Digital Commons Network^™

Cardiac Output And Stroke Volume From The Pneumocardiogram: A New Mechanistic Insight And Practical Calculation, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Working Papers

This paper presents a new and more complete mechanism for the genesis of the pneumocardiogram—a record of the small oscillations in airflow in the trachea and upper airways accompanying each heartbeat. This signal may be the basis of a simple, inexpensive and noninvasive measure of cardiac stroke volume; however, research into its practical use has languished because of poor understanding of its underlying cause and meaning. This paper explains the genesis of the pneumocardiogram, based upon net changes in intrathoracic blood volume during the cardiac cycle, together with low pass filtering of the volume signal by airway resistance and lung-chest …

Majors And Minors, Saint Mary's College Of California

Undergraduate Academic Catalog

No abstract provided.

The Genetics Of Primary Ciliary Dyskinesia In Puerto Rico, Paolo Zanoni, Katharina Steindl, Heinrich Sticht, Beatrice Oneda, Pascal Joset, Ivan Ivanovski, Anselm H C Horn, Elena M Cabello, Julia Laube, Markus Zweier, Alessandra Baumer, Anita Rauch, Nadia Khan

Faculty, Staff and Student Publications

Pediatric Moyamoya Angiopathy (MMA) is a progressive intracranial occlusive arteriopathy that represents a leading cause of transient ischemic attacks and strokes in childhood. Despite this, up to now no large, exclusively pediatric MMA cohort has been subjected to systematic genetic investigation. In this study, we performed molecular karyotyping, exome sequencing and automated structural assessment of missense variants on a series of 88 pediatric MMA patients and correlated genetic, angiographic and clinical (stroke burden) findings. The two largest subgroups in our cohort consisted of RNF213 and neurofibromatosis type 1 (NF1) patients. While deleterious RNF213 variants were associated with a severe MMA …

By All Memes, I Want To Learn Arabic: Teachers’ And Students’ Perceptions Of Using Memes In Afl Classrooms, Amani Batran

Theses and Dissertations

Abstract

As educational technology advances, teachers nowadays tend to incorporate technology into their classroom practices to enhance students’ learning and achieve better outcomes. Memes, which are pictures with texts and sometimes movements circulated mostly among social media users, are a powerful tool to reach learning goals in a fun and engaging way. Researchers explored memes’ effectiveness in various disciplines, yet the field of teaching Arabic as a foreign language (AFL) lacks investigation in this area. Therefore, this study aims to examine teachers’ and students’ perspectives on the use of memes in the classroom. This research also explores the disparities in …

Nitric Oxide: Physiological Functions, Delivery, And Biomedical Applications, Syed Muntazir Andrabi, Navatha Shree Sharma, Anik Karan, S. M. Shatil Shahriar, Brent Cordon, Bing Ma, Jingwei Xie

Department of Mechanical and Materials Engineering: Faculty Publications

Nitric oxide (NO) is a gaseous molecule that has a central role in signaling pathways involved in numerous physiological processes (e.g., vasodilation, neurotransmission, inflammation, apoptosis, and tumor growth). Due to its gaseous form, NO has a short half-life, and its physiology role is concentration dependent, often restricting its function to a target site. Providing NO from an external source is beneficial in promoting cellular functions and treatment of different pathological conditions. Hence, the multifaceted role of NO in physiology and pathology has garnered massive interest in developing strategies to deliver exogenous NO for the treatment of various regenerative and biomedical …

The Effect Of Topical Oatmeal (Avena Sativa) On Hydration-Related Skin Disorders: A Systematic Review, Karenina Novani Sugondo, Melyawati Hermawan

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: In recent years, interest in developing cosmetics and beauty products based on natural ingredients has increased. The addition of herbal extracts to products could improve the effectiveness of therapy. One of the natural ingredients that can be found is oatmeal. Oatmeal has been used for a long time and has been approved by the U.S. Food and Drug Administration as a skin protective agent since 2003. This study aims to systematically review the literature to determine the effect of topical oatmeal (Avena sativa) on hydration-related skin disorders.

