Digital Commons Network^™

The Relationship Between Nutrition, Gut Dysbiosis, And Pediatric Sickle Cell Pain Outcomes: A Pilot Study, Chinenye R. Dike, Corrine K. Hanson, Dele Davies, Stephen Obaro, Fang Yu, James L. Harper, Helen Grace, Jeffrey Lebensburger, Chittalsinh M. Raulji, Jihyun Ma, Peter Mannon

Journal Articles: Pediatrics

BACKGROUND: Nutritional deficiencies are prevalent in sickle cell disease (SCD) and may be associated with worse pain outcomes. Gut dysbiosis has been reported in patients with SCD and may contribute to both nutritional deficiencies and pain.

OBJECTIVES: We tested the association of nutrition, fat-soluble vitamin (FSV) deficiency, and gut microbiome composition on clinical outcomes in SCD. Second, we measured the association between diet and exocrine pancreatic function on FSV levels.

METHODS: Using case control design, we enrolled children with SCD (n = 24) and matched healthy controls (HC; n = 17, age, sex, race/ethnicity). Descriptive statistics summarized demographic and clinical …

Targeting Parental Behavior: Contingency Contracting To Increase Parental Competence And Adherence, Sara Clasky Richardson

Theses and Dissertations

The purpose of this study was to investigate the impact of using behavior contracts specifically targeting parental behavior and providing reinforcing consequences for the parent’s behavior on parental adherence in implementing behavior contracts to address their child’s behavior problems. Parents used identical procedures to implement behavior contracts with their children to address their child’s noncompliance and associated problem behavior. A secondary purpose of this study was to determine parent perceptions about the impact their use of behavior contracts had on the behavior of their children.

This study used a multiple baseline across participants design to measure the effectiveness of a …

A Mixed-Method Study On Social Media’S Role In The Health Decision-Making Practices Of Black Millennial Women In South Florida, Sashah Damier

Theses and Dissertations

The purpose of this research study was to examine health care decision-making practices of Black millennial women in South Florida, based on their social media use. The study contributed to understanding of how cultural components contribute to health care disparities for people of color because health care providers lacked information on how to reach Black millennial women with accurate and helpful information through social media.

The design for the study included a convergent parallel mixed-methods design using a web-based quantitative cross-sectional survey along with embedded qualitative telephone interviews and NVivo software. This mixed-methods methodology provided rich data and new understandings …

Reflections On “Personal Responsibility” After Covid And Dobbs: Doubling Down On Privacy, Susan Frelich Appleton, Laura A. Rosenbury

Scholarship@WashULaw

This essay uses lenses of gender, race, marriage, and work to trace understandings of “personal responsibility” in laws, policies, and conversations about public support in the United States over three time periods: (I) the pre-COVID era, from the beginning of the American “welfare state” through the start of the Trump administration; (II) the pandemic years; and (III) the present post-pandemic period. We sought to explore the possibility that COVID and the assistance programs it inspired might have reshaped the notion of personal responsibility and unsettled assumptions about privacy and dependency. In fact, a mixed picture emerges. On the one hand, …

Fungicide Sensitivity In P. Tritici-Repentis Diverse Population And Phenotyping Of Spelt Wheat For Multiple Diseases, Zunera Shabbir

Electronic Theses and Dissertations

Pyraclostrobin, a QoI fungicide, is extensively used in the management of fungal leaf spot diseases. In this study, 215 P. tritici-repentis isolates collected from wheat fields in South Dakota were evaluated for their sensitivity to Pyraclostrobin. Of 215 isolates, 48 isolates (22%) exhibited insensitivity based on G143A mutation and EC50 values using spore germination assay. Our results indicate reduced sensitivity to insensitivity to pyraclostrobin in some isolates suggesting regular monitoring of the P. tritici-repentis population to QoI fungicides is essential to track the evolution of insensitive population. Spelt wheat (Triticum spelta L.) is an ancient cereal that is gaining small …

Development Of Corn Kernel-Based Biocomposite Films For Food Packaging Applications, Swastika Bera

