Imidazole Propionate As A Potential Modulator Of T-Cell Function, Chinanu Gubor

Electronic Theses and Dissertations Archive

Research has shown the metabolic role and therapeutic potential of the gut microbiome in modulating health and disease states. Microbial metabolites are known to be involved in various metabolic functions throughout the body. The purpose of this study was to determine if the microbial metabolite imidazole propionate, shown to be increased in obesity and type II diabetes, has an effect on key human T-cell functions. Two fasted blood samples were collected from 10 human subjects. PBMCs were isolated, and a subset were stimulated in the presence of ImP. After staining for cell-surface antigens and intracellular cytokines, flow cytometry analysis was …

Song’S Site At Los Angeles Eco-Village Redevelopment, Kendall Gilbert, Marina Rios, Kristin Hernandez, Gianna Morelli

Honors Thesis

The Los Angeles Eco-Village (LAEV) is a co-op housing community, located in Koreatown, focused on building sustainable and economically cooperative living in an urban environment. The purpose of this project is to transform a property recently acquired by the LAEV, called Song’s, into a multipurpose community hub. The project design goals established with LAEV founder and community members, include cultivating new highly sustainable and resilient ideas on urban living and incorporating educational elements that inspire the community and visitors to live more sustainably. This project proposes three design elements to improve the community use of the newly acquired Song’s at …

Redesigning Nasogastric Feeding Tubes To Prevent Dislodgement, Sydney Ruth Rester, Shelby Lynn Berry

Honors Theses

Seniors at the University of Mississippi studying biomedical engineering complete a senior project that seeks to solve a problem in healthcare. Our team, composed of Sydney Rester, Shelby Berry, Andrew Ulmer, and Alex Bromley, sought to improve care associated with nasogastric feeding tubes. We identified two major problems: clogging and tube dislodgement. To address the problem of dislodgement, the team crafted a new feeding tube design with a balloon attachment. The attachment prevents a patient from pulling the feeding tube out and keeps the tube from dislodging due to normal patient movement. We further determined that our tube should be …

Live Well, Eat Well, Be Active With Diabetes Curriculum Improves Type 2 Diabetes Management, Lauren Amaya, Dana Baldwin, Kathy Enyart, Arleen James, Tommie M. James, Penny R. King, Jan Maples, Lindy Peterman, Sara Randolph, Dea Rash, Kelsey Ratcliff, Joy Rhodes, Jessica Riggin, Janis Risley, Danette Russell, Janice Hermann

Journal of Extension

Type 2 diabetes is a complex disease with several modifiable lifestyle factors. The Extension ‘Live well, Eat well, be Active with Diabetes’ curriculum provides four 90-minute lessons teaching individuals to live well, eat well, and be active with diabetes. Fourteen Extension educators implemented and evaluated the curriculum with 107 participants. Participants reported the program helped them feel better able to take care of their health. We observed significant differences in participants’ retrospective pre and post ‘Live well,’ ‘Eat well’ and ‘be Active’ total scores. Extension has a unique opportunity to educate individuals so they may better manage their diabetes.

Fafsa Completion: Considerations For An Extension-Led Statewide Nudge Campaign, Portia L. Johnson, Kacee Ross, Emily Hines

Journal of Extension

Eight U.S. states have enacted legislation that mandates high school seniors to act on the Free Application for Federal Student Aid (FAFSA) before graduation. At least 10 other states are considering implementing similar FAFSA requirements. While proponents of the law believe it will affect postsecondary education and the workforce positively, dissenters argue that the policy is an unfunded mandate that taxes students and parents without offering adequate resources. This article synthesizes existing literature related to policy-related nudge campaigns to provide an Extension-led, cost-effective strategy to achieve the FAFSA mandate’s goal and improve citizens’ FAFSA completion behavior.

