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Beyond Green: Re-Reading "Wicked" As Anthropological Text, Tan Gia Bao Huynh Apr 2026

Beyond Green: Re-Reading "Wicked" As Anthropological Text, Tan Gia Bao Huynh

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

This paper examines "Wicked" through the lens of cultural borderlands, revealing how the musical dramatizes the creation and navigation of social boundaries. By analyzing Elphaba's journey, the research demonstrates how her green skin serves as a powerful metaphor for cultural otherness, while her experiences at Shiz University and beyond illustrate strategies of resistance, accommodation, and identity formation familiar to those navigating between dominant and marginalized spaces. Particularly significant is the paper's examination of Oz's propaganda system, which demonstrates how cultures manufacture monsters and heroes through selective storytelling and public ritual. This analysis offers fresh insights into "Wicked's" enduring appeal, suggesting …


Development Of Lkpd Based On Vba Powerpoint Assisted Discovery Learning Model To Improve Creative Thinking Ability And Learning Independence Of Grade Iv Elementary School Students, Neng Ira Sonia, Asep Ikin Sugandi, Masta Hutajulu Apr 2026

Development Of Lkpd Based On Vba Powerpoint Assisted Discovery Learning Model To Improve Creative Thinking Ability And Learning Independence Of Grade Iv Elementary School Students, Neng Ira Sonia, Asep Ikin Sugandi, Masta Hutajulu

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Pembelajaran di sekolah dasar masih menghadapi banyak masalah berupa rendahnya kemampuan berpikir kreatif dan kemandirian belajar siswa karena penggunaan LKPD yang belum sepenuhnya mendorong keterlibatan aktif siswa. Oleh karena itu, perlu dikembangkan bahan ajar yang inovatif dan kontekstual. Penelitian ini bertujuan untuk mengembangkan Lembar Kerja Siswa (LKPD) menggunakan model pembelajaran Discovery Learning dengan bantuan PowerPoint VBA dan menguji kelayakan serta efektivitasnya dalam meningkatkan kemampuan berpikir kreatif dan kemandirian belajar siswa kelas IV sekolah dasar. Metode penelitian yang digunakan adalah Penelitian dan Pengembangan dengan tahapan analisis, pengumpulan data, desain produk, validasi, uji coba terbatas, uji coba ekstensif, dan pengujian produk. Subjek …


Changes In Depression, Eating, Sleep, And Emotion Regulation In Air Force Rotc Cadets After The 12-Wk Star Training Program, Antonella V. Schwarz, Hunter Haynes, Sheena Puleali’I, Jacob Mota, Molly F. Johnson, Maria G. Kaylor, Andrew Addison, Robyn Braun-Trocchio, Austin J. Graybeal Apr 2026

Changes In Depression, Eating, Sleep, And Emotion Regulation In Air Force Rotc Cadets After The 12-Wk Star Training Program, Antonella V. Schwarz, Hunter Haynes, Sheena Puleali’I, Jacob Mota, Molly F. Johnson, Maria G. Kaylor, Andrew Addison, Robyn Braun-Trocchio, Austin J. Graybeal

Faculty Publications

Introduction: – Reserve Officer Training Corps (ROTC) cadets must balance collegiate demands with military preparation, leaving them vulnerable to psychological stressors. While structured strength and conditioning (S&C) programs enhance physical readiness, their impact on psychological health in cadet populations remains unclear. This study evaluated changes in depression, eating behaviors, sleep quality, and emotion regulation during a 12-wk S&C program. Methods: – Forty-nine U.S. Air Force ROTC cadets (21 female, 28 male; age: 20 ± 2 yr; body mass index: 24.2 ± 4.4 kg·m−2; body fat %: 27.1 ± 9.0%) completed the Supporting Tactical Athlete Readiness (STAR) program, a …


Biomass Demineralization: A Critical Need For Future Biorefineries, Leoncio Santiago-Martínez, Styliani Avraamidou, Alejandro Ayala-Cortés, Ruth Azike, Santanu Bakshi, Chumki Banik, Ezra Bar Ziv, Fei Long, Rebecca Ong, Et Al. Apr 2026

Biomass Demineralization: A Critical Need For Future Biorefineries, Leoncio Santiago-Martínez, Styliani Avraamidou, Alejandro Ayala-Cortés, Ruth Azike, Santanu Bakshi, Chumki Banik, Ezra Bar Ziv, Fei Long, Rebecca Ong, Et Al.

