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Development Of Functional Markers For Resistance To Smut And Identification Of Genes Differentially Expressed In Response To Brown Rust In Sugarcane, Jose David Cortes

LSU Doctoral Dissertations

Smut, caused by Sporisorium scitamineum and brown rust, caused by Puccinia melanocephala, are two of the most important diseases that affect sugarcane production in Louisiana and worldwide. Smut continues to cause losses in the breeding program in Louisiana. Therefore, a QTL analysis was conducted to identify molecular markers associated with resistance in F₁ progeny (162) of a biparental cross between susceptible cultivar L 99-233 and resistant HoCP 96-540. Using 1,574 single-dose SNP markers, a total of 253 linkage groups (LG) were obtained with a genome coverage of 24,580.15 cM. Six QTLs were localized on five LGs. The highest …

An Investigation Of Neuronal Cytosolic Ph And Mitochondrial Energy Metabolism In Mdh2 Drosophila Mutants, Frank Andrew Sigui

Harriet L Wilkes Honors College Theses

Mitochondria are vital organelles essential for proper function of the human body. Mutations in genes encoding mitochondrial proteins lead to mitochondrial dysfunction and severe neurological symptoms. Children reported to have mutations within the gene encoding the enzyme, mitochondrial malate dehydrogenase (MDH2) exhibit symptoms of hypotonia, lactic acidosis and epilepsy. No treatment exists for this disorder and the neurological symptoms stemming from MDH2 mutations require further investigation. Decrease in pH, associated with an increase in lactate production, may contribute to symptoms experienced by children with MDH2 mutations. To investigate pH in individuals with MDH2 mutations, we used CRISPR/Cas9 techniques to introduce …

Evaluation Of Simvastatin As A Disease-Modifying Treatment For Patients With Parkinson Disease: A Randomized Clinical Trial, Kara N. Stevens, Siobhan Creanor, Alison Jeffery, Alan Whone, John Zajicek, Andy Foggo, Ben Jones, Rebecca Chapman, Laura Cocking, Jonny Wilks, Doug Webb, Camille Carroll

Peninsula Medical School

Importance: Current treatments manage symptoms of Parkinson disease (PD), but no known treatment slows disease progression. Preclinical and epidemiological studies support the potential use of statins as disease-modifying therapy. Objective: To determine whether simvastatin has potential as a disease-modifying treatment for patients with moderate PD. Design, Setting, and Participants: This randomized clinical trial, a double-blind, parallel-group, placebo-controlled futility trial, was conducted between March 2016 and May 2020 within 23 National Health Service Trusts in England. Participants aged 40 to 90 years with a diagnosis of idiopathic PD, with a modified Hoehn and Yahr stage of 3.0 or less while taking …

Five Things You Should Know This Week, Georgia Southern University

A Few Things You Should Know This Week (2020-2023)

• Get Your Booster Shot Before the Break and Get $25!
• 2022 Employee Engagement Survey Launches Next Week
• Vaccine Shots and Boosters are Available on Campus
• Performance Evaluations Should be Underway
• COVID-19 Testing Available on Campus

Board Of Directors Meeting Minutes (December 12, 2022), Dmacc

Board of Directors Meeting Minutes

This file contains the minutes from the Des Moines Area Community College Board meeting held on December 12, 2022.

Explaining Suharto's Rise And Fall: International And Domestic Variables, Julia Batanghari

Undergraduate Honors Theses

For three decades (1968-1998), Indonesia was led by President Suharto, whose authoritarian military regime is remembered for its corruption and brutality. This paper offers an analysis of Suharto’s rule through the lens of two events: his 1965 purge of local ‘communists’ and the riots of May 1998. Drawing comparisons between the two, I delve into systemic causes by considering the influence of domestic and international variables. Exploring links between intergroup accommodation and democracy reveals that Suharto’s lack of ethnic, socioeconomic, and religious inclusivity paved the way not only for the anti-Chinese sentiment which pervaded Indonesian society during his presidency, but …

A Preliminary Assessment Of Compassion Fatigue In Chimpanzee Caregivers, Mary Lee A. Jensvold

Anthropology and Museum Studies Faculty Scholarship

Compassion fatigue is defined as “traumatization of helpers through their efforts at helping others”. It has negative effects on clinicians including reduced satisfaction with work, fatigue, irritability, dread of going to work, and lack of joy in life. It is correlated with patients’ decreased satisfaction with care. Compassion fatigue occurs in a variety of helping professions including educators, social workers, mental health clinicians, and it also appears in nonhuman animal care workers. This study surveyed caregivers of chimpanzees using the ProQOL-V to assess the prevalence of compassion fatigue among this group. Compassion satisfaction is higher than many other types of …

Department Of Environment And Conservation And Underground Storage Tanks And Solid Wase Disposal Control Board, December 2022, Tennessee. Comptroller Of The Treasury.

