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Characterisation Of Sex Chromosome Aneuploidy In Female Cattle Using Genotype Information, Cliona Ryan

ORBioM (Open Research BioSciences Meeting)

Background

Aneuploidy is a genetic condition characterized by the loss (monosomy) or gain (trisomy) of one or more chromosomes. Aneuploidy affecting the sex chromosomes often leads to infertility. The objective of this study was to estimate the prevalence of sex chromosome aneuploidy in a large juvenile population using routinely available genotype intensity information.

Methods

Genotype and genotype intensity data was available on 145,476 female dairy and beef cattle below 15 months of age at the time of genotyping, with no recorded progeny. Genotype intensity data included the LogR Ratio (LRR), R-value (the sum of X and Y SNP probe intensities), …

Impact Of Breeding For Dairy Traits On Beef Production, Shauna Mulhall

ORBioM (Open Research BioSciences Meeting)

Background

In recent years, there has been a large expansion in the dairy herd, accompanied by a reduction in the beef herd. Consequently, there has been a growing proportion of beef originating from the dairy herd. This study aims to investigate the impact of the current dairy cow breeding program on beef merit.

Methods

Following data edits, this study analysed 53,358 records of cow live weights and body condition scores, as well as slaughter records for 58,151 cows and 156,522 prime animals. Covariance components were estimated between various cow traits (BCS, live weight, carcass weight, conformation and fat score). Additionally, …

Grass-Based Supplementation To Reduce Slaughter Age In Dairy-Beef Steers, Jamie O'Driscoll

ORBioM (Open Research BioSciences Meeting)

Background

Reducing slaughter age, while maintaining carcass output, will improve the sustainability of beef production systems. This will result in lower lifetime emissions from cattle, while also reducing the carbon equivalent per kilogram of beef carcass. The objective of this study was to investigate the strategic use of concentrate feed within pasture-based dairy-beef steer production systems, to establish its effectiveness in reducing slaughter age in differing animal genotypes.

Methods

Three contrasting supplementation strategies were implemented: 1) grass only (GO), pasture only diet in the first and second grazing season, 2) intermediate (INTER), concentrate supplementation throughout the first grazing season, pasture …

The Detection Of Putative Recessive Lethal Haplotypes In Irish Sheep Populations, Rory Mcauley

ORBioM (Open Research BioSciences Meeting)

In livestock populations, recessive lethal alleles are a known contributor to poor reproductive performance due to embryonic death in homozygous individuals. Despite their lethal effect in the recessive form, these alleles may be maintained at high frequencies among carrier animals because of their positive pleiotropic effects on economically important traits. Although several such recessive alleles have been identified in cattle and pig populations, limited studies have been completed in sheep, and none within Irish sheep populations. Genotype data for 69,034 animals from five major Irish sheep breeds genotyped on a variety of panels was available for this study. Only animals …

Genetic Evaluation Of Enteric Methane For Sustainable Irish Beef Cattle, Clodagh Ryan

ORBioM (Open Research BioSciences Meeting)

Background:

Globally, livestock agriculture significantly contributes to human-induced greenhouse gas emissions, particularly through methane production. A potential approach to effectively, durably, and progressively reduce enteric methane emissions at a reasonable cost is through animal breeding.

Methods:

Individual animal methane records were available from 1,508 multi-breed growing beef cattle using GreenFeed Emission Monitoring systems. The objective of this study was to derive genetic parameters for a series of definitions of enteric methane, carbon dioxide, and dry matter intake (DMI). Estimated breeding values (EBVs) were generated for nine alternative definitions of enteric methane and EBVs were validated against phenotypic performance (adjusted for …

Npd1 + Rvd1 Combinatorial Treatment Improves Neurobehavioral Outcomes By Promoting The Expression Of Homeostatic Genes After Ischemic Stroke, Jeff Ji

Dr. Joseph M. Moerschbaecher, III Graduate Research Day

No abstract provided.

Assessment Of Frontal Cortex Function And Adolescent Alcohol’S Effect On Attentional And Response Inhibition Tasks, Hernan Mejia-Gomez

Dr. Joseph M. Moerschbaecher, III Graduate Research Day

No abstract provided.

The Hepatic Piston In Crocodilians: Functionally Validating Osteological Correlates And Identifying Its Origin In The Fossil Record, Andy Grand Pre

Dr. Joseph M. Moerschbaecher, III Graduate Research Day

No abstract provided.

