Digital Commons Network^™

Abl2 Promotes Alcohol-Associated Liver Disease Via Ppar Gamma Regulation, Gregory Malnassy

Dissertations

Alcohol-associated liver disease (AALD) is an umbrella term for a spectrum of diseases resulting from chronic alcohol (e.g. ethanol) abuse ranging in severity from reversible conditions such as alcohol-induced steatosis to advanced and largely irreversible liver pathologies including alcoholic steatohepatitis (ASH), alcoholic hepatitis (AH), fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). AALD is one of the primary causes of chronic liver disease worldwide and accounts for 44% of liver disease deaths in the United States. Drinking rates, both in the United States and globally, have increased year over year for the past three decades, a trend which has resulted in significantly …

Imagining Otherwise: Designing And Implementing A High School Writing Center, Sheldon Cale Krieger

Dissertations

This study explored the work of planning and opening a new high school writing center in a school with a student population predominantly of students of color. The action research study occurred over the first twelve weeks of the writing center opening to better understand how such work might begin to disrupt oppressive systems and structures inherent in the school site as well as education at large. The arts-based methodology included daily reflective journals, a series of four collages, and document analysis. The study utilized critical imagining as its theoretical framework by combining tenets of critical race theory (CRT) with …

Las Chingonas: An Ecological Approach To Latina Student Mothers’ Journey Through College, Emely Elizabeth Medina-Rodriguez

Dissertations

Women with children are one of the growing student sub-populations in higher education. However, the support student mothers receive in colleges and universities has been historically unreliable and their experiences in college have not been studied in depth. This is especially true for student mothers from minoritized backgrounds with differing racial, ethnic, sexual, gender, and ability identities. This research aims to understand the experiences Latina graduate student mothers from an ecological and critical perspective. Guided by Critical Human Ecology and Black Feminist Thought, eight open-ended interviews were conducted and analyzed. Themes and categories came out of the patterns in the …

Elucidating The Role Of Kmt2d In Her2+ Breast Cancer, Emily Ma

Dissertations

Breast cancer is the second leading cause of cancer-related deaths among women in the US. Histone modifications are common epigenetic changes that have been implicated in several breast cancers, including HER2+ breast cancers. Current therapies, such as trastuzumab, block the HER2 receptor to reduce tumor growth. Unfortunately, HER2+ breast cancers have found ways to overcome these therapies, leading to tumor resistance, metastases, and poor survival outcomes. A better understanding of the underlying mechanisms contributing to HER2+ breast cancer resistance may lead to the discovery of novel therapeutic strategies to improve patient outcomes.One prognostic marker for poor survival in women with …

The Souls Of Black Folks In The Twenty-First Century: Self-Efficacy, Grit, And Their Development In Low-Income Urban Black Youth, Amzie Moore

Dissertations

Self-efficacy and grit have shown to be internal resources for African American youth, particularly urban low-income youth living in high crime and high poverty communities. This dissertation is a quasi-experimental, longitudinal, and mix method study, which evaluated a cross-age peer mentoring program. This evaluation was to examine if youth mentors’ attendance in the program for one year predicted increases in their self-efficacy and grit. The results of the study revealed that age significantly interacted with youth attendance, predicting increases in self-efficacy. Findings from the qualitative analyses illustrated that the peer-mentoring program strengthened culturally-relevant self-efficacy and grit among youth mentors.

Unlocking Desistance: The Role Of Executive Functioning In The Rehabilitation Of Correctional Populations, Danielle Nesi

Dissertations

In a secondary analysis of data collected by Fishbein and Sheppard (2006), the current study sought to explore the relationships among age, executive functioning and antisocial behavior (e.g., changes in institutional infractions, self-reported aggression and reactivity) among a sample of incarcerated men enrolled in a correctional Cognitive Behavioral Therapy (CBT) program between 2003 and 2005. Specifically, the current study examined whether baseline executive abilities predicted misconduct and whether this relationship was mediated by treatment engagement. The relationships among age, treatment engagement, and changes in executive functioning post-treatment were also considered. It was predicted that improvements in executive functioning would vary …

Constructing Engineering Knowledge Through Tinkering, Reflection, And Digital Storytelling, Lauren C. Pagano

Dissertations

Educators and researchers suggest that informal learning activities in museums, libraries, and families’ homes can promote children’s science, technology, engineering, and mathematics (STEM) learning (Sobel & Jipson, 2016). Tinkering, a form of hands-on problem-solving involving real tools and materials, is one way to engage families in engineering design processes. However, tinkering activities vary greatly in terms of the goals presented, the resources available, and opportunities to test (Bevan, 2017). Across three studies, we examined how variations in tinkering exhibit design and parent-child interaction relate to children’s memory and STEM learning. In Study 1, we examined the structure and content of …

