Digital Commons Network^™

Evaluating The Impact Of Biosimilars In The Drug Market, Olivia Sitter

Theses

Drug pricing has increase to the point where many Americans are unable to afford prescriptions for both long- and short-term diseases. Within the last decade, U.S lawmakers have changed legislation so that biosimilars can be added into the drug market in hopes of creating affordable products. Biosimilars allow more options for consumers and add increased competition for manufactures which should decrease the overall price of the original biopharmaceutical the biosimilar is modeled after. In current research, the impact of biosimilars within the European Union has been investigated heavily, but the US approved biosimilars much later and there is less information …

Robochurch: Baptizing Bots And Sanctifying Silicon?, Peter Bellini

Witness

No abstract provided.

Galonsky V. East 17th Llc

All Decisions

No abstract provided.

From House Party To World Dominance: Celebrating 50 Years Of Hip Hop: A Bibliography, Cassandra Chaney

Journal of Hip Hop Studies

In 2023, the culture celebrated the 50th birthday of Hip Hop. While there is an ongoing argument of when Hip Hop started, Hip Hop culture marked Clive “DJ Kool Herc” Campbell’s legendary 1973 party at 1520 Sedgwick Avenue in the Bronx, NY as the day to commemorate its humble beginnings. This work provides a bibliographical list of published articles, interviews, book reviews, forthcoming books, and live performances from various artists that made a major impact on Hip Hop. In particular, the bibliography highlights the mark that Hip Hop has made on fashion, the economy, language, and the unique contributions that …

Improving Intimate Partner Violence Screening In A Women’S Health Practice Through Implementation Of An Evidence-Based Screening Tool, Jasmine Weber

Doctor of Nursing Practice Projects: College of Nursing

The purpose of this quality improvement project was to implement intimate partner violence screening in an outpatient women’s health clinic with no prior screening process in place. Current recommendations are to screen all reproductive age women for intimate partner violence 6 . During a three-month period 170 patients out of 260 eligible patients were screened using the HARK screening tool, 7 of those patients screened positive and were offered referrals to social work. While universal IPV screening was not achieved, a screening rate of 64% is a remarkable improvement from an apparent absence of screening prior to project implementation.

The Fall Of Public Opinion: The Tet Offensive, The Anti-War Movement, And The Media, 1963-1975, Taylor Ann Cusick

Electronic Theses & Dissertations

From 1963 to 1975, public opinion regarding the Vietnam War changed drastically. In the beginning, the public was largely on board with Americans going overseas to fight against the North Vietnamese military. Citizens felt the American military was doing what was necessary to secure democracy in a region where communism was spreading, and the public was not easily swayed by those who opposed the war. The media mirrored public opinion during the first years of the war. By 1968, support for the war declined dramatically, and the media’s portrayal of the conflict reversed. Newscasters began to argue that the risk …

Top Tips For Effective Use Of Periodontal Instruments In Primary Care, Morag Powell, Ruth Potterton, Ewen Mccoll

Peninsula Dental School

Stabilisation of primary disease is a key pillar of successful treatment and in addition to managing caries, managing periodontal disease is a crucial component of a successful treatment plan. The recent European Federation of Periodontology (EFP) S3 level clinical practice guidelines (CPG)1 are evidence‐based clinical guidelines providing recommendations to treat periodontitis. Crucial to successful implementation of these recommendations is delivering behavioural change and non-surgical instrumentation. Often this is given passing attention with insufficient time allocated to behaviour change in treatment planning. Similarly, poorly maintained periodontal instruments and equipment not used to their full utility or design can lead to poorer …

Introduction To Lgbtq+ Studies, Allison P. Brown, Deborah P. Amory

Milne Library

Introduction to LGBTQ+ Studies was a collaborative, multi-year open textbook project that engaged faculty authors, librarians, a university press, and OER professionals. The resulting textbook takes a cross-disciplinary approach to the study of LGBTQ+ issues that helps students grasp core concepts through a variety of different perspectives. The text offers accessible, academically sound information on a wide range of topics, including history, culture, and Queer Theory; an exploration of LGBTQ+ relationships, families, parenting, health, and education; and how to conduct research on LGBTQ+ topics. This case study will cover the project’s transformation through years of development, including engaging a large …

Aspirations Of Hispanic Criminal Justice Students To Join Law Enforcement: An Empirical Investigation, Yudu Li, Lucas Espinoza, Charlotte Hu, Fei Luo

Criminal Justice Faculty Publications

This study investigates the job preferences of criminal justice (CJ) students and potential factors that may impact their application for law enforcement positions. Existing research has shown that factors like gender, race, and class standing influence career choices among CJ majors. To contribute to this body of knowledge, this study focuses on CJ students’ attitudes toward the police and willingness to engage in community policing programs. The research examined 231 CJ students in a Hispanic serving university situated along the US-Mexican border. Research findings indicate that CJ students are less likely to pursue law enforcement careers if they hold less …

