Digital Commons Network^™

A Predictive Flood Model For Urban Karst Groundwater Systems, Trayson Lawler

Masters Theses & Specialist Projects

Urban karst environments are often plagued by groundwater flooding, which occurs when water rises from the subsurface to the surface through the underlying caves and other karst features. The heterogeneity and interconnectedness of karst systems often makes them very unpredictable, especially during intense storm events; urbanization exacerbates the problem with the addition of many impervious surfaces. Residents in such areas are frequently disturbed and financially burdened by the effects of karst groundwater flooding. The Federal Emergency Management Agency (FEMA) offers limited protection to citizens living near flood-prone areas as they primarily focus on the areas near surface bodies of water. …

A Comparison Of Computational Perfusion Imaging Techniques, Shaharina Shoha

Masters Theses & Specialist Projects

Dynamic contrast agent magnetic resonance perfusion imaging plays a vital role in various medical applications, including tumor grading, distinguishing between tumor types, guiding procedures, and evaluating treatment efficacy. Extracting essential biological parameters, such as cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT), from acquired imaging data is crucial for making critical treatment decisions. However, the accuracy of these parameters can be compromised by the inherent noise and artifacts present in the source images.

This thesis focuses on addressing the challenges associated with parameter estimation in dynamic contrast agent magnetic resonance perfusion imaging. Specifically, we aim …

Utilizing Show Cave Tours To Assess Nonformal Karst Education Outcomes In Youth, Matthew Wisenden

Masters Theses & Specialist Projects

Karst landscapes are regions with geological features such as caves created by the dissolution of predominantly carbonate bedrock. The aesthetic, historical, and ecological significance of karst areas results in human modification of some caves to allow public visitation as ‘show caves.’ While show caves can experience higher levels of anthropogenic degradation than non-commercialized caves, they can also be integral to regional economic, societal, and environmental wellbeing. Moreover, show caves serve as primary platforms for disseminating karst education. School fieldtrips to show caves offer a unique setting for assessing karst-related environmental learning outcomes in children through a nonformal education setting. By …

How Gender Roles Impact The Social Perceptions Of Sexual Assault, Autumn Zwakenberg

Masters Theses & Specialist Projects

This study set out to examine how different factors such as the gender of the victim, the gender of the perpetrator, and the scenario of sexual assault, can influence an outsider’s opinion of the sexual assault. There were two main hypotheses: the first is male and female participants would perceive the push-away scenario as sexual assault at equal rates, but significantly more female participants would perceive the victim allowing the perpetrator to unbuckle their pants scenario as sexual assault. The second is male and female participants would view the male perpetrator scenarios as sexual assault equally, but significantly more female …

Associations Between Parenting Styles & Parental Self-Efficacy, Brian Richards

Masters Theses & Specialist Projects

The purpose of this study was to examine whether there is an association between parenting styles and parental self-efficacy using a United States sample. One hundred twentytwo parents with at least one child between the ages of 5 and 12 years were recruited for the study. Participants were asked to complete a survey with measures for parenting styles and parental self-efficacy as well as demographic information. Results indicated that authoritative parenting style was positively correlated with parental self-efficacy; while authoritarian, permissive, and uninvolved styles were negatively correlated. There is a need to replicate these findings to increase confidence that the …

A Phylogenetic Analysis Of The Leuctra Ferruginea (Walker 1852) Species Group (Plecoptera: Leuctridae), Madison Layer

Masters Theses & Specialist Projects

Leuctra Stephens, 1836 is a genus of Plecoptera (Leuctridae) distributed widely across the Northern Hemisphere, with approximately 210 species reported from eastern North America, Europe, northern Africa, and sporadically across Asia. Eastern North America harbors a small proportion of the global Leuctra fauna (ca. 15% = 31 species), most of which occur in the ancient Appalachian Mountains and unglaciated landscapes in the southeastern USA. Nearctic Leuctra species, except for L. moha and L. crossi, have been divided into five species groups based on external male morphological characteristics. Current phylogenies of Nearctic Leuctra are partial and preliminary, and no comprehensive …

