Digital Commons Network^™

Choosing Death: The Moral Legitimacy Of Voluntary Active Euthanasia, Emma Rougeou

Honors Theses

During the last three decades, the issue of physician assisted suicide has captivated the interest of private citizens and state legislatures. Thinking about the matter of end-of-life concerns, particularly surrounding euthanasian (practices that hasten the deaths of suffering terminally ill people) have shifted. Views of private citizens and state-level legislation reflects a “slow shift to more permissive attitudes” (Cohen et al., 2012). Meanwhile, as recently as March 2026, state legislators in conjunction with the NY State Governor, passed a bill legalizing medical aid in dying for terminally ill patients. This thesis is intended to thoughtfully contribute to meaningful discourse on …

Urea-Based Boronium Salts As Antimicrobial Agents, Gabriel Allen Merchant

Honors Theses

Quaternary ammonium compounds (QACs) are widely used in disinfectants due to their ability to inhibit the growth of and eliminate microbes. The potency, broad-spectrum activity, and low cost of QACs have made them a cornerstone of modem hygiene. In recent years, QACs have garnered many health and safety concerns due to their overuse and subsequent accumulation in the environment. The increased use of QACs has further led to an increase in antimicrobial-resistant bacteria, making the synthesis of novel antibacterial compounds vital to combat this growing threat. Recent advances in boronium salts offer a unique alternative to address these adverse effects. …

Spectral Characterization Of Colorectal Cancer Using Excitation-Scanning Hyperspectral Imaging, Natalie Hadad

Honors Theses

Colorectal cancer is one of the most common and deadly cancers worldwide, with a lifetime risk of approximately one in twenty-three for men and one in twenty-five for women. Although early detection significantly improves survival, current diagnostic approaches such as tissue biopsy are invasive, reliant on subjective interpretation, have extended turnaround times, and risk missing flat or depressed lesions that are more difficult to detect than raised polyps. These limitations highlight the need for objective, minimally invasive technologies capable of detecting early tissue changes. This study investigates excitation-scanning hyperspectral imaging (Ex-HSI) as a label-free optical approach for identifying colorectal cancer–associated …

Novel Biomarker Discovery In Multiple Sclerosis, Manisha Gangasani

Honors Theses

Multiple Sclerosis (MS) is a chronic neuroinflammatory disorder affecting the brain, spinal cord, and optic nerve. Patients experience cognitive, motor, autonomic, and emotional symptoms that often overlap with other neurological conditions, making early diagnosis challenging. Current diagnostic criteria require evidence of lesions with dissemination in time and space. Racial disparities in MS outcomes are well documented, with Black individuals often exhibiting greater disease severity, higher relapse rates, and increased disability compared to White individuals. These differences likely reflect a combination of genetic, biological, environmental, and healthcare access factors, underscoring the need to improve early diagnosis and reduce inequities in care. …

Characterization Of Circulating Extracellular Proteome In Plasma Samples Of Triple-Negative Breast Cancer Patients, Brionna Wilson

Honors Theses

Extracellular vesicles (EVs) are membrane-bound vesicles secreted by cells in the body that play an important role in intercellular signaling, immune modulation, and transfer of biomolecules between cells. EV s reflect the physiological state of their cells of origin, so they are being explored as potential noninvasive biomarkers for cancer detection and monitoring. Triple-negative breast cancer (TNBC), an aggressive subtype lacking targeted therapies, is difficult to detect early and currently has no reliable prognostic biomarkers. This study aimed to quantify EV concentrations in the blood serum of TNBC patients (n=40) compared with cancer-free healthy controls (n=35) as well as determine …

Developing A Protocol For Non-Cellular Transplantation Of Donor Mitochondria Into Recipient Cells, Andrew Parton

Honors Theses

Tumor innervation has emerged as a critical feature of cancer progression, with increased nerve density correlating with enhanced aggressiveness, metastatic dissemination, and poor clinical outcome. However, the functional contribution of neurons to tumor biology remains incompletely defined. We recently identified the intercellular transfer of mitochondria from neurons to cancer cells as a mechanism that promotes tumor progression. We therefore hypothesized that disruption of this transfer could attenuate tumor aggressivity. To directly investigate this process, we developed an approach to isolate mitochondria from donor cells and transplant them into recipient cancer cells independently of canonical cell-cell interactions. Transferred mitochondria were tracked …