Modeling Of Frontal Polymerization Of Carbon Fiber And Dicyclopentadiene Woven Composites With Stochastic Material Uncertainty, Ahmadreza Mohammad Sharifi, Dong-Jun Kwon, S. Z. H. Shah, Juhyeong Lee

Mechanical and Aerospace Engineering Faculty Publications

A novel finite element modeling framework is proposed for simulating dicyclopentadiene (DCPD) frontal polymerization in carbon fiber (CF) woven composites. A mesoscale CF/DCPD representative volume element (RVE) model was developed with two triggering directions, resulting in out-of-plane and in-plane DCPD polymerization. The Arrhenius equation coupled with a modified Prout-Tompkins autocatalytic model was used to evaluate the dynamic DCPD polymerization process. The rate and degree of DCPD cure were calculated by the material property uncertainties of DCPD with and without random void inclusions (3% used as a reference in this work). The DCPD frontal polymerization in CF/DCPD composite was strongly influenced …

Disinfecting The Criminal Legal System Of Punitive Deterrence, Joseph Dole

DePaul Journal for Social Justice

No abstract provided.

Public Interest Burnout: Seven Factors That Increase The Risk, Sandra Simkins

DePaul Journal for Social Justice

No abstract provided.

Titles And Pronouns In The Academy: Academic Freedom And In-Class Speech Pursuant To Classroom Management, Michael K. Park

DePaul Journal for Social Justice

No abstract provided.

The Religious Landscape Of Uruguay In The Third Millennium: Present Piety As A Product Of The Past?, Brandon Kriplean

Honors Theses

Of all Latin American countries, Uruguay enjoys both the lowest percentage of Catholics and the highest percentage of religiously unaffiliated. The central aim of this thesis is to explore the extent to which historical secularization processes and laicidad are responsible for the low number of Catholics and the large number of religiously unaffiliated. With regards to the former, the historical evidence suggests that the small Catholic population is not a result of laicidad but is instead a product of internal issues within the Uruguayan Catholic Church. Part 1 of this thesis will explore the factors that have weakened the Uruguayan …

Resocializing Medical-Surgical Nurses On The Inpatient Handoff Sepsis Bundle Checklist, Maram Abuzahriyeh

Master's Projects and Capstones

Abstract

Problem: In September 2023, Hospital X identified a lack of utilization of the Inpatient Handoff Sepsis Bundle Checklist (IHSBC) in the medical-surgical unit with only 25% of nurses being familiar with it. This project aimed to improve the use of the IHSBC to maintain compliance of the sepsis bundle above the benchmark of 75%.

Context: A microsystem assessment was completed in a medical-surgical unit by CNL students at Hospital X. The students collaborated with Hospital X and identified the need to improve the socialization of the IHSBC in the medical-surgical unit.

Interventions: The intervention included resocializing the IHSBC on …

Exploring Ways To Reveal Consumer Buying Behavior In The Qatari Market, Angelika Barczak

Studia i Materiały Wydział Zarządzania Uniwersytet Warszawski

Purpose: The purpose of the study is to look for ways to reveal the purchasing behavior of consumers in Qatar. Design/Methodology/Approach: The study begins with a literature search on the subject. Some of the theories regarding the determinants of consumer purchasing behavior that are universal across cultures are specified. Then, an analysis of the cultural conditions of the Qatari market was carried out using Hofstede’s model. In the next step information from international literature on consumer behavior in Qatar was collected, analyzed and summarized. The information from the literature research was compiled and compared with the results of the analysis …

Understanding Unacceptable Graduation Outcomes For Historically Excluded Trio Student Support Services Students, Erica Willis

Electronic Theses and Dissertations

The primary purpose of this mixed-methods study is to define the problem and to understand the system that has been leading to unacceptably low graduation outcomes for historically excluded Trio Student Support Services (Trio SSS) students at Mid-Atlantic University (MAU), a pseudonym. To achieve the primary purpose extant documents and institutional data that can shed light on system processes and institutional conditions that perpetuate disparities in graduation outcomes, particularly for historically excluded racial groups that exist at the intersection of first-generation status and/or low socioeconomic status, will be analyzed. The secondary purpose of this study is to identify potential change …

The Contribution Of Principlism To Foster Ethical And Clinical Reciprocity In Resolving Healthcare Dilemmas, Dominic Glorioso

