Digital Commons Network^™

Architecture And New Urbanism’S Relationship To Biomimicry And Floral Design, Alycia Timmerman

Honors Program: Senior Projects (Public)

The craft of floral design is classified as an art and a science. Similarly, architecture is rooted in the two disciplines. After conducting research and exploring biomimicry through the design process, it became evident that the process of design for architecture and floral design are similar. This relationship can also be extended into the field of planning and the New Urbanism movement. This study explores the integration of floral design and biomimicry with architecture and New Urbanism at the scale of the building and city block.

Real-Time Liver Tumor Localization Via Combined Surface Imaging And A Single X-Ray Projection, Hua-Chieh Shao, Yunxiang Li, Jing Wang, Steve Jiang, You Zhang

Faculty, Staff and Student Publications

Objective. Real-time imaging, a building block of real-time adaptive radiotherapy, provides instantaneous knowledge of anatomical motion to drive delivery adaptation to improve patient safety and treatment efficacy. The temporal constraint of real-time imaging (< 500 milliseconds) significantly limits the imaging signals that can be acquired, rendering volumetric imaging and 3D tumor localization extremely challenging. Real-time liver imaging is particularly difficult, compounded by the low soft tissue contrast within the liver. We proposed a deep learning (DL)-based framework (Surf-X-Bio), to track 3D liver tumor motion in real-time from combined optical surface image and a single on-board x-ray projection.

Approach. Surf-X-Bio performs mesh-based deformable registration to track/localize liver tumors volumetrically via three steps. First, a DL model was built to estimate liver boundary motion from an optical surface image, using learnt motion correlations between the respiratory-induced external body surface and liver boundary. Second, the residual liver boundary motion estimation error was further corrected by a graph neural network-based DL model, using information extracted from a …

Longitudinal Ultrasound Imaging And Network Modeling In Rats Reveal Sex-Dependent Suppression Of Liver Regeneration After Resection In Alcoholic Liver Disease, Benjamin K. Barnhart, Toshiki Kan, Ankita Srivastava, Corinne E. Wessner, John Waters, Manju Ambelil, John R. Eisenbrey, Jan B. Hoek, Rajanikanth Vadigepalli

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Liver resection is an important surgical technique in the treatment of cancers and transplantation. We used ultrasound imaging to study the dynamics of liver regeneration following two-thirds partial hepatectomy (PHx) in male and female rats fed via Lieber-deCarli liquid diet protocol of ethanol or isocaloric control or chow for 5–7 weeks. Ethanol-fed male rats did not recover liver volume to the pre-surgery levels over the course of 2 weeks after surgery. By contrast, ethanol-fed female rats as well as controls of both sexes showed normal volume recovery. Contrary to expectations, transient increases in both portal and hepatic artery blood flow …

Length Of Course-Based Undergraduate Research Experiences (Cure) Impacts Student Learning And Attitudinal Outcomes: A Study Of The Malate Dehydrogenase Cures Community (Mcc), Sue Ellen Dechenne-Peters, John Rakus, Amy D. Parente, Tamara L. Mans, Rebecca Eddy, Nicole Galport, Courtney Koletar, Joseph J. Provost, J. Ellis Bell, Jessica K. Bell

Biology: Faculty Publications

Course-based undergraduate research experiences (CUREs) are laboratory courses that integrate broadly relevant problems, discovery, use of the scientific process, collaboration, and iteration to provide more students with research experiences than is possible in individually mentored faculty laboratories. Members of the national Malate dehydrogenase CUREs Community (MCC) investigated the differences in student impacts between traditional laboratory courses (control), a short module CURE within traditional laboratory courses (mCURE), and CUREs lasting the entire course (cCURE). The sample included approximately 1,500 students taught by 22 faculty at 19 institutions. We investigated course structures for elements of a CURE and student outcomes including student …

Mycorrhiza-Mediated Recruitment Of Complete Denitrifying Pseudomonas Reduces N2o Emissions From Soil, Xia Li, Ruotong Zhao, Dandan Li, Guangzhou Wang, Shuikuan Bei, Xiaotang Ju, Ran An, Long Li, Thomas W Kuyper, Peter Christie, Franz S Bender, Ciska Veen, Marcel G A Van Der Heijden, Wim H Van Der Putten, Fusuo Zhang, Klaus Butterbach-Bahl, Junling Zhang

