Digital Commons Network^™

Office Of Research, Economic Engagement And Outreach Update, May 3, 2023, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

A Sister-Group Comparison Of Branching And Pedicellariae In Brittlestar S (Echinodermata: Ophiuroidea), Richard L. Turner, Brenna O. O'Neill

Ocean Engineering and Marine Sciences Faculty Publications

Branching of arms and presence of pedicellariae are characters among ophiuroids found only in the order Euryalida (snakestars and basketstars). Family Asteronychidae has neither character; family Euryalidae has 2 small clades with branched arms; and family Gorgonocephalidae has all species with pedicellariae and 3 or 4 clades with branched arms. Despite the rare occurrence of these characters in the Ophiuroidea, they might be key adaptations within the Euryalida that have led to relatively high diversification. Sister-group comparison of the distribution of these 2 characters among taxa indicates that neither character alone explains diversity patterns within the order. In particular, branching …

Pathogenesis Of Oral Toxicities Associated With Targeted Therapy And Immunotherapy, Alessandro Villa

All Publications

Targeted therapy and immunotherapy have redefined cancer treatment. While they have enhanced tumor response and improved survival rates in many cancer types, toxicities continue to occur, and these often involve the oral cavity. Broadly reported as "mucositis" or "stomatitis," oral toxicities induced by targeted therapies differ clinically and mechanistically from those associated with conventional chemotherapy. Manifesting primarily as mucosal lesions, salivary gland hypofunction, or orofacial neuropathies, these oral toxicities may nonetheless lead to significant morbidity and impact patients' quality of life, thereby compromising clinical outcomes. We conclude that familiarity with the spectrum of associated toxicities and understanding of their pathogenesis …

Cross-Study Evaluation Of The Relationship Between The Human Gut Microbiome And Heart Disease, Anna Ali, Michael B. Burns

Undergraduate Research and Engagement Symposium

Heart disease is the number one cause of death globally, characterized by disorders of the arteries and blood flow. The human microbiome is a community of microorganisms that operate as a “hidden organ” to regulate healthy immune function and other beneficial effects. Recent studies have assessed the relationship between the gut microbiome and heart disease. Our work is a critical evaluation of these findings. The field of microbiome research is rapidly evolving and known biases exist. Reassessment using modern best practices and available databases can clarify the relationship between heart disease and the gut microbiome. This work may aid future …

The Effect Of Implementing Behavioral Counseling For Elevated Ldl Levels, Blake L. Hansen

Evidence-Based Practice Project Reports

Hyperlipidemia is a key risk factor in cardiovascular mortality, and is prevalent in approximately 38% of American adults (CDC, 2022b). Cholesterol levels are intensified by unhealthy lifestyle choices, which means a change in lifestyle behaviors could prevent cardiovascular related deaths (WHO, 2022). The PICOT question for this project was: In adults aged 20 years or older in the primary care setting who have elevated low-density lipoprotein (LDL) levels (P), does the implementation of behavioral counseling on lifestyle modifications (I) compared to current practice (C) decrease LDL levels (O) over a 10- to 12- week period (T)? Fourteen participants from a …

Columbia Chronicle (05/02/2023), Columbia College Chicago

Columbia Chronicle

Student newspaper from May 2, 2023 entitled The Columbia Chronicle. This issue is 20 pages. Cover story: "The DEI Issue". Editor-in-Chief: Olivia Cohen.

(Pro)Renin Receptor And Its Soluble Form In Metabolic Dysfunction: Friend Or Foe?, Gertrude Arthur

Journal of Pharmacology & Nutritional Sciences

(Pro)renin receptor is component of the renin angiotensin system which has been shown to be involved in several physiological and pathophysiological processes including blood pressure regulation and hypertension, water and electrolyte balance, kidney injury, obesity, and metabolic dysfunction. Enzymatic cleavage of prorenin receptor produces soluble prorenin receptor which can also activate the renin angiotensin system stimulate similar pathophysiological process like its full form receptor. This review explores findings on the role of prorenin receptor and soluble prorenin receptor in metabolic dysfunction and discusses the conflicting findings on soluble prorenin receptor in metabolic dysfunction.