Methods: A total of 9,538 studies were found in the database sources …

Identifying Factors Contributing To Under-Five Mortality In Nigeria, Olateju Alao Bamigbala, Ayodeji Oluwatobi * Ojetunde

Tanzania Journal of Science

The under-5 mortality rate (U5MR) is the probability that a child born in a specified year will die before turning 5 years of age. U5MR is still high in Nigeria. Therefore, this study aimed to identify factors contributing to under-5 mortality in Nigeria. The data used in this study were from the 2018 NDHS, encompassing 2013–2018. The methods of analysis used for this study were frequency, percentage, and Zero Inflated Negative Binomial (ZINB) regression. Data were analyzed using R programming v.4.1.2 and p < 0.05 was considered to be statistically significant. The result showed 35.4% under-5 mortality out of the 33,924 infant mortality sample data that were collected. The findings revealed maternal age, regions (North East and North West), maternal education (no education), wealth index (poorest households), and size of child at birth (very small birth size) as significant factors associated with under-5 mortality in Nigeria. The results also showed that the odds of under-5 mortality increase as the age of the mother increases. Therefore, the Nigerian government should understand that poverty is not just an economic problem but also a significant factor in health; as a result, the battle against poverty needs to receive the necessary attention.  Keywords:    Under-5 mortality; World Health Organization; Zero inflated distribution; Risk factors; Nigeria.

Investigation Of Permanent Tattoos To Increase Myoelectric Signal Connectivity In Prosthetics, Guy Pugh

Master of Science in Kinesiology

Myoelectric prosthetics offer users increased functionality in many facits of their lives. However, maintaining reliable connectivity between sEMG sensors and targeted muscle locations can be problematic. Volume fluctuation of the residual limb, dirt, sweat, and movement of the socket and sensor over the limb can all because of signal disruption leading some users to find the myoelectric prostheses, costing thousands of dollars, to be unreliable, and stop using it. To increase connectivity between the optimal myoelectric sites and sEMG sensors, this paper proposes the use of permanent ink tattoos to create a stable location which a sensor can move over …

The Effects Of Hiit Versus Mict And Sedentary Controls On Blood Lipid Concentrations In Nondiabetic Overweight And Obese Young Adults: A Meta-Analysis., Christian P. Mccormick, Garrett Mamikunian, David B. Thorp

International Journal of Exercise Science

International Journal of Exercise Science 16(3): 791-813, 2023. With rates of obesity and dyslipidemia rising among young adults, this meta-analysis aimed to compare the effects of high-intensity interval training (HIIT) versus moderate-intensity continuous training (MICT) and sedentary controls (CON) on low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglyceride (TG), and total cholesterol (TC) in nondiabetic overweight and obese young adults to determine if HIIT or MICT is more efficacious in improving dyslipidemia. Studies included in the analysis had to be randomized controlled trials or quasi-experimental studies, comparing the effects of HIIT versus MICT or CON on at least three variables of …

Evaluation Of Two Methods To Estimate Wet Bulb Globe Temperature From Heat Index, Stephi Pofanl

USF Tampa Graduate Theses and Dissertations

The Wet bulb globe temperature (WBGT) is a common method to evaluate environmental factors that contribute to occupational heat stress. The Heat Index (HI) is readily available as an alternative to exposure methods. They both assess the most important contributors that are air temperature and humidity. WBGT also includes radiant heat and air motion. To account for radiant heat and/or air motion, some investigators have suggested adjustments to HI. The purpose of this study is to explore two methods to estimate the usefulness of WBGT from HI.

WBGT data were collected in a variety of locations that included direct sun …

Pentadesma Butyracea In Ghana – Indigenous Knowledge, Uses, And Seed Characterization, Josephine Akuba Timtey, Francis Alemawor, William Otoo Ellis, Nana Baah Pepra-Ameyaw, Jacob K. Agbenorhevi

Food Science Faculty Articles and Research

This study ascertained the indigenous knowledge and uses of Pentadesma butyracea plant through a focus group study. The proximate, mineral, antinutritional compositions, and antioxidant activity of P. butyracea seed were also determined using standard analytical methods. The results of the focus group study showed that P. butyracea is essentially used for its butter which is prepared by women processors who hand down the skill of butter processing to their children. The butter is used for cooking, frying, and preparing traditional delicacies, and the plant is known to possess some therapeutic potential. The seed recorded the following mean proximate values: fat …

2023 Central Washington University Commencement, Central Washington University

Commencement Programs

A commencement program from graduation ceremonies at Central Washington University.

