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Platonism, De Re, And (Philosophy Of) Mathematical Practice, Marco Panza

MPP Published Research

The chapter advances a reformulation of the classical problem of the nature of mathematical objects (if any), here called “Plato’s problem,” in line with the program of a philosophy of mathematical practice. It then provides a sketch of a platonist solution, following the same perspective. This solution disregards as nonsensical the question of the existence of abstract, and specifically mathematical, objects, by rather focusing on the modalities of our access to them: objects (in general, both concrete and abstract) are regarded as individual contents that we have (or can have) a de re epistemic access to. The question of the …

Learning Dynamic Information Of High-Dimensional Signal Time-Series Using Advanced Machine Learning/Artificial Intelligence, Guannan Liu

LSU Doctoral Dissertations

In this dissertation, we propose a novel simulation-based device-free indoor localization and tracking system using the received signal strength indicators (RSSIs) of WiFi signals as the input features. The Feko channel-propagation simulation software is used to process the RSSI maps of the given arbitrary indoor geometry. In order to learn the dynamic information of high-dimensional RSSI time-series, we propose three procedures for the localization and dynamic tracking system.

First, The indoor geometry is partitioned into several equi-size zones and the localization problem is treated as the typical \multi-classification" problem. The advanced machine-learning techniques such as decision tree (DT) classifier, random …

Integrating Cultivar Resistance And Entomopathogens For Pest Management Of Sweetpotato Weevil, Cylas Formicarius Elegantulus (Summers), Schyler M. Lee

LSU Master's Theses

Sweetpotato, Ipomoea batatas (L.) Lam, is the number one vegetable crop in Louisiana, producing 21,178 kg/ha in the year 2021. The sweetpotato weevil, Cylas formicarius elegantulus (Summers), is an economically important pest of sweetpotato. C. formicarius elegantulus females lay eggs into feeding holes on the storage root surface. Larvae then hatch and tunnel through the sweetpotato flesh where they complete their development. This cryptic-natured brentid can cause up to 100% yield loss when left unmanaged. The Louisiana Department of Agriculture and Forestry mandates protocols to limit C. formicarius elegantulus spread (e.g., clean seed, pheromone trapping, and quarantines); however, scheduled chemical …

Full Issue

Insights: The Newsletter of the Neal A. Maxwell Institute for Religious Scholarship

No abstract provided.

Was Mulek A "Blood Son" Of King Zedekiah?, John L. Sorenson

Insights: The Newsletter of the Neal A. Maxwell Institute for Religious Scholarship

The Book of Mormon identifies Mulek as the only son of King Zedekiah to escape execution during the Babylonian siege of Jerusalem (Omni 1:15; Helaman 8:21). Like the Lehites, Mulek and those with him fled Jerusalem and were "brought by the hand of the Lord across the great waters" (Omni 1:16). Descendants of the group later settled in the land of Zarahemla, where the people under Mosiah discovered them and Mosiah became king when the two groups merged into a single polity (Omni 1:19).

Twenty-First Century Colonization Is Not A Good Policy Decision, Ellen Elizabeth Scott

Georgia Journal of International & Comparative Law

No abstract provided.

Lgbtq-Inclusive Sex Education: Lessons The United States Can Learn From The United Kingdom, Nicole D. Katapodis

Georgia Journal of International & Comparative Law

No abstract provided.

Comparative Study Of Multiple Approaches For Identifying Cultivable Microalgae Population Diversity From Freshwater Samples, Amal A. Badr, Walid M. Fouad

Faculty Journal Articles

No abstract provided.

Dataset For: A Coupled Lagrangian-Earth System Model For Predicting Oil Photooxidation, Claire B. Paris, Ana C. Vaz, Robin Faillettaz

C-IMAGE data

The explosion of the Deepwater Horizon (DWH) oil drilling rig on April 20 of 2010 in the Gulf of Mexico resulted in an uncontrolled oil spill from 5000 feet below the sea surface, requiring an extraordinarily rapid response. A decade ago, the technology to model oil spills from the deep ocean did not exist. A few oil models are now capable of forecasting the 3D transport and fate of the oil from such blowout. An important limitation in estimating the fate of the oil is, still today, the lack of spatially explicit photooxidation model parameterization. Weathering of oil near the …

Effects Of Feeding A Vitamin And Mineral Supplement To Cow-Calf Pairs Grazing Native Range, Jennifer L. Hurlbert, Friederike Baumgaertner, Kacie L. Mccathy, Timothy Long, Cody Wieland, Kevin K. Sedivec, Carl R. Dahlen

