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2023

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The Constitutionality Of The Indian Child Welfare Act, Emily Hudson Feb 2023

The Constitutionality Of The Indian Child Welfare Act, Emily Hudson

Ohio Northern University Law Review

No abstract provided.


The Morality Of The Presidential Oath, Evan D. Bernick Feb 2023

The Morality Of The Presidential Oath, Evan D. Bernick

Ohio Northern University Law Review

No abstract provided.


Tax Credits Vs. Corporate Social Responsibility: Theentertainment Industry’S Challenge To State Anti-Abortion Bills, Robert Rosenberg Feb 2023

Tax Credits Vs. Corporate Social Responsibility: Theentertainment Industry’S Challenge To State Anti-Abortion Bills, Robert Rosenberg

Ohio Northern University Law Review

No abstract provided.


Privacy And Its Importance With Advancing Technology, Judith Wagner Decew Feb 2023

Privacy And Its Importance With Advancing Technology, Judith Wagner Decew

Ohio Northern University Law Review

No abstract provided.


Untested Drugs To Treat Ebola: A Case Of Uncompassionatecompassionate Use?, Stacey B. Lee J.D. Feb 2023

Untested Drugs To Treat Ebola: A Case Of Uncompassionatecompassionate Use?, Stacey B. Lee J.D.

Ohio Northern University Law Review

No abstract provided.


What Do An Orangutan And A Corporation Have In Common?:Whether The Copyright Protection Afforded To Corporationsshould Extend To Works Created By Animals, Holly C. Lynch Feb 2023

What Do An Orangutan And A Corporation Have In Common?:Whether The Copyright Protection Afforded To Corporationsshould Extend To Works Created By Animals, Holly C. Lynch

Ohio Northern University Law Review

No abstract provided.


Building Legal Competencies:The Montessori Method As A Unifying Approach Tooutcomes-Based Assessment In Law Schools, Abigail Loftus Deblasis Feb 2023

Building Legal Competencies:The Montessori Method As A Unifying Approach Tooutcomes-Based Assessment In Law Schools, Abigail Loftus Deblasis

Ohio Northern University Law Review

No abstract provided.


Life On The Mississippi: Reducing The Harmful Effects Ofagricultural Runoff In The Mississippi River Basin, Taylor A. Beaty Feb 2023

Life On The Mississippi: Reducing The Harmful Effects Ofagricultural Runoff In The Mississippi River Basin, Taylor A. Beaty

Ohio Northern University Law Review

No abstract provided.


Law’S Failure To Keep Pace With Empirical Science: Anexamination Of Personality And Emotional Intelligence Testing Inthe Workplace, H. Beau Baez Iii Feb 2023

Law’S Failure To Keep Pace With Empirical Science: Anexamination Of Personality And Emotional Intelligence Testing Inthe Workplace, H. Beau Baez Iii

Ohio Northern University Law Review

No abstract provided.


Constitutional Constraints On Second Parent Laws, Jeffrey A. Parness Feb 2023

Constitutional Constraints On Second Parent Laws, Jeffrey A. Parness

Ohio Northern University Law Review

No abstract provided.


The Three Waves Of Married Women’S Property Acts In Thenineteenth Century With A Focus On Mississippi,New York, And Oregon, Joseph A. Custer Feb 2023

The Three Waves Of Married Women’S Property Acts In Thenineteenth Century With A Focus On Mississippi,New York, And Oregon, Joseph A. Custer

Ohio Northern University Law Review

No abstract provided.


Inheritance Of Frozen Reproductive Material, Elise N. Mcquain Feb 2023

Inheritance Of Frozen Reproductive Material, Elise N. Mcquain

Ohio Northern University Law Review

No abstract provided.


Biology Professors, Students Conduct Dna Research, Taylor University Feb 2023

Biology Professors, Students Conduct Dna Research, Taylor University

2023 Website News Stories

No abstract provided.


