Digital Commons Network^™

The Role Of The British Grassland Society In Technology Transfer, J. M. Crichton

IGC Proceedings (1977-2023)

Since its formation in 1945, the British Grassland Society (BGS) has been active in disseminating information to the grassland and associated sectors of agriculture and has adapted to a change from production-based agriculture to its current output mix of private and public goods. The BGS has as its remit: (a) improved production and utilisation of grass and forage crops for the promotion of agriculture and the public benefit, and (b) the advancement of education and research in grass and forage crop production and utilisation, and the publication of results.

High Fiber Dietary Intervention Induces Change In Role Of Faecalibacterium Prausnitzii In Gut Microbiome Ecosystem, Daniel Cyrus Mousavi, Aditya Mishra, Nadim Ajami, Yan Jiang, Tessa M. Kus, Erma Levy, Marco Montalvo, Jennifer Wargo, Carrie Daniel Macdougall, Jennifer Mcquade

Summer Experience 2023

No abstract provided.

Enhancing The Design And Consistency Of An Α-Particle Irradiator For In Vitro Experiments, Benjamin M. Kohler, Marco Tulio Reis, Poliana Marinello, Gabriel Sawakuchi

Summer Experience 2023

No abstract provided.

Non-Coding Rna 886 Predicts Hpv Status And Survival In Oropharyngeal Squamous Cell Carcinoma Patients, Saawan Patel, Guojun Li

Summer Experience 2023

No abstract provided.

Enhancers Activation By Crispr/Cas9-Based Acetyltransferase Rescues Loss Of Function In Crebbp Point Mutant, Sarah S. Luke, Haopeng Yang, Michael R. Green

Summer Experience 2023

No abstract provided.

Integrating Cervical Cancer Prevention Services To Improve Healthcare Access In The Texas Rio Grande Valley, Alaina Le, Kathleen M. Schmeler, Melissa V. Lopez, Ellen Baker, Miila P. Salcedo, Jessica Milan, Monica Pippin, Reina Guerrero, Kidist Daniel

Summer Experience 2023

No abstract provided.

Characterizing The Importance Of Microglial Qki In The Progression Of Alzheimer’S Disease, Adithya Nair, Takese Mckenzie, Jian Hu

Summer Experience 2023

No abstract provided.

Ada News - 08/07/2023, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

National Science Foundation Grant To Help Researcher Improve Data Storage Capability, University Of Dayton

Blog: The Dayton Engineer

A University of Dayton researcher has secured $540,000 from the National Science Foundation (NSF) to aid his quest to find better ways to store and read the increasing amount of information in the world.

The Influence Of Personality Type On Patient Outcome Measures And Therapeutic Alliance In Patients With Low Back Pain, William J. Hanney, Fahim Dhalla, Chase Kelly, Alicia Tomberlin, Morey J. Kolber, Abigail T. Wilson, Paul A. Salamh

HPD Articles

Background: Low back pain (LBP) has been shown to have various biological, psychological, and social factors that affect prognosis. However, it is unclear how personality may influence self-reported outcome measures and therapeutic alliance (TA). Methods: Eysenck’s personality inventory was used to assess personality, while the numeric pain rating scale (NPRS), Oswestry Disability Index (ODI), Tampa Scale of Kinesiophobia (TSK), Global Rating of Change (GROC), and the Working Alliance Inventory (WAI) measured patient progress and relationship strength. All outcome measures were formulated in a single survey that both the therapist and patient completed electronically. Results: Sixty-seven patients with LBP and twenty-two …

Research Update - August 2023, Office Of Research

Research Update

No abstract provided.

National Science Foundation Grant To Help Researcher Improve Data Storage Capability, University Of Dayton

News Releases

A University of Dayton researcher has secured $540,000 from the National Science Foundation (NSF) to aid his quest to find better ways to store and read the increasing amount of information in the world.

Quantitative Benefits Of Reducing The Inferior Border Of Right-Sided Free Breathing Intact Breast Treatment Plans Regarding Liver Dose, Shelby Handshue

Masters Projects

Introduction

Breast cancer is a prevalent disease in the United States, affecting approximately one in eight women during their lifetime (Leaver & Washington, 2010). Advancements in medical treatments have evolved from mastectomy to a multidisciplinary approach. Radiation therapy plays a crucial role in preventing local recurrence after breast conserving surgery. Traditionally, whole breast irradiation has been administered over 25-28 fractions to a total dose of 45-50 Gray (Gy), followed by a boost of 5-8 fractions to the tumor bed. In recent times, hypofractionation, which involves a shorter treatment schedule of 15-16 fractions to a total dose of 42.5 Gy, followed …

