and minimise transpirational water loss to achieve optimal intrinsic water-use efficiency (iWUE). We tested whether this theory can predict stomatal responses to elevated atmospheric CO2 (eCO2), and whether it can capture differences in responsiveness among woody plant functional types (PFTs). We conducted a meta-analysis of tree studies of the effect of eCO2 on iWUE and its components Anet and stomatal conductance (gs). We compared three PFTs, using the unified stomatal optimisation (USO) model to account for confounding effects of leaf–air vapour pressure difference (D). We expected smaller gs, but …

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Invasive Annual Grasses—Reenvisioning Approaches In A Changing Climate, David Archer, David Toledo, Dana M. Blumenthal, Justin Derner, Usda Ars Burns, Oregon, Kirk Davies, Erik Hamerlynck, Roger Sheley, Pat Clark, Fred Pierson, Charlie Clements, Beth Newingham, Brian Rector, John Gaskin, Carissa L. Wonkka, Kevin Jensen, Tom Monaco, Lance T. Vermeire, Stephen L. Young Feb 2023

Invasive Annual Grasses—Reenvisioning Approaches In A Changing Climate, David Archer, David Toledo, Dana M. Blumenthal, Justin Derner, Usda Ars Burns, Oregon, Kirk Davies, Erik Hamerlynck, Roger Sheley, Pat Clark, Fred Pierson, Charlie Clements, Beth Newingham, Brian Rector, John Gaskin, Carissa L. Wonkka, Kevin Jensen, Tom Monaco, Lance T. Vermeire, Stephen L. Young

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

For nearly a century, invasive annual grasses have increasingly impacted terrestrial ecosystems across the western United States. Weather variability associated with climate change and increased atmospheric carbon dioxide (CO2) are making even more difficult the challenges of managing invasive annual grasses. As part of a special issue on climate change impacts on soil and water conservation, the topic of invasive annual grasses is being addressed by scientists at the USDA Agricultural Research Service to emphasize the need for additional research and future studies that build on current knowledge and account for (extreme) changes in abiotic and biotic conditions. Much research …

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Salty: A Diffractive Inquiry Of Visceral Knowing And Embodied Aesthetics, Mei Ling Chua Feb 2023

Salty: A Diffractive Inquiry Of Visceral Knowing And Embodied Aesthetics, Mei Ling Chua

Dissertations, Theses, and Capstone Projects

This dissertation takes a diffractive, onto-epistemological approach to everyday practices with salt in order to articulate an expanded understanding of meaning making and knowledge production. This research reckons with and challenges dominant modes of knowing that engage a Cartesian perspective to situate knowing as the exclusive domain of the mind in both form and topic of inquiry. This research acts simultaneously as both a direct practice of and metacognition about knowledge production by examining 1. the embodied (including sensory and emotional aspects) and 2. the relational (including interpersonal and socio-cultural) dimensions of experience as visceral knowing. This articulation of …

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It Has Always Been The “Business Model”: Racism And Sexism In Creative Arts Therapy Higher Education, Yasmine J. Awais Feb 2023

It Has Always Been The “Business Model”: Racism And Sexism In Creative Arts Therapy Higher Education, Yasmine J. Awais

Dissertations, Theses, and Capstone Projects

Part of the Neoliberal drive is to privatize the structure and operation of public and private organizations and institutions. Managerialism has shaped higher education since the mid to late 1970s through a focus on productivity, efficiency, accountability, and standardization. Workers employed in social service organizations and universities have employed strategies for managing organizations based on the neoliberal business philosophy for the last 40 years. This research examines the impact of managerialism in higher education through the experience of faculty teaching in creative arts therapy master’s professional programs. During 2021, twenty-three faculty of color and white faculty who identified as women …

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Nanoscale Imaging Of Electrocatalytic Nanomaterials By High-Resolution Scanning Electrochemical Microscopy, Xiang Wang Feb 2023

