Digital Commons Network^™

Looking Into The “Dark Mirror”: Autoethnographic Reflections On The Impact Of Covid-19 And Change Fatigue On The Wellbeing Of Enabling Practitioners, Angela Jones, Susan Hopkins, Ana Larsen, Joanne Lisciandro, Anita Olds, Marguerite Westacott, Rebekah Sturniolo-Baker, Juliette Subramaniam

Research outputs 2022 to 2026

The COVID-19 pandemic brought global disruptions to the way universities operate. Online learning abruptly took priority, as the physical campuses in Australian universities became deserted. Staff had to instantly adapt to major changes in work practices, whilst continuing to support students’ engagement and maintain quality teaching and learning. This article discusses how change fatigue during the pandemic impacted the wellbeing of staff working in the enabling education sector. As staff and student wellbeing is interdependent, gaining a better understanding of the influences on staff wellbeing in the post-pandemic era is worth exploring in the context of discussions around student wellbeing …

Antibody Binding Captures High Energy State Of An Antigen: The Case Of Nsp1 Sars-Cov-2 As Revealed By Hydrogen-Deuterium Exchange Mass Spectrometry, Ravi Kant, Nawneet Mishra, Michael L Gross

2020-Current year OA Pubs

We describe an investigation using structural mass spectrometry (MS) of the impact of two antibodies, 15497 and 15498, binding the highly flexible SARS-CoV-2 Nsp1 protein. We determined the epitopes and paratopes involved in the antibody-protein interactions by using hydrogen-deuterium exchange MS (HDX-MS). Notably, the Fab (Fragment antigen binding) for antibody 15498 captured a high energy form of the antigen exhibiting significant conformational changes that added flexibility over most of the Nsp1 protein. The Fab for antibody 15497, however, showed usual antigen binding behavior, revealing local changes presumably including the binding site. These findings illustrate an unusual antibody effect on an …

Reproductive Decision Making In Women With Medical Comorbidities: A Qualitative Study, Elena M Kraus, Niraj R Chavan, Victoria Whelan, Jennifer Goldkamp, James M Dubois

2020-Current year OA Pubs

BACKGROUND: A growing number of reproductive-age women in the U.S. have chronic medical conditions, increasing their risk of perinatal morbidity and mortality. Still, they experience unintended pregnancies at similar rates to low-risk mothers. We have limited understanding of how these individuals consider decisions about pregnancy and contraceptive use. The purpose of this study was to understand factors that influence reproductive decision-making among pregnant women with chronic medical conditions.

METHODS: We conducted 28 semi-structured interviews with pregnant women with pre-existing medical conditions admitted to a tertiary maternal hospital to examine factors influencing reproductive decision making. Maternal demographic characteristics, medical history, and …

Interventions To Promote Cost-Effectiveness In Adult Intensive Care Units: Consensus Statement And Considerations For Best Practice From A Multidisciplinary And Multinational Edelphi Study, Amit Kansal, Jos M. Latour, Kay Choong See, Sumeet Rai, Maurizo Cecconi, Carl Britto, Morris A Conway, Rd Savio, Vinay M. Nadkarni, B. K. Rao, Rajesh Mishra

School of Nursing and Midwifery

Background There is limited evidence to guide interventions that promote cost-effectiveness in adult intensive care units (ICU). The aim of this consensus statement is to identify globally applicable interventions for best ICU practice and provide guidance for judicious use of resources. Methods A three-round modified online Delphi process, using a web-based platform, sought consensus from 61 multidisciplinary ICU experts (physicians, nurses, allied health, administrators) from 21 countries. Round 1 was qualitative to ascertain opinions on cost-effectiveness criteria based on four key domains of high-value healthcare (foundational elements; infrastructure fundamentals; care delivery priorities; reliability and feedback). Round 2 was qualitative and …

Employment, Income, And Poverty In Kalamazoo City Core Neighborhoods, Val Klomparens

Reports

This report employs a traditional methodology using American Community Survey data to examine employment, income, and poverty in three neighborhoods in Kalamazoo, Michigan: Eastside, Northside, and Edison. These neighborhoods are studied with an emphasis on eligibility status for the Distressed Area Recompete Pilot Program, administered through the U.S. Economic Development Administration. Eastside residents are unique in that a larger share earn income through wages or employment than do Michigan residents, yet their median income falls below those at the county and state levels in a statistically significant way. The Edison neighborhood is characterized by greater income inequality than the other …

Review Of "The #Actuallyautistic Guide To Advocacy: Step-By- Step Advice On How To Ally And Speak Up With Autistic People And The Autism Community", Jennifer M. Brady

The Christian Librarian

No abstract provided.

