Digital Commons Network^™

B. R. Wells Arkansas Rice Research Studies 2022, J. Hardke, X. Sha, N. Bateman

Arkansas Agricultural Experiment Station Research Series

Arkansas is the leading rice producer in the United States. The state represents 50.1% of total U.S. rice production and 49.8% of the total acres planted to rice in 2022. Rice cultural practices vary across the state and across the U.S. However, these practices are also dynamic and continue to evolve in response to changing political, environmental, and economic times. This survey was initiated in 2002 to monitor and record changes in the way Arkansas rice producers approach their livelihood. The survey was conducted by polling county extension agents in each of the counties in Arkansas that produce rice. Questions …

Human Microbiome Variation Associated With Race And Ethnicity Emerges As Early As 3 Months Of Age, Elizabeth K. Mallott, Alexandra R. Sitarik, Leslie D. Leve, Camille Cioffi, Carlos A. Camargo, Kohei Hasegawa, Seth R. Bordenstein

Public Health Sciences Articles

Human microbiome variation is linked to the incidence, prevalence, and mortality of many diseases and associates with race and ethnicity in the United States. However, the age at which microbiome variability emerges between these groups remains a central gap in knowledge. Here, we identify that gut microbiome variation associated with race and ethnicity arises after 3 months of age and persists through childhood. One-third of the bacterial taxa that vary across caregiver-identified racial categories in children are taxa reported to also vary between adults. Machine learning modeling of childhood microbiomes from 8 cohort studies (2,756 samples from 729 children) distinguishes …

Examining Sociodemographic Correlates Of Opioid Use, Misuse, And Use Disorders In The All Of Us Research Program, Hsueh-Han Yeh, Cathryn Peltz-Rauchman, Christine C. Johnson, Pamala A. Pawloski, David Chesla, Stephen C. Waring, Alan B. Stevens, Mara Epstein, Christine Lm Joseph, Lisa R. Miller-Matero, Hongsheng Gui, Amy Tang, Eric Boerwinkle, Mine Cicek, Cheryl R. Clark, Elizabeth Cohn, Kelly Gebo, Roxana Loperena, Kelsey Mayo, Stephen Mockrin, Lucila Ohno-Machado, Sheri Schully, Andrea H. Ramirez, Jun Qian, Brian K. Ahmedani

Center for Health Policy and Health Services Research Articles

BACKGROUND: The All of Us Research Program enrolls diverse US participants which provide a unique opportunity to better understand the problem of opioid use. This study aims to estimate the prevalence of opioid use and its association with sociodemographic characteristics from survey data and electronic health record (EHR).

METHODS: A total of 214,206 participants were included in this study who competed survey modules and shared EHR data. Adjusted logistic regressions were used to explore the associations between sociodemographic characteristics and opioid use.

RESULTS: The lifetime prevalence of street opioids was 4%, and the nonmedical use of prescription opioids was 9%. …

Reducing Cognitive Arousal And Sleep Effort Alleviates Insomnia And Depression In Pregnant Women With Dsm-5 Insomnia Disorder Treated With A Mindfulness Sleep Program, David A. Kalmbach, Philip Cheng, Anthony N. Reffi, Jason C. Ong, Leslie M. Swanson, Colin A. Espie, Grace M. Seymour, Mika Hirata, Olivia Walch, D'Angela S. Pitts, Thomas Roth, Christopher L. Drake

Sleep Medicine Articles

OBJECTIVES: Combining mindfulness with behavioral sleep strategies has been found to alleviate symptoms of insomnia and depression during pregnancy, but mechanisms for this treatment approach remain unclear. The present study examined nocturnal cognitive arousal and sleep effort as potential treatment mechanisms for alleviating insomnia and depression via a mindfulness sleep program for pregnant women.

METHODS: Secondary analysis from a proof-of-concept trial of 12 pregnant women with DSM-5 insomnia disorder who were treated with Perinatal Understanding of Mindful Awareness for Sleep (PUMAS), which places behavioral sleep strategies within a mindfulness framework. Data were collected across eight weekly assessments: pretreatment, six sessions, …

Studying The Stability Of Collagen/Heparin Coatings To Be Used In Cell Therapy Applications, Gavin Mussino

Biological Sciences Undergraduate Honors Theses

This honors thesis aims to investigate the reusability and performance of cell coatings for cell therapy applications. Cell therapy, which involves the use of human cells to repair or replace damaged tissues, holds immense potential for medical advancements. However, ensuring the survival and functionality of transplanted cells remains a significant challenge. We focused on studying the effectiveness of coatings applied to cells for improved cell growth and viability. The research project involved the preparation of the coatings using a layer-by-layer method and the subsequent seeding of cells. The coated cells were then subjected to a series of experiments to assess …