Electronic Theses and Dissertations

Most of the current and active food packaging resources and methods are nonbiodegradable and nonrenewable therefore harmful to the environment. Due to this, alternate sources of food packaging materials are in high demand. In this study, a bio-composite film has been developed, with Corn kernel powder as fiber reinforcement which is mixed with gelatin, and lignin two biopolymers as the matrix. The effect of Corn Kernel (CK) reinforcement on the Gelatin/Lignin (G/L) matrix on mechanical and barrier properties has been studied. CK has shown great potential as reinforcement to natural polymer, gelatin, and lignin (G/L) for food packaging applications as …

Effects Of Dietary Genistein And Fugacity Modelling In An Aquaculture System, Travis Schaeffer

Electronic Theses and Dissertations

Fish production from aquaculture has continued to grow over the past several decades, with finfishes being fed formulated, fish meal-based diets supporting most of that industry’s growth. However, increased demand and costs, coupled with static volume and erratic supplies of fish meal, has resulted in the use of alternative plant-derived protein sources. A common oilseed protein source is soybean meal (SBM), because of its protein content and amino acid profile; however, it also contains multiple anti-nutritional factors, including phytoestrogens. Phytoestrogens are naturally produced, estrogenmimicking compounds, with isoflavones receiving the most investigation as higher levels of these compounds occur within SBM. …

Federal Nonenforcement At A Crossroads, Zachary Price

Faculty Scholarship

As a novel aspect of “presidential administration”—the president- centered approach to federal governance discussed in a 2001 article by then-Professor and future Supreme Court Justice Elena Kagan—broad federal nonenforcement policies have been a major source of controversy in the past decade. As illustrated by the Obama Administration’s ex- pansive nonenforcement policies relating to marijuana, immigration, and Affordable Care Act implementation, recent presidents have recog- nized nonenforcement’s potential to reshape statutory law to suit an administration’s policy aims. This Article takes stock of this develop- ment as it relates to the past three presidential administrations. While advocating a limited view of …

Effects Of Pregnancy And Lactation On Muscle-Tendon Morphology, Nicole Danos, Marjorie Patrick, Jacob Barretto, Francesca Bilotta, Megan Lee

Biology: Faculty Scholarship

Pregnancy and lactation hormones have been shown to mediate anatomical changes to the musculoskeletal system that generates animal movement. In this study, we characterize changes in the medial gastrocnemius muscle, its tendon and aponeuroses that are likely to have an effect on whole animal movement and energy expenditure, using the rat model system, Rattus norvegicus. We quantified muscle architecture (mass, cross-sectional area, and pennation angle), muscle fiber type and diameter, and Young's modulus of stiffness for the medial gastrocnemius aponeuroses as well as its contribution to Achilles tendon in three groups of three-month-old female rats: virgin, primiparous pregnant, and primiparous …

Changes In The Microbiome Of The Sea Anemone Exaiptasia Diaphana During Bleaching From Short-Term Thermal Elevation, Jamison R. Sydnor, Jamie Lopez, Gordon V. Wolfe, Lisa Ott, Cawa Tran

Biology: Faculty Scholarship

We examined the response of microbial communities in the model sea anemone Exaiptasia diaphana (Aiptasia) to short-term thermal elevation. Through 16S rRNA gene sequencing, we characterized the microbiomes of symbiotic (with algal symbionts) and aposymbiotic (bleached) anemones under ambient (27°C) and heat-stressed (34°C) conditions for 8-10 days, using both replicated endpoint and non-replicated time-course approaches. Consistent with prior studies, we observed a stable abundance of bacteria from the families Alteromonadaceae and Rhodobacteraceae, though with wide variation among individual anemones. We observed that symbiotic state conferred a larger impact on the microbiome than heat stress, implying the microbiome may play a …

Analysis Of Factors Affecting Cross-Boundary Knowledge Mobilization In Agri-Food Supply Chains: An Integrated Approach, Guoqing Zhao, Huilan Chen, Shaofeng Liu, Denis Dennehy, Paul Jones, Carmen Lopez

