Digital Commons Network^™

Haaland V. Brackeen, Et Al.: Brief Of Indian Law Professors As Amici Curiae In Support Of Federal And Tribal Defendants, Matthew L.M. Fletcher

Appellate Briefs

Amici are professors and scholars of federal Indian law whose scholarship and clinical practice focus on the subject matter areas of Indian law, tribal powers, and federal- and state-court jurisdiction. Amici possess expertise in this area and an interest in ensuring that cases concerning these issues are decided consistently with the text of the United States Constitution, foundational principles in this area of law, and the express intent of Congress. Amici respectfully submit this brief to provide the Court history and context behind the Constitution’s use of Indian status classifications and the inherently political determinations that the legislative and executive …

Proteomic Profiling Platforms Head To Head: Leveraging Genetics And Clinical Traits To Compare Aptamer- And Antibody-Based Methods, Daniel H. Katz, Jeremy M. Robbins, Shuliang Deng, Usman A. Tahir, Alexander G. Bick, Akhil Pampana, Zhi Yu, Debby Ngo, Mark D. Benson, Zsu-Zsu Chen, Daniel E. Cruz, Dongxiao Shen, Yan Gao, Claude Bouchard, Mark A. Sarzynski Facsm, Adolfo Correa, Pradeep Natarajan, James G. Wilson, Robert E. Gerszten

Faculty Publications

High-throughput proteomic profiling using antibody or aptamer-based affinity reagents is used increasingly in human studies. However, direct analyses to address the relative strengths and weaknesses of these platforms are lacking. We assessed findings from the SomaScan1.3K (N = 1301 reagents), the SomaScan5K platform (N = 4979 reagents), and the Olink Explore (N = 1472 reagents) profiling techniques in 568 adults from the Jackson Heart Study and 219 participants in the HERITAGE Family Study across four performance domains: precision, accuracy, analytic breadth, and phenotypic associations leveraging detailed clinical phenotyping and genetic data. Across these studies, we show evidence …

Cmv And Ebv Co-Infection In Hiv-Infected Children: Infection Rates And Analysis Of Differential Expression Of Cytokines In Hiv Mono- And Hiv-Cmv-Ebv Co-Infected Groups, Fizza Nazim, Hammad Afzal Kayani, Aspara Ali Nathwani, Fatima Mir, Syed Hani Abidi

Department of Biological & Biomedical Sciences

Background: CMV and EBV co-infections can affect the HIV disease progression by modulating the immune system. The disease dynamics can differ in HIV-positive adults and children. In Pakistan, HIV is rapidly expanding, especially in children; however, the prevalence of CMV and EBV co-infection and the effect on immune modulation in HIV-positive children are not known. This study aimed to bridge this gap by estimating the rate of active CMV and EBV co-infection in HIV-positive children, followed by the analysis of differential expression of cytokines in HIV mono- and HIV/CMV/EBV co-infected children.
Methods: DNA samples from 319 HIV-positive children, previously recruited …

