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2023

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Articles 23281 - 23310 of 35350

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The Perceived Impact Of Faculty-In-Residence Programs On Faculty Development, Luis Arabit, Leonard Lira, Jennifer Johnston, Lina Anastasovitou, Christine Ma-Kellams, Kyle Hambrook, Ravneet Tiwana, Theodore T. Tsau Mar 2023

The Perceived Impact Of Faculty-In-Residence Programs On Faculty Development, Luis Arabit, Leonard Lira, Jennifer Johnston, Lina Anastasovitou, Christine Ma-Kellams, Kyle Hambrook, Ravneet Tiwana, Theodore T. Tsau

Faculty Research, Scholarly, and Creative Activity

Faculty-in-Residence (FIR) programs, where students interact with faculty outside of the classroom, have shown positive effects on student success. However, most research does not look at FIR programs from a holistic perspective that examines the impact on faculty. This study investigates the perceived impact on faculty participating in FIR programs. The results add to current literature that faculty-student interactions outside of the classroom are significant for students and faculty, specifically faculty perceptions of performance in teaching and service. The results also indicate positive perceptions by faculty in research performance due to participation in the FIR program. This finding is surprising …

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Adipose-Targeted Swell1 Deletion Exacerbates Obesity- And Age-Related Nonalcoholic Fatty Liver Disease, Susheel K. Gunasekar, John Heebink, Danielle H Carpenter, Ashutosh Kumar, Litao Xie, Haixia Zhang, Joel D. Schilling, Rajan Sah Mar 2023

Adipose-Targeted Swell1 Deletion Exacerbates Obesity- And Age-Related Nonalcoholic Fatty Liver Disease, Susheel K. Gunasekar, John Heebink, Danielle H Carpenter, Ashutosh Kumar, Litao Xie, Haixia Zhang, Joel D. Schilling, Rajan Sah

2020-Current year OA Pubs

Healthy expansion of adipose tissue is critical for the maintenance of metabolic health, providing an optimized reservoir for energy storage in the form of triacylglycerol-rich lipoproteins. Dysfunctional adipocytes that are unable to efficiently store lipid can result in lipodystrophy and contribute to nonalcoholic fatty liver disease (NAFLD) and metabolic syndrome. Leucine-rich repeat containing protein 8a/SWELL1 functionally encodes the volume-regulated anion channel complex in adipocytes, is induced in early obesity, and is required for normal adipocyte expansion during high-fat feeding. Adipose-specific SWELL1 ablation (Adipo KO) leads to insulin resistance and hyperglycemia during caloric excess, both of which are associated with NAFLD. …

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Microbiology Clinical Culture Diagnostic Yields And Antimicrobial Resistance Proportions Before And During The Covid-19 Pandemic In An Indian Community Hospital And Two Us Community Hospitals, Sumanth Gandra, Gerardo Alvarez-Uria, Dustin Stwalley, Katelin B Nickel, Kimberly A Reske, Jennie H Kwon, Erik R Dubberke, Margaret A Olsen, Jason P Burnham Mar 2023

Microbiology Clinical Culture Diagnostic Yields And Antimicrobial Resistance Proportions Before And During The Covid-19 Pandemic In An Indian Community Hospital And Two Us Community Hospitals, Sumanth Gandra, Gerardo Alvarez-Uria, Dustin Stwalley, Katelin B Nickel, Kimberly A Reske, Jennie H Kwon, Erik R Dubberke, Margaret A Olsen, Jason P Burnham

2020-Current year OA Pubs

Studies comparing the impact of the COVID-19 pandemic on diagnostic microbiology culture yields and antimicrobial resistance proportions in low-to-middle-income and high-income countries are lacking. A retrospective study using blood, respiratory, and urine microbiology data from a community hospital in India and two community hospitals (Hospitals A and B) in St. Louis, MO, USA was performed. We compared the proportion of cultures positive for selected multi-drug-resistant organisms (MDROs) listed on the WHO's priority pathogen list both before the COVID-19 pandemic (January 2017-December 2019) and early in the COVID-19 pandemic (April 2020-October 2020). The proportion of blood cultures contaminated with coagulase-negative