Michigan Tech Publications

Biomass contains up to 14 essential elements that serve as nutrients for plant growth and development, including photosynthesis and enzyme functionalities. These elements in different chemical forms (e.g., minerals) constitute the inorganic fraction of biomass and can cause operational issues in thermal and biochemical biomass conversion technologies. In biomass gasification and pyrolysis processes, for instance, inorganics can cause fouling, tar formation, and corrosion. In catalytic and biochemical processes, inorganics can poison catalysts, alter biochemical pathways, and modify product yields and selectivity. This review provides an overview of the inorganic content in biomass feedstocks, the critical role inorganics play in plant …


2026-04-08 Whidbey Lab Leads Women’S Health Research On Campus, Kaitlyn Delfs Apr 2026

2026-04-08 Whidbey Lab Leads Women’S Health Research On Campus, Kaitlyn Delfs

The Spectator Online

No abstract provided.


Commonwealth Times 2026-04-08 Apr 2026

Commonwealth Times 2026-04-08

Commonwealth Times, 1969-

No abstract provided.


Daily Eastern News: April 08, 2026, Eastern Illinois University Apr 2026

Daily Eastern News: April 08, 2026, Eastern Illinois University

Daily Eastern News: 2025-2026

No abstract provided.


The Lumberjack, April 08, 2026 Apr 2026

The Lumberjack, April 08, 2026

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.


Advancing The Study Of Politics And The Brain: Targets For Research On Neurology And Political Behavior, Glenn W. Rainey Jr. Apr 2026

Advancing The Study Of Politics And The Brain: Targets For Research On Neurology And Political Behavior, Glenn W. Rainey Jr.

Commonwealth Review of Political Science

In this paper I argue that advancing research on neurology is creating important opportunities for political scientists to integrate its findings into their research, particularly with regard to the effects of emotional processes on political behavior.  I provide a general background on neural anatomy, genetics, and neurobiological chemicals, and I briefly review techniques of neurological research, the findings that have been developing, and the limitations on the research. I provide an overview of selected key neural anatomy, and neurotransmitters and hormones, that play a role in neurological functions, and particularly in the development and expression of emotions.  I then suggest …


Analysis Of The Effects Of Magnetic Field, Heat Transfer, And Thermal Radiation On Blood Flow Through Bifurcated Artery To Enhance Tumor Treatments, Abdullahi Isah, Dauda Gulibur Yakubu, Ali Musa Apr 2026

Analysis Of The Effects Of Magnetic Field, Heat Transfer, And Thermal Radiation On Blood Flow Through Bifurcated Artery To Enhance Tumor Treatments, Abdullahi Isah, Dauda Gulibur Yakubu, Ali Musa

Tanzania Journal of Science

The work presents the effects of some pertinent parameters on blood flow through bifurcated artery to enhance tumor treatments. Combining appropriately the basic equations, together with the fractionalized Maxwell fluid model allow us to determine the velocity, temperature and concentration of blood flow through bifurcated artery. The study adopted the Atangana-Baleanu fractional time derivative on fluid model to describe the non-Newtonian behavior of blood flow. The numerical simulations were performed using the combined Laplace transform and the method of undetermined coefficients and the results obtained with the aid of Mathcad software were simulated and presented graphically. From the graphical results, …


Does Volume Cycling Elicit A Skeletal Muscle Hypertrophy Re-Sensitization Effect? A Comparison Of Constant Versus Cycled Resistance Training Protocols, Joshua C. Pelland Apr 2026

