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A Mathematical Model For Frogeye Leaf Spot Epidemics In Soybean, Chayu Yang, Jin Wang

Department of Mathematics: Faculty Publications

We propose a new mathematical model based on differential equations to investigate the transmission and spread of frogeye leaf spot, a major soybean disease caused by the fungus Cercospora sojina. The model incorporates the primary and secondary transmission routes of the disease as well as the intrinsic dynamics of the pathogen in the contaminated soil. We conduct detailed equilibrium and stability analyses for this model using theories of dynamical systems. We additionally conduct numerical simulations to verify the analytical predictions and to implement the model for a practical application.

The First Report Of Using Low-Field Mri-Guided Radiation Therapy In A Patient With A Cochlear Implant, James Mcculloch, Nema Bassiri Gharb, Alonso Gutierrez, Jennifer Armas, Kevin Abrams, Minesh Mehta, Michael Chuong, Kathryn Mittauer

All Publications

No abstract provided.

Berberine - A Natural Supplement Review, Emily Tackett, Hannah Blake, Kaitlyn Kirby, Abigail Carter, Brianna Lu, Joshua Honaker, Kelly Shields

Pharmacy and Wellness Review

Berberine (BBR) is a chemical found in plants that has been used in medicine for generations across many cultures. Early uses of BBR included maladies such as colds, infections, and jaundice. As technology and understanding have progressed, BBR has been developed into oral formulations to promote better absorption and is being evaluated for use in various disease states. Due to its actions as a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, BBR is being evaluated for its potential use in the management of hyperlipidemia and cardiovascular disease. Multiple studies support claims of BBR’s lipid-lowering effects, with stronger evidence when given …

Hippotherapy Within Physical Therapy Treatment: Helping Patients With Cerebral Palsy Achieve Functional Goals, Grace Kucienski

Honors Capstones

Hippotherapy is a treatment tool that can be utilized by trained occupational therapists, speech language pathologists, and physical therapists. It involves the utilization of a horse’s movement to facilitate certain sensory, adaptive, neuromotor, cognitive, and physical responses from a patient. The purpose of this project is to examine how hippotherapy as a treatment tool in physical therapy benefits children with cerebral palsy. The examination of this subject matter was conducted in a case study format. For twelve weeks, one patient with cerebral palsy’s physical therapy sessions utilizing hippotherapy were observed. During these sessions, her progress towards reaching a specific functional …

Hypertension And Lipid Profiles In Middle-Aged Male Patients: A Study At A Tertiary Hospital In Surabaya, Indonesia, Arin Nurtya, Artaria Tjempakasari, Ummi Maimunah, Sulistiawati, I Made Subhawa Harsa

Folia Medica Indonesiana

Highlights: 1. Uncertainty regarding the association between hypertension and the levels of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) signifies the need for more research, particularly in the realm of sex-specific analysis. 2. Our study uncovered significant associations between hypertension and the levels of total cholesterol and triglycerides, expanding our understanding of the impact of lipid profiles on hypertension. 3. This research may potentially pave the way for personalized diagnostic and therapeutic strategies, ultimately enhancing hypertension management and patient outcomes. Abstract Hypertension is one of the most frequent non-communicable diseases and a risk factor for cardiovascular disease, contributing to most …

Effect Of Short-Term Extra Maltodextrin During A Diet Break On The Resistance Training Performance Of Rattus Norvegicus, Muhammad Irfan Indiarto, Irfiansyah Irwadi, Lina Lukitasari, Atika

Folia Medica Indonesiana

Highlights: 1. The ongoing advancement of dietary research has significant importance in the exploration of strategies to optimize the impact of nutrition on performance during resistance training. 2. This study provides a prompt for future research to explore the effectiveness of incorporating an additional dietary strategy that may enhance resistance training performance. Abstract: Poor diet with a purpose to lose a certain body weight or body fat can impair muscle protein synthesis. This results in muscle loss and poor performance in physical training, particularly resistance training. This study aimed to determine the short-term effect of extra carbohydrates, specifically in the …

2023-December-10-Illuminating The Path I Want To Take, University Marketing And Communication, East Tennessee State University

ETSU News

Internships are the strength of ETSU’s Applied Data Science grad program

It’s an age-old conundrum. Employers want to hire candidates with experience. But how do you get that experience without someone giving you a chance?

One way is internships, many of which are available to students in academic programs throughout East Tennessee State University. One of those is ETSU’s Applied Data Science Master’s Degree Program, where students are getting valuable experience from the hands-on work they’re doing with entities from local small businesses and government to internationally known companies.

