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Articles 10681 - 10710 of 35286
Full-Text Articles in Entire DC Network
Mosca Linterna Moteada, Lori R. Spears, Ann Mull, Celina Wille, Marion Murray
Mosca Linterna Moteada, Lori R. Spears, Ann Mull, Celina Wille, Marion Murray
All Current Publications
La mosca linterna moteada es una nueva saltahojas invasiva en Norteamérica. Es originaria del norte de China y se ha extendido a otras partes de Asia, incluidos Vietnam, Japón y Corea del Sur, donde está causando daños significativos a la vid.
Biophysically-Informed Models Of Heterogeneity In Transcription Factor Activity, Kaiser Loell
Biophysically-Informed Models Of Heterogeneity In Transcription Factor Activity, Kaiser Loell
Arts & Sciences Graduate Student Theses and Dissertations
The activity of a transcription factor (TF) can be remarkably heterogeneous, both within andbetween cells. Between cells, molecular fluctuations drive stochastic differences in the activitiesof TFs. I will describe a project in which we have quantified how the different components of aTF (its activation domain, affinity for DNA, concentration, and cooperative interactions) influencestochastic fluctuations in TF activity. In addition to stochastic fluctuations between cells, withincells TFs can switch between activating and repressing activities depending on the cis-regulatorycontent of their target genes. I will describe a second project in which we have modelled howthe balance between homo- and heterotypic interactions determines …
Leveraging The Intersectionality Of Healthcare And Hospitality To Diversify Workforce Talent And Enhance Patient Experience, Sven Gierlinger, Nicole Giammarinaro, Mallory Tuomey, Leah Petrosino
Leveraging The Intersectionality Of Healthcare And Hospitality To Diversify Workforce Talent And Enhance Patient Experience, Sven Gierlinger, Nicole Giammarinaro, Mallory Tuomey, Leah Petrosino
Patient Experience Journal
As healthcare becomes more of a consumerism-based industry, organizations and leaders are embracing innovative approaches and models to drive patient choice and brand loyalty. Northwell Health, New York State’s largest comprehensive health system, has integrated hospitality as a core pillar within its dynamic patient experience strategy. This informative case report highlights Northwell’s pragmatic approach to designing, implementing, and sustaining an experiential internship program entitled, Hospitality in Healthcare Internship. The program has resulted in action-oriented patient experience performance improvement opportunities as well as create a robust pipeline of hospitality-minded talent into the organization.
Experience Framework
This article is associated with the …
Caregiver Burden: Support Needed For Those Who Support Others And The National Health Service, Michael Stephanou
Caregiver Burden: Support Needed For Those Who Support Others And The National Health Service, Michael Stephanou
Patient Experience Journal
This literature review focuses on the complexities and inequalities of informal caregiving in the UK and was inspired by the story of the following individual: EL is a 68-year-old Caucasian lady who attended Movement Disorder Clinic and was diagnosed with Parkinson's Disease Dementia following many years of symptoms. The diagnosis came as a big relief to EL and her daughter (SL) who were eager to get treatment started as soon as possible. EL lives alone with SL and solely relies on her for care and support. SL does not have children and devotes her daily routine to looking after her …
Cancer Clinical Trials: The Role Of Healthcare Providers In Addressing Inequitable Racial/Ethnic Minority Representation In Biomedical Research, Jilian Maxine Jalipa Frianela, Gillian Leasunia Katoanga
Cancer Clinical Trials: The Role Of Healthcare Providers In Addressing Inequitable Racial/Ethnic Minority Representation In Biomedical Research, Jilian Maxine Jalipa Frianela, Gillian Leasunia Katoanga
Journal of Vincentian Social Action
No abstract provided.
Exploring Sexual Health Education Disparities Among Latina Immigrants In Jackson Heights, N.Y., Maria Camila Lopez, Hira Shafeeq
Exploring Sexual Health Education Disparities Among Latina Immigrants In Jackson Heights, N.Y., Maria Camila Lopez, Hira Shafeeq
Journal of Vincentian Social Action
The purpose of the current study is to explore the factors that influence sexual health decisions of female Latina immigrants with low socioeconomic status in an urban area. We aimed to evaluate the possible preventive steps to lower their risk of contracting STDs. The need for this study was highlighted by research findings that suggest that health disparities among Hispanic immigrants have had a significant impact on their poor quality of life due to lack of proper access to medical care and misdiagnosis due to differences in risk factors and manifestations of the disease. Sexual health is a constant issue …
Sensing The Rhizosphere: Microbial Transcriptome Responses To Root Exudates And Redox-Active Metabolites, Ankita Bhattacharyya
Sensing The Rhizosphere: Microbial Transcriptome Responses To Root Exudates And Redox-Active Metabolites, Ankita Bhattacharyya
Dissertations
The term “rhizosphere” describes the dynamic interface between plant roots and soil influenced by root exudates. It is a hotspot of microbial activity, plant-microbe, and microbe-microbe interactions. Distinct variations in bacterial diversity are thought to be driven by plant root exudates. However, the molecular details of these processes still remain unclear.
