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2023

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Bedford Springs Resort: A Political And Social Annex Of Antebellum America: 1840-1860, Sara Grace Davis-Leonard Dec 2023

Bedford Springs Resort: A Political And Social Annex Of Antebellum America: 1840-1860, Sara Grace Davis-Leonard

Doctoral Dissertations and Projects

Antebellum America has been described as a period of turbulence for the nation as the North and the South grew farther apart through sectionalism. While voters relied upon the increasing partisan press to inform them of debates in Washington and the often-deliberate decision to forgo the ultimate decision on slavery, in private politicians forged friendships through social events such as parties and dinners. When the Congressional session ended in early summer, politicians often accompanied by their families would travel north to Saratoga Springs or west to the much cooler climates of the mountain resorts: Bedford Springs, White Sulphur Springs, Warm …

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Prmt Blockade Induces Defective Dna Replication Stress Response And Synergizes With Parp Inhibition, Yang Li, Lacey E Dobrolecki, Christina Sallas, Xudong Zhang, Travis D Kerr, Deepa Bisht, Yalong Wang, Sharad Awasthi, Babita Kaundal, Siqi Wu, Weiyi Peng, Marc L Mendillo, Yiling Lu, Collene R Jeter, Guang Peng, Jinsong Liu, Shannon N Westin, Anil K Sood, Michael T Lewis, Jishnu Das, S Stephen Yi, Mark T Bedford, Daniel J Mcgrail, Nidhi Sahni Dec 2023

Prmt Blockade Induces Defective Dna Replication Stress Response And Synergizes With Parp Inhibition, Yang Li, Lacey E Dobrolecki, Christina Sallas, Xudong Zhang, Travis D Kerr, Deepa Bisht, Yalong Wang, Sharad Awasthi, Babita Kaundal, Siqi Wu, Weiyi Peng, Marc L Mendillo, Yiling Lu, Collene R Jeter, Guang Peng, Jinsong Liu, Shannon N Westin, Anil K Sood, Michael T Lewis, Jishnu Das, S Stephen Yi, Mark T Bedford, Daniel J Mcgrail, Nidhi Sahni

Faculty, Staff and Student Publications

Multiple cancers exhibit aberrant protein arginine methylation by both type I arginine methyltransferases, predominately protein arginine methyltransferase 1 (PRMT1) and to a lesser extent PRMT4, and by type II PRMTs, predominately PRMT5. Here, we perform targeted proteomics following inhibition of PRMT1, PRMT4, and PRMT5 across 12 cancer cell lines. We find that inhibition of type I and II PRMTs suppresses phosphorylated and total ATR in cancer cells. Loss of ATR from PRMT inhibition results in defective DNA replication stress response activation, including from PARP inhibitors. Inhibition of type I and II PRMTs is synergistic with PARP inhibition regardless of homologous …

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Life, The Genome And Everything, Susan M Rosenberg Dec 2023

Life, The Genome And Everything, Susan M Rosenberg

Faculty, Staff and Students Publications

In this issue of the Journal of Bacteriology, N. J. Bonde, E. A. Wood, K. S. Myers, M. Place, J. L. Keck, and M. M. Cox (J Bacteriol 205:e00184-23, 2023, https://doi.org/10.1128/jb.00184-23) used an unbiased transposon-sequencing (Tn-seq) screen to identify proteins required for life when cells lose the RecG branched-DNA helicase (synthetic lethality). The proteins’ identities indicate pathways that prevent endogenous DNA damage, pathways that prevent its homology-directed repair (HDR) “strand-exchange” intermediates between sister chromosomes, and pathways that resolve those intermediates. All avoid intermediate pile-up, which blocks chromosome segregation, causing “death-by-recombination.” DNA damage is managed to regulate crucial but …

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A Mixed-Methods Inquiry Into Pastors' Knowledge And Responses To Human Trafficking In Their Congregations In The Baptist Convention Of Maryland/Delaware, Denise A. Beck Dec 2023

A Mixed-Methods Inquiry Into Pastors' Knowledge And Responses To Human Trafficking In Their Congregations In The Baptist Convention Of Maryland/Delaware, Denise A. Beck