Applied data science is the study of techniques for collecting, …

Expression Of Melanoma Antigen Genes A11 And A12 In Non-Small Cell Lung Cancer, Gondo Mastutik, Alphania Rahniayu, Isnin Anang Marhana, Mochamad Amin, Heru Fajar Trianto, Reny I'Tishom

Folia Medica Indonesiana

Highlights: 1. In this study, new primers designed using the semi-nested polymerase chain reaction (PCR) method were utilized to identify MAGE-A11 and MAGE-A12 expressions in specimens collected from core biopsy, forcep biopsy, and bronchoalveolar lavage. 2. The histopathological analysis revealed positive expressions of MAGE-A11 and MAGE-A12 in specimens diagnosed with non-small cell lung cancer (NSCLC) as well as in specimens with no malignant cells. 3. This study provides evidence indicating that the detection of messenger ribonucleic acid (mRNA) of MAGE-A11 and MAGE-A12 by nested reverse transcription PCR can improve the accuracy of lung cancer diagnosis. Abstract The melanoma antigen gene …

Differences In The Development Of Language And Social Independence In Children With Speech Delay And Sensorineural Hearing Loss Based On The Age For Early Intervention And The Duration Of Auditory-Verbal Therapy, Zamrotu Iva Purwanti, Achmad Chusnu Romdhoni, Ahmad Suryawan, Nyilo Purnami, Ninuk Dwi Ariningtyas

Folia Medica Indonesiana

Highlights : • This study explored the significance of auditory-verbal therapy as an early intervention for children with speech delay and sensorineural hearing loss, a topic that deserves further research in developing countries such as Indonesia. • The findings highlight the significance of age and therapy duration on the language development of children with speech delay and sensorineural hearing loss. Abstract Speech delay is primarily attributed to sensorineural hearing loss, which may significantly impact a child's language development and social independence. Consistent and periodic auditory-verbal therapy as an early intervention has the potential to positively influence language development, thereby fostering …

Ascorbate And Alpha-Tocopherol Mitigate Toxic Pathological Changes In Adult Wistar Rats Exposed To Cypermethrin, Temidayo Daniel Adeniyi, Akinpelu Moronkeji, Osetohanmen Flourish Ralph-Okhiria

Folia Medica Indonesiana

The excessive and uncontrolled use of pyrethroids, such as cypermethrin (CP), for pest control in Nigeria could adversely affect humans. This study aimed to investigate the oxidative stress response to cypermethrin exposure, focusing on measuring the parameters (i.e., malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT)) and the potential therapeutic effects of single and co-administration of ascorbate and alpha-tocopherol. The lungs and hearts of the animals were histologically examined for cypermethrin-induced cytopathic changes. Twenty-five adult male Wistar rats weighing 180–200 g were randomly assigned to five groups, each consisting of five animals. Group I was the control …

Development Of Discharge Planning For Stroke Patients, Muhammad Imron Rosadi, Fitri Arofiati

Folia Medica Indonesiana

Highlights: 1. Given the frequent long-term complications of stroke, this study identified the ideal approach to discharge planning to improve the quality of life of patients and hospital care. 2. This study provides evidence supporting the effectiveness of a conventional discharge planning approach that incorporates specific educational intervention with interactive learning through audiovisual media. 3. The approaches presented in this study may offer valuable perspectives on enhancing health service provisions, particularly regarding the discharge planning process for nurses. Abstract The quality improvement of discharge planning is essential throughout the development of discharge planning, which guarantees a seamless transition of care …

The Ppp1r15 Family Of Eif2-Alpha Phosphatase Targeting Subunits (Gadd34 And Crep), Danielle Hicks, Krithika Giresh, Lisa A. Wrischnik, Douglas C. Weiser

Pacific Faculty Work

The vertebrate PPP1R15 family consists of the proteins GADD34 (growth arrest and DNA damage-inducible protein 34, the product of the PPP1R15A gene) and CReP (constitutive repressor of eIF2α phosphorylation, the product of the PPP1R15B gene), both of which function as targeting/regulatory subunits for protein phosphatase 1 (PP1) by regulating subcellular localization, modulating substrate specificity and assembling complexes with target proteins. The primary cellular function of these proteins is to facilitate the dephosphorylation of eukaryotic initiation factor 2-alpha (eIF2α) by PP1 during cell stress. In this review, we will provide a comprehensive overview of the cellular function, biochemistry and pharmacology of …