Diving Into The Vertical Dimension Of Elasmobranch Movement Ecology, Samantha Andrzejaczek, Tim C. D. Lucas, Maurice C. Goodman, Nigel E. Hussey, Amelia J. Armstrong, Aaron B. Carlisle, Daniel M. Coffey, Adrian C. Gleiss, Charlie Huveneers, David M. P. Jacoby, Mark G. Meekan, Johann Mourier, Lauren R. Peel, Katya Abrantes, Andre S. Afonso, Matthew J. Ajemian, Brooke N. Anderson, Scot D. Anderson, Gonzalo Araujo, Asia O. Armstrong, Pascal Bach, Adam Barnett, Mike B. Bennett, Natalia P. A. Bezerra, Ramon Bonfil, Andre M. Boustany, Heather D. Bowlby, Ilka Branco, Carmin D. Braun, Edward J. Brooks, Judith Brown, Patrick J. Burke, Paul Butcher, Michael Castleton, Taylor K. Chapple, Olivier Chateau, Maurice Clarke, Rui Coelho, Enric Cortes, Lydie I. E. Couturier, Paul D. Cowley, Donald A. Croll, Juan M. Cuevas, Tobey H. Curtis, Laurent Dagorn, Jonathan J. Dale, Ryan Daly, Heidi Dewar, Philip D. Doherty, Andres Domingo, Alistair D. M. Dove, Michael Drew, Christine L. Dudgeon, Clinton A. J. Duffy, Riley G. Elliott, Jim R. Ellis, Mark V. Erdmann, Thomas J. Farrugia, Luciana C. Ferreira, Francesco Ferretti, John D. Filmalter, Brittany Finucci, Chris Fischer, Richard Fitzpatrick, Fabien Forget, Kerstin Forsberg, Malcolm P. Francis, Bryan R. Franks, Austin J. Gallagher, Felipe Galva-Magana, Mirta L. Garcia, Troy F. Gaston, Bronwyn M. Gillanders, Matthew J. Gollock, Jonathan R. Green, Sofia Green, Christopher A. Griffiths, Neil Hammerschlag, Abdi Hasan, Lucy A. Hawkes, Fabio H.V. Hazin, Matthew Heard, Alex Hearn, Suzanne M. Henderson, John C. Holdsworth, Kim N. Holland, Lucy A. Howey, Robert E. Hueter, Nicolas E. Humphries, Melanie Hutchinson, Fabrice R. A. Jaine, Salvador J. Jorgensen, Paul E. Kanive, Jessica Labaja, Fernanda O. Lana, Hugo Lassauce, Rebecca S. Lipscombe, Fiona Llewellyn, Bruno C. L. Macena, Ronald Mambrasar, Jaime D. Mcallister, Sophy R. Mccully Phillips, Frazer Mcgregor, Matthew N. Mcmillan, Lianne M. Mcnaughton, Sibele A. Mendonça, Carl G. Meyer, Megan Meyers, John A. Mohan, John C. Montgomery, Gonzalo Mucientes, Michael K. Musyl, Nicole Nasby-Lucas, Lisa Natanson, John B. O'Sullivan, Paulo Oliveira, Yannis P. Papastamatiou, Toby A. Patterson, Simon J. Pierce, Nuno Queiroz, Craig A. Radford, Andy J. Richardson, Anthony J. Richardson, David Righton, Christoph A. Rohner, Mark A. Royer, Ryan A. Saunders, Matthias Schaber, Robert J. Schallert, Michael C. Scholl, Andrew C. Seitz, Jayson M. Semmens, Edy Setyawan, Brendan D. Shea, Rafid A. Shidqi, George Shillinger, Oliver N. Shipley, Mahmood Shivji, Abraham B. Sianipar, Joana F. Silva, David W. Sims, Gregory B. Skomal, Lara L. Sousa, Emily J. Southall, Julia L. Y. Spaet, Killian M. Stehfest, Guy Stevens, Joshua D. Stewart, James Sulikowski, Ismail Syakurachman, Simon R. Thorrold, Michele Thums, David Tickler, Mariana T. Tolloti, Kathy A. Townsend, Paulo Travassos, John P. Tyminski, Jeremy Vaudo, Drausio Veras, Laurent Wantiez, Sam B. Weber, R.J. David Wells, Kevin C. Weng, Bradley M. Wetherbee, Jane E. Williamson, Matthew J. Witt, Serena Wright, Kelly Zilliacus, Barbara A. Block, David J. Curnick

Marine & Environmental Sciences Faculty Articles

Knowledge of the three-dimensional movement patterns of elasmobranchs is vital to understand their ecological roles and exposure to anthropogenic pressures. To date, comparative studies among species at global scales have mostly focused on horizontal movements. Our study addresses the knowledge gap of vertical movements by compiling the first global synthesis of vertical habitat use by elasmobranchs from data obtained by deployment of 989 biotelemetry tags on 38 elasmobranch species. Elasmobranchs displayed high intra- and interspecific variability in vertical movement patterns. Substantial vertical overlap was observed for many epipelagic elasmobranchs, indicating an increased likelihood to display spatial overlap, biologically interact, and …