Doctoral Dissertations and Projects

The purpose of this mixed-methods study was to discover the knowledge of human trafficking of the pastors in the Baptist Convention of Maryland/Delaware churches and their responses to this crime. The guiding theory was the words of Jesus in Exodus: Chapter 3 concerning slavery and the tribulations of Israelites. A questionnaire provided enlightenment regarding the levels of knowledge in the church communities, how pastors viewed it, the methods by which they received the information, and how they responded to it. This study reflected a gap in the knowledge of pastors in their congregations. The data were collected through emails and …

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Mindfulness For The Reduction Of Anxiety, Stress, And Depression In The Preservice Teacher Community, Shelley R. Crampton Dec 2023

Mindfulness For The Reduction Of Anxiety, Stress, And Depression In The Preservice Teacher Community, Shelley R. Crampton

Doctoral Dissertations and Projects

Teachers and students alike suffer from anxiety, stress, and depression. Mindfulness-based strategies have been indicated to help teachers and students deal with stress, anxiety, and depression. Teachers often report not wishing to add more learning strategies to their packed schedules and workload. Education in mindfulness is not easily accessible due to the time constraints of this overworked population. The criteria for participation in the study required the college students in preservice education classes to be over 18 years old, enrolled in the teacher education program, and not have participated in any mindfulness in the last six months. The study is …

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With Or Without The Table, We Gather: Reinforcing Innate Resiliencies In The African American Family, Jessica L. Stevens-Eddy Dec 2023

With Or Without The Table, We Gather: Reinforcing Innate Resiliencies In The African American Family, Jessica L. Stevens-Eddy

Doctoral Dissertations and Projects

This quantitative study aims to determine whether food-sharing (gathering to eat) can be considered a suitable medium to facilitate increased cohesion within African American families. This study focuses on informal food-sharing as an extension of formal meal-sharing. Previous research links consistent formal meal-sharing to positive and secure identity development, better familial attachment, and improved family cohesion. These practices leave a lasting, detrimental impact on the African American family model. Additional barriers to some African American family meal-sharing practices include working extended and atypical work hours, food insecurity, and poor familial communication. There is a lack of research concerning the impact …

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Preserving Hope Through Youth Attendance At New Canaan Baptist Church, David C. Turner Dec 2023

Preserving Hope Through Youth Attendance At New Canaan Baptist Church, David C. Turner

Doctoral Dissertations and Projects

The biblical perspective of training up a child in the way to go provides the foundation for mentoring to influence youth success. This thesis project applies a needs analysis to fulfill the effort to preserve hope through youth attendance at New Canaan Baptist Church. No secular or spiritual mentorship program exists for African American male youth in Chester, Georgia. This qualitative study used surveys to query the beliefs of African American youth, church leaders, and parents about the need for a mentorship program. Findings from analyses of survey data from almost thirty participants implied the need for a community-based mentorship …

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A Case For Offering An Associate Of Fine Arts In Music At Community Colleges In Rural Northwestern And Northern Regions Of North Carolina, Frieda Eakins Dec 2023

A Case For Offering An Associate Of Fine Arts In Music At Community Colleges In Rural Northwestern And Northern Regions Of North Carolina, Frieda Eakins

Doctoral Dissertations and Projects

This qualitative method research paper with survey design identifies the need to implement an associate in fine arts degree in music at community colleges located in the rural northwestern and northern regions of North Carolina. A music degree would provide early college students with music courses comparable to those offered in traditional area high schools and greater accessibility for a diverse student population of community college students. At the inception of this study, early college high school programs in rural northwestern and northern regions of North Carolina did not offer music courses. Students in these programs relied on the community …

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A Phenomenological Study In Understanding African American Spiritual Leaders And The Black Church On Elder Abuse, Cassandra R. Downey Dec 2023

A Phenomenological Study In Understanding African American Spiritual Leaders And The Black Church On Elder Abuse, Cassandra R. Downey

Doctoral Dissertations and Projects

This qualitative study described how the Black Church and African American Spiritual Leaders in Milwaukee, Wisconsin, understood the issue of elder abuse and the Black Church's role in navigating education and resources to those who are victims or at risk. African-American Spiritual Leaders' role and leadership are integral in combating elder abuse among their older members of the church and society. African Americans have always placed a significant portion of their support in the church and frequently turn to them before considering other options. Acknowledging the church's and spiritual leaders' involvement in comprehending the awareness of elder maltreatment is essential …