Social Tourism Entrepreneurship As Tool For Development Of Rural Areas: A Case Study Of Himalayan Region Of Jammu & Kashmir, India, Basith Nabi Wani, Dr. Danish Iqbal Rania

Journal of Tourism Insights

The promotion of rural tourism has been suggested as a way to promote local economic, social, and cultural renewal. The importance of entrepreneurship in the tourism sector is growing. Since entrepreneurs may be vital in the growth of rural communities, especially those in less industrialized regions, they are frequently confronted with a variety of social issues. Finding new sources of revenue and employment possibilities for them is essential. There is no doubt that entrepreneurial businesses help the host community and the nation's economy. Kashmir's rural areas have certain unique characteristics that can be turned into enticing tourist destinations. This study …

Issue 430: November 2-16, 2023, The Local Voice

The Local Voice

No abstract provided.

Spartan Daily, November 2, 2023, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2023

Volume 161, Issue 32

International Companion Animal Welfare Conference (Icawc) 2023, Andrew Rowan, Kathleen Rowan

Tales of WellBeing

The ICAWC has evolved into a global forum featuring and sharing ideas and best practices on animal care and rescue.

"Animal Rights Law", Andrew Rowan

Tales of WellBeing

This volume by Raffael Fasel and Sean Butler is the first comprehensive text supporting a course on animal rights law.

From Horse-Drawn To Electric Carriages: Promoting A Paradigm Change, Janet White

Tales of WellBeing

Horses largely disappeared from urban streets in America after the 1920s. The development of a new e-carriage allows the few remaining horses to take a deserved retirement from dangerous, polluted urban streets.

Kenyon Collegian - November 2, 2023

The Kenyon Collegian

No abstract provided.

Maine's Right To Food: A Symbolic Right Or A Practical Right?, Tess Bedingfield

Cardozo Journal of Equal Rights and Social Justice (ERSJ) Blog

In November 2021, Maine became the first U.S. state to adopt a constitutional amendment guaranteeing the right to food. The amendment passed by a wide, bipartisan margin of 61% to 31% and states that "[a]ll individuals have a natural, inherent and unalienable right to food, including the right to save and exchange seeds and the right to grow, raise, harvest, produce and consume the food of their own choosing." Although many states have protected constitutional rights to hunt, fish, and farm, Maine’s constitutional amendment is the first to adopt such broad language enshrining food as an unalienable right. Prior to …

Comparison Of Dna Extraction Methods For The Detection Of Canned Tuna Species With Dna Mini-Barcoding, Aubrey J. Emmi, Biola Fatusin, Rosalee S. Hellberg

Food Science Faculty Articles and Research

Tuna is susceptible to species mislabeling due to its high demand, quick rate of production, and wide range of price points. DNA barcoding, a sequencing-based technique, allows for the detection of species mislabeling by targeting a standardized region of DNA. A mitochondrial control region (CR) DNA barcode has been found to be capable of species discrimination for tuna, but it is challenging to recover the entire DNA fragment from canned tuna. While a short fragment of CR, referred to as a “mini-barcode,” has shown some success with canned tuna species identification, more research is needed to improve identification rates. The …

Targeting Translation And The Cell Cycle Inversely Affects Ctc Metabolism But Not Metastasis, Tetiana Y. Bowley, Seth D. Merkley, Irina V. Lagutina, Mireya C. Ortiz, Margaret Lee, Bernard Tawfik, Dario Marchetti

Pathology Research and Scholarship

Melanoma brain metastasis (MBM) is significantly associated with poor prognosis and is diagnosed in 80% of patients at autopsy. Circulating tumor cells (CTCs) are "seeds" of metastasis and the smallest functional units of cancer. Our multilevel approach has previously identified a CTC RPL/RPS gene signature directly linked to MBM onset. We hypothesized that targeting ribogenesis prevents MBM/metastasis in CTC-derived xenografts. We treated parallel cohorts of MBM mice with FDA-approved protein translation inhibitor omacetaxine with or without CDK4/CDK6 inhibitor palbociclib, and monitored metastatic development and cell proliferation. Necropsies and IVIS imaging showed decreased MBM/extracranial metastasis in drug-treated mice, and RNA-Seq on …

Oregon State Rank Assessment For Mottled Sculpin (Cottus Bairdii), Misty Nelson

Institute for Natural Resources Publications

Oregon state conservation status assessment for Mottled sculpin (Cottus bairdii) using NatureServe methodology, 2023.

Vista: November 2, 2023, University Of San Diego

USD Vista (1965-)

No abstract provided.