Does Volume Cycling Elicit A Skeletal Muscle Hypertrophy Re-Sensitization Effect? A Comparison Of Constant Versus Cycled Resistance Training Protocols, Joshua C. Pelland

Electronic Theses and Dissertations

Purpose: This study examined whether volume cycling in resistance training can elicit a skeletal muscle hypertrophy re-sensitization effect without muscle atrophy. We hypothesized that muscle size would be maintained during lower volume phases, that re-sensitization would occur following these phases, and that overall hypertrophy would be similar between cycled and constant volume conditions.

Methods: Thirty-seven trained men and women had their lower limbs randomized to either a constant volume (12 sets/week throughout) or cycled volume (alternating 4-week phases of 12 and 4 sets/week) condition for unilateral calf press training over 20 weeks. Lateral and medial gastrocnemius muscle thickness (MT), calf …


Diabetes Mellitus And Its Association With Tuberculosis Clinical Presentation And Treatment Outcomes: Results From A Prospective Cohort Study In Ghana, Monica Baaba Jones, Kwadwo Ansah Koram, Francis Anto, Michael Lauzardo, Blanca I. Restrepo, Margaret Lartey, Hafisatu Gbadamosi, Awewura Kwara Apr 2026

Diabetes Mellitus And Its Association With Tuberculosis Clinical Presentation And Treatment Outcomes: Results From A Prospective Cohort Study In Ghana, Monica Baaba Jones, Kwadwo Ansah Koram, Francis Anto, Michael Lauzardo, Blanca I. Restrepo, Margaret Lartey, Hafisatu Gbadamosi, Awewura Kwara

School of Medicine Publications

Background: Tuberculosis (TB)-diabetes is a growing public health threat in TB-endemic settings. We aimed to determine diabetes prevalence among TB patients in Greater Accra and its association with TB clinical presentation and treatment outcomes.

Methods: We enrolled 204 adults (≥20 years) with bacteriologically confirmed pulmonary TB across 14 health facilities. At treatment initiation, participants were screened for diabetes using self-report, fasting plasma glucose, and glycated hemoglobin, following standard diagnostic criteria. Baseline characteristics were recorded, and participants were followed to determine TB treatment outcomes. Associations between diabetes, baseline characteristics and treatment outcomes were assessed using bivariate and multivariate analysis in STATA. …


Preparation And Characterization Of Double-Network Composite Hydrogels With Carboxymethyl Pachymaran In Promoting Wound Healing, Haodong Wu, Xi Feng, Zhinan Mei, Wen Huang, Ying Liu Apr 2026

Preparation And Characterization Of Double-Network Composite Hydrogels With Carboxymethyl Pachymaran In Promoting Wound Healing, Haodong Wu, Xi Feng, Zhinan Mei, Wen Huang, Ying Liu

Faculty Research, Scholarly, and Creative Activity

Utilizing food-derived bioactive polysaccharides in advanced biomedical applications offers significant potential. To effectively harness the inherent bioactivity of Poria cocos, a renowned edible and medicinal fungus, we developed a multifunctional double-network composite hydrogel (CPS) via a feasible one-pot strategy. This was achieved by incorporating functional carboxymethyl pachymaran (CMP) into a matrix of food-grade sodium alginate (SA) and polyacrylamide (PAM). This formulation endows the hydrogel with excellent extensibility, rapid self-healing capabilities, and strong tissue adhesion, all while preserving the biological activity of the natural macromolecules. In a mouse full-thickness skin defect model, the CPS significantly accelerated wound recovery, achieving a healing …


The Minutes Of The Marshall University Board Of Governors Meeting, April 08, 2026, Marshall University Board Of Governors Apr 2026

The Minutes Of The Marshall University Board Of Governors Meeting, April 08, 2026, Marshall University Board Of Governors

Board of Governors Minutes

No abstract provided.


