Digital Commons Network^™

Monkeypox: Experts Give Virus Variants New Names

Saudi Medical Journal

No abstract provided.

Book Review Of: The Concealed Influence Of Custom: Hume's Treatise From The Inside Out, Angela M. Coventry

Philosophy Faculty Publications and Presentations

Review of the book, Jay L. Garfield, The Concealed Influence of Custom: Hume's Treatise from the Inside Out, Oxford University Press, 2019.

Light4health Elearning Course: Health Research For Interior Lighting Design. Re-Thinking Design Approaches Based On Science, K. M. Zielinska-Dabkowska, Lyn Godley, F. Kyriakidou, U. C. Besenecker, G. Triantafyllidis

Kanbar College Faculty Papers

This paper presents the results of 'Light4Health' (L4H), a three-year EU Erasmus+ Strategic Partnership grant project (2019-2021), which investigated, systematized and taught health-related research on the impact of natural and artificial light on human health and well-being relevant to indoor lighting design. The objective was to re-think evidence-based lighting design approaches for residential, working/educational, and healthcare spaces, in order to develop a novel cross-disciplinary eLearning platform, that intersects lighting design and current peer-reviewed health research through a select combination of the most relevant research, methods, and tools. The content was developed through teaching workshops with international researchers, teachers, and students. …

Biob 340.01: Biology And Management Of Fishes, Lisa A. Eby

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Pubh 591.54: Indoor Environmental Quality Management, Tony John Ward

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Chmy 123.Bh00: Introduction To General, Organic And Biochemistry - Hamilton, Jennifer E. Johnson

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Is Strongyloides Stercoralis Hyperinfection Induced By Gglucocorticoids A Result Of Both Suppressed Host Immunity And Altered Parasite Genetics?, De'broski R Herbert, Jonathan D C Stoltzfus, Heather L Rossi, David Abraham

Department of Microbiology and Immunology Faculty Papers

The gastrointestinal (GI) nematode Strongyloides stercoralis (S.s.) causes human strongyloidiasis, a potentially life-threatening disease that currently affects over 600 million people globally. The uniquely pernicious aspect of S.s. infection, as compared to all other GI nematodes, is its autoinfective larval stage (L3a) that maintains a low-grade chronic infection, allowing undetectable persistence for decades. Infected individuals who are administered glucocorticoid therapy can develop a rapid and often lethal hyperinfection syndrome within days. Hyperinfection patients often present with dramatic increases in first- and second-stage larvae and L3a in their GI tract, with L3a widely disseminating throughout host organs leading to sepsis. How …

Role Of The G Protein Beta Gamma Subunits In Serotonin Transporter Dynamics, Nora Awadallah

Dissertations, Theses, and Capstone Projects

Serotonin is a vital neurotransmitter and hormone with significant roles in almost every organ system. In the central nervous system, serotonin mediates physiological functions that in turn guide behavior and mood. Here, serotonin is released from serotonergic neurons and exerts its effects through serotonin receptors. Regulation of serotonin neurotransmission is important for the maintenance of its physiological functions; thus, extracellular serotonin must be sequestered to limit the intensity and duration of serotonin transmission. Disproportionate transmission is strongly linked with neurological and psychiatric ailments.

Extracellular serotonin levels are primarily mediated by the serotonin transporter (SERT), a critically important plasma membrane protein …

Development And Characterization Of A Novel, Genetically- Encoded Sensor To Image Sonic Hedgehog Signaling In Functional Circuits, Sonia Bernal

Dissertations, Theses, and Capstone Projects

Dynamic neurotransmitter and neuromodulator signaling in functional circuits is the neural substrate of animal behavior and cognition. The study of said circuits requires tools with sufficient spatiotemporal dynamics that can probe complex signaling patterns and decode their functional relevance by coupling the signal to behavioral output, ideally in awake, behaving animals. Much is known about the role of classical neurotransmitters such as dopamine in behavior, but a wide variety of peptides and small molecules also regulate neuronal transmission. One of these is Shh, whose presence has been observed in a variety of brain regions known to modulate movement, perception, and …

Sensitized Photooxidation Of Prenylated Compounds: Mechanisms Of Downstream Dark Effects And Phototoxicity Priming, Shakeela Jabeen

Dissertations, Theses, and Capstone Projects

This thesis consists of four chapters as detailed below.