Revisiting Ethnic Differences In In-Person Learning During 2021-2022, Andrew Camp, Alison H. Johnson, Gema Zamarro Feb 2023

Revisiting Ethnic Differences In In-Person Learning During 2021-2022, Andrew Camp, Alison H. Johnson, Gema Zamarro

Education Reform Faculty and Graduate Students Publications

During the 2020-21 school year, Black and Hispanic students were less likely to attend school in-person than white students. Prior research indicated multiple factors helped explain this gap. In this study, we revise these observed racial gaps in in-person learning to examine whether the relationship between these gaps and explanatory factors observed earlier in the pandemic changed during the 2021-2022 school year. We find that, while in-person gaps decreased, Black respondents continued to be less likely to report in-person learning than white respondents. Political leanings and COVID-19 health risks, which helped explain observed gaps in 2020-2021, lose explanatory power. But …


Myostatin: A Skeletal Muscle Chalone., Se-Jin Lee Feb 2023

Myostatin: A Skeletal Muscle Chalone., Se-Jin Lee

Faculty Research 2023

Myostatin (GDF-8) was discovered 25 years ago as a new transforming growth factor-β family member that acts as a master regulator of skeletal muscle mass. Myostatin is made by skeletal myofibers, circulates in the blood, and acts back on myofibers to limit growth. Myostatin appears to have all of the salient properties of a chalone, which is a term proposed over a half century ago to describe hypothetical circulating, tissue-specific growth inhibitors that control tissue size. The elucidation of the molecular, cellular, and physiological mechanisms underlying myostatin activity suggests that myostatin functions as a negative feedback regulator of muscle mass …


Hucopia: An Atlas Of Human Vs. Sars-Cov-2 Interactome And The Comparative Analysis With Other Coronaviridae Family Viruses, Naveen Duhan, Rakesh Kaundal Feb 2023

Hucopia: An Atlas Of Human Vs. Sars-Cov-2 Interactome And The Comparative Analysis With Other Coronaviridae Family Viruses, Naveen Duhan, Rakesh Kaundal

Plants, Soils, and Climate Faculty Publications

SARS-CoV-2, a novel betacoronavirus strain, has caused a pandemic that has claimed the lives of nearly 6.7M people worldwide. Vaccines and medicines are being developed around the world to reduce the disease spread, fatality rates, and control the new variants. Understanding the protein-protein interaction mechanism of SARS-CoV-2 in humans, and their comparison with the previous SARS-CoV and MERS strains, is crucial for these efforts. These interactions might be used to assess vaccination effectiveness, diagnose exposure, and produce effective biotherapeutics. Here, we present the HuCoPIA database, which contains approximately 100,000 protein-protein interactions between humans and three strains (SARS-CoV-2, SARS-CoV, and MERS) …


2023 Furman University Faculty Scholarship Reception Program, Kathy Hamlin, Madeline Shaw Feb 2023

2023 Furman University Faculty Scholarship Reception Program, Kathy Hamlin, Madeline Shaw

Libraries Institutional Records

On February 10, 2023, the Libraries and the Office of the Provost hosted Furman’s sixth Faculty Scholarship Reception. The reception showcased accomplishments from the 2022 calendar year, highlighting Furman faculty members who have completed a degree, received a grant from an external funding source totaling more than $1,000, and/or published books, book chapters, journal articles, exhibits, recordings, performances, films, or other works. The following faculty provided four-minute presentations on their scholarly or creative works:

  • Mahan Ellison, Associate Professor of Modern Languages and Literatures
  • Bronwen Forbay, Visiting Associate Professor of Voice
  • James Guth, Professor of Politics and International Affairs
  • Nick Radel, …


Photoprotection For People With Skin Of Colour: Needs And Strategies, Jean Krutmann, Jaime Piquero-Casals, Daniel Morgado-Carrasco, Corinne Granger, Carles Trullàs, Thierry Passeron, Henry W. Lim Feb 2023

Photoprotection For People With Skin Of Colour: Needs And Strategies, Jean Krutmann, Jaime Piquero-Casals, Daniel Morgado-Carrasco, Corinne Granger, Carles Trullàs, Thierry Passeron, Henry W. Lim

Dermatology Articles

Skin of colour or pigmented skin has unique characteristics: it has a higher eumelanin-to-pheomelanin ratio, more mature melanosomes, an increased amount of melanin distributed in the upper layers of the epidermis, and more efficient DNA repair compared with lighter skin. However, individuals with skin of colour are at a significant risk of skin damage caused by ultraviolet radiation, including the development of photodermatoses and photoageing changes such as uneven skin tone, and are predisposed to pigmentary disorders. In fact, one of the most common conditions leading to dermatology consultations by patients with skin of colour is photoexacerbated pigmentary disorders. Unfortunately, …