The Addition Of Phosphorus And Potassium Fertilizer In The Generative Stage Of Job’S Tears Affects Yield Components, Yield, And Yield Quality, Fiky Yulianto Wicaksono, Salma Khairunnisa, Tati Nurmala, Aep Wawan Irwan

Jurnal Kultivasi

Job’s tears (Coix lacryma-jobi L.) is an indeterminate food crop that requires more than one-time application of fertilizer. This study aims to determine the effect of additional doses of phosphorus and potassium at the beginning of the generative phase as side dressing fertilization on yield components, yield, and yield quality of the Job’s tears plant. The research was conducted in dry season March - August 2021 at the Experimental Field of the Faculty of Agriculture, Universitas Padjadjaran at Jatinangor, Sumedang Regency around 750 m above sea level. The experimental design used randomized block design (RBD) consisting of nine treatments and …

Shift Change: Minimizing The Covid-19 Nursing Shortage And Decreasing Nursing Burnout, Suzanne R. Baker

MSN Capstone Projects

Burnout and the nursing shortage of the healthcare system is not a new issue for nurses, but the COVID-19 pandemic caused this problem to only get worse (Young, 2021). Most healthcare facilities are severely understaffed. The nursing shortage and symptoms of burnout among nurses working in the Intensive Care Units (ICU) and other high-demand COVID-19 nursing units have been magnified by the COVID-19 pandemic. Inferior working conditions such as increased work times, increased workload, and decreased training in the care of COVID-19 patients magnified nursing burnout and the ongoing nursing shortage (Galanis et al., 2021). Discovering ways to reduce the …

More Is Better Than One: The Effect Of Ensembling On Deep Learning Performance In Biochemical Prediction Problems, Jacob A. Stern

Theses and Dissertations

This thesis presents two papers addressing important biochemical prediction challenges. The first paper focuses on accurate protein distance predictions and introduces updates to the ProSPr network. We evaluate its performance in the Critical Assessment of techniques for Protein Structure Prediction (CASP14) competition, investigating its accuracy dependence on sequence length and multiple sequence alignment depth. The ProSPr network, an ensemble of three convolutional neural networks (CNNs), demonstrates superior performance compared to individual networks. The second paper addresses the issue of accurate ligand ranking in virtual screening for drug discovery. We propose MILCDock, a machine learning consensus docking tool that leverages predictions …

Analyzing The Impact Of Process-Oriented Technology In Programming Education, Kate Arendes

Theses

Currently, there exist several factors in programming education that deter novice programmers. Computer science students are often significantly penalized for programs that do not compile, reflecting how current teaching standards are focused on the product of the student’s efforts, rather than the independent pieces of code that would otherwise execute properly. Novice programmers struggle with interpreting error messages that identify where and why a program failed, but are written with the assumption that the author already has mastered the fundamental concepts that they are trying to implement. In the classroom, educators may show presentations with pre-written code or perform live …

Intouch Week Of August 7, 2023, New York Medical College

InTouch

• SOM Class of 2027 Dons White Coats for the First Time
• Dr. Blicharz is Named Director of Student Academic Support
• NYMC Faculty Ranks in Best Scientists in Medicine List
• The Office of Public Relations Fosters Communication and Engagement at NYMC
• NYMC Research | Professor Xiu-Min Li, M.D., M.S., and Devora Loike-Weinstein, SOM Class of 2026

Fan1 Removes Triplet Repeat Extrusions Via A Pcna- And Rfc-Dependent Mechanism, Ashutosh S. Phadte, Mayuri Bhatia, Hope Ebert, Haaris Abdullah, Essam Abed Elrazaq, Konstantin E. Komolov, Anna Pluciennik

Department of Biochemistry and Molecular Biology Faculty Papers

Human genome-wide association studies have identified FAN1 and several DNA mismatch repair (MMR) genes as modifiers of Huntington’s disease age of onset. In animal models, FAN1 prevents somatic expansion of CAG triplet repeats, whereas MMR proteins promote this process. To understand the molecular basis of these opposing effects, we evaluated FAN1 nuclease function on DNA extrahelical extrusions that represent key intermediates in triplet repeat expansion. Here, we describe a strand-directed, extrusion-provoked nuclease function of FAN1 that is activated by RFC, PCNA, and ATP at physiological ionic strength. Activation of FAN1 in this manner results in DNA cleavage in the vicinity …

The Relationships Between Parenting Stress, Growth, And Development In Infants With Congenital Heart Defects During The First Six Months Of Life, Danica F. Sumpter