Faculty, Staff and Student Publications

Background: Arbuscular mycorrhizal fungi (AMF) are key soil organisms and their extensive hyphae create a unique hyphosphere associated with microbes actively involved in N cycling. However, the underlying mechanisms how AMF and hyphae-associated microbes may cooperate to influence N2O emissions from "hot spot" residue patches remain unclear. Here we explored the key microbes in the hyphosphere involved in N2O production and consumption using amplicon and shotgun metagenomic sequencing. Chemotaxis, growth and N2O emissions of isolated N2O-reducing bacteria in response to hyphal exudates were tested using in vitro cultures and inoculation experiments.

Results: AMF hyphae reduced denitrification-derived N2O emission (max. 63%) …

Kif3 A Tail Domain Phosphorylation Is Not Required For Ciliogenesis In Mouse Embryonic Fibroblasts, Ayoola Fasawe

Theses and Dissertations

Cilia and flagella are microtubule-based organelles that protrude from the plasma membrane of most cells in the body and play a critical role in cell signaling, motility, and development. Numerous diseases, collectively known as ciliopathies, with phenotypes like developmental abnormalities, cystic kidney disease, and obesity, have been linked to ciliary dysfunction. Intraflagellar transport (IFT) shuttles cellular cargoes along axonemal microtubules and into and out of cilia. IFT is essential for the assembly of cilia and flagella and is powered by heterodimeric kinesin-2 (KIF3A/KIF3B) and dynein-2. While the essential role of kinesin-2 in mammalian ciliogenesis is well established, little is known …

Biased But Reasonable: Bias Under The Cover Of Standard Of Care, Maytal Gilboa

Georgia Law Review

Inequities in the distribution of healthcare are widely acknowledged to plague the United States healthcare system. Controversies as to whether anti-discrimination law allows individuals to bring lawsuits with respect to implicit rather than intentional bias render negligence law an important avenue for redressing harms caused by implicit bias in medical care. Yet, as this Article argues, the focus of negligence law on medical standards of care to define the boundaries of healthcare providers’ legal duty of care prevents the law from adequately deterring implicit bias and leaves patients harmed by biased treatment decisions without redress for their losses, so long …

Engineering T Cells To Suppress Acute Gvhd And Leukemia Relapse After Allogeneic Hematopoietic Stem Cell Transplantation, Feiyan Mo, Norihiro Watanabe, Kayleigh I Omdahl, Phillip M Burkhardt, Xiaoyun Ding, Eiko Hayase, Angela Panoskaltsis-Mortari, Robert R Jenq, Helen E Heslop, Leslie S Kean, Malcolm K Brenner, Victor Tkachev, Maksim Mamonkin

Faculty, Staff and Student Publications

Acute graft-versus-host disease (aGVHD) limits the therapeutic benefit of allogeneic hematopoietic stem cell transplantation (allo-HSCT) and requires immunosuppressive prophylaxis that compromises antitumor and antipathogen immunity. OX40 is a costimulatory receptor upregulated on circulating T cells in aGVHD and plays a central role in driving the expansion of alloreactive T cells. Here, we show that OX40 is also upregulated on T cells infiltrating GVHD target organs in a rhesus macaque model, supporting the hypothesis that targeted ablation of OX40+ T cells will mitigate GVHD pathogenesis. We thus created an OX40-specific cytotoxic receptor that, when expressed on human T cells, enables selective …

Effective Connectivity Of Functional Mri Via Deep Learning Methods, Kai-Cheng Chuang

LSU Doctoral Dissertations

Effective connectivity, based on functional magnetic resonance imaging (fMRI) time series signals, is the quantification of how strongly brain activity in a certain source brain region contributes to brain activity in a target brain region, independent of the contributions of other source regions. Current methods to solve this problem have several limitations. They are either unable to model nonlinear relationships between source and target signals, unable to efficiently quantify time lags in source-target relationships, unable to identify time-varying relationships, or fail to account for variability in the hemodynamic response function that converts neuron activity to a measurable signal. In this …