Anything But Bland: Uncovering The Hidden Diversity And Genomic Origin Of The Threatened Vanilla Spice, Paige Ellestad

Boise State University Theses and Dissertations

Conserving the genetic diversity of crop species and their wild relatives has become a mounting concern as the detrimental effects of climate change, habitat destruction, and genetic erosion are being realized. In this epoch of unprecedented biodiversity loss, the genetic resources needed to improve crops may be at risk of extinction. Even one of the most iconic spices, vanilla, is threatened. Wild populations of the main vanilla producing species, Vanilla planifolia Andrews (Orchidaceae), are being rapidly extirpated due to deforestation and illegal harvesting in their native range. On top of that, clonal propagation methods within cultivated plants are hypothesized to …

Using Terrestrial Laser Scanning To Estimate Canopy Structure In Peatland Conifers Under A Climate Manipulation, Angela D. Seibert

Boise State University Theses and Dissertations

Northern peatlands are major terrestrial carbon sinks, storing 415 ± 150 Gt of carbon. The composition of peatland vegetation affects this carbon storage capacity, and thus quantifying the vegetation helps to constrain uncertainty in peatland carbon storage estimates. Ground layer vegetation, such as Sphagnum sp. moss contributes greatly to carbon storage capacity. In forested peatlands, the tree canopy structure directly influences peatland solar insolation, soil temperature, and water table levels. Each of these factors impacts the ground layer vegetation. Currently, there is uncertainty about how the peatland tree canopy structure is influenced by elevated levels of carbon dioxide (CO_{2 …}

Probing The Mechanism Of Dna Protein Crosslink Formation By Aziridinomitosenes Through The Selective Precipitation Of Protein Salts, Michael Blair

Boise State University Theses and Dissertations

Aziridinomitosenes are synthetic chemotherapeutic agents that are analogs of Mitomycin C, as well as other mitomycins. They are known for their ability to form DNA interstrand cross-links (ICLs), and more recently have been observed to form DNA-protein cross-links (DPCs). In this work, three synthetic aziridinomitsenes were prepared and studied to better understand the role of the C6 and C7 positions in the formation of DNA-protein cross-links. In addition, two separate methods, the advanced recovery of K-SDS precipitates and the K-SDS assays were utilized and compared to assess the advancements in the analysis of DPC formation. H AZM, C6 AZM, Dimethyl …

Dietary Effects On Cardiac Lipid Composition And Subsequent Phenotype In The American Lobster (Homarus Americanus), Melissa Colette Butler

All Theses And Dissertations

Lipids are fundamental components of many biological structures and compositions of these molecular species can alter with diet. Differences in lipid membrane composition can impact the functioning of membranes and proteins subsequently altering the organism’s ability to respond to stressful conditions. American lobsters (Homarus americanus) are an economically important shellfish in New England and are sometimes kept intermittently in lobster impoundments (pounds) for months where they are often fed herring, which differs from the assumed natural diet of wild-caught lobsters. In this study, we compared the lipid composition of lobsters obtained from the wild and pounds that were …

Group B Streptococcus: A New Perspective, Susan Harris

MSN Capstone Projects

Group B streptococcus (GBS) is a major cause of illness and death in young infants across the nation. Current guidelines suggest pregnant women should be screened from thirty-five-to- thirty-seven-weeks gestation. Although screening may be negative at that time, the expectant mother could become colonized with GBS before delivery. GBS is a pathogen that lives in the gastrointestinal and genitourinary tract of fifteen to twenty percent of women of childbearing age (Moorhead et al., 2019). GBS does not become a problem until it is passed from colonized mothers to the neonate during delivery (Virranniemi et al., 2019). When GBS is passed …

Visual Circuitry In Adaptive Behavior: Extraction Of Complex Visual Image Information By Arrays Of Non-Image Forming Eyes, Thomas Kipp Halladay Groves

Dissertations

A complete understanding of how neural circuitry underlies the detection and integration of visual cues continues to elude researchers in the 21st century. Since the dawn of life on earth, light has exerted enormous selective pressure on all living organisms. Visual systems represent one of the most common sensory systems in existence, with significant homologies among elements of these systems, such as photopigments and developmental genes. Offering nearly unmatched single cell access at all levels of its nervous system, the European medicinal leech (Hirudo spp.) is an excellent system in which to identify behaviorally relevant neuronal circuits. Hirudo evolved discrete …

Conflict: An Autoethnography On Anthropology And Conflict Management, Rachel Koch