Dissertations

The stress experienced by parents at the time of diagnosis and hospitalization for their infant's congenital heart defect (CHD) is well recognized by healthcare professionals. Increased parenting stress has been negatively correlated with development in low birthweight infants. The primary purpose of this study was to explore the parenting stress as experienced by parents of infants with CHD during their first six months of life. In addition, the relationship between parenting stress and the growth and development of infants with CHD was explored. Due to the transactional nature of mother-infant interaction, both directions of this relationship were examined, the factors …

Identification Of Extreme Weather And Their Correlation On Soybean Production In Garut Regency, Ruminta, Fiky Yulianto Wicaksono, Annisa Nurinnida, Agus Wahyudin

Jurnal Kultivasi

The phenomenon of extreme weather events as a result of the impact of climate change can cause threats to agricultural systems, including soybean (Glycine max L.). Soybean is the main source of vegetable protein, which is sensitive and vulnerable to climate change. Therefore, research has been carried out through the identification analysis of changes in extreme weather events and analyzed for their correlation with soybean crops in Garut Regency to determine the effect of extreme weather elements on soybean production. The method used in this research is descriptive quantitative, using trend analysis on extreme weather with data on extreme weather …

Testing Of Resistance To Downy Mildew On Several Sweet Corn Inbred Lines Of 7th Generation, Heri Kustanto

Jurnal Kultivasi

Sweet corn is one of the most well-known horticultural crop commodities and can adapt to various climates and environments. Efforts to control downy mildew disease continue to be carried out in collaboration with various parties in different ways, including genetic improvement of the varieties planted. The purpose of this study was to test the resistance of the 7th generation of sweet corn inbred lines to downy mildew and to find out the phenotypic characters that affect downy mildew. The new inbred lines obtained from the results of a long breeding process will be better tested for resistance to downy mildew …

Traf3-Ewsr1 Signaling Axis Acts As A Checkpoint On Germinal Center Responses, Yanchuan Li, Lele Zhu, Chun-Jung Ko, Jin-Young Yang, Hongjiao Wang, Ganiraju Manyam, Jing Wang, Xuhong Cheng, Shuli Zhao, Zuliang Jie

Faculty, Staff and Student Publications

The formation of germinal centers (GCs) is crucial for humoral immunity and vaccine efficacy. Constant stimulation through microbiota drives the formation of constitutive GCs in Peyer's patches (PPs), which generate B cells that produce antibodies against gut antigens derived from commensal bacteria and infectious pathogens. However, the molecular mechanism that regulates this persistent process is poorly understood. We report that Ewing Sarcoma Breakpoint Region 1 (EWSR1) is a brake to constitutive GC generation and immunoglobulin G (IgG) production in PPs, vaccination-induced GC formation, and IgG responses. Mechanistically, EWSR1 suppresses Bcl6 upregulation after antigen encounter, thereby negatively regulating induced GC B …

Metabolic Liver Cancer: Associations Of Rare And Common Germline Variants In One-Carbon Metabolism And Dna Methylation Genes, Samuel O Antwi, Michael Heckman, Launia White, Irene Yan, Vivekananda Sarangi, Kimberly P Lauer, Joseph Reddy, Fowsiyo Ahmed, Swathi Veliginti, Ellis D Mejías Febres, Rikita I Hatia, Ping Chang, Laura Izquierdo-Sanchez, Loreto Boix, Angela Rojas, Jesus M Banales, Maria Reig, Per Stål, Manuel Romero Gómez, Amit G Singal, Donghui Li, Manal M Hassan, Lewis R Roberts, Tushar Patel

Faculty, Staff and Student Publications

Animal studies implicate one-carbon metabolism and DNA methylation genes in hepatocellular carcinoma (HCC) development in the setting of metabolic perturbations. Using human samples, we investigated the associations between common and rare variants in these closely related biochemical pathways and risk for metabolic HCC development in a multicenter international study. We performed targeted exome sequencing of 64 genes among 556 metabolic HCC cases and 643 cancer-free controls with metabolic conditions. Multivariable logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs), adjusting for multiple comparisons. Gene-burden tests were used for rare variant associations. Analyses were performed in …

Metabolic Liver Cancer: Associations Of Rare And Common Germline Variants In One-Carbon Metabolism And Dna Methylation Genes, Samuel O Antwi, Michael Heckman, Launia White, Irene Yan, Vivekananda Sarangi, Kimberly P Lauer, Joseph Reddy, Fowsiyo Ahmed, Swathi Veliginti, Ellis D Mejías Febres, Rikita I Hatia, Ping Chang, Laura Izquierdo-Sanchez, Loreto Boix, Angela Rojas, Jesus M Banales, Maria Reig, Per Stål, Manuel Romero Gómez, Amit G Singal, Donghui Li, Manal M Hassan, Lewis R Roberts, Tushar Patel