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The Impact Of Moral Injury On Character Identity For Divorced Catholics: A Character Domain Perspective, Mary Susan Mcauliff Dec 2023

The Impact Of Moral Injury On Character Identity For Divorced Catholics: A Character Domain Perspective, Mary Susan Mcauliff

Doctoral Dissertations and Projects

Catholics who are faithful to the teachings of the Catholic Church on the indissolubility of marriage and who experience a civil divorce are at high risk for moral injury. This study was anchored on a character domain theoretical framework, and it investigated the impact of moral injury on character identity (measured by self-discrepancy) through the mediation of the perception of suffering. Religiosity was explored as a moderator for the relationships of moral injury to perception of suffering, perception of suffering to character identity, and moral injury to character identity. Participants (N = 251) were recruited from social media groups, various …

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A Correlational Study: Second-Chair Leaders' Level 5 Leadership Score And Church Growth Among Southern Baptist Megachurches, Martin Benjamin Lovvorn Dec 2023

A Correlational Study: Second-Chair Leaders' Level 5 Leadership Score And Church Growth Among Southern Baptist Megachurches, Martin Benjamin Lovvorn

Doctoral Dissertations and Projects

As the church strives to overcome seemingly insurmountable challenges and navigate tumultuous times to fulfill its Great Commission, church leaders must strive to understand the type of leadership required to best accomplish their kingdom work. In researching the type of pastoral leadership that will most effectively build the church of Jesus Christ and advance his kingdom, much work has been dedicated to examining the leadership styles and influence of senior or lead pastors. However, few studies have explored the influence of second-chair pastoral leaders (SCPLs). This study is the first to quantitatively examine whether SCPLs who demonstrate the personal humility …

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A Phenomenological Study Of African-American Clergys’ Experiences With Mental Health, Rosalind R. Smith Dec 2023

A Phenomenological Study Of African-American Clergys’ Experiences With Mental Health, Rosalind R. Smith

Doctoral Dissertations and Projects

The purpose of this hermeneutical phenomenological qualitative study was to describe African-American clergy’s lived experiences with mental health and mental health’s influence on the construction of their teachings, sermons, and church practice. The goal was to use interpretation to bring to light to an underlying coherence of actions of a group of people. This study reduced individual African-American clergy beliefs regarding mental health to a universal understanding. There were four philosophical assumptions in this study: 1) a search for wisdom to understand the phenomenon of African-American clergy’s lived experiences with mental health influence their teachings, sermons, and church practice, 2) …

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The Lived Experiences Of The Newly Graduated Generation "Z": Registered Nurse Entering The Intensive Care Unit, Matthew Robert Loveitt Dec 2023

The Lived Experiences Of The Newly Graduated Generation "Z": Registered Nurse Entering The Intensive Care Unit, Matthew Robert Loveitt

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to illuminate, understand, and describe the meaning of the lived experiences of Gen Z new graduate registered nurses (NGRNs) transitioning directly into the ICU in their first position as registered nurses. Duchscher’s stages of transitional theory and the Strauss-Howe generational theory provided this study’s theoretical framework, focusing on the Gen Z NGRN transition into practice. This study answered the following central research question: What is the lived experience of Gen Z NGRNs transitioning into the ICU work environment employed in their first position as registered nurses? Data were collected for this study …

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A Phenomenological Approach: How Hopelessness Affects Achievement In The Areas Of Socio-Economic, Criminality, And Educational Success Within The African American Community, Shawn A. Parker Dec 2023

A Phenomenological Approach: How Hopelessness Affects Achievement In The Areas Of Socio-Economic, Criminality, And Educational Success Within The African American Community, Shawn A. Parker

Doctoral Dissertations and Projects

This phenomenological study was designed to examine how the concept of hope or lack thereof has an impact on the negative discrepancies in the areas of education, criminal behavior, and socio-economic status among African Americans as it compares to Whites. There may be other ethnicities who have significant inconsistencies as well, but for the sack of this study, the comparisons were primarily among African Americans and Whites. The theory guiding this study is the psychodynamic approach. This approach was guided by Sigmond Freud’s desire to understand human behavior; provided a path to studying the events of the past and present …