I addressed this gap by focusing on two strains, Pseudomonas synxantha 2-79 and Burkholderia lata 383, representing diverse groups of Gammaproteobacteria comprised of species with environmental, agricultural, and medical significance. In the first part of this project, we used a combination of metabolomics and RNA-seq to characterize transcriptome responses …
The Impact Of Soil Disturbance On Soil Bacterial Community Composition, Marie A. Rodriguez, Mark Peach, Timothy D. Trott
The Impact Of Soil Disturbance On Soil Bacterial Community Composition, Marie A. Rodriguez, Mark Peach, Timothy D. Trott
Research in Biology
Soil bacterial communities are an important part of terrestrial ecosystems due to their roles in biogeochemical cycling processes. Consequently, understanding how soil disturbance affects the soil bacterial diversity is vital to understanding the entire ecosystem. In this study we examined the effects of soil disturbance (by mining) on the soil bacterial community composition from three sites on Bauxite Ridge in Southeast Tennessee compared to three undisturbed sites in a nearby location. The soil bacterial community was analyzed by 16S rDNA amplicon sequencing of total DNA extracted from the soil samples collected from each of the six sites. Characterization of the …
Examining The Different Soil Horizons Of White Oak Mountain, Tn And Their Effect On The Soil Microbial Community, Ji Won Moon, Timothy D. Trott
Examining The Different Soil Horizons Of White Oak Mountain, Tn And Their Effect On The Soil Microbial Community, Ji Won Moon, Timothy D. Trott
Research in Biology
Soil microorganisms participate in the diverse interaction within virtually all ecosystems, consequently affecting the associated human and animal population. Identifying how edaphic variables alter the functional and taxonomic diversity of the soil microbial community requires an examination of total microbial soil diversity and abundance. This research study examined the effect of soil depth and horizon on the soil microbial community composition of White Oak Mountain. The soil microbial community was characterized by 16S/18S/ITS rDNA amplicon sequencing of the DNA extract of six samples from the three major soil types identified: HcE, MoE, and uMvC. OTU clustering analysis and both alpha …
Internships Help Senior Biology Major Determine Her Career Path, Office Of University Communications
Internships Help Senior Biology Major Determine Her Career Path, Office Of University Communications
Gardner-Webb NewsCenter Archive
Senior biology major Karson Dean, of Dallas, N.C., has cared passionately about animals for as long as she can remember. When she graduates from Gardner-Webb University in December 2023, she plans to pursue a career in veterinary technology.
Holy Cross Magazine, Vol. 57, No. 3, Summer 2023, College Of The Holy Cross
Holy Cross Magazine, Vol. 57, No. 3, Summer 2023, College Of The Holy Cross
Holy Cross Magazine
“There’s No Chance That Two Women Would Win”
Spurred by the same challenge more than two decades apart, four female trailblazers proved the naysayers wrong and won election to the highest office in Holy Cross student government.
By Rebecca Smith ’99
“Your One Wild and Precious Life”
Alumnae in ministry: where faith and mission meet
By Marybeth Reilly-McGreen ’89
Holy Cross’ New Superpower
Beyond Marvel and DC, faculty are using the College’s burgeoning graphic novel collection as a centerpiece to teaching.
