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2022

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Investigation Of Pitching And Plunging Motions On A Tandem Wing Configuration, Riley M. Capiro Jan 2022

Investigation Of Pitching And Plunging Motions On A Tandem Wing Configuration, Riley M. Capiro

Honors Undergraduate Theses

From the beginning of the history of flight, inspiration has been drawn from nature. Evolution has spent millions of years optimizing creatures that rely on flight as their means of locomotion. Today, aerial vehicles are very different to those from the time of the Wright brothers. One kind of vehicle that stands to benefit in mimicking nature is the drone, particularly smaller drones. Commonly used today by militaries, industry and civilians, drones are increasingly affordable while also decreasing in size thanks to advancements in electronics and manufacturing methods. The purpose of this thesis is to investigate how pitching and rolling …

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Mental Health Of Puerto Ricans Who Stayed In Puerto Rico Compared To Those Who Migrated To Florida After Hurricane Maria, Sophia Chapdelaine Jan 2022

Mental Health Of Puerto Ricans Who Stayed In Puerto Rico Compared To Those Who Migrated To Florida After Hurricane Maria, Sophia Chapdelaine

Honors Undergraduate Theses

September 20th, 2017 was a devastating day for many Puerto Ricans as Hurricane Maria made landfall in Puerto Rico. A majority of people were left without electricity, water, transportation, and communication between friends and family. In addition, many experienced losses such as destruction of their home and personal belongings as well as the death of family members and friends. This resulted in a decline in mental health. According to previous literature, key indicators of poor mental health in Puerto Rico after Hurricane Maria were increased diagnoses of depression, anxiety, and Post Traumatic Stress Disorder (PTSD). This study provides a comprehensive …

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A Mixed Methods Study On Levels Of Physical Activity And Degree Of Fear Of Falling In Older Adults, Oscar L. Garcia Jan 2022

A Mixed Methods Study On Levels Of Physical Activity And Degree Of Fear Of Falling In Older Adults, Oscar L. Garcia

Honors Undergraduate Theses

Maintaining a physically active lifestyle has shown to decrease the risks of falling by slowing down the degenerative changes that occur with aging adults. But despite these physical changes, research has recognized the development of the fear of falling (FOF) as also attributing to the aging adults’ risk of falling. Furthermore, increases the risk of falling and subsequently increases the loss of independency. This study aimed to: 1) examine the relationships between the levels of physical activity, degree of FOF, and fall risk using quantitative approach; and 2) explore the changes of FOF and understand its cause using qualitative approach. …

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Genetic Algorighm Representation Selection Impact On Binary Classification Problems, Stephen V. Maldonado Jan 2022

Genetic Algorighm Representation Selection Impact On Binary Classification Problems, Stephen V. Maldonado

Honors Undergraduate Theses

In this thesis, we explore the impact of problem representation on the ability for the genetic algorithms (GA) to evolve a binary prediction model to predict whether a physical therapist is paid above or below the median amount from Medicare. We explore three different problem representations, the vector GA (VGA), the binary GA (BGA), and the proportional GA (PGA). We find that all three representations can produce models with high accuracy and low loss that are better than Scikit-Learn’s logistic regression model and that all three representations select the same features; however, the PGA representation tends to create lower weights …

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The Relationship Between Inflammatory Diet Score And Cancer Outcomes: Systematic Review And Meta-Analysis, Eric Han Jan 2022

The Relationship Between Inflammatory Diet Score And Cancer Outcomes: Systematic Review And Meta-Analysis, Eric Han

Honors Undergraduate Theses

Cancer remains one of the most prevalent diseases in the United States and a leading cause of death. Large prospective studies have found significant correlations between dietary intake and cancer. Chronic inflammation promotes pro-cancer inflammatory environments promoting the formation and growth of tumors while preventing effective anti-tumor responses. Nutrition can impact inflammation, with the intake of certain food items increasing biomarkers for systemic inflammation thus, the objective of this research was to explore the relationship between inflammatory diet score measured by the Dietary Inflammatory index and all-cause mortality, cancer-specific mortality, and cancer recurrence among cancer survivors. Web of Science, Medline, …

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Surviving Festival Disruptions : The Transformation Of The New Life | Performance Cultural Ecosystem In Contemporary Bangkok Due To The 2020 Covid-19 Pandemic, Pornrat Damrhung Jan 2022