Performance Audit Reports

No abstract provided.

The Spectral Sensitivity Of Human Circadian Phase Resetting And Melatonin Suppression To Light Changes Dynamically With Light Duration, Melissa A. St Hilaire, María L. Ámundadóttir, Shadab A. Rahman, Shantha M. W. Rajaratnam, Melanie Rüger, George C. Brainard, Charles A. Czeisler, Marilyne Andersen, Joshua J. Gooley, Steven W. Lockley

Department of Neurology Faculty Papers

Human circadian, neuroendocrine, and neurobehavioral responses to light are mediated primarily by melanopsin-containing intrinsically-photosensitive retinal ganglion cells (ipRGCs) but they also receive input from visual photoreceptors. Relative photoreceptor contributions are irradiance- and duration-dependent but results for long-duration light exposures are limited. We constructed irradiance-response curves and action spectra for melatonin suppression and circadian resetting responses in participants exposed to 6.5-h monochromatic 420, 460, 480, 507, 555, or 620 nm light exposures initiated near the onset of nocturnal melatonin secretion. Melatonin suppression and phase resetting action spectra were best fit by a single-opsin template with lambda_max at 481 and 483 …

Efficacy And Safety Of Fecal Microbiota Transplantation In Treatment Of Clostridioides Difficile Infection Among Pediatric Patients: A Systematic Review And Meta-Analysis, Kyaw Min Tun, Mark Hsu, Kavita Batra, Chun-Han Lo, Tooba Laeeq, Tahne Vongsavath, Salman Mohammed, Annie S. Hong Md

Department of Internal Medicine Faculty Research

Background and Aims: Cases of Clostridioides difficile infection have been rising among the pediatric and adolescent population. Fecal microbiota transplantation (FMT) has emerged as an alternative therapy for recurrent C. difficile infection. We aim to perform the first systematic review and meta-analysis investigating the safety and efficacy of fecal microbiota transplantation for C. difficile infection in children and adolescents. Methods: A literature search was performed using variations of the keywords “pediatrics”, “C. difficile infection”, and “fecal microbiota transplantation” in PubMed, EMBASE, CINAHL, Cochrane, and Google Scholar from inception to 30 June 2022. The resulting 575 articles were independently screened by …

Divergent Post-Breeding Spatial Habitat Use Of Laysan And Black-Footed Albatross, Fredrick Dallas Jordan, Scott A. Shaffer, Melinda G. Conners, Julia E.F. Stepanuk, Morgan E. Gilmour, Corey A. Clatterbuck, Elliott L. Hazen, Daniel M. Palacios, Yann Tremblay, Michelle Antolos, David G. Foley, Steven J. Bograd, Daniel P. Costa, Lesley H. Thorne

Faculty Research, Scholarly, and Creative Activity

Understanding the at-sea movements of wide-ranging seabird species throughout their annual cycle is essential for their conservation and management. Habitat use and resource partitioning of Laysan (Phoebastria immutabilis) and black-footed (Phoebastria nigripes) albatross are well-described during the breeding period but are less understood during the post-breeding period, which represents ~40% of their annual cycle. Resource partitioning may be reduced during post-breeding, when birds are not constrained to return to the nest site regularly and can disperse to reduce competitive pressure. We assessed the degree of spatial segregation in the post-breeding distributions of Laysan (n = 82) and black-footed albatrosses (n …

20221212_Access Pediatrics & Access Surgery Added To Hslic's Collection, Robyn Gleasner

HSLIC Blog Post

No abstract provided.

Parental Warmth And Disciplinary Strategies In Two-Parent-Adoptive And Biological Families, Jordan Coburn

Theses and Dissertations

Adopted children enter families with parents who on average are older, have higher income, and have more education than other family structures. Because adopted children are moving into families with more resources, research suggests that they would do just as well as, and perhaps even better than, children in biological two-parent households. However, this is not always the case. Understanding how different variables could offset any negative results of adoption is a puzzle that researchers are continually exploring. Previous research has investigated differences in investments from adoptive and biological parents through multiple theoretical lenses. I seek to add to current …

Does Predation Environment Affect Repeated Responses To Predation Cuesâ In The Fishâ Brachyrhaphis Rhabdophora?, Madeleine S. Nate