Human Total, Basal And Activity Energy Expenditures Are Independent Of Ambient Environmental Temperature, Xueying Zhang, Yosuke Yamada, Hiroyuki Sagayama, Philip N. Ainslie, Ellen E. Blaak, Maciej S. Buchowski, Graeme L. Close, Jamie A. Cooper, Sai Krupa Das, Lara R. Dugas, Michael Gurven, Asmaa El Hamdouchi, Sumei Hu, Noorjehan Joonas, Peter Katzmarzyk, William E. Kraus, Robert F. Kushner, William R. Leonard, Corby K. Martin, Erwin P. Meijer, Marian L. Neuhouser, Robert M. Ojiambo, Yannis P. Pitsiladis, Guy Plasqui, Ross L. Prentice, Susan B. Racette, Eric Ravussin, Leanne M. Redman, Rebecca M. Reynolds, Susan B. Roberts, Luis B. Sardinha, Analiza M. Silva, Eric Stice, Samuel S. Urlacher

Clinical Research Faculty Publications

Lower ambient temperature (Ta) requires greater energy expenditure to sustain body temperature. However, effects of Ta on human energetics may be buffered by environmental modification and behavioral compensation. We used the IAEA DLW database for adults in the USA (n = 3213) to determine the effect of Ta (−10 to +30°C) on TEE, basal (BEE) and activity energy expenditure (AEE) and physical activity level (PAL). There were no significant relationships (p > 0.05) between maximum, minimum and average Ta and TEE, BEE, AEE and PAL. After adjustment for fat-free mass, fat mass and age, statistically significant (p < 0.01) relationships between TEE, BEE and Ta emerged in females but the effect sizes were not biologically meaningful. Temperatures inside buildings are regulated at 18–25°C independent of latitude. Hence, adults in the US modify their environments to keep TEE constant across a wide range of external ambient temperatures.

Indiana Law Fertility Expert A Resource On Fraud Legislation, James Owsley Boyd

Keep Up With the Latest News from the Law School (blog)

A piece of new, bipartisan legislation that would make knowingly misrepresenting the nature or source of DNA used in assisted reproductive procedures or other fertility treatments a federal crime has a tie to the Maurer School of Law.

Jody Madeira, a nationally recognized expert on fertility fraud, bioethics, and law and medicine, worked with victims of fertility fraud as they sought ways to develop legislation making the act a crime.

The Role Of Small Gtpases In Regulating Blood-Brain Barrier Mechanotransduction, Brandon Jude Deore

Theses and Dissertations

Fluid shear stress is an important mediator of vascular permeability, yet the molecular mechanisms underlying the effect of shear on the blood-brain barrier (BBB) have yet to be clarified in cerebral vasculature despite its importance for brain homeostasis.. Neurological symptoms including the formation of microclots, stroke, and other neurological pathologies associated with changes in cerebral blood flow are hallmarks of BBB dysfunction. The in vitro model used in this dissertation is compatible with real-time measurement of barrier function using a transendothelial electrical resistance as well as immunocytochemistry and dextran permeability assays. These experiments reveal that there is a threshold level …

Comparative Anatomical Study Of The Brachial Plexus Of Primates, Alison Leann Camero

Masters Theses

Old world monkeys, new world monkeys, and humans all originate from a common ancestor. Although humans and old world monkeys are phylogenetically more closely related, old world monkeys and new world monkeys have similar locomotion. A difference in muscle patterns exists between old world monkeys, new world monkeys, and humans. Different musculature may be due to differences in locomotive patterns and species-specific use of their forearms. Muscles in the forelimbs are innervated by the nerves of the brachial plexus. There are differences among the brachial plexuses of human and non-human primates as well as variability within the species.

In this …

An Application Of Tajfel’S Social Identity Theory To Understand Gamer As A Social Identity Among Saudi College-Level Students, Mohammad M. Assiri

Language, Literacy, and Sociocultural Studies ETDs

Understanding the social identity construction of Saudi college-level students who self-identify as gamers in Saudi Arabia is essential when designing a student-centered education. Although support exists within the literature for exploring what it means to be a gamer from the perspective of gamers, a review of the literature revealed a gap in this regard in the context of Saudi Arabia. Therefore, this grounded theory study explored self-identification as a gamer in Saudi Arabia using Tajfel's (1981) three tenets of self-identification with a group. A social identity framework was used to understand the characteristics of Saudi gamers, their positive or negative …

Ud In The News Aug. 13-19, University Of Dayton

News Releases

A pair of faculty wrote for The Conversation. The Journal of College Admission featured the UD Sinclair Academy. Regional and local media covered UD's move-in and record enrollment.