Surviving Festival Disruptions : The Transformation Of The New Life | Performance Cultural Ecosystem In Contemporary Bangkok Due To The 2020 Covid-19 Pandemic, Pornrat Damrhung

Journal of Urban Culture Research

This article examines how COVID-19 disrupted the Life | Performance festival in Bangkok in 2020; focusing on changes in three festival components. Viewing the festival as a cultural ecosystem interrupted by the 2020 novel coronavirus, the article will focus on the disruptions forced on three pieces: Eko Supriyanto’s Urban Movement Laboratory, Gecko Parade’s Lindbergh’s Flight and Pichet Klunchun’s No. 60: Exhibition, Lecture | Demonstration. The pandemic-induced disruptions in these performances highlight several important ways that the COVID-19 pandemic transformed the Life | Performance urban festival. Changes occurred in the timing/scheduling, spacing/location, relationship with audiences/viewers and their mode of performance for …

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City Of The Future Theories : A Diachronic Comparative Study, Gildis Tachir, Ayşe Nilay Evcil Jan 2022

City Of The Future Theories : A Diachronic Comparative Study, Gildis Tachir, Ayşe Nilay Evcil

Journal of Urban Culture Research

This paper strives to interpret the future city or the future of the city by searching published articles. To do this, a review of literature had been made and articles from urban planning and architecture perspectives were studied. We collected information on the time-varying indicators that make up the cities of the future. In this study, it is investigated how the problems arise periodically and the indicators in the formation of the city plans of the future. It concludes with some foresights about next fifty years’ city futures of the millennium.

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Evaluating Fatal Overdose Deaths In Orange County Florida From 2019-2021, Brian Hall Jan 2022

Evaluating Fatal Overdose Deaths In Orange County Florida From 2019-2021, Brian Hall

Electronic Theses and Dissertations, 2020-2023

This study sought to investigate fatal overdoses in Orange County, Florida during the years of 2019, 2020, and 2021. Data for this project was provided by the Orange County Medical Examiner's office. Each overdose death was coded for age, sex, race, and cause of death. The purpose of the study is to identify trends to inform policy reform. The results reveal that fentanyl overdose deaths are continuing to rise as heroin overdose deaths decrease. Additionally, there is greater upward trends in polysubstance opioid overdose deaths as compared to non-opioid polysubstance overdose deaths. Ultimately, a specific type of overdose death cannot …

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Reporter Chondrocyte Optimization Of Bioinks For Zonal 3d Bioprinting Of Cartilage, Kari Martyniak Jan 2022

Reporter Chondrocyte Optimization Of Bioinks For Zonal 3d Bioprinting Of Cartilage, Kari Martyniak

Electronic Theses and Dissertations, 2020-2023

Osteoarthritis (OA) is the most common form of arthritis, often thought of as a disease of the elderly, but post traumatic OA predominantly impacts younger individuals. Articular cartilage is the tissue that coats the end of your bones in synovial joints. Since cartilage has limited healing capacity, defects, or injuries to it progressively erodes down to the subchondral bone. Unfortunately, current treatment options all have limitations, particularly for younger patients. Cartilage has a specific zonal architecture that is distinguished by the different cell morphologies and arrangements, biochemical composition, and mechanical properties. 3D bioprinting is a tissue engineering technique that involves …

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Testing The Influence Of Water Depth In Design Of Created Oyster Reef For Living Shoreline Applications, Peter Vien Jan 2022

Testing The Influence Of Water Depth In Design Of Created Oyster Reef For Living Shoreline Applications, Peter Vien

Electronic Theses and Dissertations, 2020-2023

Living shoreline stabilization has become a popular practice in shoreline restoration and bank protection; however, there are still many uncertainties regarding effective site design using living materials. For example, natural wave-breaks may be formed of created reefs, but the optimum water depth for hydrodynamic influence may differ from the preferred depth to ensure organism recruitment. The objective of this research is to understand how water depth relative to the crest of submerged artificial oyster reef structures influences nearshore hydrodynamic processes and sediment transport or retention in nearshore areas. A field study, sited in a microtidal estuary on the Atlantic coast …

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A Social Ecological Approach Towards Empowering Foster Youth To Be Safer Online, Karla Badillo-Urquiola Jan 2022

A Social Ecological Approach Towards Empowering Foster Youth To Be Safer Online, Karla Badillo-Urquiola