Story by Michael Bonner
Illustrations by Chris Escobar
The Unexpected Economists
For Holy Cross economics and accounting faculty, students …
Sick From Freedom: The Untold Story Of A Smallpox Epidemic Among Formerly Enslaved People, Jim Downs
Sick From Freedom: The Untold Story Of A Smallpox Epidemic Among Formerly Enslaved People, Jim Downs
Rondel V. Davidson Endowed Lecture Series
Emancipated from slavery, former bondspeople entered into an environment in which more soldiers died from disease than from battle. This talk explores the high rate of illness and mortality that devastated formerly enslaved people during the Civil War and Reconstruction. In particular, it provides the first analysis of the smallpox epidemic that began in Washington, DC in 1862 and then spread to the Lower South in 1863 and Mississippi Valley in 1864-65. By 1865, the epidemic plagued the entire South and began to move west and infected Native Americans on reservations. Due to the unexpected and inordinate mortality, the federal …
Phf8-Glul Axis In Lipid Deposition And Tumor Growth Of Clear Cell Renal Cell Carcinoma., Song Peng, Ze Wang, Peng Tang, Shuo Wang, Yiqiang Huang, Qiubo Xie, Yapeng Wang, Xintao Tan, Tang Tang, Xuzhi Yan, Jing Xu, Weihua Lan, Luofu Wang, Dianzheng Zhang, Bin Wang, Tiejun Pan, Jun Qin, Jun Jiang, Qiuli Liu
Phf8-Glul Axis In Lipid Deposition And Tumor Growth Of Clear Cell Renal Cell Carcinoma., Song Peng, Ze Wang, Peng Tang, Shuo Wang, Yiqiang Huang, Qiubo Xie, Yapeng Wang, Xintao Tan, Tang Tang, Xuzhi Yan, Jing Xu, Weihua Lan, Luofu Wang, Dianzheng Zhang, Bin Wang, Tiejun Pan, Jun Qin, Jun Jiang, Qiuli Liu
PCOM Scholarly Works
For clear cell renal cell carcinoma (ccRCC), lipid deposition plays important roles in the development, metastasis, and drug resistance. However, the molecular mechanisms underlying lipid deposition in ccRCC remain largely unknown. By conducting an unbiased CRISPR-Cas9 screening, we identified the epigenetic regulator plant homeodomain finger protein 8 (PHF8) as an important regulator in ccRCC lipid deposition. Moreover, PHF8 is regulated by von Hippel-Lindau (VHL)/hypoxia-inducible factor (HIF) axis and essential for VHL deficiency-induced lipid deposition. PHF8 transcriptionally up-regulates glutamate-ammonia ligase (GLUL), which promotes the lipid deposition and ccRCC progression. Mechanistically, by forming a complex with c-MYC, PHF8 up-regulates TEA domain transcription …
Redbird Buzz Episode 29: Dr. Taiwo Durowade '09, August 2, 2023, Rachel Kobus, Taiwo Durowade
Redbird Buzz Episode 29: Dr. Taiwo Durowade '09, August 2, 2023, Rachel Kobus, Taiwo Durowade
Redbird Buzz (2022-2025)
Dr. Taiwo Durowade ’09 is a board-certified obstetrician/gynecologist who has practiced in south suburban Chicago for the past five years. Durowade joins Redbird Buzz to discuss how—and why—she focuses her practice on preventative care. She also talks about utilizing social media to deliver free medical advice to maximize her impact.
Durowade earned a bachelor’s in biochemistry and molecular biology at Illinois State University in 2009. She went on to obtain her M.D. at the University of Illinois College of Medicine, followed by residency in Obstetrics and Gynecology in Ann Arbor, Michigan. She is featured in the summer 2023 State alumni …
