Digital Commons Network^™

Look, But Don’T Touch: Impact Of Covid-19 On The Nicu Caregiver, Rebecca C. Otwell-Dove

Electronic Theses and Dissertations

Admission of an infant into the neonatal intensive care unit (NICU) is an experience that has been associated with a variety of both positive and negative health outcomes for parent and child. While both the setting name and the admitted population alludes to a sole focus on the affected infant, what often remains underrecognized is the impact on the ones who care for the newborn long before and longer after their NICU stay. Given the recency and unprecedented impact of the COVID-19 pandemic, very little research has examined the impact of COVID-19-specific stress on the experience of parents of infants …

Evaluating Bat Roost Abundance: A Comparison Of Drone-Acquired Thermal Imagery And Acoustic Estimates With Visual Observations, Karah Jaffe

Electronic Theses and Dissertations

Roosts provide an opportunity to census philopatric populations of bats. Comparing the efficacy of traditional methods with novel methods can provide guidance on the use of new technologies in the field. This project aims to compare the count efficacy of external emergence methodologies, i.e., drone-acquired thermal imagery, acoustic estimates, and visual counts. Surveys were conducted ten nights at two emergence sites and synchronized to compare counts. Acoustic estimates could not be established as there was a weak prediction of the linear relationship between root-mean-square pressure and emergence count; therefore, this method was removed from the comparative analysis. A linear mixed-effects …

Adaptation Of Instructional Strategies And Practices During A Pandemic, Lacy E. York Hughes

Electronic Theses and Dissertations

The purpose of this study was to explore the stories of identified, effective middle school teachers as they experienced changes in instructional strategies and practices as a result of an identified crisis, COVID-19. Although there has been little documentation in the literature specifically regarding adapting instructional strategies and practices as a result of crises, crisis management, change theory, mindset theory, adaptation, and teacher effectiveness characteristics became the framework through which to interpret the data.

Data collection strategies included one-on-one, semi-structured interviews with a total of eight participants, two principals and six teachers, who met specific research participation criteria. Analysis of …

Validation Of The 40 Hz Auditory Steady State Response As A Pharmacodynamic Biomarker Of Evoked Neural Synchrony, Muhammad Ummear Raza

Electronic Theses and Dissertations

Schizophrenia is a troubling and severe mental illness that is only incompletely treated by currently available drugs. New drug development is hindered by a scarcity of functionally relevant pharmacodynamic biomarkers that are translatable across preclinical and human subjects. Although psychosis is a major feature of schizophrenia, cognitive and negative symptoms determine the long-term functional outcomes for patients. Stimulus-evoked neural synchrony at gamma (~ 40 Hz) frequency plays an important role in the processing and integration of sensory information. Not surprisingly, schizophrenia patients show deficits in gamma oscillations. NMDA receptor (NMDAR) activation on fast-spiking parvalbumin-positive interneurons is deemed important for the …

Adverse Childhood Experiences And Quality Of Life: A Mediating Role Of Physical Activity And Executive Function, Loni Parrish

Electronic Theses and Dissertations

ACEs have been associated with heightened risk for a range of chronic health problems, substance use, and cognition in adulthood (Center for Disease Control (CDC), 2019; Hinojosa et al., 2017). One potential protective factor is physical activity (McEwen, 2016; Wu et al., 2013). Physical activity is associated with sustaining overall health, improving mental health by reducing symptoms of depression and anxiety (Murri et al., 2019; Sharma et al., 2006; Tasci et al., 2019), and maintaining a healthy body weight and BMI (WHO, 2021). Therefore, this study examined whether barriers to physical activity, physical activity levels, and executive outcomes serve as …

The Paleoecology Of High-Elevation Bison In The Greater Yellowstone Ecosystem And Implications For Modern Bison Conservation, Darian Bouvier