Self‑Objectification During The Perinatal Period: The Role Of Body Surveillance In Maternal And Infant Wellbeing, Lauren M. Laifer, Olivia R. Maras, Gemma Sáez, Sarah Gervais, Rebecca L. Brock

Department of Psychology: Faculty Publications

Pregnancy represents a unique time during which women’s bodies undergo significant physical changes (e.g., expanding belly, larger breasts, weight gain) that can elicit increased objectification. Experiences of objectification set the stage for women to view themselves as sexual objects (i.e., self-objectification) and are associated with adverse mental health outcomes. Although women may experience heightened self-objectification and behavioral consequences (such as body surveillance) due to the objectification of pregnant bodies in Western cultures, there are remarkably few studies examining objectification theory among women during the perinatal period. The present study investigated the impact of body surveillance, a consequence of self-objectification, on …

State-Level Macro-Economic Factors Moderate The Association Of Low Income With Brain Structure And Mental Health In U.S. Children, David G Weissman, Mark L Hatzenbuehler, Mina Cikara, Deanna M Barch, Katie A Mclaughlin

2020-Current year OA Pubs

Macrostructural characteristics, such as cost of living and state-level anti-poverty programs relate to the magnitude of socioeconomic disparities in brain development and mental health. In this study we leveraged data from the Adolescent Brain and Cognitive Development (ABCD) study from 10,633 9-11 year old youth (5115 female) across 17 states. Lower income was associated with smaller hippocampal volume and higher internalizing psychopathology. These associations were stronger in states with higher cost of living. However, in high cost of living states that provide more generous cash benefits for low-income families, socioeconomic disparities in hippocampal volume were reduced by 34%, such that …

Macronutrient Composition Of Sea Otter Diet With Respect To Recolonization, Life History, And Season In Southern Southeast Alaska, Nicole Laroche, Sydney King, Emily Fergusson, Ginny Eckert, Heidi Pearson

Faculty, Staff, and Students

The sea otter (Enhydra lutris) population of Southeast Alaska has been growing at a higher rate than other regions along the Pacific coast. While good for the recovery of this endangered species, rapid population growth of this apex predator can create a human-wildlife conflict, negatively impacting commercial and subsistence fishing. Previous foraging studies throughout the sea otter range have shown they will reduce invertebrate prey biomass when recolonizing an area. The goal of this study was to examine and quantify the energy content of sea otter diets through direct foraging observations and prey collection. Our study area, Prince of Wales …

Organ Localization And Detection In Sow’S Using Machine Learning And Deep Learning In Computer Vision, Iyad Almadani

Electronic Theses and Dissertations Archive

The objective of computer vision research is to endow computers with human-like perception to enable the capability to detect their surroundings, interpret the data they sense, take appropriate actions, and learn from their experiences to improve future performance. The area has progressed from using traditional pattern recognition and image processing technologies to advanced techniques in image understanding such as model-based and knowledge-based vision. In the past few years there has been a surge of interest in machine learning algorithms for computer vision-based applications. Machine learning technology has the potential to significantly contribute to the development of flexible and robust vision …

Relational Connections For Youth Aging Out Of Foster Care: A Policy Content Analysis, Heather Miller

Social Work Doctoral Dissertations

Social work professionals and policymakers are faced with the dilemma of older youth exiting foster care each year with poor outcomes, lacking resources and supports that make successful transitions a challenge. Research suggests that youth who have a supportive relationship with a consistent and trusted adult to help navigate the transition to adulthood supports a youth’s successful transition from care. The Federal John H. Chafee Foster Care Program for Successful Transition to Adulthood, initially birthed from the Foster Care Independence Act of 1999 and revised through the Family First Prevention Services Act of 2018, provides states with funding and guidance …

Adiposity-Associated Atrial Fibrillation: Molecular Determinants, Mechanisms, And Clinical Significance, Monika Gawałko, Arnela Saljic, Na Li, Issam Abu-Taha, Thomas Jespersen, Dominik Linz, Stanley Nattel, Jordi Heijman, Anke Fender, Dobromir Dobrev

Faculty, Staff and Students Publications

Obesity is an important contributing factor to the pathophysiology of atrial fibrillation (AF) and its complications by causing systemic changes, such as altered haemodynamic, increased sympathetic tone, and low-grade chronic inflammatory state. In addition, adipose tissue is a metabolically active organ that comprises various types of fat deposits with discrete composition and localization that show distinct functions. Fatty tissue differentially affects the evolution of AF, with highly secretory active visceral fat surrounding the heart generally having a more potent influence than the rather inert subcutaneous fat. A variety of proinflammatory, profibrotic, and vasoconstrictive mediators are secreted by adipose tissue, particularly …

Utilization Of Cellulose Symbiotic Culture Of Bacteria And Yeast (Scoby) With Sweet Tea Media As Methylene Blue And Brilliant Green Biosorbent Material, Leonard Mateus Sigiro, Ahmad Maksum, Donanta Dhaneswara

Journal of Materials Exploration and Findings

The cellulose from Symbiotic Culture of Bacteria and Yeast (SCOBY) can be used as a biosorbent for dye adsorption, such as Methylene Blue and Brilliant Green. This study used sweet tea with a 6% of sugar concentration and 14 days of fermentation time to synthesize biosorbent material from SCOBY. The results from this synthesis are then characterized using FTIR, SEM, and BET. From the result of characterization, it was found that SCOBY has pores formed from cellulose. The results of the average pore size are 1.5976nm with a pore volume of 0.229cc/g, while the specific surface area is 143.244m2/g. The …

Microbial Biofortification: A Sustainable Solution To Feed 10 Billion People, Perrin Thompson, Kathryn Tschida

Celebrating Scholarship and Creativity Day (2018-)

No abstract provided.