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Mafr 3d Skull, Kevin Rafferty, Briana K. Zaffiro, David W. Kerstetter Mar 2023

Mafr 3d Skull, Kevin Rafferty, Briana K. Zaffiro, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

3D Scan of a Magnificent Frigatebird

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Rosp 3d Skull (Roseate Spoonbill), Kevin Rafferty, Briana K. Zaffiro, David Kerstetter Mar 2023

Rosp 3d Skull (Roseate Spoonbill), Kevin Rafferty, Briana K. Zaffiro, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

3D skull of a roseate spoonbill

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Negotiating Emotional Order: A Grounded Theory Of The Survivorship Process In Women Who Have Completed Treatment For Breast Cancer, Jennifer A. Klimek Yingling Mar 2023

Negotiating Emotional Order: A Grounded Theory Of The Survivorship Process In Women Who Have Completed Treatment For Breast Cancer, Jennifer A. Klimek Yingling

Dissertations

Decades of research focusing on treatment and detection of breast cancer has promoted better outcomes in treating the disease and longer survival rates. Despite this there is a significant gap in the literatures regarding the survivorship process. Breast cancer survivorship needs to be fully understood by nurses and health care providers (HCP) in order to obtain optimal health outcomes for this ever growing population.

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Dual Vocations Of Science And Religion: A Historical Case Study Of Benedictine Women, Diana Fenton Mar 2023

Dual Vocations Of Science And Religion: A Historical Case Study Of Benedictine Women, Diana Fenton

Education Faculty Publications

This study examines Catholic Benedictine sisters who majored in sciences and taught science for over 100 years at the College of Saint Benedict in Saint Joseph, Minnesota, USA. In 1913, the College of Saint Benedict began as a women’s college, expanding Saint Benedict’s Academy, a boarding high school for women. This historical organizational case study analyzed archived data to understand the benefits and challenges of women who lived religious lives and studied science. Although women, in general, are still underrepresented in the sciences, the data collected provides information on how the sisters obtained advanced degrees as early as 1923, well …

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Once A Landscaper's Favorite, States Are Banning This Tree And Urging Homeowners To Cut It Down, Ryan W. Mcewan Mar 2023

Once A Landscaper's Favorite, States Are Banning This Tree And Urging Homeowners To Cut It Down, Ryan W. Mcewan

Materials from the University of Dayton Magazine Website

They’re beautiful in bloom, but Callery pear trees crowd out native plants and turn productive open land into woody thickets, writes University of Dayton biology professor Ryan W. McEwan.

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Jinx Mccombs Oral History Interview, Jinx Mccombs, Lorenzo Spaccarelli Mar 2023

Jinx Mccombs Oral History Interview, Jinx Mccombs, Lorenzo Spaccarelli

Raymond College

No abstract provided.

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Emotionally Concussed: The Impact Of Pre-Existing Anxiety On Concussion Recovery, Grace Szucs Mar 2023

Emotionally Concussed: The Impact Of Pre-Existing Anxiety On Concussion Recovery, Grace Szucs

Honors Program: Senior Projects (Public)

Recent advances in concussion research have shed light on numerous mental and physiological factors that may complicate concussion recovery. Systematic reviews of the existing literature have found that premorbid mental health conditions such as depression and anxiety may be a predictor of complicated concussion recovery, but studies have not had an appropriate design to isolate anxiety or depression as a predictor of lengthened recovery. This study investigated if athletes with a history of premorbid anxiety and/or depression would have a longer time of recovery than athletes without this history. Male and female athletes from a Division-1 athletic department treated for …