Genetic Insights Into Resting Heart Rate And Its Role In Cardiovascular Disease, Yordi J Van De Vegte, Ruben N Eppinga, M Yldau Van Der Ende, Yanick P Hagemeijer, Yuvaraj Mahendran, Elias Salfati, Albert V Smith, Vanessa Y Tan, Dan E Arking, Ioanna Ntalla, Emil V Appel, Claudia Schurmann, Jennifer A Brody, Rico Rueedi, Ozren Polasek, Gardar Sveinbjornsson, Cecile Lecoeur, Claes Ladenvall, Jing Hua Zhao, Aaron Isaacs, Lihua Wang, Jian'an Luan, Shih-Jen Hwang, Nina Mononen, Kirsi Auro, Anne U Jackson, Lawrence F Bielak, Linyao Zeng, Nabi Shah, Maria Nethander, Archie Campbell, Tuomo Rankinen, Sonali Pechlivanis, Lu Qi, Wei Zhao, Federica Rizzi, Toshiko Tanaka, Antonietta Robino, Massimiliano Cocca, Leslie Lange, Martina Müller-Nurasyid, Carolina Roselli, Weihua Zhang, Marcus E Kleber, Xiuqing Guo, Henry J Lin, Francesca Pavani, Tessel E Galesloot, Raymond Noordam, Yuri Milaneschi, Katharina E Schraut, Marcel Den Hoed, Frauke Degenhardt, Stella Trompet, Marten E Van Den Berg, Giorgio Pistis, Yih-Chung Tham, Stefan Weiss, Xueling S Sim, Hengtong L Li, Peter J Van Der Most, Ilja M Nolte, Leo-Pekka Lyytikäinen, M Abdullah Said, Daniel R Witte, Carlos Iribarren, Lenore Launer, Susan M Ring, Paul S De Vries, Peter Sever, Allan Linneberg, Erwin P Bottinger, Sandosh Padmanabhan, Bruce M Psaty, Nona Sotoodehnia, Ivana Kolcic, Dcct/Edic Research Group, David O Arnar, Daniel F Gudbjartsson, Hilma Holm, Beverley Balkau, Claudia T Silva, Christopher H Newton-Cheh, Kjell Nikus, Perttu Salo, Karen L Mohlke, Patricia A Peyser, Heribert Schunkert, Mattias Lorentzon, Jari Lahti, Dabeeru C Rao, Marilyn C Cornelis, Jessica D Faul, Jennifer A Smith, Katarzyna Stolarz-Skrzypek, Stefania Bandinelli, Maria Pina Concas, Gianfranco Sinagra, Thomas Meitinger, Melanie Waldenberger, Moritz F Sinner, Konstantin Strauch, Graciela E Delgado, Kent D Taylor, Jie Yao, Luisa Foco, Olle Melander, Jacqueline De Graaf, Renée De Mutsert, Eco J C De Geus, Åsa Johansson, Peter K Joshi, Lars Lind, Andre Franke, Peter W Macfarlane, Kirill V Tarasov, Nicholas Tan, Stephan B Felix, E-Shyong Tai, Debra Q Quek, Harold Snieder, Johan Ormel, Martin Ingelsson, Cecilia Lindgren, Andrew P Morris, Olli T Raitakari, Torben Hansen, Themistocles Assimes, Vilmundur Gudnason, Nicholas J Timpson, Alanna C Morrison, Patricia B Munroe, David P Strachan, Niels Grarup, Ruth J F Loos, Susan R Heckbert, Peter Vollenweider, Caroline Hayward, Kari Stefansson, Philippe Froguel, Leif Groop, Nicholas J Wareham, Cornelia M Van Duijn, Mary F Feitosa, Christopher J O'Donnell, Mika Kähönen, Markus Perola, Michael Boehnke, Sharon L R Kardia, Jeanette Erdmann, Colin N A Palmer, Claes Ohlsson, David J Porteous, Johan G Eriksson, Claude Bouchard, Susanne Moebus, Peter Kraft, David R Weir, Daniele Cusi, Luigi Ferrucci, Sheila Ulivi, Giorgia Girotto, Adolfo Correa, Stefan Kääb, Annette Peters, John C Chambers, Jaspal S Kooner, Winfried März, Jerome I Rotter, Andrew A Hicks, J Gustav Smith, Lambertus A L M Kiemeney, Dennis O Mook-Kanamori, Brenda W J H Penninx, Ulf Gyllensten, James F Wilson, Stephen Burgess, Johan Sundström, Wolfgang Lieb, J Wouter Jukema, Mark Eijgelsheim, Edward L M Lakatta, Ching-Yu Cheng, Marcus Dörr, Tien-Yin Wong, Charumathi Sabanayagam, Albertine J Oldehinkel, Harriette Riese, Terho Lehtimäki, Niek Verweij, Pim Van Der Harst
Genetic Insights Into Resting Heart Rate And Its Role In Cardiovascular Disease, Yordi J Van De Vegte, Ruben N Eppinga, M Yldau Van Der Ende, Yanick P Hagemeijer, Yuvaraj Mahendran, Elias Salfati, Albert V Smith, Vanessa Y Tan, Dan E Arking, Ioanna Ntalla, Emil V Appel, Claudia Schurmann, Jennifer A Brody, Rico Rueedi, Ozren Polasek, Gardar Sveinbjornsson, Cecile Lecoeur, Claes Ladenvall, Jing Hua Zhao, Aaron Isaacs, Lihua Wang, Jian'an Luan, Shih-Jen Hwang, Nina Mononen, Kirsi Auro, Anne U Jackson, Lawrence F Bielak, Linyao Zeng, Nabi Shah, Maria Nethander, Archie Campbell, Tuomo Rankinen, Sonali Pechlivanis, Lu Qi, Wei Zhao, Federica Rizzi, Toshiko Tanaka, Antonietta Robino, Massimiliano Cocca, Leslie Lange, Martina Müller-Nurasyid, Carolina Roselli, Weihua Zhang, Marcus E Kleber, Xiuqing Guo, Henry J Lin, Francesca Pavani, Tessel E Galesloot, Raymond Noordam, Yuri Milaneschi, Katharina E Schraut, Marcel