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2022

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Impairment Of Igg Fc Functions Promotes Tumor Progression And Suppresses Nk Cell Antitumor Actions, Xuejun Fan, Zihao Yuan, Yueshui Zhao, Wei Xiong, Hao-Ching Hsiao, Rahmawati Pare, Jianmin Ding, Ahmad Almosa, Kai Sun, Songlin Zhang, Robert E Jordan, Cheok Song Lee, Zhiqiang An, Ningyan Zhang Sep 2022

Impairment Of Igg Fc Functions Promotes Tumor Progression And Suppresses Nk Cell Antitumor Actions, Xuejun Fan, Zihao Yuan, Yueshui Zhao, Wei Xiong, Hao-Ching Hsiao, Rahmawati Pare, Jianmin Ding, Ahmad Almosa, Kai Sun, Songlin Zhang, Robert E Jordan, Cheok Song Lee, Zhiqiang An, Ningyan Zhang

Faculty, Staff and Student Publications

Natural killer (NK) cells mediate antibody dependent cytotoxic killing of cancer cells via cross-linking FcγR on NK cells with IgG-Fc. Studies have shown that the single-hinge cleaved IgGs (scIgGs) have dysfunctional Fc and failed engagement with FcγRs on immune cells. However, little is known about how scIgGs impact on antitumor immunity in the tumor microenvironment. In this study, we revealed a significant association of tumor scIgGs with tumor progression and poor outcomes of breast cancer patients (n = 547). Using multiple mouse tumor models, we demonstrated that tumor scIgGs reduced NK cell cytotoxic activities and resulted in aggressive tumor progression. …


A Blind Benchmark Of Analysis Tools To Infer Kinetic Rate Constants From Single-Molecule Fret Trajectories, Dorothy A. Erie, Lydia Kisley, Dushani Dunukara Sep 2022

A Blind Benchmark Of Analysis Tools To Infer Kinetic Rate Constants From Single-Molecule Fret Trajectories, Dorothy A. Erie, Lydia Kisley, Dushani Dunukara

Faculty Scholarship

Single-molecule FRET (smFRET) is a versatile technique to study the dynamics and function of biomolecules since it makes nanoscale movements detectable as fluorescence signals. The powerful ability to infer quantitative kinetic information from smFRET data is, however, complicated by experimental limitations. Diverse analysis tools have been developed to overcome these hurdles but a systematic comparison is lacking. Here, we report the results of a blind benchmark study assessing eleven analysis tools used to infer kinetic rate constants from smFRET trajectories. We test them against simulated and experimental data containing the most prominent difficulties encountered in analyzing smFRET experiments: different noise …


Identification Of Risk Genes For Alzheimer’S Disease By Gene Embedding, Yashwanth Lagisetty, Thomas Bourquard, Ismael Al-Ramahi, Carl Grant Mangleburg, Samantha Mota, Shirin Soleimani, Joshua M Shulman, Juan Botas, Kwanghyuk Lee, Olivier Lichtarge Sep 2022

Identification Of Risk Genes For Alzheimer’S Disease By Gene Embedding, Yashwanth Lagisetty, Thomas Bourquard, Ismael Al-Ramahi, Carl Grant Mangleburg, Samantha Mota, Shirin Soleimani, Joshua M Shulman, Juan Botas, Kwanghyuk Lee, Olivier Lichtarge

Duncan NRI Faculty and Staff Publications

Most disease-gene association methods do not account for gene-gene interactions, even though these play a crucial role in complex, polygenic diseases like Alzheimer’s disease (AD). To discover new genes whose interactions may contribute to pathology, we introduce GeneEMBED. This approach compares the functional perturbations induced in gene interaction network neighborhoods by coding variants from disease versus healthy subjects. In two independent AD cohorts of 5,169 exomes and 969 genomes, GeneEMBED identified novel candidates. These genes were differentially expressed in post mortem AD brains and modulated neurological phenotypes in mice. Four that were differentially overexpressed and modified neurodegeneration in vivo are …