Chapter 1 discusses a singlet oxygen priming mechanism. Airborne singlet oxygen derived from photosensitization of triplet dioxygen is shown to react with an alkene surfactant (8-methylnon-7-ene-1 sulfonate) leading to ‘ene’ hydroperoxides that in the dark inactivate planktonic E. coli. The ‘ene’ hydroperoxide photoproducts are not toxic on their own, but they become toxic after the bacteria are pretreated with singlet oxygen. The total quenching rate constant (k_T) of singlet oxygen of the alkene surfactant was measured to be 1.1 × 10⁶ M⁻¹ s^{− …}

Holding States Accountable For Harmful Algal Blooms: Florida's Water Crisis In Focus, Jason Totoiu, Jaclyn Lopez

University of Florida Journal of Law & Public Policy

Scientists generally agree that agricultural runoff is a principal source of nutrient pollution in the United States. Intensive agricultural practices have resulted in decades of phosphorus and nitrogen accumulating in the natural system which continue to contribute substantially to nutrients entering watersheds. Coupled with failed water quality control measures, this water pollution has led to some of the worst harmful algal blooms (HABs) in recorded history. These nonpoint sources need to be addressed to restore and protect water quality.

Florida’s Lake Okeechobee watershed provides an apt case study. Commonly referred to as the “liquid heart” of the Everglades, the lake …

Substrate Stiffness Modulates Migration And Local Intercellular Membrane Motion In Pulmonary Endothelial Cell Monolayers, Sunita Subedi Paudel, Althea Deweever, Sarah Sayner, Troy Stevens, Dhananjay T. Tambe

University Faculty and Staff Publications

The pulmonary artery endothelium forms a semipermeable barrier that limits macromolecular flux through intercellular junctions. This barrier is maintained by an intrinsic forward protrusion of the interacting membranes between adjacent cells. However, the dynamic interactions of these membranes have been incompletely quantified. Here, we present a novel technique to quantify the motion of the peripheral membrane of the cells, called paracellular morphological fluctuations (PMFs), and to assess the impact of substrate stiffness on PMFs. Substrate stiffness impacted large-length scale morphological changes such as cell size and motion. Cell size was larger on stiffer substrates, whereas the speed of cell movement …

Cell-Intrinsic Melanin Fails To Protect Melanocytes From Ultraviolet-Mutagenesis In The Absence Of Epidermal Melanin, Tirzah J. Weiss, Emma R. Crawford, Valentina Posada, Hafeez Rahman, Tong Liu, Brandon M. Murphy, Tiffany E. Arnold, Shannon Gray, Zhexuan Hu, Rebecca C. Hennessey, Lianbo Yu, John August D'Orazio, Craig J. Burd, Jonathan H. Zippin, Douglas Grossman, Christin E. Burd

Markey Cancer Center Faculty Publications

Melanin is a free-radical scavenger, antioxidant, and broadband absorber of ultraviolet (UV) radiation which protects the skin from environmental carcinogenesis. However, melanin synthesis and UV-induced reactive melanin species are also implicated in melanocyte genotoxicity. Here, we attempted to reconcile these disparate functions of melanin using a UVB- sensitive, NRAS-mutant mouse model, TpN. We crossed TpN mice heterozygous for an inactivating mutation in Tyrosinase to produce albino and black littermates on a C57BL/6J background. These animals were then exposed to a single UVB dose on postnatal day three when keratinocytes in the skin have yet to be melanized. Approximately one-third (35%) …

Low-Cost Compact Optical Spectroscopy And Novel Spectroscopic Algorithm For Point-Of-Care Real-Time Monitoring Of Nanoparticle Delivery In Biological Tissue Models, Zahid Hasan, Jing Yan, Zhongchao Yi, Madison O. Korfhage, Sheng Tong, Caigang Zhu

Markey Cancer Center Faculty Publications

Objective: Real-time monitoring of nanoparticle delivery in biological models is essential to optimize nanoparticle- mediated therapies. However, few techniques are available for convenient real-time monitoring of nanoparticle concentrations in tissue samples. This work reported novel optical spectroscopic approaches for low-cost point-of-care real-time quantification of nanoparticle concentrations in biological tissue samples.