An Educational Intervention To Increase Knowledge And Awareness Of Hypertension Among Nurses, Sylvia Kabba

Walden Dissertations and Doctoral Studies

No abstract provided.

Response Differences Of Two Maize Hybrid Varieties To The Application Of Bioagent-Ameliorant And Chicken Manure In Fertile Soil, Endang Kantikowati, Karya, Yudi Yusdian, Dian Murti Minangsih, Tien Turmuktini, Erna Yuliani, Fija Faujiah

Jurnal Kultivasi

To ensure adequate nutrition for the growth of maize (Zea mays L.) in sustainable agriculture, it is necessary to apply bio-agent soil conditioner and manure. This study aims to determine the effect of doses of bioagent-ameliorant and chicken manure on growth and yield components. The research was conducted in highland with an altitude 800 m above sea level. This study used an experimental method with two sets of experiments, namely experiments using one and two-cobs maize cultivars. The experiment used a randomized block design (RBD) with two treatment factors and three replications. The first treatment factor was the dose of …

Morphophysiological Characteristics Of Upland Rice Plants With Organic Approach Through Reduced Npk Fertilizer And Wood Vinegar Application, Yugi Rahayu Ahadiyat, Ahmad Fauzi

Jurnal Kultivasi

Unefficient use of synthetic fertilizer in upland rice production leads to the low productivity and tends to harm the environtment. An organic approach by using wood vinegar is promising to improve the fertilizer efficiency. The objective of this study was to determine the response of upland rice with the application of different wood vinegar and synthetic fertilizer N-P-K rates on morpho-physiological characters. A split plot design with the main plot of N-P-K fertilizer and a subplot of wood vinegar was applied with three replications. Growth and physiological character were observed. The data were analyzed by the F test, then proceed …

Bringing Car T Cell Therapy Trials To Underserved Populations, Hoda Badr, Rayne Rouce, Michael E Scheurer, Premal Lulla, Martha Mims, Pavan Reddy

Faculty, Staff and Students Publications

There is a critical need for equitable access to cell therapies in cancer treatment, particularly within public safety-net healthcare systems that serve minority and socioeconomically disadvantaged populations. We discuss how the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine is piloting a cell therapy program aimed at addressing cancer care disparities and has the potential to serve as a national model for enhancing health equity in cancer care.

Allelic Strengths Of Encephalopathy-Associated Uba5 Variants Correlate Between In Vivo And In Vitro Assays, Xueyang Pan, Albert N Alvarez, Mengqi Ma, Shenzhao Lu, Michael W Crawford, Lauren C Briere, Oguz Kanca, Shinya Yamamoto, David A Sweetser, Jenny L Wilson, Ruth J Napier, Jonathan N Pruneda, Hugo J Bellen

Faculty, Staff and Students Publications

Protein UFMylation downstream of the E1 enzyme UBA5 plays essential roles in development and endoplasmic reticulum stress. Variants in the UBA5 gene are associated with developmental and epileptic encephalopathy 44 (DEE44), an autosomal recessive disorder characterized by early-onset encephalopathy, movement abnormalities, global developmental delay, intellectual disability, and seizures. DEE44 is caused by at least 12 different missense variants described as loss of function (LoF), but the relationships between genotypes and molecular or clinical phenotypes remain to be established. We developed a humanized UBA5 fly model and biochemical activity assays in order to describe in vivo and in vitro genotype–phenotype relationships …

Managing Soil Ph For Crop Production In Calcareous-Alkaline Soil, Cody Zesiger, Jody Gale, Matt Yost, Grant Cardon