Nanoscale Imaging Of Electrocatalytic Nanomaterials By High-Resolution Scanning Electrochemical Microscopy, Xiang Wang

Dissertations, Theses, and Capstone Projects

Numerous insights of the structure–electrochemical activity relationship of nanocatalysts have been obtained by using macroscopic electrochemical measurements over the last several decades. However, signals measured by large electrodes are inevitably averaged out of many nanocatalysts, non-uniformed sizes, uneven morphologies, and multiple crystallographic facets. Over the last ten years, Scanning Electrochemical Microscopy (SECM) has advanced electrochemical measurements toward micro- to nanoscale level at a high spatial resolution. The advantages of using nanoelectrode in SECM include fast mass transfer of reactive species, dominated radial diffusion pattern, small double layer capacitance and small RC constant. In this thesis, high-resolution SECM is applied to …

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Race, Gender, Physical Activity, And Cancer: A Quantitative Investigation, Shawna A. Townsend Feb 2023

Race, Gender, Physical Activity, And Cancer: A Quantitative Investigation, Shawna A. Townsend

Dissertations, Theses, and Capstone Projects

Black women are more likely to die from cancer than any other population in the United States. Physical activity is known to be associated with preventing and reducing cancer burden. However, Black women are less physically active than their White counterparts and have a higher prevalence of diseases related to lack of physical activity than any other female group. To better understand these issues, this study employed the self-and-family management framework and intersectionality as theoretical frameworks through a secondary analysis of the Health Information National Trends Survey (HINTS) dataset and hierarchical regression modeling to examine the relative impact of (a.) …

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Coloniality, Western Science, And Critical Ethnic Studies In Stem Education, Latoya M. Strong Feb 2023

Coloniality, Western Science, And Critical Ethnic Studies In Stem Education, Latoya M. Strong

Dissertations, Theses, and Capstone Projects

In this dissertation, I use a critical transdisciplinary approach to examine how the coloniality of Western Science impacts science education teaching, learning, and research. Weaving together Black geographies, settler colonialism, and decolonial theory, I illustrate how the historical, symbiotic relationship between colonization and Western Science created a culture that continues to shape modern science practices and science education. The coloniality of Western Science was codified into science education, resulting in three approaches to teaching, learning and research—the assimilationist model, the capitalist model, and the imperialist model. Moving from theory to research, I collaborated with STEM educators over six weeks to …

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Quantifying Psychostimulant-Induced Sensitization Effects On Dopamine And Acetylcholine Release Across Different Timescales, Georg Lange Feb 2023

Quantifying Psychostimulant-Induced Sensitization Effects On Dopamine And Acetylcholine Release Across Different Timescales, Georg Lange

Dissertations, Theses, and Capstone Projects

Drug-induced behavioral sensitization describes the phenomenon that behavioral response to a drug of abuse is getting stronger if the same psychostimulant is delivered multiple times which is much more pronounced if done in the same environmental context. A proposed neural basis is the formation of an association between contextual cues and the rewarding drug which is mediated by dopamine. Dopamine operates at different timescales and to fully understand dopamine sensitization, it is necessary to investigate dopamine release at slow (tens of minutes) but also faster (sub-second) timescales. But creating a holistic view has been difficult due to a lack of …

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Second Generation Phenyloxadiazolyl Methyl Sulfones For Thiol-Specific Bioconjugations, Guillaume Dewaele-Le Roi Feb 2023

Second Generation Phenyloxadiazolyl Methyl Sulfones For Thiol-Specific Bioconjugations, Guillaume Dewaele-Le Roi

Dissertations, Theses, and Capstone Projects

The role of antibody-based molecular agents for diagnosis and therapy of cancer has expanded significantly over the past decades. However, most of these constructs are synthesized using traditional bioconjugation methods based on the random ligations between the molecular cargo and lysine residues within the protein. These non-specific approaches can create poorly defined conjugates with suboptimal immunoreactivity and in vivo performance while Site-specific approaches to antibody bioconjugation based on ligations between maleimides and free cysteine residues have long stood as attractive alternatives. Yet the inherent instability of the thiol-maleimide linkage has fueled the search for new, more stable thiol-reactive prosthetic groups. …

