Digital Commons Network^™

The Presence And Distribution Of Crotoxin In The Rock Rattlesnake (Crotalus Lepidus), Jade Mellor

All Theses

Crotoxin and its homologs (hereafter all referred to as CTx) is a highly lethal heterodimeric beta-neurotoxin found in pitvipers (Crotalinae) and is the main driver of neurotoxic venom phenotypes (Type II). In contrast, hemorrhagic venom phenotypes (Type I) are characterized by high snake venom metalloproteinase expression and low toxicity. Although many rattlesnake species have been classified as either Type I or Type II, population level variation in venom phenotype has also been documented in several species. The presence or absence of CTx is the main component of this variation in venom phenotype and has been most widely studied in large-bodied …

“I Held On At Any Price”: Victim Self-Preservation In The Sonderkommando In Auschwitz And Treblinka, Jessica Christina Foster

All Theses

Many Holocaust victims have expressed uneasiness or even shame regarding the actions they took to stay alive in the death camps. These acts of self-preservation were usually humiliating and often came at the expense of their fellow victims. This comes out most clearly in the testimonies of the members of the Sonderkommando in Auschwitz and Treblinka. Writers such as Filip Müller, Zalmen Gradowski, and Richard Glazar recount how they survived the lethal environment of the camp by appropriating the food, clothing, and valuables of the people murdered in the gas chambers. Although most scholars have interpreted these testimonies, and the …

Chandra Ejecta Kinematics Studies And An Iso Spectroscopic Survey Of Supernova Remnants, Matthew James Millard

Physics Dissertations - Archive

The structure of metal-rich ejecta created from a supernova (SN) reveals vital information about the explosion of the progenitor star and the dynamical evolution of the supernova remnant (SNR). This research focuses on the ejecta kinematics of SNRs in two projects. In the first project, we use High Energy Transmission Grating (HETG) spectroscopy and archival Advanced CCD Imaging Spectrometer (ACIS) imaging from the Chandra X-ray Observatory to study the 3-D ejecta structure of the remnants of the historical Type Ia SNe, SN 1572 (Tycho’s SNR) and SN 1604 (Kepler’s SNR). We use our 150 ks high-resolution Chandra HETG spectroscopic observation …

A Bioinformatics Analysis Of Microbial Diversity And Its Correlation With Human Lifestyle, Diet, And Health Variables, Alivia Ankrum, Kate Cooper

Theses/Capstones/Creative Projects

The abundant impact of microbiota on human physiology suggests a need for exploration into their impact on human health and disease. The American Gut Project (AGP) was established to aggregate microbiome sequencing data as well as health, diet, and lifestyle metadata. This study proposes to identify taxonomic species and build a phylogenetic tree representation from the AGP participant sample collection as well as find their respective alpha and beta diversity of all metadata variables based on patient questionnaire data. Additionally, this study will involve a chimeric sequence extraction from the 16S rRNA sequences of the AGP. The expected results are …

The Nciter Newsletter: August 2022, National Counterterrorism Innovation, Technology, And Education Center

Newsletters

NCITE (National Counterterrorism Innovation, Technology, and Education) is the Department of Homeland Security's center of excellence for terrorism prevention and counterterrorism research. They are a federally funded academic consortium based in Omaha, Nebraska. Their newsletters covers the current news, activities, and updates of the center and the latest in counterterrorism research. NCITEr newsletter covers specifically center updates.

Genome Architecture And Diverged Selection Shaping Pattern Of Genomic Differentiation In Wild Barley, Wenying Zhang, Cong Tan, Haifei Hu, Rui Pan, Yuhui Xiao, Kai Ouyang, Gaofeng Zhou, Yong Jia, Xiao-Qi Zhang, Camilla Beate Hill, Penghao Wang, Brett Chapman, Yong Han, Le Xu, Yanhao Xu, Tefera Angessa, Hao Luo, Sharon Westcott, Darshan Sharma, Eviatar Nevo, Roberto A. Barrero, Matthew I. Bellgard, Tianhua He, Xiaohai Tian, Chengdao Li

