Digital Commons Network^™

The Representation Of Third-Party Helping Interactions In Infancy, Laura Schlingloff-Nemecz, Denis Tatone, Gergely Csibra

School of Psychology

Despite numerous findings on the sophisticated inferences that human infants draw from observing third-party helping interactions, currently there is no theoretical account of how infants come to understand such events in the first place. After reviewing the available evidence in infants, we describe an account of how human adults understand helping actions. According to this mature concept, helping is a second-order, goal-directed action aiming to increase the utility of another agent (the Helpee) via reducing the cost, or increasing the reward, of the Helpee's own goal-directed action. We then identify the cognitive prerequisites for conceiving helping in this way and …

Intouch Week Of December 11, 2023, New York Medical College

InTouch

• Key Discovery Could Offer Hope in Fight Against Alzheimer's Disease
• James Williams’ Journey from the NFL to NYMC
• Student Housing Fitness Center Gets a Makeover
• BioInc@NYMC Welcomes Marubeni America Specialty Chemicals Unit as Newest Client
• D.P.T. Class of 2025 Present Community Service Projects
• Student Spotlight: Kathleen Harwood Lead Authors Publications in Sports Medicine

Teaching Engineering Design-Based Integrated Stem In Rural Contexts: Nurturing Future Designers, Jung Han, Euisuk Sung, Todd Kelley, John Geoffrey Knowles

Publications and Research

There is a notable shift towards prioritizing the teaching of engineering design within K-12 education, coupled with a strong recommendation for engineering design-based integrated STEM education. This approach underscores the sharing of science and engineering practices as a means to facilitate the learning of various STEM disciplines. Nonetheless, the implementation of integrated STEM education in rural schools poses challenges due to constrained resources and a shortage of high-quality programs. To present a tangible instance of design-based integrated STEM education within a rural setting, this study presents a model lesson that showcases the integration of interdisciplinary problem-solving skills within a genuine …

Applications Of Implementation Science Frameworks, Models And Theories In Disparities-Focused Cancer Screening Interventions: A Scoping Review Protocol, Serena Xiong, Lisa Klesges, Michelle Doering, Rebekah J Pratt

2020-Current year OA Pubs

BACKGROUND: Implementation science (IS) frameworks, models and theories (FMTs) have gained popularity in guiding the implementation and evaluation of evidence-based interventions (EBIs) for cancer screening. However, there are significant research gaps in understanding their applications in cancer health disparities contexts. This paper outlines a scoping review protocol designed to explore the utilisation of IS FMTs in cancer screening EBIs to inform intervention designs and adaptations.

METHODS AND ANALYSIS: This scoping review protocol adheres to Arksey and O'Malley's five-step methodological framework for conducting scoping studies. Search strategies were conducted in five bibliographic databases: Ovid MEDLINE, PubMed, Scopus, Web of Science and …

Engineering Exosomes To Specifically Target The Mitochondria Of Brain Cells, Xin Yan, Xinqian Chen, Zhiying Shan, Lanrong Bi

Michigan Tech Publications

Mitochondrial dysfunction is associated with various health conditions, including cardiovascular and neurodegenerative diseases. Mitochondrial-targeting therapy aims to restore or enhance mitochondrial function to treat or alleviate these conditions. Exosomes, small vesicles that cells secrete, containing a variety of biomolecules, are critical in cell-to-cell communication and have been studied as potential therapeutic agents. Exosome-based therapy has the potential to treat both cardiovascular and neurodegenerative diseases. Combining these two approaches involves using exosomes as carriers to transport mitochondrial-targeting agents to dysfunctional or damaged mitochondria within target cells. This article presents a new technique for engineering brain-derived exosomes that target mitochondria and has …

Review Of "The #Actuallyautistic Guide To Advocacy: Step-By- Step Advice On How To Ally And Speak Up With Autistic People And The Autism Community", Jennifer M. Brady

The Christian Librarian

No abstract provided.