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Chromatic Dissensus: An Otherwise Archive Of Natural Dyes, 1700–1856, Luke Church Feb 2023

Chromatic Dissensus: An Otherwise Archive Of Natural Dyes, 1700–1856, Luke Church

Dissertations, Theses, and Capstone Projects

Chromatic Dissensus: An Otherwise Archive of Natural Dyes, 1750-1856 works from the premise that the absences regarding subaltern life structuring the colonial archive are an epistemological problem—that is, navigating the colonial archive requires an interrogation of the parameters and practices of knowledge formation. Building from recent scholarship in early American studies which details how eighteenth-century colonial knowledge developed out of an epistemic entanglement between British colonists, diasporic Africans, and indigenous Americans, my dissertation queries the overdetermination of colonial knowledge and subsequent occlusion of alternative parameters for knowing. Enlisting aesthetics, in its broad definition as the theorization of sense making, my …

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Renal Involvement As A Potential Feature Of Pyogenic Arthritis, Pyoderma Gangrenosum, And Acne Syndrome With E250k Mutation Of Pstpip1 Gene, Raymond Zhao, Taylor Novice, Sasank Konda Feb 2023

Renal Involvement As A Potential Feature Of Pyogenic Arthritis, Pyoderma Gangrenosum, And Acne Syndrome With E250k Mutation Of Pstpip1 Gene, Raymond Zhao, Taylor Novice, Sasank Konda

Dermatology Articles

No abstract provided.

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Quantification Of Age-Related Changes In The Lateral Organization Of The Lipid Portion Of The Intact Membranes Isolated From The Left And Right Eye Lenses Of The Same Human Donor, Laxman Mainali, Marija Raguz, Witold Karol Subczynski Feb 2023

Quantification Of Age-Related Changes In The Lateral Organization Of The Lipid Portion Of The Intact Membranes Isolated From The Left And Right Eye Lenses Of The Same Human Donor, Laxman Mainali, Marija Raguz, Witold Karol Subczynski

Physics Faculty Publications and Presentations

The continuous wave EPR spin-labeling method was used to evaluate age-related changes in the amounts of phospholipids (PLs) and cholesterol (Chol) in domains present in intact, cortical, and nuclear fiber cell plasma membranes isolated separately from the left and right eye lenses of the same human donor. The relative amounts of boundary plus trapped PLs were evaluated with the PL analog 12-doxylstearic acid spin label (12-SASL) and the relative amounts of trapped Chol with the Chol analog androstane spin label (ASL). The donors ranged in age from 15 to 70 years. Both the left and right eye lenses from donors …

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February 1, 2023 (Vol. 107, No. 18), Daily Eastern News Feb 2023

February 1, 2023 (Vol. 107, No. 18), Daily Eastern News

Daily Eastern News: 2022-2023

No abstract provided.

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Blanding’S Turtle (Emydoidea Blandingii): Species Conservation Assessment, Melissa J. Panella, Colleen Rothe-Groleau Feb 2023

Blanding’S Turtle (Emydoidea Blandingii): Species Conservation Assessment, Melissa J. Panella, Colleen Rothe-Groleau

Nebraska Game and Parks Commission: Publications

The primary goal in development of at-risk species conservation assessments is to compile biological and ecological information that may assist conservation practitioners in making decisions regarding the conservation of species of interest. The Nebraska Natural Legacy Project recognizes the Blanding’s turtle (Emydoidea blandingii) as a Tier 1 at-risk species. Some general management recommendations are made here regarding Blanding’s turtles; however, conservation practitioners will need to use professional judgment to make specific management decisions based on objectives, location, and a multitude of variables. This resource was designed to share available knowledge of this at-risk turtle that will aid in the decision-making …

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