Butte Priority Soils Operable Unit (Bpsou) Final Insufficiently Reclaimed Sites - Field Sampling Plan (Fsp) Bres No. 158 - Waste Rock Dump, Mike Mcanulty Sep 2022

Butte Priority Soils Operable Unit (Bpsou) Final Insufficiently Reclaimed Sites - Field Sampling Plan (Fsp) Bres No. 158 - Waste Rock Dump, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Farmyard Animal Or Best Friend? Exploring Predictors Of Dog Vs. Pig Pet Speciesism, Sarah Gradidge, Magdalena Zawisza, Annelie J. Harvey, Daragh T. Mcdermott Sep 2022

Farmyard Animal Or Best Friend? Exploring Predictors Of Dog Vs. Pig Pet Speciesism, Sarah Gradidge, Magdalena Zawisza, Annelie J. Harvey, Daragh T. Mcdermott

People and Animals: The International Journal of Research and Practice

Despite dogs’ and pigs’ shared similarities, previous research indicates people favor dogs over pigs (known as “pet speciesism”). While pet speciesism has been empirically sup-ported, little is known about its predictors. This gap in the literature is problematic as urgent requirements to decrease meat consumption emphasize the pressing need to develop interventions to reduce pet speciesism and thus reduce meat consumption. However, to develop these interventions, we must first identify why people view pigs (vs. dogs) negatively. To begin addressing this gap, the current study utilized the stereotype content model to uniquely explore pet speciesism’s predictors. We recruited participants via …


Making The Case: Adding A Social Work Perspective To A Case Study In A Veterinary Practice, Paula Gerstenblatt, Diane Rhodes, Dorothea Ivey Sep 2022

Making The Case: Adding A Social Work Perspective To A Case Study In A Veterinary Practice, Paula Gerstenblatt, Diane Rhodes, Dorothea Ivey

People and Animals: The International Journal of Research and Practice

This article describes a case study exploration of a veterinary practice from the perspective of social work. Recognizing the stressful work of veterinary providers, including compassion fatigue and high suicide rates, the current study identified both a need for and the potential role of social workers in veterinary practice. Professionals were interviewed in an emergency/specialty practice. Using the interview data, the authors built a demonstrative case that underlines the vulnerability of veterinary professionals and the potential of social work to improve the quality of their work experiences and longevity.


Recent Findings On Phosphorus Digestibility Of Feed Ingredients In Broilers, Jay Hampton, Wenting Li, Franco Mussini, Katie Hilton, Janet Remus, Samuel J. Rochell Sep 2022

Recent Findings On Phosphorus Digestibility Of Feed Ingredients In Broilers, Jay Hampton, Wenting Li, Franco Mussini, Katie Hilton, Janet Remus, Samuel J. Rochell

Proceedings of the Arkansas Nutrition Conference

Accurately meeting the dietary P needs of broilers is critical to ensure optimal bird performance, health, and welfare without causing undue environmental burdens associated with excess dietary P excretion. Phosphorus is commonly supplied in broiler diets from inorganic phosphates derived from non-renewable sources, but it has been estimated that peak P production will occur between 2030-2040 and that the global supply of P could be depleted within this century (Cordell and Drangert, 2009; Nest and Cordell, 2012). To address these concerns, inorganic P use in agriculture, including use in broiler diet formulation, requires careful stewardship. To this end, the dietary …


Interannual Variability In Methane And Nitrous Oxide Concentrations And Sea-Air Fluxes Across The North American Arctic Ocean (2015–2019), Cara C. M. Manning, Zhiyin Zheng, Lindsay Fenwick, Ross D. Mcculloch, Ellen Damm, Robert W. Izett, William J. Williams, Sarah Zimmermann, Svein Vagle, Philippe D. Tortell Sep 2022

Interannual Variability In Methane And Nitrous Oxide Concentrations And Sea-Air Fluxes Across The North American Arctic Ocean (2015–2019), Cara C. M. Manning, Zhiyin Zheng, Lindsay Fenwick, Ross D. Mcculloch, Ellen Damm, Robert W. Izett, William J. Williams, Sarah Zimmermann, Svein Vagle, Philippe D. Tortell