Relationship Between Hepatitis B Virus Screening, Vaccination, And Spread In Sierra Leone, Muhammed Sarmodu Mansaray Apr 2026

Relationship Between Hepatitis B Virus Screening, Vaccination, And Spread In Sierra Leone, Muhammed Sarmodu Mansaray

Walden Dissertations and Doctoral Studies

Hepatitis B virus (HBV) presents a significant public health burden in Sierra Leone. Although the estimated prevalence was 8.7% in 2021, comprehensive statistical data has been limited in general. Programmatic interventions for HBV control such as systematic screening and vaccination have remained limited as well. The purpose of this quantitative cross-sectional study was to examine the relationship between screening and vaccination practices and HBV prevalence in Sierra Leone while controlling for age, sex, education and health care access. The theoretical framework incorporated the Integrated Screening Action model, which highlights screening as a critical disease prevention strategy, and the Social Ecological …


Bone Marrow Aspirate Concentrate And Xenograft Versus Autograft And Xenograft In The 3d Reconstruction Of Atrophic Maxillary Ridges: A Split-Mouth Randomized Controlled Trial, Moataz Bahaa, Ahmed Abdelmaksoud Dr., Mohamed Mounir Prof, Yasmin Nassar Prof, Mohamed Shawky Dr., Sara Elmoshy Dr. Apr 2026

Bone Marrow Aspirate Concentrate And Xenograft Versus Autograft And Xenograft In The 3d Reconstruction Of Atrophic Maxillary Ridges: A Split-Mouth Randomized Controlled Trial, Moataz Bahaa, Ahmed Abdelmaksoud Dr., Mohamed Mounir Prof, Yasmin Nassar Prof, Mohamed Shawky Dr., Sara Elmoshy Dr.

Dentistry

To evaluate bone quality and quantity after 3D augmentation of vertically and horizontally atrophied maxillary ridges and compare the use of bone marrow aspirate concentrate (BMAC) and xenograft versus autograft and xenograft, both using prebent titanium (Ti) mesh over a virtually augmented model. Materials and Methods: Ten fully edentulous patients with severe maxillary vertical and horizontal bone loss were recruited. Virtual horizontal and vertical bone augmentation was performed for the deficient ridge to produce virtually augmented models for prebent Ti meshes preoperatively. Each patient was rehabilitated with BMAC and xenograft on one side of their mouth (test side) and with …


Association Between Childhood Exposure To Family Substance Abuse, Mental Health Issues, And Cervical Screening Among Women Ages 18-65 In South Carolina, Ashley Laine Hamm Apr 2026

Association Between Childhood Exposure To Family Substance Abuse, Mental Health Issues, And Cervical Screening Among Women Ages 18-65 In South Carolina, Ashley Laine Hamm

Walden Dissertations and Doctoral Studies

Adverse childhood experiences (ACEs) have been associated with adverse health outcomes in adulthood; however, less is known about their relationship with preventive health behaviors such as cervical cancer screening. The purpose of this quantitative, correlational study was to examine associations between selected ACEs and cervical cancer screening among women aged 18–65 in South Carolina. Data were drawn from the 2020 South Carolina Behavioral Risk Factor Surveillance System (BRFSS) and included 1,323 women. Binary logistic regression analyses were used to examine unadjusted and adjusted associations between ACE exposures and being up to date with Pap testing, controlling for age, race/ethnicity, income, …


Sociodemographic Factors And Dating Violence Among Adolescents Living In Rural Southern U.S. Communities, Kiara Patricia Sims-Thrasher Apr 2026

Sociodemographic Factors And Dating Violence Among Adolescents Living In Rural Southern U.S. Communities, Kiara Patricia Sims-Thrasher