All Current Publications

In semiarid soils of the Western U.S., altering soil pH is not easily accomplished nor straightforward. Utah’s soil pH range can be 1,000 times more acidic or alkaline than neutral (7.0) pH soils. In semiarid regions, typical high-pH soils are also calcareous, meaning there is a large amount of solid calcium carbonate (lime) in the soil. When soil-acidifying amendments are added to these soils, the lime dissolves and counteracts any of the applied soil-acidifying amendments. This fact sheet explains how to identify whether crop symptoms are related to soil pH, how to perform an in-field test for soil pH buffering …

Applications Of Implementation Science Frameworks, Models And Theories In Disparities-Focused Cancer Screening Interventions: A Scoping Review Protocol, Serena Xiong, Lisa Klesges, Michelle Doering, Rebekah J Pratt

2020-Current year OA Pubs

BACKGROUND: Implementation science (IS) frameworks, models and theories (FMTs) have gained popularity in guiding the implementation and evaluation of evidence-based interventions (EBIs) for cancer screening. However, there are significant research gaps in understanding their applications in cancer health disparities contexts. This paper outlines a scoping review protocol designed to explore the utilisation of IS FMTs in cancer screening EBIs to inform intervention designs and adaptations.

METHODS AND ANALYSIS: This scoping review protocol adheres to Arksey and O'Malley's five-step methodological framework for conducting scoping studies. Search strategies were conducted in five bibliographic databases: Ovid MEDLINE, PubMed, Scopus, Web of Science and …

Employment Leave For Early Pregnancy Endings: A Biopolitical Reproductive Governance Analysis In England And Wales, Al Middlemiss, I Boncori, J Brewis, J Davies, Vl Newton

School of Nursing and Midwifery

When a pregnancy ends in England and Wales, statutory time away from paid employment is limited to circumstances where there is a live birth or stillbirth. Forms of leave, such as Maternity Leave or Paternity Leave, depend on parental status derived from the civil registration of a new person or a post-viability stillbirth. Other early pregnancy endings, such as miscarriage or abortion, do not provide specific time off work after pregnancy. This paper uses the concept of reproductive governance to analyze current and shifting biopolitical truth discourses, strategies of intervention, and modes of subjectification around post-pregnancy leaves. It shows how …

Audit And Feedback To Reduce Unwarranted Clinical Variation At Scale: A Realist Study Of Implementation Strategy Mechanisms, Mitchell Sarkies, Emilie Francis-Auton, Janet Long, Natalie Roberts, Johanna Westbrook, Jean Frederic Levesque, Diane E. Watson, Rebecca Hardwick, Kim Sutherland, Gary Disher, Peter Hibbert, Jeffrey Braithwaite

Peninsula Medical School

Background Unwarranted clinical variation in hospital care includes the underuse, overuse, or misuse of services. Audit and feedback is a common strategy to reduce unwarranted variation, but its effectiveness varies widely across contexts. We aimed to identify implementation strategies, mechanisms, and contextual circumstances contributing to the impact of audit and feedback on unwarranted clinical variation. Methods Realist study examining a state-wide value-based healthcare program implemented between 2017 and 2021 in New South Wales, Australia. Three initiatives within the program included audit and feedback to reduce unwarranted variation in inpatient care for different conditions. Multiple data sources were used to formulate …

Engineering Exosomes To Specifically Target The Mitochondria Of Brain Cells, Xin Yan, Xinqian Chen, Zhiying Shan, Lanrong Bi

Michigan Tech Publications

Mitochondrial dysfunction is associated with various health conditions, including cardiovascular and neurodegenerative diseases. Mitochondrial-targeting therapy aims to restore or enhance mitochondrial function to treat or alleviate these conditions. Exosomes, small vesicles that cells secrete, containing a variety of biomolecules, are critical in cell-to-cell communication and have been studied as potential therapeutic agents. Exosome-based therapy has the potential to treat both cardiovascular and neurodegenerative diseases. Combining these two approaches involves using exosomes as carriers to transport mitochondrial-targeting agents to dysfunctional or damaged mitochondria within target cells. This article presents a new technique for engineering brain-derived exosomes that target mitochondria and has …