Methods: Fiber probe measured diffuse reflectance can be described with a simple analytical model by introducing an explicit dependence on the reduced scattering coefficient. Relying on this, the changes on the inverse of diffuse reflectance are proportional to absorption change when the scattering perturbation is negligible. We developed this model …

Minutes From September 1 2022, University Senate

University Senate Minutes

Minutes from September 1 2022 University Senate Meeting

Polyploidy Events Shaped The Expansion Of Transcription Factors In Cucurbitaceae And Exploitation Of Genes For Tendril Development, Yu Zhang, Yingchao Zhang, Bing Li, Xiao Tan, Changping Zhu, Tong Wu, Shuyan Feng, Qihang Yang, Shaoqin Shen, Tong Yu, Zhuo Liu, Xiaoming Song

Department of Food Science and Technology: Faculty Publications

Cucurbitaceae is one of the most important plant families distributed worldwide. Transcription factors (TFs) regulate plant growth at the transcription level. Here, we performed a systematic analysis of 42 641 TFs from 63 families in 14 Cucurbitaceae and 10 non-cucurbit species. Whole-genome duplication (WGD) was the dominant event type in almost all Cucurbitaceae plants. The TF families were divided into 1 210 orthogroups (OGs), of which, 112 were unique to Cucurbitaceae. Although the loss of several gene families was detected in Cucurbitaceae, the gene families expanded in five species that experienced a WGD event comparing with grape. Our findings revealed …

Prevalence Of Carbapenemase Genes Among Multidrug-Resistant Pseudomonas Aeruginosa Isolates From Tertiary Care Centers In Southern Thailand, Phanvasri Saengsuwan, Narongdet Kositpantawong, Soontara Kawila, Wichien Patugkaro, Chonticha Romyasamit

Saudi Medical Journal

Objectives: To assess the prevalence of carbapenemase genes among multidrug-resistant Pseudomonas aeruginosa ( P. aeruginosa ) isolates from tertiary care centers in Southern Thailand. Methods: The prevalence of carbapenemase genes in P. aeruginosa isolates collected from patients hospitalized between 2015-2017 in 2 tertiary care hospitals in Songkhla Province, Southern Thailand, was investigated. Standard laboratory procedures were followed and disk diffusion test was used for bacterial identification and susceptibility evaluations. Carbapenemase genes were detected using multiplex polymerase chain reaction (PCR) and genotyping by pulsed field gel electrophoresis. Results: Among the 289 P. aeruginosa isolates, 55% was from sputum, 19.4% was from …

Double Malignancy And A Mycobacterial Infection In A Rheumatoid Arthritis Patient, Huda Alfaris, Sarah A. Alkathiri, Doha Babelli, Fahdah Alokaily

Saudi Medical Journal

Rheumatoid arthritis is a common autoimmune disease. Malignancy is a serious complication of rheumatoid arthritis and its treatment. In this article, we discuss a 61-year-old woman who is a known case of Rheumatoid arthritis and secondary Sjögren’s syndrome treated with disease-modifying anti-rheumatoid drugs and multiple lines of biological therapies. She was found to have recto-sigmoid cancer, disseminated tuberculosis infection, and acute lymphoid leukemia at different intervals of treatment. Therefore, it is advisable to initiate appropriate screening programs that target high-risk people for malignancy.

A Study On The Impact Of Technological Innovation Attributes On Listing Success Rate And Post-Listing Performance, Yijun Xu

Dissertations and Theses Collection (Open Access)

"Key and core technology" enterprises form the backbone of great powers. China’s STAR Market (technological innovation board) is committed to implementing strategies that will lead to technological innovation-driven sustainable development and strengthen the country by building a secure and independent industrial chain that can support the development of cutting-edge technology. From the outset, the STAR Market put forward clear requirements for "key and core technology" enterprises. The technological innovation attributes of the enterprises listed on the STAR Market are the most essential core characteristics, but a question arises as to how best to evaluate their technological innovation attributes. Are these …