Department of Animal Science: Faculty Publications

Our objectives were to evaluate the impacts of providing vitamin and mineral (VTM) supplements to cow-calf pairs during the summer grazing period on cow and calf performance and liver concentrations of minerals. During a two-year period, 727 crossbred cows and their calves (initial cow BW = 601.7 ± 48.1 kg; calf BW = 87.8 ± 5.0 kg; n = 381 in year 1, n = 346 in year 2) from the Central Grasslands Research Extension Center (Streeter, N.D.) were blocked by parity (young [parity 1 to 3], and old [parity 4+]) and randomly assigned to pastures at the beginning …

Alma Link Resolver Subject Report 2022-2023, Andrée J. Rathemacher

Technical Services Reports and Statistics

Statistics for 2022-2023 on the number of OpenURL requests by Library of Congress classification code made to the Ex Libris Alma link resolver for items held by the University of Rhode Island Libraries.

Information provided includes Classification Code, Classifications, Number of Requests, Number of Clicked Requests, and % Clicks from Requests.

Alma Link Resolver Title & Issn Report (Top 500) 2022-2023, Andrée J. Rathemacher

Technical Services Reports and Statistics

Statistics for 2022-2023 on the total number of OpenURL requests by journal title and ISSN made to the Ex Libris Alma link resolver for items held by the University of Rhode Island Libraries. Includes only the top 500 journals.

Information provided includes journal Title, ISSN, EISSN, Number of Requests, Number of Clicked Requests, % Clicks from Requests.

Molecular Identification Of Oomycete Species Associated With Woody Plants In Louisiana And Survey Of Oomycete Species Associated With Live Oak Trees Planted On The Louisiana State University Campus, Hamilton Crockett

LSU Master's Theses

Three Oomycetes genera, Phytophthora, Phytopythium and Pythium, contain many important plant pathogens. Historically, Phytophthora infestans, responsible for the great Irish potato famine, and Phytophthora ramorum, causal agent of sudden oak death disease, are the two better-known high impact pathogens. The LSU AgCenter Plant Diagnostic Center (PDC) has been isolating putative Phytophthora and related species from combined root and soil samples collected from various woody ornamentals and trees for over a decade. In August of 2016, Louisiana received torrential rains, which resulted in historic flooding in several southern parishes. During subsequent years, the PDC staff isolated a …

Structural Insights Into Rna Bridging Between Hiv-1 Vif And Antiviral Factor Apobec3g, Takahide Kouno, Satoshi Shibata, Megumi Shigematsu, Jaekyung Hyun, Tae Gyun Kim, Hiroshi Matsuo, Matthias Wolf

Computational Medicine Center Faculty Papers

Great effort has been devoted to discovering the basis of A3G-Vif interaction, the key event of HIV's counteraction mechanism to evade antiviral innate immune response. Here we show reconstitution of the A3G-Vif complex and subsequent A3G ubiquitination in vitro and report the cryo-EM structure of the A3G-Vif complex at 2.8 Å resolution using solubility-enhanced variants of A3G and Vif. We present an atomic model of the A3G-Vif interface, which assembles via known amino acid determinants. This assembly is not achieved by protein-protein interaction alone, but also involves RNA. The cryo-EM structure and in vitro ubiquitination assays identify an adenine/guanine base …

Developmental Pb Exposure Increases Ad Risk Via Altered Intracellular Ca2+ Homeostasis In Hipsc-Derived Cortical Neurons, Junkai Xie, Shichen Wu, Hailey Szadowski, Sehong Min, Yang Yang, Aaron B. Bowman, Jean-Christophe Rochet, Jennifer L. Freeman, Chongli Yuan

Purdue University Libraries Open Access Publishing Fund

Exposure to environmental chemicals such as lead (Pb) during vulnerable developmental periods can result in adverse health outcomes later in life. Human cohort studies have demonstrated associations between developmental Pb exposure and Alzheimer's disease (AD) onset in later life which were further corroborated by findings from animal studies. The molecular pathway linking developmental Pb exposure and increased AD risk, however, remains elusive. In this work, we used human iPSC-derived cortical neurons as a model system to study the effects of Pb exposure on AD-like pathogenesis in human cortical neurons. We exposed neural progenitor cells derived from human iPSC to 0, …

Aotearoa New Zealand, The Forcible Transfer Of Tamariki And Rangatahi Māori, And The Royal Commission On Abuse In Care, David B. Macdonald