Electronic Theses and Dissertations

Principlism is an ethical method that uses an analytical framework based on a set of principles that can function as guidelines for healthcare professionals. The term was made

famous by the work of two bioethicists, Tom L. Beauchamp and James F. Childress. Their book, Principles of Biomedical Ethics and its multiple editions described a set of norms that are basic

for biomedical ethics. The first edition of their book was published in 1979, and the ninth edition in 2019. Its persistence and durability speak for themselves. In addition, their writings made

famous the four bioethical principles of respect for Autonomy, …

The Normative Requirement For Shared Decision Making (Sdm) In Healthcare Ethics, Margaret Nornor-Quadjie

Electronic Theses and Dissertations

Medicine and medical technology started to advance after World War II. During that period, the practice of medicine became technical. A lot began to happen in the biomedical world during the period after WWII that attracted comments, criticisms, and analyses from scholars. Perhaps, the 1947 Doctors’ Trial at the Nuremberg Tribunal and the Nuremberg Code may be said to be the defining moment for bioethics. These events eventually led to, in the United States, the passage of the National Research Act of 1974 that established the Institutional Review Board system and the National Commission for Protection of Human Subjects of …

Comparative Functional And Genomic Analysis Of Protein Targets Of Sexual Selection In Primates, Brianna Ports

Electronic Theses and Dissertations

Sexual selection is driven by the differential reproductive success of individuals, which is influenced by competition for mates and mate choice. In primates, this selective pressure has been attributed to the development of distinct anatomical, physiological, and behavioral characteristics. By employing comparative functional and genomic methodologies, this study aimed to assess the repercussions of primate sexual selection. To better understand the mechanisms driving sexually selected traits, an unbiased genome-wide analysis was used to associate rates of protein evolution with relative testes size and sexual size dimorphism. While previous research focused on the rapid evolution of male reproductive proteins in response …

Factors Affecting Adoption Of Tiktok Among Students In The Dhaka City Area., Mahafizur R. Jim, Muhammad I. Alam

Business Review

This study investigates the factors affecting adoption of TikTok among the students in Dhaka city area. A structured survey questionnaire was developed through the survey tool, Google form and data were obtained from 529 respondents living in various locations of Dhaka city by an online survey method through using the social media platform, Facebook. Moreover, the multiple regression analysis was performed to test the research hypotheses. Results show that students perceive this app in a different way and do not consider this app as a great source of enjoyment. Moreover, they do not perceive this app as a decent media …

Maternal- Child Malnutrition In Nepal: A Policy Analysis, Garima Pokhrel

Doctors of Nursing Practice (DNP) Final Projects, 2020-current

Abstract

Background: The United States Agency for International Development (USAID 2021) data finds that in Nepal 17 percent of women between the ages of 15-49 and 30 percent of adolescent girls of age 15-19 years are underweight; and 36 percent of children under the age of 5 were stunted in Nepal in 2016.

Objective: To review Nepal’s current National Nutrition Policy and provide evidence-based recommendations to amend the policy in order to improve nutritional outcomes of the prenatal population and children under the age of 5 years.

Methods: Bardach’s Eightfold Path to Policy Analysis Methodology and the Sustainable Diet …

Using Clinical Staff-Initiated Protocols In The Urgent Care Setting To Improve Throughput, Holly S. Mason

Doctors of Nursing Practice (DNP) Final Projects, 2020-current

One of the goals and purposes of the urgent care setting is to provide quality patient care within a timely fashion. This process improvement project was designed to improve patient visit times in the urgent care setting, thus improving throughput. In this project, testing/imaging protocols were developed, agreed upon by the office healthcare providers, and utilized by clinical staff for patients who presented with complaints of 1) dysuria, 2) sore throat with an accompanying fever, 3) upper respiratory symptoms without an accompanying fever, 4) upper respiratory symptoms with an accompanying fever, and 5) an orthopedic injury known as a FOOSH …

Implementing A Standard Work Process For Food Insecurity Screening, Referral, And Connection Tracking In A Safety-Net Clinic, Aisha Keplinger

Doctors of Nursing Practice (DNP) Final Projects, 2020-current

Social determinants of health (SDOH) screening and referral programs are crucial to achieving health equity, fundamental to providing the best care, and are critical to the United States’ pursuit of the Institute for Healthcare Improvement’s (IHI) Triple Aim (Berwick et al., 2008). Employing the PRECEDE-PROCEED model, a systematic screening and referral program was implemented at a safety-net clinic to increase SDOH screening and referral rates, and to identify the number of patients who connect with community resources. The program was guided by the IHI Triple Aim framework and evaluated using the Institute of Medicine (IOM) Six Aims of Healthcare Quality …

"How Could Anyone But A Madman Have Thought This Sleeping Girl Dead?": L.T. Meade's Approach To The "Buried Alive" Literary Tradition In Support Of Death Certification Reform, Shelby Johnson