Volunteer Spotlighting: Costly Signaling To Promote Volunteerism, Clyde A. Raible V

Master's Theses

Prosocial behaviors, because they are initially costly and do not guarantee a direct benefit to the actor, can nonetheless increase social status by signaling a willingness to incur cost on behalf of another. Given this signal value, nonprofit organizations may be able to leverage this knowledge to increase donations, such as through the provisioning of attention to, and recognition of, volunteers through social media. I predicted that the costliness of spotlighted behavior and the target signal clarity (i.e., individual vs. group spotlight) would interact with participants’ dispositional dominance and prestige-based status motives to influence volunteerism interest. To explore these associations, …

Assessment Of Mississippi Landfill Capacity In Relation To Waste Generation And Land-Use Constraints, Jason C. Anderson

Master's Theses

Municipal solid waste (MSW) management presents a growing challenge in Mississippi as population trends, socioeconomic change and regional development continue to place pressure on existing landfill capacity. This thesis examines waste generation and disposal patterns from 2000 through 2022 across Mississippi counties, with projections extending to 2050. Historical landfill tonnage data was gathered and compiled from the Mississippi Department of Environmental Quality (MDEQ) and analyzed using regression models in Excel and RStudio, with forecasts generated for both in-state and out-of-state waste flow. Results highlight significant variations among landfills, including differing closure timelines, changing county service areas and notable shifts in …

Quantifying Discard Mortality Of Undersized And Ovigerous Crabs In The Gulf Of Mexico Blue Crab Fishery, Micayla Cochran

Master's Theses

Blue crabs support a valuable commercial fishery in the Gulf of Mexico. Most states require the release of undersized and ovigerous blue crabs, yet mortality of these discarded crabs is an understudied component of total mortality. The first objective of this project was to quantify discard mortality of non-target crabs using bycatch surveys across the Lake Pontchartrain–Mississippi Sound coastal system. Ovigerous crabs were most common at high salinities and temperatures, whereas undersized crab presence was inversely correlated with soak time, temperature, and the number of crabs per trap, and also varied among geographic locations. A reflex action mortality prediction assessment …

Explaining The Gap: The Mediating Effect Of Basic Psychological Need Satisfaction On Parenting Styles And Disordered Eating Behaviors, Oliva Dixon

Master's Theses

Eating disorders remain one of the fastest growing and most fatal forms of mental health disorders. It is estimated that around 9% of the US population meets diagnostic criteria for an eating disorder; however, a much larger percentage of the population engages in disordered eating behaviors, putting people at risk for negative consequences both physically and psychologically. While there are several theories about what precipitates disordered eating, parenting has been shown to be a key factor that can influence disordered eating behaviors. While some theories implicate authoritarian parenting, others consider psychological control or permissive parenting as potentially associated with the …

Discerning Patterns Of Floral Sugar-Feeding: Dynamics Of The Mosquito Culex Antillummagnorum In Puerto Rico, Ella J. Branham

Master's Theses

Mosquitoes rely on sugar feeding for survival, primarily from flowering plants, yet mosquito–plant interactions remain understudied. I examined plant-feeding associations of the mosquito Culex antillummagnorum in the Luquillo Experimental Forest of Puerto Rico, which may clarify patterns of habitat use, disease dynamics, and broader species interactions. First, plant DNA was extracted from field-collected Cx. antillummagnorum to identify potential nectar sources. DNA barcoding produced positive matches to the flowering plant genera Billia, Aesculus, Cladium, Fimbristylis, Xyris, Cakile, and Habenaria. Habenaria was the most compelling result because it belongs to the same subtribe of orchids …

Redeveloping Mississippi: A Case Study On Brownfields In Central & Southern Mississippi, Sahrah R. Yeroozedek

Master's Theses

Brownfields, or properties that are or possibly are contaminated with dangerous materials, represent a common obstacle for communities in Mississippi. The real or potential presence of contaminants at these sites often deters investors due to costly cleanup requirements (EPA, n.d. -b). The Environmental Protection Agency (EPA), through its Brownfield Revitalization Program, implemented guidelines for covering the costs and labor associated with the remediation of these properties. The EPA is not, however, responsible for redevelopment that supports long-term environmental and economic sustainability. Although the EPA maintains inventories of all Brownfields, there is also no comprehensive database of Brownfields and their current …