Department of Marine Sciences

Between 2015 and 2018, we collected approximately 2,000 water column measurements of methane (CH4) and nitrous oxide (N2O) concentrations in the North American Arctic Ocean during summer and early fall. We also obtained 25 measurements of CH4 and N2O concentrations in rivers along the Northwest Passage and Ellesmere Island in midsummer 2017–2019. Our results show that N2O is generated in the highly productive Bering and Chukchi Seas and transported northeastward, producing a persistent subsurface N2O peak in the Beaufort Sea. The Chukchi and Beaufort Sea sediments are a significant …


Pulse-Echo Quantitative Us Biomarkers For Liver Steatosis: Toward Technical Standardization, Timothy Stiles, David T. Fetzer, Ivan M. Rosado-Mendez, Michael Wang, Michelle L. Robbin, Arinc Ozturk, Keith A. Wear, Juvenal Ormachea, J. Brian Fowlkes, Timothy J. Hall, Anthony E. Samir Sep 2022

Pulse-Echo Quantitative Us Biomarkers For Liver Steatosis: Toward Technical Standardization, Timothy Stiles, David T. Fetzer, Ivan M. Rosado-Mendez, Michael Wang, Michelle L. Robbin, Arinc Ozturk, Keith A. Wear, Juvenal Ormachea, J. Brian Fowlkes, Timothy J. Hall, Anthony E. Samir

Natural Sciences Publications

Excessive liver fat (steatosis) is now the most common cause of chronic liver disease worldwide and is an independent risk factor for cirrhosis and associated complications. Accurate and clinically useful diagnosis, risk stratification, prognostication, and therapy monitoring require accurate and reliable biomarker measurement at acceptable cost. This article describes a joint effort by the American Institute of Ultrasound in Medicine (AIUM) and the RSNA Quantitative Imaging Biomarkers Alliance (QIBA) to develop standards for clinical and technical validation of quantitative biomarkers for liver steatosis. The AIUM Liver Fat Quantification Task Force provides clinical guidance, while the RSNA QIBA Pulse-Echo Quantitative Ultrasound …


Faculty Senate Subcommittees, 2022-2023, University Of Mississippi. Faculty Senate Sep 2022

Faculty Senate Subcommittees, 2022-2023, University Of Mississippi. Faculty Senate

Membership

A list of the University of Mississippi Faculty Senate subcommittees and their members for the 2021-2022 academic year.


Faculty Senate Membership, 2022-2023, University Of Mississippi. Faculty Senate Sep 2022

Faculty Senate Membership, 2022-2023, University Of Mississippi. Faculty Senate

Membership

A list of officers, committee chairs, and senators of the University of Mississippi Faculty Senate for the 2022-2023 academic year.


Epitaxial Self-Assembly Of Interfaces Of 2d Metal–Organic Frameworks For Electroanalytical Detection Of Neurotransmitters, Robert M. Stolz, Anna F. Kolin, Brunno C. Rocha, Anna Brinks, Aileen M. Eagleton, Lukasz Mendecki, Harish Vashisth, Katherine A. Mirica Sep 2022

Epitaxial Self-Assembly Of Interfaces Of 2d Metal–Organic Frameworks For Electroanalytical Detection Of Neurotransmitters, Robert M. Stolz, Anna F. Kolin, Brunno C. Rocha, Anna Brinks, Aileen M. Eagleton, Lukasz Mendecki, Harish Vashisth, Katherine A. Mirica

New Hampshire EPSCoR

This paper identifies the electrochemical properties of individual facets of anisotropic layered conductive metal–organic frameworks (MOFs) based on M3(2,3,6,7,10,11-hexahydroxytriphenylene)2 (M3(HHTP)2) (M = Co, Ni). The electroanalytical advantages of each facet are then applied toward the electrochemical detection of neurochemicals. By employing epitaxially controlled deposition of M3(HHTP)2 MOFs on electrodes, the contribution of the basal plane ({001} facets) and edge sites ({100} facets) of these MOFs can be individually determined using electrochemical characterization techniques. Despite having a lower observed heterogeneous electron transfer rate constant, the {001} facets of the M3(HHTP)2 systems prove more selective and sensitive for the detection of dopamine …