Strategies To Advance Antiracist Programs: Why They Matter, Scott D. Scheer

Journal of Extension

The U.S. Extension system has been aware for many years of the racial inequality and disparities present today and throughout U.S. history. Even though there have been concerted efforts in Extension to improve racial equity and inclusion, much work remains. A dual approach is proposed for Extension to focus both internally (program planners) and externally (program participants) to bring about antiracist programs that are inclusive and racially equitable. Research-based strategies are discussed for both domains of program planners (e.g., implicit bias training) and program participants (e.g., reach people of color through culturally relevant curricula).

Redesigning Nasogastric Feeding Tubes To Prevent Dislodgement, Shelby Lynn Berry, Sydney Ruth Rester

Honors Theses

Seniors at the University of Mississippi studying biomedical engineering complete a senior project that seeks to solve a problem in healthcare. Our team, composed of Sydney Rester, Shelby Berry, Andrew Ulmer, and Alex Bromley, sought to improve care associated with nasogastric feeding tubes. We identified two major problems: clogging and tube dislodgement. To address the problem of dislodgement, the team crafted a new feeding tube design with a balloon attachment. The attachment prevents a patient from pulling the feeding tube out and keeps the tube from dislodging due to normal patient movement. We further determined that our tube should be …

Igfbp2 Expressing Midlobular Hepatocytes Preferentially Contribute To Liver Homeostasis And Regeneration, Yu-Hsuan Lin, Yonglong Wei, Qiyu Zeng, Yunguan Wang, Chase A Pagani, Lin Li, Min Zhu, Zixi Wang, Meng-Hsiung Hsieh, Natasha Corbitt, Yu Zhang, Tripti Sharma, Tao Wang, Hao Zhu

Faculty, Staff and Student Publications

Although midlobular hepatocytes in zone 2 are a recently identified cellular source for liver homeostasis and regeneration, these cells have not been exclusively fate mapped. We generated an Igfbp2-CreER knockin strain that specifically labels midlobular hepatocytes. During homeostasis over 1 year, zone 2 hepatocytes increased in abundance from occupying 21%-41% of the lobular area. After either pericentral injury with carbon tetrachloride or periportal injury with 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC), IGFBP2+ cells replenished lost hepatocytes in zones 3 and 1, respectively. IGFBP2+ cells also preferentially contributed to regeneration after 70% partial hepatectomy, as well as liver growth during pregnancy. Because IGFBP2 labeling increased …

The Bias Of New Mexico Nurses In A Residency Program Toward People Experiencing Homelessness, Tolulope Kabir Fijabi

Doctor of Nursing Practice Scholarly Projects

ABSTRACT

There is growing evidence that healthcare workers do not provide equivalent levels of care to patients of different social groups. This group includes the population of people experiencing homelessness and the number continues to grow simultaneously across U.S. Studies have also shown that the poor and the marginalized experiences disappointment in the healthcare industry due to negative attitudes such as stereotyping, bias, and prejudice from healthcare providers limiting them from accessing care when necessary. With growing research on the influence of the experience of trauma among people experiencing homelessness, there is a lack of trauma-informed services as it relates …

Key Takeaways For Knowledge Expansion Of Early-Career Scientists Conducting Transdisciplinary Research In Energetics And Cancer (Trec): A Report From The Trec Training Workshop 2022, Che-Pei Kung, Meghan B. Skiba, Erika J. Crosby, Jessica Gorzelitz, Mary A. Kennedy, Bethany A. Kerr, Yun Rose Li, Sarah Nash, Melanie Potiaumpai, Amber S. Kleckner, Dara L. James, Michael F. Coleman, Ciaran M. Fairman, Gloria C. Galván, David O. Garcia, Max J. Gordon, Mathilde His, Lyndsey M. Hornbuckle, So-Youn Kim, Tae-Hyung Kim, Amanika Kumar, Mélanie Mahé, Karen K. Mcdonnell, Jade Moore, Sangphil Oh, Xinghui Sun, Melinda L. Irwin