Advanced Diffusion Mri Technique And Applications In Placenta And Brain, Zhexian Sun

McKelvey School of Engineering Graduate Student Theses & Dissertations

Among a series of contrasts of MRI, diffusion MRI (dMRI) is different from conventional MRI by its ability to capture information about the random movement of water molecules and their interaction with local tissue microstructures. This capability holds the potential to reveal intricate subvoxel microstructural information linked to pathological changes, offering potential imaging biomarkers. A higher-order diffusion analysis model helps to yield more accurate and specific parameters but requires more extensive parameter tuning and higher image quality. In this study, we firstly fine-tuned the previously developed diffusion basis spectrum imaging (DBSI) method to strike a balance between efficiency and accuracy …

You Bury Me, William O'Reilly

Valparaiso Fiction Review

No abstract provided.

Which Internet Content Is Often Used And Influenced Behavior? A Phenomenology About Students In Senior High School, Aris Martina, Siti Irene Astuti Dwiningrum, Heri Retnawati, Caly Setiawan

Informasi

At present, most students in the world, as well as Indonesia, especially senior high school students, have used the Internet for various purposes. Internet content presented on different platforms can now be accessed easily. Consciously or not, this media content influences their behavior. There is a lot of freely submitted content, which is worth knowing the impact. The question related to this study is which internet content is often used and affects high school students’ behavior. Qualitative methods with phenomenology have informants from the western, central, and eastern parts of Indonesia. Data were collected using observation, Google Forms, and interviews …

Shading The Future: A Gis-Based Approach To Optimal Tree Planting For Urban Heat Mitigation At Northern Michigan University, Mary Kelly

Conspectus Borealis

Increasing tree canopy cover is a powerful tool for mitigating the effects of urban heat on the natural and built environment, specifically the effects of ecosystem stress and air quality. Heat can also place stress on human health. Northern Michigan University (NMU) is proposing to build a new tree nursery on campus, which would help alleviate urban heat in Marquette. Finding suitable areas at NMU to plant new trees from this nursery is an essential component of this effort. A goal of my project was to provide this helpful information. Using GIS and remote sensing techniques in ArcGIS Pro and …

What The World Has Learned About Their Governments During The Covid-19 Pandemic, Olga Shvetsova

Political Science Faculty Scholarship

As we take stock of all aspects of the COVID-19 pandemic history, one important lesson to be learned concerns government behavior. While defense by immunity was in the works in vaccine research labs, defense by government action took the front seat, and political incumbents in every country and locale became "doctors to the public.” Did some governments perform better than others? Were there any predictable or explainable shortcomings in their crisis responses? Will governments and countries that underperformed in this crisis fall short in other crises where responsible leadership might be required? The contributors to this volume compare and contrast …

Commonalities And Differences In Governments’ Covid-19 Public Health Responses Around The World, Olga Shvetsova, Andrei Zhirnov

Political Science Faculty Scholarship

As the world enters the era of increased frequency of global health crises and natural disasters, with climate change looming as an ever-present threat, how we govern ourselves matters for the ways in which we will live through these difficult times. The authors in this volume provide observations backed by mixed methods of analysis on the many ways in which government organization and political realities affect crisis response and crisis management. In this chapter, we further strengthen the validity of their findings with large N global sample analyses where the timing and stringency of the adoption of public health policies …

The Benefits Of Drama Therapy With Children And Adolescents, Rebecca Gallant

Honors Program Theses and Projects

Drama therapy, as defined by the North American Drama Therapy Association is “the intentional use of drama and/or theater processes to achieve therapeutic goals…an embodied practice that is active and experiential. This approach can provide the context for participants to tell their stories, set goals and solve problems, express feelings, or achieve catharsis” (NADTA 2021). NADTA was established in 1979 as an organization to advocate for drama therapy and to ensure that drama therapists are upholding the proper qualifications to practice. As noted by the organization, drama therapy can be used in a variety of different settings, including classrooms, nursing …

Gender Differences In Youth’S Mental Health Problems During The Covid-19 Pandemic, Kimberly A. Hohlfeld