Apolipoprotein E4 Impairs The Response Of Neurodegenerative Retinal Microglia And Prevents Neuronal Loss In Glaucoma, Milica A. Margeta, Zhuoran Yin, Charlotte Madore, Kristen M. Pitts, Sophia M. Letcher, Jing Tang, Shuhong Jiang, Christian D. Gauthier, Sebastian R. Silveira, Caitlin M. Schroeder, Eleonora M. Lad, A D. Proia, Rudolph E. Tanzi, David M. Holtzman, Susanne Krasemann, Dong Feng Chen, Oleg Butovsky Sep 2022

Apolipoprotein E4 Impairs The Response Of Neurodegenerative Retinal Microglia And Prevents Neuronal Loss In Glaucoma, Milica A. Margeta, Zhuoran Yin, Charlotte Madore, Kristen M. Pitts, Sophia M. Letcher, Jing Tang, Shuhong Jiang, Christian D. Gauthier, Sebastian R. Silveira, Caitlin M. Schroeder, Eleonora M. Lad, A D. Proia, Rudolph E. Tanzi, David M. Holtzman, Susanne Krasemann, Dong Feng Chen, Oleg Butovsky

Osteopathic Medicine, Jerry M. Wallace School of

The apolipoprotein E4 (APOE4) allele is associated with an increased risk of Alzheimer disease and a decreased risk of glaucoma, but the underlying mechanisms remain poorly understood. Here, we found that in two mouse glaucoma models, microglia transitioned to a neurodegenerative phenotype characterized by upregulation of Apoe and Lgals3 (Galectin-3), which were also upregulated in human glaucomatous retinas. Mice with targeted deletion of Apoe in microglia or carrying the human APOE4 allele were protected from retinal ganglion cell (RGC) loss, despite elevated intraocular pressure (IOP). Similarly to Apoe retinal microglia, APOE4-expressing microglia did not upregulate neurodegeneration-associated genes, including Lgals3, following …


Uab Mhrc Celebrates 20 Years With Name Change To Uab Minority Health And Health Equity Research Center, Staff Sep 2022

Uab Mhrc Celebrates 20 Years With Name Change To Uab Minority Health And Health Equity Research Center, Staff

Browse All News

No abstract provided.


Defective Rab31-Mediated Megakaryocytic Early Endosomal Trafficking Of Vwf, Egfr, And M6pr In Runx1 Deficiency, Gauthami Jalagadugula, Guangfen Mao, Lawrence E Goldfinger, Jeremy Wurtzel, Fabiola Del Carpio-Cano, Michele P Lambert, Brian Estevez, Deborah L French, Mortimer Poncz, A Koneti Rao Sep 2022

Defective Rab31-Mediated Megakaryocytic Early Endosomal Trafficking Of Vwf, Egfr, And M6pr In Runx1 Deficiency, Gauthami Jalagadugula, Guangfen Mao, Lawrence E Goldfinger, Jeremy Wurtzel, Fabiola Del Carpio-Cano, Michele P Lambert, Brian Estevez, Deborah L French, Mortimer Poncz, A Koneti Rao

Cardeza Foundation for Hematologic Research

Transcription factor RUNX1 is a master regulator of hematopoiesis and megakaryopoiesis. RUNX1 haplodeficiency (RHD) is associated with thrombocytopenia and platelet granule deficiencies and dysfunction. Platelet profiling of our study patient with RHD showed decreased expression of RAB31, a small GTPase whose cell biology in megakaryocytes (MKs)/platelets is unknown. Platelet RAB31 messenger RNA was decreased in the index patient and in 2 additional patients with RHD. Promoter-reporter studies using phorbol 12-myristate 13-acetate-treated megakaryocytic human erythroleukemia cells revealed that RUNX1 regulates RAB31 via binding to its promoter. We investigated RUNX1 and RAB31 roles in endosomal dynamics using immunofluorescence staining for markers of …


Icc Approved Courses 9-13-22, Angela Brock Sep 2022

Icc Approved Courses 9-13-22, Angela Brock

Individual Course Committee (ICC)

No abstract provided.