Faculty, Staff and Student Publications

Animal studies implicate one-carbon metabolism and DNA methylation genes in hepatocellular carcinoma (HCC) development in the setting of metabolic perturbations. Using human samples, we investigated the associations between common and rare variants in these closely related biochemical pathways and risk for metabolic HCC development in a multicenter international study. We performed targeted exome sequencing of 64 genes among 556 metabolic HCC cases and 643 cancer-free controls with metabolic conditions. Multivariable logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs), adjusting for multiple comparisons. Gene-burden tests were used for rare variant associations. Analyses were performed in …

Evaluating The Osteogenic Potential Of Raspberry Ketone And Simvastatin Dual-Loaded Electrospun Chitosan Membranes On Preosteoblasts, Matthew T. Atwill

Electronic Theses and Dissertations Archive

This study evaluated the osteogenic potential of dual-loading raspberry ketone (RK) and simvastatin (SMV) onto electrospun chitosan membranes (ESCMs) to impart bioactivity onto guided bone regeneration (GBR) membranes and give them a more active role in osteodifferentiation. In this study, W-20-17 cells in media exposed to 12-100µg/ml RK in combination with 75-150ng/ml SMV resulted in increased basal alkaline phosphatase (ALP) expression, whereas RK groups alone had no effect on ALP expression. Additionally, there was a dose-dependent combinatory cytotoxic effect in which SMV in combination with increasing concentrations of RK resulted in decreased viability and vice versa. RK+SMV combinations were loaded …

Inéire: An Interpretable Nlp Pipeline Summarizing Inclusive Policy Making Concerning Migrants In Ireland, Arefeh Kazem, Arjumand Younus, Mingyeong Jeon, Muhammad Atif Qureshi, Simon Caton

Articles

Reaching marginal and other migrant communities to elicit their political views and opinions is a well-known challenge. Social media has enabled a certain amount of online activism and participation, especially in societies with abundant multicultural identities. However, it can be quite challenging to isolate the voice of the migrant in English-speaking countries, especially with an abundance of content in English on social media. In this paper, we pursue a case study of Ireland’s Twitter landscape, specifically migrant and native activists. We present a methodology that can accurately ( >80% ) isolate the Irish migrant voice with as little as 25 …

“We’Re Not A Band That Everybody Gets”: Parsing The Spectacle Of They Might Be Giants, Rachel Eliza Jones

Arts & Sciences Graduate Student Theses and Dissertations

After releasing twenty-three studio albums and performing together for four decades under the name They Might Be Giants—first as a duo and then, beginning in 1992, with a full backing band—John Flansburgh and John Linnell have certainly established a niche for themselves within the world of alternative rock. The band achieved a brief glimpse of mainstream commercial success in 1990 with the release of their third album, Flood, and in the years since, they’ve maintained a foothold in popular culture through their music for film and television, as well as the release of four children’s albums, one of which earned …

Roles Of Type I Interferon Signaling In Drug Resistant Mycobacterium Tuberculosis Infection, Suhas Bobba

Arts & Sciences Graduate Student Theses and Dissertations

Tuberculosis (TB) is a global health threat, with 10 million people developing active TB disease and a million deaths attributed to TB annually. Emergence of drug resistance in Mycobacterium tuberculosis (Mtb), the causative agent of TB, has led to half a million cases of drug resistant (DR) TB annually. Further, clinical reports suggest dysregulation and suppression of immune responses in DR TB patients as compared with DS TB patients. However, we do not understand how acquisition of drug resistance-conferring mutations can drive broad and systemic differences in immune responses of DR TB patients. We found that rpoB-H445Y a specific DR …

Drivers And Dynamics Of Phytoplankton Communities And Harmful Algal Blooms In Mountain Lakes, Lara Stephanie Jansen

Dissertations and Theses

Harmful cyanobacterial blooms (cyanoHABs) are a complex and widespread disturbance in freshwater water bodies, impacting water quality for wildlife and human populations. While cyanobacteria often bloom in warm lakes impacted by human development like agriculture, blooms are increasingly reported in cooler waters with limited development in the surrounding watershed. As much of cyanoHAB research has focused on lakes in highly developed watersheds, the understanding of factors leading to cyanobacteria dominance and blooms in the absence of major development remains limited. Mountain lakes can serve as ideal systems to study bloom-forming cyanobacteria in watersheds with minimal development. In addition, mountain lakes …