Digital Commons Network^™

Relative Adrenal Insufficiency Is A Risk Factor And Endotype Of Sepsis - A Proof-Of- Concept Study To Support A Precision Medicine Approach To Guide Glucocorticoid Therapy For Sepsis, Chia-Hua Wu, Ling Guo, Dan Hao, Qian Wang, Xiang Ye, Misa Ito, Bin Huang, Chieko Mineo, Philip W. Shaul, Xiang-An Li

Saha Cardiovascular Research Center Faculty Publications

Introduction: 25-60% of septic patients experience relative adrenal insufficiency (RAI) and glucocorticoid (GC) is frequently used in septic patients. However, the efficacy of GC therapy and whether GC therapy should be based on the status of RAI are highly controversial. Our poor understanding about the pathogenesis of RAI and a lack of RAI animal model present significant barriers to address these critical issues.

Methods: Scavenger receptor BI (SR-BI) regulates stress-induced GC (iGC) production in response to stress. We generated SF1CreSR-BIfl/fl mice and utilized the mice as a RAI model to elucidate the pathogenesis of RAI and GC therapy in sepsis. …

Swosu Research And Scholarly Activity Fair 2023, Swosu Office Of Sponsored Programs

SWOSU Research and Scholarly Activity Fair Programs

On behalf of the members of the University Research and Scholarly Activity Committee (USRAC) and the Office of Sponsored Programs (OSP) at Southwestern Oklahoma State University (SWOSU) - Welcome to the Thirtieth SWOSU Research and Scholarly Activity Fair! There are 77poster presentations and 2 oral presentations involving over 130 student and faculty researchers, writers, presenters, artists, collaborators, and faculty sponsors encompassing activities from the SWOSU College of Pharmacy; SWOSU School of Nursing & Allied Health Sciences; and SWOSU Departments of Allied Health Sciences; Art, Communication & Theatre; Biological Sciences; Business; Computer Science; Chemistry & Physics; Engineering Technology; Language & Literature; …

The Fall Of Fda Review, Daniel G. Aaron

Utah Law Faculty Scholarship

The U.S. Food and Drug Administration (FDA) is in crisis. FDA can hardly go a single day without an investigation, negative news story, or scholarly critique of the agency’s work. We have increasingly entrusted FDA—today, to the tune of 25% of the U.S. economy—with vetting the products we put in and on our bodies. But the array of problems facing the agency raises questions about whether it is equipped to succeed in the 21st century.

FDA’s core function is to oversee a special legal regime called “premarket review.” Congress has prohibited all marketing of certain types of products (like drugs) …

Powered By Momma: Implementing Expressed Breast Milk For Oral Immunotherapy In A Level Iv Nicu, Whitney Anderson, Haneen Elsharif, Nicole Fletcher, Brooke Prince

2022

No abstract provided.

Self-Reported Tea Consumption And Age-Related Macular Degeneration In U.S. Adults, Lindsey Halasz Shaffer

Graduate Research Theses & Dissertations

Background: Age-related Macular degeneration (AMD) is a multifaceted disease of aging that is currently one of the leading causes of blindness in the US. As aging populations continue to turn to alternatives to prevent age-related diseases, the use of tea antioxidants has been suggested as potential protectors against cellular degradation and oxidation within the retina. To date, no epidemiologic or cross-sectional studies have been conducted regarding the correlation between tea intake and AMD, as it has for other diseases of with antioxidant mitigation potential, such as cancer. Objective: The purpose of this cross-sectional study was to examine the correlation between …

Challenges Of The Community Eligibility Provision Of The National School Lunch Program: A Conversation About The Poverty Indicators In Education Working Groups, Tara Thomas, Devon Brenner

The Rural Educator

No abstract provided.