Icc Agenda 9-13-22, Angela Brock Sep 2022

Icc Agenda 9-13-22, Angela Brock

Individual Course Committee (ICC)

No abstract provided.


Mesures À Haute Sensibilité Du Passage De Contaminants Nanométriques À Travers Les Gants De Protection Par Imagerie Médicale, Mahmoud Mohamed Omar, Amélie Augé, Myriam Laprise-Pelletier, Ludovic Tuduri, Marc-André Fortin Sep 2022

Mesures À Haute Sensibilité Du Passage De Contaminants Nanométriques À Travers Les Gants De Protection Par Imagerie Médicale, Mahmoud Mohamed Omar, Amélie Augé, Myriam Laprise-Pelletier, Ludovic Tuduri, Marc-André Fortin

Rapports de recherche scientifique

Les gants de polymère sont utilisés comme équipements de protection individuels dans de nombreux secteurs d’activité professionnelle où les risques chimiques sont présents. Leur efficacité à bloquer le passage de certains contaminants doit être mesurée par des méthodes d’essais précises et standardisées. Les mesures de résistance chimique sont généralement effectuées en utilisant une cellule de perméation, un petit appareil contenant deux réservoirs séparés par la membrane dont on veut mesurer le potentiel-barrière : l’un contient le contaminant, l’autre contient un milieu collectant le contaminant après que celui-ci ait passé à travers la membrane. Au fur et à mesure de l’expérience, …


Pest Population Dynamics Are Related To A Continental Overwintering Gradient, Douglas Lawton, Anders S. Huseth, George G. Kennedy, Amy C. Morey, William D. Hutchison, Dominic D. Reisig, Seth J. Dorman, De Shae Dillard, Robert C. Venette, Russell L. Groves, John J. Adamczyk, Izailda Barbosa Dos Santos, Tracey Baute, Sebe Brown, Eric Burkness, Ashley Dean, Galen P. Dively, Hélène B. Doughty, Shelby J. Fleischer, Jessica Green, Jeremy K. Greene, Krista Hamilton, Erin Hodgson, Thomas Hunt, David Kerns, Billy Rogers Leonard, Sean Malone, Fred Musser, David Owens, John C. Palumbo, Silvana Paula-Moraes, Julie A. Peterson, Ricardo Ramirez Sep 2022

Pest Population Dynamics Are Related To A Continental Overwintering Gradient, Douglas Lawton, Anders S. Huseth, George G. Kennedy, Amy C. Morey, William D. Hutchison, Dominic D. Reisig, Seth J. Dorman, De Shae Dillard, Robert C. Venette, Russell L. Groves, John J. Adamczyk, Izailda Barbosa Dos Santos, Tracey Baute, Sebe Brown, Eric Burkness, Ashley Dean, Galen P. Dively, Hélène B. Doughty, Shelby J. Fleischer, Jessica Green, Jeremy K. Greene, Krista Hamilton, Erin Hodgson, Thomas Hunt, David Kerns, Billy Rogers Leonard, Sean Malone, Fred Musser, David Owens, John C. Palumbo, Silvana Paula-Moraes, Julie A. Peterson, Ricardo Ramirez

Faculty Publications

Overwintering success is an important determinant of arthropod populations that must be considered as climate change continues to influence the spatiotemporal population dynamics of agricultural pests. Using a long-term monitoring database and biologically relevant overwintering zones, we modeled the annual and seasonal population dynamics of a common pest, Helicoverpa zea (Boddie), based on three overwintering suitability zones throughout North America using four decades of soil temperatures: the southern range (able to persist through winter), transitional zone (uncertain overwintering survivorship), and northern limits (unable to survive winter). Our model indicates H. zea population dynamics are hierarchically structured with continental-level effects that …


