Digital Commons Network^™

Single-Shot, Ultrafast, Multi-Frame X-Ray Imaging Of Defect-Bearing Ablator Materials In Extreme Conditions, Daniel S. Hodge

Theses and Dissertations

Characterization of the dynamic behavior of defect-bearing ablator materials subjected to extreme conditions is essential in advancing fusion energy as an reliable and abundant energy source. By understanding how materials evolve spatially and temporally we can minimize hydrodynamic instabilities, which are major contributing factors to energy yield degradation in inertial confinement fusion (ICF) experiments. In this thesis we demonstrate the capabilities of an ultrafast x-ray imaging (UXI) detector, the Icarus V2, where we capture multiple frames of single void-bearing sample compressed by a high-intensity laser shockwave. Using the Matter in Extreme Conditions (MEC) instrument at the Linac Coherent Light Source …

Examining The Impact Of Covid-19 On The Education And Development Of American Students, Riley Fortin '25

Student Research

After the COVID-19 pandemic, the vast majority of American children have fallen behind on core subjects due to the ultimate ineffectiveness of remote learning. This study attempts to discover the degree to which children have fallen behind through the trends in the National Association of Educational Procurement’s two most recent testing years. A database accessed from Google has been analyzed, filtered by state and visualized in tables in order to indicate any possible trends as a result of remote learning brought on by the pandemic. By looking at data in seven different states across the country, there is a notable …

Unh, Northeast Passage Earn Team Usa Collegiate Impact Honor, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Mitigating Coastal Erosion For Great Bay, Autumn Bedell

UNH Today Archive

No abstract provided.

F-Box Receptor Mediated Control Of Substrate Stability And Subcellular Location Organizes Cellular Development Of Aspergillus Nidulans, Bayram Ö Sarikaya, Ö Bayram, B Karahoda, C Meister, Am Köhler, S Thieme, N Elramli, D Frawley, J Mcgowan, Da Fitzpatrick, K Schmitt, Leandro Jose De Assis, O Valerius, Gh Goldman, Gh Braus

Peninsula Medical School

Fungal growth and development are coordinated with specific secondary metabolism. This coordination requires 8 of 74 F-box proteins of the filamentous fungus Aspergillus nidulans. F-box proteins recognize primed substrates for ubiquitination by Skp1-Cul1-Fbx (SCF) E3 ubiquitin RING ligases and degradation by the 26S proteasome. 24 F-box proteins are found in the nuclear fraction as part of SCFs during vegetative growth. 43 F-box proteins interact with SCF proteins during growth, development or stress. 45 F-box proteins are associated with more than 700 proteins that have mainly regulatory roles. This corroborates that accurate surveillance of protein stability is prerequisite for organizing multicellular …

The Geriatric Emergency Department At The University Of California San Francisco: Structures, Roles, And Lessons Learned, Todd James

Journal of Geriatric Emergency Medicine

No abstract provided.

The Effects Of A Hardiness Educational Intervention On Hardiness And Perceived Stress Of Baccalaureate Nursing Students, Paula R. Jameson

Dissertations

Despite the known benefits of hardiness education, no published research has been found on the effects of hardiness education with nursing students. Thus, the purposes of this study were first to determine if an increase in hardiness and a decrease in perceived stress in baccalaureate nursing students occurred in those who participated in a hardiness educational intervention. Secondly, to compare hardiness and perceived stress between baccalaureate nursing students who participated and those who did not participate in a hardiness educational intervention. A substruction of the application of Khoshaba and Maddi's Hardiness Model and the Roy Adaptation Model provided the theoretical …

Creating An Instrument To Explore The Self-Efficacy Of Writing Instructors To Teach Apprehensive Writers, Kathleen Marie Romrell

Theses and Dissertations

Writing apprehension is a writing difficulty that can impair the writing experiences of students. While researchers have proposed many interventions that teachers can implement to assist their students who struggle with writing apprehension, there has not been an instrument that is designed to measure teacher self-efficacy to help these same students. This study created such an instrument, entitled the Self-efficacy to Teach Apprehensive Writers Scale (STAWS), using Tschannen-Moran and Woolfolk Hoy’s (2001) Teacher Sense of Efficacy Scale and Daly and Miller’s (1975) Writing Apprehension Test as model instruments. The new instrument was designed to measure writing instructor self-efficacy to teach …

Delivering Explicit Math Instruction Through Point-Of-View Video Modeling To Elementary Students With Autism Spectrum Disorder, Patsy Mccray Gibbs

Theses and Dissertations

There is significant literature demonstrating the effectiveness of video modeling for teaching skills to students with disabilities. Still, much less is known about how video modeling, particularly point-of-view video modeling (POV-VM), might be applied to teach academic skills to children with an autism spectrum disorder. This multiple probe single-case design study used explicit instruction techniques to teach multiplication, division, and fraction skills to two elementary-aged students with an autism spectrum disorder. A visual analysis of the data showed that POV-VM using explicit techniques to deliver the videos is an effective intervention for autistic students This research study adds to the …

Sociology Between The Gaps Volume 7 (2022)

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.