Electronic Theses and Dissertations, 2020-2023

Teens in foster care are some of the most vulnerable youth to encounter serious offline risks, such as sex trafficking. Research shows that children who are vulnerable offline are more likely to be vulnerable online. Therefore, it is important to understand how the internet plays a role in how foster youth are exposed to these risks, so that we may develop effective interventions that empower foster youth against becoming victims of these online risks. A comprehensive review of the literature (Chapter 2) emphasized the unique sets of characteristics and challenges of foster youth that create substantial nuance and require a …

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Application Of Biologically Activate Carbon For Treatment Of Sulfide-Laden Groundwater, Jessica Cormier Jan 2022

Application Of Biologically Activate Carbon For Treatment Of Sulfide-Laden Groundwater, Jessica Cormier

Electronic Theses and Dissertations, 2020-2023

Small-system water purveyors must overcome many challenges to provide an adequate and safe water supply to its consuming public. This dissertation reports on research related to the application of biologically activated carbon (BAC) media filters for the treatment of well water to remove disinfection by-product (DBP) precursor matter, measured as dissolved organic carbon (DOC), at two treatment plants serving a small community water system. Four research questions were investigated individually in discrete, yet interconnected studies at two water treatment facilities processing groundwater that contained hydrogen-sulfide (~1.2 mg/L) and dissolved organic carbon (~2.0 mg/L). The first study revealed that BAC filters …

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Compact Lens Technologies: Curved Image Sensor And Volumetric Imaging Efficiency, Zhao Ma Jan 2022

Compact Lens Technologies: Curved Image Sensor And Volumetric Imaging Efficiency, Zhao Ma

Electronic Theses and Dissertations, 2020-2023

Compact image systems bring up people's attention in the field of target recognition, surveillance, situation awareness or even photography. Conventional metrics assess image system based on image quality without considering systems' volume. More comprehensive metrics, such as General Image-Quality Equation and the Targeting Task Performance metric, incorporates all image system components from object, lenses to detector and even imaging processing algorithm. All these key factors prohibit these metrics from being applied to image system in a convenient manner. Here, we propose a simple metric, volumetric imaging efficiency, considering both image quality and volume. Only concentrate on optical lenses enables the …

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Intrahost Diversity Of Staphylococcus Aureus In Carriage Among Native Americans, Julia Webb Jan 2022

Intrahost Diversity Of Staphylococcus Aureus In Carriage Among Native Americans, Julia Webb

Electronic Theses and Dissertations, 2020-2023

Staphylococcus aureus (SA) is an opportunistic pathogen and a commensal member of the human microbiota that frequently colonizes the upper respiratory tract and skin. While SA can cause disease ranging from minor skin infections to life-threatening septicemia, it can also be carried asymptomatically. As carriage is the most significant risk factor for SA disease, surveillance is important for the prevention of outbreaks in vulnerable communities. Native Americans have a greater risk of infectious disease than the general US population, and Native Americans in the Southwestern United States have been shown to experience high rates of invasive SA disease. Here we …

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A Quantitative Examination Of The Relationship Between Curiosity, Cultural Humility, And Multicultural Counseling Competence In Master's-Level Counselors-In-Training Enrolled In Cacrep-Accredited Programs, Amber Haley Jan 2022

A Quantitative Examination Of The Relationship Between Curiosity, Cultural Humility, And Multicultural Counseling Competence In Master's-Level Counselors-In-Training Enrolled In Cacrep-Accredited Programs, Amber Haley

Electronic Theses and Dissertations, 2020-2023

For decades, researchers and counselor educators have emphasized the importance of developing counselors prepared to serve a diverse society. However, there is still much debate around which factors contribute to the development of a culturally competent counselor. The influence of curiosity in the development of competence has been researched in the field of education, however, curiosity has not yet been studied in counseling as it relates to counselors' openness and competence in working with clients perceived as different from themselves. The author conducted a quantitative research study to examine the influence of curiosity and cultural humility in master's level counselors-in-training …

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Curriculum 2013: Addressing The Needs Of High Ability Learners In Indonesian Secondary Schools, Lismawati Lapasi Jan 2022

Curriculum 2013: Addressing The Needs Of High Ability Learners In Indonesian Secondary Schools, Lismawati Lapasi