A Legislative Call-To-Action: Applying Capture Theory To Combat The Risk Of Private Industry’S Excess Influence Over The Fda’S Regulation Of Livestock Antibiotics, Nathaniel Richey

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Exploring The Mechanisms By Which Camel Lactoferrin Can Kill Salmonella Enterica Serovar Typhimurium And Shigella Sonnei, Hussein A. Almehdar, Nawal Abd El-Baky, Ehab H. Mattar, Raed S. Albiheyri, Atif Bamagoos, Abdullah A. Aljaddawi, Vladimir N. Uversky, Elrashdy M. Redwan

Molecular Medicine Faculty Publications

There is a continuously increasing pressure associated with the appearance of Salmonella enterica Serovar typhimurium (S. typhimurium) and Shigella sonnei (S. sonnei) that have developed pathogenic multiple antibiotic resistance and the cost of cure and control of these enterobacteriaceae infections increases annually. The current report for first time demonstrated the distinguished antimicrobial action of camel lactoferrin (cLf) obtained from the milk of different clans of camel in Saudi Arabia against S. typhimurium and S. sonnei. These cLf subtypes showed comparable antimicrobial potential when tested against the two bacterial strains but were superior to either bovine (bLf) …

Yield And Composition Variations Of The Milk From Different Camel Breeds In Saudi Arabia, Amr A. El-Hanafy, Yasser M. Saad, Saleh A. Alkarim, Hussein A. Almehdar, Fuad M. Alzahrani, Mohammed A. Almatry, Vladimir N. Uversky, Elrashdy M. Redwan

Molecular Medicine Faculty Publications

With the increasing interest in the identification of differences between camel breeds over the last decade, this study was conducted to estimate the variability of milk production and composition of four Saudi camel breeds during different seasons. Milk records were taken two days per week from females of Majahem, Safra, Wadha, and Hamra breeds distributed over Saudi Arabia. The milk yield during winter indicated that the weekly average of the Wadha breed was significantly lower (27.13 kg/week) than Majahem and Hamra breeds. The Safra breed had the lowest milk yield (30.7 kg/week) during summer. During winter, the Hamra breed had …

Figure Set Update: An Inquiry-Based Module Aligned With The 4dee Framework For Teaching About Functional Responses And Biological Control, Rosny Jean, Linda Auker, Suann Yang, Jeremy Hsu

Open Educational Resources

THE ISSUE

Biological control agents are used in a wide range of contexts to limit damage from pests. However, the broader ecological consequences of such agents often are unclear before ecological risk assessments are performed. This Figure Set guides students to think through potential consequences of using biological control agents, and then uses a specific study to challenge students to interpret results from laboratory and caged field experiments. This Figure Set also introduces the concept of functional responses to students.

FOUR DIMENSIONAL ECOLOGY EDUCATION (4DEE) FRAMEWORK

• Core Ecological Concepts:
• Organisms
• Resources and regulators
• Communities
• Predation
• Ecology Practices:
• Quantitative reasoning and …

Assessment Of Microplastics In The Surface Water Of Sitio Pulo, Navotas, Metro Manila, Mark Lester C. Galicia, Carl Luis P. Flestado, Jeff Ryan S. Magalong, Ronald Benz L. Rivera, Kim M. Villacorte, William Peter G. Sarmiento, Chester C. Deocaris

Applied Environmental Research

Microplastics are synthetic polymer particles with a length of 5 mm or less with no well-defined lower boundary. These debris particles are known to affect marine and aquatic organisms which poses a threat to biodiversity and marine resources. In this study, the isolated microplastic from the coastal and lagoon surface waters of Sitio Pulo is described. Sitio Pulo is a barrier island mangrove sanctuary located at Brgy. Tanza I, Navotas City surrounded by Manila Bay. The samples collected last July 4 and 25, 2019, were isolated, profiled, and analyzed. A total of four hundred forty-nine (449) microplastic fragments were isolated …

Impact Of Covid-19 Nationwide Lockdowns And Unlock Phases In India On River Water Quality Of Upper Part Of The Ganga River, Dhara Kakwani, Abha Kumari, Kumar Suranjit Prasad, Bablu Prasad

Applied Environmental Research

The river water quality index (RWQI) of the upper Ganga canal has been computed to assess the effect of lockdown and unlock phases lead down by COVID-19 in India. Geospatial distribution of RWQI from January 2019 to December 2021 in the study area revealed significant impacts of lockdown on water quality. However, unlock phases (post lockdown) have deteriorated water quality since August 2020 and reached to actual conditions of the river by August 2021. To evaluate the lockdown as a management strategy to clean the river, other factors were reviewed including rainfall data, migration, and other activities. The results revealed …

The Role Of Non-Traditional Medical Spaces In Fostering Community And Advocacy For Healthcare Reform, Stassi Kiousis