Investigating Evidence-Based Practices And Interventions Using Multifaceted Learning Theory For Students In A Special Education Self-Contained Classroom, Adam Maitland Feb 2023

Investigating Evidence-Based Practices And Interventions Using Multifaceted Learning Theory For Students In A Special Education Self-Contained Classroom, Adam Maitland

Ed.D. Dissertations

Teachers working in a special education self-contained classroom were required to implement evidence-based practices and interventions, rarely researched in a school setting, with fidelity to meet the needs of students with intellectual disabilities. Evidence-based practices and interventions for students with intellectual disabilities were researched in clinical settings with one to three student participants and without a common evaluation tool. The purpose of this qualitative case study was to use the Tennessee Educator Acceleration Model General Educator Rubric to investigate how experienced teachers used multifaceted learning theory when implementing evidence-based practices and interventions in a diverse special education self-contained classroom to …


Comparative Pharmacology Of A Bis-Pivaloyloxymethyl Phosphonate Prodrug Inhibitor Of Enolase After Oral And Parenteral Administration, Victoria C Yan, Yasaman Barekatain, Yu-Hsi Lin, Nikunj Satani, Naima Hammoudi, Kenisha Arthur, Dimitra K Georgiou, Yongying Jiang, Yuting Sun, Joseph R Marszalek, Steven W Millward, Florian L Muller Feb 2023

Comparative Pharmacology Of A Bis-Pivaloyloxymethyl Phosphonate Prodrug Inhibitor Of Enolase After Oral And Parenteral Administration, Victoria C Yan, Yasaman Barekatain, Yu-Hsi Lin, Nikunj Satani, Naima Hammoudi, Kenisha Arthur, Dimitra K Georgiou, Yongying Jiang, Yuting Sun, Joseph R Marszalek, Steven W Millward, Florian L Muller

Faculty, Staff and Student Publications

Metabolically labile prodrugs can experience stark differences in catabolism incurred by the chosen route of administration. This is especially true for phosph(on)ate prodrugs, in which successive promoiety removal transforms a lipophilic molecule into increasingly polar compounds. We previously described a phosphonate inhibitor of enolase (HEX) and its bis-pivaloyloxymethyl ester prodrug (POMHEX) capable of eliciting strong tumor regression in a murine model of enolase 1 (ENO1)-deleted glioblastoma following parenteral administration. Here, we characterize the pharmacokinetics and pharmacodynamics of these enolase inhibitors in vitro and in vivo after oral and parenteral administration. In support of the historical function of lipophilic …


Celebrate Darwin Day 2023 With Uab's Department Of Biology, Micah Hardge Feb 2023

Celebrate Darwin Day 2023 With Uab's Department Of Biology, Micah Hardge

Browse All News

No abstract provided.


A Phase Ib/Ii Study Of Lenvatinib And Pembrolizumab In Advanced Endometrial Carcinoma (Study 111/Keynote-146): Long-Term Efficacy And Safety Update., Vicky Makker, Carol Aghajanian, Allen L Cohn, Margarita Romeo, Raquel Bratos, Marcia S Brose, Mark Messing, Lea Dutta, Corina E Dutcus, Jie Huang, Emmett V Schmidt, Robert Orlowski, Matthew H Taylor Feb 2023

A Phase Ib/Ii Study Of Lenvatinib And Pembrolizumab In Advanced Endometrial Carcinoma (Study 111/Keynote-146): Long-Term Efficacy And Safety Update., Vicky Makker, Carol Aghajanian, Allen L Cohn, Margarita Romeo, Raquel Bratos, Marcia S Brose, Mark Messing, Lea Dutta, Corina E Dutcus, Jie Huang, Emmett V Schmidt, Robert Orlowski, Matthew H Taylor