Electronic Theses and Dissertations, 2020-2023

High ability learners are students with outstanding abilities in one domain or more and have varying learning abilities, interests, and needs. Due to their diversity, these students require curriculum and instruction that can address their needs and facilitate them to reach their full potential. In Indonesia, high ability education is rare to be found as the curriculum is oriented to meet the needs of students of all abilities. However, Indonesia's current national curriculum, Curriculum 2013, has the potential to address the needs of high ability learners in the regular classroom. Using the qualitative literature review method, this study analyzed the …

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A Survival Analysis Examining Risk And Protective Factors Of Foster Care Reentry For Children Aged 0 To 5 Within A Social Ecological Framework, Samantha Klaver Jan 2022

A Survival Analysis Examining Risk And Protective Factors Of Foster Care Reentry For Children Aged 0 To 5 Within A Social Ecological Framework, Samantha Klaver

Electronic Theses and Dissertations, 2020-2023

Although the fundamental goals of the child welfare system include establishing and ensuring the safety, permanency, and well-being of affected children, child reentry into the foster care system has emerged recently as a substantial and growing concern (Jedwab & Shaw, 2017). Utilizing archival, statewide administrative data collected from Florida's Department of Children and Families (DCF), a series of multivariate Cox regression models were conducted on a sample of young children between the ages of 0- and 5-years (N = 3,970) to examine various socioecological risk and protective factors of foster care reentry. Several individual factors (i.e., child age at initial …

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The Empathy Reading Project: Supporting Parents And Their Children Living With Autism Spectrum Disorder, Sarah Mendoza Jan 2022

The Empathy Reading Project: Supporting Parents And Their Children Living With Autism Spectrum Disorder, Sarah Mendoza

Electronic Theses and Dissertations, 2020-2023

Children with ASD benefit from interventions that are interactive and focus on developing social skills, and the parent-child relationship plays a vital part in the development of empathy and social skills. The Empathy Reading Project: Supporting Parents And Their Children Living With Autism Spectrum Disorder (ASD) explored whether parent-led bibliotherapy with therapeutic support from the researcher helped children ages three to five living with ASD improve cognitive empathy and social-emotional development and their parents gain parental acceptance. All participants were parent and child dyads (N=4), and all child participants were male. The Empathy Reading Project was a multiple baseline (A-B-A-B), …

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Remote Learning During Covid-19 On Internal Medicine Residents' Education: Barriers And Enhancements Through Lived Experiences, Stephanie Rivera-Velazquez Jan 2022

Remote Learning During Covid-19 On Internal Medicine Residents' Education: Barriers And Enhancements Through Lived Experiences, Stephanie Rivera-Velazquez

Electronic Theses and Dissertations, 2020-2023

The COVID-19 pandemic uncovered instructional changes within higher education. Accommodations for continued instruction included a transition to remote learning. However, little research exists regarding the experiences of medical residents during this transition in their education while combating the COVID-19 pandemic. This qualitative study, phenomenological in nature, aimed to explore the lived experiences of internal medicine medical residents at one medical college in Central Florida regarding the transition from face-to-face instruction to remote learning due to the COVID-19 pandemic. Eleven participating medical residents underwent semi-structured interviews via Zoom. Garrison's Community of Inquiry conceptual model and Hall and Hord's Concerns-Based Adoption Model …

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Replicating Nature: Functional And Morphological Biomimicry As Blueprints For Synthetic Macromolecular Structures, Erinn Kay Reville Jan 2022

Replicating Nature: Functional And Morphological Biomimicry As Blueprints For Synthetic Macromolecular Structures, Erinn Kay Reville

Doctoral Dissertations

The aim of this dissertation is to provide insight into synthetic materials that replicate the function and structure of natural materials. First, a comprehensive overview of the challenges and recent advances in tailored synthetic molecular recognition through molecularly imprinted polymers (MIPs) will be presented. Chapter 2 of this work discusses the synthesis of azlactone-based homopolymers as functional polymers tuned for the detection of opioid molecules. Through the rapid and efficient ring-opening reaction of azlactone pendant chains with primary amines, customized functionalization of the homopolymers with receptor-like moieties was achieved post-polymerization. Chapter 3 explores the use of functionalized diblock copolymers as …

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Synthesis Of Model Oxepin Substrates For Comparative Two Electron Oxidation Studies With Cytochrome P450 And Cerium Ammonium Nitrate To Investigate Benzene Metabolism, Ryan William Fitzgerald Jan 2022