Plymouth Business School

Agri-food supply chains (AFSCs) link produce from farm-to-fork. Over 80% of businesses operating in AFSCs are small and medium-sized enterprises (SMEs) that lack the necessary resources to make knowledge accessible and usable to other stakeholders. To enhance AFSCs’ performance, we adopt an integrated approach to analyze factors affecting knowledge mobilization (KMob) across boundaries. Thematic analysis of data collected from interviews reveals 11 KMob factors. We apply total interpretive structural modeling (TISM) to identify influential relationships among these factors, and fuzzy cross-impact matrix multiplication applied to classification (MICMAC) to distinguish each factor’s role in the system. Our results complement previous studies …

A Mixed Methods Study Investigating Sources Of Fertility And Reproductive Health Information In The Uk, B. Grace, J. Shawe, J. Stephenson

School of Nursing and Midwifery

No abstract provided.

Air Quality And Mental Health: Evidence, Challenges And Future Directions, Kamaldeep Bhui, Joanne B. Newbury, Rachel M. Latham, Marcella Ucci, Zaheer A. Nasir, Briony Turner, Catherine O'Leary, Helen L. Fisher, Emma Marczylo, Philippa Douglas, Stephen Stansfeld, Simon K. Jackson, Sean Tyrrel, Andrey Rzhetsky, Rob Kinnersley, Prashant Kumar, Caroline Duchaine, Frederic Coulon

School of Biomedical Sciences

Background Poor air quality is associated with poor health. Little attention is given to the complex array of environmental exposures and air pollutants that affect mental health during the life course. Aims We gather interdisciplinary expertise and knowledge across the air pollution and mental health fields. We seek to propose future research priorities and how to address them. Method Through a rapid narrative review, we summarise the key scientific findings, knowledge gaps and methodological challenges. Results There is emerging evidence of associations between poor air quality, both indoors and outdoors, and poor mental health more generally, as well as specific …

Patient-Specific Analysis Of Aortic Hemodynamics And Wall Shear Stresses In Patients Undergoing Pediatric Bariatric Surgery Using 2d Phase-Contrast Mri, Oluwaferanmi S. Akande, Joao Soares, Nathan Hargan, Dr. Uyen Truong, Haeung Kang, David Lanning

UROP Posters

Patient-Specific Analysis of Aortic Hemodynamics and Wall Shear Stresses in Patients Undergoing Pediatric Bariatric Surgery using 2D Phase-Contrast MRI

Feranmi Akande¹ Nathan Hargan² Haesung Kang³ David Lanning³ Uyen Truong⁴ João S. Soares¹

¹ Department of Biomedical Engineering, College of Engineering, Virginia Commonwealth University

² Department of Mechanical & Nuclear Engineering, College of Engineering, Virginia Commonwealth University

³ Department of Cardiology, Children’s Hospital of Richmond, Virginia Commonwealth University

Introduction: Severe obesity among today’s youth is a rising epidemic within the United States. Emerging research has linked childhood obesity with shortened life expectancy and early …

School Attendance Information Or Conditional Cash Transfer? Evidence From A Randomized Field Experiment In Rural Bangladesh, Tomoki Fujii, Christine Ho, Rohan Ray, Abu S. Shonchoy

Research Collection School Of Economics

Low school attendance remains an important challenge in resource-poor settings with cash and information constraints. We compare conditional cash transfer (CCT) treatments with framing variations (gain and loss) against attendance information treatment as interventions to address these constraints in a unified framework. Our randomized evaluation shows CCT treatments increase attendance by 11 percentage points, about half of which is attributable to attendance information. These treatments improve girls’ academic aspirations and reduce early marriage. Daily CCT set at a quarter of local child wage maximizes attendance impact. We highlight the importance of low-cost information technology to boost attendance sustainably and cost-effectively.

Sexual Misconduct Against Female Athletes: Knowledge, Training, And Readiness To Act Of Future Sport Leaders, Mackenzie B. Luikart

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study is to understand the comprehensiveness and effectiveness of current education in sport related degree programs and the impact that has on future and current sport leaders to confront and report sexual misconduct in sport.