Honors Capstones

The purpose of this research paper is to examine whether young girls were more likely to experience depression and anxiety symptoms than young boys during the COVID-19 pandemic at two time points, in April of 2020 and May of 2020. An additional hypothesis that was examined was whether the presence of siblings in the home moderated the association between gender and depression and anxiety symptoms during the COVID-19 pandemic. T-tests were used to analyze the mean differences in youth mental health symptoms based on gender. Young girls were found to experience significantly higher anxiety symptoms in May of 2020 than …

Breaking Down Barriers To Aid: A 16 Days Of Activism Q&A With Chi-Chi Undie, Population Council

Sexual and Reproductive Health, Rights, and Choices

No abstract provided.

Employing Telepsychiatry Services To Assess The Prevalence And Identify Mental Health Disorders Using The Phq-9 And Gad-7 In Resource-Constrained Regions Of Dadar Mansehra, Pakistan: An Observational Cross-Sectional Study, Iffat Zafar Aga, Sara Saeed Khurram, Mahek Karim, Muhammad Muzzamil, Shahkamal Hashmi, Kashif Shafique

Medical College Documents

Objective: This study aims to measure the prevalence of mental health disorders in low-resource settings through telepsychiatry and evaluate data from Pakistan's Sehat Kahani nurse-assisted online clinics serving low-income communities. This will help to understand the magnitude and nature of the demand for contextual therapies to promote mental health. The paper will discuss the challenges faced in these settings, such as limited access to mental health facilities, stigma and opportunities telemedicine brings.
Design: An observational cross-sectional study of telepsychiatry consultations using Patient Health Questionnaire-9 and Generalised Anxiety Disorder-7 to screen for depression and anxiety was conducted between October and December …

Episode 6: For The Kids, Sara Gras

Season 01

When I started thinking about how to address the issue of trans exclusion from youth sports, I knew I needed to include the culture/industry of youth sports as part of the discussion. The pressure to compete and perform at a high level in athletics is reaching kids earlier than ever before, facilitated by parents who see success in sports as the ticket to success in life. This episode explores the relationship between the increased parental investment in kids' athletic achievements and the social acquiescence to the exclusion of trans kids from sports.

Kirsten Jones
Peak Performance Coach, Podcast Host, Author …

Impact Of Syntax Scores On The Long-Term Outcomes Of Coronary Artery Bypass Grafting And Percutaneous Coronary Intervention For Left Main Coronary Artery Disease, Faiq Murteza, Chabib Fachry Albab, Almas Talida Habibah, Achmad Fayyad Mas'udi, Vemaniarti Lian Pravitasari, Arya Satya Rajanagara, Zaha El-Ma'i

Folia Medica Indonesiana

The Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score was designed to predict the post-procedural risk associated with percutaneous coronary intervention (PCI) or surgical revascularization. This study aimed to evaluate the long-term outcomes of PCI and coronary artery bypass grafting (CABG) by comparing several existing studies. A systematic search was performed using the PubMed (MEDLINE) and ScienceDirect databases. This systematic review included studies that examined differences in the outcomes of PCI and CABG for left main coronary artery (LMCA) stenosis. This was a systematic review study in which we reviewed original cross-sectional and cohort studies. The …

Mirror Therapy Rehabilitation In Low Back Pain Patients, Claudia L. Altergott

Honors Capstones

Low back pain is a common occurrence experienced by many individuals. An estimated 75-85% of Americans experience some form of back pain during their lives [1]. While low back pain can be uncomfortable and debilitating, approximately 90% of cases are temporary and can resolved without surgery; however, 50% of patients will experience recurrent episodes of back pain. Low back pain that has persisted for more than twelve weeks is considered chronic low back pain [1]. Many researchers and therapists have been seeking the optimal treatment plans for individuals suffering from low back pain. Mirror therapy (MT) is a type of …

Ablation Of Accessory Pathway From Right Atrial Appendage To Anatomic Left Ventricle In L-Transposition Of The Great Arteries, Shree Lata Radhakrishnan, Robert O. Drutel, Cody M. Williams, Raman Danrad, Kelly K. Gajewski, Paul A. Lelorier

School of Medicine Faculty Publications

No abstract provided.