Genocide Studies and Prevention: An International Journal

This article investigates to what extent the forcible transfer of tamariki and rangatahi Māori (Indigenous children and youth) in Aotearoa New Zealand can be considered genocide. First, I begin by exploring contemporary genocide theory as it relates to dolus eventualis in settler colonial contexts, before engaging with precedents for recognizing Indigenous genocides established by truth commissions in Canada (2015; 2019) and Australia (1997). I then explore the history around Indigenous child removal in Aotearoa from the onset of colonization to the present day, attentive to ways in which the UN Convention can apply to the forced removal of Māori children. …

Relationships Between Running Biomechanics And Femoral Articular Cartilage Thickness And Composition In Anterior Cruciate Ligament Reconstruction Patients, Hyunwook Lee

Theses and Dissertations

Background: Patients with anterior cruciate ligament reconstruction (ACLR) have demonstrated morphological and compositional changes in femoral articular cartilage. However, it is unclear how running biomechanics are associated with femoral cartilage thickness and composition for both ACLR patients and controls. Objectives: (1) to compare measures of femoral cartilage thickness and composition between ACLR patients and matched non-ACLR controls at resting, (2) to investigate how 30 minutes of running influences the aforementioned measures for ACLR patients and controls, and (3) to investigate relationships between running biomechanics and knee cartilage thickness and composition in ACLR patients and controls. Methods: Twenty ACLR patients (age: …

Scope And Mechanistic Studies On The Ruthenium-Catalyzed Multicomponent Deaminative C–H Coupling Reaction Of Phenols With Aldehydes And Enamines For The Formation Of Xanthene And Dioxacyclic Derivatives, Nuwan Asanka Pannilawithana, Mina Son, Donghun Hwang, Mu-Hyun Baik, Chase S. Yi

Chemistry Faculty Research and Publications

The in situ generated catalytic system from the tetranuclear Ru–H complex [(PCy₃)(CO)RuH]₄(O)(OH)₂ (1) with 3,4,5,6-tetrachloro-1,2-benzoquinone (L1) has been found to mediate a multicomponent deaminative coupling reaction of phenols with aldehydes and enamines to form xanthene products. The multicomponent C–H coupling reaction of phenols with 2-hydroxybenzaldehydes and cyclic enamines efficiently installed the tricyclic 1,3-dioxacin derivatives, while the analogous coupling reaction of phenols with 2-hydroxybenzaldehydes and triethylamine selectively formed bicyclic 1,5-dioxacyclic derivatives. The density functional theory (DFT) calculations established two energetically viable mechanistic pathways for the formation of xanthene products, in which both …

Comutations And Krasg12c Inhibitor Efficacy In Advanced Nsclc, Marcelo V Negrao, Haniel A Araujo, Giuseppe Lamberti, Alissa J Cooper, Neal S Akhave, Teng Zhou, Lukas Delasos, J Kevin Hicks, Mihaela Aldea, Gabriele Minuti, Jacobi Hines, Jacqueline V Aredo, Michael J Dennis, Turja Chakrabarti, Susan C Scott, Paolo Bironzo, Matthias Scheffler, Petros Christopoulos, Albrecht Stenzinger, Jonathan W Riess, So Yeon Kim, Sarah B Goldberg, Mingjia Li, Qi Wang, Yun Qing, Ying Ni, Minh Truong Do, Richard Lee, Biagio Ricciuti, Joao Victor Alessi, Jing Wang, Blerina Resuli, Lorenza Landi, Shu-Chi Tseng, Mizuki Nishino, Subba R Digumarthy, Waree Rinsurongkawong, Vadeerat Rinsurongkawong, Ara A Vaporciyan, George R Blumenschein, Jianjun Zhang, Dwight H Owen, Collin M Blakely, Giannis Mountzios, Catherine A Shu, Christine M Bestvina, Marina Chiara Garassino, Kristen A Marrone, Jhanelle E Gray, Sandip Pravin Patel, Amy L Cummings, Heather A Wakelee, Juergen Wolf, Giorgio Vittorio Scagliotti, Federico Cappuzzo, Fabrice Barlesi, Pradnya D Patil, Leylah Drusbosky, Don L Gibbons, Funda Meric-Bernstam, J Jack Lee, John V Heymach, David S Hong, Rebecca S Heist, Mark M Awad, Ferdinandos Skoulidis