Walden Dissertations and Doctoral Studies

Adolescent dating violence (ADV) is a significant public health issue that disproportionately affects youths in southern rural communities, yet these populations remain underrepresented in research. The purpose of this quantitative cross-sectional study was to examine the association between ADV and sociodemographic factors (gender, race, age, and education level), alcohol consumption, and bullying among adolescents in Alabama, Arkansas, and Mississippi using data from the 2021 Youth Risk Behavior Surveillance System. Guided by the social-ecological model, binary logistic regression analyses were conducted to assess relationships between ADV victimization and the selected predictors. Results indicated that females had significantly higher odds of reporting …


Clingen Api Platform For Classification Of Human Genetic Variants, Neethu Shah, Tierra Farris, Arturo Alejandro Zuniga, Andrew R Jackson, Jessie Arce, Kevin Riehle, Christine G Preston, Mark E Mandell, Bryan Wulf, Gloria Cheung, Keyang Yu, Deborah I Ritter, Dubravka Jevtic, Miroslav Milinkov, Novak Martinovic, Nevena Vucinic, Aleksandar Mihajlovic, Alan F Rubin, Melissa S Cline, Marina Distefano, Malachi Griffith, Obi L Griffith, Matt W Wright, Teri E Klein, Sharon E Plon, Aleksandar Milosavljevic Apr 2026

Clingen Api Platform For Classification Of Human Genetic Variants, Neethu Shah, Tierra Farris, Arturo Alejandro Zuniga, Andrew R Jackson, Jessie Arce, Kevin Riehle, Christine G Preston, Mark E Mandell, Bryan Wulf, Gloria Cheung, Keyang Yu, Deborah I Ritter, Dubravka Jevtic, Miroslav Milinkov, Novak Martinovic, Nevena Vucinic, Aleksandar Mihajlovic, Alan F Rubin, Melissa S Cline, Marina Distefano, Malachi Griffith, Obi L Griffith, Matt W Wright, Teri E Klein, Sharon E Plon, Aleksandar Milosavljevic

Faculty, Staff and Students Publications

In this commentary, we describe how the Clinical Genome Resource's (ClinGen's) application programming interface-based microservices accelerate growth and dissemination of knowledge about human genetic variation. By exposing findable, accessible, interoperable, reusable, and AI-ready variant data, ClinGen lays a foundation for next-generation software applications, AI systems, and variant classification workflows.


Multi-Trait Polygenic Scores For Copd And Copd Exacerbations Implicate Druggable Proteins, Chengyue Zhang, Iain R Konigsberg, Yixuan He, Jingzhou Zhang, Tinashe Chikowore, William B Feldman, Xiaowei Hu, Yi Ding, Bogdan Pasaniuc, Diana Chang, Qingwen Chen, Jessica A Lasky-Su, Julian Hecker, Martin D Tobin, Jing Chen, Sean Kalra, Katherine A Pratte, Hae Kyung Im, Emily S Wan, Ani Manichaikul, Edwin K Silverman, Russell P Bowler, Leslie A Lange, Victor E Ortega, Alicia R Martin, Michael H Cho, Matthew R Moll Apr 2026

Multi-Trait Polygenic Scores For Copd And Copd Exacerbations Implicate Druggable Proteins, Chengyue Zhang, Iain R Konigsberg, Yixuan He, Jingzhou Zhang, Tinashe Chikowore, William B Feldman, Xiaowei Hu, Yi Ding, Bogdan Pasaniuc, Diana Chang, Qingwen Chen, Jessica A Lasky-Su, Julian Hecker, Martin D Tobin, Jing Chen, Sean Kalra, Katherine A Pratte, Hae Kyung Im, Emily S Wan, Ani Manichaikul, Edwin K Silverman, Russell P Bowler, Leslie A Lange, Victor E Ortega, Alicia R Martin, Michael H Cho, Matthew R Moll

Faculty, Staff and Student Publications

BACKGROUND

We constructed multi-trait polygenic risk scores (PRSs) predicting chronic obstructive pulmonary disease (COPD) and exacerbations, validated their performance in diverse cohorts, and identified PRS-related proteins for potential therapeutic targeting.