An Assessment Of The Basihyal And Its Functional And Ontogenetic Relationships To The Masticatory Apparatus In Primates, Parker Mitchell Taylor

Graduate Theses and Dissertations

The hyoid is central to many important functions such as feeding, vocalization, and breathing. However, primate hyoid morphology has been widely understudied compared to other aspects of craniofacial morphology. This dissertation aimed to bridge gaps in the current understanding of primate hyoid morphological variation and the hyoid’s relationship with mandibular morphology. Using microCT, diceCT, and three-dimensional geometric morphometric methods, this work details broad taxonomic variation of basihyal shape, resting hyoid position, and suprahyoid muscle architecture in primates, and assesses such variation for the effects of phylogeny, allometry, and covariation between these elements and mandibular shape. These analyses were also conducted …

Exploring A 'Fishy' Solution: Uncovering Human Norovirus Using A Zebrafish Model, Sahaana Chandran

Graduate Theses and Dissertations

Human norovirus (HuNoV) is the leading cause of acute gastroenteritis worldwide; however, the lack of robust laboratory culture systems and reliable animal models has limited progress in understanding viral replication and developing effective intervention strategies. While alternative models such as the zebrafish system have been explored, gaps remain in evaluating their ability to support replication across diverse HuNoV strains and in identifying factors that influence infectivity. This dissertation provides a comprehensive investigation into the use of the zebrafish model for studying viral replication, host interactions, and potential inhibition strategies. Initial studies focused on optimizing viral delivery methods using Tulane virus …

Leveraging Historic Collections: Investigating Morphometric Differentiation In Members Of The Arisaema Triphyllum (L.) Schott (Araceae) Species Complex, Morgan Bradley Russell

Graduate Theses and Dissertations

The Jack-in-the-pulpit (Arisaema triphyllum (L.) Schott) is an herbaceous perennial herb of North America, and its taxonomic history is full of confusion and rank shifts. Now split into six species, the A. triphyllum species complex consists of morphologically similar taxa that have differing ploidy levels. In Chapter I, I compiled a detailed introduction and history for these taxa, focusing on their taxonomic complexity and morphological ambiguity in herbarium specimens and immature plants. I also presented their ploidy distinctions and how the implications of polyploidy may hold answers to parsing them apart, especially in dried herbarium specimens where defining characteristics are …

Bats And Bacteria: Infection Dynamics At The Human-Wildlife Interface, Isabella Katherine Deanglis

Graduate Theses and Dissertations

As the second most diverse mammalian order, bats host an array of pathogens, some of which are known to infect humans. Synanthropic bats share spaces with humans, resulting in bat-borne pathogen exposure. While most bat-borne disease research has focused on viral pathogens, bats host numerous bacterial pathogens with zoonotic potential. By integrating a global meta-analysis with field studies in Sub-Saharan Africa, I characterize the structural attributes that facilitate shared interfaces, the bacterial pathogens present in synanthropic bats of rural Kenya, and the physiological and environmental dynamics influencing odds of infection in these synanthropic bats. Finally, I evaluate the clinical relevance …

Dissecting The Complex Genomic Landscape Underlying Oxidative Stress Resistance Using Natural Variation In Yeast, Sonali Lakshika Anne Lenaduwe

Graduate Theses and Dissertations

Stress is experienced across the tree of life. Survival in fluctuating environments depends on a robust genetic architecture. This dissertation examines the genetic and metabolic determinants underlying one such adaptive response: cross-protection. Leveraging natural variation in the stress responses of budding yeast, Saccharomyces cerevisiae, I examine the genetic variation contributing to ethanol-induced cross-protection against oxidative stress. Acquired stress resistance, in which mild pre-exposure improves survival to subsequent stresses, is prevalent across diverse organisms and can involve both same-stress and cross-protection. Using high-throughput bulk segregant analysis (BSA-seq) and advanced intercross mapping populations derived from natural yeast isolates, I identify quantitative trait …

An Efficient Implementation Of Gibbs-Duhem Integration For Solid-Liquid Phase Coexistence In Binary Lennard-Jones System With Relevance To Aav Capsid Separation, Muhi Muntaka