Leveraging Moral Foundations To Increase Covid-19 Vaccination, Cara Elizabeth Ray

Dissertations

Despite the vast majority of the eligible U.S. adult population being vaccinated against COVID-19, geographical clusters of unvaccinated individuals pose a substantial risk of outbreak. It is important to encourage as many individuals as possible to vaccinate against COVID-19 to reduce its spread and severity. Past research has identified endorsement of the purity and liberty moral foundations – intuitive domains of moral concern – as predictors of vaccine hesitancy and political conservatism, while conservatism is itself associated with vaccine hesitancy. Across two online surveys, I examined the effects of a message invoking the purity and liberty foundations as well as …

White Enigma: Opacity, Perspective, And The Theological Formation Of White Subjectivity, Nathan David Pederson

Dissertations

I argue that examining the concept of “opacity” can hold together a growing tension in a contemporary phenomenology of whiteness: on the one hand, an insistence that whiteness is subjective and habitual; on the other, the insistence that whiteness is also an active, objective world horizon or ontologizing force that shapes the subject. In making this argument, I explain how the notion of opacity shapes a hermeneutical phenomenology of whiteness that can wrestle with how whiteness hides itself as benign through utilizing a symbolism of evil within theological discourse, even as it can come to function more concretely in the …

The Role Of Glycogen Synthase Kinase 3 Β (Gsk-3Β) At The Cardiac Myofilament, Marisa Jean Stachowski

Dissertations

Altered kinase activity and localization is gaining appreciation as a mechanism contributing to cardiovascular disease. Previous work suggests that the kinase glycogen synthase kinase 3 β (GSK-3β) regulates contractile function of the myofilament, but this work was performed in vitro. The goal of this work was to investigate GSK-3β’s in vivo role in regulating myofilament function, the mechanisms involved, and the translational relevance in disease. GSK-3β’s myofilament localization was confirmed in wild type mouse and human tissue via western blot of myofilament enriched tissue and immunofluorescence. These experiments also revealed that GSK-3β phosphorylated at Y216 binds to the z-disc. We …

Healing Earth In A Time Of Crisis: Curriculum For Integral Ecology, Caleb Steindam

Dissertations

This intrinsic multiple case study examined secondary- and university-level educators’ experiences teaching with Healing Earth, a curriculum developed by the International Jesuit Ecology Project at Loyola University Chicago, which merges scientific, social, spiritual, and ethical analyses of pressing ecological issues. Based on the conceptual framework of integral ecology, Healing Earth is a response to Pope Francis’s (2015a) call for “a new way of thinking about human beings, life, society and our relationship with nature” (§215).

This study primarily consisted of in-depth interviews with educators who have used Healing Earth in a variety of secondary and post-secondary Catholic educational contexts. A …

Turn Not Thine Eyes: Holy Faces, Saving Gazes, And The Theology Of Attention, Jacob W. Torbeck

Dissertations

Jacob W. TorbeckLoyola University Chicago TURN NOT THINE EYES: HOLY FACES, SAVING GAZES, AND THE THEOLOGY OF ATTENTION Theoretical Theologies and Practical Theologies have historically been contrasted with one another as distinct but connected disciplines, a contrast with roots in the figures of Plato and Aristotle, or Mary and Martha. Over the centuries, with the increasing ability of theologians to specialize, theoretical theologians have accused practical theologians as ignoring spiritual realities, while practical theologians have accused theoretical theologians of ignoring material realities. This dissertation puts forward a theological exposition of the notion of contemplative attention that demonstrates the unity and …

A Radically Weak (I)Ncounter: Dorothy Day, The Catholic Worker, And Overcoming Otherness, An Anatheistic Argument For A Political Theology Based In Community, Martin Tomszak

Dissertations

The central goal of this dissertation is to find a way to do theology otherwise; to emphasize the need for radical community within the publics of the Church, the academy, and wider society; and to take seriously what the developing genre of radical political theology has to offer the realm of theo-ethics at both a popular and academic level. Through my chosen lens of anatheistic theology and an emphasis on radical lay community, this work aims to evoke genuine conversation about how the Church, the Catholic Worker Movement, and postmodern critical theory might fit together to address the central concerns …

It Doesn’T Get Better With Time: The Effect Of Housing Insecurity On Rearrest In Polk And Palm Beach County, Quintin Williams

Dissertations

Housing insecurity is one of the main drivers of poverty and inequality in contemporary urban society. We know that this insecurity contributes to poor outcomes for the individuals experiencing it. We know less about how this housing insecurity impacts contact with the criminal justice system. Using event history analysis, this study assesses the effects of housing insecurity in Polk County Iowa and Palm Beach County Florida. Results confirm that housing insecurity increases the risk of being rearrested each day a person is without stable housing. These findings reveal that lack of access to safe, affordable, and stable housing not only …