Boise State University Theses and Dissertations

Anthropology has many goals, such as understanding our evolutionary origins, distinctiveness as a species, and vast diversity of social existence worldwide and through time. The current study looks at the feasibility of combining the theoretical and applied methods of anthropology and conflict resolution to help future anthropologists do better anthropology. I created an interdisciplinary mixed methods study to gauge the compatibility and possibility of integration. Recruiting participants from a conflict management course on having difficult conversations, pre- and post-discussion surveys were given to measure how well narrative inquiry can help those on differing sides of a difficult conversation understand one …

Poly(Alkyl Aldehyde)S: A New Class Of Closed-Loop Recyclable Plastics, Kyle Arnold Nogales

Boise State University Theses and Dissertations

This dissertation will describe a new class of closed-loop recyclable, self-immolative polymers that undergo selective, complete, and rapid depolymerization in the solid state when triggered. Self-immolative poly(alkyl aldehyde)s are synthesized efficiently in approximately 60% yield using anionic polymerization, which provides access to polymers in accessible lengths ranging from short (M_n value of 2 kDa) to long polymers (M_n value of 5,000 kDa). The physical and thermal properties of the polymers can be tuned rationally by appropriate choice of the aldehyde monomer, with some of the polymers displaying mechanical properties that are similar to traditional plastics. The polymers depolymerize …

Analysis Of Emerging Constituents In An Activated Sludge Treatment Facility, Abigail Mae Sigurdson Ryan

Boise State University Theses and Dissertations

Emerging constituents (ECs), or contaminants of emerging concern (CECs), are pharmaceuticals and personal care products (Contaminants of Emerging Concern including Pharmaceuticals and Personal Care Products | US EPA, 2023). The primary source of ECs in surface waters is the discharge from wastewater treatment facilities (WWTF) (Kumar et al., 2022). Little is known about the effects treatment processes have on ECs. Research regarding ECs has increased due to the threats they pose to the environment and human health (Khan et al., 2021). This research aimed to expand understanding ECs’ fate through an activated sludge WWTF. This was accomplished by studying concentrations …

Investigating The Causes Of A Landslide In Terra Nativa Subdivision And Designing Slope Stabilization Using Recycled Plastic Pins, Clara Klamm

Boise State University Theses and Dissertations

In early 2016, five homes along Alto Via Court in the Terra Nativa Subdivision of the Boise Foothills began to move. By May of 2016, the street was closed due to safety concerns, and a few years later, the homes were demolished. Despite the heartbreak and legal action that followed the event, a definitive cause of the landslide was never identified. To date, the site remains vacant. This research aims to investigate the potential causes of the slide to help identify the contributing factors that resulted in the mishap. In addition, the research seeks to design a way to stabilize …

The Effects Of Socioeconomic Status On Female Health At St. Benet Sherehog, Anastasia S. Slack

Boise State University Theses and Dissertations

This research investigates the impacts of socioeconomic status on female health at three pre-industrial burial sites in London, England. The analysis compares the female skeletal sample from the parish burial of St. Benet Sherehog (SB), a high-status site, to the cemeteries at the ‘New Churchyard’ at Broadgate (BG) and St. Thomas Hospital (ST), both representing low-status sites during the 17th century. Data for St. Thomas Hospital was made available by the Museum of London’s Wellcome Osteological Research Database and was compared with published data for St. Benet Sherehog and Broadgate to test the hypothesis that women at St. Benet Sherehog …

Study Of Dry Mixing Method To Apply Microbial-Induced Calcite Precipitation For Soil Treatment, Ruchi Shrestha

Boise State University Theses and Dissertations

Microbially Induced Calcite Precipitation (MICP) has emerged as a promising technique for soil stabilization, traditionally involving the preparation and mixing of treatment solutions with the soil. However, this thesis explores a novel approach of applying MICP by directly mixing dry chemical compounds into the soil and subsequently adding water. This alternative method offers potential advantages in terms of convenience, ease of implementation, and cost savings.

The objective of this research is to investigate the applicability of dry mixing protocols for MICP in soil stabilization. Through comprehensive experimentation, three different dry protocols were developed and applied to five different soils. The …

Integrating Sensor Development, Risk Assessment, And Community Engagement To Support Environmental Justice In The Rural Community Of El Tiple, Colombia, David Bahamon Pinzon

All Dissertations

In Colombia, ethnic communities have traditionally been responsible stewards of natural resources. They recognize the importance of these resources for their livelihood, as well as their ancestral and cultural heritage. El Tiple, a rural Afro-Colombian community, has been affected by the incursion of private corporations that promoted the expansion of sugarcane monocrops in their territory. Since the introduction of the monoculture industry, local freshwater sources have been depleted due to intensive water use for irrigation of the sugarcane crops. Additionally, the intensive usage of agrochemicals has been linked with loss of native flora, damages to family farms, and pollution of …