Mechanisms Of Carbapenemase-Mediated Resistance Among High-Risk Pseudomonas Aeruginosa Lineages In Peru, Isabella A. Tickler, Juan Carlos Gomez De La Torre, Luis Alvarado, Anne E. Obradovich, Fred C. Tenover

Biology Faculty Publications

Objectives: Pseudomonas aeruginosa is one of the leading causes of healthcare-associated infections globally. High-risk carbapenemase-encoding P. aeruginosa clones are disseminating in many regions. The aim of this study was to learn more about the lineages and mechanisms of resistance of P. aeruginosa circulating in Peru.

Methods: A total of 141 carbapenemase-producing isolates recovered from hospitalized and ambulatory patients in Lima were sequenced and analyzed to infer their lineages through whole-genome sequence typing (wgST) and to identify their antimicrobial resistance genes.

Results: wgST identified nine sequence types (STs); ST111 and ST357 were the most frequently encountered (44.0% and 38.3%, respectively), followed …

Maternal Early-Life Risk Factors And Later Gestational Diabetes Mellitus: A Cross-Sectional Analysis Of The Uae Healthy Future Study (Uaehfs), Nirmin F. Juber, Abdishakur Abdulle, Abdulla Aljunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S. Al Dhaheri, Eiman Alzaabi, Fatima Mezhal, Fatma Al-Maskari, Fatme Alanouti, Habiba Alsafar, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Michael Weitzman, Mohammad Al-Houqani, Mohammed Hag Ali, Naima Oumeziane, Omar El-Shahawy, Scott Sherman, Sharifa Alblooshi, Syed M. Shah, Tom Loney, Wael Almahmeed, Youssef Idaghdour, Raghib Ali

All Works

Limited studies have focused on maternal early-life risk factors and the later development of gestational diabetes mellitus (GDM). We aimed to estimate the GDM prevalence and examine the associations of maternal early-life risk factors, namely: maternal birthweight, parental smoking at birth, childhood urbanicity, ever-breastfed, parental education attainment, parental history of diabetes, childhood overall health, childhood body size, and childhood height, with later GDM. This was a retrospective cross-sectional study using the UAE Healthy Future Study (UAEHFS) baseline data (February 2016 to April 2022) on 702 ever-married women aged 18 to 67 years. We fitted a Poisson regression to estimate the …

Method Optimization For The Determination Of Cannabinoids In Blood By Liquid Chromatography Tandem Mass Spectrometry (Lc-Ms/Ms), Kevin D. Carrera

Student Theses

Delta-9-tetrahydrocannabinol (THC) continues to be one of the most popular drugs in the USA. Along with THC, other cannabinoids such as cannabidiol (CBD), are on the rise due to an increase in medicinal usage as well as the passage of different legislations removing these products from their current schedule I status. Thus, an urgency exists to develop robust and sensitive analytical methods to determine cannabinoids, especially THC, CBD and metabolites, in biological samples. The purpose of this study was to investigate different analytical procedures to determine the best method to identify and quantify CBD, THC and their metabolites in whole …

Consequences Of Biofilm Architecture On Vibrio Cholerae Ecology And Life History, Benjamin Ray Wucher

Dartmouth College Ph.D Dissertations

The diversity of microbes and the environments they inhabit are staggering. In many of these environments, bacteria have evolved to form sessile surface attached communities called biofilms. These biofilms have wide reaching impacts from importance in global carbon cycling, to persistent catheter infections, to biofouling and wastewater treatment. While many species of microbes form biofilms to survive in their environment, the architectures of these structures vary widely between organisms. Even though a great deal of work has been done to understand bacterial communities and their functions, little work has examined how the spatial aspects of biofilm architecture can affect the …

Editorial: Mitochondria, Metabolism And Cardiovascular Diseases, Jun-Ichiro Koga, Xinghui Sun, Masuko Ushio-Fukai

Department of Biochemistry: Faculty Publications

No abstract provided.