Electronic Theses and Dissertations

The national mammal of the United States, the American Bison (Bison bison) was once nearly extinct. Populations have recovered to the degree that thousands roam the Great Plains today. Due to their large numbers and body size, this species has an oversized impact on the ecological communities where it lives and is considered a keystone herbivore in modern North American grasslands. This study explores the detailed, seasonally resolved, paleoecology of seven bison from the Greater Yellowstone Ecosystem during the Late Holocene through stable isotope analyses and species niche modeling. Isotopic analyses of δ¹³C, δ¹⁵N, …

Improved Molecular Detection Tools For The Invasive Crop Pest Helicoverpa Armigera (Hübner), Mitchell D. Rich

All Theses

Helicoverpa armigera is a major crop pest native to Europe, Asia, Australia, and Africa. H. armigera has recently invaded South America and has caused billions of dollars in agricultural losses. It is difficult to differentiate H. armigera from H. zea, a closely-related species native to North and South America. A few genetic tests have been previously developed to detect H. armigera DNA in pooled samples of moth legs. In this study, an improved qPCR melt curve assay with higher detection sensitivity and a field-based recombinase polymerase amplification (RPA) assay were developed for specific detection of H. armigera DNA …

Feature Analysis Of Indus Valley And Dravidian Language Scripts With Similarity Matrices, Sarat Sasank Barla, Sai Surya Sanjay Alamuru, Peter Revesz

School of Computing: Conference and Workshop Papers

This paper investigates the similarity between the Indus Valley script and the Kannada, Malayalam, Tamil, and Telugu scripts that are used to write Dravidian languages. The closeness of these scripts is determined by applying a feature analysis of each sign of these scripts and creating similarity matrices that describe the similarity of any pair of signs from two different scripts. The feature list that we use for the analysis of these Dravidian language-related scripts includes six new features beyond the thirteen features that were used for the study of Minoan Linear A and related scripts by Revesz. These new features …

Metabolite Damage And Damage Control In A Minimal Genome, Drago Haas, Antje M. Thamm, Jiayi Sun, Lili Huang, Lijie Sun, Guillaume A.W. Beaudoin, Kim S. Wise, Claudia Lerma-Ortiz, Steven D. Bruner, Marian Breuer, Zaida Luthey-Schulten, Jiusheng Lin, Mark A. Wilson, Greg Brown, Alexander F. Yakunin, Inna Kurilyak, Jacob Folz, Oliver Fiehn, John I. Glass, Andrew D. Hanson, Christopher S. Henry, Valérie De Crécy-Lagard

Department of Biochemistry: Faculty Publications

Analysis of the genes retained in the minimized Mycoplasma JCVI-Syn3A genome established that systems that repair or preempt metabolite damage are essential to life. Several genes known to have such functions were identified and experimentally validated, including 5-formyltetrahydrofolate cycloligase, coenzyme A (CoA) disulfide reductase, and certain hydrolases. Furthermore, we discovered that an enigmatic YqeK hydrolase domain fused to NadD has a novel proofreading function in NAD synthesis and could double as a MutT-like sanitizing enzyme for the nucleotide pool. Finally, we combined metabolomics and cheminformatics approaches to extend the core metabolic map of JCVI-Syn3A to include promiscuous enzymatic reactions and …

Detection Of Erythroid Progenitors And Erythrocytopathies In Patients With Severe Covid-19 Disease, Mamdouh A. Allahyani, Abdulelah A. Aljuaid, Mazen M. Almehmadi, Ahmad A. Alghamdi, Ibrahim F. Halawani, Abdullah F. Aldairi, Ahmad M. Alharbi, Mohammad H. Albshri, Abdulqader A. Mutwalli, Ayman S. Alhazmi

Saudi Medical Journal

Objectives: To assess the effect of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection on erythropoiesis and red blood cells (RBC) surface markers by evaluating erythroid progenitor cells (CD [cluster of differentiation]71 + /CD235a + ) and RBC surface markers (CD235a and CD36), together with various hematological parameters. Methods: This case-control study includes 47 participants recruited in the study: 30 patients with coronavirus disease 2019 (COVID-19) and 17 healthy individuals. The COVID-19 patients were recruited from the intensive care unit (ICU) of various hospitals in Makkah, Saudi Arabia. Blood samples were collected during July and September 2021. Red blood cells indices …