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Pragmatic, Prospective Comparative Effectiveness Trial Of Carbon Ion Therapy, Surgery, And Proton Therapy For The Management Of Pelvic Sarcomas (Soft Tissue/Bone) Involving The Bone: The Prosper Study Rationale And Design, Bradford S Hoppe, Ivy A Petersen, Benjamin K Wilke, Todd A Dewees, Reiko Imai, Eugen B Hug, Maria Rosaria Fiore, Jürgen Debus, Piero Fossati, Shigeru Yamada, Ester Orlandi, Qing Zhang, Cihang Bao, Katharina Seidensaal, Byron C May, Anna C Harrell, Matthew T Houdek, Laura A Vallow, Peter S Rose, Michael G Haddock, Jonathan B Ashman, Krista A Goulding, Steven Attia, Sunil Krishnan, Anita Mahajan, Robert L Foote, Nadia N Laack, Sameer R Keole, Chris J Beltran, Eric M Welch, Mohammed Karim, Safia K Ahmed Mar 2023

Pragmatic, Prospective Comparative Effectiveness Trial Of Carbon Ion Therapy, Surgery, And Proton Therapy For The Management Of Pelvic Sarcomas (Soft Tissue/Bone) Involving The Bone: The Prosper Study Rationale And Design, Bradford S Hoppe, Ivy A Petersen, Benjamin K Wilke, Todd A Dewees, Reiko Imai, Eugen B Hug, Maria Rosaria Fiore, Jürgen Debus, Piero Fossati, Shigeru Yamada, Ester Orlandi, Qing Zhang, Cihang Bao, Katharina Seidensaal, Byron C May, Anna C Harrell, Matthew T Houdek, Laura A Vallow, Peter S Rose, Michael G Haddock, Jonathan B Ashman, Krista A Goulding, Steven Attia, Sunil Krishnan, Anita Mahajan, Robert L Foote, Nadia N Laack, Sameer R Keole, Chris J Beltran, Eric M Welch, Mohammed Karim, Safia K Ahmed

Faculty, Staff and Student Publications

Surgical treatment of pelvic sarcoma involving the bone is the standard of care but is associated with several sequelae and reduced functional quality of life (QOL). Treatment with photon and proton radiotherapy is associated with relapse. Carbon ion radiotherapy (CIRT) may reduce both relapse rates and treatment sequelae. The PROSPER study is a tricontinental, nonrandomized, prospective, three-arm, pragmatic trial evaluating treatments of pelvic sarcoma involving the bone. Patients aged at least 15 years are eligible for inclusion. Participants must have an Eastern Cooperative Oncology Group Performance Status score of two or less, newly diagnosed disease, and histopathologic confirmation of pelvic …

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Pragmatic, Prospective Comparative Effectiveness Trial Of Carbon Ion Therapy, Surgery, And Proton Therapy For The Management Of Pelvic Sarcomas (Soft Tissue/Bone) Involving The Bone: The Prosper Study Rationale And Design, Bradford S Hoppe, Ivy A Petersen, Benjamin K Wilke, Todd A Dewees, Reiko Imai, Eugen B Hug, Maria Rosaria Fiore, Jürgen Debus, Piero Fossati, Shigeru Yamada, Ester Orlandi, Qing Zhang, Cihang Bao, Katharina Seidensaal, Byron C May, Anna C Harrell, Matthew T Houdek, Laura A Vallow, Peter S Rose, Michael G Haddock, Jonathan B Ashman, Krista A Goulding, Steven Attia, Sunil Krishnan, Anita Mahajan, Robert L Foote, Nadia N Laack, Sameer R Keole, Chris J Beltran, Eric M Welch, Mohammed Karim, Safia K Ahmed Mar 2023

Pragmatic, Prospective Comparative Effectiveness Trial Of Carbon Ion Therapy, Surgery, And Proton Therapy For The Management Of Pelvic Sarcomas (Soft Tissue/Bone) Involving The Bone: The Prosper Study Rationale And Design, Bradford S Hoppe, Ivy A Petersen, Benjamin K Wilke, Todd A Dewees, Reiko Imai, Eugen B Hug, Maria Rosaria Fiore, Jürgen Debus, Piero Fossati, Shigeru Yamada, Ester Orlandi, Qing Zhang, Cihang Bao, Katharina Seidensaal, Byron C May, Anna C Harrell, Matthew T Houdek, Laura A Vallow, Peter S Rose, Michael G Haddock, Jonathan B Ashman, Krista A Goulding, Steven Attia, Sunil Krishnan, Anita Mahajan, Robert L Foote, Nadia N Laack, Sameer R Keole, Chris J Beltran, Eric M Welch, Mohammed Karim, Safia K Ahmed