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Beyond Acculturation And Resilience: International Students Navigating Shame And Self-Concept, Shauna Thompson Dec 2023

Beyond Acculturation And Resilience: International Students Navigating Shame And Self-Concept, Shauna Thompson

Doctoral Dissertations and Projects

This study highlights the unique experiences of international students while they pursue higher education, manage adjustment issues, and navigate internal struggles. To explore whether English proficiency and family expectations correlate with self-concept and acculturation resilience, this study focused on the acculturation process, incorporating aspects of shame and self-concept that contribute to a student’s motivation and resilience. International students commonly face academic and personal challenges while adjusting to an environment that requires fluency in English. Additionally, many experience the pressure of high expectations from their families in their countries of origin. This study used a sociocultural approach to explore how international …

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Clawhammer: Vincent A. Witcher And Guerrilla Warfare In Civil War Southern Appalachia, Melanie Greer Storie Dec 2023

Clawhammer: Vincent A. Witcher And Guerrilla Warfare In Civil War Southern Appalachia, Melanie Greer Storie

Doctoral Dissertations and Projects

Vincent A. Witcher, the subject of this dissertation, is largely unknown to Civil War historians. He is rarely mentioned, and when he is, it is primarily in connection with J.E.B. Stuart’s cavalry on the third day of the Battle of Gettysburg. Without the 1886 New York Times article and the resulting lawsuit, Witcher might have faded away as a historical footnote for his minor role at Gettysburg. However, this dissertation argues that his libel suit represents a microcosm of the complicated nature of guerrilla warfare during the Civil War. Through a lens of memory and regional history, the Witcher case …

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The Need For A Spiritual Reboot In The Youth Of Great Commission Church, Jean Max B St Louis Dec 2023

The Need For A Spiritual Reboot In The Youth Of Great Commission Church, Jean Max B St Louis

Doctoral Dissertations and Projects

The decline of the youth attendance is evident in many Protestant churches. This research paper examined forty-three young believers from three Haitian Baptist churches, respectively, located in Brooklyn, Queens, and the Bronx. These data results help develop a suitable spiritual program that includes the six key influencing factors for spiritual growth: discipleship, mentoring, parental influence, church attendance, personal devotion, and ministerial involvement. This spiritual program was tested on a small group of young people from Great Commission Church in Queens. This research uses a mixed-method methodology, which is a combination of qualitative and quantitative methods to analyze the data. The …

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Apologetic Knowledge: The Modern Church Planter, Matthew Dilley Dec 2023

Apologetic Knowledge: The Modern Church Planter, Matthew Dilley

Doctoral Dissertations and Projects

This project addresses a critical need within the ministry field, focusing on pastors affiliated with the church planting networks Excel Leadership Network and Transformation Ministries. The context is shaped by the COVID-19 pandemic's impact on church planting, with a shift to online services and emerging challenges in ministry. The problem is the significant lack of knowledge of apologetics among church planters, hindering their ability to effectively articulate and defend the Christian faith in today's postmodern world, particularly when engaging with non-believers. This DMIN action research project aims to create a concise video curriculum that equips pastors with fundamental apologetics knowledge. …

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How Does Nurse-To-Patient Ratio Impact Patient Outcomes In Adults, 18 Years And Older, That Are Admitted To Hospitals Around The World: An Integrative Review, Bre' Bryant Dec 2023

How Does Nurse-To-Patient Ratio Impact Patient Outcomes In Adults, 18 Years And Older, That Are Admitted To Hospitals Around The World: An Integrative Review, Bre' Bryant

Doctoral Dissertations and Projects

The field of nursing, known as the heart of health care, impacts individuals throughout every season of life: from the first cry to the last breath. It matters not how advanced the world might become; the calming presence of a nurse is irreplaceable. Considering the value of nurses, adequate work settings and staffing ratios is essential for care provision. Current practice is lacking, focusing heavily on patient satisfaction while staff contentment is not always addressed. Ratios are being increased, changing the way nurses provide care. The industry calls nurses into action to provide care that is efficient, effective, and safe. …

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The Intersection Of The Sibling Relationship, Parental Divorce, And Mental Health Symptoms, Taylor A. Bufton Dec 2023