Effect Of High Fat Vs High Sugar Diet On Mtor Signaling Pathway In Skeletal Muscle Of Male And Female Mice, Zereque Powell

Electronic Theses and Dissertations Archive

Background: Obesity and MetS has been shown to negatively impact protein synthesis rates. Objective: Determine the effects of sex and high fat/high sugar diets on mTOR signaling pathways. Methods: 15 male and 15 female wild type C57BL/6 mice were randomized into 3 groups: High Fat (45% fat), High Sugar (60% carb) and Control. While continuing diets, body weight and body composition were monitored. Following sacrifice, muscles were examined for changes in the mTOR signaling pathway. Results: Mice consuming the HF diet had the highest levels of weight gain. Females expressed higher levels of expression of P-AMPK. Levels of REDD1 were …

Evaluating Item Bias And Equitability Of The Pediatric Quality Of Life Inventory- Diabetes Module 5 Item Version Amongst Income And Racially Diverse Youth Living With Type 1 Diabetes, Kasey Harry

Electronic Theses and Dissertations Archive

Type 1 Diabetes (T1D) is one of the most common chronic diseases among children in the United States, affecting around 244,000 children and adolescents. In 2014–2015 around 18,200 youth were diagnosed with T1D. T1D requires youth to participate in complex and burdensome health behaviors that can affect health-related quality of life (HRQoL). Measures such as the Pediatric Quality of Life Inventory- Diabetes Module Version 3.2 (PedsQL-DM) are used to determine how T1D has influenced youth and caregivers’ daily lives. Recently, a 5-item version of the Pediatric Quality of Life Inventory- Diabetes Module (PedsQL-DMSF5) was developed; however, it is presently unclear …

Engaging The Vulnerable: Health Literacy For Children Combating Non Communicable Diseases In Sub Saharan Africa, A Review, Madireng Monyela

Library Philosophy and Practice (e-journal)

Background: Instilling health literacy in children could reduce the chances of poor health behaviours and non-communicable diseases (NCDs). Good childhood health literacy has been associated with routinely having a healthier diet, as well as a better understanding and use of nutritional information on foods and drinks. Building resilience in childhood through health literacy programmes can also have a positive impact on psychological health and well-being across the life course, and reducing the severity of depression experienced in adulthood among other diseases.

Objectives: The objectives of the study were to find out how health literacy is offered to children in sub-Saharan …

San Salvador Community Garden Initiative, Jillian Saraney, Emory Evans, Abbie Woodson, Taylor Yates

UTC Spring Research and Arts Conference

The San Salvador Community Garden Initiative is a project intended to address chronic disease prevalence and nutrition security on a San Salvador, Bahamas. This project contains data analysis, soil microbial analysis, and a project overview.

“Your Body Is For You”: Possibilities For Size Acceptance, Criticality, And Social-Emotional Wellness In Upper Elementary English Language Arts Education, Veronica B. Walton

Graduate Student Independent Studies

This Integrated Master’s Project explores how body image literature can be used in upper elementary classrooms (grades 3 to 5) to support critical literacy and psychosocial development, and vice-versa. Using the approaches Health at Every Size® (HAES), affect theory, and critical literacy, I propose a new analytical framework for thinking about weight stigma and children’s self-image through the lens of literature. There is a growing presence of fiction and nonfiction books that address weight stigma and center children’s experiences of their bodies, and incorporating these books into literacy/English Language Arts (ELA) curricula can help educators shape their classrooms into spaces …

Dynamic Transcriptomic Responses Of Circulating Immune Cells In Response To Subsequent Days Of Exercise Heat Stress, Soohyun Oh

University Scholar Projects

Acute exercise and chronic training have diverse effects on immune function that are still not well understood. There are remaining questions about how an acute bout of exercise, competition, or repeated training over a period affects an individual’s immune defense system. In a related study, there is evidence that acute exercise may serve as an adjuvant to enhance response to immune function as well as contradicting evidence, including our preliminary data (unpublished). Understanding the fundamental function and gene expression of circulating immune cells in response to acute exercise and in various contexts such as heat stress is critical in understanding …