Revolutionizing Attention Training In Autism Spectrum Disorder: Pioneering Virtual Reality And Artificial Intelligence, Bhavya Sri Sanku, Selena He, Joy Li

Master of Science in Computer Science Theses

In the realm of educational technology, attention training plays a critical role in tailoring learning experiences to individual needs, especially for learners with autism spectrum disorder (ASD). This study presents an advanced framework that provides insights into the efficacy of reinforcement strategies by predicting their impact on attention enhancement in educational virtual reality (VR) settings, utilizing physiological biomarkers such as eye-tracking (ET), heart rate (HR), and electrodermal activity (EDA). A comprehensive comparative analysis was undertaken to evaluate the performance metrics of various machine learning (ML) and deep learning (DL) algorithms. The results showcased the robustness of gradient boosting (GB) and …

Microstructural Alterations Of Major Thalamic Nuclei In The Chronic Pediatric Spinal Cord Injured Population, K. Kang, K. Fleming, A. Sathe, J. Muller, J. Harrop, D. Middleton, J. Heller, A. Sharan, F. Mohamed, L. Krisa, M. Alizadeh

Department of Radiology Faculty Papers

BACKGROUND: The brain undergoes reorganization following spinal cord injury (SCI), but little is known about how the thalamus is affected in pediatric SCIs.

PURPOSE: To characterize microstructural alterations in the thalamus after SCI with diffusion tensor imaging (DTI) metrics.

METHODS: 18 pediatric participants with chronic SCI (8-20 years) were stratified using the American Spinal Injury Association Impairment Scale (AIS) into groups: A, B, and C/D. DTI of the brain used a 3 T Siemens Verio MRI using the parameters: 20 directions, number of averages = 3, b = 1000 s/mm

DATA ANALYSIS: DTI metrics were acquired by superimposing the AAL3 …

George Mincey, Jr.

African American Funeral Programs

Program for the Funeral Service of George Mincey Jr., held at Ben Samuel Hill Memorial Chapel on December 10, 2023.

Reimagining A Caregiver-Friendly Society, Jodi L. Southerland

Journal of Appalachian Health

Demographic aging is accelerating in the Appalachian Region, resulting in a growing proportion of caregivers living in areas that lack services to support their needs. Strategies are urgently needed in Appalachia to address deficiencies in the region’s long-term supports and services for older adults and their caregivers. Strengthening equitable access to care and community supports for family caregivers is a policy priority for state and community leaders in Appalachia.

The Effect Of Wildfires On Human Health, Samantha Mccord, Abigail Akamine, Branden Kadlubowski, Jack Hutchins, Maria Nguyen, Brianna Lu, Joshua Honaker, Karen Kier

Pharmacy and Wellness Review

On average, 70,000 wildfires occur each year in the United States (US). Given the rise in the frequency and severity of wildfire destruction observed in recent decades, it is crucial for US healthcare providers to be aware of the risks associated with wildfire smoke exposure. The majority of fire deaths are caused by inhalation of hazardous air pollutants (HAPs), including carbon monoxide (CO) and cyanide (CN), which can debilitate victims and impair their ability to successfully escape the flames. Research indicates that an increased number of visits to the emergency department, occurring two to three days after a wildfire incident, …

Elevidys: A Novel Gene Therapy For The Treatment Of Duchenne Muscular Dystrophy, Reese Weissenfluh, Joshua Boggs, Elizabeth Sartschev, Allison Provenzale, Marisa Petrunich, Brianna Lu, Joshua Honaker, Claire Marasco

Pharmacy and Wellness Review

Duchenne Muscular Dystrophy (DMD) is a severe muscle-wasting disease caused by dystrophin gene mutations. DMD occurs in one of 3,500 male live-born infants and has one of the highest prevalence of severe congenital myopathies. Two ongoing clinical trials have contributed to the United States (US) Food and Drug Administration’s (FDA) accelerated approval of Elevidys (delandistrogene moxeparvovec), a promising drug to treat DMD. Elevidys, a recombinant adeno-associated viral (rAA V) vector-based gene therapy, gained FDA approval based on findings from the ENDEA VOR trial (NCT04626674) and EMBARK trial (NCT05096221). The phase 1 ENDEA VOR trial focused on evaluating changes in dystrophin …

Chemical Characteristics Of Artificial Plastic Plants And The Presence Of Hazardous Elements From The Recycling Of Electrical And Electronic Waste, Andrew Turner, Montserrat Filella