The Matricellular Protein Sparc Induces Inflammatory Interferon-Response In Macrophages During Aging, Seungjin Ryu, Sviatoslav Sidorov, Eric Ravussin, Maxim Artyomov, Akiko Iwasaki, Andrew Wang, Vishwa Deep Dixit Sep 2022

The Matricellular Protein Sparc Induces Inflammatory Interferon-Response In Macrophages During Aging, Seungjin Ryu, Sviatoslav Sidorov, Eric Ravussin, Maxim Artyomov, Akiko Iwasaki, Andrew Wang, Vishwa Deep Dixit

Clinical Research Faculty Publications

The risk of chronic diseases caused by aging is reduced by caloric restriction (CR)-induced immunometabolic adaptation. Here, we found that the matricellular protein, secreted protein acidic and rich in cysteine (SPARC), was inhibited by 2 years of 14% sustained CR in humans and elevated by obesity. SPARC converted anti-inflammatory macrophages into a pro-inflammatory phenotype with induction of interferon-stimulated gene (ISG) expression via the transcription factors IRF3/7. Mechanistically, SPARC-induced ISGs were dependent on toll-like receptor-4 (TLR4)-mediated TBK1, IRF3, IFN-β, and STAT1 signaling without engaging the Myd88 pathway. Metabolically, SPARC dampened mitochondrial respiration, and inhibition of glycolysis abrogated ISG induction by SPARC …


September 13, 2022 Ereporter, University Of Alabama At Birmingham Sep 2022

September 13, 2022 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Serpinb3 Drives Cancer Stem Cell Survival In Glioblastoma, Adam Lauko, Josephine Volovetz, Soumya M Turaga, Defne Bayik, Daniel J Silver, Kelly Mitchell, Erin E Mulkearns-Hubert, Dionysios C Watson, Kiran Desai, Manav Midha, Jing Hao, Kathleen Mccortney, Alicia Steffens, Ulhas Naik, Manmeet S Ahluwalia, Shideng Bao, Craig Horbinski, Jennifer S Yu, Justin D Lathia Sep 2022

Serpinb3 Drives Cancer Stem Cell Survival In Glioblastoma, Adam Lauko, Josephine Volovetz, Soumya M Turaga, Defne Bayik, Daniel J Silver, Kelly Mitchell, Erin E Mulkearns-Hubert, Dionysios C Watson, Kiran Desai, Manav Midha, Jing Hao, Kathleen Mccortney, Alicia Steffens, Ulhas Naik, Manmeet S Ahluwalia, Shideng Bao, Craig Horbinski, Jennifer S Yu, Justin D Lathia

Department of Medicine Faculty Papers

Despite therapeutic interventions for glioblastoma (GBM), cancer stem cells (CSCs) drive recurrence. The precise mechanisms underlying CSC resistance, namely inhibition of cell death, are unclear. We built on previous observations that the high cell surface expression of junctional adhesion molecule-A drives CSC maintenance and identified downstream signaling networks, including the cysteine protease inhibitor SerpinB3. Using genetic depletion approaches, we found that SerpinB3 is necessary for CSC maintenance, survival, and tumor growth, as well as CSC pathway activation. Knockdown of SerpinB3 also increased apoptosis and susceptibility to radiation therapy. SerpinB3 was essential to buffer cathepsin L-mediated cell death, which was enhanced …


Approved Programs 9-13-22, Angela Brock Sep 2022

Approved Programs 9-13-22, Angela Brock

Programs Committee (PC)

No abstract provided.


Programs Committee Agenda 9-13-22, Angela Brock Sep 2022

Programs Committee Agenda 9-13-22, Angela Brock

Programs Committee (PC)

No abstract provided.