Den Hoed, Frauke Degenhardt, Stella Trompet, Marten E Van Den Berg, Giorgio Pistis, Yih-Chung Tham, Stefan Weiss, Xueling S Sim, Hengtong L Li, Peter J Van Der Most, Ilja M Nolte, Leo-Pekka Lyytikäinen, M Abdullah Said, Daniel R Witte, Carlos Iribarren, Lenore Launer, Susan M Ring, Paul S De Vries, Peter Sever, Allan Linneberg, Erwin P Bottinger, Sandosh Padmanabhan, Bruce M Psaty, Nona Sotoodehnia, Ivana Kolcic, Dcct/Edic Research Group, David O Arnar, Daniel F Gudbjartsson, Hilma Holm, Beverley Balkau, Claudia T Silva, Christopher H Newton-Cheh, Kjell Nikus, Perttu Salo, Karen L Mohlke, Patricia A Peyser, Heribert Schunkert, Mattias Lorentzon, Jari Lahti, Dabeeru C Rao, Marilyn C Cornelis, Jessica D Faul, Jennifer A Smith, Katarzyna Stolarz-Skrzypek, Stefania Bandinelli, Maria Pina Concas, Gianfranco Sinagra, Thomas Meitinger, Melanie Waldenberger, Moritz F Sinner, Konstantin Strauch, Graciela E Delgado, Kent D Taylor, Jie Yao, Luisa Foco, Olle Melander, Jacqueline De Graaf, Renée De Mutsert, Eco J C De Geus, Åsa Johansson, Peter K Joshi, Lars Lind, Andre Franke, Peter W Macfarlane, Kirill V Tarasov, Nicholas Tan, Stephan B Felix, E-Shyong Tai, Debra Q Quek, Harold Snieder, Johan Ormel, Martin Ingelsson, Cecilia Lindgren, Andrew P Morris, Olli T Raitakari, Torben Hansen, Themistocles Assimes, Vilmundur Gudnason, Nicholas J Timpson, Alanna C Morrison, Patricia B Munroe, David P Strachan, Niels Grarup, Ruth J F Loos, Susan R Heckbert, Peter Vollenweider, Caroline Hayward, Kari Stefansson, Philippe Froguel, Leif Groop, Nicholas J Wareham, Cornelia M Van Duijn, Mary F Feitosa, Christopher J O'Donnell, Mika Kähönen, Markus Perola, Michael Boehnke, Sharon L R Kardia, Jeanette Erdmann, Colin N A Palmer, Claes Ohlsson, David J Porteous, Johan G Eriksson, Claude Bouchard, Susanne Moebus, Peter Kraft, David R Weir, Daniele Cusi, Luigi Ferrucci, Sheila Ulivi, Giorgia Girotto, Adolfo Correa, Stefan Kääb, Annette Peters, John C Chambers, Jaspal S Kooner, Winfried März, Jerome I Rotter, Andrew A Hicks, J Gustav Smith, Lambertus A L M Kiemeney, Dennis O Mook-Kanamori, Brenda W J H Penninx, Ulf Gyllensten, James F Wilson, Stephen Burgess, Johan Sundström, Wolfgang Lieb, J Wouter Jukema, Mark Eijgelsheim, Edward L M Lakatta, Ching-Yu Cheng, Marcus Dörr, Tien-Yin Wong, Charumathi Sabanayagam, Albertine J Oldehinkel, Harriette Riese, Terho Lehtimäki, Niek Verweij, Pim Van Der Harst
Faculty, Staff and Student Publications
Resting heart rate is associated with cardiovascular diseases and mortality in observational and Mendelian randomization studies. The aims of this study are to extend the number of resting heart rate associated genetic variants and to obtain further insights in resting heart rate biology and its clinical consequences. A genome-wide meta-analysis of 100 studies in up to 835,465 individuals reveals 493 independent genetic variants in 352 loci, including 68 genetic variants outside previously identified resting heart rate associated loci. We prioritize 670 genes and in silico annotations point to their enrichment in cardiomyocytes and provide insights in their ECG signature. Two-sample …
Certified Occupational Health Nurses: Advocating For The Workforce And Work Environment, Lucille F. Carlson
Certified Occupational Health Nurses: Advocating For The Workforce And Work Environment, Lucille F. Carlson
Creating Healthy Work Environments (CHWE)
Occupational health nursing is the specialty practice that provides health, safety, and wellness programs and services to workers. The practice focuses on promotion of health, prevention of illness/injury, and protection from work-related and environmental hazards. The presentation will focus on benefits of certification in advocacy for workforces and work environments.