METHODS

PRSmix+, a multi-trait PRS framework, is used to train a composite PRS (PRSmulti) in COPDGene non-Hispanic White participants (n = 6,647). Associations of PRSmulti with COPD status (GOLD 2–4 vs. GOLD 0 or ICD) and exacerbation frequency were tested in COPDGene African American (n = 2,466), ECLIPSE (n = 1,858), Mass General Brigham Biobank (n = 15,152), and All of Us (n = 118,566). …


Characterization Of Subclonal Variants In Hg002 Genome In A Bottle Reference Material As A Resource For Benchmarking Variant Callers., Camille A. Daniels, Adetola A. Abdulkadir, Megan H. Cleveland, Jennifer H. Mcdaniel, David Jáspez, Luis Alberto Rubio-Rodríguez, Adrián Muñoz-Barrera, José Miguel Lorenzo-Salazar, Carlos Flores, Byunggil Yoo, Sayed Mohammad Ebrahim Sahraeian, Yina Wang, Massimiliano Rossi, Arun Visvanath, Lisa Murray, Wei-Ting Chen, Severine Catreux, James Han, Rami Mehio, Gavin Parnaby, Andrew Carroll, Pi-Chuan Chang, Kishwar Shafin, Daniel Cook, Alexey Kolesnikov, Lucas Brambrink, Mohammed Faizal Eeman Mootor, Yash Patel, Takafumi N. Yamaguchi, Paul C. Boutros, Karolina Sienkiewicz, Jonathan Foox, Christopher E. Mason, Bryan R. Lajoie, Carlos A. Ruiz-Perez, Semyon Kruglyak, Justin M. Zook, Nathan D. Olson Apr 2026

Characterization Of Subclonal Variants In Hg002 Genome In A Bottle Reference Material As A Resource For Benchmarking Variant Callers., Camille A. Daniels, Adetola A. Abdulkadir, Megan H. Cleveland, Jennifer H. Mcdaniel, David Jáspez, Luis Alberto Rubio-Rodríguez, Adrián Muñoz-Barrera, José Miguel Lorenzo-Salazar, Carlos Flores, Byunggil Yoo, Sayed Mohammad Ebrahim Sahraeian, Yina Wang, Massimiliano Rossi, Arun Visvanath, Lisa Murray, Wei-Ting Chen, Severine Catreux, James Han, Rami Mehio, Gavin Parnaby, Andrew Carroll, Pi-Chuan Chang, Kishwar Shafin, Daniel Cook, Alexey Kolesnikov, Lucas Brambrink, Mohammed Faizal Eeman Mootor, Yash Patel, Takafumi N. Yamaguchi, Paul C. Boutros, Karolina Sienkiewicz, Jonathan Foox, Christopher E. Mason, Bryan R. Lajoie, Carlos A. Ruiz-Perez, Semyon Kruglyak, Justin M. Zook, Nathan D. Olson

Manuscripts, Articles, Book Chapters and Other Papers

We developed a benchmark set of subclonal variants in the Genome in a Bottle (GIAB) Consortium HG002 reference material (RM) DNA for evaluating lower-frequency variant callsets. We used a somatic variant caller with high-coverage (300×) whole-genome sequencing data from the GIAB Ashkenazi Jewish trio to identify potential subclonal variants in the HG002 RM DNA. Using orthogonal sequencing data and manual curation, we defined a benchmark set with 85 high-confidence subclonal single-nucleotide variants (SNVs) (allele frequency [AF] > 5%) and a benchmark region covering 2.45 Gbp of the autosomes. External validation supported that it can be used to reliably identify both false …


The Clinical And Operational Value Of Early Comprehensive Ngs In Non-Small Cell Lung Cancer, Yunus Emre Demirhan, Marcus Yoakam, Adam Soltani, Arshdeep Gill, Samir Dalia Apr 2026

The Clinical And Operational Value Of Early Comprehensive Ngs In Non-Small Cell Lung Cancer, Yunus Emre Demirhan, Marcus Yoakam, Adam Soltani, Arshdeep Gill, Samir Dalia