18s-Nemabase: Curated 18s Rrna Database Of Nematode Sequences, Kaitlin Gattoni, Eli M. S. Gendron, Rebeca Sandoval- Ruiz, Abigail Borgemeier, J. Parr Mcqueen, Rachel M. Shepherd, Dieter Slos, Tom Powers, Dorota L. Porazinska

Department of Plant Pathology: Faculty Publications

Nematodes are the most abundant and diverse animals on the planet but lack representation in biodiversity research. This presents a problem for studying nematode diversity, particularly when molecular tools (i.e., barcoding and metabarcoding) rely on well-populated and curated reference databases, which are absent for nematodes. To improve molecular identification and the assessment of nematode diversity, we created and curated an 18S rRNA database specific to nematodes (18S-NemaBase) using sequences sourced from the most recent publicly available 18S rRNA SILVA v138 database. As part of the curation process, taxonomic strings were standardized to contain a fixed number of taxonomic ranks relevant …

In Vivo Efficacy Of Pyrantel Pamoate As A Post-Exposure Prophylactic For Rat Lungworm (Angiostrongylus Cantonensis), John Jacob, Argon Steel, Lisa Kaluna, Steven Hess, Israel Leinbach, Carmen Antaky, Robert Sugihara, Lindsey Hamilton, Peter Follett, Kathleen Howe, Steven Jacquier, Supakit Wongwiwatthananukit, Susan Jarvi

United States Department of Agriculture Wildlife Services: Staff Publications

Rat lungworm (Angiostrongylus cantonensis) is a neurotropic nematode, and the leading cause of eosinophilic meningitis worldwide. The parasite is usually contracted through ingestion of infected gastropods, often hidden in raw or partially cooked produce. Pharmaceutical grade pyrantel pamoate was evaluated as a post-exposure prophylactic against A. cantonensis. Pyrantel pamoate is readily available over-the-counter in most pharmacies in the USA and possesses anthelmintic activity exclusive to the gastrointestinal tract (GIT). Administering pyrantel pamoate immediately after exposure should theoretically paralyze the larvae in the GIT, causing the larvae to be expelled via peristalsis without entering the systemic circulation. In this study, pyrantel …

Current Ecotoxicity Testing Needs Among Selected U.S. Federal Agencies, Patricia Ceger, Natalia Garcia-Reyero Vinas, David Allen, Elyssa Arnold, Raanan Bloom, Jennifer C. Brennan, Carol Clarke, Karen Eisenreich, Kellie Fay, Jonathan Hamm, Paula F.P. Henry, Katherine E. Horak, Wesley Hunter, Donna Judkins, Patrice Klein, Nicole Kleinstreuer, Kara Koehrn, Carlie A. Lalone, James P. Laurenson, Jessica K. Leet, Anna Lowit, Scott G. Lynn, Teresa Norberg-King, Edward J. Perkins, Elijah J. Petersen, Barnett A. Rattner, Catherine S. Sprankle, Thomas Steeger, Jim E. Warren, Sarah Winfield, Edward Odenkirchen

United States Department of Agriculture Wildlife Services: Staff Publications

U.S. regulatory and research agencies use ecotoxicity test data to assess the hazards associated with substances that may be released into the environment, including but not limited to industrial chemicals, pharmaceuticals, pesticides, food additives, and color additives. These data are used to conduct hazard assessments and evaluate potential risks to aquatic life (e.g., invertebrates, fish), birds, wildlife species, or the environment. To identify opportunities for regulatory uses of non-animal replacements for ecotoxicity tests, the needs and uses for data from tests utilizing animals must first be clarified. Accordingly, the objective of this review was to identify the ecotoxicity test data …

Defining An Epidemiological Landscape That Connects Movement Ecology To Pathogen Transmission And Pace-Of-Life, Kezia Manlove, Mark Wilber, Lauren White, Guillaume Bastille-Rousseau, Anni Yang, Marie L.J. Gilbertson, Meggan E. Craft, Paul C. Cross, George Wittemyer, Kim M. Pepin