Genetic Insights Into Resting Heart Rate And Its Role In Cardiovascular Disease, Yordi J Van De Vegte, Lihua Wang, Dabeeru C Rao, Et Al.
Genetic Insights Into Resting Heart Rate And Its Role In Cardiovascular Disease, Yordi J Van De Vegte, Lihua Wang, Dabeeru C Rao, Et Al.
2020-Current year OA Pubs
Resting heart rate is associated with cardiovascular diseases and mortality in observational and Mendelian randomization studies. The aims of this study are to extend the number of resting heart rate associated genetic variants and to obtain further insights in resting heart rate biology and its clinical consequences. A genome-wide meta-analysis of 100 studies in up to 835,465 individuals reveals 493 independent genetic variants in 352 loci, including 68 genetic variants outside previously identified resting heart rate associated loci. We prioritize 670 genes and in silico annotations point to their enrichment in cardiomyocytes and provide insights in their ECG signature. Two-sample …
Leveraging Steric Moieties For Kinetic Control Of Dna Strand Displacement Reactions, Drew Lysne, Tim Hachigian, Chris Thachuk, Jeunghoon Lee, Elton Graugnard
Leveraging Steric Moieties For Kinetic Control Of Dna Strand Displacement Reactions, Drew Lysne, Tim Hachigian, Chris Thachuk, Jeunghoon Lee, Elton Graugnard
Materials Science and Engineering Faculty Publications and Presentations
DNA strand displacement networks are a critical part of dynamic DNA nanotechnology and are proven primitives for implementing chemical reaction networks. Precise kinetic control of these networks is important for their use in a range of applications. Among the better understood and widely leveraged kinetic properties of these networks are toehold sequence, length, composition, and location. While steric hindrance has been recognized as an important factor in such systems, a clear understanding of its impact and role is lacking. Here, a systematic investigation of steric hindrance within a DNA toehold-mediated strand displacement network was performed through tracking kinetic reactions of …
Using A Team Of Teams Approach To Optimize The Work Environment And Decrease Clabsi Rates, Warren Boudreau, Mona Clark, Sheranda Fesler, Tjin Koy, Tanya Nelson-Hall, Lauren Salinas
Using A Team Of Teams Approach To Optimize The Work Environment And Decrease Clabsi Rates, Warren Boudreau, Mona Clark, Sheranda Fesler, Tjin Koy, Tanya Nelson-Hall, Lauren Salinas
Creating Healthy Work Environments (CHWE)
The purpose of this activity is to introduce the Team of Teams approach and discuss its application to the promotion of a healthy work environment through interprofessional communication and collaboration, and the subsequent reduction of catheter line-associated bloodstream infection incidence and rates.
Alternative Splicing Of Ceacam1 By Hypoxia-Inducible Factor-1Α Enhances Tolerance To Hepatic Ischemia In Mice And Humans, Kenneth J Dery, Hidenobu Kojima, Shoichi Kageyama, Kentaro Kadono, Hirofumi Hirao, Brian Cheng, Yuan Zhai, Douglas G Farmer, Fady M Kaldas, Xiaoyi Yuan, Holger K Eltzschig, Jerzy W Kupiec-Weglinski
Alternative Splicing Of Ceacam1 By Hypoxia-Inducible Factor-1Α Enhances Tolerance To Hepatic Ischemia In Mice And Humans, Kenneth J Dery, Hidenobu Kojima, Shoichi Kageyama, Kentaro Kadono, Hirofumi Hirao, Brian Cheng, Yuan Zhai, Douglas G Farmer, Fady M Kaldas, Xiaoyi Yuan, Holger K Eltzschig, Jerzy W Kupiec-Weglinski
Faculty, Staff and Student Publications
Although alternative splicing (AS) drives transcriptional responses and cellular adaptation to environmental stresses, its contributions in organ transplantation have not been appreciated. We have shown that carcinoembryonic antigen-related cell adhesion molecule (Ceacam1; CD66a), a transmembrane biliary glycoprotein expressed in epithelial, endothelial, and immune cells, determines donor liver transplant quality. Here, we studied how AS of Ceacam1 affects ischemia-reperfusion injury (IRI) in mouse and human livers. We found that the short cytoplasmic isoform Ceacam1-S increased during early acute and late resolution phases of warm IRI injury in mice. Transfection of Ceacam1-deficient mouse hepatocytes with adenoviral Ceacam1-S mitigated hypoxia-induced loss of …