Student Publications

Lung cancer remains the leading cause of cancer-related mortality worldwide, and non-small cell lung cancer (NSCLC) accounts for most cases. Advances in targeted therapies and immunotherapy have improved outcomes, but their benefit depends on timely molecular characterization. Early next-generation sequencing (NGS), performed at or near diagnosis, is increasingly used to identify actionable alterations and inform first-line and perioperative treatment planning. In this review, we examine the clinical, operational, and economic rationale for early comprehensive NGS in NSCLC. Upfront sequencing can improve diagnostic yield, preserve limited tissue, reduce turnaround time, and help avoid non-matched systemic therapy. Practical implementation strategies include Molecular …


Long-Term Assessment Of Cattail (Typha Spp.) Dynamics And Wetland Restoration In The Everglades Using Object-Based Landsat Time Series And Markov Modeling, Gideon Tandoh, Stephen Yankyera, Michael Sean Chenoweth Apr 2026

Long-Term Assessment Of Cattail (Typha Spp.) Dynamics And Wetland Restoration In The Everglades Using Object-Based Landsat Time Series And Markov Modeling, Gideon Tandoh, Stephen Yankyera, Michael Sean Chenoweth

Research, Publications & Creative Work

Assessing long-term vegetation response to restoration requires spatially consistent monitoring approaches that capture both observed change and likely future trajectories. In the Florida Everglades, nutrient enrichment contributed to the expansion of cattail (Typha spp.) within Water Conservation Area 3A (WCA-3A), raising concerns about restoration effectiveness. This study integrates a multi-temporal Landsat time series (2004–2024), object-based image analysis (OBIA), support vector machine (SVM) classification, and Markov transition modeling to quantify and project vegetation change in WCA-3A. Object-based segmentation reduced classification fragmentation in heterogeneous marsh landscapes, while SVM improved separation among spectrally similar vegetation classes. Classification accuracies remained consistently high across sensors …


An Artificial Intelligence Optimized Hepatic Differentiation Unveils Nr5a2 And Ap-1 Transcriptional Regulation In Hepatic Maturation, Zijun Huo, Jian Tu, Wei-Lei Yang, Mo-Fan Huang, Ruoyu Wang, Chih-Wei Chu, An Xu, Yao Yu, Tara N Tavakol, Mikal Kizilbash, Megan E Fisher, Yu-Wen Huang, Dandan Zhu, Trinh T T Phan, Rachel Shoemaker, Ya-Wen Chen, Yang Zhang, Chad D Huff, Shih-Yu Chen, Tien-Jen Liu, Haipeng Xiao, Dung-Fang Lee, Ruiying Zhao Apr 2026

An Artificial Intelligence Optimized Hepatic Differentiation Unveils Nr5a2 And Ap-1 Transcriptional Regulation In Hepatic Maturation, Zijun Huo, Jian Tu, Wei-Lei Yang, Mo-Fan Huang, Ruoyu Wang, Chih-Wei Chu, An Xu, Yao Yu, Tara N Tavakol, Mikal Kizilbash, Megan E Fisher, Yu-Wen Huang, Dandan Zhu, Trinh T T Phan, Rachel Shoemaker, Ya-Wen Chen, Yang Zhang, Chad D Huff, Shih-Yu Chen, Tien-Jen Liu, Haipeng Xiao, Dung-Fang Lee, Ruiying Zhao

Faculty, Staff and Student Publications

The generation of hepatocyte-like cells (HLCs) from human pluripotent stem cells (hPSCs) holds great promise for drug discovery and cell-based therapy for liver disease. However, current differentiation protocols are complicated and unstable, and the underlying gene regulatory mechanisms of hepatic differentiation remain incompletely defined. Here, we developed a machine learning-based artificial intelligence (AI) tool using phase-contrast images of hepatic progenitor cells (HPCs), which are essential for generating HLCs. The AI tool significantly improves the success rate of hepatic differentiation without the need for immunostaining or lineage tracing. By optimizing the methodology, we achieved an impressive purity of 90-95% for HLCs …