Faculty, Staff and Student Publications

Molecular modifiers of KRASG12C inhibitor (KRASG12Ci) efficacy in advanced KRASG12C-mutant NSCLC are poorly defined. In a large unbiased clinicogenomic analysis of 424 patients with non-small cell lung cancer (NSCLC), we identified and validated coalterations in KEAP1, SMARCA4, and CDKN2A as major independent determinants of inferior clinical outcomes with KRASG12Ci monotherapy. Collectively, comutations in these three tumor suppressor genes segregated patients into distinct prognostic subgroups and captured ∼50% of those with early disease progression (progression-free survival ≤3 months) with KRASG12Ci. Pathway-level integration of less prevalent coalterations in functionally related genes nominated PI3K/AKT/MTOR pathway and additional baseline RAS gene alterations, including amplifications, …

Mitophagy Promotes Resistance To Bh3 Mimetics In Acute Myeloid Leukemia, Christina Glytsou, Xufeng Chen, Emmanouil Zacharioudakis, Wafa Al-Santli, Hua Zhou, Bettina Nadorp, Soobeom Lee, Audrey Lasry, Zhengxi Sun, Dimitrios Papaioannou, Michael Cammer, Kun Wang, Tomasz Zal, Malgorzata Anna Zal, Bing Z Carter, Jo Ishizawa, Raoul Tibes, Aristotelis Tsirigos, Michael Andreeff, Evripidis Gavathiotis, Iannis Aifantis

Faculty, Staff and Student Publications

BH3 mimetics are used as an efficient strategy to induce cell death in several blood malignancies, including acute myeloid leukemia (AML). Venetoclax, a potent BCL-2 antagonist, is used clinically in combination with hypomethylating agents for the treatment of AML. Moreover, MCL1 or dual BCL-2/BCL-xL antagonists are under investigation. Yet, resistance to single or combinatorial BH3-mimetic therapies eventually ensues. Integration of multiple genome-wide CRISPR/Cas9 screens revealed that loss of mitophagy modulators sensitizes AML cells to various BH3 mimetics targeting different BCL-2 family members. One such regulator is MFN2, whose protein levels positively correlate with drug resistance in patients with AML. MFN2 …

Multicultural Orientation-Informed Focused Acceptance And Commitment Therapy For Adolescents Seeking Bariatric Surgery, Mary Elizabeth Keenan-Pfeiffer

Electronic Theses and Dissertations Archive

Objective: The present paper details a pragmatic trial of a Focused Acceptance and Commitment Therapy (FACT) intervention for adolescents seeking bariatric surgery. The intervention was developed within a multicultural orientation (MCO) framework to acknowledge families’ diverse sociocultural contexts and clinical needs. The intervention aimed to increase psychological flexibility, specifically by supporting values-consistent behavior change through openness to internal experiences and present moment awareness, within the context of seeking bariatric surgery. It was designed to be flexibly implemented across two sessions, one focused on increasing adolescent psychological flexibility, the other on increasing caregiver psychological flexibility. The present paper describes implementation and …

List Of 121 Papers Citing One Or More Skin Lesion Image Datasets, Neda Alipour

Other resources

No abstract provided.

Newsroom, Georgia Southern University

Newsroom (2006-2023)

Georgia Southern Professor Featured on National Geographic’s ‘When Sharks Attack 360’; View on Hulu, Disney+ and Nat Geo WILD Throughout July

The Evolution Of Transposable Elements As Cis-Regulatory Elements In Mammals, Alan Y. Du

Arts & Sciences Graduate Student Theses and Dissertations

Transposable elements (TEs) are mobile genetic elements that make up a large proportion of mammalian genomes. Although TEs are highly prevalent genomic sequences, they have been understudied as they were once labeled as “junk DNA.” Despite their initial status as simple genomic parasites, recent studies have implicated TEs as cis-regulatory elements, supplying promoters, enhancers, and boundary elements. Functional testing of regulatory activity, however, remains a significant bottleneck. Nonetheless, due to their repetitive nature, TEs provide a unique model to examine the evolution of cis-regulatory elements, which has traditionally been difficult to study due to lack of homology at the sequence …

Hsc Connects Newsletter - July 7, 2023, Unm Hsc Communications

HSC Connects Newsletters

Weekly newsletter of the UNM Health Sciences Center.