School of Geography, Earth and Environmental Sciences

Because of their convenience, the demand for decorative plastic plants has been increasing over recent years. However, no information exists on the origin or nature of the polymers employed or the type of additives used in order to understand potential environmental impacts and inform safe and sustainable disposal or recycling practices. In this study, 203 parts or offcuts from 175 plastic plants acquired from European shops and venues have been analysed by X-ray fluorescence spectrometry to determine elemental content, while a selection has been analysed by infrared spectrometry to establish polymer type. The (usually green) moulded components (n = 159) …

Free-Radical Scavenging Activity And Total Phenolic Compounds Of Red And Green Poinsettia Leaves (Euphorbia Pulcherrima Willd.) From Lombok Island, Handa Muliasari, Baiq Sopiah, Emmy Yuanita, Baiq Nila Sari Ningsih

Makara Journal of Science

To determine the free-radical scavenging activity and total phenolic content of the ethanol extract of Poinsettia leaves (Euphorbia pulcherrima Willd.) from Lombok Island, we used the 1,1-diphenyl-2-picrylhydrazyl method and expressed the total phenolic content as gallic acid equivalent (GAE) per gram of ethanol extract. The results show the strong antioxidant activity (79.77 ppm) of the ethanol extract of red Poinsettia leaves and the moderate antioxidant activity of green Poinsettia leaves (118.350 ppm). The ethanol extracts of red and green Poinsettia leaves possessed an average of 63.276 ± 0.228 and 22.715 ± 0.090 mg GAE/g extract total phenolic contents, respectively. …

Detection Of Prions In The Urine Of Patients Affected By Sporadic Creutzfeldt-Jakob Disease, M Talke

Faculty, Staff and Student Publications

Objective

Currently, it is unknown whether infectious prions are present in peripheral tissues and biological fluids of patients affected by sporadic Creutzfeldt–Jakob disease (sCJD), the most common prion disorder in humans. This represents a potential risk for inter‐individual prion infection. The main goal of this study was to evaluate the presence of prions in urine of patients suffering from the major subtypes of sCJD.

Methods

Urine samples from sCJD patients spanning the six major subtypes were tested. As controls, we used urine samples from people affected by other neurological or neurodegenerative diseases as well as healthy controls. These samples were …

Global Ethics, Religious Liberty, And Freedom Of Information Access, Paul A. Hartog

The Christian Librarian

Devout Christians work in a spectrum of library settings (including public libraries), networked by globalized information access. By nature of their employment, these librarians assist patrons in accessing and retrieving information that challenges or conflicts with a biblical worldview. How can one defend taking such an active role in this seeming contradiction? This article maintains that Christian commitment may not only co-exist with the freedom of information access but may also support it as a universal human right in our globalized, pluralistic context. To make the case, the essay contrasts two varying accounts of Global Ethics (differing in their view …

Front Matter Vol.59 No.4 [12/2023], Folia Medica Indonesiana

Folia Medica Indonesiana

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Lymphocyte Count And Sars-Cov-2 Antibody Level In Healthy Donors' Blood At An Indonesian Blood Transfusion Center, Adelia Gita Prasasti, Evy Diah Woelansari, Suhariyadi, Anita Dwi Anggraini

Folia Medica Indonesiana

Highlights: 1. It is essential to conduct research on SARS-CoV-2 for the purpose of acquiring further understanding, especially concerning the production of antibodies examined using antibody titer blood tests. 2. Although the relationship between the examined variables is not significant, this study offers valuable information on blood test results after the COVID-19 vaccination, which can serve as scientific evidence for further research. Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a virus that infects the respiratory system by attacking the mucous and epithelial cells. This infection commonly leads to an increase in lymphocyte count as an immune response to …

An In Vitro Assay Reveals The Anti-Aging Properties Of Temulawak Extract (Curcuma Xanthorrhiza L.), Teresa Liliana Wargasetia, Wahyu Widowati, Anis Syabani Muthmainnah, Rizal

Folia Medica Indonesiana

Highlights: 1. This study investigated the potential of temulawak extract as a cost-effective option for cosmeceutical applications in the treatment of aging. 2. Temulawak extract was found to have the ability to inhibit elastase, hyaluronidase, and tyrosinase activities, thus making it a suitable option for cosmeceutical applications. Abstract Aging is the gradual loss of a tissue's capacity to heal and maintain normal or physiological form and function. Elastase, hyaluronidase, and tyrosinase are the enzymes that contribute to the process of skin aging. The anti-aging effect is connected to the inhibition of these enzymes' activities. Numerous medicinal plants with active metabolites …