Purification And Detection Of Antibiotic-Resistant Bacteria From Whole Blood With Nano-Sieve, Xinye Chen
Purification And Detection Of Antibiotic-Resistant Bacteria From Whole Blood With Nano-Sieve, Xinye Chen
Theses
Life-threatening bloodstream infections (BSI), such as sepsis, mainly caused by the body’s syndromic response to pathogen infection, are a major public health concern, leading to ~11 million deaths each year. The identification of sepsis presents significant challenges in the diagnostic process, as the isolation of low concentration pathogens from bodily fluids (e.g., human blood) is extremely demanding, and typically relies on time-consuming and complicated isolation processes. Therefore, this work aims to explore the potential of microfluidics as a powerful tool for rapid purification and concentration of antibiotic-resistant bacteria (ARB) from blood samples, meanwhile developing a molecular diagnostic technology by combining …
Skp2-Mediated Mlkl Degradation Confers Cisplatin-Resistant In Non-Small Cell Lung Cancer Cells, Huiling Zhou, Li Zhou, Qing Guan, Xuyang Hou, Cong Wang, Lijun Liu, Jian Wang, Xinfang Yu, Wei Li, Haidan Liu
Skp2-Mediated Mlkl Degradation Confers Cisplatin-Resistant In Non-Small Cell Lung Cancer Cells, Huiling Zhou, Li Zhou, Qing Guan, Xuyang Hou, Cong Wang, Lijun Liu, Jian Wang, Xinfang Yu, Wei Li, Haidan Liu
Faculty, Staff and Students Publications
Non-small cell lung cancer (NSCLC) is the most prevalent type of cancer and the leading cause of cancer-related death. Chemotherapeutic resistance is a major obstacle in treating NSCLC patients. Here, we discovered that the E3 ligase Skp2 is overexpressed, accompanied by the downregulation of necroptosis-related regulator MLKL in human NSCLC tissues and cell lines. Knockdown of Skp2 inhibited viability, anchorage-independent growth, and in vivo tumor development of NSCLC cells. We also found that the Skp2 protein is negatively correlated with MLKL in NSCLC tissues. Moreover, Skp2 is increased and accompanied by an upregulation of MLKL ubiquitination and degradation in cisplatin-resistant …
Collaborative Challenges Between Educational Accessibility Coordinators And Adjunct Faculty In Supporting Autism Spectrum Students, Tamara Faure, Pietro Antonio Sasso
Collaborative Challenges Between Educational Accessibility Coordinators And Adjunct Faculty In Supporting Autism Spectrum Students, Tamara Faure, Pietro Antonio Sasso
New York Journal of Student Affairs
Accessibility of educational accommodations has increased but can be frequently inconsistent for undergraduates with autism spectrum disorder (ASD). The didactic relationship between educational accessibility staff with faculty, who are increasingly adjuncts, facilitates many course-learning accommodations. This descriptive phenomenological study explored the perceptions and professional experiences of educational accessibility coordinators with adjunct faculty in their implementation of learning accommodation for undergraduates with ASD. Findings from this study suggested that accessibility coordinators negotiated expectations of unprepared adjunct faculty and ASD students to address issues throughout the semester.
Coordinators believed ASD students struggled to navigate their experiences with adjunct professors because they were …
Lgbtq Community College Students’ Decreased Sense Of Belonging, Joseph Falco, Michael Sparrow Ed.D.
Lgbtq Community College Students’ Decreased Sense Of Belonging, Joseph Falco, Michael Sparrow Ed.D.