Human Total, Basal And Activity Energy Expenditures Are Independent Of Ambient Environmental Temperature, Xueying Zhang, Yosuke Yamada, Hiroyuki Sagayama, Philip N Ainslie, Ellen E Blaak, Maciej S Buchowski, Graeme L Close, Jamie A Cooper, Sai Krupa Das, Lara R Dugas, Michael Gurven, Asmaa El Hamdouchi, Sumei Hu, Noorjehan Joonas, Peter Katzmarzyk, William E Kraus, Robert F Kushner, William R Leonard, Corby K Martin, Erwin P Meijer, Marian L Neuhouser, Robert M Ojiambo, Yannis P Pitsiladis, Guy Plasqui, Ross L Prentice, Susan B Racette, Eric Ravussin, Leanne M Redman, Rebecca M Reynolds, Susan B Roberts, Luis B Sardinha, Analiza M Silva, Eric Stice, Samuel S Urlacher, Edgar A Van Mil, Brian M Wood, Alexia J Murphy-Alford, Cornelia Loechl, Amy H Luke, Jennifer Rood, Dale A Schoeller, Klaas R Westerterp, William W Wong, Herman Pontzer, John R Speakman, Iaea Dlw Database Consortium

Children’s Nutrition Research Center Staff Publications

Lower ambient temperature (Ta) requires greater energy expenditure to sustain body temperature. However, effects of Ta on human energetics may be buffered by environmental modification and behavioral compensation. We used the IAEA DLW database for adults in the USA (n = 3213) to determine the effect of Ta (−10 to +30°C) on TEE, basal (BEE) and activity energy expenditure (AEE) and physical activity level (PAL). There were no significant relationships (p > 0.05) between maximum, minimum and average Ta and TEE, BEE, AEE and PAL. After adjustment for fat-free mass, fat mass and age, statistically significant (p < 0.01) relationships between TEE, BEE and Ta emerged in females but the effect sizes were not biologically meaningful. Temperatures inside buildings are regulated at 18–25°C independent of latitude. Hence, adults in the US modify their environments to keep TEE constant across a wide range of external ambient temperatures.

Intermediates In Sars-Cov-2 Spike–Mediated Cell Entry, Tara C. Marcink, Thomas Kicmal, Emily Armbruster, Zhening Zhang, Gillian Zipursky, Kate L. Golub, Mohab Idris, Jonathan Khao, Jennifer Drew-Bear, Gael Mcgill, Tom Gallagher, Matteo Porotto, Amédée Des Georges, Anne Moscona

Advanced Science Research Center

SARS-CoV-2 cell entry is completed after viral spike (S) protein–mediated membrane fusion between viral and host cell membranes. Stable prefusion and postfusion S structures have been resolved by cryo–electron microscopy and cryo–electron tomography, but the refolding intermediates on the fusion pathway are transient and have not been examined. We used an antiviral lipopeptide entry inhibitor to arrest S protein refolding and thereby capture intermediates as S proteins interact with hACE2 and fusion-activating proteases on cell-derived target membranes. Cryo–electron tomography imaged both extended and partially folded intermediate states of S2, as well as a novel late-stage conformation on the pathway to …

Butte Priority Soils Operable Unit (Bpsou) Final Insufficiently Reclaimed Sites - Field Sampling Plan (Fsp) Bres No. 16 - Curry., Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Phase 2 Of Extracellular Rna Communication Consortium Charts Next-Generation Approaches For Extracellular Rna Research, Bogdan Mateescu, Jennifer C Jones, Roger P Alexander, Eric Alsop, Ji Yeong An, Mohammad Asghari, Alex Boomgarden, Laura Bouchareychas, Alfonso Cayota, Hsueh-Chia Chang, Al Charest, Daniel T Chiu, Robert J Coffey, Saumya Das, Peter De Hoff, Andrew Demello, Crislyn D'Souza-Schorey, David Elashoff, Kiarash R Eliato, Jeffrey L Franklin, David J Galas, Mark B Gerstein, Ionita H Ghiran, David B Go, Stephen Gould, Tristan R Grogan, James N Higginbotham, Florian Hladik, Tony Jun Huang, Xiaoye Huo, Elizabeth Hutchins, Dennis K Jeppesen, Tijana Jovanovic-Talisman, Betty Y S Kim, Sung Kim, Kyoung-Mee Kim, Yong Kim, Robert R Kitchen, Vaughan Knouse, Emily L Laplante, Carlito B Lebrilla, L James Lee, Kathleen M Lennon, Guoping Li, Feng Li, Tieyi Li, Tao Liu, Zirui Liu, Adam L Maddox, Kyle Mccarthy, Bessie Meechoovet, Nalin Maniya, Yingchao Meng, Aleksandar Milosavljevic, Byoung-Hoon Min, Amber Morey, Martin Ng, John Nolan, Getulio P De Oliveira Junior, Michael E Paulaitis, Tuan Anh Phu, Robert L Raffai, Eduardo Reátegui, Matthew E Roth, David A Routenberg, Joel Rozowsky, Joseph Rufo, Satyajyoti Senapati, Sigal Shachar, Himani Sharma, Anil K Sood, Stavros Stavrakis, Alessandra Stürchler, Muneesh Tewari, Juan P Tosar, Alexander K Tucker-Schwartz, Andrey Turchinovich, Nedyalka Valkov, Kendall Van Keuren-Jensen, Kasey C Vickers, Lucia Vojtech, Wyatt N Vreeland, Ceming Wang, Kai Wang, Zeyu Wang, Joshua A Welsh, Kenneth W Witwer, David T W Wong, Jianping Xia, Ya-Hong Xie, Kaichun Yang, Mikołaj P Zaborowski, Chenguang Zhang, Qin Zhang, Angela M Zivkovic, Louise C Laurent