Faculty, Staff and Student Publications

Surgical treatment of pelvic sarcoma involving the bone is the standard of care but is associated with several sequelae and reduced functional quality of life (QOL). Treatment with photon and proton radiotherapy is associated with relapse. Carbon ion radiotherapy (CIRT) may reduce both relapse rates and treatment sequelae. The PROSPER study is a tricontinental, nonrandomized, prospective, three-arm, pragmatic trial evaluating treatments of pelvic sarcoma involving the bone. Patients aged at least 15 years are eligible for inclusion. Participants must have an Eastern Cooperative Oncology Group Performance Status score of two or less, newly diagnosed disease, and histopathologic confirmation of pelvic …

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Optimization Of Cryo-Electron Microscopy For Quantitative Analysis Of Lipid Bilayers, Frederick A Heberle, Doug Welsch, Haden L Scott, M Neal Waxham Mar 2023

Optimization Of Cryo-Electron Microscopy For Quantitative Analysis Of Lipid Bilayers, Frederick A Heberle, Doug Welsch, Haden L Scott, M Neal Waxham

Faculty, Staff and Student Publications

Cryogenic electron microscopy (cryo-EM) is among the most powerful tools available for interrogating nanoscale structure of biological materials. We recently showed that cryo-EM can be used to measure the bilayer thickness of lipid vesicles and biological membranes with subangstrom precision, resulting in the direct visualization of nanoscopic domains of different thickness in multicomponent lipid mixtures and giant plasma membrane vesicles. Despite the great potential of cryo-EM for revealing the lateral organization of biomembranes, a large parameter space of experimental conditions remains to be optimized. Here, we systematically investigate the influence of instrument parameters and image postprocessing steps on the ability …

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Reduced Fire Severity Offers Near-Term Buffer To Climate-Driven Declines In Conifer Resilience Across The Western United States, Kimberley T. Davis, Marcos D. Robles, Kerry B. Kemp, Philip E. Higuera, Teresa Chapman, Kerry L. Metlen, Jamie L. Peeler, Kyle C. Rodman, Travis Woolley, Robert N. Addington, Brian J. Buma, Alina C. Cansler, Michael J. Case, Brandon M. Collins, Jonathan D. Coop, Solomon Z. Dobrowski, Nathan S. Gill, Collin Haffey, Lucas B. Harris, Brian J. Harvey, Ryan D. Haugo, Matthew D. Hurteau, Dominik Kulakowski, Caitlin E. Littlefield, Lisa A. Mccauley, Nicholas Povak, Kristen L. Shive, Edward Smith, Jens T. Stevens, Camille S. Stevens-Rumann, Alan H. Taylor, Alan J. Tepley, Derek J.N. Young, Robert A. Andrus, Mike A. Battaglia, Julia K. Berkey, Sebastian U. Busby, Amanda R. Carlson, Marin E. Chambers, Erich Kyle Dodson, Daniel Donato, William M. Downing, Paula J. Fornwalt, Joshua S. Halofsky, Ashley Hoffman, Andrés Holz, Jose M. Iniguez, Meg A. Krawchuk, Mark R. Krieder, Andrew J. Larson, Garrett W. Meigs, John Paul Roccaforte, Monica T. Rother, Hugh Safford, Michael Schaedel, Jason S. Sibold, Megan P. Singleton, Alexandra K. Urza, Kyra D. Clark-Wolf, Monica G. Turner Mar 2023