Chronic, Mild Hypothermic Environmental Temperature Does Not Ameliorate Cognitive Deficits In An Alzheimer's Disease Mouse., Samuel Mcfadden, Lindsey N Sime, Makayla F Cox, Caleigh A Findley, Mackenzie R Peck, Kathleen Quinn, Yimin Fang, Andrzej Bartke, Erin R Hascup, Kevin N Hascup

Articles

Metabolic dysfunction increases with age and is a contributing factor to Alzheimer's disease (AD) development. We have previously observed impaired insulin sensitivity and glucose homeostasis in the APP/PS1 model of AD. To improve these parameters, we chronically exposed male and female mice to mild hypothermic environmental temperature (eT), which positively modulates metabolism. Although a hypothermic eT normalized insulin sensitivity, glucose tolerance was still impaired in both sexes of AD mice. We observed increased plasma glucagon and B-cell activating factor in both sexes, but additional sexually dimorphic mechanisms may explain the impaired glucose homeostasis in AD mice. Hepatic Glut2 was decreased …

Localized Pain And Fatigue During Recovery From Submaximal Resistance Exercise In People With Fibromyalgia, Giovanni Berardi, Christine Eble, Sandra K. Hunter, Marie K. Hoeger Bement

Exercise Science Faculty Research and Publications

Objective

Exercise is recommended as a main treatment in fibromyalgia. However, many people have limited exercise tolerance and report exacerbated pain and fatigue during and following a bout of exercise. This study examined the local and systemic changes in perceived pain and fatigue during exercise and through the 3-day recovery following isometric and concentric exercises in people with and without fibromyalgia.

Methods

Forty-seven participants with a physician diagnosis of fibromyalgia (44 women; mean age [SD] = 51.3 [12.3] years; mean body mass index [SD] = 30.2 [6.9]) and 47 controls (44 women; mean age [SD] = 52.5 [14.7] years; mean …

Influence Of Age And Gender On Alveolar Bone Healing Post Tooth Extraction In 129 Sv Mice: A Microtomographic, Histological, And Biochemical Characterization, Cláudia Cristina Biguetti, Bhuvana Lakkasetter Chandrashekar, Gustavo Baroni Simionato, Nataira Regina Momesso, Marco Antonio Hungaro Duarte, Danieli C. Rodrigues, Mariza Akemi Matsumoto

School of Podiatric Medicine Publications

Objectives

To analyze the effect of biological sex and aging on craniofacial bone features in 129 Sv mice and their influence on dental socket healing post tooth extraction.

Materials and methods

A total of 52 129 Sv mice were used, of which 28 were young (3–4 months) and 24 were aged (17–18 months), equally distributed according to biological sex. After an upper right incisor extraction, mice specimens were collected at 7, 14, and 21-days post-surgery for microtomographic (microCT) and comprehensive histological analysis. Mandible, skull bones, and maxillae at 21 days were analyzed by microCT, while blood plasma samples were collected …

Impact Of Transfused Citrate On Pathophysiology In Massive Transfusion, Jacob B Schriner, J Michael Van Gent, M Adam Meledeo, Scott D Olson, Bryan A Cotton, Charles S Cox, Brijesh S Gill

Faculty, Staff and Student Publications

This narrative review article seeks to highlight the effects of citrate on physiology during massive transfusion of the bleeding patient.

DATA SOURCES: A limited library of curated articles was created using search terms including "citrate intoxication," "citrate massive transfusion," "citrate pharmacokinetics," "hypocalcemia of trauma," "citrate phosphate dextrose," and "hypocalcemia in massive transfusion." Review articles, as well as prospective and retrospective studies were selected based on their relevance for inclusion in this review.

STUDY SELECTION: Given the limited number of relevant studies, studies were reviewed and included if they were written in English. This is not a systematic review nor a …

Circadian Features Of Cluster Headache And Migraine: A Systematic Review, Meta-Analysis, And Genetic Analysis, Barlas Benkli, Sun Young Kim, Nobuya Koike, Chorong Han, Celia K Tran, Emma Silva, Yuanqing Yan, Kazuhiro Yagita, Zheng Chen, Seung-Hee Yoo, Mark J Burish

Faculty, Staff and Student Publications

BACKGROUND AND OBJECTIVES: Cluster headache and migraine have circadian features at multiple levels (cellular, systems, and behavioral). A thorough understanding of their circadian features informs their pathophysiologies.