Cocktail-Party Listening And Cognitive Abilities Show Strong Pleiotropy, Samuel R. Mathias, Emma M. Knowles, Josephine Mollon, Peter T. Fox, Rene L. Olvera, Juan M. Peralta, Satish Kumar, Harald H. H. Goring, Ravi Duggirala, Joanne E. Curran, John Blangero, David C. Glahn

School of Medicine Publications

Introduction: The cocktail-party problem refers to the difficulty listeners face when trying to attend to relevant sounds that are mixed with irrelevant ones. Previous studies have shown that solving these problems relies on perceptual as well as cognitive processes. Previously, we showed that speech-reception thresholds (SRTs) on a cocktail-party listening task were influenced by genetic factors. Here, we estimated the degree to which these genetic factors overlapped with those influencing cognitive abilities.

Methods: We measured SRTs and hearing thresholds (HTs) in 493 listeners, who ranged in age from 18 to 91 years old. The same individuals completed a cognitive test …

“I’Ve Got Out At Last”: The Subversion Of Hegemonic Masculinity In Charlotte Perkins Gilman’S “The Yellow Wallpaper”, Ahmad Qabaha, Bilal Hamamra

An-Najah University Journal for Research - B (Humanities)

Drawing on Raewyn Connell’s concept “hegemonic masculinity” and engaging the critical line of feminism, this article argues that Gilman’s “The Yellow Wallpaper” unearths the institutional dynamics that sustain the masculine hegemonic discourse. This article reads this short story as counter-hegemony, the narrator of which critiques what Gramsci called “manufacture of consent”, wherein ideas and beliefs are shaped, and hegemony is reproduced, through culture. We argue that Gilman accounts for the ways in which gender hierarchy is maintained through consent rather than force, and she endorses a struggle over ideas and beliefs to create counter-hegemony that contests socially-constructed dominant ideas and …

An Ecosystem Modelling Approach To Rehabilitating Semi-Desert Rangelands Of North Horr, Kenya, G. A. Olukoye, W. N. Wamicha, J. I. Kinyamario

IGC Proceedings (1977-2023)

Decreased rainfall, recurrent droughts and increased anthropogenic activities have led to a dramatic increase in wind erosion on pastoral lands of North Horr resulting in the reactivation of the once-stable sand dunes. This has degraded the vegetation and impoverished the local community. Mobile sand has a severe impact on dry season grazing areas (Omar & Abdal, 1994) and, therefore, affects pastoral livestock production. In North Horr, Suaeda monoica is important in camel production and for stabilising sand dunes but it has been over-utilized over the years. The objective of this study was to use ecosystem modelling approaches to examine the …

Riparian Management In Intensive Grazing Systems For Improved Biodiversity And Environmental Quality: Productive Grazing, Healthy Rivers, S. R. Aarons, M. Jones-Lennon, P. Papas, N. Ainsworth, F. Ede, J. Davies

IGC Proceedings (1977-2023)

Within high rainfall intensive grazing systems of southern Victoria, riparian zones are often degraded due to vegetation clearing, stock access and inappropriate farm management. Streams in these landscapes often have poor water quality and reduced biodiversity due to degraded terrestrial and aquatic ecosystems. Improved management of riparian zones depends on developing tools and practices for integration into productive grazing systems. This paper describes the approaches used and the tools developed in the ‘Productive Grazing, Healthy Rivers: Improving riparian and in-stream biodiversity’ project.