Co-Management Strategies For Acute Myeloid Leukemia Patients In The Community Setting, Christopher Benton, Michael R Grunwald, Hana Safah, Margaret Kasner

Department of Medical Oncology Faculty Papers

The treatment landscape for acute myeloid leukemia (AML) has changed substantially in recent years. The introduction of newer therapies, including oral agents, less myelosuppressive agents, and parenteral regimens suitable for outpatient administration, has made it feasible for select patients to receive therapy in the outpatient setting and in community practices. Thorough patient evaluation (including molecular testing), planned supportive care (eg, transfusion support, antimicrobial prophylaxis), and vigilant patient monitoring (for tumor lysis syndrome and adverse events) by a multidisciplinary team are required for successful management of patients both in the community and at specialized leukemia centers. Some patients are unable or …

The Presynaptic Role Of Phosphagen Systems, Carlos David Oliva

Harriet L Wilkes Honors College Theses

De novo generation of ATP through glycolysis and oxidative phosphorylation is too slow to sustain intense neuronal activity and stabilize ATP levels, suggesting there might be another energy pool at play. The phosphagen system, extensively researched in muscles, is an ATP regeneration pathway; quickly producing ATP through ADP re-phosphorylation. Its presence has been observed in neurons, yet its involvement in neuronal power demands remains poorly understood. To investigate the phosphagen system’s impact on neuronal energy metabolism, we examined Drosophila melanogaster motor neurons, which had arginine kinase knocked down while using genetically-encoded fluorescent reporters of pH, calcium, and ATP. Data obtained …

Tyler Ninalga Junior Piano Recital, Andrews University

Student Degree Recitals 2022-2023

Tyler Ninalga - Pianist

A Phenomenological Study Of Collegiate Recovery Leadership, Marni Goldberg

Teacher Education, Educational Leadership & Policy ETDs

Due to the marginalized status of the population they serve, collegiate recovery programs are generally underfunded and employ one staff member who typically holds other job tasks in addition to those of collegiate recovery leader. The consequence of the varied nature by which collegiate recovery programs are founded and implemented is inconsistency, which can threaten the longevity of the field. The purpose of this phenomenological study was to elicit information directly from collegiate recovery leaders to gain a deeper understanding of their lived experience, in order to determine how to best serve and support higher education students in recovery from …

December 12, 2022 - Passed - Resolution To Endorse The Project Report Conceptualizing Teaching Excellence At Ohio University, Ohio University Faculty Senate

Faculty Senate Resolutions

No abstract provided.

Amber Kujath '97 To Lead Illinois Wesleyan School Of Nursing, Illinois Wesleyan University

News and Events (Discontinued Series)

No abstract provided.

Preventative Healthcare Programs, Caileb T. Reilly

Honors Thesis

The healthcare system in the United States is struggling with excessive costs and disproportionate quality measures. While the U.S. spends the most on healthcare in the world, the quality of the healthcare is not reflected in this cost. With excessive spending being the strategy to improve quality in the past, new strategies need to be implemented to improve quality as increased spending is not raising this statistic. One factor that can improve quality and reduce costs is the introduction and utilization of preventative healthcare programs. These programs are built to keep at-risk populations from developing serious, permanent diseases that deplete …

Gabapentin Disrupts Binding Of Perlecan To The Α 2Δ1 Voltage Sensitive Calcium Channel Subunit And Impairs Skeletal Mechanosensation, Perla C Reyes Fernandez, Christian S Wright, Adrianna N Masterson, Xin Yi, Tristen V Tellman, Andrei Bonteanu, Katie Rust, Megan L Noonan, Kenneth E White, Karl J Lewis, Uma Sankar, Julia M Hum, Gregory Bix, Danielle Wu, Alexander G Robling, Rajesh Sardar, Mary C Farach-Carson, William R Thompson