Theses & ETDs

This paper explores the role of non-traditional medical spaces within the healthcare system, with a focus on their increased use after the COVID-19 pandemic. These spaces are primarily utilized for vulnerable populations and have become an important tool for alleviating the burden placed on the traditional medical settings. The study consists of three chapters that delve into different aspects of non-traditional medical spaces. Chapter One examines the creation of these spaces through meaning-making, while Chapter Two explores how community is formed within them through education, networking, and celebration. The Third Chapter investigates the structural issues affecting non-traditional medical spaces and …

Current Status And Priorities Of Paediatric Oncology Nursing In Africa: A Synthesis Of Perspectives From Siop Africa Nurses, Glenn M. Afungchwi, Elianeth Kiteni, Mariam Ndagire, Biemba Maliti, Julia M. Challinor, Rachel Hollis

School of Nursing & Midwifery, East Africa

Introduction. As African countries adopt the global goal of improving childhood cancer survival to 60% by 2030, intentional actions are required to improve nursing. This report aims to describe the current status of paediatric oncology nursing in Africa.

Methods. We report on nursing-related aspects of a survey to map paediatric oncology services in Africa (2018–2019), document perceived nursing strengths and weaknesses (2017) and share nurses’ research priorities (2019). Additionally, we report on a survey to identify topics for a foundation course (2019) and the expressed perspective of African nurses about the status of paediatric oncology nursing across the continent (2022). …

Embodiment, Scholarship Pressures, And Eating Disordered Behaviors In Division Ii Collegiate Athletes, Kelsey Blum

West Chester University Doctoral Projects

The present study sought to explore embodiment, eating and exercise behaviors, and the pressures that Division II team-sport athletes face. Six female collegiate team-sport athletes with scholarships participated in a focus group and reflected on their relationships with their bodies, eating and exercise patterns, and pressures they experience as student athletes. Participants also completed questionnaires regarding their experiences with eating and embodiment. A reflexive thematic analysis (Braun & Clarke, 2013) resulted in an overarching theme of “pressure to perform impacts athletes’ lives”, reflecting the dominant message participants shared regarding intense pressures experienced by student athletes. This overarching theme expanded into …

Spring Commencement, April 30, 2023, Eastern Michigan University

Commencement Programs and Materials

No abstract provided.

Eastern Michigan University, Winter Commencement, December 17, 2023, Eastern Michigan University

Commencement Programs and Materials

No abstract provided.

L-Menthol: An Emerging Athletic Performance Enhancing Aid, Maitham Khanafer

Senior Honors Theses and Projects

Background: L-menthol is an emerging athletic performance-enhancing aid. This review serves as an analytic report of existing controlled trials in the scientific literature that have investigated this compound as a sports aid when administered via the novel method of mouth rinsing followed by expectoration. Methods: Data on menthol mouth rinsing was sourced from EBSCO PowerSearch, Medline, and NCBI. In addition to a systematic review of existing literature, the current review outlines a detailed protocol to evaluate menthol mouth rinsing on a treadmill time-to-exhaustion test. This protocol adds an additional feature of conducting blood work examining any changes in energy substrate …

Microbial Communities Improve Growth Of Slow-Growing, Uncommon Legumes In A Restored Prairie, Alex Chumney

Senior Honors Theses and Projects

Restored prairies are attempts at restoring native prairies, most of which have been lost. However, restoration is often challenging because native prairie plants, such as native prairie legumes, often fail to establish in restored prairies. We hypothesized legume’s failure to establish in restored prairies is due to changes in the microbial communities with which legumes have multi-mutualistic relationships: rhizobia and arbuscular mycorrhizal fungi (AMF). Additionally, we hypothesized that late successional legumes rely on multi-mutualistic relationships for establishment and growth more than early successional legumes, and would respond synergistically to rhizobia and AMF treatments. To test this, we inoculated eight native …

Palatability, Consumption, And Physiological Effects Of The Green Microalgae Chlorella Sp. As A Feed Substitute For The Western Honey Bee Apis Mellifera In A Laboratory Setting, Benjamin J. Nichols

Department of Entomology: Distance Master of Science Projects

Western honey bees Apis mellifera are vital pollinators which play a significant role in global food security. Honey bees are faced by numerous environmental pressures including lack of forage which lead to large losses annually of managed honeybee colonies. To offset these pressures, many beekeepers manage colonies with the addition of artificial diets, many of which contain products that do not meet the nutritional requirements needed by honey bees or require large amounts of resources to grow. Recent literature has indicated that algae may be a viable nutritional resource for honey bees, meeting the nutritional requirements needed, requiring less resources, …

Undergraduate Symposium, 2023, College Of Arts & Sciences

Undergraduate Symposium Programs

No abstract provided.