The Effects Of Orexin Receptor Antagonism During Early Withdrawal In Stimulant Use Disorder: Protocol For A Proof-Of-Concept Study, Heather Webber, Nikky Tran, Rita Blake, Sarah Goldman, Trevor George, Bill Bailey, Robert Suchting, Jin Yoon, Jessica Vincent, Michael Weaver, Joy Schmitz, Scott Lane Apr 2026

The Effects Of Orexin Receptor Antagonism During Early Withdrawal In Stimulant Use Disorder: Protocol For A Proof-Of-Concept Study, Heather Webber, Nikky Tran, Rita Blake, Sarah Goldman, Trevor George, Bill Bailey, Robert Suchting, Jin Yoon, Jessica Vincent, Michael Weaver, Joy Schmitz, Scott Lane

Faculty, Staff and Student Publications

Background: Stimulant use disorders (StimUDs), including cocaine and methamphetamine use disorders, remain a major public health concern in the United States with no US Food and Drug Administration (FDA)-approved pharmacological treatments. The early recovery period following stimulant use is marked by sleep disturbances, heightened stress reactivity, and dysregulated reward processing, contributing to high rates of resumption of use. Evidence from animal and human studies supports the orexin neuropeptide system as a promising therapeutic target for minimizing these disruptive mechanisms. Suvorexant, an FDA-approved dual orexin receptor antagonist for insomnia, has previously been shown to improve sleep, reduce stress, and attenuate craving …


Spartan Daily, April 8, 2026, San Jose State University, School Of Journalism And Mass Communications Apr 2026

Spartan Daily, April 8, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 30


What Are The Top 10 Global Research Priorities For Perianal Crohn's Disease? The Global Perianal Crohn's Disease Priority Setting Partnership, Theo Pelly, Parakkal Deepak, Et Al. Apr 2026

What Are The Top 10 Global Research Priorities For Perianal Crohn's Disease? The Global Perianal Crohn's Disease Priority Setting Partnership, Theo Pelly, Parakkal Deepak, Et Al.

2020-Current year OA Pubs

BACKGROUND AND AIMS: Perianal Crohn's disease (pCD) is a debilitating condition with a prevalence of approximately 20% in patients within 10 years of diagnosis of CD. The condition significantly impacts patient quality of life, and there remain a number of unmet needs relating to its optimal management. A global Priority Setting Partnership (PSP) was established to identify the top 10 research priorities for pCD.

METHODS: The PSP followed standard James Lind Alliance (JLA) methodology. An initial survey was circulated to gather unanswered research questions from key stakeholders. From these responses, a longlist of summary questions was formed. These questions were …


Opening Closed Doors: Supporting Undergraduate Scholars Through Open-Access Publishing, Amelia Baker, Kiara O'Neal, Mikkel Cullen, Amy Buddie, Haleigh Edmonds Apr 2026

Opening Closed Doors: Supporting Undergraduate Scholars Through Open-Access Publishing, Amelia Baker, Kiara O'Neal, Mikkel Cullen, Amy Buddie, Haleigh Edmonds

All Things Open

Undergraduate publishing is often a closed door due to paywalls, publication fees, and limited access to mentorship. The Kennesaw Journal of Undergraduate Research (KJUR) uses an open-access framework to remove these barriers and expand equitable access to scholarly publishing for students at Kennesaw State University. KJUR is free to submit to and publish in, ensuring financial constraints do not prevent students from sharing their work. The journal is operated by paid and volunteer student editors, providing mentored, hands-on experience in academic publishing. Emphasizing open pedagogy, KJUR supports student authors through developmental editing and multi-semester collaboration, guiding them through …


The Shorthorn: December 5, 1980 Apr 2026

The Shorthorn: December 5, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: December 3, 1980 Apr 2026

The Shorthorn: December 3, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.