Department of Medicine Faculty Papers

Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has already been reported.The open-label phase Ib/II Study 111/KEYNOTE-146 of daily lenvatinib 20 mg plus pembrolizumab 200 mg once every 3 weeks showed promising efficacy and tolerable safety in patients with previously treated advanced endometrial carcinoma (EC; primary data cutoff …


Dissertation Chapters Underway: 10,000 Shards, Or Opening And Activating Depth: Handicraft, Value, And The Work Of Art (Shards 00000-00001), Christopher Southward, Christopher Southward Feb 2023

Dissertation Chapters Underway: 10,000 Shards, Or Opening And Activating Depth: Handicraft, Value, And The Work Of Art (Shards 00000-00001), Christopher Southward, Christopher Southward

Comparative Literature Faculty and Student Scholarship

Dissertation Chapters Underway: 10,000 Shards, Or Opening and Activating Depth: Handicraft, Value, and the Work of Art (Shards 00000-00001), Christopher Southward


The Colonial Origins Of Institutions In Mauritanina, Mahfoudha Sidelemine Feb 2023

The Colonial Origins Of Institutions In Mauritanina, Mahfoudha Sidelemine

Graduate Research Conference (GSIS)

This paper examines and evaluates the state of development in Mauritania, a former French colony in West Africa. The drivers of (under)development that the paper focuses on are institutions. By focusing on institutions as the main factors that determine the development process of the country, I also focus on the colonial origins of institutions. Hence, in this paper, I draw on Acemoglu and colleagues’ argument on the origin of colonial origins of institutions as they identify two types of colonial institutions—Inclusive and Exclusive (Acemoglu et.al.2001). However, in this research, I argue that there is a third type of institution the …


Plant Community Patterns And A Flora Of Six Lower Mississippi River Islands, Grace Leia Mccartha Feb 2023

Plant Community Patterns And A Flora Of Six Lower Mississippi River Islands, Grace Leia Mccartha

Student Theses and Dissertations

Lower Mississippi River islands experience intense flood regimes that result in a supply of sediment and seeds from upstream. The islands are some of the last remaining floodplain habitats in the Delta region, and surveying their botanical diversity is important for learning about floodplain plant community structure. From June 2020 through December 2021, I conducted a flora of six Lower Mississippi River islands from Helena-West Helena, Arkansas, to Greenville, Mississippi. I collected 2,310 plant specimens for a total of 491 taxa, including five taxa not previously recorded in Arkansas and seven not previously recorded in Mississippi. From mid-July to late-August …


Automation Of Irrigation To Improve Outcomes Of Agronomic Crops: On-Farm And Modeling Demonstrations, Thais Murias Jardim Feb 2023

Automation Of Irrigation To Improve Outcomes Of Agronomic Crops: On-Farm And Modeling Demonstrations, Thais Murias Jardim

Student Theses and Dissertations

Automated irrigation systems and new management practices may help address aquifer depletion, labor shortages, and irrigation management challenges. This study evaluated the impact of various automated irrigation systems on commercial farms that produce maize, rice, and soybean. It also modeled how Early Cascade Rice Irrigation Shutoff (ECIS) performs under a range of field conditions. Growers observed various benefits of using automated systems other than irrigation savings or yield increase. Timers and remote shutoff are the most practical and beneficial options for growers willing to adopt some level of automation. ECIS modeling estimates showed that applied irrigation and runoff decreased as …


Automated Contouring And Planning In Radiation Therapy: What Is 'Clinically Acceptable'?, Hana Baroudi, Kristy K Brock, Wenhua Cao, Xinru Chen, Caroline Chung, Laurence E Court, Mohammad D El Basha, Maguy Farhat, Skylar Gay, Mary P Gronberg, Aashish Chandra Gupta, Soleil Hernandez, Kai Huang, David A Jaffray, Rebecca Lim, Barbara Marquez, Kelly Nealon, Tucker J Netherton, Callistus M Nguyen, Brandon Reber, Dong Joo Rhee, Ramon M Salazar, Mihir D Shanker, Carlos Sjogreen, Mckell Woodland, Jinzhong Yang, Cenji Yu, Yao Zhao Feb 2023