United States Department of Agriculture Wildlife Services: Staff Publications

Pathogen transmission depends on host density, mobility and contact. These components emerge from host and pathogen movements that themselves arise through interactions with the surrounding environment. The environment, the emergent host and pathogen movements, and the subsequent patterns of density, mobility and contact form an ‘epidemiological landscape’ connecting the environment to specific locations where transmissions occur. Conventionally, the epidemiological landscape has been described in terms of the geographical coordinates where hosts or pathogens are located. We advocate for an alternative approach that relates those locations to attributes of the local environment. Environmental descriptions can strengthen epidemiological forecasts by allowing for …

A Study On The Role Of Innovative Enterprise-Farmer Contracts In The Sustainable Development Of Agricultural Industrialization - A Perspective Based On Ghm Theroy, Yanjie Wu

Dissertations and Theses Collection (Open Access)

Agricultural industrialization is the primary channel to promote large-scale agricultural production, intensive processing, and marketing, enhancing agricultural production efficiency. In the long run, promoting agricultural industrialization is conducive to the deep integration of primary, secondary, and tertiary industries. It can improve the comparative efficiency of agriculture and reduce poverty by promoting the employment of agricultural labor and the flow of production factors between urban and rural areas. The model of “leading enterprises+farmers” is a significant agricultural industrialization business model. In China, the development of agricultural industrialization is late and fast, and more problems have emerged in the development. The contractual …

Taking Aim: The Evolution Of Women In Competitive Shooting Sports In The 20th Century United States, Alena Rose-Marie Buczynski

Masters Theses

Throughout history, women have been overlooked, discounted, and ignored for their skills and abilities as competitive and professional athletes. Competitive shooting sports were popular in the United States; however, men excluded women from participating in many of these activities until the early 19th century, when America saw the rise of famous markswomen such as Annie Oakley, Calamity Jane, and Lillian Smith. These women challenged the masculinity of the sport of shooting and bested many of their male counterparts as they traveled and performed across the United States. In the 1970s, women found themselves entering the Olympic arena of competitive shooting …

Neurogenesis And Functional Recovery In The Adult Mouse Retina Using An Alpha7 Nachr Agonist After Blast Exposure, Jake Bennett Spitsbergen

Masters Theses

Previous studies have provided evidence that eyedrop application of the selective α7 nicotinic acetylcholine receptor agonist, PNU-282987, induces neurogenesis and regeneration of retinal neurons from Müller glia in adult rodents. The objectives of this research include: 1) examination of the cellular and functional damage associated with ocular blast exposure, and 2) evaluation of structural and functional recovery post PNU-282987 treatment. Significant ocular blast damage was induced in adult mice after exposure to a single blast of 35 psi to the left eye. Blast-exposed transgenic mice expressing tdTomato Müller glia were treated daily with eyedrops containing PNU-282987 for 4 weeks following …

Kinetic And Structural Characterization Of Pseudooxynicotine Amine Oxidase From Pseudomonas Putida S16, Vishakha Choudhary

Masters Theses

Our laboratory has previously shown that nicotine oxidoreductase (NicA2), a member of the flavin-containing amine oxidase family, uses a cytochrome c protein (CycN) as its electron acceptor rather than characteristically accepted molecular oxygen. Within the Pseudomonas putida S16 genome, the nicA2 gene forms an operon with cycN and pseudooxynicotine amine oxidase (pnao), another flavin containing amine oxidase enzyme. The first two steps in the nicotine catabolism pathway are catabolized by NicA2 and Pnao. Through redox chemistry, NicA2 converts nicotine to pseudooxynicotine and Pnao converts pseudooxynicotine to 3-succinoylsemialdehyde-pyridine. In this thesis, we characterize the kinetic and structural properties of …

Digital Pastoral, Rebecca Holifield

Master's Theses

Digital Pastoral is a collection of original poems and a creative nonfiction essay, accompanied by a critical introduction.