Arthroscopic Suprapectoral Biceps Tenodesis: The Best Of Both Worlds, Tyler Pratte, Tyler Smith, Alfonso Arevalo, Joseph Wazen, David Rubenstein

Orthopedic Surgery Resident Research

Biceps tendinopathy and superior labrum anterior posterior lesions are a common source of shoulder pain and disability and can be effectively treated with biceps tenodesis. There are a variety of open and arthroscopic tenodesis techniques, but no one technique has demonstrated superiority. Arthroscopic techniques often disregard the extra-articular portions of the biceps tendon as a potential source of pain. Open techniques address this concern; however, they can be associated with wound complications, increased blood loss, nerve injury, and disruptions to surgical workflow. Here, we describe an all arthroscopic tenodesis technique at the suprapectoral zone of the tendon. This method addresses …

Evidence Of Likely Autochthonous Chagas Disease In The Southwestern United States: A Case Series Of Trypanosoma Cruzi Seropositive Blood Donors, Mary K. Lynn, Kyndall C. Dye-Braumuller, Norman L. Beatty, Patricia L. Dorn, Stephen A. Klotz, Susan L. Stramer, Rebecca L. Townsend, Hany Kamel, Jacquelyn M. Vannoy, Patrick Sadler, Susan P. Montgomery, Hilda N. Rivera, Melissa Nolan Ph.D., Mph

Faculty Publications

Background Chagas disease is a parasitic infection that can insidiously cause non-ischemic cardiomyopathy. Given the largely silent nature of this progressive disease, asymptomatic blood donors pose potential blood transfusion risk. Blood donation screening has become an unintentional form of Chagas disease surveillance, with thousands of new cases identified since national surveillance was initiated in 2007.

Study Design and Methods We recruited T. cruzi-positive blood donors identified from California and Arizona blood centers for confirmatory blood screening and assessment of lifetime infection risk.

Results Among eight suspected cases, we identified four confirmed US autochthonous infections. The current manuscript details the …

Characterization Of Superconductor Materials Doped With Nanoparticles On Their Properties: Review Article, Hanan Kadhim, Noor Hasan, Adawiya Haider

Journal of Applied Sciences and Nanotechnology

Revolutionary developments have been started in the field of superconductors since their discovery. High-temperature superconductors have been a focus of attention in advanced technology for many scientists because of their potential applications. Therefore, many changes are made in the products that use such materials. It remains one of the most exciting research fields and can revolutionize the physics and technology of the future. It is required to understand and learn the history and basic principles of Superconductivity for its better implications. Considering its recent discoveries, its current applications can be studied. The mechanism of ‘HTS’ is much easier to understand …

Spectroscopic And Structural Analysis Of Aluminum Bulk And Nanoparticles: A Comparative Study, Hajir M. Fadhil, Khaleel I. Hassoon, Hyder A. Salih

Journal of Applied Sciences and Nanotechnology

In the present work, Laser Induced Breakdown Spectroscopy (LIBS) has been utilized to investigate two forms of aluminum samples, namely Al in the form of the nanoparticles (NPs) and a bulk (pellet). The Al target was irradiated by pulsed Nd-YAG laser with wavelength 1064 nm to produce plasma. The plasm spectrum is analyzed in the wavelength range between 250 nm and 700 nm. Some plasma parameters were calculated, including electron temperature (����), plasma density (ne) and Debye length (����) for different laser energies. The temperature of electrons was computed employing the Boltzmann plot technique, and the electrons density was computed …

Antibacterial Studying Of Silver Nanoparticles Synthesized By Chemical Reduction Method Using Different Stabilized Concentrations, Zahraa Ghazi, Mohammad Mohammad, Manal Abbood, Amal Hussein

Journal of Applied Sciences and Nanotechnology

Silver nanoparticles were prepared by the chemical reduction method. Silver nitrate was taken as a metal precursor and sodium borohydride as a reducing agent with polyvinyl alcohol (PVA) stabilizers of different concentrations, polyvinylpyrrolidone (PVP). X-ray diffraction (XRD), transmission electron microscopy (TEM), and atomic force microscopy (AFM) techniques have been used, these measurement results showed that the prepared material is silver nanoparticles. The average size of silver nanoparticles using the Scherrer equation with values ranging from 8.49-12.15nm. TEM images showed that the silver nanoparticles are spherical in size between 5-47nm. Nanoscale distribution of silver nanoparticles (AgNPs) prepared at different concentrations was …