Annual Report: Nebraska Extension In Lancaster County, January 1, 2023 Through December 31, 2023

Lancaster County, Nebraska Extension: Reports

Lancaster County Extension information from 2023. Contents include:

1) About Extension - Lancaster County Extension mission statement, overview and impact reports;

2) Staff and Programs - staff directory and Extension Educator annual program summaries;

3) Financials - summaries of 2022-2023 budget expenditures and fiscal year 2023-2024 budget; and

4) Media - website and social media information, samples of our Nebline newsletter and local newspaper articles.

Exploring The Impact Of Pediatric Short Bowel Syndrome On Parent Well‐Being Using A Disease‐Specific Pilot Survey, Marie L. Neumann, Jessica Y. Allen, Amy Ladner, Swapna Kakani, Meaghann S. Weaver, David F. Mercer

Department of Communication Studies: Faculty Publications

Background: Children with short bowel syndrome (SBS) have complex care needs, most of which are met in the home by family caregivers who may experience a range of stressors unique to this experience. Prior research suggests that parents of children with SBS have poorer health‐related quality of life than peers parenting children without health needs, but the mechanisms shaping parent outcomes are understudied.

Methods: A pilot survey was developed using a community‐driven research design to measure the impact of disease‐specific items on parent‐perceived well‐being. The cross‐sectional survey, which included both closed‐ended and open‐ended items, was distributed to a …

Foreword: Symbiotic Perspectives On The Processes Of Biology And Art, Scott F. Gilbert

Biology Faculty Works

No abstract provided.

Linking Previous Experiences To Behavior And Health In The Honey Bee (Apis Mellifera), Rebecca R. Westwick

Theses and Dissertations--Entomology

An organism’s ability to respond to changing conditions can be vital to its success. Indeed, plasticity is a common feature of living organisms. Much of the research in this area, though, has focused on effects caused by environmental conditions. What has received relatively less attention is how social experiences and broader features of an organism’s social environment can lead to long-lasting changes in health and behavior. This knowledge gap exists despite the well-documented existence of health and behavioral effects after social interactions in certain taxa such as humans.

Social insects such as honey bees provide an excellent opportunity to better …

Institute Of Public Health Newsletter- Volume4, Issue2, Institute Of Public Health (Iph)

Institute of Public Health Newsletter (IPHNL) and Other Publications

No abstract provided.

Institute Of Public Health Newsletter- Volume5, Issue1, Institute Of Public Health (Iph)

Institute of Public Health Newsletter (IPHNL) and Other Publications

No abstract provided.

Eating Disorders And Autism: A Network Approach, Lillian C. King

Undergraduate Theses, Professional Papers, and Capstone Artifacts

This paper explores the overlap of ED and ASD symptoms, and evaluates the results of a study that used network analysis to investigate pathway and core ED and ASD comorbidity symptoms. Eating Disorders (EDs) and autism spectrum disorder (ASD) have several overlapping symptoms that may inform our understanding of both disorders. Increased knowledge of the overlap of EDs and ASD can improve the treatment of EDs in those with ASD.

Community Cultivation: Understanding The Value Of The Partnership Between Garden City Harvest And Missoula County Public Schools, Lyris Daker

Undergraduate Theses, Professional Papers, and Capstone Artifacts

No abstract provided.

Genetic Capitalism: The Anthropological Evolution Of Antibiotic Resistant Bacteria, Mehin Suleiman

Hispanic Studies Honors Papers

This thesis titled "Genetic Capitalism: The Anthropological Evolution of Antibiotic Resistant Bacteria" explores the evolution of antimicrobial resistance (AMR) genotypes in bacteria and its impact on our destruction of a once symbiotic relationship with bacterial species. By taking an anthropological approach, I investigate how material relations, social institutions, cultural meanings, and political relations within and beyond the microcosm of bacteria have led to mass bacterial resistance. In the course of my research, I examine the cultures of bacterial cultures and their interactions, as well as the language of bacteria and their social intelligence, in order to anthropomorphize bacterial species that …