The Intersection Of The Sibling Relationship, Parental Divorce, And Mental Health Symptoms, Taylor A. Bufton

Doctoral Dissertations and Projects

Although sibling relationships and parental divorce are two popular areas of study, few research studies have focused on their relationship. In this quantitative study, the researcher explored the relationship between sibling relationship quality and parental divorce conflict, as well as the relationship between perceived sibling relationship quality during parental divorce and mental health in adulthood. The participant sample included 64 adults who experienced parental divorce in childhood with at least one sibling. Participants were required to complete a demographics questionnaire, the Post-Divorce Parental Conflict Scale (PPCS), the Lifespan Sibling Relationship Scale (LSRS), and the General Health Questionnaire (GHQ-12). A Pearson’s …

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A New Mother’S Cry: Analyzing Traditional Social Support Versus Online Social Support In Relation To The Postpartum Crisis, Emily Hughes Dec 2023

A New Mother’S Cry: Analyzing Traditional Social Support Versus Online Social Support In Relation To The Postpartum Crisis, Emily Hughes

Doctoral Dissertations and Projects

The present study examines the gap that remains involving the transition from traditional to online social support that many mothers have participated in and how this change in communication methods during postpartum recovery may contribute to mental health disorders. This qualitative study aims to examine the differences in lived experiences among mothers regarding in-person and online forms of social support and how these experiences may impact a new mother’s mental well-being. Based on previous research, the present study hypothesizes that a more significant amount of online social support compared to in-person support will result in a detriment to a new …

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A Provident Mindset To Impostor Phenomenon Of In-Service Music Educators, Jerry Mark Buttrum Dec 2023

A Provident Mindset To Impostor Phenomenon Of In-Service Music Educators, Jerry Mark Buttrum

Doctoral Dissertations and Projects

Impostor Phenomenon (IP) is a psychological construct that affects many high-achieving professionals to doubt their competence, intelligence, and self-worth. As a result, many with IP will overwork and self-sabotage as they constantly feel like a fraud within their profession or daily lives. Despite previous literature and research with pre-service and graduate students in music education, more data on the IP of In-Service Music Educators still needs to be collected. Therefore, the purpose of the current study is to examine the provident mindset of IP among In-Service Music Educators. A quantitative MANOVA design method evaluated this phenomenon. The study collected quantitative …

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A Qualitative Descriptive Study: Exploring Organizational Justice, Equity, Diversity, And Inclusion In The Workplace For Individuals With A History Of Criminal Behavior, Heather Danielle Morton Dec 2023

A Qualitative Descriptive Study: Exploring Organizational Justice, Equity, Diversity, And Inclusion In The Workplace For Individuals With A History Of Criminal Behavior, Heather Danielle Morton

Doctoral Dissertations and Projects

Individuals with a history of criminal behavior often experience difficulties finding employment once labeled a criminal by society. Maintaining stable employment post-release has been found to lower recidivism rates, thus supporting safer communities. In concert, positive experiences with equity and inclusion in the workplace have further been found to support stronger social identities and belonging in the workplace. Currently, no study has specifically examined the impact of organizational justice, equity, diversity, and inclusion implementation and practices in the workplace among individuals with a history of criminal behavior. Therefore, the purpose of this qualitative descriptive study was to better understand the …

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The Transformation Of Rural Elementary Classroom English Language Teachers During Distance Learning: A Transcendental Phenomenological Study, Cecilia Frazier Salzer Dec 2023

The Transformation Of Rural Elementary Classroom English Language Teachers During Distance Learning: A Transcendental Phenomenological Study, Cecilia Frazier Salzer

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to understand the transformation of rural elementary classroom teachers who transitioned to distance learning with English learners (ELs) during the COVID-19 pandemic in the California Central Valley. The theory guiding this study is Mezirow’s transformative learning theory. At the same time the conceptual framework is Technology, Pedagogy, and Content Knowledge (TPACK), as both will ascribe meaning to how EL teachers transformed their perspectives, assumptions, feelings, and judgments while conducting distance learning. The research question guiding this study is: What transformation did teachers experience while providing distance learning instruction to rural elementary English …

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Increasing The Number Of High School Seniors Meeting The South Carolina "Profile Of A Graduate" Mandate, Cecil Bonner Dec 2023