Assessing The Effect Of Reservoirs On Gene Flow In The Southern Two-Lined Salamander (Eurycea Cirrigera), Anna Favalon

Masters Theses & Specialist Projects

Biodiversity is an essential component of natural environmental dynamics. Unfortunately, diversity is threatened by human activities and relies on conservation efforts. An important aspect of biodiversity conservation lies in protecting population connectivity and gene flow. In the mid-1900s, many Kentucky rivers were dammed, creating deep, lentic reservoirs in the valleys once occupied by dynamic, lotic rivers. For species inhabiting the rivers and associated tributaries, the central reservoirs may reduce connectivity among populations and impose a barrier to gene flow. The connectivity of populations on landscapes altered by the creation of reservoirs can be assessed by merging the principles of landscape …

College For What . . . How Middle School Students From Low Socioeconomic Backgrounds Perceived Post-Secondary Education, Michelle Patrick

Dissertations

This study examines the attitudes and perceptions of middle school students from low socioeconomic backgrounds about attending post-secondary institutions. As research continues to explore the experiences of traditional high school students from low socioeconomic backgrounds and students' attendance into post-secondary institutions, research concerning middle school students from low socioeconomic backgrounds preparedness for college attendance has been limited. Using a phenomenological research design to obtain the study's results from fifteen students and thirteen parent interviews provided insight into the “lived experience” of the students’ and parents' attitudes and perceptions regarding college attendance. The study found that regardless of the parents’ and …

Enhancing Adherence To Best Practice Guidelines Related To Pressure Injury Prevention In The Operating Room At A Children's Hospital During Comprehensive Dental Procedures., Alyce Bailey Seaver

Doctor of Nursing Practice Papers

Background: 1,600,000 patients develop a hospital-acquired pressure injury every year, and 23% of these originate during surgery. Research has demonstrated that the incidence of hospital-acquired pressure injuries developing during surgery has risen over the past 5 years. This rise has been attributed to nurse circulators exhibiting poor knowledge regarding best practices for intraoperative patient positioning and intraoperative documentation that does not follow standards of care.

Purpose: This quality improvement project aimed to enhance circulator knowledge on best practices for intraoperative patient positioning and improve documentation of intraoperative patient positioning in the electronic medical record to comply with standards of …

Workload Assessment For Community Corrections Staffing For The Washington Department Of Corrections, Nathan Lowe, Adam K. Matz, Benjamin Korelitz, Angela Greene, Kathryb Hogan

Criminal Justice Faculty Publications

About 20 years ago, the Washington State Department of Corrections (WADOC) participated in two workload evaluations with the aim of identifying key tasks associated with community corrections work and the time to complete such tasks, and utilized these data to inform the amount of resources needed to carry out the responsibilities of the Community Corrections Division (CCD). Those evaluations set a precedent for how WADOC made informed decisions that shaped practice and policy for staffing. Then, in the fall of 2021, WADOC contracted with Westat, Inc. to conduct an updated, full-scale workload assessment of staff members who carry out the …

Stochastic Processes And Multi-Resolution Analysis: A Trigonometric Moment Problem Approach And An Analysis Of The Expenditure Trends For Diabetic Patients, Isaac Nwi-Mozu

Computational and Data Sciences (PhD) Dissertations

This dissertation is divided into two distinct parts. The main theme of the first part is to study stochastic processes (and related signal processing questions) using tools in wavelet analysis, functional analysis (we use in particular the trigonometric moment problem), the theory of realization of rational functions, and reproducing kernel Hilbert spaces. A novel form of multiresolution analysis is formulated in the discrete case that is used to study some stochastic processes. Using the trigonometric moment problem, we associate with a vector-valued wide-sense stationary process a multiresolution of a new kind. The notion of realization of rational functions was used …

2023 Fall - Schedule Of Classes, Office Of The Registrar, East Tennessee State University

Registration Resources

No abstract provided.