New York Journal of Student Affairs
LGBTQ students experience a lower sense of belonging at community colleges. The correlation between campus and classroom climate and academic success, campus involvement, identity, level of outness, and well-being for LGBTQ students contributes to their decreased sense of belonging. Non-LGBTQ-affirming and non-inclusive community college campuses and classrooms lead to feelings of fear, invisibility, lack of validation, mental health challenges, and poor academic performance for LGBTQ students. An extensive literature review was conducted to determine the root causes around the decreased sense of belonging for LGBTQ students enrolled at community colleges. Three themes emerged that explained this decreased sense of belonging: …
Discovery Of An Introduced Florida Flagfish (Jordanella Floridae) Population In Coastal Mississippi, Robert Ellwanger, Samuel E. Hunt, Calvin R. Rezac, Matthew D. Wagner
Discovery Of An Introduced Florida Flagfish (Jordanella Floridae) Population In Coastal Mississippi, Robert Ellwanger, Samuel E. Hunt, Calvin R. Rezac, Matthew D. Wagner
Southeastern Fishes Council Proceedings
The recent discovery of Jordanella floridae (Florida Flagfish) in Harrison County, Mississippi represents the first known occurrence of the species in the state. Native along the Atlantic and Gulf Coasts of Florida from Jacksonville to Tallahassee, this species has been introduced outside of its range via aquarium introductions. We hypothesize that an aquarium introduction was also the source of the newly discovered population, which has persisted at the location since 2020. Multiple collections of the species have been taken from a small waterbody which has a direct connection to the Tchoutacabouffa River (25mm-47mm TL). While it is unknown if this …
Towards Ethical Ai: Mathematics Influences Human Behavior, Dioneia M. Monte-Serrat, Carlo Cattani
Towards Ethical Ai: Mathematics Influences Human Behavior, Dioneia M. Monte-Serrat, Carlo Cattani
Journal of Humanistic Mathematics
Mathematics plays an important role in the linguistic structure of artificial in- telligence (AI). We describe the linguistic process as a unique structure present both in human cognition and in cognitive computing. The close relationship with both AI and human cognition is due to this unique structure, which paves the way for AI to interfere with the behavior of those who interact with it. We highlight the role of mathematicians in designing algorithms—the core of the AI linguistic process—and in defining steps and instructions for AI. Because al- gorithms, through AI, interfere with the thought of those who interact with …
Beauty Of Life In Dynamical Systems: Philosophical Musings And Resources For Students, Soumya Banerjee, Joyeeta Ghose, Tarakeswar Banerjee, Kalyani Banerjee
Beauty Of Life In Dynamical Systems: Philosophical Musings And Resources For Students, Soumya Banerjee, Joyeeta Ghose, Tarakeswar Banerjee, Kalyani Banerjee
Journal of Humanistic Mathematics
Information plays a key role in life and in complex biological systems, and dynamical systems underlie and can be used to represent many complex systems. Indeed, dynamical systems and information processing capabilities may be the hallmarks of life-like systems. In this paper we combine dynamical systems with a computational framework to generate art. The framework can be used to generate aesthetically appealing forms of life-like systems. Our work suggests that we may need an ``aesthetic sense'' to recognize life that we have not seen before. We also provide teaching resources for students in schools and undergraduate institutions.
The "Benfordness" Of Bach Music, Chadrack Bantange, Darby Burgett, Luke Haws, Sybil Prince Nelson
The "Benfordness" Of Bach Music, Chadrack Bantange, Darby Burgett, Luke Haws, Sybil Prince Nelson
Journal of Humanistic Mathematics
In this paper we analyze the distribution of musical note frequencies in Hertz to see whether they follow the logarithmic Benford distribution. Our results show that the music of Johann Sebastian Bach and Johann Christian Bach is Benford distributed while the computer-generated music is not. We also find that computer-generated music is statistically less Benford distributed than human- composed music.
The Long Search For Collatz Counterexamples, Oliver K. Clay
The Long Search For Collatz Counterexamples, Oliver K. Clay
Journal of Humanistic Mathematics
Despite decades of effort, the Collatz conjecture remains neither proved, nor refuted by a counterexample, nor formally shown to be undecidable. This note introduces the Collatz problem and probes its logical depth with a test question: can the search space for counterexamples be iteratively reduced, and when would it help?
On Definitions Of "Mathematician", Ron Buckmire, Carrie Diaz Eaton, Joseph Hibdon, Katherine M. Kinnaird, Drew Lewis, Jessica Libertini, Omayra Ortega, Rachel Roca, Andrés R. Vindas Meléndez
On Definitions Of "Mathematician", Ron Buckmire, Carrie Diaz Eaton, Joseph Hibdon, Katherine M. Kinnaird, Drew Lewis, Jessica Libertini, Omayra Ortega, Rachel Roca, Andrés R. Vindas Meléndez
Journal of Humanistic Mathematics
The definition of who is or what makes a “mathematician” is an important issue to be addressed in the mathematics community. Too often, a narrower definition of who is considered a mathematician (and what is considered mathematics) is used to exclude people from the discipline—both explicitly and implicitly. However, using a narrow definition of a mathematician allows us to highlight, examine, and challenge systemic barriers that exist in certain spaces of the community. This paper analyzes and illuminates tensions between narrow and broad definitions and how they can be used to promote both inclusion and exclusion simultaneously. In this article, …