Rupturing Tradition: Theorizing Black Women’S Place In The Discipline Through The Disruptive Rhetoric Of Sanctuary, Celnisha Leta Dangerfield

Electronic Theses and Dissertations Archive

Black women need refuge from physical, mental, emotional and rhetorical violence. However, refuge that does not foster liberation can never offer the full protection of sanctuary. Black women uniquely understand that the only way to ensure full access to sanctuary is by circumventing place. Yet, people and scholarly disciplines overlook their valuable, experiential awareness of place. This dissertation takes an intersectional approach to place by analyzing Black women’s contributions to the rich rhetorical tradition. When we look to the past for guidance, it is easy to see Black women’s struggles are not bound by place or time. An analysis of …

Interventions To Promote Cost-Effectiveness In Adult Intensive Care Units: Consensus Statement And Considerations For Best Practice From A Multidisciplinary And Multinational Edelphi Study, Amit Kansal, Jos M. Latour, Kay Choong See, Sumeet Rai, Maurizo Cecconi, Carl Britto, Morris A Conway, Rd Savio, Vinay M. Nadkarni, B. K. Rao, Rajesh Mishra

School of Nursing and Midwifery

Background There is limited evidence to guide interventions that promote cost-effectiveness in adult intensive care units (ICU). The aim of this consensus statement is to identify globally applicable interventions for best ICU practice and provide guidance for judicious use of resources. Methods A three-round modified online Delphi process, using a web-based platform, sought consensus from 61 multidisciplinary ICU experts (physicians, nurses, allied health, administrators) from 21 countries. Round 1 was qualitative to ascertain opinions on cost-effectiveness criteria based on four key domains of high-value healthcare (foundational elements; infrastructure fundamentals; care delivery priorities; reliability and feedback). Round 2 was qualitative and …

Taxane-Based Chemotherapy Is Effective In Metastatic Appendiceal Adenocarcinoma, Julia Dansby, Aditya More, Mohammad Zeineddine, Abdelrahman Yousef, Alisha Bent, Farshid Dayyani, Robert Wolff, Michael Overman, John Paul Shen

Faculty, Staff and Student Publications

Appendiceal cancer is a rare, orphan disease with no therapies currently approved by the FDA for its treatment. Given the limited data regarding drug efficacy, these tumors have historically been treated with chemotherapy designed for colon cancer. However, an overwhelming body of molecular data has demonstrated that appendiceal adenocarcinoma is a distinct entity with key molecular differences from colon cancer, notably rare APC mutation. Recognizing that APC loss-of-function is thought to contribute to taxane resistance and that taxanes are effective in the treatment of other gastrointestinal tumors, including gastric, esophageal, and small bowel adenocarcinoma, we completed a single-center retrospective study …

Sustained Disease Control In Immune Checkpoint Blockade Responders With Microsatellite Instability-High Colorectal Cancer After Treatment Termination, Kristen Simmons, Jane V Thomas, Kaysia Ludford, Jason A Willis, Victoria S Higbie, Kanwal P S Raghav, Benny Johnson, Arvind Dasari, Bryan K Kee, Christine M Parseghian, Michael S Lee, Phat H Le, Maria P Morelli, John Paul Shen, Alisha Bent, Eduardo Vilar, Robert A Wolff, Scott Kopetz, Michael J Overman, Van Karlyle Morris

Faculty, Staff and Student Publications

Immune checkpoint inhibitors improve survival in patients with mismatch repair deficiency/microsatellite instability-high (MSI-H) colorectal cancer. The recurrence outcomes following discontinuation of immunotherapy after prolonged disease control have not been definitively reported in large series. Records from patients with advanced MSI-H colorectal cancer from The University of Texas - MD Anderson Cancer Center who received immunotherapy between 2014 and 2022 and stopped after prolonged clinical benefit were reviewed. Median progression-free and overall survival were estimated. Associations between the event of recurrence and coexisting mutations (KRAS/NRAS, BRAFV600E), metastatic organ involvement (lung, liver, lymph node, or peritoneum), metastatic timing (synchronous vs. metachronous), prior …

Feasibility, Enablers And Challenges Of Using Timeliness Metrics For Household Contact Tracing And Tb Preventive Therapy In Pakistan, Bushra Jamil, Divya Nair, Pruthu Thekkur, Neelofar Laeeq, Anum Adil, Mohammed Khogali, Rony Zachariah, Selma Dar Berger, Srinath Satyanarayana, Ajay M V Kumar