Contributions Of The United States Department Of Agriculture Natural Resources Conservation Service To Conserving Grasslands On Private Lands In The United States, L. Peter Heard

IGC Proceedings (1977-2023)

The future of biodiversity in the USA is tied inseparably to activities taking place on private lands. Agriculture is by far the most important user of these lands, with about 50% or 900M acres managed as private cropland, grassland or rangeland. Decisions made by America’s farmers and ranchers directly affect grasslands and their impact on food supply, biodiversity, soil protection and water quality. Agricultural programs and policies in the USA have had a large influence on the choices available to farmers and ranchers in land management. Since the 1930s, USDA’s Natural Resource Conservation Service (NRCS) has been working with farmers, …

Effects Of Disturbance And Conspecific Negative Density Dependence On Forest Composition And Diversity: A Simulation-Based Approach, David M. Chan, Benjamin S. Ramage, Matthew E. Mills

Spora: A Journal of Biomathematics

Forests provide a wide range of services to humans and create critical habitat for countless species. Tree species composition and diversity, key attributes of forest health and identity, are influenced by both disturbance and conspecific negative density dependence (CNDD). These factors have been thoroughly researched in isolation, but much less is known about how they interact. We present results of a simulation model constructed to investigate the interactions of variable CNDD strengths and disturbance types. We found that while CNDD consistently increased diversity, the magnitude of this effect was heavily influenced by the disturbance regime. The difference between weak and …

Novel Polymorphs Of Voxelotor And Their Processes For Preparation Thereof, Msn Laboratories Private Limited, R&D Center; Srinivasan Thirumalai Rajan; Sajja Eswaraiah; Vijayavitthal T. Mathad; Saladi Venkata Narasayya And Kammari Balraju.

Defensive Publications Series

The present invention relates to novel polymorphs of Voxelotor of formula-1, which is represented by the following structural formula-1 and process for preparation thereof.

Formula-1.

Faculty Handbook Section Iii - College Of Liberal Arts Policies And Procedures - Updated 3/8/2023, All Faculty

Faculty Handbooks

No abstract provided.

Theoretical Framework For The Study Of Genetic Diseases Caused By Dominant Alleles, Michael Roberts, Stephen Bricher

Articles, Essays, & Creative Writing

We propose a theoretical basis for analyzing several features of genetic diseases caused by dominant alleles, including: disease prevalence, genotype penetrance, and the relationship between causal genotype frequency and disease frequency. In addition, we provide a theoretical framework for accurate diagnosis and clinical approaches for disease study, including two examples in which inaccurate and incomplete diagnoses affect the estimates of disease prevalence: First, the disease iceberg effect shows that disease prevalence is often underestimated due to errors introduced by inaccurate diagnosis; second, because lifetime risk of disease is cumulative, and therefore an increasing function of age, measurements of prevalence are …

Lack Of Counseling Services Among Adults Aged 50 And Greater, Madalyn Olson

Counselor Education Capstones

The geriatric population is increasing every year which may indicate a rising need for retirement and mental health counseling. It is essential for individuals aging out of the workforce to prepare for a life after work and know how to create a new identity. Counselors need to be aware of the different scales and assessments that are available to help determine one’s attitude towards retirement and willingness to seek counseling to prepare for retirement. Additionally, it is important to be aware that although there are counseling services available for mental health disorders and substance use disorders, these services are limited …

Committee On Academic Standing Minutes March 8, 2023, Bronx Community College Committee On Academic Standing

BCC Governance Archives

Minutes for the meeting of the Committee on Academic Standing on March 8, 2023.

Past, Present, And A Glance Into The Future Of Multiple Myeloma Treatment., Weam Othman Elbezanti, Kishore B Challagundla, Subash C. Jonnalagadda, Tulin Budak-Alpdogan, Manoj K Pandey

College of Science & Mathematics Departmental Research

Multiple myeloma (MM) is a challenging hematological cancer which typically grows in bone marrow. MM accounts for 10% of hematological malignancies and 1.8% of cancers. The recent treatment strategies have significantly improved progression-free survival for MM patients in the last decade; however, a relapse for most MM patients is inevitable. In this review we discuss current treatment, important pathways for proliferation, survival, immune suppression, and resistance that could be targeted for future treatments.

Insight - Spring 2023, Dugoni School Of Dentistry

Insight

Welcome to the spring 2023 issue of Insight, a newsletter celebrating the accomplishments of our community of scholars. We aim to spotlight insights from people at the Dugoni School working in all areas of scholarship, including clinical or biomedical research, the scholarship of teaching and learning, improvement of the health care system, and professional partnerships that advance the field.