Apheresis Collection Of Mononuclear Cells For Chimeric-Antigen Receptor Therapies, Robert W. Maitta

Faculty Scholarship

Collections of lymphocytes to be genetically modified to treat hematologic malignancies have seen a dramatic increase over the last few years as commercial products have been approved. Reports of new products in development that can possibly treat solid organ malignancies represent a massive change in the field. Apheresis is at the center of the collection of cells for the manufacture of these chimeric-antigen receptor therapy products. The expansion of these collections represents one of the areas of apheresis procedures growth. This review will summarize concepts important to this type of collection and variables that need to be optimized to obtain …

Demodex Blepharitis: A Comprehensive Review Of The Disease, Current Management, And Emerging Therapies, Michelle K. Rhee, Elizabeth Yeu, Melissa Barnett, Christopher J. Rapuano, Deepinder K Dhaliwal, Kelly K. Nichols, Paul Karpecki, Francis S. Mah, Arthur Chan, James Mun, Ian Benjamin Gaddie

Wills Eye Hospital Papers

Demodex blepharitis is a common disease of the eyelid, affecting approximately 25 million Americans. This article reviews what is known about the mechanisms and impact of Demodex blepharitis, risk factors, signs and symptoms, diagnostic techniques, current management options, and emerging treatments. Demodex mites contribute to blepharitis in several ways: direct mechanical damage, as a vector for bacteria, and by inducing hypersensitivity and inflammation. Risk factors for Demodex blepharitis include increasing age, rosacea, and diabetes. The costs, symptom burden, and psychosocial effects of Demodex blepharitis are considerable. The presence of collarettes is pathognomonic for Demodex blepharitis. Redness, dryness, discomfort, foreign body …

Columns Fall 2023, Southern Adventist University

Alumni Newsletter

Features information about Southern Adventist University's archeological museum, enrollment growth, Homecoming, and the annual Alumni Association Tour.

Knowledge Representation And Management 2022: Findings In Ontology Development And Applications, Jean Charlet, Licong Cui, Section Editors For The Imia Yearbook Section On Knowledge Representation And Management

Faculty, Staff and Student Publications

OBJECTIVES: To select, present, and summarize the best papers in 2022 for the Knowledge Representation and Management (KRM) section of the International Medical Informatics Association (IMIA) Yearbook.

METHODS: We conducted PubMed queries and followed the IMIA Yearbook guidelines for performing biomedical informatics literature review to select the best papers in KRM published in 2022.

RESULTS: We retrieved 1,847 publications from PubMed. We nominated 15 candidate best papers, and two of them were finally selected as the best papers in the KRM section. The topics covered by the candidate papers include ontology and knowledge graph creation, ontology applications, ontology quality assurance, …

Exogenous Exposure To Dihydroxyacetone Mimics High Fructose Induced Oxidative Stress And Mitochondrial Dysfunction, Raj Mehta

Honors Theses

Dihydroxyacetone (DHA) is a three-carbon sugar that is the active ingredient in sunless tanning products and a by-product of electronic cigarette (e-cigarette) combustion. Increased use of sunless tanning products and e-cigarettes has elevated exposures to DHA through inhalation and absorption. Studies have confirmed that DHA is rapidly absorbed into cells and can enter into metabolic pathways following phosphorylation to dihydroxyacetone phosphate (DHAP), a product of fructose metabolism. Recent reports have suggested metabolic imbalance and cellular stress results from DHA exposures. However, the impact of elevated exposure to DHA on human health is currently under-investigated. We propose that exogenous exposures to …

Discovery Of Ojt009 As A Novel Inhibitor Of Severe Acute Respiratory Syndrome Coronavirus 2 Infection For Potential Treatment Of C0vid-19, Tolulope Olayinka Adebusuyi

Dissertations (2016-Present)

The emergence of deadly SARS-CoV-2 variants with mutations in the viral genes has made it more imperative to discover therapeutics that target the host receptors for coronavirus disease (COVID-19) treatment. SARS-CoV-2 spike protein receptor-binding domain (RBD) binds to host ACE2 receptor, facilitating viral entry (Jackson, 2022). The Interaction between ACE2 and the RBD region of Spike protein is the most crucial step in the viral life cycle. Therefore, the ACE2- RBD interaction has remained a key target for therapeutics in COVID19 treatment. Therefore, our research has targeted this interaction to prevent SARS-CoV-2 entry into the human cells. ACE2, a key …