Investigation Of Dead Ocean Quahogs (Arctica Islandica) Shells On The Mid-Atlantic Bight Continental Shelf, Alyssa Leclaire

Master's Theses

Ocean quahogs, Arctica islandica, are a long-lived, widely dispersed, biomass dominate in the Mid-Atlantic; therefore, quahog shells are valuable resources for studying climate change over time. Recently, dead ocean quahog shells were discovered south and inshore of the present biogeographic range of this animal. The presence of ocean quahog shells outside the current range is presumably a consequence of past regressions and transgressions of the Cold Pool, the bottom-trapped, cool body of water that allows boreal animals to live at lower latitudes. Dead ocean quahog shells were collected offshore of the DelMarVa Peninsula then radiocarbon-dated, evaluated for taphonomic condition, …

Infidelity And The Bioecological Protective Factors For Mental Health: A Longitudinal Investigation, Lindy Williams

Master's Theses

Infidelity is an important topic of research due to the profound effects on the individual experiencing the trauma. Through the lens of bioecological systems and betrayal trauma, the impact of infidelity on mental health is examined in relation to the most proximal systems to an individual which include personality traits such as agreeableness and neuroticism as well as support from friends, family, and community. This research explores the hypotheses that more support leads to more positive mental health outcomes after the experience of infidelity and the possibility that support from friends, family, and community may buffer specific personality traits and …

Effects Of Shoreline Development And Freshwater Discharge On Nekton Assemblage And Trophic Structure In A Northern Gulf Of Mexico Estuary, Glenn Schumacher

Master's Theses

Coastal salt marshes support a diversity of nekton and facilitate critical ecosystem functions but are threatened by shoreline development and climate change. Therefore, coastal ecosystem managers have begun incentivizing the use of living shorelines (LS), erosion control structures incorporating native plantings, to mitigate ecological consequences of marsh loss. However, post-restoration climate changes may shift habitat templates and negate positive effects of ecosystem restoration. I evaluated the ecology nekton along LS, natural marshes, hardened shorelines and greyed shorelines within Biloxi Bay, Mississippi, during a high freshwater discharge (HFD) period by comparing nekton assemblage (using species richness, Shannon-Wiener diversity, and relative abundance), …

A Bioarchaeological Investigation Of The Courtney-Anderson Cemetery, Lauren Scott

Master's Theses

Located in Perry County, Mississippi, the Anderson Family Cemetery represents an abandoned turn-of-the-century Piney Woods cemetery. The cemetery is located on land once owned by the Courtney and Anderson families, who farmed the area until it was taken under eminent domain by the United States government in 1942. The purpose of this thesis is to present three osteobiographies created from human remains and material culture recovered from three graves excavated from within the cemetery in 2022 to explore the lifeways of rural Piney Woods families of Mississippi at the turn-of-the-century.

Among the graves explored, one did not contain evidence of …

Optimising Predictive Models To Prioritise Viral Discovery In Zoonotic Reservoirs, Daniel J. Becker, Gregory F. Albery, Anna R. Sjodin, Timothée Poisot, Laura M. Bergner, Binqi Chen, Lily E. Cohen, Tad Dallas, Evan A. Eskew, Anna C. Fagre, Maxwell J. Farrell, Sarah Guth, Barbara A. Han, Nancy B. Simmons, Michiel Stock, Emma C. Teeling, Colin J. Carlson

Faculty Publications

Despite the global investment in One Health disease surveillance, it remains difficult and costly to identify and monitor the wildlife reservoirs of novel zoonotic viruses. Statistical models can guide sampling target prioritisation, but the predictions from any given model might be highly uncertain; moreover, systematic model validation is rare, and the drivers of model performance are consequently under-documented. Here, we use the bat hosts of betacoronaviruses as a case study for the data-driven process of comparing and validating predictive models of probable reservoir hosts. In early 2020, we generated an ensemble of eight statistical models that predicted host–virus associations and …

The Intersections Of Sex And Inequality In A Mixed Status Industrial London Sample, Anna Green