Maternal Mid-Upper Arm Circumference As A Screening Tool To Predict Infant Birth Weight, Muhammad Rais Fathurrachman, Sri Umijati, Eighty Mardiyan Kurniawati, Bagus Setyoboedi

Folia Medica Indonesiana

Highlights: 1. This study investigated the correlation between maternal mid-upper arm circumference and infant birth weight, aiming to present a different outcome compared to previous research. 2. The study's findings offer data suggesting that mid-upper arm circumference can serve as a screening tool for predicting infant birth weight. Abstract Mid-upper arm circumference (MUAC) is commonly used for assessing chronic energy deficiency in women of childbearing age. The measurement of MUAC during pregnancy mainly serves as early detection of potential low birth weight. However, certain studies have indicated no significant correlation between maternal MUAC and birth weight. Therefore, this study aimed …

Histological Study Of The Restorative Effect Of Roselle (Hibiscus Sabdariffa Linn.) Tea On The Digestive Organs Of Monosodium Glutamate-Induced Mice (Mus Musculus Linn.), Kanigara Anupama Sistra, Ngurah Intan Wiratmini, A. A.S.A. Sukmaningsih

Folia Medica Indonesiana

Highlights: • This original study examined the antioxidant compounds derived from naturally sourced Hibiscus sabdariffa calyx. • The findings demonstrated that roselle tea offers a viable and cost-effective solution for repairing histological damage to the digestive organs induced by monosodium glutamate. Abstract Monosodium glutamate (MSG) is a commonly used synthetic additive for enhancing food flavor. Excessive use of MSG can cause cytotoxic effects, which disrupt the balance of oxidative stress and free radicals in the body, particularly in the human digestive system. Roselle (Hibiscus sabdariffa) is a plant with red petals renowned for its abundance of beneficial compounds, including polyphenols, …

Thrombocytopenia As A Clinical Biomarker Of Retinopathy Of Prematurity, I Wayan Eka Sutyawan, Ni Made Ayu Surasmiati, Putu Anindya Agrasidi, Priscilla Dwianggita, Stephanus Anggara Anggara

Folia Medica Indonesiana

Highlights: • This is the first systematic review investigating thrombocytopenia and its association with retinopathy of prematurity. • Thrombocytopenia can be a useful clinical biomarker in retinopathy of prematurity screening, considering the quick, affordable, and widespread availability of the examination. Abstract Retinopathy of prematurity (ROP) is the primary cause of childhood blindness. It arises from the underdevelopment of retinal blood vessels in premature infants. Platelets have a vital function in the regulation of angiogenesis. Thus, thrombocytopenia may contribute to the progression of ROP. The objective of this systematic study was to examine the relationship between thrombocytopenia and ROP. The PubMed …

Assessment Of Seasonal Variation In Heavy Metal Status Of A Lotic Ecosystem In Federal Capital Territory, Abuja, North Central Nigeria, Aminu Ja’Afar Adano, Nengak Danjuma Marcus, Joshua Ibrahim Magaji, Obaje Daniel Opaluwa

Makara Journal of Science

The concentrations of Cu, Zn, Fe, Cd, Co, Cr, and Mn and their seasonal variations in water samples from the Wupa River, Abuja, Nigeria, were studied through the atomic absorption spectrophotometric method to determine the suitability of the water for domestic usage and identify potential sources of contamination. Sixty samples were collected during both dry and wet seasons. The respective metal concentrations (in mg/dm³) in the dry and wet seasons were as follows: Cu (0.023 ± 0.022, 0.023 ± 0.026), Zn (0.104 ± 0.039, 0.158 ± 0.085), Fe (0.350 ± 0.097, 0.3630.103), Cd (not detectable), Co (not detectable), …

Relation Of Salivary Alpha-Amylase (Saa) Concentration To Fatigue Biomarkers In Palm Oil Office Workers In Jambi Province: Preliminary Study, David Kusmawan, Willia Novita Eka Rini, Wahyu Indah Dewi Aurora

Makara Journal of Science

The salivary α-amylase (sAA) concentration has a potential role as a biological indicator of occupational fatigue. This study aimed to determine the levels of sAA and its influencing factors. This research used a cross-sectional design with a sample of 40 office staff respondents at PT. X (Persero). Mental workload (MWL), sleep quality, and occupational fatigue were measured using the NASA-Total Load Index (TLX), Pittsburgh Sleep Quality Index, and Industrial Fatigue Research Committee, respectively. Meanwhile, the basic sAA levels was measured through the sandwich enzyme-linked immunosorbent assay method using the Bioenzy® Kit Assay. Descriptive analysis showed that the workers were mostly …