Graduate Theses and Dissertations

Gene therapy using adeno-associated viruses (AAVs) holds promise for treating genetic diseases, but high manufacturing costs limit its widespread use. A major challenge is separating functional (full) AAV capsids from non-functional (empty) ones, which are produced in similar amounts and have nearly identical structures. Conventional purification methods, such as density gradient ultracentrifugation and chromatography, face drawbacks like low yield, poor scalability, and high cost, often requiring multi-step processes. Recently, selective crystallization has emerged as a promising alternative, offering improved efficiency, scalability, and product quality. However, optimizing this method requires a deep understanding of thermodynamic phase behavior in multicomponent systems. In …

Religion, Crime, And The Mediating Effects Of Social Control And Self-Control, Parker Bowman

Graduate Theses and Dissertations

Past research on the relationship between religion and crime has found the two variables have a significant negative correlation. Currently, there are two main mechanisms used to explain this relationship: social control and self-control. Social control theorists argue that participation in religious organizations decreases criminal behaviors by increasing social bonds. Self-control theorists argue that religious norms and values decrease criminal behavior by increasing an individual's self-control. While both mechanisms have been well supported by research, there remains the question of which is the stronger mediator of the religion-crime relationship. This study seeks to answer this question by comparing the effects …

Assessment Of Lake Water Quality Parameters Using Uav Hyperspectral Imaging, Hasanul Banna, Taufiqa Tajnin

Publications and Research

Monitoring water quality in lakes is critical for assessing ecosystem health, managing drinking water resources, and detecting harmful algal blooms. Unmanned Aerial Vehicle (UAV)–based hyperspectral imaging provides a promising approach for high-resolution observation of water quality parameters. In this undergraduate research project, hyperspectral imagery collected over sample lakes within the Delaware River Watershed was processed using BaySpec’s CubeStitcher software to assess its capability to detect variations in chlorophyll-a (Chl-a) concentrations. This work was conducted as part of a National Fish and Wildlife Foundation (NFWF)-funded project in collaboration with Princeton Hydro and NYC College of New York. Hyperspectral image cubes were …

Generations At Work: Examining Differences In The Nonprofit Sector, Cory J. Bergeron

Dissertations

This non-experimental quantitative dissertation examined generational differences among non-management employees in the United States nonprofit sector, where multiple generational cohorts work side by side. The problem addressed is that nonprofit leaders’ limited understanding of how distinct generational experiences shape employees’ work-related attitudes and preferences can contribute to conflict, reduced engagement, and costly turnover in already resource-constrained organizations. Grounded in Mannheim’s generational theory and Becker’s human capital theory, the study conceptualized generational cohorts as groups whose shared formative experiences influence what they value in their work context and how those values translate into human capital that affects organizational outcomes.

Using a …

Psychological And Inflammatory Ties To Diet In Breast Cancer Survivors, Sonal Kaur Johal

Master's Theses

Breast cancer is among the most prevalent forms of cancer and is a primary cause of death among women (Wang et al., 2020). Cancer patients experience higher levels of anxiety symptoms, depressive symptoms, and inflammation compared to non-cancer patients, which can predict a diminished quality of life but also contribute to higher mortality rates among cancer patients (Bortolato et al., 2016; Song et al., 2022). Diet has the potential to impact the manifestation of depressive and anxiety symptoms in both healthy individuals and those battling cancer. This study explored the association between dietary habits, specifically cholesterol, fiber, saturated fat, added …

Trailside Waste As An Indicator Of Human Impact: A Case Study Of The Lone Star Hiking Trail, Madison Slater

Theses & ETDs

Long-distance hiking trails provide important recreational and ecological benefits but are increasingly affected by recreation-derived waste. This study assessed the distribution and composition of litter along the 96-mile Lone Star Hiking Trail (LSHT) in the Sam Houston National Forest in the state of Texas. Using a complete trail census approach inspired by prior research on the Pacific Crest Trail (PCT), all encountered waste items were recorded, categorized, and assigned to one-mile transects to evaluate spatial patterns. A total of 327 items were documented, averaging 3.4 items per mile. Waste patterns demonstrated clear clustering near access points like that of trailheads …

Manatee Acoustic Detection: Adapting Cnn Models To New Locations, Vivian Cargille

Theses & ETDs

Automated detection of manatee vocalizations across a wide range of habitats, from coastal and estuarine systems to rivers and freshwater springs, is challenged by domain shift, the reduction in model performance when applied to acoustic conditions not represented in training data. We compiled a training dataset of 61,924 annotated clips (19,461 manatee vocalizations, 42,463 background noise) from seven locations spanning West Africa and Florida, including both African (Trichechus senegalensis) and American (Trichechus manatus) manatee vocalizations, and evaluated four Convolutional Neural Network architectures for binary vocalization detection. Leave-location-out cross-validation revealed substantial variation in cross-location generalization, with on-animal tag recordings producing the …