Faculty, Staff and Student Publications

The extracellular RNA communication consortium (ERCC) is an NIH-funded program aiming to promote the development of new technologies, resources, and knowledge about exRNAs and their carriers. After Phase 1 (2013-2018), Phase 2 of the program (ERCC2, 2019-2023) aims to fill critical gaps in knowledge and technology to enable rigorous and reproducible methods for separation and characterization of both bulk populations of exRNA carriers and single EVs. ERCC2 investigators are also developing new bioinformatic pipelines to promote data integration through the exRNA atlas database. ERCC2 has established several Working Groups (Resource Sharing, Reagent Development, Data Analysis and Coordination, Technology Development, nomenclature, …

Investigation Of The Hydrogen Sulfide Signaling Pathway In Schwann Cells During Peripheral Nerve Degeneration: Multi-Omics Approaches, Yoo Lim Chun, Won-Joon Eom, Jun Hyung Lee, Thy N C Nguyen, Ki-Hoon Park, Hyung-Joo Chung, Han Seo, Youngbuhm Huh, Sang Hoon Kim, Seung Geun Yeo, Wonseok Park, Geul Bang, Jin Young Kim, Min-Sik Kim, Na Young Jeong, Junyang Jung

Faculty, Staff and Student Publications

No abstract provided.

Analysis Of Cancer Patients' Understanding Of Clinical Trials To Help Identifying Enrolment Barriers In Clinical Trials For Stanford Cancer Centers, Debjani Ghoshal

Master's Projects and Capstones

Clinical trials are studies conducted as a part of research to evaluate the safety and efficacy of a drug and device as a treatment option. Enrolment in a clinical trial is very critical for the success of the interventions. Therefore, it is important to improve the patient recruitment to clinical trials, specifically in oncology. There are many barriers which prevents from a successful enrolment of cancer patients in a clinical trial. And due to these barriers, there are low participations in clinical trials. There are many factors that influence the decision of the patients to participate in a clinical …

Omicron Spike Function And Neutralizing Activity Elicited By A Comprehensive Panel Of Vaccines, John E. Bowen, Amin Addetia, Ha V Dang, Cameron Stewart, Jack T. Brown, William K. Sharkey, Kaitlin R. Sprouse, Kumail Ahmed, Asefa Shariq Ansari, Najeeha Talat Iqbal

Department of Paediatrics and Child Health

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern comprises several sublineages, with BA.2 and BA.2.12.1 having replaced the previously dominant BA.1 and with BA.4 and BA.5 increasing in prevalence worldwide. We show that the large number of Omicron sublineage spike mutations leads to enhanced angiotensin-converting enzyme 2 (ACE2) binding, reduced fusogenicity, and severe dampening of plasma neutralizing activity elicited by infection or seven clinical vaccines relative to the ancestral virus. Administration of a homologous or heterologous booster based on the Wuhan-Hu-1 spike sequence markedly increased neutralizing antibody titers and breadth against BA.1, BA.2, BA.2.12.1, BA.4, and …

A Study Of Red Snapper (Lutjanus Campechanus) Ecology In The Northern Gulf Of Mexico And The Effect Of Variable River Outflow Using Stable Isotope Analysis Of The Food Web And Eye Lenses, Caitlin C. Slife