Reduced Fire Severity Offers Near-Term Buffer To Climate-Driven Declines In Conifer Resilience Across The Western United States, Kimberley T. Davis, Marcos D. Robles, Kerry B. Kemp, Philip E. Higuera, Teresa Chapman, Kerry L. Metlen, Jamie L. Peeler, Kyle C. Rodman, Travis Woolley, Robert N. Addington, Brian J. Buma, Alina C. Cansler, Michael J. Case, Brandon M. Collins, Jonathan D. Coop, Solomon Z. Dobrowski, Nathan S. Gill, Collin Haffey, Lucas B. Harris, Brian J. Harvey, Ryan D. Haugo, Matthew D. Hurteau, Dominik Kulakowski, Caitlin E. Littlefield, Lisa A. Mccauley, Nicholas Povak, Kristen L. Shive, Edward Smith, Jens T. Stevens, Camille S. Stevens-Rumann, Alan H. Taylor, Alan J. Tepley, Derek J.N. Young, Robert A. Andrus, Mike A. Battaglia, Julia K. Berkey, Sebastian U. Busby, Amanda R. Carlson, Marin E. Chambers, Erich Kyle Dodson, Daniel Donato, William M. Downing, Paula J. Fornwalt, Joshua S. Halofsky, Ashley Hoffman, Andrés Holz, Jose M. Iniguez, Meg A. Krawchuk, Mark R. Krieder, Andrew J. Larson, Garrett W. Meigs, John Paul Roccaforte, Monica T. Rother, Hugh Safford, Michael Schaedel, Jason S. Sibold, Megan P. Singleton, Alexandra K. Urza, Kyra D. Clark-Wolf, Monica G. Turner

Geography

Increasing fire severity and warmer, drier postfire conditions are making forests in the western United States (West) vulnerable to ecological transformation. Yet, the relative importance of and interactions between these drivers of forest change remain unresolved, particularly over upcoming decades. Here, we assess how the interactive impacts of changing climate and wildfire activity influenced conifer regeneration after 334 wildfires, using a dataset of postfire conifer regeneration from 10,230 field plots. Our findings highlight declining regeneration capacity across the West over the past four decades for the eight dominant conifer species studied. Postfire regeneration is sensitive to high-severity fire, which limits …

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Historical Anthropogenic Disturbances Explain Long-Term Moorland Vegetation Dynamics, Francis Rowney, Ralph M. Fyfe, Leonard Baker, Henry French, Martha B. Koot, Havananda Ombashi, Rhys G. O. Timms Mar 2023

Historical Anthropogenic Disturbances Explain Long-Term Moorland Vegetation Dynamics, Francis Rowney, Ralph M. Fyfe, Leonard Baker, Henry French, Martha B. Koot, Havananda Ombashi, Rhys G. O. Timms

School of Geography, Earth and Environmental Sciences

Upland moorlands are important landscapes, but many are considered degraded as a result of human activities. Consequently, their protection and restoration are of substantial concern. In Europe, restoration activities are often aimed at reversing the effects of 19th and 20th century “agricultural improvements,” which often involved major drainage schemes. However, the ecological effects and long-term ecological context of “agricultural improvement” are not yet fully understood. To develop this understanding, we analyze paleoecological data (pollen, coprophilous fungal spores, microcharcoal) from five upland peatland sites using a range of analytical approaches: cluster analysis, principal component analysis, rate-of-change analysis, and regression analyses incorporating …

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March 8, 2023, Faculty, Illinois Wesleyan University Mar 2023

March 8, 2023, Faculty, Illinois Wesleyan University

2022-2023

No abstract provided.

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Evidence For A Causal Role For Escherichia Coli Strains Identified As Adherent-Invasive (Aiec) In Intestinal Inflammation, Hatem Kittana, Joao Carlos Gomes-Neto, Kari Heck, Anthony Juritsch, Jason Sughroue, Yibo Xian, Sara Mantz, Rafael R. Segura Muñoz, Liz Cody, Robert J. Schmaltz, Christopher L. Anderson, Rodney A. Moxley, Jesse M. Hostetter, Samodha C. Fernando, Jennifer Clarke, Stephen D. Kachman, Clayton E. Cressler, Andrew K. Benson, Jens Walter Mar 2023