Synthesis Of Model Oxepin Substrates For Comparative Two Electron Oxidation Studies With Cytochrome P450 And Cerium Ammonium Nitrate To Investigate Benzene Metabolism, Ryan William Fitzgerald

Doctoral Dissertations

Two model oxepins were synthesized in an attempt to model the metabolism of benzene in the human liver. 4,5-Benzoxepin was subjected to similar enzyme reactions that the oxepin metabolite itself would encounter if one was exposed to benzene. In addition, a synthesis of 2,3-benzoxepin was completed in order to compare enzyme and non-enzyme catalyzed reactions with that of 4,5-benzoxepin. In an attempt to test the validity of the enzyme reactions, the model oxepins were also reacted with a two single electron oxidizing inorganic salt, cerium (IV) ammonium nitrate (CAN) to see if the intermediates following the enzyme reaction were consistent. …

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Enhancing Gdf1 Expression With Devil’S Club (Oplopanax Horridus) Extracts In Acute Myeloid Leukemia, Vasiliki Papakotsi Jan 2022

Enhancing Gdf1 Expression With Devil’S Club (Oplopanax Horridus) Extracts In Acute Myeloid Leukemia, Vasiliki Papakotsi

Doctoral Dissertations

Acute myeloid leukemia (AML) is a clonal hematopoietic malignancy with highly heterogeneous molecular and clinical profiles. It is one of the deadliest blood cancers, resulting in approximately 10,000 deaths each year. Impaired hematopoiesis is one of AML’s hallmarks. This entails defective erythropoiesis and proliferation of undifferentiated myeloblasts. AML is also characterized by chemoresistance and high relapse rates. Despite significant advances in treatments, there is no cure for AML. Therefore, there is an emerging and unmet need to shift away from traditional chemotherapeutics and focus on targeted therapies with curative potential. Growth/differentiation factor 1 (GDF1) is a member of the TGFβ …

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The Fate Of Organic Nitrogen In Agroecosystems: Drivers And Outcomes, Lauren C. Breza Jan 2022

The Fate Of Organic Nitrogen In Agroecosystems: Drivers And Outcomes, Lauren C. Breza

Doctoral Dissertations

Enhancing soil nitrogen (N) stocks is critical for managing soil health in agroecosystems. Growers apply external N as synthetic fertilizer to increase the amount of available N to crops. However, it is well known that synthetic fertilizer usage in agroecosystems leads to widespread pollution and contributes significantly to climate change. Nevertheless, growers and researchers recognize this N problem as a global problem and are developing solutions via alternative farming methods. Some of these alternative strategies include cover cropping, diversifying crop rotations, organic farming (i.e., no inputs), or combining these methods. Understanding how the different facets of agricultural management influence the …

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Single Chain Reversible Addition-Fragmentation Chain Transfer (Raft) Poly(N-Isopropylacrylamide) For Chemical Sensing, Tianyu Ren Jan 2022

Single Chain Reversible Addition-Fragmentation Chain Transfer (Raft) Poly(N-Isopropylacrylamide) For Chemical Sensing, Tianyu Ren

Doctoral Dissertations

An approach to single chain poly-N-isopropyl acrylamide (polyNIPAM) with a redox tag was polymerized by the reversible addition fragmentation-chain transfer (RAFT) method. Molecularly imprinted polymers (MIPs) technology is the design of an artificial receptor with high selectivity for a specific analyte. The synthesized RAFT polymers were devised to develop conformation-based electrochemical MIP sensors.The material polyNIPAM is attractive as a receptor of a chemical sensor. Due to its thermosensitive properties, polyNIPAM collapses above the lower critical solution temperature (LCST) and returns to its original state when the temperature is reduced below LCST. This reversible aggregation behavior shows that polyNIPAM has a …

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Application Of Molecular Tools To Assess Toxicity In Industrial Wastewater And Track Viral Pathogens In Municipal Wastewaters, Mina Aghababaei Shahrestani Jan 2022

Application Of Molecular Tools To Assess Toxicity In Industrial Wastewater And Track Viral Pathogens In Municipal Wastewaters, Mina Aghababaei Shahrestani