A total of 15 participants were selected to participate in this study. The participants for this study include current graduate students pursuing degree programs in either coaching studies or sport management, and graduates of these two programs (within the last five years) who are currently in the workforce in their respective fields. Most participants were white, female, and currently served a …

Implementation Of A Preconception Health Counseling Program, Emily J. Stidham

DNP Projects

Approximately 75 million women in the United States are of reproductive age, 15-44 years old. Among this group of childbearing-aged women, hypertension, diabetes, obesity, and other chronic health conditions are contributing to maternal morbidity, mortality, and poor infant outcomes (Raghuraman & Tuuli, 2021). The current unintended pregnancy rate in the United States is 48%, higher than the global rate of 41% (Ramos, 2019). To improve women’s health and perinatal outcomes, a shift in the paradigm of healthcare should focus on preventative care rather than reactive care. Preconception health counseling (PCHC) with the patient is a primary prevention strategy that allows …

Nutrient Function Over Form: Organic And Inorganic Nitrogen Additions Have Similar Effects On Lake Phytoplankton Nutrient Limitation, Sabrina N. Volponi, Heather L. Wander, David C. Richardson, Clayton J. Williams, Denise A. Bruesewitz, Shelley Arnott, Jennifer A. Brentrup, Hailee L. Edwards, Holly Ewing, Kristen Holeck, Lauren Johnson, Brian S. Kim, Ana M. Morales-Williams, Nisha Nadkarni, Beth C. Norman, Lianne Parmalee, Amy Shultis, Adrienne Tracy, Nicole K. Ward, Kathleen C. Weathers, Courtney R. Wigdahl-Perry, Kiyoko Yokota

All Faculty Scholarship

The concentration of dissolved organic nitrogen (DON) is increasing in many northern hemisphere lakes, yet its use by phytoplankton and fate in the environment seldom have been quantified. We conducted 1 week, in situ, microcosm incubations across 25 lakes in northeastern North America to understand how DON, dissolved inorganic nitrogen (DIN), and dissolved inorganic phosphorus (P) affected phytoplankton biomass. In addition, we tested whether lakes were limited by single macronutrients (N or P) or colimited by both. Phytoplankton biomass in 80% of lakes responded similarly to DON and DIN additions. Of the lakes where N form produced differential responses, the …

The Influences Of The Religious Tradition Of Ramadan On Dietary Intake And Body Composition In Adolescent Athletes: An Evidence-To-Practice Review, Regina A. Duncan, Shannon E. Ryan, Erin M. Watlington, Nancy A. Uriegas, Zachary K. Winkelmann

Clinical Practice in Athletic Training

When participating in the religious tradition of Ramadan, the body is subject to changes that adjust an athlete's regimented dietary intake. The guiding systematic review and meta-analysis were conducted to gather the results of the limited research on the effect of Ramadan observance on body mass, body composition, and dietary intake in adolescent athletes. Data were extracted from two different databases, and a search through several journals exploring body mass and/or body composition and/or dietary intake was conducted. The methodological quality of each study was assessed via QualSyst. No significant differences were found when comparing the body mass, body composition, …

“Bhat Khaiso?”: The Role Of Food In A Bangladeshi Community In The U.S., Jinia Meherin , '23

Senior Theses, Projects, and Awards

No abstract provided.

Healthcare Providers’ Knowledge And Implementation Of Pneumococcal Vaccination Recommendations, Lara Blake, Pam White

MSN Research Projects

Streptococcal pneumoniae is a vaccine preventable disease but remains a leading cause of disease and death in the United States. In 2016, Streptococcal pneumoniae was responsible for 1.2 million deaths in over 195 countries. The illness is attributed to patients having invasive diseases, comorbid diseases, disability and death. The number of adults contracting Streptococcal pneumonia could be lowered dramatically with the use of proper vaccination, which is readily available. In 2022, the Center for Disease Control and the Advisory Committee on Immunization Practices (ACIP) release a new timing schedule and guidelines regarding the vaccination for pneumonia in the adult population. …

Moab Local Food Guide 2023, Roslynn Mccann, Shiree Duncan

All Current Publications

Thank you for picking up this Moab Utah Local Food Guide, last updated in May 2023. Those growing and producing food within a 100 mile radius from Moab have been included in this guide to help YOU make locally sourced purchasing decisions!

Catching Babies: Helping Students Understand Reproductive Justice Through Black Maternal Health, Jillian A. Tullis

Communication: Faculty Scholarship

No abstract provided.