Evidence For A Causal Role For Escherichia Coli Strains Identified As Adherent-Invasive (Aiec) In Intestinal Inflammation, Hatem Kittana, Joao Carlos Gomes-Neto, Kari Heck, Anthony Juritsch, Jason Sughroue, Yibo Xian, Sara Mantz, Rafael R. Segura Muñoz, Liz Cody, Robert J. Schmaltz, Christopher L. Anderson, Rodney A. Moxley, Jesse M. Hostetter, Samodha C. Fernando, Jennifer Clarke, Stephen D. Kachman, Clayton E. Cressler, Andrew K. Benson, Jens Walter

Department of Nutrition and Health Sciences: Faculty Publications

Enrichment of adherent-invasive Escherichia coli (AIEC) has been consistently detected in subsets of inflammatory bowel disease (IBD) patients. Although some AIEC strains cause colitis in animal models, these studies did not systematically compare AIEC with non-AIEC strains, and causal links between AIEC and disease are still disputed. Specifically, it remains unclear whether AIEC shows enhanced pathogenicity compared to that of commensal E. coli found in the same ecological microhabitat and if the in vitro phenotypes used to classify strains as AIEC are pathologically relevant. Here, we utilized in vitro phenotyping and a murine model of intestinal inflammation to systematically compare …

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Critical Perspectives To Advance Educational Equity And Health Justice, Yael Cannon, Nicole Tuchinda Mar 2023

Critical Perspectives To Advance Educational Equity And Health Justice, Yael Cannon, Nicole Tuchinda

Georgetown Law Faculty Publications and Other Works

A robust body of research supports the centrality of K-12 education to health and well-being. Critical perspectives, particularly Critical Race Theory (CRT) and Dis/ability Critical Race Studies (DisCrit), can deepen and widen health justice’s exploration of how and why a range of educational inequities drive health disparities. The CRT approaches of counternarrative storytelling, race consciousness, intersectionality, and praxis can help scholars, researchers, policymakers, and advocates understand the disparate negative health impacts of education law and policy on students of color, students with disabilities, and those with intersecting identities. Critical perspectives focus upon and strengthen the necessary exploration of how structural …

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Using Music And Storytelling As Strategies For Conservation Education, Frances Hincks Mar 2023

Using Music And Storytelling As Strategies For Conservation Education, Frances Hincks

Honors College Theses

Given the frequently negative effects each person imposes on their environment (e.g., resource consumption, use of private and public land, and waste production), the public needs to be included in conservation messaging to sustain a healthy, functioning planet. People are generally not informed about conservation topics, which creates difficulties in creating a conservation mindset. Moreover, there is a disconnect between conservation research and presenting conservation related topics to the public in a coherent, accessible format. Thus, conservation education messaging strategies need to be evaluated to determine which are most effective. The objective of this research was to determine the effectiveness …

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A New, Extremely Sensitive, Turn-Off Optical Sensor Utilizing Schiff Base For Fast Detection Of Cu(Ii), Lotfi M Aroua, Reham Ali, Abuzar E A E Albadri, Sabri Messaoudi, Fahad M Alminderej, Sayed M Saleh Mar 2023

A New, Extremely Sensitive, Turn-Off Optical Sensor Utilizing Schiff Base For Fast Detection Of Cu(Ii), Lotfi M Aroua, Reham Ali, Abuzar E A E Albadri, Sabri Messaoudi, Fahad M Alminderej, Sayed M Saleh

Faculty, Staff and Student Publications

Throughout this research, a unique optical sensor for detecting one of the most dangerous heavy metal ions, Cu(II), was designed and developed. The (4-mercaptophenyl) iminomethylphenyl naphthalenyl carbamate (MNC) sensor probe was effectively prepared. The Schiff base of the sensor shows a "turn-off" state with excellent sensitivity to Cu(II) ions. This innovative fluorescent chemosensor possesses distinctive optical features with a substantial Stocks shift (about 114 nm). In addition, MNC has remarkable selectivity for Cu(II) relative to other cations. Density functional theory (DFT) and the time-dependent DFT (TDDFT) theoretical calculations were performed to examine Cu(II) chelation structures and associated electronic properties in …