Grain and Other Field Crops Research Articles

Summary

Divergent selection of populations in contrasting environments leads to functional genomic divergence. However, the genomic architecture underlying heterogeneous genomic differentiation remains poorly understood. Here, we de novo assembled two high-quality wild barley (Hordeum spontaneum K. Koch) genomes and examined genomic differentiation andgene expression patterns under abiotic stress in two populations. These two populations had a shared ancestry and originated in close geographic proximity but experienced different selective pressures due to their contrasting micro-environments. We identified structural variants that may have played significant roles in affecting genes potentially associated with well-differentiated phenotypes such as flowering time and drought response between …

Higher-Order Nonstandard Finite Difference Methods For Autonomous Differential Equations With Applications In Mathematical Ecology, Fawaz Karhan R Alalhareth

Mathematics Dissertations - Archive

Nonstandard finite difference (NSFD) methods have been widely used to numerically solve various problems in biology. In recent years, NSFD methods have been proposed that preserve essential properties of the solutions of general autonomous differential equations, such as positivity and elementary stability, among others. However, those methods are only of first-order accuracy. In the first part of this dissertation, we construct and analyze two second-order modified positive and elementary stable nonstandard (PESN) numerical methods for n-dimensional autonomous differential equations. The new PESN methods are generalized versions of the explicit Euler's method and second-order accurate, thereby improving the order of accuracy …

Using Portable X-Ray Fluorescence To Predict Physical And Chemical Properties Of California Soils, Micaela D. Frye

Master's Theses

Soil characterization provides the basic information necessary for understanding the physical, chemical, and biological properties of soils. Knowledge about soils can in turn be used to inform management practices, optimize agricultural operations, and ensure the continuation of ecosystem services provided by soils. However, current analytical standards for identifying each distinct property are costly and time-consuming. The optimization of laboratory grade technology for wide scale use is demonstrated by advances in a proximal soil sensing technique known as portable X-ray fluorescence spectrometry (pXRF). pXRF analyzers use high energy Xrays that interact with a sample to cause characteristic reflorescence that can be …

Weight Maintenance, A Prognostic Factor That Mediates The Incidence Of Dementia: From Genetics To Etiologies, Sunny Chen

All Dissertations

Objectives: Alzheimer’s disease-related dementia is a devastating neurodegenerative disease that affects millions of people. The goal of this work is to investigate biological mechanisms such as weight loss and mitochondrial function that can serve as prognostic factors for dementia, healthy aging, and longevity.

Methodologies: This work consists of two separate systematic literature reviews, and an investigational study. The first review examined existing studies on weight trends in dementia. The second review investigated the role of mitochondria and its associated gene TOMM40 in aging. The third paper included a nested case control analysis of weight change patterns before and …

3d Printed Multicomponent Polymer Based Materials Via Hybrid Filaments: Fabrication And Characterization, Erik Antonio

All Dissertations

Additive manufacturing, also known as 3D printing, promises a manufacturing revolution for both industry and academic circles. One of the most widely used method of 3D printing is Fused Deposition Modeling (FDM) or Fused Filament Fabrication (FFF), which requires a thermoplastic filament to be directed towards a heating block and then deposited via extrusion layer by layer to produce a finished part. However, there are significant issues with this technology, mainly a limitation on the materials available for use and mechanical property deficiencies when compared to traditional manufacturing. These issues are brought about by the temperature limited nature of the …

Fanwork Communication Through Social Media: A Dynamic Practice Of Celebrity Fans In China, Qiuyan Guo

Proceedings from the Document Academy

Contemporary Chinese celebrity fans mainly engage in two innovative types of fanwork communications through social media: 1) digital relays of sequentially creating and presenting their own complete fan art and fiction and 2) dissemination of fan-made non-digital peripheral materials by mail or in person after online showcasing. Based on unobtrusive observation and semi-structured interviews, this paper presents the specific steps in both types of communication activities among fans of two Chinese musical actors, Ayanga and Yunlong, on the Weibo platform. Exceeding fans’ traditional sole emphasis on cataloging their creations, these fanwork communications comprise the information creation (organization), dissemination, and preservation …

Addams’S Methodologies Of Writing, Thinking, And Activism, Marilyn Fischer

Books and Book Chapters by University of Dayton Faculty

To understand Addams’s texts, readers need to attend both to her evolutionary methodologies and to her interpretive strategies. Addams was an evolutionary scientist and sociologist in the days before natural selection became merged with genetics and before sociology adopted a stance of positivistic objectivity. Like other intellectuals at the nineteenth century’s turn, Addams addressed contemporary social problems by locating them within their evolutionary histories and proposing ways of moving society toward healthy equilibrium. She used specific social theories as tools, selecting the ones best suited for each given social problem. Evolutionary theorizing served as foundation and framing for her writings. …