Preparation Of Cellulose Acetate Nanocomposite Films Based On Tio2-Zno Nanoparticles Modification As Food Packaging Applications, Hajer Ali, Nahida Hameed

Journal of Applied Sciences and Nanotechnology

To develop bio-packaging materials, nanocomposite films of cellulose acetate reinforced with titanium dioxide and zinc oxide nanoparticles were prepared, by the casting method at different weight ratios of ZnO nanoparticles (1.5, 2, and 2.5) wt% and a constant weight ratio of 2 wt% TiO2. ZnO and TiO2 nanoparticles were tested using scanning electron microscopy (SEM). The mechanical properties (tensile strength and elongation) were improved at a fixed level of Cellulose Acetate+ 2% TiO2+1.5wt% ZnO loading. Beyond that level of loading, they decreased. The tensile strength was decreased due to some degrees of agglomeration of filler particles above a critical content. …

Chitosan/Pva/Peg Blend Strengthened With Mgo Nanoparticles For Antibacterial Application, Ishraq Fadhil, Balqees Aldabbagh, Wijdan Mahdi

Journal of Applied Sciences and Nanotechnology

Chitosan holds net ionic positive charges, which contribute its ability to chemically bind with negatively charged fats, lipids, metal ions, proteins, and microorganisms. Magnesium oxide (MgO) nanoparticles are important inorganic materials with a wide band-gap used in many applications such as catalysts, antibacterial and medical products. The aim of this study was to investigate the effect of Chitosan (CHT) hydrogel loaded MgO nanoparticles on the bacterial growth. CHT/ poly vinyl alcohol (PVA)/ poly ethylene glycol (PEG) hydrogel was blended with various amounts of MgO nanoparticles. The surface morphology of the obtained blends was investigated by Field Emission Scanning Electron Microscope …

Study Of Some Properties Of Pbi2 Deposited On Porous Silicon Using Thermal Evaporation Technique For Many Applications, Suha Ali, Mohammed Mohammed, Fatima Sultan

Journal of Applied Sciences and Nanotechnology

The present work is a study of some properties of PbI2 deposited on porous silicon (n-PSi) by using the thermal evaporation technique. X-ray diffraction, scanning electron microscopy, UV–Vis spectrophotometer, and FTIR analysis were used to characterize the structural, optical, and morphological properties of n-Psi. X-ray diffraction showed that the PbI2 film has a hexagonal polycrystalline structure, while FE-SEM images showed porous silicone in Photoelectrochemical etching, the pore distribution is irregular and the pore refers to the increased surface area of the silicon. SEM images of pbI2 film showed that particles were scattered and resembled gravel in size. The estimated optical …

Preparation, Characterization And Mimetic Activities Of Fe2o3 And Fe3o4 Nanoparticles As Catalase And Peroxidase, Alaa Majeed, Rashed Rasheed

Journal of Applied Sciences and Nanotechnology

Different iron oxide nanoparticles (Fe3O4 and Fe2O3) were prepared by the sol-gel method (titration). The prepared nanoparticles were heated at 90 and 400°C. The morphology surface and structures were characterized by Fourier Transform Infra-Red (FT-IR) and Ultraviolet/Visible (Uv/Visible) measurements, X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), and Atomic Force Microscope (AFM). The enzyme mimetic activities of these nanoparticles (Fe3O4 and Fe2O3) such as two enzymes (Catalase (CAT), and Peroxidase (Pxase)) were measured. The results showed the iron oxides (Fe2O3) heated at 90°C, have the maximum activity (189.99 K.min-1) as catalase (CAT). While the iron oxides (Fe3O4) heated at 90°C, have …

Csd 110.50: Introduction To Speech, Language, And Audiology, Haley Permar

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Pubh 101s.01: Introduction To Public Health, Curtis W. Noonan

University of Montana Course Syllabi, 2021-2025

No abstract provided.