METHODS: A librarian created search criteria in MEDLINE Ovid, Embase, PsycINFO, Web of Science, and Cochrane Library. Two physicians independently performed the remainder of the systematic review/meta-analysis using Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines. Separate from the systematic review/meta-analysis, we performed a genetic analysis for genes with a circadian pattern of expression (clock-controlled genes or CCGs) by cross-referencing genome-wide association studies (GWASs) of headache, a nonhuman primate study of CCGs …

Lateral Septum As A Melanocortin Downstream Site In Obesity Development, Yuanzhong Xu, Zhiying Jiang, Hongli Li, Jing Cai, Yanyan Jiang, Joshua Otiz-Guzman, Yong Xu, Benjamin R Arenkiel, Qingchun Tong

Faculty, Staff and Students Publications

The melanocortin pathway is well established to be critical for body-weight regulation in both rodents and humans. Despite extensive studies focusing on this pathway, the downstream brain sites that mediate its action are not clear. Here, we found that, among the known paraventricular hypothalamic (PVH) neuron groups, those expressing melanocortin receptors 4 (PVHMc4R) preferably project to the ventral part of the lateral septum (LSv), a brain region known to be involved in emotional behaviors. Photostimulation of PVHMc4R neuron terminals in the LSv reduces feeding and causes aversion, whereas deletion of Mc4Rs or disruption of glutamate release from LSv-projecting PVH neurons …

Toxicological Evaluation Of A Polyherbal Formulation On Testicular Function And Gonadal Histomorphology In Exposed Wistar Rats, Godswill James Udom, Uduak Peter Ise, Omoirri Moses Aziakpono, Ayodeji Aturamu, Mba Ogbonnaya, Israel Kevin Umana, Jude Efiom Okokon

BioMedicine

Introduction: Dr Iguedo Goko Cleanser® is a herbal formulation (HF) widely marketed in southern Nigeria and purported to be very efficacious for the management of various diseases including giardiasis, toilet infections, hypertension, diabetes, ulcer, impotence, low libido, low sperm count amongst others. Medicinal plants reportedly produce an array of adverse reactions capable of inducing harmful conditions, including death. Aim: This study evaluated the subchronic toxicity concern of HF on testicular function and gonadal histoarchitecture in Wistar rats. Methods: Thirty Wistar rats of both sexes were randomly divided into six groups (5/group) and were orally administered HF for 60 days. The …

Association Of Smoking And Respiratory Disease History With Pancreatic Pathologies Requiring Surgical Resection, Carolyn Ream, Matthew Sabitsky, Rachel Huang, Emma Hammelef, Theresa P. Yeo, Harish Lavu, Charles J. Yeo, Wilbur Bowne, Avinoam Nevler

Student Papers, Posters & Projects

Background: The purpose of this study was to examine the relationship between various respiratory conditions, including hypercapnic respiratory disease, and a multitude of resected pancreatic lesions. Methods: This retrospective case-control study queried a prospectively maintained database of patients who underwent pancreaticoduodenectomy between January 2015 and October 2021. Patient data, including smoking history, medical history, and pathology reports, were recorded. Patients with no smoking history and no concomitant respiratory conditions were designated as the control group. Results: A total of 723 patients with complete clinical and pathological data were identified. Male current smokers showed increased rates of PDAC (OR 2.33, 95% …

Utilizing New Technologies To Measure Therapy Effectiveness For Mental And Physical Health, Jonathan Ossie

Dissertations

Mental health is quickly becoming a major policy concern, with recent data reporting increasing and disproportionately worse mental health outcomes, including anxiety, depression, increased substance abuse, and elevated suicidal ideation. One specific population that is especially high risk for these issues is the military community because military conflict, deployment stressors, and combat exposure contribute to the risk of mental health problems.

Although several pharmacological approaches have been employed to combat this epidemic, their efficacy is mixed at best, which has led to novel nonpharmacological approaches. One such approach is Operation Surf, a nonprofit that provides nature-based programs advocating the restorative …

Ecological Validity Of Immersive Virtual Environment Experiments On Human Thermal State And Behavioral Intentions: Experimental Protocol Factors, Girish Rentala

LSU Doctoral Dissertations

Using immersive virtual environment (IVE) based experiments to investigate human thermal states and thermal adaptive behaviors during the building design phase could help identify potential comfort issues and enable designers to optimize building performance cost-effectively before the actual building construction. However, to effectively utilize IVEs to study thermal states/adaptive behaviors, it is crucial to ensure the ecological validity of IVE experiment protocols. This entails accurately representing in-situ (real) environments within IVEs and establishing comparability and generalizability of data collected under different thermal stimuli between IVE and in-situ environments. Existing thermal stimuli based IVE studies have not effectively evaluated the ecological …

Commencement 2023, Taylor University

Commencement

The program of the 2023 Annual Commencement of Taylor University, May 20, 2023.