Book Review Of The Nutmeg's Curse: Parables For A Planet In Crisis By Amitav Ghosh, Cynthia Twyford Fowler

Faculty Scholarship

Amitav Ghosh, a celebrated author of fiction and nonfiction, earned a doctorate in social anthropology from Oxford. In this iteration of his nonfiction oeuvre, Ghosh’s mapping of the historical entanglement of human rights abuses and environmental exploitation is framed upon the pillars of postcolonialism and posthumanism. Many of the processes he writes about in his acclaimed book The Nutmeg’s Curse: Parables for a Planet in Crisis overlap with the interests of Human Ecology readers. Chapters 4 “Terraforming,” 5 “We Shall be Gone Shortly,” and 6 “Bonds of Earth” may feel familiar to students of environmental histories and aficionados of Alfred …

Vitamin B2 Enables Regulation Of Fasting Glucose Availability, Peter M Masschelin, Pradip Saha, Scott A Ochsner, Aaron R Cox, Kang Ho Kim, Jessica B Felix, Robert Sharp, Xin Li, Lin Tan, Jun Hyoung Park, Liping Wang, Vasanta Putluri, Philip L Lorenzi, Alli M Nuotio-Antar, Zheng Sun, Benny Abraham Kaipparettu, Nagireddy Putluri, David D Moore, Scott A Summers, Neil J Mckenna, Sean M Hartig

Faculty, Staff and Students Publications

Flavin adenine dinucleotide (FAD) interacts with flavoproteins to mediate oxidation-reduction reactions required for cellular energy demands. Not surprisingly, mutations that alter FAD binding to flavoproteins cause rare inborn errors of metabolism (IEMs) that disrupt liver function and render fasting intolerance, hepatic steatosis, and lipodystrophy. In our study, depleting FAD pools in mice with a vitamin B2-deficient diet (B2D) caused phenotypes associated with organic acidemias and other IEMs, including reduced body weight, hypoglycemia, and fatty liver disease. Integrated discovery approaches revealed B2D tempered fasting activation of target genes for the nuclear receptor PPARα, including those required for gluconeogenesis. We also found …

Endothelial Cell Cd36 Regulates Membrane Ceramide Formation, Exosome Fatty Acid Transfer And Circulating Fatty Acid Levels, V S Peche, T A Pietka, M Jacome-Sosa, D Samovski, H Palacios, G Chatterjee-Basu, A C Dudley, W Beatty, G A Meyer, I J Goldberg, N A Abumrad

2020-Current year OA Pubs

Endothelial cell (EC) CD36 controls tissue fatty acid (FA) uptake. Here we examine how ECs transfer FAs. FA interaction with apical membrane CD36 induces Src phosphorylation of caveolin-1 tyrosine-14 (Cav-1Y14) and ceramide generation in caveolae. Ensuing fission of caveolae yields vesicles containing FAs, CD36 and ceramide that are secreted basolaterally as small (80-100 nm) exosome-like extracellular vesicles (sEVs). We visualize in transwells EC transfer of FAs in sEVs to underlying myotubes. In mice with EC-expression of the exosome marker emeraldGFP-CD63, muscle fibers accumulate circulating FAs in emGFP-labeled puncta. The FA-sEV pathway is mapped through its suppression by CD36 depletion, blocking …

Evaluation Of A Nutritional Calming Supplement For Stress Management In Beef Cattle, Randall Mallette

LSU Master's Theses

Two studies were conducted to determine the efficacy of two formulations of a nutritional calming product, Placid 1.0 and Placid 2.0, at keeping beef cattle in a calm state when exposed to environmental factors that put them into an excited state. In the pilot study, nine crossbred beef heifers were orally drenched daily for three days with 60 mL of their respective treatments, pen scores and exit scores were recorded, and blood was collected for cortisol analysis. There were no treatment effects for either treatment on any of the measured behavioral parameters or serum cortisol concentrations.

The products were …

Effect Of Total Population, Population Density And Weighted Population Density On The Spread Of Covid-19 In Malaysia, Hui Shan Wong, Md Zobaer Hasan, Omar Sharif, Azizur Rahman

School of Mathematical & Statistical Sciences Faculty Publications

Since November 2019, most countries across the globe have suffered from the disastrous consequences of the Covid-19 pandemic which redefined every aspect of human life. Given the inevitable spread and transmission of the virus, it is critical to acknowledge the factors that catalyse transmission of the disease. This research investigates the relation of the external demographic parameters such as total population, population density and weighted population density on the spread of Covid-19 in Malaysia. Pearson correlation and simple linear regression were utilized to identify the relation between the population-related variables and the spread of Covid-19 in Malaysia using data from …