The Earliest Dipodomyine Heteromyid In North America And The Phylogenetic Relationships Of Geomorph Rodents, Joshua X. Samuels, Jonathan J.-M. Calede, Robert M. Hunt Jr.

Department of Earth and Atmospheric Sciences: Faculty Publications

Dipodomyine heteromyids (kangaroo rats and mice) are a diverse group of aridadapted ricochetal rodents of North America. Here, a new genus and species of a large dipodomyine is reported from early Miocene-aged deposits of the John Day Formation in Oregon that represents the earliest record of the subfamily. The taxon is known from a single specimen consisting of a nearly complete skull, dentary, partial pes, and caudal vertebra. The specimen is characterized by a mosaic of ancestral and highly derived cranial features of heteromyids. Specifically, the dental morphology and some cranial characteristics are similar to early heteromyids, but other aspects …

Second Language Acquiescence Of Multilingual Students In Tanzania, Ann E. Roemer

World Languages and Cultures Faculty Publications

This research, conducted at a major university in Tanzania, investigated the personal experiences of multilingual students vis-à-vis the government's language policy requiring Swahili as the language of instruction (LoI) at the primary level and English at the secondary level. The participants, who spoke 25 different languages as their L1, were placed into 49 different language groups and asked to write what they remembered about the language policy where they attended school. The data show that Gramsci's cultural hegemony is occurring in Tanzania. The 'common sense' is that people truly believe English is symbolic of prestige and power–even though few people …

Whole Transcriptome-Based Skin Virome Profiling In Typical Epidermodysplasia Verruciformis Reveals Α-, Β-, And Γ-Hpv Infections, Amir Hossein Saeidian, Leila Youssefian, Mahtab Naji, Hamidreza Mahmoudi, Samantha M Barnada, Charles Huang, Karim Naghipoor, Amir Hozhabrpour, Jason S Park, Flavia Manzo Margiotta, Fatemeh Vahidnezhad, Zahra Saffarian, Kambiz Kamyab-Hesari, Mohammad Tolouei, Niloofar Faraji, Seyyede Zeinab Azimi, Ghazal Namdari, Parvin Mansouri, Jean-Laurent Casanova, Vivien Béziat, Emmanuelle Jouanguy, Jouni Uitto, Hassan Vahidnezhad

Department of Dermatology and Cutaneous Biology Faculty Papers

HPVs are DNA viruses include approximately 450 types that are classified into 5 genera (α-, β-, γ-, μ-, and ν-HPV). The γ- and β-HPVs are present in low copy numbers in healthy individuals; however, in patients with an inborn error of immunity, certain species of β-HPVs can cause epidermodysplasia verruciformis (EV), manifesting as recalcitrant cutaneous warts and skin cancer. EV presents as either typical or atypical. Manifestations of typical EV are limited to the skin and are caused by abnormal keratinocyte-intrinsic immunity to β-HPVs due to pathogenic sequence variants in TMC6, TMC8, or CIB1. We applied a transcriptome-based computational pipeline, …

Racism And Social Determinants Of Psychosis, Deidre Anglin

Publications and Research

The Centers for Disease Control and Prevention has identified racism as a serious threat to public health. Structural racism is a fundamental cause of inequity within interconnected institutions and the social environments in which we live and develop. This review illustrates how these ethnoracial inequities impact risk for the extended psychosis phenotype. Black and Latinx populations are more likely than White populations to report psychotic experiences in the United States due to social determining factors such as racial discrimination, food insecurity, and police violence. Unless we dismantle these discriminatory structures, the chronic stress and biological consequences of this race-based stress …

Ic090: Bryant Boutwell Interview, Transcript, Friends Of The Texas Medical Center Library

2023 Oral History Project

See more at Friends of the Texas Medical Center Library Records and its finding aid.

Ic090: Ken Mattox Interview, Transcript, Friends Of The Texas Medical Center Library

2023 Oral History Project

See more at Friends of the Texas Medical Center Library Records and its finding aid.

Black Crowned Night Heron, Kevin Rafferty, Briana K. Zaffiro, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Ycnh 3d Skull, Kevin Rafferty, Briana K. Zaffiro, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.