A Nonlinear Impact-Driven Triboelectric Vibration Energy Harvester For Frequency Up-Conversion, Hadeel Abumarar, Alwathiqbellah Ibrahim

Mechanical Engineering Faculty Publications and Presentations

Energy harvesting effectively powers micro-sensors and wireless applications. However, higher frequency oscillations do not overlap with ambient vibrations, and low power can be harvested. This paper utilizes vibro-impact triboelectric energy harvesting for frequency up-conversion. Two magnetically coupled cantilever beams with low and high natural frequencies are used. The two beams have identical tip magnets at the same polarity. A triboelectric energy harvester is integrated with the high-frequency beam to generate an electrical signal via contact-separation impact motion between the triboelectric layers. An electrical signal is generated at the low-frequency beam range achieving frequency up-converter. The two degrees of freedom (2DOF) …

The Development Of A Dance/Movement Therapy Method For Social Engagement With Adolescents In A Partial Hospital Program, Kayleah Pensalfini

Expressive Therapies Capstone Theses

Mental health can significantly impede navigating the social domain during adolescence. Research has indicated social development of adolescents may be impacted by psychopathology and emotional development, further hindering one’s formation of self. There is also limited research showing the effectiveness of Dance/Movement Therapy (DMT) with the adolescent population. This writer designed and adapted one DMT session for adolescents to understand this topic better. This capstone will present an adaptable method utilizing a DMT intervention with participants between the ages of 13-17 in a Partial Hospital Program (PHP). This project aimed to examine how DMT can support self-identity and the acquisition …

Dance/ Movement Therapy As A Primary Therapeutic Intervention To Improve Social And Communication Skills Of Children With Autism Spectrum Disorder: A Literature Review, Allyssa Millar

Expressive Therapies Capstone Theses

This literature review examines dance movement therapy as an intervention to help children with autism spectrum disorder strengthen social and communication skills. Social barriers due to autism include taking turns, making decisions, participating in joint attention, recognizing emotions in others, and recognizing social cues. Communication skills in children with autism can vary from being unable to verbally express wants and needs to only utilizing gestures to communicate. Dance movement therapy uses the strengths of the children to help develop a communication system that can be understood by those around them. Research studies help to show that use of dance movement …

Massive Misunderstood Menace: Gojira (1954), An Allegory For Coping With Trauma, Marc-Antony Martinez

Master's Projects and Capstones

Abstract

In my essay I will be examining whether exposure therapy is an effective method of those coping with PTSD. This is an idea which circulates around the original 1954 Gojira film, where its ending can be interpreted as supporting the idea that coping with trauma must necessarily involve some form of exposure therapy. In the end my research concludes that exposure therapy is effective for those suffering with PTSD under a select few circumstances. This is because trauma can spur symptoms, including borderline personality syndrome, that can negatively affect the outcome of exposure therapy. Despite this, exposure therapy is …

Innovator - Spring 2023

Innovator

03 - The President’s Column

06 - Time Machine: Fabric of the Heart

10 - The Nexus: News at Jefferson

20 - Student to #Philebrity: Influenced by Jefferson

24 - The Light Fantastic

30 - We Are One Jefferson

34 - Question & Innovate

36 - Reimagine

40 - Ram Roundup

44 - Class Notes

56 - In Memory

58 - Trivia

The Echo: May 15, 2023, Taylor University

2022-2023 (Volume 110)

No abstract provided.

Human Diversity In Molecular Sexual Dimorphism And Gender Disparities In Health, Adam Z. Reynolds

Anthropology ETDs

Although males and females exhibit an extraordinary range of diversity in sexual dimorphism across populations, prior work on the evolution of sexual dimorphism in human physiology and health has focused on ostensibly universal differences that owe to sex chromosomes and steroid hormones. This dissertation argues that sexual dimorphism in humans is not adequately captured by species-wide sex differences in mean trait values, but instead varies greatly as a result of: (i) our ability to adapt physiologically to a broad range of social and physical environments, and (ii) molecular diversity acquired by different populations over the course of their unique evolutionary …