Automated Contouring And Planning In Radiation Therapy: What Is 'Clinically Acceptable'?, Hana Baroudi, Kristy K Brock, Wenhua Cao, Xinru Chen, Caroline Chung, Laurence E Court, Mohammad D El Basha, Maguy Farhat, Skylar Gay, Mary P Gronberg, Aashish Chandra Gupta, Soleil Hernandez, Kai Huang, David A Jaffray, Rebecca Lim, Barbara Marquez, Kelly Nealon, Tucker J Netherton, Callistus M Nguyen, Brandon Reber, Dong Joo Rhee, Ramon M Salazar, Mihir D Shanker, Carlos Sjogreen, Mckell Woodland, Jinzhong Yang, Cenji Yu, Yao Zhao

Faculty, Staff and Student Publications

Developers and users of artificial-intelligence-based tools for automatic contouring and treatment planning in radiotherapy are expected to assess clinical acceptability of these tools. However, what is 'clinical acceptability'? Quantitative and qualitative approaches have been used to assess this ill-defined concept, all of which have advantages and disadvantages or limitations. The approach chosen may depend on the goal of the study as well as on available resources. In this paper, we discuss various aspects of 'clinical acceptability' and how they can move us toward a standard for defining clinical acceptability of new autocontouring and planning tools.


Pearl Millet Response To Drought: A Review, Nikee Shrestha, Hao Hu, Kumar Shrestha, Andrew N. Doust Feb 2023

Pearl Millet Response To Drought: A Review, Nikee Shrestha, Hao Hu, Kumar Shrestha, Andrew N. Doust

Department of Agronomy and Horticulture: Faculty Publications

The C4 grass pearl millet is one of the most drought tolerant cereals and is primarily grown in marginal areas where annual rainfall is low and intermittent. It was domesticated in sub-Saharan Africa, and several studies have found that it uses a combination of morphological and physiological traits to successfully resist drought. This review explores the short term and long-term responses of pearl millet that enables it to either tolerate, avoid, escape, or recover from drought stress. The response to short term drought reveals fine tuning of osmotic adjustment, stomatal conductance, and ROS scavenging ability, along with ABA and ethylene …


Challenging Breast Cancer Through Novel Sulfonamide–Pyridine Hybrids: Design, Synthesis, Carbonic Anhydrase Ix Inhibition And Induction Of Apoptosis., Amira Khalil, Nashwa H. Zaher, Reham Mm Elhazek, Ahmed E. Gouda, Marwa G. Elgazzar Feb 2023

Challenging Breast Cancer Through Novel Sulfonamide–Pyridine Hybrids: Design, Synthesis, Carbonic Anhydrase Ix Inhibition And Induction Of Apoptosis., Amira Khalil, Nashwa H. Zaher, Reham Mm Elhazek, Ahmed E. Gouda, Marwa G. Elgazzar

Pharmacy

Background: Among the important key modulators of the tumor microenvironment and hypoxia is a family of enzymes named carbonic anhydrases. Herein, 11 novel sulfonamide–pyridine hybrids (2–12) were designed, synthesized and biologically evaluated for their potential use in targeting breast cancer. Methods & results: The para chloro derivative 7 reported the highest cytotoxic activity against the three breast cancer cell lines used. In addition, compound 7 was found to induce cell cycle arrest and autophagy as well as delaying wound healing. The IC50 of compound 7 against carbonic anhydrase IX was 253 ± 12 nM using dorzolamide HCl as control. Conclusion: …


Extinction Or Bust: Improving Species Recovery Under The Endangered Species Act By Amending The Funding Allocation And Recovery Planning Processes, Max Hayashi Feb 2023

Extinction Or Bust: Improving Species Recovery Under The Endangered Species Act By Amending The Funding Allocation And Recovery Planning Processes, Max Hayashi

Texas A&M Law Review

The Endangered Species Act of 1973 (“ESA”) is among the most powerful environmental statutes passed in U.S. history and serves as a blueprint for government-sanctioned conservation efforts globally. At its core, the ESA seeks to protect listed plant and animal species by prohibiting actions that harm their chances of survival. While the ESA has generally succeeded in pursuing this goal as implemented, it has also led to a host of problems that undermine its effectiveness and generated widespread discontent among conflicting, disparate stakeholders, including environmentalists, industry groups, government agencies, and private landowners. Criticisms of the ESA generally focus on several …