Dinitroxides In Rapid Scan Electron Paramagnetic Resonance Imaging, Lukas B. Woodcock

Electronic Theses and Dissertations

Local tissue physiology is an important parameter in understanding disease behavior. Rapid Scan (RS) electron paramagnetic resonance (EPR) offers a unique, non-invasive tool for investigation of these so-called microenvironments through EPR Imaging (EPRI). Research into advancement of EPRI falls into many categories. Not least among those are advances in instrumentation and methodology. Presented here are updates to a benchtop EPRI instrument operating at 1 GHz targeted at pre-clinical EPRI applications. Newly developed methods for reducing RS-EPR background through inversion of the magnetic field are also demonstrated. EPR applications are limited in native biological systems due to the miniscule concentration of …

An Existential Punchline: How Humor Functions In A Young Adult Friendship Facing Advanced Cancer, Megan E. Solberg

Electronic Theses and Dissertations

Young adults (i.e., age 18-39) only comprise 4% of the total cancer population, yet cancers in this group are commonly found at more advanced stages due to situational factors influencing delayed diagnosis including access to healthcare, quality health insurance and competing life demands that may hinder prioritization of healthcare. Young adults with cancer also face unique challenges including higher rates of psychological distress, which may contribute to increased risk of social disconnection in response to cancer. Research suggests that humor may be a helpful coping approach and communication mechanism for mitigating distress and discussing difficult topics. Grounded within the frameworks …

Laryngeal Symptoms Related To Motor Phenotypes In Parkinson's Disease: A Systematic Review, Zoë Thijs Ph.D., Matthew Dumican

Communication Sciences and Disorders: Faculty Publications

Objective This study aimed to systematically review the associations between motor clinical phenotypes in Parkinson's disease (PD) and laryngeal disease symptoms. Laryngeal dysfunctions such as dysphonia and dysphagia are ubiquitous in people with Parkinson's disease (PwPD). Similar to other disease symptoms, they manifest variably across PwPD. Some of the variability within PD has been explained by clinical phenotypes. However, it is unclear how laryngeal symptoms of PD express themselves across these phenotypes.

Methods Five databases were searched (MEDLINE, CINAHL, Web of Science, Embase, Scopus) in May 2022. After the removal of duplicates, all retrieved records were screened. Cohort, case–control, and …

The Words. Or Holes. Or Both: Writing As An Integrative Methodology For Trauma, Daniel A. Castle

Electronic Theses and Dissertations

This project seeks to identify methods authors have used to integrate their traumatic experiences. My work will analyze the genre of War Literature and specific authors like J.R.R. Tolkien and Kurt Vonnegut to explore the way writers describe the trauma of combat. Using insights from neuroscience and psychology, I will expand the field of Cognitive Literary Studies from a focus on the reader to a focus on the writer by linking neurological functions with narrative tools.

Hemodynamic Assessment Of Y-Incision Aortic Root Enlargement Using Computational Simulations, Astitwa Ghimire

Electronic Theses and Dissertations

The Yang procedure is a new aortic root enlargement technique used to enlarge the aortic annulus by multiple valve sizes. The procedure prevents patient prosthesis mismatch and establishes a viable platform for future valve-in-valve implantation. This study used the Yang procedure to investigate the hemodynamics in the aortic root and bioprosthetic valve regions after aortic root enlargement. Results indicate the velocity magnitude at the sinus regions of a patient who underwent the Yang procedure was slower, indicating risks of flow stasis and thrombosis. Simulation results denote computational models can be created for optimization of surgical procedures.

Mechanisms Behind The Chaperone Activity Of Nucleic Acids, Theodore J. Litberg

Electronic Theses and Dissertations

Understanding the interplay between nucleic acids and protein aggregation is integral to the understanding of proteostasis, aging, and neurodegenerative disease progression. Nucleic acids are known to modulate the aggregation of PrP, tau, ⍺-synuclein, and other disease relevant proteins. Although the interactions between misfolded protein and nucleic acids can play a role in disease, this interaction may potentially be beneficial as well. Our group and others have shown nucleic acids can be powerful chaperones. Previous work has shown both RNA and DNA can prevent protein aggregation and RNA can pass off protein clients to the heat shock protein (Hsp) system. Here …

Queer Interethnic Relationships: Couple-Level Minority Stress And Resilience For Intersectionally Marginalized Partners, Sree Sinha