The Impact Of International Technology Education Standards On The Development Of A National Curriculum: A Case Study In Korea, Euisuk Sung, Yuhuyn Choi, Ji Suk Kim, Eunsang Lee, Yunjin Lim

Publications and Research

South Korea has mandated technology education as a general education subject since 1954. However, recent educational trends, such as the emergence of computer education; artificial intelligence; Science, Technology, Engineering, and Mathematics (STEM); and K-12 engineering education call for considerable change in Korean technology education. The authors translated and published Standards for Technological and Engineering Literacy (STEL) in Korean to introduce the new standards to Korean educators in response to these challenges. This case study will review the history of Korean technology education from its inception in the 1960s and discuss the potential impacts of STEL on the Korean technology education …

Using Machine Learning To Measure Changes In Immunity Due To Climate Change In The Fall Armyworm, Spodoptera Frugiperda, Nathaniel T. Haulk

LSU Master's Theses

Object detection is a recent development that allows for the detection of multiple objects in photographs. Numerous machine learning algorithms have been developed for object detection. Here we sought to determine which algorithm performed best when relating to an organism's health and immunological response. The fall armyworm (Spodoptera frugiperda) is a major agricultural pest causing millions of dollars in damage to farmlands across the globe. With their recent spread into Africa and Asia, the need for understanding how best to control population outbreaks via biocontrol has increased. While viruses are a major biocontrol agent for controlling insect pests, we …

Independent- Nov. 2, 2023, Leslie Lozada

The Independent (1988-present)

No abstract provided.

Unh Scientist Named 2023 Kavli Fellow, Sarah Schaier

UNH Today Archive

No abstract provided.

Implementation Of Equine Therapy Into Treatment Programming For Adolescents With Substance Use Disorders, Gabrielle Rayfield

Dissertations, Theses, and Projects

Substance use disorders affect all populations. Adolescents are at greater risk of a substance use disorder when abuse begins at a young age. Over 50% of individuals with mental health diagnoses developed a substance use disorder before the age of 14 (Nebhinani et. al., 2022). [BJA1] Due to the tremendous growth that takes place during adolescence, and the profound impact substance use can have on development, it is imperative to provide early intervention. There are several evidenced-based approaches available in the treatment of adolescent substance use. Equine therapy has growing empirical support and will be the focus of this project. …

The Cowl - V. 88 N. 22 - November 2, 2023

The Cowl

The Cowl - student newspaper of Providence College. Vol. 88 No. 22 - November 2, 2023. 20 pages.

Associations Between Rest-Activity Rhythms And Liver Function Tests: The Us National Health And Nutrition Examination Survey, 2011-2014, Chris Ho Ching Yeung, Cici Bauer, Qian Xiao

Faculty, Staff and Student Publications

Liver functions are regulated by the circadian rhythm; however, whether a weakened circadian rhythm is associated with impaired liver function is unclear. This study aims to investigate the association of characteristics of rest-activity rhythms with abnormal levels of biomarkers of liver function. Data were obtained from the National Health and Nutrition Examination Survey 2011-2014. Seven rest-activity rhythm parameters were derived from 24 h actigraphy data using the extended cosine model and non-parametric methods. Multiple logistic regression and multiple linear regression models were used to assess the associations between rest-activity rhythm parameters and alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase …

Potentiation Of Apoptosis In Drug-Resistant Mantle Cell Lymphoma Cells By Mcl-1 Inhibitor Involves Downregulation Of Inhibitor Of Apoptosis Proteins, Yijing Li, Heng-Huan Lee, Vivian Changying Jiang, Yuxuan Che, Joseph Mcintosh, Alexa Jordan, Jovanny Vargas, Tianci Zhang, Fangfang Yan, Margaret Elizabeth Simmons, Wei Wang, Lei Nie, Yixin Yao, Preetesh Jain, Michael Wang, Yang Liu

Faculty, Staff and Student Publications

Bruton's tyrosine kinase inhibitors (BTKi) and CAR T-cell therapy have demonstrated tremendous clinical benefits in mantle cell lymphoma (MCL) patients, but intrinsic or acquired resistance inevitably develops. In this study, we assessed the efficacy of the highly potent and selective MCL-1 inhibitor AZD5991 in various therapy-resistant MCL cell models. AZD5991 markedly induced apoptosis in these cells. In addition to liberating BAK from the antiapoptotic MCL-1/BAK complex for the subsequent apoptosis cascade, AZD5991 downregulated inhibitor of apoptosis proteins (IAPs) through a BAK-dependent mechanism to amplify the apoptotic signal. The combination of AZD5991 with venetoclax enhanced apoptosis and reduced mitochondrial oxygen consumption …

Montana Kaimin, November 2, 2023, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

November 2, 2023, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.