Climate Science In Adaptation Litigation In The U.S., Jacob Elkin

Sabin Center for Climate Change Law

The most prominent climate litigation to date has primarily focused on mitigation—reducing greenhouse gas emissions—but as climate impacts become more frequent, extreme, and intense, adaptation litigation will increase. Adaptation cases frequently rely on evidence drawn from scientific research into past and future climate change. This research oftentimes consists of one of two types of climate research: attribution studies of climate change to date, and future projections of climate change and its impacts.

Climate change attribution links human activity to climate change, especially changes in the statistics of extreme weather events. Increasingly, it is also beginning to be applied to impacts …

Validation Of Whole Genome Resequencing For Mapping The Genetics Of Ascites In Broilers And Viral Susceptibility In Layers, Katherine Pepper Lee

Graduate Theses and Dissertations

This dissertation focused on the efficacy and validity of whole genome resequencing (WGR) for fine mapping genetic determinants of particular traits in a given organism. Previously, our research group used WGR to identify haplotype blocks of single nucleotide polymorphisms associated with ascites resistance with some as strong candidates for use in marker-assisted selection (MAS). Chapter 2 discusses the completion of a MAS project through evaluation of ascites incidence as well as production traits of economic value to poultry producers. Thus, the MAS project also covered viability of this methodology in the industry. The MAS significantly reduced ascites incidence in broilers …

Mild-Condition Fractionation Of Woody Biomass And Tandem Preservation Of Lignin And Carbohydrates, Danni Xie

Dissertations

Various fractionation processes like kraft, sulfite, and organosolv, usually need to be carried out in expensive reactors due to high temperatures (e.g., 160-260 °C) and high pressures (e.g., 5-50 atm). During fractionation, conventional chemicals such as mineral acids (e.g., sulfonic acid and hydrochloric acid), aliphatic organic acids (e.g., formic acid and oxalic acid) and alkalis (e.g., sodium hydroxide and potassium hydroxide) are typically used as catalysts, which could cause structural alterations or even losses to the fractionated components. Recently, aromatic sulfonic acids are expected to in situ solubilize the fractionated lignin through the pronounced hydrotropic effect during fractionation, besides acting …

Development Of Smart Wearable Sensory Systems On Flexible And Fabric Platforms For Health Monitoring Applications, Simin Masihi

Dissertations

Wearable sensing technology has recently received an increased attention in both research and commercialization phases and has moved from a vision of science fiction to reality with a wide variety of applications. This incredible growth can be attributed to several factors, such as affordability and ergonomics provided by advances in flexible electronics. The other factors that realized wearable sensing technology include a critical need for more accessible health care services experienced during the recent COVID pandemic, integration to the Internet of Things (IoT), and a growing consumer desire for health awareness. This dissertation presents the fulfillment of three main projects …

Effects Of Ahcc On The Interaction Between T And B Lymphocytes, Sajina Poudel

Theses (2016-Present)

AHCC is a beta-glucan derived from the shiitake mushroom. It is used as an immune supplement and is known to boost the immune system. The mechanisms involved are increased lymphocyte proliferation and reduction of inflammation. The effects have been well studied in T cells. However, factors produced by T cells that affect B cells have not been studied. In this study, we explored the gene products stimulated by the AHCC exposure in T lymphocytes which play a role in B cell function. Data from a prior gene array experiment were used to delineate the effects of AHCC on the interaction …

An Overview Of The Extracurricular Polysaccaride Production Of Probiotic Lactic Acid Bacteria, Olujimi Babajide Olowokere

Theses (2016-Present)

The study focuses on a comprehensive review of lactic acid bacteria and their production of extracellular polysaccharide substrates (EPS). Two important factors are addressed in the work; and these are 1) identification of LAB stains found in the commercially sold daily milk, 2) significant factors impacting polysaccharide production. Motivation behind these focus points is to allow further inquiries and studies on exploring these strains of bacteria for human wellness promotion. With microbial EPS production being a recent interest of study among healthcare and food industries sectors, new species of bacteria are extensively exploited for further investigation to improve human health, …

Screening Tcf19 And Kif18b To Determine Co-Regulation With Mybl1 In Triple Negative Breast Cancer Patient Tissues, Tyra Sharda Ivory