Electronic Theses and Dissertations

Interethnic relationships and same-sex relationships continue to increase in the U.S. While LGBQ and heterosexual people are equally likely to be in romantic relationships, LGBQ individuals are more likely than their straight peers to be in an interracial or interethnic romantic relationship. The present work aims to expand intersectional investigations regarding queer people of color (QPOC), including accounting for their individual as well as relational well-being, by use of the couple-level minority stress (CLMS) paradigm. CLMS theory speaks to the unique stressors experienced as a result of being in a relationship that is societally marginalized, impacting both dyadic and individual …

Do-It-Together: Informal Transformative Sustainability Education, Derek Brannon

Electronic Theses and Dissertations

The Climate Crisis is an urgent and inescapable reality students are thrust into. Learners must be prepared adequately for their futures, not only for their sakes but also because collective and transformative change is required. Transformative sustainability education provides one pathway to this transformation and focuses on radically altering students’ perceptions about the world and their agency in effecting change on ecological issues. The field of transformative sustainability education is emergent and thus is still fragmented, leaving gaps in the literature. Little research has been conducted on how informal and nonformal university spaces can be used to create transformative experiences …

Hydrological Dynamics Of Surface-Groundwater Interactions Between Major Springs Of Mammoth Cave And The Green River, Kentucky, Usa, Matthew Cecil

Masters Theses & Specialist Projects

Mammoth Cave is an iconic example of the cave and karst systems that underlie over 50% of the United States and provide around 13% of the world’s population with water resources. These environmental features are vulnerable to drought, pollution, and human impacts. The complex hydrological regime of the Mammoth Cave system has been studied in the past, but there are improvements and updates that can be made to the past research. The dynamics of the surface-groundwater system, particularly reversals of the Green River and how it backfloods into the cave, are some examples. Echo River and River Styx Springs provide …

Biomarkers In Borrelia Burgdorferi Infected Triple-Negative Breast Cancer Cells, Sambuddha Paul

Master's Theses

Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited treatment options and a poor prognosis. Although some studies have attempted to identify new biomarkers and therapies, only a few have shown promise in clinical trials. In the context of cancer development, infectious agents rank as the third major risk factor, contributing to approximately 15-20% of cancer cases, according to the American Cancer Society. Hence, the identification of biomarkers associated with infection-originated cancer is crucial for enhancing cancer prevention, early detection, diagnosis, and treatment. Borrelia burgdorferi, the causative agent of Lyme disease, has been linked to TNBC …

Identification Of Structural Brain Alterations In Adolescents With Depressive Symptomatology, J. Bashford‑Largo, R. James R. Blair, Karina S. Blair, Matthew Dobbertin, Ahria Dominguez, Melissa Hatch, Sahil Bajaj

Center for Brain, Biology, and Behavior: Faculty Publications

Introduction: Depressive symptoms can emerge as early as childhood and may lead to adverse situations in adulthood. Studies have examined structural brain alternations in individuals with depressive symptoms, but findings remain inconclusive. Furthermore, previous studies have focused on adults or used a categorical approach to assess depression. The current study looks to identify grey matter volumes (GMV) that predict depressive symptomatology across a clinically concerning sample of adolescents.

Methods: Structural MRI data were collected from 338 clinically concerning adolescents (mean age = 15.30 SD=2.07; mean IQ = 101.01 SD=12.43; 132 F). Depression symptoms were indexed via the Mood …

Building Teachers’ Capacity To Implement Equitable Family, School, And Community Partnerships Through School Psychologists’ Consultation: The Partnership Capacity Building Consultation Model And Case Study, Bryanna S. Fatigate

Electronic Theses and Dissertations

The urgency to prioritize equity-driven policies is amplified by the disproportionate education and health outcomes that emerged during the COVID-19 pandemic. Eradicating inequity demands the prioritization of robust family, school, and community partnerships (FSCP). For decades, research has highlighted the benefits of FSCP, which may include improvements in student academic achievement, behavior, ratings of school climate, and attendance; furthermore, FSCP is associated with higher guardian involvement, mentor opportunities, career development, and a reduced need for more intensive services such as special education (Adelman & Taylor, 2015; Anderson- Butcher & Anderson, 2018; Constantino, 2016). To reap the benefits of such partnerships, …