Department of Medicine

Introduction: Screening household contacts of TB patients and providing TB preventive therapy (TPT) is a key intervention to end the TB epidemic. Global and timely implementation of TPT in household contacts, however, is dismal. We adapted the 7-1-7 timeliness metric designed to evaluate and respond to infectious disease outbreaks or pandemics, and assessed the feasibility, enablers and challenges of implementing this metric for screening and management of household contacts of index patients with bacteriologically-confirmed pulmonary TB in Karachi city, Pakistan.
Methods: We conducted an explanatory mixed methods study with a quantitative component (cohort design) followed by a qualitative component (descriptive …

Employment Leave For Early Pregnancy Endings: A Biopolitical Reproductive Governance Analysis In England And Wales, Al Middlemiss, I Boncori, J Brewis, J Davies, Vl Newton

School of Nursing and Midwifery

When a pregnancy ends in England and Wales, statutory time away from paid employment is limited to circumstances where there is a live birth or stillbirth. Forms of leave, such as Maternity Leave or Paternity Leave, depend on parental status derived from the civil registration of a new person or a post-viability stillbirth. Other early pregnancy endings, such as miscarriage or abortion, do not provide specific time off work after pregnancy. This paper uses the concept of reproductive governance to analyze current and shifting biopolitical truth discourses, strategies of intervention, and modes of subjectification around post-pregnancy leaves. It shows how …

Immunoproximity Biotinylation Reveals The Axon Initial Segment Proteome, Wei Zhang, Yu Fu, Luxin Peng, Yuki Ogawa, Xiaoyun Ding, Anne Rasband, Xinyue Zhou, Maya Shelly, Matthew N Rasband, Peng Zou

Faculty, Staff and Students Publications

The axon initial segment (AIS) is a specialized neuronal compartment required for action potential generation and neuronal polarity. However, understanding the mechanisms regulating AIS structure and function has been hindered by an incomplete knowledge of its molecular composition. Here, using immuno-proximity biotinylation we further define the AIS proteome and its dynamic changes during neuronal maturation. Among the many AIS proteins identified, we show that SCRIB is highly enriched in the AIS both in vitro and in vivo, and exhibits a periodic architecture like the axonal spectrin-based cytoskeleton. We find that ankyrinG interacts with and recruits SCRIB to the AIS. However, …

Ultrafast Electronic Relaxation Pathways Of The Molecular Photoswitch Quadricyclane, Kurtis D. Borne, Joseph C. Cooper, Michael N. R. Ashfold, Julien Bachmann, Surjendu Bhattacharyya, Rebecca Boll5, Matteo Bonanomi, Michael Bosch, Carlo Callegari, Martin Centurion, Marcello Coreno, Basile F. E. Curchod, Miltcho B. Danailov, Alexander Demidovich, Michele Di Fraia, Benjamin Erk, Davide Faccialà, Raimund Feifel, Ruaridh J. G. Forbes, Christopher S. Hansen, David M. P. Holland, Rebecca A. Ingle, Roland Lindh, Lingyu Ma, Henry G. Mcghee, Sri Bhavya Muvva, Joao Pedro Figueira Nunes, Asami Odate, Shashank Pathak, Oksana Plekan, Kevin C. Prince, Primoz Rebernik, Arnaud Rouzée, Artem Rudenko, Alberto Simoncig, Richard J. Squibb, Anbu Selvam Venkatachalam, Caterina Vozzi, Peter M. Weber, Adam Kirrander, Daniel Rolles

Martin Centurion Publications

The light-induced ultrafast switching between molecular isomers norbornadiene and quadricyclane can reversibly store and release a substantial amount of chemical energy. Prior work observed signatures of ultrafast molecular dynamics in both isomers upon ultraviolet excitation but could not follow the electronic relaxation all the way back to the ground state experimentally. Here we study the electronic relaxation of quadricyclane after exciting in the ultraviolet (201 nanometres) using time-resolved gas-phase extreme ultraviolet photoelectron spectroscopy combined with non-adiabatic molecular dynamics simulations. We identify two competing pathways by which electronically excited quadricyclane molecules relax to the electronic ground state. The fast pathway (<100 femtoseconds) is distinguished by effective coupling to valence electronic states, while the slow pathway involves initial motions across Rydberg states and takes several hundred femtoseconds. Both pathways facilitate interconversion between the two isomers, albeit on different timescales, and we predict that the branching ratio of norbornadiene/ quadricyclane products immediately after returning to the electronic ground state is approximately 3:2.