Boise State University Theses and Dissertations

Saint Pancras Burial Ground and its inhumated priests, paupers, aristocrats, and migrants provide a unique perspective into the interactions between sex and inequality in 18th and 19th century industrial London. Frequencies of caries, dental calculus, periodontal disease, linear enamel hypoplasia, periapical lesions, tuberculosis, treponematosis, rickets, and trauma among 224 females from St. Pancras were compared to 27 low-status females from Crossbones Burial Ground and 74 primarily high-status females from Chelsea Old Church Cemetery. Based on the information known about those buried at St. Pancras, it was hypothesized that the frequencies of health indicators in St. Pancras should fall between the …

La Asignación De Género De Los Préstamos En El Sureste De Tejas [The Gender Assignment Of Loans In Southeast Texas], Elsa Guadalupe Magana Orozco

Theses and Dissertations

En esta investigación se examina la asignación de género de préstamos del inglés al español en el Valle del Río Grande de Tejas basándose en 32 entrevistas sociolingüistas del Corpus bilingüe del Valle (Christoffersen y Bessett, 2019). Se han llegado a reconocer tres posibles factores que determinan la asignación de género (masculino o femenino) de los préstamos, tales como el sexo biológico, el género fonológico y el género analógico (Poplack, 1982; DuBord, 2004; Montés-Alcalá y Lapidus Shin, 2011). Los resultados muestran un total de 692 préstamos la mayoría fue asignado el género masculino un 50%, mientras 33% fue asignado el …

Mobile Health With Head-Worn Devices: Challenges And Opportunities, Andrea Ferlini, Dong Ma, Lorena Qendro, Cecilia Mascolo

Research Collection School Of Computing and Information Systems

Monitoring human behavior and health status using mobile devices, a.k.a. Mobile Health, has gained increasing attention from both academia and industry in recent years. It allows imperceptible health tracking from the users and remote health management from the healthcare service providers. Headworn devices, such as earbuds, glasses, and BCIs (Brain Computer Interfaces), exhibit great potential for mobile health due to their advantageous wearing position, the human head, which is motion-resilient and full of human bio-signals. Although initial attempts have been conducted for different healthcare applications with head-worn devices, this fast-growing area is still under-explored and retains great promises. With this …

August 2022 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Conformational Selection Governs Carrier Domain Positioning In Staphylococcus Aureus Pyruvate Carboxylase, Joshua H. Hakala, Amanda J. Laseke, Anya Lei Koza, Martin St. Maurice

Biological Sciences Faculty Research and Publications

Biotin-dependent enzymes employ a carrier domain to efficiently transport reaction intermediates between distant active sites. The translocation of this carrier domain is critical to the interpretation of kinetic and structural studies, but there have been few direct attempts to investigate the dynamic interplay between ligand binding and carrier domain positioning in biotin-dependent enzymes. Pyruvate carboxylase (PC) catalyzes the MgATP-dependent carboxylation of pyruvate where the biotinylated carrier domain must translocate ∼70 Å from the biotin carboxylase domain to the carboxyltransferase domain. Many prior studies have assumed that carrier domain movement is governed by ligand-induced conformational changes, but the mechanism underlying this …

A Genome-Wide Association Study Of Obstructive Heart Defects Among Participants In The National Birth Defects Prevention Study, Sara R Rashkin, Mario Cleves, Gary M Shaw, Wendy N Nembhard, Eirini Nestoridi, Mary M Jenkins, Paul A Romitti, Xiang-Yang Lou, Marilyn L Browne, Laura E Mitchell, Andrew F Olshan, Kevin Lomangino, Sudeepa Bhattacharyya, John S Witte, Charlotte A Hobbs

Faculty, Staff and Student Publications

Obstructive heart defects (OHDs) share common structural lesions in arteries and cardiac valves, accounting for ~25% of all congenital heart defects. OHDs are highly heritable, resulting from interplay among maternal exposures, genetic susceptibilities, and epigenetic phenomena. A genome-wide association study was conducted in National Birth Defects Prevention Study participants (N