Theses (2016-Present)

The aggressive behavior in triple-negative breast cancer (TNBC) is due to genetic signaling events, which call for the comprehensive analyses of genes differentially regulated in the cancers. Our laboratory previously found that MYBL1 was over-expressed in a fraction of the TNBC, compared to some luminal, and other breast cancer subtypes. The MYBL1 gene is a proto-oncogene that serves as a strong transcriptional activator. The gene is involved in signaling events related to cell cycle signaling, differentiation, proliferation, and apoptosis, all which are differentially regulated in cancers. Because MYBL1 is a transcription regulator, involved in cancer-related mechanisms and differentially expressed in …

Hsp- 70 Mediated Nervous System Enhancement By Etas, Taylor Carter

Theses (2016-Present)

Neurodegenerative disease in the CNS is usually a product of increased oxidative stress in the brain. In this study we tested the ability of an asparagus supplement ETAS to help reduce oxidative stress in the normal brains of Balb C mice. Oxidative stress pathways (Heat shock proteins) are usually cumulative in the damage they cause when disrupted. We treated normal Balb C mice with ETAS and had control groups with no ETAS supplementation in their regular diet. We then sacrificed the mice and conducted microarray studies to compare oxidative stress pathway genes. We also characterized the effects of regular oxidative …

Tau-Dependent Neurodegeneration And Alleviation By Etas®50, Clifford Tyree Castleberry

Theses (2016-Present)

Brain growth factors are a broad group of molecules that enable the brain to adapt to stress. In a study on Alzheimer’s mice (APP), we tested the role of an asparagus supplement, ETAS®50, to mitigate the stress caused by the Alzheimer’s condition in this mouse model. Gene expression data revealed regulation of genes related to neuronal growth and function, such as tau, which were severely stressed in the APP mice to be alleviated.

B.R. Wells Arkansas Rice Research Studies 2021, J. Hardke, X. Sha, N. Bateman

Arkansas Agricultural Experiment Station Research Series

Arkansas is the leading rice producer in the United States. The state represents 47.5% of total U.S. rice production and 47.8% of the total acres planted to rice in 2021. Rice cultural practices vary across the state and across the U.S. However, these practices are also dynamic and continue to evolve in response to changing political, environmental, and economic times. This survey was initiated in 2002 to monitor and record changes in the way Arkansas rice producers approach their livelihood. The survey was conducted by polling county extension agents in each of the counties in Arkansas that produce rice. Questions …

Microbiological, Environmental, And Compositional Factors In Efficacy Of Micp Treatment In Clayey Soils, Somaye Asghari

Boise State University Theses and Dissertations

Expansive clayey soils can cause billions of dollars of damage to infrastructure such as roads and foundations annually. Researchers propose many techniques (e.g., pre-wetting, soil replacement, and chemical stabilization) to improve the mechanical properties of these soils; however, some of these methods are impractical in certain situations, and are unsustainable in others due to the economic and environmental impacts. One possible method for enhancing soil’s mechanical properties is Microbial Induced Calcium Carbonate Precipitation (MICP). This environmentally friendly technique is a biological process where microbes play a key role in precipitating calcium carbonate. This precipitating calcium carbonate can coat soil particles …

Characterizing Wildfire In The Frank Church Wilderness, Idaho, Between 1972-2012, Abigail Christine Axness

Boise State University Theses and Dissertations

I examined wildfire characteristics in the Frank Church Wilderness, central Idaho, between 1972-2012. Studying fire characteristics in the Frank Church Wilderness provides an opportunity to understand the history of wildfires in a federally designated wilderness area, largely devoid of management impacts with limited human access and activity. The ~958,000-hectare Frank Church Wilderness area encompasses the Middle Fork Salmon River. Vegetation cover ranges from high elevation (~2500-3200 meters) mixed conifer forests in the headwaters to low-elevation (~600-1000 meters) sagebrush-steppe and ponderosa pine (Pinus Ponderosa) forests. The Frank Church Wilderness is defined as unmanaged because effective fire suppression (e.g., vehicle …

Petrochronology And Statistical Analysis To Integrate Different Types Of Data To Solve Complex Earth Systems Problems, Claire Ostwald Harrigan