Dissertations

In the Mississippi Bight and surrounding waters, river outflow impacts the basal resources of the Red Snapper food web, altering carbon sources and impacting prey and predator isotopes. In this study, the impact of riverine outflow on nutrients, particulate organic matter (POM), and physical water parameters on Red Snapper and their food web was analyzed using stable isotope and stomach content analysis over 5 years. The Mississippi, Pearl, Pascagoula, and Mobile rivers were included in the analysis of river impact. The Mississippi and Mobile rivers were found to significantly impact nutrients and POM in the region. River outflow was also …

A User-Friendly Tool For Cloud-Based Whole Slide Image Segmentation With Examples From Renal Histopathology, Brendon Lutnick, Sanjay Jain, Et Al

2020-Current year OA Pubs

Background: Image-based machine learning tools hold great promise for clinical applications in pathology research. However, the ideal end-users of these computational tools (e.g., pathologists and biological scientists) often lack the programming experience required for the setup and use of these tools which often rely on the use of command line interfaces.

Methods: We have developed

Results: By segmenting glomeruli, interstitial fibrosis and tubular atrophy, and vascular structures from renal and non-renal WSIs, we demonstrate the scalability, best practices for transfer learning, and effects of dataset variability. Finally, we demonstrate an application for animal model research, analyzing glomerular features in three …

The Missing Link Between Standing-And Traveling-Wave Resonators, Qi Zhong, Haoqi Zhao, Liang Feng, Kurt Busch, Sahin K. Özdemir, Ramy El-Ganainy

Michigan Tech Publications, Part 1

Optical resonators are structures that utilize wave interference and feedback to confine light in all three dimensions. Depending on the feedback mechanism, resonators can support either standing-or traveling-wave modes. Over the years, the distinction between these two different types of modes has become so prevalent that nowadays it is one of the main characteristics for classifying optical resonators. Here, we show that an intermediate link between these two rather different groups exists. In particular, we introduce a new class of photonic resonators that supports a hybrid optical mode, i.e. at one location along the resonator the electromagnetic fields associated with …

2022-08-19 Institutional Animal Care And Use Committee Meeting Minutes, Morehead State University. Faculty Senate., Institutional Animal Care And Use Committee.

Faculty Senate Records

Institutional Animal Care and Use Committee meeting minutes from August 19, 2022.

Regulation Of Drosophila Oviduct Muscle Contractility By Octopamine, Sonali A Deshpande, Ethan W Rohrbach, James D Asuncion, Jenna Harrigan, Aditya Eamani, Ellery H Schlingmann, Daniel J Suto, Pei-Tseng Lee, Felix E Schweizer, Hugo J Bellen, David E Krantz