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Applications And Clinical Trial Landscape Using Toll-Like Receptor Agonists To Reduce The Toll Of Cancer, Christian Rolfo, Elisa Giovannetti, Pablo Martinez, Shannon Mccue, Aung Naing Mar 2023

Applications And Clinical Trial Landscape Using Toll-Like Receptor Agonists To Reduce The Toll Of Cancer, Christian Rolfo, Elisa Giovannetti, Pablo Martinez, Shannon Mccue, Aung Naing

Faculty, Staff and Student Publications

Toll-like receptors (TLRs), which serve as a bridge between innate and adaptive immunity, may be viable treatment targets. TLRs are the first line of defense against microbes and activate signaling cascades that induce immune and inflammatory responses. Patients with "hot" versus "cold" tumors may respond more favorably to immune checkpoint inhibition, and through their downstream effects, TLR agonists have the potential to convert "cold tumors" into "hot tumors" making TLRs in combination with immune checkpoint inhibitors, potential targets for cancer therapies. Imiquimod is a topical TLR7 agonist, approved by the FDA for antiviral and skin cancer treatments. Other TLR adjuvants …

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Neuronal Sirt3 Deletion Predisposes To Female-Specific Alterations In Cellular Metabolism, Memory, And Network Excitability, Jennifer N Pearson-Smith, Ruth Fulton, Christopher Q Huynh, Anna G Figueroa, Gia B Huynh, Li-Ping Liang, Lindsey B Gano, Cole R Michel, Nichole Reisdorph, Richard Reisdorph, Kristofer S Fritz, Eric Verdin, Manisha Patel Mar 2023

Neuronal Sirt3 Deletion Predisposes To Female-Specific Alterations In Cellular Metabolism, Memory, And Network Excitability, Jennifer N Pearson-Smith, Ruth Fulton, Christopher Q Huynh, Anna G Figueroa, Gia B Huynh, Li-Ping Liang, Lindsey B Gano, Cole R Michel, Nichole Reisdorph, Richard Reisdorph, Kristofer S Fritz, Eric Verdin, Manisha Patel

Faculty, Staff and Students Publications

Mitochondrial dysfunction is an early event in the pathogenesis of neurologic disorders and aging. Sirtuin 3 (SIRT3) regulates mitochondrial function in response to the cellular environment through the reversible deacetylation of proteins involved in metabolism and reactive oxygen species detoxification. As the primary mitochondrial deacetylase, germline, or peripheral tissue-specific deletion of SIRT3 produces mitochondrial hyperacetylation and the accelerated development of age-related diseases. Given the unique metabolic demands of neurons, the role of SIRT3 in the brain is only beginning to emerge. Using mass spectrometry-based acetylomics, high-resolution respirometry, video-EEG, and cognition testing, we report targeted deletion of SIRT3 from select neurons …

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Medicalization Of Sex In The Cold War, Adelaide Vergnolle Mar 2023

Medicalization Of Sex In The Cold War, Adelaide Vergnolle

Historical Perspectives: Santa Clara University Undergraduate Journal of History, Series II

No abstract provided.

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Swapping Supers: Analyzing Gender Swapped Superheroes In American Comic Books, Damian Fong Mar 2023

Swapping Supers: Analyzing Gender Swapped Superheroes In American Comic Books, Damian Fong

Historical Perspectives: Santa Clara University Undergraduate Journal of History, Series II

No abstract provided.

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Strengthening Achievement, Behavior, And Culture With Social, Emotional, And Academic Learning, Joelle Hood, Janeen Antonelli Mar 2023

Strengthening Achievement, Behavior, And Culture With Social, Emotional, And Academic Learning, Joelle Hood, Janeen Antonelli

National Youth Advocacy & Resilience Conference

Social and emotional skills are foundational for success in school, the workplace, and life. Research also supports that if we want SEL to be successful and sustainable with students, then it must start with the adults. In this engaging session, participants will explore the research supporting Social, Emotional, and Academic Learning (SEAL), as well as how to infuse SEAL into their daily teaching practices.