Faculty, Staff and Student Publications

Our understanding of how osteocytes, the principal mechanosensors within bone, sense and perceive force remains unclear. Previous work identified "tethering elements" (TEs) spanning the pericellular space of osteocytes and transmitting mechanical information into biochemical signals. While we identified the heparan sulfate proteoglycan perlecan (PLN) as a component of these TEs, PLN must attach to the cell surface to induce biochemical responses. As voltage-sensitive calcium channels (VSCCs) are critical for bone mechanotransduction, we hypothesized that PLN binds the extracellular α2δ1 subunit of VSCCs to couple the bone matrix to the osteocyte membrane. Here, we showed co-localization of PLN and α2δ1 along …

Mapping Single-Cell Transcriptomes In The Intra-Tumoral And Associated Territories Of Kidney Cancer, Ruoyan Li, John R Ferdinand, Kevin W Loudon, Georgina S Bowyer, Sean Laidlaw, Francesc Muyas, Lira Mamanova, Joana B Neves, Liam Bolt, Eirini S Fasouli, Andrew R J Lawson, Matthew D Young, Yvette Hooks, Thomas R W Oliver, Timothy M Butler, James N Armitage, Tev Aho, Antony C P Riddick, Vincent Gnanapragasam, Sarah J Welsh, Kerstin B Meyer, Anne Y Warren, Maxine G B Tran, Grant D Stewart, Isidro Cortés-Ciriano, Sam Behjati, Menna R Clatworthy, Peter J Campbell, Sarah A Teichmann, Thomas J Mitchell

Faculty, Staff and Student Publications

Tumor behavior is intricately dependent on the oncogenic properties of cancer cells and their multi-cellular interactions. To understand these dependencies within the wider microenvironment, we studied over 270,000 single-cell transcriptomes and 100 microdissected whole exomes from 12 patients with kidney tumors, prior to validation using spatial transcriptomics. Tissues were sampled from multiple regions of the tumor core, the tumor-normal interface, normal surrounding tissues, and peripheral blood. We find that the tissue-type location of CD8+ T cell clonotypes largely defines their exhaustion state with intra-tumoral spatial heterogeneity that is not well explained by somatic heterogeneity. De novo mutation calling from single-cell …

Gambaran Faktor Kegagalan Laten Dan Kegagalan Aktif Pada Kecelakaan Transportasi Darat Di Indonesia Tahun 2019 – 2021, Rahma Laili Khairina, Dadan Erwandi

National Journal of Occupational Health and Safety

Road transportation accidents are the eighth leading cause of death worldwide, reaching 1.35 million people annually (WHO, 2021). Data from the NTMC Korlantas Polri for 2019-2021 shows that the number of road transportation accidents in Indonesia is above 100 thousand every year. This study identifies latent and active failure factors contributing to Indonesia's land transportation accidents to determine the causes of accidents comprehensively. This study uses secondary data with 320,084 traffic accident case reports in 2019-2021 belonging to the NTMC Korlantas Polri. The method used is qualitative by analyzing based on the Swiss Cheese Model. The results of this study …

Analisis Faktor Yang Berhubungan Dengan Fatigue Pada Pegawai Dinas Kesehatan Provinsi Dki Jakarta Tahun 2022, Halimatuzzahra Halimatuzzahra, Dadan Erwandi

National Journal of Occupational Health and Safety

In 2020 cases of Covid-19 were found in various parts of the world, one of which was in Indonesia. Since it was first discovered, this case has continued to increase, with DKI Jakarta Province being the highest contributor to daily positive cases of Covid-19 in Indonesia. The Indonesian government continues to make efforts and cooperation between institutions. One of the institutions it has is the Health Agency. However, the arrangements and working conditions that have changed following the development of the Covid-19 case can cause fatigue for employees of the DKI Jakarta Health Agency.. This study aims to analyze the …

Decision-Based Learning As A Tool For Teaching Statistics In A Peruvian University, Gloria Mora Barba

Theses and Dissertations

Many students find that learning statistics is difficult, especially novice learners first taking statistical classes. Instructors also struggle to teach statistics due to many challenges, such as students' misconceptions, lack of math skills, negative attitudes, and deficient instructional methods. A new pedagogical approach called Decision-Based Learning (DBL) has been developed to help instructors and students overcome these challenges. A group of Peruvian university professors in 2018 and 2019 were trained to use DBL. However, limited studies have explored DBL instructors' and students' experiences using DBL in Peru. The aim of this qualitative research study is to deeply understand the experiences …

Outdoor Recreation And Its Effect On Our Relationship With The Environment, Martin Brannaman

Department of Environmental Studies: Undergraduate Student Theses

This study was conducted at the University of Nebraska Outdoor Adventure Center. This study employed a pre-post retrospective assessment looking at individuals' connection with nature after embarking on a direct outdoor experience. A direct outdoor experience is when an individual is outside and not surrounded by manmade structures (Kil, 2016). I believe that after a direct outdoor experience the sample group will have a significant change in their connection to nature. The objective is to measure change in a group's connection to nature, through the Connectedness to Nature Scale (CNS, Mayer & Frantz, 2004). The population was a group of …