Theses and Dissertations

Individual organisms face trade-offs when dealing with predation—more time spent avoiding predators often results in less time allocated to energy acquisition and reproductive-related activities. Individuals that optimize this trade-off and respond appropriately to current risk levels in their environment should be at an advantage. What is less clear is whether this tradeoff changes when individuals are repeatedly exposed to a predation threat. There may be advantages to responding consistently to every signal of threat, but it might also be advantageous to modulate individual behavior. Moreover, it is unclear how evolutionary history of a population might affect such individual responses. Our …

High School Dropouts, Higher Education Dreams, And Achievement: A Six-Year Study Of A High-Stakes Test In Brazil, Eveline Miranda

Theses and Dissertations

Rumberger (2020) observed that "dropping out of school has economic and social consequences both for dropouts themselves and for the country as a whole" (p. 151). Every year, many Brazilians drop out of school due to work, early pregnancies, marriage, drug consumption, crime, etc. Dropping out of school can occur due to learning challenges, poor attendance, discipline problems, or a lack of access to high school institutions. Dropouts can experience depression and anxiety and are more likely to attempt suicide. The present dissertation includes two different papers about dropouts. The first paper uses fixed effect regression to show the main …

Structural Reasoning With Rational Expressions, Dana Steinhorst

Theses and Dissertations

Many students struggle to make sense of algebraic expressions in math. This lack of understanding results in students making symbolic manipulation errors, hindering their procedural fluency. Researchers believe these errors are linked to students' lack of structural reasoning. While research has shown that students rarely engage in expert structural reasoning, little is known about how students actually reason structurally. In this study, I interviewed six high school calculus students to study the way they identified, matched, and evaluated structures as they solved problems involving rational expressions and equations. I analyzed the participant interviews and outlined the matching process they used …

Teaching Social-Emotional Learning To Children With Autism Using Animated Avatar Video Modeling, Emelie Davis

Theses and Dissertations

People with a diagnosis of autism spectrum disorder (ASD) often have difficulties understanding or applying skills related to Social-Emotional Learning (SEL). An individual having a better understanding of SEL concepts is generally associated with more fulfilling connections with others and increased satisfaction in life. Since people with ASD tend to have greater success with learning in structured environments, we created a module to teach these skills using Nearpod. These modules were created with videos of a person embodying a cartoon dog face using Animoji for two reasons; because the animation was meant to appeal to children, and the creation was …

Determination Of A Catalytic Mechanism By Time Resolved Fourier Transform Infrared Spectroscopy And Time Domain Analysis Of Data From Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, Jacob T. Davis

Theses and Dissertations

Heterobimetallic catalysts offer large potential for efficient and selective catalysis of a wide range of reactions. Better understanding of these catalytic mechanisms could yield further improvement in their catalytic abilities. Cp(CO)2Fe-Cu(IPr) (IPr = N,N-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) is a catalyst that has been reported to catalyze arene borylation. The catalytic mechanism of this catalyst that had been previously proposed had the initial step being a metal-metal cleavage. However, computational modeling suggested an alternate mechanism that could be more energetically favorable. Rather than a metal-metal cleavage as the initial step, we proposed a photoactivated carbonyl dissociation. To support this proposition, we performed time resolved …

Zeros Of A Family Of Complex-Valued Harmonic Rational Functions, Alexander Lee

Theses and Dissertations

The Fundamental Theorem of Algebra is a useful tool in determining the number of zeros of complex-valued polynomials and rational functions. It does not, however, apply to complex-valued harmonic polynomials and rational functions generally. In this thesis, we determine behaviors of the family of complex-valued harmonic functions $f_{c}(z) = z^{n} + \frac{c}{\overline{z}^{k}} - 1$ that defy intuition for analytic polynomials. We first determine the sum of the orders of zeros by using the harmonic analogue of Rouch\'e's Theorem. We then determine useful geometry of the critical curve and its image in order to count winding numbers by applying the harmonic …

Persain V. Persane

All Decisions

No abstract provided.

Ahmed V. Mohammed

All Decisions

No abstract provided.

Corzo V. David

All Decisions

No abstract provided.