Pathology Research and Scholarship

The overall goal of the annual Transdisciplinary Research in Energetics and Cancer (TREC) Training Workshop is to provide transdisciplinary training for scientists in energetics and cancer and clinical care. The 2022 Workshop included 27 early-to-mid career investigators (trainees) pursuing diverse TREC research areas in basic, clinical, and population sciences. The 2022 trainees participated in a gallery walk, an interactive qualitative program evaluation method, to summarize key takeaways related to program objectives. Writing groups were formed and collaborated on this summary of the 5 key takeaways from the TREC Workshop. The 2022 TREC Workshop provided a targeted and unique networking opportunity …

Dimeric P53 Mutant Elicits Unique Tumor-Suppressive Activities Through An Altered Metabolic Program, Jovanka Gencel-Augusto, Xiaoping Su, Yuan Qi, Elizabeth M Whitley, Vinod Pant, Shunbin Xiong, Vrutant Shah, Jerome Lin, Encarnacion Perez, Marta L Fiorotto, Iqbal Mahmud, Abhinav K Jain, Philip L Lorenzi, Nicholas E Navin, Ellen R Richie, Guillermina Lozano

Faculty, Staff and Student Publications

Cancer-related alterations of the p53 tetramerization domain (TD) abrogate wild-type (WT) p53 function. They result in a protein that preferentially forms monomers or dimers, which are also normal p53 states under basal cellular conditions. However, their physiologic relevance is not well understood. We have established in vivo models for monomeric and dimeric p53, which model Li-Fraumeni syndrome patients with germline p53 TD alterations. p53 monomers are inactive forms of the protein. Unexpectedly, p53 dimers conferred some tumor suppression that is not mediated by canonical WT p53 activities. p53 dimers upregulate the PPAR pathway. These activities are associated with lower prevalence …

Qualitative Analysis Of The Expanded Food And Nutrition Education Program’S 24-Hour Dietary Recall, Serena M. Fuller, Josh A. Phelps, Susan Baker, Jennifer Walsh

Journal of Extension

The Expanded Food and Nutrition Education Program (EFNEP) uses a group 24-hour dietary recall (Gr24HDR) to measure changes in diet quality. Participant perceptions of the tool can guide implementation practices used by EFNEP Extension staff. Focus group (FG) sessions were conducted in five states and transcripts analyzed following a framework analysis approach. According to FG participants, a range of factors, condensed into six themes with potential interactions, influence Gr24HDR including implementation processes and community settings. Findings inform overarching considerations EFNEP staff may take when collecting Gr24HDR data in the field to improve the evaluation process for participants.

Assessing The Snap Consumer Environment At Farmers Markets, Gabrielle C. Young, Sarah Misyak, Meredith Ledlie Johnson, Natalie E. Martin, Elena Serrano

Journal of Extension

The SNAP at Farmers Market Environmental Assessment was developed as a tool for market managers to examine SNAP participant accessibility for redeeming SNAP benefits at farmers markets. By completing the SNAP at Farmers Market Environmental Assessment, the tool can serve as a guide for providing practical next steps for market improvement. Extension practitioners and researchers, including SNAP-Ed staff, can use the assessment tool to support policy, systems, and environment change efforts that promote access to local, high-quality foods by SNAP consumers, the redemption of SNAP benefits, and potentially increased sales at farmers markets.

An Economic History Of Ellis County, Kansas, Danielle Knoll, Alison Helget, Matthew Lamunyon, Colton Wagner, Daniel Robert Mcclure

Academic Leadership Journal in Student Research

Like many American rural communities in the second decade of the twenty-first century, Ellis County faces tough decisions regarding economic development, population growth, and sustainable strategies. This paper examines the history of the region since the early twentieth century, tracing the evolution of various industries—from oil to farming—and the different ways the community responded to the area and nation’s economic shifts. This “big picture” view of Ellis County operates as a starting point for strategizing paths forward for area residents.