Looking Into The “Dark Mirror”: Autoethnographic Reflections On The Impact Of Covid-19 And Change Fatigue On The Wellbeing Of Enabling Practitioners, Angela Jones, Susan Hopkins, Ana Larsen, Joanne Lisciandro, Anita Olds, Marguerite Westacott, Rebekah Sturniolo-Baker, Juliette Subramaniam

Research outputs 2022 to 2026

The COVID-19 pandemic brought global disruptions to the way universities operate. Online learning abruptly took priority, as the physical campuses in Australian universities became deserted. Staff had to instantly adapt to major changes in work practices, whilst continuing to support students’ engagement and maintain quality teaching and learning. This article discusses how change fatigue during the pandemic impacted the wellbeing of staff working in the enabling education sector. As staff and student wellbeing is interdependent, gaining a better understanding of the influences on staff wellbeing in the post-pandemic era is worth exploring in the context of discussions around student wellbeing …

Drawing About Writing: Exploring Egyptian Middle School Students’ Writing Motivation And Perceptions, Maryam Elbayady

Theses and Dissertations

The principal aim of this study is to explore Egyptian middle school students’ perceptions of their writing experiences using artistic expression, specifically drawings. It also aims to understand their levels of writing motivation using the Self-Beliefs, Writing-Beliefs, and Attitude Survey (SWAS) (Wright et al., 2019). Finally, it examines the relationships among participants’ perceptions, motivation, and their narrative writing performance. The view that students’ voices are valuable to research geared towards school improvement has largely propelled this study (Bland, 2018; Zumbrunn et al., 2017). In addition, due to the limited literature about middle school students enrolled at private Egyptian schools, this …

Exploring Policies & Practices For The Private Sector To Advance Women’S Economic Empowerment And Prevent Gender Based Violence In Post-Conflict Countries, Amina Helal

Theses and Dissertations

This study aims to investigate the role of the private sector in advancing women’s economic empowerment and gender-based violence prevention with a focus on post-conflict countries. It explores challenges facing them, and opportunities to be seized by governments and other stakeholders in this regard. The study also sheds light on the gap in the private sector’s awareness and commitment to achieve the UN Sustainable Development Goals (SDGs) and to implement the UN Women, Peace and Security (WPS) agenda in post-conflict countries. It explores the different possible engagements of the private sector in response to the research question. The thesis also …

Public Mental Health Through Social Media In The Post Covid-19 Era, Deepika Sharma, Jaiteg Singh, Babar Shah, Farman Ali, Ahmad Ali Alzubi, Mallak Ahmad Alzubi

All Works

Social media is a powerful communication tool and a reflection of our digital environment. Social media acted as an augmenter and influencer during and after COVID-19. Many of the people sharing social media posts were not actually aware of their mental health status. This situation warrants to automate the detection of mental disorders. This paper presents a methodology for the detection of mental disorders using micro facial expressions. Micro-expressions are momentary, involuntary facial expressions that can be indicative of deeper feelings and mental states. Nevertheless, manually detecting and interpreting micro-expressions can be rather challenging. A deep learning HybridMicroNet model, based …

Bringing Car T Cell Therapy Trials To Underserved Populations, Hoda Badr, Rayne Rouce, Michael E Scheurer, Premal Lulla, Martha Mims, Pavan Reddy

Faculty, Staff and Students Publications

There is a critical need for equitable access to cell therapies in cancer treatment, particularly within public safety-net healthcare systems that serve minority and socioeconomically disadvantaged populations. We discuss how the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine is piloting a cell therapy program aimed at addressing cancer care disparities and has the potential to serve as a national model for enhancing health equity in cancer care.

Dangerous John, J.W.M. Morgan

Valparaiso Fiction Review

No abstract provided.