Increasing The Number Of High School Seniors Meeting The South Carolina "Profile Of A Graduate" Mandate, Cecil Bonner

Doctoral Dissertations and Projects

This applied study aimed to solve the problem of the inadequate number of high school seniors at Avenger Career Technology Center that meet the requirement of South Carolina's Profile of a Graduate. A multimethod approach was utilized to examine the problem of high school seniors not meeting college and career mandates. Data was collected through interviews with administrators, a focus group of ACTC students, and a quantitative survey from Avenger Career Technology Center teachers. Interviews were conducted with five administrators. A focus group of 10 students was held. Eighteen teachers completed a quantitative survey. Data were analyzed for codes and …

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Relationships Between Shame, Cognitive Distortions And Positive Relationships With Others Among Young Adults, And Changes In Shame Resulting From An Intervention Focusing On Cognitive Distortions, John E. Shanks Dec 2023

Relationships Between Shame, Cognitive Distortions And Positive Relationships With Others Among Young Adults, And Changes In Shame Resulting From An Intervention Focusing On Cognitive Distortions, John E. Shanks

Doctoral Dissertations and Projects

Experiences of shame are strongly correlated with diminished social relations in individuals of all ages. Difficult and traumatic early childhood situations and experiences such as partner abuse, sexual violence in situations with differences in status commonly lead to shame. Difficult family situations and traumatic situations also frequently result in cognitive distortions, flawed thinking which often continues through adulthood. This study evaluated the experiences of shame, satisfaction of social relations, and cognitive distortions of young adults ages 18-25 years of age. Participants included 88 young adults recruited from social media sites and email contacts. Self-report measures were used to evaluate the …

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Implementing Appropriate Use Of Technology: A Case Study On How Rural Secondary Students Approach Digital Citizenship, Jill A. Lilly Dec 2023

Implementing Appropriate Use Of Technology: A Case Study On How Rural Secondary Students Approach Digital Citizenship, Jill A. Lilly

Doctoral Dissertations and Projects

The purpose of this intrinsic case study is to discover the approach of rural secondary students regarding their attainment and practice of digital citizenship in a learning environment that utilizes technology. The theory guiding this research study is Kohlberg’s theory of moral development as it emphasizes how individuals establish their ethics and values because digital citizenship teaches students to use the Internet in an ethical and appropriate manner. The qualitative inquiry was conducted using an intrinsic case study in a small rural secondary public school. Convenience sampling was utilized, giving way to 18 adolescent participants and 10 teachers at the …

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Moral Injury: The Hidden Adversary Of War, Lashell Y. Davis Dec 2023

Moral Injury: The Hidden Adversary Of War, Lashell Y. Davis

Doctoral Dissertations and Projects

The purpose of this qualitative hermeneutic phenomenological study was to understand the lived experiences of United States Army combat veterans who have supported combat operations at least once over the past fourteen years in either Iraq or Afghanistan who self-identified as suffering from symptoms of moral injury. This study was designed to elucidate the impact of faith on resilience and coping mechanisms and broaden previous research on moral injury and whether Army leaders should identify and mitigate moral injury within the ranks. Phenomenology focuses on the interpretation and meaning of how individuals experience their world within a given context. Seven …

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Correlation Between Purposeful Patient Medication Education And Patient Experience Scores, Paula Shredl Dec 2023

Correlation Between Purposeful Patient Medication Education And Patient Experience Scores, Paula Shredl

Doctoral Dissertations and Projects

The Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) is a national grading system that is used by payors to determine patients’ perception of their hospital stay. This public benchmarking system is tied to reimbursements and encompasses several domain areas. The medication and nursing domain questions revolve around how the nursing staff explained the purpose and possible side effects of patient medication. This project targeted a medical-surgical unit in a suburban faith-based hospital that was not meeting the national benchmarks in the nursing domain. The purpose of this evidence-based practice project, which was conducted using the Iowa Model of …

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Final 2023 Residential Metals Abatement Program (Rmap) Brw/Belgrade Borrow Submittal, Pioneer Technical Services, Inc. Dec 2023

Final 2023 Residential Metals Abatement Program (Rmap) Brw/Belgrade Borrow Submittal, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

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