Theses and Dissertations

A March 1866 issue of The Lancet observes, "If a newspaper were in want of a startling story with which to enliven a dull copy in the 'off season,' it could not do better than select one with the heading "'Buried Alive'"("Premature Interment" 295). Stories of being buried alive gave readers of all backgrounds a thrill. However, the stories frustrated the medical and scientific communities who were quick to dismiss the threat of live burial as a possibility in a modern world. Drawing on the literary history of "buried alive" stories and medical knowledge surrounding death signs and catalepsy, this …

Understanding Obsessive Compulsive Disorder Among Racial And Ethnic Minority Groups: A Content Analysis, Tyson William Lovell

Theses and Dissertations

Historically, racial and ethnic minority (REM) communities have faced reduced access to resources for mental and emotional health issues. While research has placed a greater emphasis on REM experiences, there is still a need to further understand the unique contextual factors surrounding mental health challenges among these marginalized groups. Research on Obsessive Compulsive Disorder (OCD) among REM communities is one area in need of further evaluation. Therefore, this study is a content analysis of literature analyzing the current research focused on the intersection of REM communities and OCD experiences. The purpose of the study is to analyze OCD research among …

Aspirin And Nonaspirin Nonsteroidal Antiinflammatory Drug Use And Occurrence Of Colorectal Adenoma In Black American Women, Laura F White, Hemant K Roy, Lynn Rosenberg, Julie R Palmer, Jessica L Petrick

Faculty, Staff and Students Publications

Evidence suggests that aspirin use reduces the occurrence of colorectal neoplasia. Few studies have investigated the association among Black Americans, who are disproportionately burdened by the disease. We assessed aspirin use in relation to colorectal adenoma among Black women. The Black Women's Health Study is a prospective cohort of self-identified Black American women established in 1995. Participants reported regular aspirin use on baseline and follow-up questionnaires. Beginning in 1999, participants reported undergoing a colonoscopy or sigmoidoscopy, the only procedures through which colorectal adenomas can be diagnosed. Multivariable logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals …

Timigp: An R Package To Depict The Tumor Microenvironment From Bulk Transcriptomics

Faculty, Staff and Students Publications

Exploring the clinical relevance of diverse immune cell types within the tumor microenvironment is pivotal for unraveling cancer intricacies and developing treatments. Here, we present a protocol for using tumor immune microenvironment illustration based on gene pairs, an R package to deduce cell-cell interactions, unveiling the association between immune cell relative abundance and patient prognoses from bulk gene expression and survival data. We describe steps for harnessing cell-type markers derived from single-cell RNA sequencing data to map the tumor immune microenvironment across a spectrum of cancer types. For complete details on the use and execution of this protocol, please refer …

A Case Of Filgrastim-Induced Neutrophilic Dermatosis Of The Dorsal Hands In A Patient With Felty Syndrome, Theodore Rosen

Faculty, Staff and Students Publications

Neutrophilic dermatosis of the dorsal hands (NDDH) is a variant of Sweet syndrome that presents with erythematous bullae, papules/plaques, or pustules on the dorsal hands. It is most commonly associated with hematologic and solid organ malignancies, though cases of NDDH associated with inflammatory bowel disease, rheumatologic disorders, and medication exposure have also been described in the literature. Felty syndrome is a rare complication of long-standing rheumatoid arthritis characterized by neuropathy, splenomegaly, and neutropenia. Granulocyte colony stimulating factors (e.g., filgrastim) can be utilized to rescue the neutropenia observed in Felty syndrome, but this treatment may subsequently cause Sweet syndrome. Herein, we …

Early Cellular And Molecular Signatures Correlate With Severity Of West Nile Virus Infection, Sameet Mehta, Xiaomei Wang, Brent Vander Wyk, Shannon E Ronca, Heather Kang, Chih-Hung Chou, Benoit Fatou, Kinga K Smolen, Ofer Levy, Clary B Clish, Ramnik J Xavier, Hanno Steen, David A Hafler, J Christopher Love, Alex K Shalek, Leying Guan, Kristy O Murray, Steven H Kleinstein, Ruth R Montgomery

Faculty, Staff and Students Publications

Infection with West Nile virus (WNV) drives a wide range of responses, from asymptomatic to flu-like symptoms/fever or severe cases of encephalitis and death. To identify cellular and molecular signatures distinguishing WNV severity, we employed systems profiling of peripheral blood from asymptomatic and severely ill individuals infected with WNV. We interrogated immune responses longitudinally from acute infection through convalescence employing single-cell protein and transcriptional profiling complemented with matched serum proteomics and metabolomics as well as multi-omics analysis. At the acute time point, we detected both elevation of pro-inflammatory markers in innate immune cell types and reduction of regulatory T cell …