Food-Borne Chemical Carcinogens And The Evidence For Human Cancer Risk, Tetyana Kobets, Benjamin P C Smith, Gary M Williams Sep 2022

Food-Borne Chemical Carcinogens And The Evidence For Human Cancer Risk, Tetyana Kobets, Benjamin P C Smith, Gary M Williams

NYMC Faculty Publications

Commonly consumed foods and beverages can contain chemicals with reported carcinogenic activity in rodent models. Moreover, exposures to some of these substances have been associated with increased cancer risks in humans. Food-borne carcinogens span a range of chemical classes and can arise from natural or anthropogenic sources, as well as form endogenously. Important considerations include the mechanism(s) of action (MoA), their relevance to human biology, and the level of exposure in diet. The MoAs of carcinogens have been classified as either DNA-reactive (genotoxic), involving covalent reaction with nuclear DNA, or epigenetic, involving molecular and cellular effects other than DNA reactivity. …


Metasurfaces For Sensing Applications: Gas, Bio And Chemical, Shawana Tabassum, S.K. Nayemuzzaman, Manish Kala, Akhilesh Kumar Mishra, Satyendra Kumar Mishra Sep 2022

Metasurfaces For Sensing Applications: Gas, Bio And Chemical, Shawana Tabassum, S.K. Nayemuzzaman, Manish Kala, Akhilesh Kumar Mishra, Satyendra Kumar Mishra

Electrical Engineering Faculty Publications and Presentations

Performance of photonic devices critically depends upon their efficiency on controlling the flow of light therein. In the recent past, the implementation of plasmonics, two-dimensional (2D) materials and metamaterials for enhanced light-matter interaction (through concepts such as sub-wavelength light confinement and dynamic wavefront shape manipulation) led to diverse applications belonging to spectroscopy, imaging and optical sensing etc. While 2D materials such as graphene, MoS2 etc., are still being explored in optical sensing in last few years, the application of plasmonics and metamaterials is limited owing to the involvement of noble metals having a constant electron density. The capability of competently …


Changing Stem To Steam: An Analyzation On The Effects Of Art Integration Up To The University Level, Elizabeth Richmond Sep 2022

Changing Stem To Steam: An Analyzation On The Effects Of Art Integration Up To The University Level, Elizabeth Richmond

Honors Projects

This Honors Project is a combination of an artistic, creative project and a research driven analysis. The focus of this project is to research and understand the effects the arts have on both general students and STEM students in particular, what benefits come from art education and art integration, and if STEM students benefit from art integration. This goal was accomplished through a literature review and annotated bibliography featuring 18 sources. Another goal of the project was to understand where I fit into the research. In my creative portion of the project, I explored and analyzed how the arts affected …


Thermodynamic Limits Of Atmospheric Water Harvesting, Akshay K. Rao, Andrew J. Fix, Yun Chi Yang, David M. Warsinger Sep 2022

Thermodynamic Limits Of Atmospheric Water Harvesting, Akshay K. Rao, Andrew J. Fix, Yun Chi Yang, David M. Warsinger

School of Mechanical Engineering Faculty Publications

Atmospheric water harvesting (AWH) is a rapidly emerging approach for decentralized water production, but current technology is limited by trade-offs between energy consumption and yield. The field lacks a common basis to compare different AWH technologies and a robust understanding of the performance impacts of water recovery, desorption humidity (for sorbent systems), and realistic component-level efficiencies. By devising a set of unifying assumptions and consistent parameters across technologies, we provide the first fair thermodynamic comparison over a broad range of environmental conditions. Using 2nd law analysis, or least work, we study the maximum efficiency for common open system AWH methods …


Evaluation Of Machine Learning Algorithm On Drinking Water Quality For Better Sustainability, Sanaa Kaddoura Sep 2022

Evaluation Of Machine Learning Algorithm On Drinking Water Quality For Better Sustainability, Sanaa Kaddoura

All Works

Water has become intricately linked to the United Nations' sixteen sustainable development goals. Access to clean drinking water is crucial for health, a fundamental human right, and a component of successful health protection policies. Clean water is a significant health and development issue on a national, regional, and local level. Investments in water supply and sanitation have been shown to produce a net economic advantage in some areas because they reduce adverse health effects and medical expenses more than they cost to implement. However, numerous pollutants are affecting the quality of drinking water. This study evaluates the efficiency of using …


Program Review Report 9-13-22, Angela Brock Sep 2022

Program Review Report 9-13-22, Angela Brock

Program Review Committee

No abstract provided.