Boise State University Theses and Dissertations

Complex Earth systems problems, like reconstructing orogens and calibrating the geologic time scale, require investigations that link time to geologic processes. To use time as a means of organizing geologic evidence, geochronometric dates must be contextualized by integrating with different data types. This is the work of petrochronology—linking mineral ages to geochemical, textural, or other geologic information. The U-Pb isotopic system as preserved in the minerals zircon (ZrSiO₄) and titanite (CaTiSiO₅) can be used in a petrochronological context to date geologic events including the age of granitoid pluton emplacement, the age of rock fabric formation in …

Disturbance, Vegetation Co-Occurrence, And Human Intervention As Drivers Of Plant Species Distributions In The Sagebrush Steppe, Fiona Claire Schaus Noonan

Boise State University Theses and Dissertations

Changes in fire regimes, invasive species dynamics, human land use, and drought conditions have shifted important plant species in the Northern Great Basin (NGB)—including big sagebrush (Artemisia tridentata ssp.), conifers (e.g., Juniperus spp.) and invasive annual grasses (e.g., Bromus tectorum). Characterizing how these overlapping disturbances influence species distributions is critical for land management decision-making. Previous research has explored the individual effects of drought, wildfire, restoration, and invasive species on sagebrush steppe communities, but the specific effects of these disturbances in context with one another remain poorly understood at a landscape scale. To address this …

From River Channel To Cloud Tops: Evaluation And Applications Of Regional Climate Models In Mountain Watersheds, William J. Rudisill

Boise State University Theses and Dissertations

Mountain ranges are vital ”water towers” of the world and are uniquely threatened by anthropogenic climate change. At the same time, the paucity of observing networks limits our understanding of hydrometeorological processes in water-resource critical regions, including the Western United States. In the past decade, non-hydrostatic, convection permitting ( 1-4km horizontal resolution) regional climate models (RCMs) have emerged as a promising tool for both reconstructing regional scale mountain hydroclimates, and for forecasting the impacts of climate perturbations on watersheds and water-resources. Still, challenges remain. To-date, computational and data storage limitations have generally precluded many RCM studies to a handful of …

Exploring Sex Differences In The Effect Of Cannabidiol On Physical Activity, Cognition, Psychological Wellbeing, And Inflammatory And Neural Health Biomarkers, Victoria Flores

Dissertations

Cannabidiol (CBD) is believed to improve physical and mental health in recreationally active men and women. The purpose of this study was to investigate the biological sex-related differences in physical activity, health-related fitness, mental and cognitive health, and biomarkers of inflammation and neural health before and after an 8-week CBD intervention. Participants (N =49; CBD Treatment Group (CG): n =24; Placebo Treatment Group (PG): n = 25; Females: n = 25; Males: n = 24; Males in CBD Group (CF-M): n = 12; Females in CBD Group (CG-F), n = 12; Males in Placebo Group (PG-M): n =12; Females in …

A Probable Case Of Osteosarcoma: A Differential Diagnosis Of Cancers In The Ancient World, Katherine A. Hosick

Honors Theses

Ongoing archaeological investigations at the North Tombs Cemetery, Tell El-Amarna, Egypt, have, to date, yielded a skeletal sample of 141 graves and at least 252 individuals that have been recovered, representing the non-elite responsible for erecting, and inhabiting a new city (c. 1353 BCE) (Dabbs, 2020) . Recent data on the recovered remains show a trend toward pathological changes in the skeletons attributable to occupational stress-related injuries, specifically those associated with demanding physical labor. One individual (Individual 1154), who was buried wrapped in textile, as is typical of the cemetery exhibited an abnormal bony abnormal bony proliferative lesion on the …

The Effect Of Post-Harvest Storage Temperature And Drying Method On The Pathogen Load Of Edible Kelp, Jessica Vorse

All Theses And Dissertations

The American seaweed industry is growing, primarily into the edible sector, and as a result, more seaweed products are available for human consumption. It is necessary to evaluate the safety of industry’s current post-harvest storage and processing methods to ensure the risk of foodborne pathogens on edible seaweed remains low. We evaluated the pathogen load of edible kelp post-harvest under three different storage temperatures (4˚C, 10˚C, 20˚C) and two different drying methods (air- and freeze-drying). The focal pathogens for this project were six of the most common food-associated pathogens in the United States: Listeria monocytogenes, Salmonella enterica, Staphylococcus aureus, pathogenic …