Eastern Redcedar Reduces Regeneration And Diversity In The Forests Of The Niobrara River Valley, Abigail Ridder

Department of Environmental Studies: Undergraduate Student Theses

Boundary forests are found growing interdigitated with grasslands across the Great Plains. The Niobrara River valley boundary forest has a unique composition of species not seen anywhere else in North America. Encroachment of eastern redcedar (Juniperus virginiana L.) into grasslands and forests is significantly increasing eastern redcedar’s presence in the Niobrara River Valley as well as in the rest of the Great Plains region. This tree species is capable of significantly decreasing recruitment and diversity in grasslands, which can change the composition of the entire ecosystem. However, the effect of eastern redcedar on recruitment and diversity of naturally forested ecosystems …

Teachers’ Perception Of The Impact Of The Switch To Emergency Remote Teaching On Students With Disabilities During The Covid-19 Pandemic, Chinwe Osondu

Seton Hall University Dissertations and Theses (ETDs)

Abstract

The purpose of this qualitative study is to explore teachers’ perception of the impact of the switch to emergency remote teaching on students with disabilities during the coronavirus disease 2019 (COVID-19) pandemic, as well as the factors that helped or hindered their academic and social-emotional achievement levels and motivation. A secondary goal of this study is to add to the literature on strategies to improve the outcomes of students with disabilities in an online/virtual learning environment. An interview protocol that included semi-structured, open-ended questions was used to capture the perceptions of 15 special education teachers. Rich qualitative data were …

Teaching Autistic Children To Independently Wash Their Hands: A Systematic Review Of Behavioral Techniques, Alexis Vazquez

Seton Hall University Dissertations and Theses (ETDs)

With COVID 19 having changed the world’s perception on daily hygiene, people are aiming to improve the rate and efficacy of their hand washing. Autistic children, having a history of challenges with daily living skills, may need support when learning the skill of hand washing. The current review discusses interventions used to teach autistic children effective hand washing and investigates if those interventions meet criteria to be considered an evidence-based practice. Six studies met the inclusion criteria and data were synthesized narratively. Given the importance of hand washing in society, more research is necessary to achieve optimal outcomes. The review …

Understanding The Experiences Of African American Caregivers Of Loved Ones With Dementia, Paula R. Madison

Seton Hall University Dissertations and Theses (ETDs)

Background: Dementia is a public health problem that is estimated to triple by 2050.Globally, dementia is the seventh leading cause of death among all diseases and one of the major causes of disability and dependency among older people. The direct medical costs and indirect social and economic costs of dementia are burdensome to society, and by 2030 it is projected to cost more than $2.8 TRILLION dollars worldwide. African Americans are two to four times more likely to be diagnosed with dementia than White Americans; and more likely to rely on informal care from family and friends. African …

The Relationship Between Parcc Ela 8 Performance And Performance On Ap Exams, Michael G. Portas

Seton Hall University Dissertations and Theses (ETDs)

This quantitative study is primarily intended to examine whether district level performance results from Grade 8 ELA state assessments can help to predict future passing rates on AP exams. The participants for the study are all 218 K-12 school districts in New Jersey, all of which generated results across score levels and passing rates for PARCC testing in the academic years ending in 2015-2017. District level data were also examined for possible predictive validity on AP passing rates in 2019-2021 across categories including demographics, college entrance exams taken in high school, and participation rates in AP/IB coursework and exams, most …

Bis-Indolyl Compounds And The Induction Of Apoptosis In T98g Glioblastoma Multiforme Cells, Margot C. Brown

Seton Hall University Dissertations and Theses (ETDs)

1,1-bis(3’idolyl)-1(aryl)methane compounds (BIM compounds) have been shown to have anti-cancer properties in colon cancer, bladder cancer, and leukemia cells. The purpose of this work was to determine if BIM compounds could be an effective treatment of glioblastoma multiforme. Sulforhodamine B (SRB) assays showed that 20µM of the BIM compounds could inhibit cellular proliferation of the T98G glioblastoma multiforme cell line over 72 hours. Then immunoblotting was used to analyze the molecular pathway induced by BIM compounds. An increase in the expression of both BAX and cleaved caspase 3 suggest BIM compounds activate programmed cell death, or apoptosis in glioblastoma cells. …

Ohio University Faculty Senate Agenda December 12, 2022, Ohio University Faculty Senate

Faculty Senate Agendas

No abstract provided.