Duncan NRI Faculty and Staff Publications

Octopamine is essential for egg-laying in

Diving Into The Vertical Dimension Of Elasmobranch Movement Ecology, Samantha Andrzejaczek, Tim C D Lucas, Maurice C Goodman, Nigel E Hussey, Amelia J Armstrong, Aaron Carlisle, Daniel M Coffey, Adrian C Gleiss, Charlie Huveneers, David M P Jacoby, Mark G Meekan, Johann Mourier, Lauren R Peel, Kátya Abrantes, André S Afonso, Matthew J Ajemian, Brooke N Anderson, Scot D Anderson, Gonzalo Araujo, Asia O Armstrong, Pascal Bach, Adam Barnett, Mike B Bennett, Natalia A Bezerra, Ramon Bonfil, Andre M Boustany, Heather D Bowlby, Ilka Branco, Camrin D Braun, Edward J Brooks, Judith Brown, Patrick J Burke, Paul Butcher, Michael Castleton, Taylor K Chapple, Olivier Chateau, Maurice Clarke, Rui Coelho, Enric Cortes, Lydie I E Couturier, Paul D Cowley, Donald A Croll, Juan M Cuevas, Tobey H Curtis, Laurent Dagorn, Jonathan J Dale, Ryan Daly, Heidi Dewar, Philip D Doherty, Andrés Domingo, Alistair D M Dove, Michael Drew, Christine L Dudgeon, Clinton A J Duffy, Riley G Elliott, Jim R Ellis, Mark V Erdmann, Thomas J Farrugia, Luciana C Ferreira, Francesco Ferretti, John D Filmalter, Brittany Finucci, Chris Fischer, Richard Fitzpatrick, Fabien Forget, Kerstin Forsberg, Malcolm P Francis, Bryan R Franks, Austin J Gallagher, Felipe Galvan-Magana, Mirta L García, Troy F Gaston, Bronwyn M Gillanders, Matthew J Gollock, Jonathan R Green, Sofia Green, Christopher A Griffiths, Neil Hammerschlag, Abdi Hasan, Lucy A Hawkes, Fabio Hazin, Matthew Heard, Alex Hearn, Kevin J Hedges, Suzanne M Henderson, John Holdsworth, Kim N Holland, Lucy A Howey, Robert E Hueter, Nicholas E Humphries, Melanie Hutchinson, Fabrice R A Jaine, Salvador J Jorgensen, Paul E Kanive, Jessica Labaja, Fernanda O Lana, Hugo Lassauce, Rebecca S Lipscombe, Fiona Llewellyn, Bruno C L Macena, Ronald Mambrasar, Jaime D Mcallister, Sophy R Mccully Phillips, Frazer Mcgregor, Matthew N Mcmillan, Lianne M Mcnaughton, Sibele A Mendonça, Carl G Meyer, Megan Meyers, John A Mohan, John C Montgomery, Gonzalo Mucientes, Michael K Musyl, Nicole Nasby-Lucas, Lisa J Natanson, John B O'Sullivan, Paulo Oliveira, Yannis P Papastamtiou, Toby A Patterson, Simon J Pierce, Nuno Queiroz, Craig A Radford, Andy J Richardson, Anthony J Richardson, David Righton, Christoph A Rohner, Mark A Royer, Ryan A Saunders, Matthias Schaber, Robert J Schallert, Michael C Scholl, Andrew C Seitz, Jayson M Semmens, Edy Setyawan, Brendan D Shea, Rafid A Shidqi, George L Shillinger, Oliver N Shipley, Mahmood S Shivji, Abraham B Sianipar, Joana F Silva, David W Sims, Gregory B Skomal, Lara L Sousa, Emily J Southall, Julia L Y Spaet, Kilian M Stehfest, Guy Stevens, Joshua D Stewart, James A Sulikowski, Ismail Syakurachman, Simon R Thorrold, Michele Thums, David Tickler, Mariana T Tolloti, Kathy A Townsend, Paulo Travassos, John P Tyminski, Jeremy J Vaudo, Drausio Veras, Laurent Wantiez, Sam B Weber, R J David Wells, Kevin C Weng, Bradley M Wetherbee, Jane E Williamson, Matthew J Witt, Serena Wright, Kelly Zilliacus, Barbara A Block, David J Curnick

Staff and Researcher Publications

Knowledge of the three-dimensional movement patterns of elasmobranchs is vital to understand their ecological roles and exposure to anthropogenic pressures. To date, comparative studies among species at global scales have mostly focused on horizontal movements. Our study addresses the knowledge gap of vertical movements by compiling the first global synthesis of vertical habitat use by elasmobranchs from data obtained by deployment of 989 biotelemetry tags on 38 elasmobranch species. Elasmobranchs displayed high intra- and interspecific variability in vertical movement patterns. Substantial vertical overlap was observed for many epipelagic elasmobranchs, indicating an increased likelihood to display spatial overlap, biologically interact, and …

The Feel Of Inclusivity, Kristen M Patti, Gary J Patti

2020-Current year OA Pubs

Collaboration between diverse groups with different perspectives promotes scientific discovery. To enhance these partnerships and facilitate communication, innovative advances in universal design are essential.

Cochlear Ribbon Synapse Maturation Requires Nlgn1 And Nlgn3, Miguel A Ramirez, Yuzuru Ninoyu, Cayla Miller, Leonardo R Andrade, Seby Edassery, Ewa Bomba-Warczak, Briana Ortega, Uri Manor, Mark A Rutherford, Rick A Friedman, Jeffrey N Savas

2020-Current year OA Pubs

Hearing depends on precise synaptic transmission between cochlear inner hair cells and spiral ganglion neurons through afferent ribbon synapses. Neuroligins (Nlgns) facilitate synapse maturation in the brain, but they have gone unstudied in the cochlea. We report