Does Co-Speech Gesture Support Children’S Analogical Reasoning? An Investigation Into The Differential Effects Of Gesture On Learning, Amy Michelle Wilkinson

Dissertations

A well-established conceptualization of academic capitalism is rooted in the marriage of economic theory and critical social. Significantly, academic capitalism links economic dimensions with the political-ideological transformations of U.S. society associated with the fall of communism and the rise of neoliberalism. Academic capitalism is based on a recognition of the paradoxical nature of higher education and offers a lens through which to examine the ways in which institutions in the United States have come to prioritize learning for the labor market as a private good within the new global economy, while also becoming less beholden to the notion of learning …

Chicago Community Area Data, 1930-2010, Nate Falling, Jacob Nelson, Miguel Torres, Richard T. Melstrom

School of Environmental Sustainability: Faculty Publications and Other Works

We are releasing a set of community area
statistics collected from fact book and census
profile data series. These statistics are in the file
Chicago_Community_Area_Data_1930-2010,
which is available from the attached dataset. The statistics do not reflect all of the
data contained in the historical sources.
Additional digitized data can be found at
https://robparal.com/chicago-data/.

Determination Of The Ecological Water Quality In The Orienco Stream Using Benthic Macroinvertebrates In The Northern Ecuadorian Amazon, Federico Sinche, Manuel Cabrera, Lenin Vaca, Edin Segura, Pablo Carrera

School of Environmental Sustainability: Faculty Publications and Other Works

In recent years, pollution of watercourses in nearby protected ecosystems has increased due to urbanization. Standard physiochemical methods and probes are one way to monitor watercourses for quality. However, they often do not provide the full ecological status of the body of water. In this work, we set out to assess the ecological water quality of an urban stream by using benthic macroinvertebrates as bioindicators. We conducted the work on the Orienco stream in Lago Agrio in the province of Sucumbíos in the Northern Ecuadorian Amazon (NEA). The stream has become a sink of raw domestic sanitary wastewater from rural …

Thinking, Meaning, And Truth: Arendt On Heidegger And The Possibility Of Critique, Jennifer Gaffney

Philosophy: Faculty Publications and Other Works

No abstract provided.

“An Umbrella For All Things”: Black Daughter's Sexual Decisions And Paternal Engagement, Marquitta S. Dorsey

Social Work: School of Social Work Faculty Publications and Other Works

Objective: The purpose of this article is to highlight the value of Black fathers to the sexual decision-making processes among Black adolescent and young adult daughters. Background: Various contextual factors, such as fewer sexual health resources in poorer communities and federal funding cuts to family planning service agencies, ultimately contribute to the sexual health decision-making of adolescent young women and may be linked to sexual health disparities among Black adolescent women. Recent studies have reported the protective nature of a Black father’s engagement to be beneficial to the behavioral outcomes of adolescent daughters. Method: Findings from 17 semistructured interviews conducted …

Strategies To Mitigate The Effects Of Negative Political Rhetoric On Service Providers: A Study In Two Refugee-Serving Organizations, Maria V. Wathen, Charity N. Weishar, Patrick L.F. Decker

Social Work: School of Social Work Faculty Publications and Other Works

This paper explores the strategies that staff at two refugee-serving organizations found helpful in mitigating their increased distress from negative political rhetoric aimed at their clients. Results point to the importance of organizational acknowledgement of the distress. Additionally, staff perceived that intentionally focused organizational interventions can mitigate the emotional impacts of negative rhetoric. Finally, strategies employees used to lessen their distress and regain a sense of efficacy included recommitment to the mission, advocacy for refugees among family and friends, strong reliance on religious faith in coping, and an avoidance of the rhetoric by decreasing engagement with news and social media.

Casting And Splinting Options For Pseudo-Jones Avulsion Fractures: An Evidence-To-Practice Review, Amber M. Kingsley, Aysha B. Reyes, Zachary K. Winkelmann

Clinical Practice in Athletic Training

Avulsion fractures of the fifth metatarsal bone occur when a portion of the bone is broken or pulled off the rest of the bone. These fractures are often seen in athletes, especially those of a young age. Avulsion fractures of the fifth metatarsal bone are commonly treated non-surgically with immobilization of the foot. There are several different options for immobilization of the foot with no clear result as to which immobilization method is the most effective. The purpose of this evidence-to-practice review was to summarize a systematic review on comparative outcomes of immobilization interventions on avulsion fractures of the fifth …

Fairness And Inclusion For Users Of Surface Transport—An Exploratory Thematic Study For Irish Users, Ajeni Ari, Maria Chiara Leva, Lorraine D'Arcy, Mary Kinahan

Articles

This paper explores the conditions of public transport with respect to user accessibility, design of infrastructure, and safety from a gendered perspective. Our investigation aims to understand the factors that direct a citizen’s choice of whether or not to use public transport. Our discussion is focused on gender disparities among user experiences, so we confine our focus to that of women’s perspectives and their experiences with public transport use. A framework for our discussion was formed with consideration of the theoretical aspects of fairness, justice, and gender in transport, as well as user statistics. We identified several spaces where public …

Table Of Contents

Journal of Business & Technology Law

No abstract provided.