Doctoral Dissertations

Wastewater is a complex matrix containing a wide range of microorganisms and chemical compounds. For public health purposes, it is critical to monitor for harmful microorganisms and evaluate the toxicity of chemicals present in industrial and municipal wastewaters on human and ecosystem health. Over the past decade, sophisticated technologies such as high-throughput sequencing have enabled the development of molecular tools, which are now widely employed for tracking pathogens and assessing toxicity of municipal and industrial wastewaters. Molecular tools for biomonitoring of wastewater are designed to target specific microbial biomarkers including nucleic acids, proteins and antigens. Accordingly, this dissertation applied molecular …

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Essential Factors For A Healthy Microbiome: A Scoping Review, Patricia Grace-Farfaglia, Heather Frazier, Maura D. Iversen Jan 2022

Essential Factors For A Healthy Microbiome: A Scoping Review, Patricia Grace-Farfaglia, Heather Frazier, Maura D. Iversen

Health Science Faculty Publications

Recent discoveries of the purpose and potential of microbial interactions with humans have broad implications for our understanding of metabolism, immunity, the host–microbe genetic interactions. Bioavailability and bioaccessibility of phytonutrients in foods not only enrich microbial diversity in the lower human gastrointestinal tract (GIT) but also direct the functioning of the metagenome of the microbiota. Thus, healthy choices must include foods that contain nutrients that satisfy both the needs of humans and their microbes. Physical activity interventions at a moderate level of intensity have shown positive effects on metabolism and the microbiome, while intense training (>70% VO2max) …

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Integrating Behavior And Genomics To Understand Sensory Integration In Cnidarians, Sydney Birch Jan 2022

Integrating Behavior And Genomics To Understand Sensory Integration In Cnidarians, Sydney Birch

Doctoral Dissertations

Class Hydrozoa belongs to Phylum Cnidaria which occupies a key phylogenetic position in animal evolution. Phylum Cnidaria, which includes animals such as jellyfish, sea anemones, corals, and hydrozoans, is the evolutionary sister lineage to bilaterians. My Ph.D. research is focused on understanding how hydrozoans integrate sensory information from the environment at the genetic level and how that mediates an organismal behavioral response by investigating three closely related hydrozoan species: Hydractinia symbiolongicarpus, Hydra vulgaris, and Ectopleura crocea. Many of the studies on cnidarian sensory ecology have focused on adult stages or anthozoan species (sea anemones and corals) leaving a lack of …

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Neighborhood Disorder And Adolescent Psychological Distress: Effects Of Gender, Race/Ethnicity, Social Support, And Self Concept, Jean Bessette Jan 2022

Neighborhood Disorder And Adolescent Psychological Distress: Effects Of Gender, Race/Ethnicity, Social Support, And Self Concept, Jean Bessette

Doctoral Dissertations

Sociological research on mental health is often guided by the stress process framework. A key tenet of this paradigm is the proposition that both exposure and vulnerability to social stressors arise from one’s placement in the social structure; those with lower social status face greater exposure and/or greater vulnerability to stressors that detrimentally impact their psychological wellbeing. A consequential social stressor is the neighborhood context in which one resides. Past research has suggested a disadvantageous effect of greater neighborhood physical and social disorder on youth mental health. This research employs the stress process framework to examine how the effects of …

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2022-2023 Halmos College Of Arts And Sciences Graduate Program Catalog, Nova Southeastern University Jan 2022

2022-2023 Halmos College Of Arts And Sciences Graduate Program Catalog, Nova Southeastern University

Halmos College of Arts and Sciences Course Catalogs

No abstract provided.

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The Sequence Dependent Nanoscale Structure Of Cenp-A Nucleosomes, Tommy Stormberg, Yuri L. Lyubchenko Jan 2022

The Sequence Dependent Nanoscale Structure Of Cenp-A Nucleosomes, Tommy Stormberg, Yuri L. Lyubchenko

Journal Articles: Pharmaceutical Sciences

CENP-A is a histone variant found in high abundance at the centromere in humans. At the centromere, this histone variant replaces the histone H3 found throughout the bulk chromatin. Additionally, the centromere comprises tandem repeats of α-satellite DNA, which CENP-A nucleosomes assemble upon. However, the effect of the DNA sequence on the nucleosome assembly and centromere formation remains poorly understood. Here, we investigated the structure of nucleosomes assembled with the CENP-A variant using Atomic Force Microscopy. We assembled both CENP-A nucleosomes and H3 nucleosomes on a DNA substrate containing an α-satellite motif and characterized their positioning and wrapping efficiency. We …

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