Polar Convex Programming: A New Paradigm For Nonlinear Optimization, Lilia Benakkouche, Blake Whitman, Baha Alzalg

Applied Mathematics & Information Sciences

In this paper, our central notions of analysis are convexity and betweenness. These concepts are given from the viewpoint of conceptual spaces and are specified in relation to the coordinates of a polar system. We introduce and study a problem that seeks to optimize a polar convex objective subject to polar convex constraints, which we refer to as the polar convex programming problem. We utilize a geometric methodology to solve the two-dimensional version of this optimization problem. Our interpretation of the approach is inspired by the classical graphical method for linear optimization problems. To the best of our knowledge, this …

Himmelfarb Headlines - May/June 2023, George Washington University, Himmelfarb Health Sciences Library

Himmelfarb Headlines (2009 - present)

News, information, and resources relating to Himmelfarb Library that is of interest to patrons.

The Role Of Fto, A Human Rna Demethylase In Perennial Grass Development And Abiotic Stress Responses, Andrew Fiorentino, Qian Hu, Xiaotong Chen, Zhaohui Chen

Honors College Theses

The integration of the human fat mass and obesity associated (FTO) gene into turfgrass is a novel approach at improving cell proliferation and abiotic stress resistance. The FTO protein is an RNA demethylase responsible for epigenetic regulation of the genome. In related rice, the gene is associated with increased crop yield, tiller number, and aerial biomass. It is proposed to work via demethylation of repeat RNA associated with chromatin remodeling, causing widespread transcriptional activation. In this study, the feasibility of using FTO for plant trait modification in perennial grasses is being investigated. Potentially transformed embryogenic calli of creeping bentgrass with …

Food And Sovereignty: Enacting Mino-Bimaadiziwin In Gaa-Waabaabiganikaag, Zaryn Prussia

Anthropology Honors Projects

No abstract provided.

Southern Adventist University Commencement Program May 2023, Southern Adventist University

Commencement Programs

Program for Southern Adventist University Spring 2023 graduation. The commencement service took place on May 7, 2023 at 9 am and 1 pm in Iles Physical Education Center.

Ambulance Deserts: Geographic Disparities In The Provision Of Ambulance Services [Chartbook], Yvonne Jonk Phd, Carly Milkowski Mph, Zachariah Croll Mph, Karen Pearson Mlis, Ma

Emergency Medical Services (EMS)

This chartbook begins with a broad overview of ambulance services including common types of organizational structure(s) and workforce and reimbursement issues. The methods section provides our definition of ambulance deserts and describes how ambulance deserts are illustrated in the national and state maps. The results section begins with an overall description of the prevalence of ambulance deserts in rural and urban counties across the 41 states for which data were available at the time, and the variation in the percent of people living in ambulance deserts across the four census regions. States are ranked in terms of the percent of …

Clemson University Women Trailblazers, A. M. Alexander, J. W. Harris

Clemson University Women Trailblazers

No abstract provided.

The Role Of Cytochrome P450 2e1 In Hepatic Ischemia Reperfusion Injury And Reactive Oxygen Species Formation, Nouf Alwadei

Pharmaceutical Sciences (PhD) Dissertations

The mechanisms of hepatic ischemia/reperfusion (I/R) injury, which occurs during liver transplantation or surgery, are poorly understood. The central pathophysiological phenomenon of this injury is the formation of reactive oxygen species (ROS). Recent studies suggest that P450 enzymes may contribute to ROS generation, which may occur through their uncoupling and/or release of heme and iron after their degradation. Among P450 enzymes, CYP2E1 is unique because it is considered a leaky enzyme, producing significant ROS through uncoupling in the absence of substrates, accelerating its own degradation and reducing its half-life. In this dissertation, we generated and characterized a HepG2 cell line …

Medium-To Long-Term Socioeconomic Impact Of Covid-19 In Arab Countries, 2022, Nevin Wanis, Farouk Shoaib, Mohamed Naguib

Journal of Statistics Applications & Probability

COVID-19 pandemic is impacting institutions around the world. Its scope and economic dimensions pinpoint that it poses a major threat to achieving the UN Sustainable Development Goals (SDGs). The main objective of thisresearch is to discuss how the coronavirus pandemic may influence the SDGsand affect their implementation. The methods used entail an analysis of lite rature, observations and an assessment of current world trends and applied UNDP method to Arab countries. Methodology/approach—the motivation behind this research is to assess the impacts of the COVID-19 pandemic. Todo so, as a first step, we conduct an initial factual analysis to identify the …