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Effect On Sward Botanical Composition Of Mixed And Sequential Grazing By Cattle And Sheep Of Upland Permanent Pasture In The Uk, J. E. Vale, M. D. Fraser, J. G. Evans Mar 2023

Effect On Sward Botanical Composition Of Mixed And Sequential Grazing By Cattle And Sheep Of Upland Permanent Pasture In The Uk, J. E. Vale, M. D. Fraser, J. G. Evans

IGC Proceedings (1977-2023)

Previous work has shown benefits of sequential grazing by cattle and sheep, with superior liveweight gains being recorded for lambs grazing swards previously grazed by cattle. A preliminary study of the effects of mixed sheep and cattle grazing also suggested that more extensively grazed swards offer scope for complementary grazing between sheep and cattle. The aim of this experiment was to directly compare these two approaches of integrating the grazing of cattle and sheep.

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Effect Of Mixed And Sequential Grazing By Cattle And Sheep Of Upland Permanent Pasture On Liveweight Gain, M. D. Fraser, J. E. Vale, J. G. Evans Mar 2023

Effect Of Mixed And Sequential Grazing By Cattle And Sheep Of Upland Permanent Pasture On Liveweight Gain, M. D. Fraser, J. E. Vale, J. G. Evans

IGC Proceedings (1977-2023)

Previous work has shown benefits of sequential grazing by cattle and sheep, with superior liveweight gains being recorded for lambs grazing swards previously grazed by cattle. A preliminary study of the effects of mixed sheep and cattle grazing also suggested that more extensively grazed swards offer scope for complementary grazing between sheep and cattle. The aim of this experiment was to directly compare these two approaches of integrating the grazing of cattle and sheep.

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Effects Of Breed And Stage Of Growing Season On The Metabolic Profile Of Sheep Grazing Moorland, V. J. Theobald, M. D. Fraser, J. M. Moorby Mar 2023

Effects Of Breed And Stage Of Growing Season On The Metabolic Profile Of Sheep Grazing Moorland, V. J. Theobald, M. D. Fraser, J. M. Moorby

IGC Proceedings (1977-2023)

Previous studies have shown that the diet of sheep grazing heather moorland is affected by season (Grant et al., 1987) and the proportion of Calluna vulgaris cover (Osoro et al., 2000). In order to investigate the impact of these factors on the associated nutrient supply of animals grazing heathland, blood samples were taken to monitor the metabolic status of different breeds of sheep at different stages of the growing season when grazing sites with different proportions of heather cover.

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Characterising The Fermentation Capabilities Of Gut Microbial Populations From Different Breeds Of Cattle And Sheep Grazing Heathland, D. R. Davies, M. D. Fraser, V. J. Theobald, E. L. Bakewell Mar 2023

Characterising The Fermentation Capabilities Of Gut Microbial Populations From Different Breeds Of Cattle And Sheep Grazing Heathland, D. R. Davies, M. D. Fraser, V. J. Theobald, E. L. Bakewell

IGC Proceedings (1977-2023)

Previous studies have demonstrated differences in the diet composition of sheep and cattle when grazing heather moorland, and such differences may in turn lead to differences in rumen fermentation characteristics and associated adaptation to diet. To investigate this further an in vitro gas production experiment was conducted using inocula from different breeds of cattle and sheep grazing heathland.

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The Performance Of Cattle On Lowland Species-Rich Neutral Grassland At Three Contrasting Grazing Pressures, B. A. Griffith, J. R.B. Tallowin Mar 2023

The Performance Of Cattle On Lowland Species-Rich Neutral Grassland At Three Contrasting Grazing Pressures, B. A. Griffith, J. R.B. Tallowin

IGC Proceedings (1977-2023)

Grazing is an essential management practice for maintaining the nature conservation value of lowland semi-natural neutral grassland to control succession and create different faunal habitats via structural heterogeneity within the pasture (Duffey et al., 1974). However, there is a paucity of information on what would constitute a sustainable grazing intensity that will deliver the wildlife objectives and what the consequences of this management would be on growth rate of livestock and overall pasture output. An experiment was designed to quantify the ecological and agronomic consequences of imposing different grazing intensities on species-rich neutral grassland. The results will provide sward-based …

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