Mate Choice And Sexual Conflict In A Livebearing Fish, Julia C. Kasper

Master's Theses

Eavesdropping occurs when a receiver extracts information from an interaction without directly engaging with the signaler. Eavesdropping has been shown to be an effective way of evaluating the quality of potential mates and their abilities in male-male competition, without having to directly interact with them, thereby reducing energy costs and mating harassment. Girardinus metallicus is a livebearing poeciliid fish endemic to Cuba whose mating system is dominated by mating harassment in the form of sneak copulations, persistent displaying, and male-male aggression. G. metallicus has a male specific polymorphism in both melanin coloration and behavior. Males with melanin coloration are known …

Phase Distribution Of Nickel, Chromium, And Cobalt In Seawater At Olivine-Enriched Beaches: Implications For Carbon Capture By Enhanced Silicate Weathering, Nathaniel J. Padrnos

Master's Theses

The application of olivine to coastal areas is a proposed method of removing carbon dioxide from the atmosphere for climate change mitigation. Olivine is abundant and dissolves relatively fast, but it contains trace amounts of nickel (Ni), chromium (Cr), and cobalt (Co) which may be toxic to marine biota in cases of widespread coastal olivine spreading. Prior studies have suggested that Ni concentrations in marine sediments and/or the overlying water column due to olivine dissolution could be a limiting factor for its carbon capture potential. Therefore, it is critical to understand and model the processes affecting trace metal bioavailability after …

Functional Exploration Of Conserved Sequences In The Distal Face Of Angiotensinogen - Brief Report, Naofumi Amioka, Chia-Hua Wu, Hisashi Sawada, Sohei Ito, Alex C. Pettey, Congqing Wu, Jessica J. Moorleghen, Deborah A. Howatt, Gregory A. Graf, Craig W. Vander Kooi, Alan Daugherty, Hong S. Lu

Saha Cardiovascular Research Center Faculty Publications

BACKGROUND: Angiotensinogen (AGT) is an essential component in the renin-angiotensin system. AGT has highly conserved sequences in the loop and β-sheet regions among species; however, their functions have not been studied.

METHODS: Adeno-associated viral vector (AAV) serotype 2/8 encoding mouse AGT with mutations of conserved sequences in the loop (AAV.loop-Mut), β-sheet (AAV.βsheet-Mut), or both regions (AAV.loop/βsheet-Mut) was injected into male hepatocyte-specific AGT-deficient (hepAGT−/− ) mice in an LDL (low-density lipoprotein) receptor–deficient background. AAV containing mouse wild-type AGT (AAV.mAGT) or a null vector (AAV.null) were used as controls. Two weeks after AAV administration, all mice were fed a western diet for …

A Mixed Methods Analysis Of Influences Surrounding Undergraduate Science Recruitment: Identifying Challenges And Opportunities, Evelyn Abagayle Boyd

All Dissertations

Often prevalent in the sciences, undergraduate research experiences (UREs) are highly beneficial engaged learning experiences in higher education. Though the benefits of UREs are well established, there is little information about which students participate in these experiences and the pathways they take to become engaged in them. This study consists of three works which surround the overarching research question: How do undergraduate science students initialize research experiences such that departments and institutions can improve access to these high-impact practices? Utilizing the intersection of the theories of Science Capital and Social Cognitive Career Theory, this study provides insight and recommendations into …

Functional Analysis Of Two Campoletis Sonorensis Ichnovirus Vinnexins In Drosophila Melanogaster, Peng Zhang

All Dissertations

Campoletis sonorensis Ichnovirus (CsIV) is produced by the ichneumonid parasitoid Campoletis sonorensis (the primary host). Female parasitoid wasps restrictedly replicate viruses in their ovaries and inject them into a larval lepidopteran (secondary host) during oviposition. This symbiotic virus of C. sonorensis is essential for successful parasitization. CsIV is characterized by having a large, segmented double-stranded DNA genome with a large number of genes, many of which are associated with one of five multigene families. The CsIV vinnexin gene family is one of them and has four members, including CsIV-vnxD and CsIV-vnxG. Vinnexins are homologues of insect Innexins, which form gap …

Lunchbox Hydroponics, Stacy A. Adams

Department of Agronomy and Horticulture: Faculty Publications

Growing plants with hydroponics is less complicated than it may appear when the fundamentals of the system are understood. This publication provides instruction on the construction of a simple hydroponic prototype suitable for school or youth education programs. The fundamentals of hydroponics, basic design of a solution system, seed starting, creating a nutrient solution, and plant care are explored through this engaging project. This prototype can successfully be used to grow small edible and herb plants in the classroom or at home.