Return Of The Wolf: An Assessment Of The Reintroduction Of The Gray Wolves To Yellowstone National Park, Keagan Roeder

Theses & ETDs

This paper examines the reintroduction of gray wolves to Yellowstone National Park by breaking the topic into several sections. It begins with an introduction and a history and timeline section, which provide background on wolf eradication and the events leading up to their reintroduction in 1995–1996. The paper then moves into legal sections, including discussions of the Endangered Species Act, the Environmental Impact Statement, and key court cases, explaining how policy and law made the reintroduction possible and continue to shape wolf management. Ecological impacts are explored in sections focused on animal populations and behavior, waterways, and plant communities, highlighting …

Time Is A Tree: Arboreal Chronotopes & Reciprocal Dendrochronology, Alyssa Bernard

Theses & ETDs

This thesis proposes a framework for reciprocal dendrochronology, a decolonial approach to tree-ring science that shifts the role of the researcher from an extractive observer to a vessel for translating arboreal memory, and explores how trees function as chronotopes: material intersections where time and space are fused into a living record (Bakhtin 1981). By applying the structuralist frameworks of Claude Lévi-Strauss (1955) and Joseph Campbell (1949), it is argued that trees have long functioned as universal symbols of continuity and the axis of existence. This baseline is then brought into conversation with the chronotopic theory of Mikhail Bakhtin (1981) and …

Reproductive Characteristics Of The Chain Pipefish, Syngnathus Louisianae, David Kelley

Theses & ETDs

Syngnathids: pipefish, seahorses, and seadragons in the family Syngnathidae, are an evolutionarily unique, yet often understudied group of species typically found in shallow seagrass habitats, defined by their collection of extremely specialized adaptations, which include but are not limited to: male pregnancy, elongated and rigid bodies with bony plates, small fins not well suited for swimming, and fused jaws that form long and thin snouts. This study examines the species Syngnathus louisianae, a large pipefish native to coastal waters, namely seagrass and sargassum habitats, in the Gulf of Mexico and Atlantic Coast. This species was chosen for this study over …

Back To The Bayfront, Dania Hefley

Theses & ETDs

I’m trying to make sense of the different versions of myself that existed inside New College over the last four years. How I existed while studying. Which classrooms made me feel like a person. Which professors taught me how to read. Which ones taught me how to think. Which ones made me want to rise to the level of the room. Which ones made me feel like I was disappearing. I don’t want to turn these four years into a lesson, but I need a way in that lets me see the throughline. Recently, my literature professor, Miller, was talking …

Understanding Tlr3 Immune Response Activation In Cryptosporidium Parvum And Cryspovirus Pathogenesis, Surayya Hudayberganova

Biochemistry and Molecular Biology

Cryptosporidiosis is a serious gastrointestinal illness caused by a protozoan parasite known as Cryptosporidium. It is particularly dangerous for malnourished children and those with compromised immune systems. My research focuses on the Toll-like receptor 3 (TLR3) response to the Cryptosporidium parvum infection, specifically in the presence of the parasite’s viral mutualist named cryspovirus (CSpV1). Results using research methodologies like ELISA and RT-qPCR have indicated that TLR3 expression increases during the infection process of Cryptosporidium parvum (C. parvum). Furthermore, one intriguing observation concluded during this study suggests that administering the TLR3-specific inhibitor CU-CPT4a to infected cells drastically decreased this activation. This …

Synthesis And Characterization Of Bis(Pyrazolate) Metal-Organic Frameworks For Carbon Dioxide Adsorption And Sequestration, Emily Granville

Theses & ETDs

There has been an increase in carbon dioxide (CO2) emissions into the atmosphere due to the burning of fossil fuels for energy, vehicle transportation, industrial factories, and deforestation. This is harmful to the environment as it is the primary factor of climate change and ocean acidification. To help solve this issue, scientists have been using metal-organic frameworks (MOFs) to adsorb and sequester the CO2 due to the highly porous crystalline structures and open metal sites of the MOFs. Hard metal cations act as hard Lewis acids that would coordinate in the open metal site, which attracts the lone pair on …