Which Internet Content Is Often Used And Influenced Behavior? A Phenomenology About Students In Senior High School, Aris Martina, Siti Irene Astuti Dwiningrum, Heri Retnawati, Caly Setiawan

Informasi

At present, most students in the world, as well as Indonesia, especially senior high school students, have used the Internet for various purposes. Internet content presented on different platforms can now be accessed easily. Consciously or not, this media content influences their behavior. There is a lot of freely submitted content, which is worth knowing the impact. The question related to this study is which internet content is often used and affects high school students’ behavior. Qualitative methods with phenomenology have informants from the western, central, and eastern parts of Indonesia. Data were collected using observation, Google Forms, and interviews …

The Second Week Of Advent: A Nativity Village, Ann Zlotnik

Marian Library Blog Archive

Learn about St. Francis’ contribution to a Christmas tradition while traveling through a treasured Fontanini Nativity set.

Breaking Down Barriers To Aid: A 16 Days Of Activism Q&A With Chi-Chi Undie, Population Council

Sexual and Reproductive Health, Rights, and Choices

No abstract provided.

Mirror Therapy Rehabilitation In Low Back Pain Patients, Claudia L. Altergott

Honors Capstones

Low back pain is a common occurrence experienced by many individuals. An estimated 75-85% of Americans experience some form of back pain during their lives [1]. While low back pain can be uncomfortable and debilitating, approximately 90% of cases are temporary and can resolved without surgery; however, 50% of patients will experience recurrent episodes of back pain. Low back pain that has persisted for more than twelve weeks is considered chronic low back pain [1]. Many researchers and therapists have been seeking the optimal treatment plans for individuals suffering from low back pain. Mirror therapy (MT) is a type of …

Ddx170.1 Principles Of Design: Motif Example 2, Sae University College

Exemplars

DDX170 Project 1 Motif

Predicting Cost Contingency In Retrofit Projects Using Machine Learning Techniques, Dana Amin

Theses

Project contingency is one of the most important preliminary processes in any project estimation as it ensures the project risk for cost over-run due to uncertainties , in light of that, it is also important to make sure that the project contingency is not overestimated to maintain competitiveness in the market. This project aims to develop contingency decision support tool using ML techniques in order to predict the optimum contingency cost that balances between maintaining business competitiveness in the market and achieving project objectives. Different ML ways were evaluated and based on accuracy level ; Random Forest was found to …

Embracing Digital Mindsets To Ensure A Sustainable Future, Chengjun Li, Riqing Yu, Wenjing Ning, Huan Zhong, Christian Sonne

Biology Faculty Publications and Presentations

The 19th Asian Games astounded global audiences with an opening spectacle that showcased stunning digital fireworks (International Olympic Committee, 2021; Zhe, 2023). The groundbreaking display was brought to life through virtual reality (VR) and augmented reality (AR) technologies. It sets a pioneering example to replace conventional fireworks in major international events as well as in other large-scale entertainment activities, marking a historic milestone in the pursuit of a sustainable and healthy future.

The Second Week Of Advent: A Nativity Village, Ann Zlotnik

Marian Library Blog Archive

Learn about St. Francis' contribution to a Christmas tradition while traveling through a treasured Fontanini Nativity set.

The First Report Of Using Low-Field Mri-Guided Radiation Therapy In A Patient With A Cochlear Implant, James Mcculloch, Nema Bassiri Gharb, Alonso Gutierrez, Jennifer Armas, Kevin Abrams, Minesh Mehta, Michael Chuong, Kathryn Mittauer

All Publications

No abstract provided.

Could Ernest Boyer’S Foundational Perspective Of The Scholarship Of Teaching Help Save Faculty Librarians?, Douglas Wayman

The Christian Librarian

This is a recovery project for Ernest Boyer's scholarship of teaching as presented in Scholarship Reconsidered. It addresses a reinterpretation of Boyer’s scholarship of teaching promulgated by his Carnegie successor, Lee Shulman and popularized throughout the Academy. Serendipitously, that reinterpretation gave birth to what is now known as the Scholarship of Teaching and Learning (SoTL), which has undoubtedly benefitted the Academy. While this project focuses on the reinterpretation's ramifications for tenure-track academic library faculty who teach, it also argues that the foundational interpretation of Boyer's model could benefit the Academy at large, and that the two interpretations are not mutually …