Initial Data Generation And Dynamical Simulations Of Binary Neutron Star Systems, Tanmayee Gupte

Theses

The recent detection of gravitational waves (GWs) from a system of binary neutron stars (BNS) in coincidence with electromagnetic observations has launched a new era of multimessenger astrophysics. In light of the complementary knowledge to be gained through simultaneous observations, BNS mergers are one of the main targets for terrestrial GW interferometric detectors. These observations may prove critical in understanding the equation of state (EOS) of the nuclear matter inside the neutron star core, which is still poorly constrained given current observations. Understanding the neutron star (NS) EOS is critical for binary parameter estimation, and will hopefully aid in the …

The Pendulum Of Juvenile Justice Policy: Examining The Creation And Implementation Of New York State’S Raise The Age Legislation, Mary Xitco

Theses

This paper discusses changes in juvenile justice policy, focusing largely on the last 40 years. Juvenile justice policy has historically transitioned quickly from conservative punitive strategies to liberal rehabilitative and lenient strategies. We see this most recently with the tough on crime strategies of the 1990s lowering the age of responsibility to now where states have decided to start raising the age of criminal responsibility up to 18 years old. This paper looks closely at what caused this most recent shift and gives historical context as to how juvenile justice policy trends may have predicted this.

Issues In Melanoma Detection: Semisupervised Deep Learning Algorithm Development Via A Combination Of Human And Artificial Intelligence, Xinyuan Zhang, Ziqian Xie, Yang Xiang, Imran Baig, Mena Kozman, Carly Stender, Luca Giancardo, Cui Tao

Faculty, Staff and Student Publications

BACKGROUND: Automatic skin lesion recognition has shown to be effective in increasing access to reliable dermatology evaluation; however, most existing algorithms rely solely on images. Many diagnostic rules, including the 3-point checklist, are not considered by artificial intelligence algorithms, which comprise human knowledge and reflect the diagnosis process of human experts.

OBJECTIVE: In this paper, we aimed to develop a semisupervised model that can not only integrate the dermoscopic features and scoring rule from the 3-point checklist but also automate the feature-annotation process.

METHODS: We first trained the semisupervised model on a small, annotated data set with disease and dermoscopic …

A Framework For Multi-Dimensional Assessment Of The Impacts Of Overweight Vehicle Operations And A Corridor-Level Case Study, Maria Alicia Chung Li

Lyles School of Civil Engineering Graduate Student Reports

Ground freight transportation is essential for the economy of any region. The efficient movement of goods from one location to another connects businesses with suppliers and customers, that enhances commerce and ultimately boosts the economy. The high volume of freight that has been transported on the nation’s highway network has allowed the trucking industry to provide enormous socio-economic benefits. Unfortunately, these benefits come with some costs associated with the operation of overweight (OW) trucks, such as accelerated deterioration of highway pavement and bridge assets, and passenger and freight traffic safety degradation. Thus, to manage safety risk, traffic mobility, and infrastructure …

A New Gtseq Resource To Facilitate Multijurisdictional Research And Management Of Walleye Sander Vitreus, Peter T. Euclide, Wesley A. Larson, Matthew Bootsma, Loren M. Miller, Kim T. Scribner, Wendylee Stott, Chris C. Wilson, Emily K. Latch

Purdue University Libraries Open Access Publishing Fund

Conservation and management professionals often work across jurisdictional boundaries to identify broad ecological patterns. These collaborations help to protect populations whose distributions span political borders. One common limitation to multijurisdictional collaboration is consistency in data recording and reporting. This limitation can impact genetic research, which relies on data about specific markers in an organism's genome. Incomplete overlap of markers between separate studies can prevent direct comparisons of results. Standardized marker panels can reduce the impact of this issue and provide a common starting place for new research. Genotyping-in-thousands (GTSeq) is one approach used to create standardized marker panels for nonmodel …

Black Holes, Disk Structures, And Cosmological Implications In E-Dimensional Space, Subhash Kak, Menas C. Kafatos

Mathematics, Physics, and Computer Science Faculty Articles and Research

We examine a modern view of the universe that builds on achieved successes of quantum mechanics, general relativity, and information theory, bringing them together in integrated approach that is founded on the realization that space itself is e-dimensional. The global and local implications of noninteger dimensionality are examined, and how it may have increased from the value of zero to its current value is investigated. We find surprising aspects that tie to structures in the universe, black holes, and the role of observations.

Bob Reich Oral History Interview, Bob Reich, Mathew Lin

Raymond College

No abstract provided.

The Effect Of Climate Change On Firm Level Costs With Focus On Mena Region, Farah Osama Saieed

Theses and Dissertations

This paper has a main objective of identifying the relationship between environmental factors and climate change on operating costs incurred by firms. This paper also attempts to compare the direction and intensity of the effect on different sectors in order to analyze whether climate change effect differs based on the nature of the business operations. Several papers have previously addressed the relationship between climate change factors ad profits. This literature will add to previous studies by observing the effect on the cost rather than the profits. In addition to providing results that minimize endogeneity, which is found in a large …