Rear Window: The Future Of Hollywood Contracting In The Streaming Age, Miller Friedman

Journal of Business & Technology Law

No abstract provided.

Tidal Current Turbine Blade Optimisation With Improved Blade Element Momentum Theory And A Non-Dominated Sorting Genetic Algorithm, Eng Jet Yeo, David Kennedy, Fergal O'Rourke

Articles

Tidal current energy has the advantage of predictability over most of the other renewable energy resources. However, due to the harsh operating environment and complicated site conditions, developments in this domain have been gradual. Paramount to these points is device design and optimisation of hydrodynamic performance. Recent developments in the correction models of BEM theory have further improved the accuracy of the prediction model. Using an improved blade element momentum theory model that is capable of accurately capturing the downwash angle and combining it with a well-developed and reliable non-dominated sorting genetic algorithm model, an effective and efficient tidal current …

Building Performance - Societal Drive, Programme And Symposium, Joseph Little, Patrick Daly

Articles

Society is increasingly looking at the construction industry to mitigate the environmental crisis and solve the housing crisis through wholesale embrace of three broad sets of challenges. The MSc in Building Performance (Energy Efficiency in Design) (MSc BP(EED)) was created in 2017 to provide significant upskilling in the knowledge, skills, and software applications of building design professionals so that they can meet these challenges, while creating compliant, sustainable, super-low energy, new and renovated buildings. The delivery of the programme supports upskilling of employed building design professionals at Masters level, encouraging a minority to develop their capacity and interest in research …

"What's In A Name?”: The Use Of Instructional Design In Overcoming Terminology Barriers Associated With Dark Patterns, Andrea Curley, Damian Gordon, Dympna O'Sullivan

Conference Papers

Many users experience a phenomena when they are shopping on-line where they feel they are being pressured to either spend more money than they had intended, or to share more personal data than they wanted. In academic circles we use the term “Dark Patterns” to describe these deceptive practices, and categorize them as being within the discipline of User Experience (Narayanan, 2020). As academics it is important to name phenomena, and to categorize them, so that we can discuss and analyze these issues. However, this particular topic is one that all users should be made aware of when interacting online, …

Will Treating Progressive Myopia Overwhelm The Eye Care Workforce? A Workforce Modelling Study, Gareth Lingham, James Loughman, Stella Kuzmenko, Matilda Biba, Daniel Ian Flitcroft

Articles

Purpose

Treatments for myopia progression are now available, but implementing these into clinical practice will place a burden on the eye care workforce. This study estimated the full-time equivalent (FTE) workforce required to implement myopia control treatments in the UK and Ireland.

Methods

To estimate the number of 6- to 21-year-olds with myopia, two models utilising separate data sources were developed. The examination-based model used: (1) the number of primary care eye examinations conducted annually and (2) the proportion of these that are for myopic young people. The prevalence-based model used epidemiological data on the age-specific prevalence of myopia. The …

Viruses, Vaccines, And The Erotics Of Risk In Latinx Hiv Stories And Covid-19, Dr. Suzanne Bost

English: Faculty Publications and Other Works

In 2019, I published Shared Selves: Latinx Memoir and Ethical Alternatives to Humanism (University of Illinois Press), in which I discuss contagion as a metaphor for embracing our shared materiality with others. Six months later, during the Covid-19 pandemic, neighbors were crossing streets to avoid each other. Social distancing is, counterintuitively, asking us to view separation and seclusion as forms of solidarity. But how can we be solid if we are oriented against each other? Isolation itself has become contagious: sharing repulsion and rejection, measuring six feet of “social” distance from others. These spaces are made up of a variety …

Towards An Active Foveated Approach To Computer Vision, Dario Dematties, Silvio Rizzi, George K. Thiruvathukal, Alejandro Javier Wainselboim

Computer Science: Faculty Publications and Other Works

In this paper, a series of experimental methods are presented explaining a new approach towards active foveated Computer Vision (CV). This is a collaborative effort between researchers at CONICET Mendoza Technological Scientific Center from Argentina, Argonne National Laboratory (ANL), and Loyola University Chicago from the US. The aim is to advance new CV approaches more in line with those found in biological agents in order to bring novel solutions to the main problems faced by current CV applications. Basically this work enhance Self-supervised (SS) learning, incorporating foveated vision plus saccadic behavior in order to improve training and computational efficiency without …