Low-Load X High-Load Resistance Exercise: Greater Cell Swelling After A Training Session, Gabriel Agentilho, Erick Lucena, Luis Felipe M. Teixeira, Vanessa Boas, Isadora Ribeiro, Renato Barroso, Brad Schoenfeld, Marco Uchida

International Journal of Exercise Science

International Journal of Exercise Science 16(3): 513-524, 2023. Cell swelling caused by resistance training is proposed to provide an anabolic stimulus for muscle growth and it is believed that these effects are heightened with the use of low loads. The purpose of this study was to compare the acute effects of two volume-equated resistance training (RT) protocols, low-load (LL) versus high-load (HL), on elbow flexor muscles thickness, arm circumference, and blood lactate concentration in well-trained individuals. Eight resistance-trained males performed the following two RT protocols involving unilateral elbow flexion of the dominant arm: i) LL, four sets with 50% 1 …

Review Of Telemedicine Use As It Expands Since The Covid-19 Pandemic, Michael P. Perra, Frederick J. Goldstein

Research Day

INTRODUCTION: As new technology advances and the world becomes increasingly connected, medical care and physician-patient interactions have changed. Telemedicine, though present in different forms for many decades, has grown, and its use is changing at a faster-than-ever pace. The COVID-19 pandemic highlighted the utility of different telemedicine platforms and has led to an expansion in its capabilities.

OBJECTIVES: To explore the evolution of telemedicine, its multiple functions, and how this technology has continued to develop since the COVID-19 pandemic in various medical specialties.

METHODS: PubMed was used to assess published studies that either incorporated telehealth resources in their research or …

An Overview Of Viruses And The Infamous Sars-Cov-2, Jake Sun

The Confluence

Background information on viruses is first presented which include topics like evolution, ecology, history, identification, structure, and application. The novel SARS-CoV-2, which causes COVID-19, pandemic originated in Wuhan, China in December 2019. Millions of people were infected with the virus in a short time period causing urgent concern worldwide. The purpose of this review is to provide a brief and general understanding of the SARS-CoV-2 to increase awareness and actions toward preventive measures. COVID-19 is a (+) ssRNA spherical enveloped virion that causes primarily respiratory illnesses. The S protein interacts with ACE-2 receptors on the host cell to gain entry …

The Myth Of Wellness: Deconstructing High, Contemporary Black Maternal Mortality Rates In The United States, Inaara Sultanali '23

Senior Scholarly and Creative Symposium

Maternal mortality is widely acknowledged as one of many general indicators of overall health of a population, of status of women in society, and of functioning of the health system (World Health Organization [WHO], 2001). The United States, among one of the most high-income countries, ranks near the top in maternal mortality and the trend is increasingly exacerbating (Association of American Medical Colleges [AAMC], 2022). There are stark racial disparities within the United States’ maternal mortality rates; Black women in the United States are three to four times more likely to die from a pregnancy-related death than their White counterparts …

Volume 4, Chapter 1-24: Aquatic And Wet Marchantiophyta, Class Marchantiopsida: Marchantiaceae, Part 2, Janice M. Glime

Bryophyte Ecology Subchapters

No abstract provided.

Spartan Daily, May 3, 2023, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2023

Volume 160, Issue 39

Usa V. Miriam Zughbi

2023 Decisions

USDC for the District of New Jersey

Funding To Advance Sustainability Projects And Action Across Campus And Beyond, Sustainability Institute

Sustainability Institute Blog

No abstract provided.

Why Understanding Food Choice Is Crucial To Transform Food Systems For Human And Planetary Health, Krystal K. Rampalli, Christine E. Blake Ph.D., Rd, Edward A. Frongillo Ph.D., Joseph Montoya

Faculty Publications

What, how and why people eat has long been understood to be important for human health, but until recently, has not been recognised as an essential facet of climate change and its effects on planetary health. The global climate change and diet-related health crises occurring are connected to food systems, food environments and consumer food choices. Calls to transform food systems for human and planetary health highlight the importance of understanding individual food choice. Understanding what, how and why people eat the way they do is crucial to successful food systems transformations that achieve both human and planetary health goals. …

The Association Of Dementia Caregiver Employment With Sleep Quality: Does Being A Spouse Matter?, Jasnoor Kaur

Honors College Theses

Background: Family caregivers for a person living with dementia (PLwD) can experience stress and burden which may relate to health consequences such as poor sleep quality. This study aimed to 1) examine the association between caregiver employment status and sleep quality and 2) understand how this association may be moderated by the relationship of the caregiver to the PLwD.