Mass Spectrometry-Based Proteomic Analysis To Characterise Barley Breeding Lines, Mahya Bahmani

Theses: Doctorates and Masters

Barley is a key ingredient in the malting and brewing industry, and it is the fourth most important crop being cultivated worldwide. The protein content of the barley grain is one of the main components determining the quality and nutritive value of the food and beverages prepared from barley. Mass spectrometry-based proteomic analysis is a valuable tool that can guide and inform plant breeding strategies and crop improvement programs. Understanding the proteome changes in barley grain under different growing locations, the impact of different environmental conditions and its relationship with malting characteristics have the potential to inform breeding programs to …

Associations Between Oyster Consumption And Iron, Zinc, And Cadmium Concentrations In Ghanaian Women, Alyssa Abreu

Open Access Dissertations

Background: Oysters are an excellent source of iron and zinc but may be contaminated by heavy metals such as cadmium. The micronutrient and metal content of smoked, dried oysters as well as the impact of oyster consumption on iron, zinc, and cadmium concentrations in Ghana is unknown.

Objectives: Our objectives were to 1) determine the micronutrient and metal content and health risk of dried, smoked oysters, 2) determine the associations between dietary iron intake with hemoglobin or ferritin concentrations and anemia, 3) determine the associations between oyster consumption and iron, zinc and cadmium concentrations in Ghanaian women living near the …

Cranberry Vine And Its Effects On The Periparturient Ovine And Her Offspring, Delaney Smith

Open Access Dissertations

Gastrointestinal nematodes (GIN) are a major health concern globally, particularly for small ruminant producers. The most deadly of these GIN is an anemia-inducing parasite called Haemonchus contortus. Infections of H. contortus are most severe during what's known as the periparturient period (PPP), which is the last 6 weeks of gestation and first 8 weeks of lactation in maternal animals. Widespread genetic resistance of H. contortus to the traditionally used chemical dewormers have led producers and researchers alike to turn to the plant kingdom for answers. Plant based compounds have been used as bioactive compounds for centuries to cure a …

Elucidating The Mechanisms Of Stress Tolerance In Reef-Building Coral Holobionts, Emma Strand

Open Access Dissertations

Coral reefs worldwide are threatened by climate change effects like increasing ocean warming and ocean acidification. These increased pressures cause a dysbiosis between the coral host, algal endosymbionts, and associated coral microbiome that results in the coral host expelling algal endosymbionts, leaving the coral host with a stark white ‘bleached’ appearance. Without their endosymbionts, coral hosts are forced to sustain themselves energetically with heterotrophy instead of relying on the autotrophic carbon and energy sources that once came from the algal endosymbionts. When this response, termed ‘coral bleaching’, happens reef-wide during an extreme wave of increased ocean temperatures, this is called …

A Group Respite Intervention For Family Caregivers Of Children Living With Special Needs, Christine Mcgrane

Open Access Dissertations

Family caregiver stress is a growing healthcare concern as more and more families are providing a large portion of care at home. As a family caregiver, parents of children living with special needs are taking on this role as a lifelong journey with their child. Due to the provision of continuous caregiving, these parents are at higher risk for exhaustion, stress, and social isolation, and the challenges can impact both the child and family’s physical and emotional well-being. The demands of caregiving can impact their physical, mental, social, and financial health. As a society, the importance of caring for the …

Arts 3403 Printmaking Introduction, Acadia Kandora

All Syllabi

No abstract provided.

The Effect Of Acceptance And Commitment Therapy On Value Consistency During A Weight Loss Program, Leah Dorfman

Open Access Dissertations

In the last decade, the prevalence of obesity has increased significantly in populations worldwide. It is well established that overweight and obesity are associated with a host of deleterious health consequences. Standard Behavioral Therapy (SBT) for weight loss has been demonstrated to yield only modest outcomes with poor long-term maintenance. Therefore, efforts must be made to improve upon what is currently considered to be best practices in weight loss interventions, especially with a goal of improving retention and long-term maintenance. Acceptance and Commitment Therapy (ACT) is a behavioral and cognitive intervention that implements both acceptance and mindfulness processes, and commitment …