Activation Of The Renin–Angiotensin–Aldosterone System Is Attenuated In Hypertensive Compared With Normotensive Pregnancy, Robin C. Shoemaker, Marko Poglitsch, Hong Huang, Katherine Vignes, Aarthi Srinivasan, Cynthia Cockerham-Morris, Aric Schadler, John Anthony Bauer, John O'Brien

UK CARES Faculty Publications

Hypertension during pregnancy increases the risk of adverse maternal and fetal outcomes, but the mechanisms of pregnancy hypertension are not precisely understood. Elevated plasma renin activity and aldosterone concentrations play an important role in the normal physiologic adaptation to pregnancy. These effectors are reduced in patients with pregnancy hypertension, creating an opportunity to define the features of the renin–angiotensin–aldosterone system (RAAS) that are characteristic of this disorder. In the current study, we used a novel LC-MS/MS-based methodology to develop comprehensive profiles of RAAS peptides and effectors over gestation in a cohort of 74 pregnant women followed prospectively for the development …

Modeling Biphasic, Non-Sigmoidal Dose-Response Relationships: Comparison Of Brain- Cousens And Cedergreen Models For A Biochemical Dataset, Venkat D. Abbaraju, Tamaraty L. Robinson, Brian P. Weiser

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Biphasic, non-sigmoidal dose-response relationships are frequently observed in biochemistry and pharmacology, but they are not always analyzed with appropriate statistical methods. Here, we examine curve fitting methods for “hormetic” dose-response relationships where low and high doses of an effector produce opposite responses. We provide the full dataset used for modeling, and we provide the code for analyzing the dataset in SAS using two established mathematical models of hormesis, the Brain-Cousens model and the Cedergreen model. We show how to obtain and interpret curve parameters such as the ED50 that arise from modeling, and we discuss how curve parameters might change …

Spring 2023 General Education Assessment Report, Lindenwood University

General Education Assessment

Spring 2023 General Education Assessment Report.

Characterization Of Legionella Pneumophila Effector Proteins, Lneb And Mava, Kayode Adeyemi

Masters Theses & Specialist Projects

The crucial virulence factor of accidental human pathogen Legionella pneumophila during the course of Legionnaire disease is the over 300 effector proteins secreted from its Dot/Icm secretion system. Eukaryotic host cells usually elicit an arsenal of immune responses against invading L. pneumophila. Nonetheless, the bacteria unexpectedly subvert these defense mechanisms to survive and proliferate unhindered in the host. Although some effector proteins have been proposed to play a significant role in this host-pathogen interaction, many still need to be characterized. The LneB and MavA proteins are examples of those effectors that need characterization. Thus, this study aimed to investigate the …

Mammalian & Avian Community Response To African Elephant (Loxodonta Africana) Habitat Modification In Southeastern Kenya, Dakota Vaccaro

Masters Theses & Specialist Projects

African elephants (Loxodonta africana) play a significant role in the modification of their habitat, foremost by decreasing woody vegetation cover and density and in some parts of Africa high elephant densities damage small sanctuaries and preserves. For wildlife that depend on forested patches, this increased modification could lead to displacement and/or decreases in abundance. If suitable habitat is not available elsewhere, elephants and other wildlife may move closer to humans in search of resources, which can result in increased human-wildlife conflict. Evaluating this impact was one of the goals of the Elephants and Sustainable Agriculture in Kenya (ESAK) …

Teacher Perceptions Of Advanced Ability English Language Learners (Ell), Dena Redmond

Masters Theses & Specialist Projects

This study explored teacher perceptions of English language learners and giftedness. High school content teachers participated in an interview identifying behaviors that indicate advanced abilities from a series of three vignettes about English language learners. A total of four participants were interviewed. The four emergent themes were (1) critical thinking (2) rate of language acquisition, (3) motivation, and (4) use of language. The themes were behaviors that teachers perceived as demonstrating potential or demonstrating limited potential for advanced learning in English language learners.