Methods: A sample of primary caregivers for a PLwD (N = 100) were interviewed in person in 2017. A linear regression with the Pittsburgh Sleep Quality Index (PSQI) global score as the outcome and employment status as the key predictor, and …

A Multimodal Smartphone Application Intervention To Achieve Target Weight Goals In Overweight Adult Diabetics, Michael Thomas Schwuchow

Evidence-Based Practice Project Reports

Obesity is the leading risk factor for developing type 2 diabetes mellitus (American Diabetes Association, 2022). Diabetes mellitus (DM) and obesity put individuals at higher risk for developing heart disease, stroke, and hypertension, therefore, it is essential to properly manage both conditions. The purpose of this project is to determine if the implementation of an evidence-based weight loss intervention, MyFitnessPal© will result in reduction in body mass index (BMI) and lower hemoglobin A1c (HbA1c) levels in overweight adults with DM. A comprehensive literature search of six databases, hand searching, and citation chasing yielded 13 pieces of moderate to high quality …

Gnsi Decision Brief: Hunger As A Weapon, Tad Schnaufer, David Himmelgreen

GNSI Decision Briefs

Overview

Maslow’s hierarchy of needs places physiological needs as the foundation of all others.i The needs of food, water, and shelter are referred to as objects indispensable to survival (OIS). A person will think of little else until these basic needs are met, hence the power OIS have over populations. The concept of hunger as a weapon dates to the beginning of written history with Homer’s Iliad describing the siege of Troy. In war, military leaders often consider foodstuffs as it relates to their war effort while analyzing ways to use this basic need against their foe. As the quote …

Funding To Advance Sustainability Projects And Action Across Campus And Beyond, Sustainability Institute

Sustainability Institute Blog

No abstract provided.

A Probabilistic Exploration Of Food Supplementation And Assistance, Logan Mattingly

Honors College Theses

Food insecurity is a stark threat that grips our country and affects households throughout our country. Dietary insufficiency manifests itself in ways that affect health and public safety. According to researchers, individuals who suffer from food insecurity have a higher risk of aggression, anxiety, suicide ideation and depression. These problems tend to occur unequally distributed among those households with lower income. In this work, an exploratory analysis within these data sets will be performed to examine the socio-economic, biographical, nutritional, and geographical principal components of food insecurity among survey participants and how the US Supplemental Nutrition Assistance Program (SNAP) effects …

Growth, Morphological, And Biochemical Responses Of Four Native Species To Salinity Stress, Asmita Paudel, Youping Sun

Plants, Soils, and Climate Faculty Publications

Native plants are of great value in landscape maintenance. Despite their importance in the landscape, the salt tolerance of most native plants has received little attention. The present research was designed to assess morphological, physiological, and biochemical responses of four Utah-native plants [Arctostaphylos uva-ursi (kinnikinnick), Cercocarpus ledifolius (curl-leaf mountain mahogany), Cercocarpus montanus ‘Coy’ (alder-leaf mountain mahogany), and Shepherdia ×utahensis ‘Torrey’ (hybrid buffaloberry)] at different salinity levels. Each species was irrigated with a nutrient solution at an electrical conductivity (EC) of 1.2 dS·m^-1 (control) or saline solutions at ECs of 5.0 or 10.0 dS·m^-1 for 8 …

Secondary Data Analysis: Predictors Of Employment Among Young Adults With Cerebral Palsy, Eduardo Santos Del Rosario

Theses & Dissertations

Young adults with cerebral palsy have lower employment rates as compared to young adults in general, as they may be confronted with complex interactions between cognitive delays, physical impairments, activity limitations, participation challenges, and personal and/or societal barriers as they progress to adulthood. These challenges are clear, the solutions, less so. Understanding the predicting factors of employment is vital to future generations of this population. The purpose of this study is to identify predictor variables and examine the relationship of those variables to employment. It has explored existing Rehabilitation Services Administration (RSA-911) data through the lens of the International Classification …